diff --git a/python/cudf/cudf/core/dataframe.py b/python/cudf/cudf/core/dataframe.py
index 14b63c2b0d7..d54a800aedf 100644
--- a/python/cudf/cudf/core/dataframe.py
+++ b/python/cudf/cudf/core/dataframe.py
@@ -414,8 +414,9 @@ def _setitem_tuple_arg(self, key, value):
                     )
 
             else:
-                value = cupy.asarray(value)
-                if value.ndim == 2:
+                if not is_column_like(value):
+                    value = cupy.asarray(value)
+                if getattr(value, "ndim", 1) == 2:
                     # If the inner dimension is 1, it's broadcastable to
                     # all columns of the dataframe.
                     indexed_shape = columns_df.loc[key[0]].shape
@@ -558,8 +559,9 @@ def _setitem_tuple_arg(self, key, value):
         else:
             # TODO: consolidate code path with identical counterpart
             # in `_DataFrameLocIndexer._setitem_tuple_arg`
-            value = cupy.asarray(value)
-            if value.ndim == 2:
+            if not is_column_like(value):
+                value = cupy.asarray(value)
+            if getattr(value, "ndim", 1) == 2:
                 indexed_shape = columns_df.iloc[key[0]].shape
                 if value.shape[1] == 1:
                     if value.shape[0] != indexed_shape[0]:
diff --git a/python/cudf/cudf/tests/test_indexing.py b/python/cudf/cudf/tests/test_indexing.py
index 716b4dc6acd..9df2852dde8 100644
--- a/python/cudf/cudf/tests/test_indexing.py
+++ b/python/cudf/cudf/tests/test_indexing.py
@@ -2369,3 +2369,13 @@ def test_duplicate_labels_raises():
         df[["a", "a"]]
     with pytest.raises(ValueError):
         df.loc[:, ["a", "a"]]
+
+
+@pytest.mark.parametrize("indexer", ["iloc", "loc"])
+@pytest.mark.parametrize("dtype", ["category", "timedelta64[ns]"])
+def test_loc_iloc_setitem_col_slice_non_cupy_types(indexer, dtype):
+    df_pd = pd.DataFrame(range(2), dtype=dtype)
+    df_cudf = cudf.DataFrame.from_pandas(df_pd)
+    getattr(df_pd, indexer)[:, 0] = getattr(df_pd, indexer)[:, 0]
+    getattr(df_cudf, indexer)[:, 0] = getattr(df_cudf, indexer)[:, 0]
+    assert_eq(df_pd, df_cudf)