miximash: Mixtures of Independent Components in Multivariate Adaptive Shrinkage

This R package implements statistical methods that generalize the Cormotif model for jointly analyzing differential gene expression in multiple studies or under multiple experimental conditions (e.g., measured in different cell types). Model fitting procedures are implemented using expectation maximization (EM).

License

All source code and software in this repository are made available under the terms of the MIT license.

Quick Start

1. Install the R package from the Github repository using devtools:

library("devtools")
install_github("stephenslab/miximash")

2. Add more steps here.

How to update the package documentation

Within a local copy of this repository, run the following R commands:

library(devtools)
document()

How to test the package build

R CMD build miximash
R CMD check --as-cran miximash_0.1-1.tar.gz

Credits

This R package was developed by Zhiwei Ma at the University of Chicago, with contributions from Peter Carbonetto and Matthew Stephens.