Exploring analysis and final results
iCCA classification: cell differentiation-based: Morphology and/or phenotype;
SBD: small bile duct (interlobular to steptal duct);
CLC: Bile ductules/CoH;
DPM: Ductal plate malformation
HCC-like, iCCA with morphological features resembing classical HCC.
Evaluate in 5% increasements Group classifcation:
- SBD (>95%) = pure SBD
- cSBD-CLC (5% < CLC <= 80%] without DPM
- CLC, CLC >80% (consensus paper, WHO)
- iCCA with DPM, >5% DPM
- HCC-like (>95% Hepatoid/HCC-like pattern In addition: All iCCA with > 5% CLC => iCCA with CLC pattern
Note CLC = bile ductular (BD) in some codes