py3tuio is a very basic, crude and compact implementation of a TUIO 1.x client written in Python 3 using pyliblo. It is restricted to 2D surfaces and does not distinguish between different servers.
The TUIO protocol is based on the OSC (Open Sound Control) protocol. liblo is a popular and lightweight OSC implementation. Pyliblo is a Python wrapper for liblo. To use py3tuio in your project, install liblo first, then pyliblo.
You may want to use one or two package managers to do this:
brew install liblo
pip3 install pyliblo
Type python3 py3tuio.py in your terminal.
Get a TUIO simulator. Try TuioPad if you want to capture data from iOS devices.
Back in 2012 I couldn't find any TUIO client written in python 3.