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DESCRIPTION
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DESCRIPTION
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Package: seqgendiff
Type: Package
Title: RNA-Seq Generation/Modification for Simulation
Version: 1.2.4
Authors@R: person("David", "Gerard", email = "[email protected]", role = c("aut", "cre"), comment = c(ORCID = "0000-0001-9450-5023"))
Description: Generates/modifies RNA-seq data for use in simulations. We provide
a suite of functions that will add a known amount of signal to a real
RNA-seq dataset. The advantage of using this approach over simulating under
a theoretical distribution is that common/annoying aspects of the data
are more preserved, giving a more realistic evaluation of your method.
The main functions are select_counts(), thin_diff(), thin_lib(),
thin_gene(), thin_2group(), thin_all(), and effective_cor(). See
Gerard (2020) <doi:10.1186/s12859-020-3450-9> for details on the
implemented methods.
License: GPL-3
Encoding: UTF-8
URL: https://github.com/dcgerard/seqgendiff
BugReports: https://github.com/dcgerard/seqgendiff/issues
RoxygenNote: 7.3.1
Suggests:
covr,
testthat (>= 2.1.0),
SummarizedExperiment,
DESeq2,
knitr,
rmarkdown,
airway,
limma,
qvalue,
edgeR
Imports:
assertthat,
irlba,
sva,
pdist,
matchingR,
clue
VignetteBuilder: knitr