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getExperimentCrossAssociation to ignore 0s? #390

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antagomir opened this issue Jul 15, 2023 · 1 comment
Open

getExperimentCrossAssociation to ignore 0s? #390

antagomir opened this issue Jul 15, 2023 · 1 comment
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@antagomir
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In ecological studies the association analyses are sometimes carried out only for those samples that have observations (of a given species for instance).

It would be useful to allow association analyses, ignoring zeroes in one or both data sets via an additional argument.

This is also not straightfwd to do before calling the correlation function since different features may have observations in different samples. Automation would take user a long way.

This applies especially between associations of taxa (to other taxa, or other omics / phenotypes).

@antagomir
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Some literature refs on this aspect of ecological studies could be added in manpage reference list.

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