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- , - - Annotations: , - "http://orcid.org/0000-0003-2689-5511"^^xsd:string, - "2016-10-26"^^xsd:string - - , - - Annotations: , + Annotations: , "http://orcid.org/0000-0003-2689-5511"^^xsd:string, "2016-10-26"^^xsd:string - + Individual: @@ -250,9 +238,10 @@ Individual: Individual: Annotations: - "2016-10-26"^^xsd:string, - "848"^^xsd:string, - "http://orcid.org/0000-0003-2689-5511"^^xsd:string + "761.75"^^xsd:string, + "38"^^xsd:string, + "http://orcid.org/0000-0003-2689-5511"^^xsd:string, + "2016-11-01"^^xsd:string Types: @@ -300,9 +289,9 @@ Individual: Annotations: "http://orcid.org/0000-0003-2689-5511"^^xsd:string, rdfs:comment "Excess T3, sensed by this receptor, involved in apoptosis of cone cells"^^xsd:string, - "428"^^xsd:string, - "2016-10-26"^^xsd:string, - "373"^^xsd:string + "261"^^xsd:string, + "484"^^xsd:string, + "2016-11-01"^^xsd:string Types: @@ -359,29 +348,6 @@ Individual: -Individual: - - Annotations: - "PMID:20203194"^^xsd:string, - "http://orcid.org/0000-0003-2689-5511"^^xsd:string, - "2016-10-25"^^xsd:string - - Types: - - - -Individual: - - Annotations: - "PMID:20203194"^^xsd:string, - "2016-10-26"^^xsd:string, - "http://orcid.org/0000-0003-2689-5511"^^xsd:string, - "MGI:2664293"^^xsd:string - - Types: - - - Individual: Annotations: @@ -394,18 +360,6 @@ Individual: -Individual: - - Annotations: - "PMID:20203194"^^xsd:string, - "http://orcid.org/0000-0003-2689-5511"^^xsd:string, - "2016-10-26"^^xsd:string, - "MGI:2664293"^^xsd:string - - Types: - - - Individual: Annotations: @@ -439,3 +393,15 @@ Individual: +Individual: + + Annotations: + "http://orcid.org/0000-0003-2689-5511"^^xsd:string, + "MGI:2657173"^^xsd:string, + "PMID:20203194"^^xsd:string, + "2016-10-26"^^xsd:string + + Types: + + + diff --git a/models/580fe05a00000077 b/models/580fe05a00000077 index 003a22194b50..38dadc5f6008 100644 --- a/models/580fe05a00000077 +++ b/models/580fe05a00000077 @@ -14,10 +14,10 @@ Annotations: Annotations: 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This plasmid DNA nicking activity required the presence\\nof Mg 2+ and was not observed when GST–DCR-1(D1472E) was incubated with CED-3 (Fig. 3B, left, top, lanes 5, 7, 8), which indicated that CED-3 cleavage is required to activate this new Mg 2+-dependent DNase activity of DCR-1. \"}]},{\"subject\":\"gomodel:580fe05a00000077/580fe05a00000091\",\"property\":\"BFO:0000050\",\"property-label\":\"part_of\",\"object\":\"gomodel:580fe05a00000077/580fe05a00000098\",\"annotations\":[{\"key\":\"evidence\",\"value\":\"gomodel:580fe05a00000077/580fe05a00000099\",\"value-type\":\"IRI\"},{\"key\":\"contributor\",\"value\":\"http://orcid.org/0000-0002-1706-4196\"},{\"key\":\"date\",\"value\":\"2016-10-31\"},{\"key\":\"comment\",\"value\":\"ES (PMID:20223951): [35S]Met-labeled GST–DCR-1was cleaved by CED-3, which yielded two primary cleavage products of about 193 and 43 kD (Fig. 3A, lanes 1 and 2).\"}]},{\"subject\":\"gomodel:580fe05a00000077/580fe05a00000089\",\"property\":\"BFO:0000050\",\"property-label\":\"part_of\",\"object\":\"gomodel:580fe05a00000077/580fe05a00000090\",\"annotations\":[{\"key\":\"evidence\",\"value\":\"gomodel:580fe05a00000077/580fe05a00000097\",\"value-type\":\"IRI\"},{\"key\":\"contributor\",\"value\":\"http://orcid.org/0000-0002-1706-4196\"},{\"key\":\"date\",\"value\":\"2016-10-31\"},{\"key\":\"comment\",\"value\":\"ES (PMID:20223951): We observed significantly fewer cell corpses in both dcr-1(ok247) and dcr-1(pk1351) mutants at most embryonic stages than in wild-type embryos (Fig. 2A).\"}]},{\"subject\":\"gomodel:580fe05a00000077/580fe05a00000091\",\"property\":\"RO:0002333\",\"property-label\":\"enabled_by\",\"object\":\"gomodel:580fe05a00000077/580fe05a00000092\",\"annotations\":[{\"key\":\"evidence\",\"value\":\"gomodel:580fe05a00000077/580fe05a00000093\",\"value-type\":\"IRI\"},{\"key\":\"contributor\",\"value\":\"http://orcid.org/0000-0002-1706-4196\"},{\"key\":\"date\",\"value\":\"2016-10-31\"},{\"key\":\"comment\",\"value\":\"ES (PMID:20223951): [35S]Met-labeled GST–DCR-1was cleaved by CED-3, which yielded two primary cleavage products of about 193 and 43 kD (Fig. 3A, lanes 1 and 2).\"}]},{\"subject\":\"gomodel:580fe05a00000077/580fe05a00000087\",\"property\":\"RO:0002213\",\"property-label\":\"positively regulates\",\"object\":\"gomodel:580fe05a00000077/580fe05a00000100\",\"annotations\":[{\"key\":\"contributor\",\"value\":\"http://orcid.org/0000-0002-1706-4196\"},{\"key\":\"date\",\"value\":\"2016-10-31\"}]},{\"subject\":\"gomodel:580fe05a00000077/580fe05a00000087\",\"property\":\"RO:0002333\",\"property-label\":\"enabled_by\",\"object\":\"gomodel:580fe05a00000077/580fe05a00000088\",\"annotations\":[{\"key\":\"evidence\",\"value\":\"gomodel:580fe05a00000077/580fe05a00000095\",\"value-type\":\"IRI\"},{\"key\":\"contributor\",\"value\":\"http://orcid.org/0000-0002-1706-4196\"},{\"key\":\"date\",\"value\":\"2016-10-31\"},{\"key\":\"comment\",\"value\":\"ES (PMID:20223951): Incubation of CED-3 with GST–DCR-1 resulted in nicking of the plasmid DNA and the mobility shift of the plasmid DNA from the supercoiled form (SC) to the nicked open circle form (Fig. 3B, left, top, lane 4). This plasmid DNA nicking activity required the presence of Mg 2+ and was not observed when GST–DCR-1(D1472E) was incubated with CED-3 (Fig. 3B, left, top, lanes 5, 7, 8), which indicated that CED-3 cleavage is required to activate this new Mg 2+-dependent DNase activity of DCR-1. \"}]},{\"subject\":\"gomodel:580fe05a00000077/580fe05a00000158\",\"property\":\"BFO:0000050\",\"property-label\":\"part_of\",\"object\":\"gomodel:580fe05a00000077/580fe05a00000161\",\"annotations\":[{\"key\":\"contributor\",\"value\":\"http://orcid.org/0000-0002-1706-4196\"},{\"key\":\"date\",\"value\":\"2016-11-01\"}]},{\"subject\":\"gomodel:580fe05a00000077/580fe05a00000158\",\"property\":\"BFO:0000050\",\"property-label\":\"part_of\",\"object\":\"gomodel:580fe05a00000077/580fe05a00000162\",\"annotations\":[{\"key\":\"evidence\",\"value\":\"gomodel:580fe05a00000077/580fe05a00000163\",\"value-type\":\"IRI\"},{\"key\":\"contributor\",\"value\":\"http://orcid.org/0000-0002-1706-4196\"},{\"key\":\"date\",\"value\":\"2016-11-01\"}]},{\"subject\":\"gomodel:580fe05a00000077/580fe05a00000087\",\"property\":\"BFO:0000050\",\"property-label\":\"part_of\",\"object\":\"gomodel:580fe05a00000077/580fe05a00000089\",\"annotations\":[{\"key\":\"evidence\",\"value\":\"gomodel:580fe05a00000077/580fe05a00000096\",\"value-type\":\"IRI\"},{\"key\":\"contributor\",\"value\":\"http://orcid.org/0000-0002-1706-4196\"},{\"key\":\"date\",\"value\":\"2016-10-31\"},{\"key\":\"comment\",\"value\":\"ES (PMID:20223951): Incubation of CED-3 with GST–DCR-1 resulted in nicking of the plasmid DNA and the mobility shift of the plasmid DNA from the supercoiled form (SC) to the nicked open circle form (Fig. 3B, left, top, lane 4). This plasmid DNA nicking activity required the presence of Mg 2+ and was not observed when GST–DCR-1(D1472E) was incubated with CED-3 (Fig. 3B, left, top, lanes 5, 7, 8), which indicated that CED-3 cleavage is required to activate this new Mg 2+-dependent DNase activity of DCR-1. \"}]},{\"subject\":\"gomodel:580fe05a00000077/580fe05a00000078\",\"property\":\"BFO:0000050\",\"property-label\":\"part_of\",\"object\":\"gomodel:580fe05a00000077/580fe05a00000082\",\"annotations\":[{\"key\":\"evidence\",\"value\":\"gomodel:580fe05a00000077/580fe05a00000085\",\"value-type\":\"IRI\"},{\"key\":\"contributor\",\"value\":\"http://orcid.org/0000-0002-1706-4196\"},{\"key\":\"date\",\"value\":\"2016-10-31\"},{\"key\":\"comment\",\"value\":\"ES (PMID:20223951): Incubation of CED-3 with GST–DCR-1 resulted in nicking of the plasmid DNA and the mobility shift of the plasmid DNA from the supercoiled form (SC) to the nicked open circle form (Fig. 3B, left, top, lane 4). This plasmid DNA nicking activity required the presence of Mg 2+ and was not observed when GST–DCR-1(D1472E) was incubated with CED-3 (Fig. 3B, left, top, lanes 5, 7, 8), which indicated that CED-3 cleavage is required to activate this new Mg 2+-dependent DNase activity of DCR-1. \"}]},{\"subject\":\"gomodel:580fe05a00000077/580fe05a00000100\",\"property\":\"RO:0002333\",\"property-label\":\"enabled_by\",\"object\":\"gomodel:580fe05a00000077/580fe05a00000101\",\"annotations\":[{\"key\":\"contributor\",\"value\":\"http://orcid.org/0000-0002-1706-4196\"},{\"key\":\"date\",\"value\":\"2016-10-31\"}]},{\"subject\":\"gomodel:580fe05a00000077/580fe05a00000158\",\"property\":\"RO:0002333\",\"property-label\":\"enabled_by\",\"object\":\"gomodel:580fe05a00000077/580fe05a00000159\",\"annotations\":[{\"key\":\"evidence\",\"value\":\"gomodel:580fe05a00000077/580fe05a00000160\",\"value-type\":\"IRI\"},{\"key\":\"contributor\",\"value\":\"http://orcid.org/0000-0002-1706-4196\"},{\"key\":\"date\",\"value\":\"2016-11-01\"},{\"key\":\"comment\",\"value\":\"ES (PMID:20223951): Incubation of CED-3 with GST–DCR-1 resulted in nicking of the plasmid DNA and the mobility shift of the plasmid DNA from the supercoiled form (SC) to the nicked open circle form (Fig. 3B, left, top, lane 4). 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This plasmid DNA nicking activity required the presence of Mg 2+ and was not observed when GST–DCR-1(D1472E) was incubated with CED-3 (Fig. 3B, left, top, lanes 5, 7, 8), which indicated that CED-3 cleavage is required to activate this new Mg 2+-dependent DNase activity of DCR-1. 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