This guide details which macro systems are supported in Scheme, and when and how to use each of them.
Other Lisp dialects such as Common Lisp generally specify a simple macro system in which all macros in that language are written. These macro systems are non-hygienic, which means that macro definitions must be careful not to capture identifiers (symbols) at the macro call site that happen to have the same name.
To combat the problem of variable capture, Scheme implementations have a long tradition of hygienic macros which make sure the identifiers used in macro definitions are automatically distinct from any like-named identifiers at the call site.
Unfortunately hygienic macros are a complex topic and no particular macro system has been agreed upon as the best. Hence one Scheme implementation can support more than one macro system, and in fact the bigger ones generally do. This fact can be quite confusing to people coming from other Lisps, and is worth emphasizing.
Some Scheme programmers are especially passionate about hygienic macros and feel that hygiene is one of the essential features that make Scheme a good language.
However, such praise is not universal. In the opposite camp, a handful of Schemers believe the problems avoided by hygienic macros are not serious enough to justify the complexity of hygienic macro systems. (Even fans of hygienic macros generally concede that they add significant complexity.) Hence a handful of Scheme implementations do not have a hygienic macro system at all. These are generally small implementations: large implementations tend to favor giving programmers more alternatives of all kinds.
Perhaps the majority of Schemers do not feel particularly strongly about the topic. Most prefer hygienic macros where available but are not picky about it. They think hygienic macros are just one of Scheme’s many useful features, and the language has plenty to offer even without them.
Some Scheme implementations have a define-macro which is almost identical to the defmacro in Common Lisp, Emacs Lisp, and Clojure. It is a simple, non-hygienic macro system true to the wider Lisp tradition.
The first Scheme standard to tackle macros was R4RS (1991). It said that macros may be defined using define-syntax (note: define-syntax is different from define-macro). It also said the syntax-rules macro system must be supported by all implementations of the standard. syntax-rules is a simple yet surprisingly effective hygienic macro system based on pattern-matching and rewriting. Both define-syntax and syntax-rules have been a part of standard Scheme ever since.
R6RS (2007) added a more complex macro system called syntax-case in addition to the old syntax-rules. syntax-case can run arbitrary Scheme code to build the macro expansion while maintaining hygiene by default.
The small edition of the R7RS language provides only define-syntax and syntax-rules. The R7RS large language (work in progress) may also provide either syntax-case or another powerful hygienic macro system.
Some Scheme implementations have ir-macro-transformer and/or er-macro-transformer as an alternative to syntax-case.
Generally the best approach is to try writing a macro using syntax-rules first. It’s simple to use and works well for most common tasks.
If you run into its limitations, try syntax-case which is hygienic and a standard part of R6RS.
If syntax-case is not available in the Scheme implementation you need, find out if it has er-macro-transformer.
Finally, define-macro should get any job done in a pinch. People who are Lisp programmers but not Scheme aficionados should also be able to help you with define-macro, whereas the hygienic macro systems are not instantly recognizable to other Lispers. If you are coming to Scheme from another Lisp, it may be best to start with define-macro and work your way up to syntax-rules and then syntax-case.