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DESCRIPTION
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DESCRIPTION
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Package: updog
Title: Flexible Genotyping for Polyploids
Version: 2.1.5
Authors@R: person("David",
"Gerard",
email = "[email protected]",
role = c("aut", "cre"),
comment = c(ORCID = "0000-0001-9450-5023"))
Description: Implements empirical Bayes approaches to genotype
polyploids from next generation sequencing data while
accounting for allele bias, overdispersion, and sequencing
error. The main functions are flexdog() and multidog(),
which allow the specification
of many different genotype distributions. Also provided are functions to
simulate genotypes, rgeno(), and read-counts, rflexdog(), as well as
functions to calculate oracle genotyping error rates, oracle_mis(), and
correlation with the true genotypes, oracle_cor(). These latter two
functions are useful for read depth calculations. Run
browseVignettes(package = "updog") in R for example usage. See
Gerard et al. (2018) <doi:10.1534/genetics.118.301468> and
Gerard and Ferrao (2020) <doi:10.1093/bioinformatics/btz852> for details
on the implemented methods.
Depends: R (>= 3.4.0)
License: GPL-3
BugReports: https://github.com/dcgerard/updog/issues
URL: https://github.com/dcgerard/updog/
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.2.3
LinkingTo: Rcpp,
RcppArmadillo
Imports:
Rcpp (>= 0.12.16),
RcppArmadillo,
assertthat,
ggplot2,
reshape2,
foreach,
future,
doFuture,
doRNG,
methods,
iterators
Suggests:
covr,
testthat,
SuppDists,
knitr,
rmarkdown,
VariantAnnotation,
GenomicRanges,
S4Vectors,
IRanges
VignetteBuilder: knitr