diff --git a/src/prompt_toolkit/application/application.py b/src/prompt_toolkit/application/application.py
index bcc819095..cf5bd077d 100644
--- a/src/prompt_toolkit/application/application.py
+++ b/src/prompt_toolkit/application/application.py
@@ -958,7 +958,13 @@ def run_in_thread() -> None:
             # See whether a loop was installed already. If so, use that. That's
             # required for the input hooks to work, they are installed using
             # `set_event_loop`.
-            loop = asyncio.get_event_loop()
+            if sys.version_info < (3, 10):
+                loop = asyncio.get_event_loop()
+            else:
+                try:
+                    loop = asyncio.get_running_loop()
+                except RuntimeError:
+                    loop = asyncio.new_event_loop()
         except RuntimeError:
             # No loop installed. Run like usual.
             return asyncio.run(coro)
diff --git a/src/prompt_toolkit/input/win32.py b/src/prompt_toolkit/input/win32.py
index 9ad72aee1..35e8948d2 100644
--- a/src/prompt_toolkit/input/win32.py
+++ b/src/prompt_toolkit/input/win32.py
@@ -314,10 +314,10 @@ def _get_keys(
 
                 # Process if this is a key event. (We also have mouse, menu and
                 # focus events.)
-                if type(ev) == KEY_EVENT_RECORD and ev.KeyDown:
+                if isinstance(ev, KEY_EVENT_RECORD) and ev.KeyDown:
                     yield from self._event_to_key_presses(ev)
 
-                elif type(ev) == MOUSE_EVENT_RECORD:
+                elif isinstance(ev, MOUSE_EVENT_RECORD):
                     yield from self._handle_mouse(ev)
 
     @staticmethod
@@ -379,7 +379,7 @@ def _event_to_key_presses(self, ev: KEY_EVENT_RECORD) -> list[KeyPress]:
         """
         For this `KEY_EVENT_RECORD`, return a list of `KeyPress` instances.
         """
-        assert type(ev) == KEY_EVENT_RECORD and ev.KeyDown
+        assert isinstance(ev, KEY_EVENT_RECORD) and ev.KeyDown
 
         result: KeyPress | None = None