(EN) We aim to assess consciousness in wakefulness, deep sedation, and intermediate levels through biomarkers of electrical and hemodynamical brain activity using a synchronized EEG and fNIRS system during a surgical procedure (colonoscopy and endoscopy) under only propofol anesthesia.
(ES) El objetivo de este proyecto es detectar la conciencia en vigilia, sedación profunda y niveles intermedios a través de biomarcadores de actividad cerebral eléctrica y hemodinámica utilizando un sistema de EEG y fNIRS sincronizado durante un procedimiento quirúrgico (colonoscopia y endoscopia) bajo anestesia con solo propofol.
- Poster presentation for the Real-Time Functional Imaging and Neurofeedback meeting (rtFIN2022) at Yale University in New Haven, Connecticut, USA. October 17 - 21, 2022 [https://rtfin2022.squarespace.com/].
- Poster - Figure 1: Methods
- Poster - Figure 2: Classifier - F1 score
- EEG: Neuroscan; active Ag/AgCl electrodes.
- fNIRS: NIRSport1; 8 emitters, 8 detectors optodes.
we are working with the Python library MNE-Python
- Alkire, Michael T, Hudetz, A. G., & Tononi, G. (2008). Consciousness and anesthesia. Science, 322(5903), 876–880. https://doi.org/10.1126/science.1149213
- Davidson, A. J. (2011). Anesthesia and neurotoxicity to the developing brain: the clinical relevance. Paediatric Anaesthesia, 21(7), 716–721. https://doi.org/10.1111/j.1460-9592.2010.03506.x
- Sebel, P. S., Bowdle, T. A., Ghoneim, M. M., Rampil, I. J., Padilla, R. E., Gan, T. J., & Domino, K. B. (2004). The incidence of awareness during anesthesia: a multicenter United States study. Anesthesia and Analgesia, 99(3), 833–839. https://doi.org/10.1213/01.ANE.0000130261.90896.6C
- Xie, G., Deschamps, A., Backman, S. B., Fiset, P., Chartrand, D., Dagher, A., & Plourde, G. (2011). Critical involvement of the thalamus and precuneus during restoration of consciousness with physostigmine in humans during propofol anaesthesia: a positron emission tomography study. British Journal of Anaesthesia, 106(4), 548-557. https://doi.org/10.1093/bja/aeq415
Feel free to submit or comment on any issues of this repository.
We are currently looking for new systems to work with and upgrade our hybrid ("DIY") system to detect levels of consciousness during anesthesia.
IF YOU WISH TO SUPPORT US, please contact any of the authors:
- Catalina Saini ([email protected]) (https://github.com/catalinasaini)
- Carlos Valle ([email protected]) (https://github.com/CarlosValleA)
- Gabriela Vargas ([email protected]) (https://github.com/galadriana)