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antigen.gene / antigen.species mix up for some human epitopes #368

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JamieHeather opened this issue May 30, 2024 · 1 comment
Open

antigen.gene / antigen.species mix up for some human epitopes #368

JamieHeather opened this issue May 30, 2024 · 1 comment
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vdjdb-records-formatting&proofreading Typos and errors that need to be fixed in one or multiple VDJdb records

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@JamieHeather
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I've just updated an analysis to use the May 2024 release and noticed that there's a few entries for anti-human TCRs that appear to have the antigen.gene and antigen.species fields swapped around. There's just under 90 of them, from a handful of different sources - see switched-antigen-gene-species.txt.

(In double checking this I also noticed that sometimes a human protein name is used instead of the gene name in the antigen.gene field, e.g. p53 instead of TP53 or NY-ESO-1 instead of CTAG1B. I'm not sure if it matters, but I guess it's worth maybe flagging for people who want to cross-reference between datasets by gene symbols.)

@mikessh
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mikessh commented May 30, 2024

Yep, just spotted that too, sorry - got a bit distracted with Docker issues) It matters as some "self-antigens" become missing. Thanks for the fix!

@mikessh mikessh added the vdjdb-records-formatting&proofreading Typos and errors that need to be fixed in one or multiple VDJdb records label May 30, 2024
mikessh added a commit that referenced this issue May 30, 2024
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Labels
vdjdb-records-formatting&proofreading Typos and errors that need to be fixed in one or multiple VDJdb records
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