runBP.ipynb

{
 "cells": [
  {
   "cell_type": "code",
   "execution_count": 3,
   "id": "9bba8b64",
   "metadata": {
    "collapsed": true
   },
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "'getOption(\"repos\")' replaces Bioconductor standard repositories, see\n",
      "'?repositories' for details\n",
      "\n",
      "replacement repositories:\n",
      "    CRAN: https://cran.r-project.org\n",
      "\n",
      "\n",
      "Bioconductor version 3.14 (BiocManager 1.30.18), R 4.1.3 (2022-03-10)\n",
      "\n",
      "Installing package(s) 'tidyverse'\n",
      "\n",
      "also installing the dependencies ‘rematch’, ‘gargle’, ‘cellranger’, ‘ids’, ‘vroom’, ‘tzdb’, ‘selectr’, ‘broom’, ‘dtplyr’, ‘forcats’, ‘googledrive’, ‘googlesheets4’, ‘haven’, ‘modelr’, ‘readr’, ‘readxl’, ‘reprex’, ‘rvest’\n",
      "\n",
      "\n",
      "Updating HTML index of packages in '.Library'\n",
      "\n",
      "Making 'packages.html' ...\n",
      " done\n",
      "\n",
      "Old packages: 'FNN', 'gtools', 'randomForest'\n",
      "\n"
     ]
    }
   ],
   "source": [
    "# BiocManager::install(\"tidyverse\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 1,
   "id": "2b104f93",
   "metadata": {},
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "Loading required package: snowfall\n",
      "\n",
      "Loading required package: snow\n",
      "\n",
      "Warning message:\n",
      "“replacing previous import ‘gplots::lowess’ by ‘stats::lowess’ when loading ‘TED’”\n"
     ]
    }
   ],
   "source": [
    "# library(SingleCellExperiment)\n",
    "# library(devtools)\n",
    "library(TED)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 21,
   "id": "ab3372f3",
   "metadata": {},
   "outputs": [],
   "source": [
    "#load in BP demo data in vignette\n",
    "load(\"/home/cke/BPexample_gbm.rdata\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 2,
   "id": "5df8c9aa",
   "metadata": {},
   "outputs": [],
   "source": [
    "df_Puram<-read.table(\"/home/cke/Real/InputToWrapper/real_scRNAref.tsv\",sep='\\t',header=TRUE,row.names = 1,check.names = FALSE)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 3,
   "id": "ca9ab223",
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "data": {
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       "\t<tr><th scope=row>HN25_P25_B12_S312_comb</th><td>0.000000</td><td>1473.4371</td><td>  0.0000000</td><td>0.000000</td><td>  0.000000</td><td>   4.119999</td><td>  0.000000</td><td> 0.4800021</td><td>0</td><td>0.000000</td><td>⋯</td><td>0</td><td> 0.35000166</td><td> 75.771600</td><td>0</td><td> 14.1998820</td><td>  0.000000</td><td>418.52280</td><td> 28.989887</td><td> 11.7407250</td><td> 0.00000</td></tr>\n",
       "\t<tr><th scope=row>⋮</th><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋱</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_A08_S104_comb</th><td>0</td><td> 469.1814</td><td>  0.000000</td><td>0</td><td>  0.00000</td><td>  0.00000</td><td>  0.000000</td><td> 0.0000000</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td> 0.0000000</td><td> 63.737576</td><td>0</td><td> 54.620860</td><td> 53.899296</td><td> 920.3489</td><td>311.53415</td><td>107.6965400</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_E10_S154_comb</th><td>0</td><td>1168.4935</td><td>  0.000000</td><td>0</td><td>  0.00000</td><td>  0.00000</td><td>  0.000000</td><td> 0.7299994</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td> 0.7800211</td><td>256.820950</td><td>0</td><td>  0.000000</td><td> 89.721180</td><td> 494.7160</td><td>131.82108</td><td>  2.2299626</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_E02_S146_comb</th><td>0</td><td> 825.4607</td><td>  0.000000</td><td>0</td><td>  0.00000</td><td>  0.00000</td><td>  0.000000</td><td> 0.4800021</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td> 0.0000000</td><td>193.266420</td><td>0</td><td>  0.000000</td><td>  0.000000</td><td> 453.7901</td><td>109.19898</td><td>306.9316700</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_F10_S262_comb</th><td>0</td><td> 957.1716</td><td>164.868680</td><td>0</td><td>  0.00000</td><td>  0.00000</td><td>186.043240</td><td> 1.9899862</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td>16.6493430</td><td> 44.800915</td><td>0</td><td> 97.868370</td><td>476.949400</td><td> 552.9364</td><td>  0.00000</td><td>187.6943800</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_D04_S136_comb</th><td>0</td><td> 654.2250</td><td>  4.450005</td><td>0</td><td>  0.00000</td><td>107.05381</td><td>  0.000000</td><td> 1.6699631</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td> 0.0000000</td><td>  0.000000</td><td>0</td><td> 12.019779</td><td>  0.000000</td><td> 556.6555</td><td>394.08868</td><td>908.3677000</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_C06_S222_comb</th><td>0</td><td> 947.6324</td><td>  0.000000</td><td>0</td><td>  0.00000</td><td>  0.00000</td><td>107.859820</td><td> 1.4799789</td><td>0</td><td>16.140740</td><td>⋯</td><td>0</td><td> 0.0000000</td><td> 79.370580</td><td>0</td><td>  8.320006</td><td> 96.553055</td><td> 347.4576</td><td> 58.30068</td><td>171.0228600</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_C12_S228_comb</th><td>0</td><td>1294.9042</td><td> 74.661150</td><td>0</td><td>  0.00000</td><td>  0.00000</td><td>  0.000000</td><td> 0.0000000</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td> 0.0000000</td><td>184.405880</td><td>0</td><td> 64.327705</td><td> 54.580563</td><td>1089.3447</td><td>  0.00000</td><td> 16.6401100</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_H04_S184_comb</th><td>0</td><td> 671.7165</td><td>  0.000000</td><td>0</td><td>  0.00000</td><td> 16.86076</td><td>  0.000000</td><td> 0.0000000</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td> 0.0000000</td><td> 30.401253</td><td>0</td><td>  0.000000</td><td>  0.000000</td><td> 967.8898</td><td> 43.62107</td><td>104.4463900</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_C06_S126_comb</th><td>0</td><td> 846.6892</td><td> 10.820432</td><td>0</td><td>  0.00000</td><td>  0.00000</td><td>  3.520046</td><td> 0.0000000</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td> 0.5699973</td><td> 82.541466</td><td>0</td><td> 54.661186</td><td> 40.210880</td><td> 351.1685</td><td> 48.84011</td><td>323.1962000</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_D01_S37_comb</th><td>0</td><td> 939.7000</td><td> 67.280266</td><td>0</td><td> 66.31148</td><td>  0.00000</td><td> 81.838560</td><td> 0.0000000</td><td>0</td><td>37.640877</td><td>⋯</td><td>0</td><td> 0.0000000</td><td> 56.848724</td><td>0</td><td> 71.161750</td><td>  0.000000</td><td> 407.3541</td><td> 45.82843</td><td>  0.0000000</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_D09_S45_comb</th><td>0</td><td> 930.5939</td><td> 86.611840</td><td>0</td><td> 43.43185</td><td>  0.00000</td><td>165.902010</td><td> 0.0000000</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td> 2.4400303</td><td> 29.400120</td><td>0</td><td> 75.391945</td><td>  0.000000</td><td> 584.3332</td><td>  0.00000</td><td>339.3255000</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_E06_S150_comb</th><td>0</td><td> 989.4760</td><td> 25.369358</td><td>0</td><td>  0.00000</td><td> 21.50979</td><td>139.254240</td><td> 1.9600216</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td> 0.0000000</td><td>127.446660</td><td>0</td><td> 65.878970</td><td>  0.000000</td><td> 581.6204</td><td>185.17549</td><td>275.8725000</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_H10_S286_comb</th><td>0</td><td> 792.4280</td><td>  0.000000</td><td>0</td><td> 77.79264</td><td>  0.00000</td><td>151.593810</td><td> 0.0000000</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td> 0.0000000</td><td>155.596470</td><td>0</td><td>104.003006</td><td>  0.000000</td><td> 519.1849</td><td>  0.00000</td><td>223.2976700</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_A02_S98_comb</th><td>0</td><td> 236.4461</td><td>  0.000000</td><td>0</td><td>  0.00000</td><td>  0.00000</td><td>  0.000000</td><td> 0.0000000</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td> 0.3700007</td><td>  1.810008</td><td>0</td><td>  0.000000</td><td>  0.000000</td><td> 834.0169</td><td>191.48492</td><td>  0.0000000</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_D01_S229_comb</th><td>0</td><td> 339.5193</td><td>  0.000000</td><td>0</td><td> 88.75132</td><td>  0.00000</td><td>125.197820</td><td> 0.0000000</td><td>0</td><td> 6.970040</td><td>⋯</td><td>0</td><td> 0.7500249</td><td> 63.589504</td><td>0</td><td>167.358920</td><td>  0.000000</td><td> 627.2555</td><td>  0.00000</td><td>  4.2599607</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_G02_S266_comb</th><td>0</td><td> 209.8275</td><td>  0.000000</td><td>0</td><td>107.72918</td><td>  0.00000</td><td>  0.000000</td><td> 0.0000000</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td> 0.7600144</td><td>242.480480</td><td>0</td><td>  0.000000</td><td>160.476380</td><td> 516.6600</td><td>  0.00000</td><td>  1.5100173</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_B04_S112_comb</th><td>0</td><td>1445.9329</td><td>  0.000000</td><td>0</td><td>  0.00000</td><td> 86.65873</td><td>  0.000000</td><td> 0.7899636</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td> 0.2900001</td><td> 53.212067</td><td>0</td><td>186.696580</td><td>  0.000000</td><td>1366.3466</td><td>189.59450</td><td> 68.7292600</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_C09_S129_comb</th><td>0</td><td>1028.6747</td><td>  0.000000</td><td>0</td><td>  0.00000</td><td> 60.97938</td><td>  0.000000</td><td> 0.0000000</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td> 0.2299990</td><td>134.971760</td><td>0</td><td>  2.530031</td><td>  1.719979</td><td> 575.6229</td><td>404.24146</td><td>717.4115600</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_A12_S204_comb</th><td>0</td><td> 470.4119</td><td>  0.000000</td><td>0</td><td> 34.85908</td><td>  0.00000</td><td> 63.870586</td><td> 0.0000000</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td> 0.5500000</td><td>241.223590</td><td>0</td><td>147.414870</td><td>  0.000000</td><td> 276.5669</td><td> 34.83110</td><td> 62.6619450</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_F06_S162_comb</th><td>0</td><td>2064.6152</td><td>  0.000000</td><td>0</td><td>  0.00000</td><td>  0.00000</td><td>  0.000000</td><td> 1.6600178</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td> 0.5999981</td><td>113.009680</td><td>0</td><td>  1.330017</td><td>188.215790</td><td> 587.3067</td><td>499.63766</td><td>  2.8599942</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_B10_S22_comb</th><td>0</td><td>1163.5211</td><td>  0.000000</td><td>0</td><td> 71.86234</td><td>  0.00000</td><td>  0.000000</td><td> 0.0000000</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td> 0.6599968</td><td> 48.022000</td><td>0</td><td> 56.479060</td><td>  0.000000</td><td> 460.1014</td><td> 65.66888</td><td>158.0711200</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_B11_S215_comb</th><td>0</td><td> 614.6170</td><td>  5.380048</td><td>0</td><td>  0.00000</td><td>  0.00000</td><td> 69.878100</td><td> 3.0200050</td><td>0</td><td> 3.259993</td><td>⋯</td><td>0</td><td>15.1106610</td><td> 94.338524</td><td>0</td><td>134.150100</td><td>  0.000000</td><td> 690.5422</td><td> 23.28103</td><td> 50.9911540</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_C08_S32_comb</th><td>0</td><td> 273.4849</td><td>  0.000000</td><td>0</td><td>  0.00000</td><td>  0.00000</td><td>  0.000000</td><td>30.4909650</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td> 0.0000000</td><td>  0.000000</td><td>0</td><td> 98.709040</td><td>339.035030</td><td> 207.5085</td><td> 68.90955</td><td>316.0225800</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_H03_S183_comb</th><td>0</td><td>1821.2692</td><td>  0.000000</td><td>0</td><td>  0.00000</td><td>  0.00000</td><td>  0.000000</td><td> 0.5100024</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td> 0.0000000</td><td>167.518810</td><td>0</td><td>  0.000000</td><td>169.237430</td><td> 569.3246</td><td>562.22076</td><td>261.9369000</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_F09_S69_comb</th><td>0</td><td>1593.2993</td><td>  0.000000</td><td>0</td><td>  0.00000</td><td>  0.00000</td><td>105.186520</td><td> 0.0000000</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td> 0.0000000</td><td> 47.829273</td><td>0</td><td> 58.229706</td><td>  0.000000</td><td> 532.5183</td><td>118.63399</td><td>  0.7199636</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_G12_S180_comb</th><td>0</td><td> 400.5540</td><td>  0.000000</td><td>0</td><td>  0.00000</td><td>224.85526</td><td>  0.000000</td><td> 0.0000000</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td> 0.4199980</td><td>171.626140</td><td>0</td><td>  0.000000</td><td> 35.690680</td><td> 452.2495</td><td>  0.00000</td><td>497.6984600</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_C05_S221_comb</th><td>0</td><td>1712.1895</td><td>  0.000000</td><td>0</td><td>  0.00000</td><td>  0.00000</td><td>280.567200</td><td> 0.0000000</td><td>0</td><td> 8.780038</td><td>⋯</td><td>0</td><td> 1.8500241</td><td>  0.000000</td><td>0</td><td>  0.000000</td><td>  0.000000</td><td> 146.6964</td><td>  0.00000</td><td>  9.0699360</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_C12_S132_comb</th><td>0</td><td>1138.7333</td><td> 87.560690</td><td>0</td><td>  0.00000</td><td>  0.00000</td><td>  0.000000</td><td> 0.0000000</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td>39.6089360</td><td> 98.829666</td><td>0</td><td> 42.039246</td><td>  0.000000</td><td> 734.7581</td><td>213.79408</td><td>269.4271000</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_H08_S92_comb</th><td>0</td><td>1157.7600</td><td>  0.000000</td><td>0</td><td>396.78653</td><td>  0.00000</td><td>209.614290</td><td> 2.5999675</td><td>0</td><td> 0.000000</td><td>⋯</td><td>0</td><td> 0.8699854</td><td>  0.000000</td><td>0</td><td>157.861560</td><td> 17.220621</td><td> 570.2891</td><td>  0.00000</td><td>  0.8399643</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_G06_S78_comb</th><td>0</td><td> 785.9467</td><td>110.461480</td><td>0</td><td>  0.00000</td><td>  0.00000</td><td>  0.000000</td><td>74.4618600</td><td>0</td><td> 3.249978</td><td>⋯</td><td>0</td><td> 0.0000000</td><td> 92.681190</td><td>0</td><td>322.296700</td><td>  0.000000</td><td> 547.7706</td><td> 89.21099</td><td>388.0009500</td><td>0</td></tr>\n",
       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "A data.frame: 4484 × 21196\n",
       "\\begin{tabular}{r|lllllllllllllllllllll}\n",
       "  & C9orf152 & RPS11 & ELMO2 & CREB3L1 & PNMA1 & MMP2 & TMEM216 & TRAF3IP2-AS1 & LRRC37A5P & LOC653712 & ⋯ & MIR4691 & GPLD1 & RAB8A & RXFP2 & PCIF1 & PIK3IP1 & SNRPD2 & SLC39A6 & CTSC & AQP7\\\\\n",
       "  & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & ⋯ & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl>\\\\\n",
       "\\hline\n",
       "\tHN28\\_P15\\_D06\\_S330\\_comb & 0.000000 &  631.6435 &   0.0000000 & 0.000000 & 344.422900 &    0.000000 &   0.000000 &  2.3099935 & 0 & 0.000000 & ⋯ & 0 &  0.90999170 &   1.280023 & 0 & 156.2981300 &   0.000000 &   0.00000 &   0.000000 &   0.4400021 &  0.00000\\\\\n",
       "\tHN28\\_P6\\_G05\\_S173\\_comb & 0.000000 & 1566.5204 &   0.0000000 & 0.000000 & 393.053650 &    0.000000 &   0.000000 &  5.0599813 & 0 & 0.000000 & ⋯ & 0 &  0.00000000 &   0.000000 & 0 & 758.5674400 &   0.000000 & 329.32600 &   0.000000 &   2.1599727 &  0.00000\\\\\n",
       "\tHN26\\_P14\\_D11\\_S239\\_comb & 3.450036 & 1553.3533 &   0.0000000 & 0.000000 &  61.290012 &    0.000000 & 111.593990 &  0.9499934 & 0 & 0.000000 & ⋯ & 0 &  0.00000000 &   9.069936 & 0 & 160.2638200 &  71.308150 & 557.75635 &   0.000000 & 121.7380300 &  0.00000\\\\\n",
       "\tHN26\\_P14\\_H05\\_S281\\_comb & 0.000000 &    0.0000 & 369.6241800 & 0.000000 & 528.434900 &    0.000000 & 309.512400 & 87.4187850 & 0 & 0.000000 & ⋯ & 0 &  0.32999817 & 456.466000 & 0 &   0.0000000 & 764.020570 &   0.00000 &   0.000000 &   1.2399842 &  0.00000\\\\\n",
       "\tHN26\\_P25\\_H09\\_S189\\_comb & 0.000000 & 1768.1090 &   4.1899548 & 0.000000 &   1.460023 &    2.840043 &   0.000000 &  1.1799985 & 0 & 0.000000 & ⋯ & 0 &  0.49000233 &   2.409973 & 0 & 251.8193800 & 131.830900 & 204.93076 &   0.000000 &  96.6269300 &  0.00000\\\\\n",
       "\tHN26\\_P14\\_H06\\_S282\\_comb & 0.000000 & 1230.5189 &   0.0000000 & 0.000000 &  29.858847 &    0.000000 &   0.000000 &  0.7399703 & 0 & 0.000000 & ⋯ & 0 &  0.37000075 & 141.337750 & 0 &   9.1300410 & 118.180060 & 634.45154 &  35.299652 & 323.1500000 &  0.00000\\\\\n",
       "\tHN25\\_P25\\_C04\\_S316\\_comb & 0.000000 &  618.7001 &   0.0000000 & 0.000000 &   0.000000 &    0.000000 &   0.000000 &  9.9299760 & 0 & 0.000000 & ⋯ & 0 &  0.00000000 &   0.000000 & 0 &   0.0000000 &   0.000000 &   0.00000 &   0.000000 &  36.9394200 &  0.00000\\\\\n",
       "\tHN26\\_P25\\_A11\\_S107\\_comb & 0.000000 &  873.4031 &  96.6934740 & 0.000000 &  34.509090 &    0.000000 &   8.260041 & 90.2131600 & 0 & 0.000000 & ⋯ & 0 &  0.00000000 & 184.986190 & 0 &  61.1616500 &   0.000000 &   0.00000 &   0.000000 &   1.7899696 &  0.00000\\\\\n",
       "\tHN26\\_P25\\_C09\\_S129\\_comb & 0.000000 &  935.3653 &   0.0000000 & 0.000000 & 109.712340 &    0.000000 &   0.000000 &  0.6100025 & 0 & 0.000000 & ⋯ & 0 &  0.00000000 &   0.000000 & 0 &   0.0000000 &   0.000000 & 338.11690 &   0.000000 & 237.1645700 &  0.00000\\\\\n",
       "\tHNSCC26\\_P24\\_H05\\_S377\\_comb & 0.000000 & 2460.3984 &  28.9412700 & 0.000000 &   0.000000 &    0.000000 & 188.298250 &  5.7699710 & 0 & 0.000000 & ⋯ & 0 &  0.00000000 &   0.000000 & 0 &   0.0000000 &   0.000000 & 423.54205 &   0.000000 &   3.0300264 &  0.00000\\\\\n",
       "\tHN25\\_P5\\_E10\\_S58\\_comb & 0.000000 &  664.2445 &   0.0000000 & 0.000000 & 209.857990 &    0.000000 & 214.586610 &  1.9299666 & 0 & 0.000000 & ⋯ & 0 &  0.00000000 &  95.538680 & 0 & 157.4548200 &   8.780038 &   0.00000 & 273.878170 &  26.9199350 &  0.00000\\\\\n",
       "\tHN25\\_P24\\_B02\\_S110\\_comb & 0.000000 & 1829.2834 &  58.6376400 & 0.000000 &  23.410463 &    0.000000 &  22.729690 &  0.0000000 & 0 & 0.000000 & ⋯ & 0 &  0.00000000 & 116.819084 & 0 &  39.8295000 &   0.000000 & 136.93437 &  64.060280 & 158.0827800 &  0.00000\\\\\n",
       "\tHN25\\_P25\\_C01\\_S313\\_comb & 0.000000 & 1846.9614 &   0.0000000 & 0.000000 & 437.495120 &    0.000000 &   0.000000 &  1.8700005 & 0 & 0.000000 & ⋯ & 0 &  0.00000000 &   0.000000 & 0 &  76.0395500 &   0.000000 & 742.48975 &   0.000000 &   1.8900106 &  0.00000\\\\\n",
       "\tHN28\\_P15\\_G06\\_S366\\_comb & 0.000000 &  590.3367 &   0.0000000 & 0.000000 &   0.000000 &    0.000000 &   0.000000 & 61.2504920 & 0 & 0.000000 & ⋯ & 0 &  0.00000000 &   0.000000 & 0 &   0.0000000 &   0.000000 & 307.01956 &   0.000000 &   0.6200017 &  0.00000\\\\\n",
       "\tHN26\\_P6\\_B06\\_S18\\_comb & 0.000000 &    0.0000 &   0.0000000 & 0.000000 &   0.000000 &    0.000000 &   0.000000 &  1.6899600 & 0 & 0.000000 & ⋯ & 0 &  0.00000000 &   0.000000 & 0 &   0.0000000 &   0.000000 &   0.00000 &   0.000000 &   0.5600012 &  0.00000\\\\\n",
       "\tHN25\\_P5\\_C05\\_S29\\_comb & 0.000000 &  375.4308 &  94.4108660 & 0.000000 &   0.000000 & 1109.491700 &   0.000000 &  1.2300161 & 0 & 0.000000 & ⋯ & 0 &  0.00000000 &  43.911760 & 0 &   0.0000000 &   0.000000 & 155.76874 &   0.000000 & 672.6149000 &  0.00000\\\\\n",
       "\tHN28\\_P6\\_D09\\_S141\\_comb & 0.000000 & 2414.9312 &   0.0000000 & 0.000000 &   0.000000 &    0.000000 &   0.000000 &  7.5400150 & 0 & 0.000000 & ⋯ & 0 &  0.00000000 &   0.000000 & 0 &   0.0000000 &   0.000000 &   0.00000 &   0.000000 &   5.2099986 &  0.00000\\\\\n",
       "\tHN26\\_P5\\_H01\\_S85\\_comb & 0.000000 & 1616.3568 &   0.5800027 & 6.390047 &   0.000000 &    0.000000 &   0.000000 &  0.0000000 & 0 & 0.000000 & ⋯ & 0 &  0.41999800 &   0.000000 & 0 &   0.7899636 &   0.000000 & 549.12540 &   0.000000 &  65.8789700 &  0.00000\\\\\n",
       "\tHN26\\_P13\\_D07\\_S139\\_comb & 0.000000 &  853.7249 &   0.0000000 & 0.000000 &   0.000000 &    0.000000 &   0.000000 & 10.9101010 & 0 & 0.000000 & ⋯ & 0 &  0.00000000 &   0.000000 & 0 &   0.0000000 &   0.000000 &   0.00000 &   0.000000 &   1.8500241 &  0.00000\\\\\n",
       "\tHN26\\_P5\\_E06\\_S54\\_comb & 0.000000 &  956.7695 &   1.1000025 & 0.000000 &   0.000000 &    0.000000 &   0.000000 &  3.5100217 & 0 & 0.000000 & ⋯ & 0 &  1.63999140 &  48.628414 & 0 &   0.0000000 &   0.000000 & 444.43436 &  62.737534 &   1.6199994 & 12.16065\\\\\n",
       "\tHN26\\_P26\\_H05\\_S377\\_comb & 0.000000 & 1412.8108 &   0.0000000 & 0.000000 &  30.000000 &    0.000000 &   0.000000 &  0.6599968 & 0 & 0.000000 & ⋯ & 0 &  0.49000233 & 103.380450 & 0 & 153.5545500 &   0.000000 & 432.62100 &   6.879942 &  68.2776260 &  0.00000\\\\\n",
       "\tHNSCC26\\_P24\\_F12\\_S360\\_comb & 0.000000 & 1732.4820 &   0.0000000 & 0.000000 &   0.000000 &    0.000000 & 450.841920 &  2.0899644 & 0 & 0.000000 & ⋯ & 0 & 17.49939700 &   3.340012 & 0 &   0.0000000 &   0.000000 & 583.79785 & 140.793260 &  10.7901480 &  0.00000\\\\\n",
       "\tHNSCC26\\_P24\\_F03\\_S351\\_comb & 0.000000 & 1171.4379 & 123.3827300 & 0.000000 &   0.000000 &    0.000000 &   0.000000 &  0.0000000 & 0 & 0.000000 & ⋯ & 0 &  1.23001610 &  81.577934 & 0 & 357.9403400 &   0.000000 & 359.01306 &  60.201410 & 172.1304200 &  0.00000\\\\\n",
       "\tHN26\\_P6\\_D08\\_S44\\_comb & 0.000000 &  306.2295 &   0.0000000 & 0.000000 &   0.000000 &    0.000000 &   0.000000 &  4.1399794 & 0 & 2.360011 & ⋯ & 0 &  0.08999878 & 117.612700 & 0 &   0.0000000 & 573.677700 &  73.17789 & 259.180100 &   2.5600307 &  0.00000\\\\\n",
       "\tHN25\\_P5\\_E12\\_S60\\_comb & 0.000000 &  346.3937 & 112.7796860 & 0.000000 &   3.870021 &    0.000000 & 153.826860 &  0.0000000 & 0 & 0.000000 & ⋯ & 0 &  0.83996430 & 109.978165 & 0 &   0.0000000 &   0.000000 & 220.74060 & 172.927490 &   0.8100261 &  0.00000\\\\\n",
       "\tHNSCC26\\_P24\\_C01\\_S313\\_comb & 0.000000 & 1572.8711 &  33.7687150 & 0.000000 &  70.411400 &    0.000000 &   0.000000 & 20.6099360 & 0 & 0.000000 & ⋯ & 0 & 54.01012000 &   0.000000 & 0 &  95.6631200 &  86.277590 & 674.13070 &  27.310974 & 418.6416000 &  0.00000\\\\\n",
       "\tHN25\\_P5\\_F01\\_S61\\_comb & 0.000000 &  820.4952 &   0.0000000 & 0.000000 & 530.266700 &    0.000000 &   0.000000 &  2.2799952 & 0 & 0.000000 & ⋯ & 0 &  1.12997230 &   0.000000 & 0 &   0.0000000 &   0.000000 &   0.00000 &   0.000000 &   1.5700091 &  0.00000\\\\\n",
       "\tHN26\\_P5\\_D12\\_S48\\_comb & 0.000000 & 1070.5334 &   0.0000000 & 0.000000 &   0.000000 &    0.000000 &   0.000000 &  0.0000000 & 0 & 0.000000 & ⋯ & 0 &  0.00000000 &   0.000000 & 0 &  12.3503895 &   0.000000 &   0.00000 &   0.000000 &  11.4905140 &  0.00000\\\\\n",
       "\tHN25\\_P25\\_C11\\_S323\\_comb & 0.000000 & 1415.6737 & 225.6379500 & 0.000000 &   0.000000 &  211.525360 &   0.000000 &  0.0000000 & 0 & 0.000000 & ⋯ & 0 &  0.90001410 &   0.000000 & 0 & 172.3957200 &   0.000000 & 199.14041 &   0.000000 &   3.3800175 &  0.00000\\\\\n",
       "\tHN25\\_P25\\_B12\\_S312\\_comb & 0.000000 & 1473.4371 &   0.0000000 & 0.000000 &   0.000000 &    4.119999 &   0.000000 &  0.4800021 & 0 & 0.000000 & ⋯ & 0 &  0.35000166 &  75.771600 & 0 &  14.1998820 &   0.000000 & 418.52280 &  28.989887 &  11.7407250 &  0.00000\\\\\n",
       "\t⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋱ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮\\\\\n",
       "\tHNSCC17\\_P4\\_A08\\_S104\\_comb & 0 &  469.1814 &   0.000000 & 0 &   0.00000 &   0.00000 &   0.000000 &  0.0000000 & 0 &  0.000000 & ⋯ & 0 &  0.0000000 &  63.737576 & 0 &  54.620860 &  53.899296 &  920.3489 & 311.53415 & 107.6965400 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_E10\\_S154\\_comb & 0 & 1168.4935 &   0.000000 & 0 &   0.00000 &   0.00000 &   0.000000 &  0.7299994 & 0 &  0.000000 & ⋯ & 0 &  0.7800211 & 256.820950 & 0 &   0.000000 &  89.721180 &  494.7160 & 131.82108 &   2.2299626 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_E02\\_S146\\_comb & 0 &  825.4607 &   0.000000 & 0 &   0.00000 &   0.00000 &   0.000000 &  0.4800021 & 0 &  0.000000 & ⋯ & 0 &  0.0000000 & 193.266420 & 0 &   0.000000 &   0.000000 &  453.7901 & 109.19898 & 306.9316700 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_F10\\_S262\\_comb & 0 &  957.1716 & 164.868680 & 0 &   0.00000 &   0.00000 & 186.043240 &  1.9899862 & 0 &  0.000000 & ⋯ & 0 & 16.6493430 &  44.800915 & 0 &  97.868370 & 476.949400 &  552.9364 &   0.00000 & 187.6943800 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_D04\\_S136\\_comb & 0 &  654.2250 &   4.450005 & 0 &   0.00000 & 107.05381 &   0.000000 &  1.6699631 & 0 &  0.000000 & ⋯ & 0 &  0.0000000 &   0.000000 & 0 &  12.019779 &   0.000000 &  556.6555 & 394.08868 & 908.3677000 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_C06\\_S222\\_comb & 0 &  947.6324 &   0.000000 & 0 &   0.00000 &   0.00000 & 107.859820 &  1.4799789 & 0 & 16.140740 & ⋯ & 0 &  0.0000000 &  79.370580 & 0 &   8.320006 &  96.553055 &  347.4576 &  58.30068 & 171.0228600 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_C12\\_S228\\_comb & 0 & 1294.9042 &  74.661150 & 0 &   0.00000 &   0.00000 &   0.000000 &  0.0000000 & 0 &  0.000000 & ⋯ & 0 &  0.0000000 & 184.405880 & 0 &  64.327705 &  54.580563 & 1089.3447 &   0.00000 &  16.6401100 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_H04\\_S184\\_comb & 0 &  671.7165 &   0.000000 & 0 &   0.00000 &  16.86076 &   0.000000 &  0.0000000 & 0 &  0.000000 & ⋯ & 0 &  0.0000000 &  30.401253 & 0 &   0.000000 &   0.000000 &  967.8898 &  43.62107 & 104.4463900 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_C06\\_S126\\_comb & 0 &  846.6892 &  10.820432 & 0 &   0.00000 &   0.00000 &   3.520046 &  0.0000000 & 0 &  0.000000 & ⋯ & 0 &  0.5699973 &  82.541466 & 0 &  54.661186 &  40.210880 &  351.1685 &  48.84011 & 323.1962000 & 0\\\\\n",
       "\tHNSCC20\\_P3\\_D01\\_S37\\_comb & 0 &  939.7000 &  67.280266 & 0 &  66.31148 &   0.00000 &  81.838560 &  0.0000000 & 0 & 37.640877 & ⋯ & 0 &  0.0000000 &  56.848724 & 0 &  71.161750 &   0.000000 &  407.3541 &  45.82843 &   0.0000000 & 0\\\\\n",
       "\tHNSCC20\\_P3\\_D09\\_S45\\_comb & 0 &  930.5939 &  86.611840 & 0 &  43.43185 &   0.00000 & 165.902010 &  0.0000000 & 0 &  0.000000 & ⋯ & 0 &  2.4400303 &  29.400120 & 0 &  75.391945 &   0.000000 &  584.3332 &   0.00000 & 339.3255000 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_E06\\_S150\\_comb & 0 &  989.4760 &  25.369358 & 0 &   0.00000 &  21.50979 & 139.254240 &  1.9600216 & 0 &  0.000000 & ⋯ & 0 &  0.0000000 & 127.446660 & 0 &  65.878970 &   0.000000 &  581.6204 & 185.17549 & 275.8725000 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_H10\\_S286\\_comb & 0 &  792.4280 &   0.000000 & 0 &  77.79264 &   0.00000 & 151.593810 &  0.0000000 & 0 &  0.000000 & ⋯ & 0 &  0.0000000 & 155.596470 & 0 & 104.003006 &   0.000000 &  519.1849 &   0.00000 & 223.2976700 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_A02\\_S98\\_comb & 0 &  236.4461 &   0.000000 & 0 &   0.00000 &   0.00000 &   0.000000 &  0.0000000 & 0 &  0.000000 & ⋯ & 0 &  0.3700007 &   1.810008 & 0 &   0.000000 &   0.000000 &  834.0169 & 191.48492 &   0.0000000 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_D01\\_S229\\_comb & 0 &  339.5193 &   0.000000 & 0 &  88.75132 &   0.00000 & 125.197820 &  0.0000000 & 0 &  6.970040 & ⋯ & 0 &  0.7500249 &  63.589504 & 0 & 167.358920 &   0.000000 &  627.2555 &   0.00000 &   4.2599607 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_G02\\_S266\\_comb & 0 &  209.8275 &   0.000000 & 0 & 107.72918 &   0.00000 &   0.000000 &  0.0000000 & 0 &  0.000000 & ⋯ & 0 &  0.7600144 & 242.480480 & 0 &   0.000000 & 160.476380 &  516.6600 &   0.00000 &   1.5100173 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_B04\\_S112\\_comb & 0 & 1445.9329 &   0.000000 & 0 &   0.00000 &  86.65873 &   0.000000 &  0.7899636 & 0 &  0.000000 & ⋯ & 0 &  0.2900001 &  53.212067 & 0 & 186.696580 &   0.000000 & 1366.3466 & 189.59450 &  68.7292600 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_C09\\_S129\\_comb & 0 & 1028.6747 &   0.000000 & 0 &   0.00000 &  60.97938 &   0.000000 &  0.0000000 & 0 &  0.000000 & ⋯ & 0 &  0.2299990 & 134.971760 & 0 &   2.530031 &   1.719979 &  575.6229 & 404.24146 & 717.4115600 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_A12\\_S204\\_comb & 0 &  470.4119 &   0.000000 & 0 &  34.85908 &   0.00000 &  63.870586 &  0.0000000 & 0 &  0.000000 & ⋯ & 0 &  0.5500000 & 241.223590 & 0 & 147.414870 &   0.000000 &  276.5669 &  34.83110 &  62.6619450 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_F06\\_S162\\_comb & 0 & 2064.6152 &   0.000000 & 0 &   0.00000 &   0.00000 &   0.000000 &  1.6600178 & 0 &  0.000000 & ⋯ & 0 &  0.5999981 & 113.009680 & 0 &   1.330017 & 188.215790 &  587.3067 & 499.63766 &   2.8599942 & 0\\\\\n",
       "\tHNSCC20\\_P3\\_B10\\_S22\\_comb & 0 & 1163.5211 &   0.000000 & 0 &  71.86234 &   0.00000 &   0.000000 &  0.0000000 & 0 &  0.000000 & ⋯ & 0 &  0.6599968 &  48.022000 & 0 &  56.479060 &   0.000000 &  460.1014 &  65.66888 & 158.0711200 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_B11\\_S215\\_comb & 0 &  614.6170 &   5.380048 & 0 &   0.00000 &   0.00000 &  69.878100 &  3.0200050 & 0 &  3.259993 & ⋯ & 0 & 15.1106610 &  94.338524 & 0 & 134.150100 &   0.000000 &  690.5422 &  23.28103 &  50.9911540 & 0\\\\\n",
       "\tHNSCC20\\_P3\\_C08\\_S32\\_comb & 0 &  273.4849 &   0.000000 & 0 &   0.00000 &   0.00000 &   0.000000 & 30.4909650 & 0 &  0.000000 & ⋯ & 0 &  0.0000000 &   0.000000 & 0 &  98.709040 & 339.035030 &  207.5085 &  68.90955 & 316.0225800 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_H03\\_S183\\_comb & 0 & 1821.2692 &   0.000000 & 0 &   0.00000 &   0.00000 &   0.000000 &  0.5100024 & 0 &  0.000000 & ⋯ & 0 &  0.0000000 & 167.518810 & 0 &   0.000000 & 169.237430 &  569.3246 & 562.22076 & 261.9369000 & 0\\\\\n",
       "\tHNSCC20\\_P3\\_F09\\_S69\\_comb & 0 & 1593.2993 &   0.000000 & 0 &   0.00000 &   0.00000 & 105.186520 &  0.0000000 & 0 &  0.000000 & ⋯ & 0 &  0.0000000 &  47.829273 & 0 &  58.229706 &   0.000000 &  532.5183 & 118.63399 &   0.7199636 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_G12\\_S180\\_comb & 0 &  400.5540 &   0.000000 & 0 &   0.00000 & 224.85526 &   0.000000 &  0.0000000 & 0 &  0.000000 & ⋯ & 0 &  0.4199980 & 171.626140 & 0 &   0.000000 &  35.690680 &  452.2495 &   0.00000 & 497.6984600 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_C05\\_S221\\_comb & 0 & 1712.1895 &   0.000000 & 0 &   0.00000 &   0.00000 & 280.567200 &  0.0000000 & 0 &  8.780038 & ⋯ & 0 &  1.8500241 &   0.000000 & 0 &   0.000000 &   0.000000 &  146.6964 &   0.00000 &   9.0699360 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_C12\\_S132\\_comb & 0 & 1138.7333 &  87.560690 & 0 &   0.00000 &   0.00000 &   0.000000 &  0.0000000 & 0 &  0.000000 & ⋯ & 0 & 39.6089360 &  98.829666 & 0 &  42.039246 &   0.000000 &  734.7581 & 213.79408 & 269.4271000 & 0\\\\\n",
       "\tHNSCC20\\_P3\\_H08\\_S92\\_comb & 0 & 1157.7600 &   0.000000 & 0 & 396.78653 &   0.00000 & 209.614290 &  2.5999675 & 0 &  0.000000 & ⋯ & 0 &  0.8699854 &   0.000000 & 0 & 157.861560 &  17.220621 &  570.2891 &   0.00000 &   0.8399643 & 0\\\\\n",
       "\tHNSCC20\\_P3\\_G06\\_S78\\_comb & 0 &  785.9467 & 110.461480 & 0 &   0.00000 &   0.00000 &   0.000000 & 74.4618600 & 0 &  3.249978 & ⋯ & 0 &  0.0000000 &  92.681190 & 0 & 322.296700 &   0.000000 &  547.7706 &  89.21099 & 388.0009500 & 0\\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "A data.frame: 4484 × 21196\n",
       "\n",
       "| <!--/--> | C9orf152 &lt;dbl&gt; | RPS11 &lt;dbl&gt; | ELMO2 &lt;dbl&gt; | CREB3L1 &lt;dbl&gt; | PNMA1 &lt;dbl&gt; | MMP2 &lt;dbl&gt; | TMEM216 &lt;dbl&gt; | TRAF3IP2-AS1 &lt;dbl&gt; | LRRC37A5P &lt;dbl&gt; | LOC653712 &lt;dbl&gt; | ⋯ ⋯ | MIR4691 &lt;dbl&gt; | GPLD1 &lt;dbl&gt; | RAB8A &lt;dbl&gt; | RXFP2 &lt;dbl&gt; | PCIF1 &lt;dbl&gt; | PIK3IP1 &lt;dbl&gt; | SNRPD2 &lt;dbl&gt; | SLC39A6 &lt;dbl&gt; | CTSC &lt;dbl&gt; | AQP7 &lt;dbl&gt; |\n",
       "|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|\n",
       "| HN28_P15_D06_S330_comb | 0.000000 |  631.6435 |   0.0000000 | 0.000000 | 344.422900 |    0.000000 |   0.000000 |  2.3099935 | 0 | 0.000000 | ⋯ | 0 |  0.90999170 |   1.280023 | 0 | 156.2981300 |   0.000000 |   0.00000 |   0.000000 |   0.4400021 |  0.00000 |\n",
       "| HN28_P6_G05_S173_comb | 0.000000 | 1566.5204 |   0.0000000 | 0.000000 | 393.053650 |    0.000000 |   0.000000 |  5.0599813 | 0 | 0.000000 | ⋯ | 0 |  0.00000000 |   0.000000 | 0 | 758.5674400 |   0.000000 | 329.32600 |   0.000000 |   2.1599727 |  0.00000 |\n",
       "| HN26_P14_D11_S239_comb | 3.450036 | 1553.3533 |   0.0000000 | 0.000000 |  61.290012 |    0.000000 | 111.593990 |  0.9499934 | 0 | 0.000000 | ⋯ | 0 |  0.00000000 |   9.069936 | 0 | 160.2638200 |  71.308150 | 557.75635 |   0.000000 | 121.7380300 |  0.00000 |\n",
       "| HN26_P14_H05_S281_comb | 0.000000 |    0.0000 | 369.6241800 | 0.000000 | 528.434900 |    0.000000 | 309.512400 | 87.4187850 | 0 | 0.000000 | ⋯ | 0 |  0.32999817 | 456.466000 | 0 |   0.0000000 | 764.020570 |   0.00000 |   0.000000 |   1.2399842 |  0.00000 |\n",
       "| HN26_P25_H09_S189_comb | 0.000000 | 1768.1090 |   4.1899548 | 0.000000 |   1.460023 |    2.840043 |   0.000000 |  1.1799985 | 0 | 0.000000 | ⋯ | 0 |  0.49000233 |   2.409973 | 0 | 251.8193800 | 131.830900 | 204.93076 |   0.000000 |  96.6269300 |  0.00000 |\n",
       "| HN26_P14_H06_S282_comb | 0.000000 | 1230.5189 |   0.0000000 | 0.000000 |  29.858847 |    0.000000 |   0.000000 |  0.7399703 | 0 | 0.000000 | ⋯ | 0 |  0.37000075 | 141.337750 | 0 |   9.1300410 | 118.180060 | 634.45154 |  35.299652 | 323.1500000 |  0.00000 |\n",
       "| HN25_P25_C04_S316_comb | 0.000000 |  618.7001 |   0.0000000 | 0.000000 |   0.000000 |    0.000000 |   0.000000 |  9.9299760 | 0 | 0.000000 | ⋯ | 0 |  0.00000000 |   0.000000 | 0 |   0.0000000 |   0.000000 |   0.00000 |   0.000000 |  36.9394200 |  0.00000 |\n",
       "| HN26_P25_A11_S107_comb | 0.000000 |  873.4031 |  96.6934740 | 0.000000 |  34.509090 |    0.000000 |   8.260041 | 90.2131600 | 0 | 0.000000 | ⋯ | 0 |  0.00000000 | 184.986190 | 0 |  61.1616500 |   0.000000 |   0.00000 |   0.000000 |   1.7899696 |  0.00000 |\n",
       "| HN26_P25_C09_S129_comb | 0.000000 |  935.3653 |   0.0000000 | 0.000000 | 109.712340 |    0.000000 |   0.000000 |  0.6100025 | 0 | 0.000000 | ⋯ | 0 |  0.00000000 |   0.000000 | 0 |   0.0000000 |   0.000000 | 338.11690 |   0.000000 | 237.1645700 |  0.00000 |\n",
       "| HNSCC26_P24_H05_S377_comb | 0.000000 | 2460.3984 |  28.9412700 | 0.000000 |   0.000000 |    0.000000 | 188.298250 |  5.7699710 | 0 | 0.000000 | ⋯ | 0 |  0.00000000 |   0.000000 | 0 |   0.0000000 |   0.000000 | 423.54205 |   0.000000 |   3.0300264 |  0.00000 |\n",
       "| HN25_P5_E10_S58_comb | 0.000000 |  664.2445 |   0.0000000 | 0.000000 | 209.857990 |    0.000000 | 214.586610 |  1.9299666 | 0 | 0.000000 | ⋯ | 0 |  0.00000000 |  95.538680 | 0 | 157.4548200 |   8.780038 |   0.00000 | 273.878170 |  26.9199350 |  0.00000 |\n",
       "| HN25_P24_B02_S110_comb | 0.000000 | 1829.2834 |  58.6376400 | 0.000000 |  23.410463 |    0.000000 |  22.729690 |  0.0000000 | 0 | 0.000000 | ⋯ | 0 |  0.00000000 | 116.819084 | 0 |  39.8295000 |   0.000000 | 136.93437 |  64.060280 | 158.0827800 |  0.00000 |\n",
       "| HN25_P25_C01_S313_comb | 0.000000 | 1846.9614 |   0.0000000 | 0.000000 | 437.495120 |    0.000000 |   0.000000 |  1.8700005 | 0 | 0.000000 | ⋯ | 0 |  0.00000000 |   0.000000 | 0 |  76.0395500 |   0.000000 | 742.48975 |   0.000000 |   1.8900106 |  0.00000 |\n",
       "| HN28_P15_G06_S366_comb | 0.000000 |  590.3367 |   0.0000000 | 0.000000 |   0.000000 |    0.000000 |   0.000000 | 61.2504920 | 0 | 0.000000 | ⋯ | 0 |  0.00000000 |   0.000000 | 0 |   0.0000000 |   0.000000 | 307.01956 |   0.000000 |   0.6200017 |  0.00000 |\n",
       "| HN26_P6_B06_S18_comb | 0.000000 |    0.0000 |   0.0000000 | 0.000000 |   0.000000 |    0.000000 |   0.000000 |  1.6899600 | 0 | 0.000000 | ⋯ | 0 |  0.00000000 |   0.000000 | 0 |   0.0000000 |   0.000000 |   0.00000 |   0.000000 |   0.5600012 |  0.00000 |\n",
       "| HN25_P5_C05_S29_comb | 0.000000 |  375.4308 |  94.4108660 | 0.000000 |   0.000000 | 1109.491700 |   0.000000 |  1.2300161 | 0 | 0.000000 | ⋯ | 0 |  0.00000000 |  43.911760 | 0 |   0.0000000 |   0.000000 | 155.76874 |   0.000000 | 672.6149000 |  0.00000 |\n",
       "| HN28_P6_D09_S141_comb | 0.000000 | 2414.9312 |   0.0000000 | 0.000000 |   0.000000 |    0.000000 |   0.000000 |  7.5400150 | 0 | 0.000000 | ⋯ | 0 |  0.00000000 |   0.000000 | 0 |   0.0000000 |   0.000000 |   0.00000 |   0.000000 |   5.2099986 |  0.00000 |\n",
       "| HN26_P5_H01_S85_comb | 0.000000 | 1616.3568 |   0.5800027 | 6.390047 |   0.000000 |    0.000000 |   0.000000 |  0.0000000 | 0 | 0.000000 | ⋯ | 0 |  0.41999800 |   0.000000 | 0 |   0.7899636 |   0.000000 | 549.12540 |   0.000000 |  65.8789700 |  0.00000 |\n",
       "| HN26_P13_D07_S139_comb | 0.000000 |  853.7249 |   0.0000000 | 0.000000 |   0.000000 |    0.000000 |   0.000000 | 10.9101010 | 0 | 0.000000 | ⋯ | 0 |  0.00000000 |   0.000000 | 0 |   0.0000000 |   0.000000 |   0.00000 |   0.000000 |   1.8500241 |  0.00000 |\n",
       "| HN26_P5_E06_S54_comb | 0.000000 |  956.7695 |   1.1000025 | 0.000000 |   0.000000 |    0.000000 |   0.000000 |  3.5100217 | 0 | 0.000000 | ⋯ | 0 |  1.63999140 |  48.628414 | 0 |   0.0000000 |   0.000000 | 444.43436 |  62.737534 |   1.6199994 | 12.16065 |\n",
       "| HN26_P26_H05_S377_comb | 0.000000 | 1412.8108 |   0.0000000 | 0.000000 |  30.000000 |    0.000000 |   0.000000 |  0.6599968 | 0 | 0.000000 | ⋯ | 0 |  0.49000233 | 103.380450 | 0 | 153.5545500 |   0.000000 | 432.62100 |   6.879942 |  68.2776260 |  0.00000 |\n",
       "| HNSCC26_P24_F12_S360_comb | 0.000000 | 1732.4820 |   0.0000000 | 0.000000 |   0.000000 |    0.000000 | 450.841920 |  2.0899644 | 0 | 0.000000 | ⋯ | 0 | 17.49939700 |   3.340012 | 0 |   0.0000000 |   0.000000 | 583.79785 | 140.793260 |  10.7901480 |  0.00000 |\n",
       "| HNSCC26_P24_F03_S351_comb | 0.000000 | 1171.4379 | 123.3827300 | 0.000000 |   0.000000 |    0.000000 |   0.000000 |  0.0000000 | 0 | 0.000000 | ⋯ | 0 |  1.23001610 |  81.577934 | 0 | 357.9403400 |   0.000000 | 359.01306 |  60.201410 | 172.1304200 |  0.00000 |\n",
       "| HN26_P6_D08_S44_comb | 0.000000 |  306.2295 |   0.0000000 | 0.000000 |   0.000000 |    0.000000 |   0.000000 |  4.1399794 | 0 | 2.360011 | ⋯ | 0 |  0.08999878 | 117.612700 | 0 |   0.0000000 | 573.677700 |  73.17789 | 259.180100 |   2.5600307 |  0.00000 |\n",
       "| HN25_P5_E12_S60_comb | 0.000000 |  346.3937 | 112.7796860 | 0.000000 |   3.870021 |    0.000000 | 153.826860 |  0.0000000 | 0 | 0.000000 | ⋯ | 0 |  0.83996430 | 109.978165 | 0 |   0.0000000 |   0.000000 | 220.74060 | 172.927490 |   0.8100261 |  0.00000 |\n",
       "| HNSCC26_P24_C01_S313_comb | 0.000000 | 1572.8711 |  33.7687150 | 0.000000 |  70.411400 |    0.000000 |   0.000000 | 20.6099360 | 0 | 0.000000 | ⋯ | 0 | 54.01012000 |   0.000000 | 0 |  95.6631200 |  86.277590 | 674.13070 |  27.310974 | 418.6416000 |  0.00000 |\n",
       "| HN25_P5_F01_S61_comb | 0.000000 |  820.4952 |   0.0000000 | 0.000000 | 530.266700 |    0.000000 |   0.000000 |  2.2799952 | 0 | 0.000000 | ⋯ | 0 |  1.12997230 |   0.000000 | 0 |   0.0000000 |   0.000000 |   0.00000 |   0.000000 |   1.5700091 |  0.00000 |\n",
       "| HN26_P5_D12_S48_comb | 0.000000 | 1070.5334 |   0.0000000 | 0.000000 |   0.000000 |    0.000000 |   0.000000 |  0.0000000 | 0 | 0.000000 | ⋯ | 0 |  0.00000000 |   0.000000 | 0 |  12.3503895 |   0.000000 |   0.00000 |   0.000000 |  11.4905140 |  0.00000 |\n",
       "| HN25_P25_C11_S323_comb | 0.000000 | 1415.6737 | 225.6379500 | 0.000000 |   0.000000 |  211.525360 |   0.000000 |  0.0000000 | 0 | 0.000000 | ⋯ | 0 |  0.90001410 |   0.000000 | 0 | 172.3957200 |   0.000000 | 199.14041 |   0.000000 |   3.3800175 |  0.00000 |\n",
       "| HN25_P25_B12_S312_comb | 0.000000 | 1473.4371 |   0.0000000 | 0.000000 |   0.000000 |    4.119999 |   0.000000 |  0.4800021 | 0 | 0.000000 | ⋯ | 0 |  0.35000166 |  75.771600 | 0 |  14.1998820 |   0.000000 | 418.52280 |  28.989887 |  11.7407250 |  0.00000 |\n",
       "| ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋱ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ |\n",
       "| HNSCC17_P4_A08_S104_comb | 0 |  469.1814 |   0.000000 | 0 |   0.00000 |   0.00000 |   0.000000 |  0.0000000 | 0 |  0.000000 | ⋯ | 0 |  0.0000000 |  63.737576 | 0 |  54.620860 |  53.899296 |  920.3489 | 311.53415 | 107.6965400 | 0 |\n",
       "| HNSCC17_P4_E10_S154_comb | 0 | 1168.4935 |   0.000000 | 0 |   0.00000 |   0.00000 |   0.000000 |  0.7299994 | 0 |  0.000000 | ⋯ | 0 |  0.7800211 | 256.820950 | 0 |   0.000000 |  89.721180 |  494.7160 | 131.82108 |   2.2299626 | 0 |\n",
       "| HNSCC17_P4_E02_S146_comb | 0 |  825.4607 |   0.000000 | 0 |   0.00000 |   0.00000 |   0.000000 |  0.4800021 | 0 |  0.000000 | ⋯ | 0 |  0.0000000 | 193.266420 | 0 |   0.000000 |   0.000000 |  453.7901 | 109.19898 | 306.9316700 | 0 |\n",
       "| HNSCC20_P13_F10_S262_comb | 0 |  957.1716 | 164.868680 | 0 |   0.00000 |   0.00000 | 186.043240 |  1.9899862 | 0 |  0.000000 | ⋯ | 0 | 16.6493430 |  44.800915 | 0 |  97.868370 | 476.949400 |  552.9364 |   0.00000 | 187.6943800 | 0 |\n",
       "| HNSCC17_P4_D04_S136_comb | 0 |  654.2250 |   4.450005 | 0 |   0.00000 | 107.05381 |   0.000000 |  1.6699631 | 0 |  0.000000 | ⋯ | 0 |  0.0000000 |   0.000000 | 0 |  12.019779 |   0.000000 |  556.6555 | 394.08868 | 908.3677000 | 0 |\n",
       "| HNSCC20_P13_C06_S222_comb | 0 |  947.6324 |   0.000000 | 0 |   0.00000 |   0.00000 | 107.859820 |  1.4799789 | 0 | 16.140740 | ⋯ | 0 |  0.0000000 |  79.370580 | 0 |   8.320006 |  96.553055 |  347.4576 |  58.30068 | 171.0228600 | 0 |\n",
       "| HNSCC20_P13_C12_S228_comb | 0 | 1294.9042 |  74.661150 | 0 |   0.00000 |   0.00000 |   0.000000 |  0.0000000 | 0 |  0.000000 | ⋯ | 0 |  0.0000000 | 184.405880 | 0 |  64.327705 |  54.580563 | 1089.3447 |   0.00000 |  16.6401100 | 0 |\n",
       "| HNSCC17_P4_H04_S184_comb | 0 |  671.7165 |   0.000000 | 0 |   0.00000 |  16.86076 |   0.000000 |  0.0000000 | 0 |  0.000000 | ⋯ | 0 |  0.0000000 |  30.401253 | 0 |   0.000000 |   0.000000 |  967.8898 |  43.62107 | 104.4463900 | 0 |\n",
       "| HNSCC17_P4_C06_S126_comb | 0 |  846.6892 |  10.820432 | 0 |   0.00000 |   0.00000 |   3.520046 |  0.0000000 | 0 |  0.000000 | ⋯ | 0 |  0.5699973 |  82.541466 | 0 |  54.661186 |  40.210880 |  351.1685 |  48.84011 | 323.1962000 | 0 |\n",
       "| HNSCC20_P3_D01_S37_comb | 0 |  939.7000 |  67.280266 | 0 |  66.31148 |   0.00000 |  81.838560 |  0.0000000 | 0 | 37.640877 | ⋯ | 0 |  0.0000000 |  56.848724 | 0 |  71.161750 |   0.000000 |  407.3541 |  45.82843 |   0.0000000 | 0 |\n",
       "| HNSCC20_P3_D09_S45_comb | 0 |  930.5939 |  86.611840 | 0 |  43.43185 |   0.00000 | 165.902010 |  0.0000000 | 0 |  0.000000 | ⋯ | 0 |  2.4400303 |  29.400120 | 0 |  75.391945 |   0.000000 |  584.3332 |   0.00000 | 339.3255000 | 0 |\n",
       "| HNSCC17_P4_E06_S150_comb | 0 |  989.4760 |  25.369358 | 0 |   0.00000 |  21.50979 | 139.254240 |  1.9600216 | 0 |  0.000000 | ⋯ | 0 |  0.0000000 | 127.446660 | 0 |  65.878970 |   0.000000 |  581.6204 | 185.17549 | 275.8725000 | 0 |\n",
       "| HNSCC20_P13_H10_S286_comb | 0 |  792.4280 |   0.000000 | 0 |  77.79264 |   0.00000 | 151.593810 |  0.0000000 | 0 |  0.000000 | ⋯ | 0 |  0.0000000 | 155.596470 | 0 | 104.003006 |   0.000000 |  519.1849 |   0.00000 | 223.2976700 | 0 |\n",
       "| HNSCC17_P4_A02_S98_comb | 0 |  236.4461 |   0.000000 | 0 |   0.00000 |   0.00000 |   0.000000 |  0.0000000 | 0 |  0.000000 | ⋯ | 0 |  0.3700007 |   1.810008 | 0 |   0.000000 |   0.000000 |  834.0169 | 191.48492 |   0.0000000 | 0 |\n",
       "| HNSCC20_P13_D01_S229_comb | 0 |  339.5193 |   0.000000 | 0 |  88.75132 |   0.00000 | 125.197820 |  0.0000000 | 0 |  6.970040 | ⋯ | 0 |  0.7500249 |  63.589504 | 0 | 167.358920 |   0.000000 |  627.2555 |   0.00000 |   4.2599607 | 0 |\n",
       "| HNSCC20_P13_G02_S266_comb | 0 |  209.8275 |   0.000000 | 0 | 107.72918 |   0.00000 |   0.000000 |  0.0000000 | 0 |  0.000000 | ⋯ | 0 |  0.7600144 | 242.480480 | 0 |   0.000000 | 160.476380 |  516.6600 |   0.00000 |   1.5100173 | 0 |\n",
       "| HNSCC17_P4_B04_S112_comb | 0 | 1445.9329 |   0.000000 | 0 |   0.00000 |  86.65873 |   0.000000 |  0.7899636 | 0 |  0.000000 | ⋯ | 0 |  0.2900001 |  53.212067 | 0 | 186.696580 |   0.000000 | 1366.3466 | 189.59450 |  68.7292600 | 0 |\n",
       "| HNSCC17_P4_C09_S129_comb | 0 | 1028.6747 |   0.000000 | 0 |   0.00000 |  60.97938 |   0.000000 |  0.0000000 | 0 |  0.000000 | ⋯ | 0 |  0.2299990 | 134.971760 | 0 |   2.530031 |   1.719979 |  575.6229 | 404.24146 | 717.4115600 | 0 |\n",
       "| HNSCC20_P13_A12_S204_comb | 0 |  470.4119 |   0.000000 | 0 |  34.85908 |   0.00000 |  63.870586 |  0.0000000 | 0 |  0.000000 | ⋯ | 0 |  0.5500000 | 241.223590 | 0 | 147.414870 |   0.000000 |  276.5669 |  34.83110 |  62.6619450 | 0 |\n",
       "| HNSCC17_P4_F06_S162_comb | 0 | 2064.6152 |   0.000000 | 0 |   0.00000 |   0.00000 |   0.000000 |  1.6600178 | 0 |  0.000000 | ⋯ | 0 |  0.5999981 | 113.009680 | 0 |   1.330017 | 188.215790 |  587.3067 | 499.63766 |   2.8599942 | 0 |\n",
       "| HNSCC20_P3_B10_S22_comb | 0 | 1163.5211 |   0.000000 | 0 |  71.86234 |   0.00000 |   0.000000 |  0.0000000 | 0 |  0.000000 | ⋯ | 0 |  0.6599968 |  48.022000 | 0 |  56.479060 |   0.000000 |  460.1014 |  65.66888 | 158.0711200 | 0 |\n",
       "| HNSCC20_P13_B11_S215_comb | 0 |  614.6170 |   5.380048 | 0 |   0.00000 |   0.00000 |  69.878100 |  3.0200050 | 0 |  3.259993 | ⋯ | 0 | 15.1106610 |  94.338524 | 0 | 134.150100 |   0.000000 |  690.5422 |  23.28103 |  50.9911540 | 0 |\n",
       "| HNSCC20_P3_C08_S32_comb | 0 |  273.4849 |   0.000000 | 0 |   0.00000 |   0.00000 |   0.000000 | 30.4909650 | 0 |  0.000000 | ⋯ | 0 |  0.0000000 |   0.000000 | 0 |  98.709040 | 339.035030 |  207.5085 |  68.90955 | 316.0225800 | 0 |\n",
       "| HNSCC17_P4_H03_S183_comb | 0 | 1821.2692 |   0.000000 | 0 |   0.00000 |   0.00000 |   0.000000 |  0.5100024 | 0 |  0.000000 | ⋯ | 0 |  0.0000000 | 167.518810 | 0 |   0.000000 | 169.237430 |  569.3246 | 562.22076 | 261.9369000 | 0 |\n",
       "| HNSCC20_P3_F09_S69_comb | 0 | 1593.2993 |   0.000000 | 0 |   0.00000 |   0.00000 | 105.186520 |  0.0000000 | 0 |  0.000000 | ⋯ | 0 |  0.0000000 |  47.829273 | 0 |  58.229706 |   0.000000 |  532.5183 | 118.63399 |   0.7199636 | 0 |\n",
       "| HNSCC17_P4_G12_S180_comb | 0 |  400.5540 |   0.000000 | 0 |   0.00000 | 224.85526 |   0.000000 |  0.0000000 | 0 |  0.000000 | ⋯ | 0 |  0.4199980 | 171.626140 | 0 |   0.000000 |  35.690680 |  452.2495 |   0.00000 | 497.6984600 | 0 |\n",
       "| HNSCC20_P13_C05_S221_comb | 0 | 1712.1895 |   0.000000 | 0 |   0.00000 |   0.00000 | 280.567200 |  0.0000000 | 0 |  8.780038 | ⋯ | 0 |  1.8500241 |   0.000000 | 0 |   0.000000 |   0.000000 |  146.6964 |   0.00000 |   9.0699360 | 0 |\n",
       "| HNSCC17_P4_C12_S132_comb | 0 | 1138.7333 |  87.560690 | 0 |   0.00000 |   0.00000 |   0.000000 |  0.0000000 | 0 |  0.000000 | ⋯ | 0 | 39.6089360 |  98.829666 | 0 |  42.039246 |   0.000000 |  734.7581 | 213.79408 | 269.4271000 | 0 |\n",
       "| HNSCC20_P3_H08_S92_comb | 0 | 1157.7600 |   0.000000 | 0 | 396.78653 |   0.00000 | 209.614290 |  2.5999675 | 0 |  0.000000 | ⋯ | 0 |  0.8699854 |   0.000000 | 0 | 157.861560 |  17.220621 |  570.2891 |   0.00000 |   0.8399643 | 0 |\n",
       "| HNSCC20_P3_G06_S78_comb | 0 |  785.9467 | 110.461480 | 0 |   0.00000 |   0.00000 |   0.000000 | 74.4618600 | 0 |  3.249978 | ⋯ | 0 |  0.0000000 |  92.681190 | 0 | 322.296700 |   0.000000 |  547.7706 |  89.21099 | 388.0009500 | 0 |\n",
       "\n"
      ],
      "text/plain": [
       "                          C9orf152 RPS11     ELMO2       CREB3L1  PNMA1     \n",
       "HN28_P15_D06_S330_comb    0.000000  631.6435   0.0000000 0.000000 344.422900\n",
       "HN28_P6_G05_S173_comb     0.000000 1566.5204   0.0000000 0.000000 393.053650\n",
       "HN26_P14_D11_S239_comb    3.450036 1553.3533   0.0000000 0.000000  61.290012\n",
       "HN26_P14_H05_S281_comb    0.000000    0.0000 369.6241800 0.000000 528.434900\n",
       "HN26_P25_H09_S189_comb    0.000000 1768.1090   4.1899548 0.000000   1.460023\n",
       "HN26_P14_H06_S282_comb    0.000000 1230.5189   0.0000000 0.000000  29.858847\n",
       "HN25_P25_C04_S316_comb    0.000000  618.7001   0.0000000 0.000000   0.000000\n",
       "HN26_P25_A11_S107_comb    0.000000  873.4031  96.6934740 0.000000  34.509090\n",
       "HN26_P25_C09_S129_comb    0.000000  935.3653   0.0000000 0.000000 109.712340\n",
       "HNSCC26_P24_H05_S377_comb 0.000000 2460.3984  28.9412700 0.000000   0.000000\n",
       "HN25_P5_E10_S58_comb      0.000000  664.2445   0.0000000 0.000000 209.857990\n",
       "HN25_P24_B02_S110_comb    0.000000 1829.2834  58.6376400 0.000000  23.410463\n",
       "HN25_P25_C01_S313_comb    0.000000 1846.9614   0.0000000 0.000000 437.495120\n",
       "HN28_P15_G06_S366_comb    0.000000  590.3367   0.0000000 0.000000   0.000000\n",
       "HN26_P6_B06_S18_comb      0.000000    0.0000   0.0000000 0.000000   0.000000\n",
       "HN25_P5_C05_S29_comb      0.000000  375.4308  94.4108660 0.000000   0.000000\n",
       "HN28_P6_D09_S141_comb     0.000000 2414.9312   0.0000000 0.000000   0.000000\n",
       "HN26_P5_H01_S85_comb      0.000000 1616.3568   0.5800027 6.390047   0.000000\n",
       "HN26_P13_D07_S139_comb    0.000000  853.7249   0.0000000 0.000000   0.000000\n",
       "HN26_P5_E06_S54_comb      0.000000  956.7695   1.1000025 0.000000   0.000000\n",
       "HN26_P26_H05_S377_comb    0.000000 1412.8108   0.0000000 0.000000  30.000000\n",
       "HNSCC26_P24_F12_S360_comb 0.000000 1732.4820   0.0000000 0.000000   0.000000\n",
       "HNSCC26_P24_F03_S351_comb 0.000000 1171.4379 123.3827300 0.000000   0.000000\n",
       "HN26_P6_D08_S44_comb      0.000000  306.2295   0.0000000 0.000000   0.000000\n",
       "HN25_P5_E12_S60_comb      0.000000  346.3937 112.7796860 0.000000   3.870021\n",
       "HNSCC26_P24_C01_S313_comb 0.000000 1572.8711  33.7687150 0.000000  70.411400\n",
       "HN25_P5_F01_S61_comb      0.000000  820.4952   0.0000000 0.000000 530.266700\n",
       "HN26_P5_D12_S48_comb      0.000000 1070.5334   0.0000000 0.000000   0.000000\n",
       "HN25_P25_C11_S323_comb    0.000000 1415.6737 225.6379500 0.000000   0.000000\n",
       "HN25_P25_B12_S312_comb    0.000000 1473.4371   0.0000000 0.000000   0.000000\n",
       "⋮                         ⋮        ⋮         ⋮           ⋮        ⋮         \n",
       "HNSCC17_P4_A08_S104_comb  0         469.1814   0.000000  0          0.00000 \n",
       "HNSCC17_P4_E10_S154_comb  0        1168.4935   0.000000  0          0.00000 \n",
       "HNSCC17_P4_E02_S146_comb  0         825.4607   0.000000  0          0.00000 \n",
       "HNSCC20_P13_F10_S262_comb 0         957.1716 164.868680  0          0.00000 \n",
       "HNSCC17_P4_D04_S136_comb  0         654.2250   4.450005  0          0.00000 \n",
       "HNSCC20_P13_C06_S222_comb 0         947.6324   0.000000  0          0.00000 \n",
       "HNSCC20_P13_C12_S228_comb 0        1294.9042  74.661150  0          0.00000 \n",
       "HNSCC17_P4_H04_S184_comb  0         671.7165   0.000000  0          0.00000 \n",
       "HNSCC17_P4_C06_S126_comb  0         846.6892  10.820432  0          0.00000 \n",
       "HNSCC20_P3_D01_S37_comb   0         939.7000  67.280266  0         66.31148 \n",
       "HNSCC20_P3_D09_S45_comb   0         930.5939  86.611840  0         43.43185 \n",
       "HNSCC17_P4_E06_S150_comb  0         989.4760  25.369358  0          0.00000 \n",
       "HNSCC20_P13_H10_S286_comb 0         792.4280   0.000000  0         77.79264 \n",
       "HNSCC17_P4_A02_S98_comb   0         236.4461   0.000000  0          0.00000 \n",
       "HNSCC20_P13_D01_S229_comb 0         339.5193   0.000000  0         88.75132 \n",
       "HNSCC20_P13_G02_S266_comb 0         209.8275   0.000000  0        107.72918 \n",
       "HNSCC17_P4_B04_S112_comb  0        1445.9329   0.000000  0          0.00000 \n",
       "HNSCC17_P4_C09_S129_comb  0        1028.6747   0.000000  0          0.00000 \n",
       "HNSCC20_P13_A12_S204_comb 0         470.4119   0.000000  0         34.85908 \n",
       "HNSCC17_P4_F06_S162_comb  0        2064.6152   0.000000  0          0.00000 \n",
       "HNSCC20_P3_B10_S22_comb   0        1163.5211   0.000000  0         71.86234 \n",
       "HNSCC20_P13_B11_S215_comb 0         614.6170   5.380048  0          0.00000 \n",
       "HNSCC20_P3_C08_S32_comb   0         273.4849   0.000000  0          0.00000 \n",
       "HNSCC17_P4_H03_S183_comb  0        1821.2692   0.000000  0          0.00000 \n",
       "HNSCC20_P3_F09_S69_comb   0        1593.2993   0.000000  0          0.00000 \n",
       "HNSCC17_P4_G12_S180_comb  0         400.5540   0.000000  0          0.00000 \n",
       "HNSCC20_P13_C05_S221_comb 0        1712.1895   0.000000  0          0.00000 \n",
       "HNSCC17_P4_C12_S132_comb  0        1138.7333  87.560690  0          0.00000 \n",
       "HNSCC20_P3_H08_S92_comb   0        1157.7600   0.000000  0        396.78653 \n",
       "HNSCC20_P3_G06_S78_comb   0         785.9467 110.461480  0          0.00000 \n",
       "                          MMP2        TMEM216    TRAF3IP2-AS1 LRRC37A5P\n",
       "HN28_P15_D06_S330_comb       0.000000   0.000000  2.3099935   0        \n",
       "HN28_P6_G05_S173_comb        0.000000   0.000000  5.0599813   0        \n",
       "HN26_P14_D11_S239_comb       0.000000 111.593990  0.9499934   0        \n",
       "HN26_P14_H05_S281_comb       0.000000 309.512400 87.4187850   0        \n",
       "HN26_P25_H09_S189_comb       2.840043   0.000000  1.1799985   0        \n",
       "HN26_P14_H06_S282_comb       0.000000   0.000000  0.7399703   0        \n",
       "HN25_P25_C04_S316_comb       0.000000   0.000000  9.9299760   0        \n",
       "HN26_P25_A11_S107_comb       0.000000   8.260041 90.2131600   0        \n",
       "HN26_P25_C09_S129_comb       0.000000   0.000000  0.6100025   0        \n",
       "HNSCC26_P24_H05_S377_comb    0.000000 188.298250  5.7699710   0        \n",
       "HN25_P5_E10_S58_comb         0.000000 214.586610  1.9299666   0        \n",
       "HN25_P24_B02_S110_comb       0.000000  22.729690  0.0000000   0        \n",
       "HN25_P25_C01_S313_comb       0.000000   0.000000  1.8700005   0        \n",
       "HN28_P15_G06_S366_comb       0.000000   0.000000 61.2504920   0        \n",
       "HN26_P6_B06_S18_comb         0.000000   0.000000  1.6899600   0        \n",
       "HN25_P5_C05_S29_comb      1109.491700   0.000000  1.2300161   0        \n",
       "HN28_P6_D09_S141_comb        0.000000   0.000000  7.5400150   0        \n",
       "HN26_P5_H01_S85_comb         0.000000   0.000000  0.0000000   0        \n",
       "HN26_P13_D07_S139_comb       0.000000   0.000000 10.9101010   0        \n",
       "HN26_P5_E06_S54_comb         0.000000   0.000000  3.5100217   0        \n",
       "HN26_P26_H05_S377_comb       0.000000   0.000000  0.6599968   0        \n",
       "HNSCC26_P24_F12_S360_comb    0.000000 450.841920  2.0899644   0        \n",
       "HNSCC26_P24_F03_S351_comb    0.000000   0.000000  0.0000000   0        \n",
       "HN26_P6_D08_S44_comb         0.000000   0.000000  4.1399794   0        \n",
       "HN25_P5_E12_S60_comb         0.000000 153.826860  0.0000000   0        \n",
       "HNSCC26_P24_C01_S313_comb    0.000000   0.000000 20.6099360   0        \n",
       "HN25_P5_F01_S61_comb         0.000000   0.000000  2.2799952   0        \n",
       "HN26_P5_D12_S48_comb         0.000000   0.000000  0.0000000   0        \n",
       "HN25_P25_C11_S323_comb     211.525360   0.000000  0.0000000   0        \n",
       "HN25_P25_B12_S312_comb       4.119999   0.000000  0.4800021   0        \n",
       "⋮                         ⋮           ⋮          ⋮            ⋮        \n",
       "HNSCC17_P4_A08_S104_comb    0.00000     0.000000  0.0000000   0        \n",
       "HNSCC17_P4_E10_S154_comb    0.00000     0.000000  0.7299994   0        \n",
       "HNSCC17_P4_E02_S146_comb    0.00000     0.000000  0.4800021   0        \n",
       "HNSCC20_P13_F10_S262_comb   0.00000   186.043240  1.9899862   0        \n",
       "HNSCC17_P4_D04_S136_comb  107.05381     0.000000  1.6699631   0        \n",
       "HNSCC20_P13_C06_S222_comb   0.00000   107.859820  1.4799789   0        \n",
       "HNSCC20_P13_C12_S228_comb   0.00000     0.000000  0.0000000   0        \n",
       "HNSCC17_P4_H04_S184_comb   16.86076     0.000000  0.0000000   0        \n",
       "HNSCC17_P4_C06_S126_comb    0.00000     3.520046  0.0000000   0        \n",
       "HNSCC20_P3_D01_S37_comb     0.00000    81.838560  0.0000000   0        \n",
       "HNSCC20_P3_D09_S45_comb     0.00000   165.902010  0.0000000   0        \n",
       "HNSCC17_P4_E06_S150_comb   21.50979   139.254240  1.9600216   0        \n",
       "HNSCC20_P13_H10_S286_comb   0.00000   151.593810  0.0000000   0        \n",
       "HNSCC17_P4_A02_S98_comb     0.00000     0.000000  0.0000000   0        \n",
       "HNSCC20_P13_D01_S229_comb   0.00000   125.197820  0.0000000   0        \n",
       "HNSCC20_P13_G02_S266_comb   0.00000     0.000000  0.0000000   0        \n",
       "HNSCC17_P4_B04_S112_comb   86.65873     0.000000  0.7899636   0        \n",
       "HNSCC17_P4_C09_S129_comb   60.97938     0.000000  0.0000000   0        \n",
       "HNSCC20_P13_A12_S204_comb   0.00000    63.870586  0.0000000   0        \n",
       "HNSCC17_P4_F06_S162_comb    0.00000     0.000000  1.6600178   0        \n",
       "HNSCC20_P3_B10_S22_comb     0.00000     0.000000  0.0000000   0        \n",
       "HNSCC20_P13_B11_S215_comb   0.00000    69.878100  3.0200050   0        \n",
       "HNSCC20_P3_C08_S32_comb     0.00000     0.000000 30.4909650   0        \n",
       "HNSCC17_P4_H03_S183_comb    0.00000     0.000000  0.5100024   0        \n",
       "HNSCC20_P3_F09_S69_comb     0.00000   105.186520  0.0000000   0        \n",
       "HNSCC17_P4_G12_S180_comb  224.85526     0.000000  0.0000000   0        \n",
       "HNSCC20_P13_C05_S221_comb   0.00000   280.567200  0.0000000   0        \n",
       "HNSCC17_P4_C12_S132_comb    0.00000     0.000000  0.0000000   0        \n",
       "HNSCC20_P3_H08_S92_comb     0.00000   209.614290  2.5999675   0        \n",
       "HNSCC20_P3_G06_S78_comb     0.00000     0.000000 74.4618600   0        \n",
       "                          LOC653712 ⋯ MIR4691 GPLD1       RAB8A      RXFP2\n",
       "HN28_P15_D06_S330_comb    0.000000  ⋯ 0        0.90999170   1.280023 0    \n",
       "HN28_P6_G05_S173_comb     0.000000  ⋯ 0        0.00000000   0.000000 0    \n",
       "HN26_P14_D11_S239_comb    0.000000  ⋯ 0        0.00000000   9.069936 0    \n",
       "HN26_P14_H05_S281_comb    0.000000  ⋯ 0        0.32999817 456.466000 0    \n",
       "HN26_P25_H09_S189_comb    0.000000  ⋯ 0        0.49000233   2.409973 0    \n",
       "HN26_P14_H06_S282_comb    0.000000  ⋯ 0        0.37000075 141.337750 0    \n",
       "HN25_P25_C04_S316_comb    0.000000  ⋯ 0        0.00000000   0.000000 0    \n",
       "HN26_P25_A11_S107_comb    0.000000  ⋯ 0        0.00000000 184.986190 0    \n",
       "HN26_P25_C09_S129_comb    0.000000  ⋯ 0        0.00000000   0.000000 0    \n",
       "HNSCC26_P24_H05_S377_comb 0.000000  ⋯ 0        0.00000000   0.000000 0    \n",
       "HN25_P5_E10_S58_comb      0.000000  ⋯ 0        0.00000000  95.538680 0    \n",
       "HN25_P24_B02_S110_comb    0.000000  ⋯ 0        0.00000000 116.819084 0    \n",
       "HN25_P25_C01_S313_comb    0.000000  ⋯ 0        0.00000000   0.000000 0    \n",
       "HN28_P15_G06_S366_comb    0.000000  ⋯ 0        0.00000000   0.000000 0    \n",
       "HN26_P6_B06_S18_comb      0.000000  ⋯ 0        0.00000000   0.000000 0    \n",
       "HN25_P5_C05_S29_comb      0.000000  ⋯ 0        0.00000000  43.911760 0    \n",
       "HN28_P6_D09_S141_comb     0.000000  ⋯ 0        0.00000000   0.000000 0    \n",
       "HN26_P5_H01_S85_comb      0.000000  ⋯ 0        0.41999800   0.000000 0    \n",
       "HN26_P13_D07_S139_comb    0.000000  ⋯ 0        0.00000000   0.000000 0    \n",
       "HN26_P5_E06_S54_comb      0.000000  ⋯ 0        1.63999140  48.628414 0    \n",
       "HN26_P26_H05_S377_comb    0.000000  ⋯ 0        0.49000233 103.380450 0    \n",
       "HNSCC26_P24_F12_S360_comb 0.000000  ⋯ 0       17.49939700   3.340012 0    \n",
       "HNSCC26_P24_F03_S351_comb 0.000000  ⋯ 0        1.23001610  81.577934 0    \n",
       "HN26_P6_D08_S44_comb      2.360011  ⋯ 0        0.08999878 117.612700 0    \n",
       "HN25_P5_E12_S60_comb      0.000000  ⋯ 0        0.83996430 109.978165 0    \n",
       "HNSCC26_P24_C01_S313_comb 0.000000  ⋯ 0       54.01012000   0.000000 0    \n",
       "HN25_P5_F01_S61_comb      0.000000  ⋯ 0        1.12997230   0.000000 0    \n",
       "HN26_P5_D12_S48_comb      0.000000  ⋯ 0        0.00000000   0.000000 0    \n",
       "HN25_P25_C11_S323_comb    0.000000  ⋯ 0        0.90001410   0.000000 0    \n",
       "HN25_P25_B12_S312_comb    0.000000  ⋯ 0        0.35000166  75.771600 0    \n",
       "⋮                         ⋮         ⋱ ⋮       ⋮           ⋮          ⋮    \n",
       "HNSCC17_P4_A08_S104_comb   0.000000 ⋯ 0        0.0000000   63.737576 0    \n",
       "HNSCC17_P4_E10_S154_comb   0.000000 ⋯ 0        0.7800211  256.820950 0    \n",
       "HNSCC17_P4_E02_S146_comb   0.000000 ⋯ 0        0.0000000  193.266420 0    \n",
       "HNSCC20_P13_F10_S262_comb  0.000000 ⋯ 0       16.6493430   44.800915 0    \n",
       "HNSCC17_P4_D04_S136_comb   0.000000 ⋯ 0        0.0000000    0.000000 0    \n",
       "HNSCC20_P13_C06_S222_comb 16.140740 ⋯ 0        0.0000000   79.370580 0    \n",
       "HNSCC20_P13_C12_S228_comb  0.000000 ⋯ 0        0.0000000  184.405880 0    \n",
       "HNSCC17_P4_H04_S184_comb   0.000000 ⋯ 0        0.0000000   30.401253 0    \n",
       "HNSCC17_P4_C06_S126_comb   0.000000 ⋯ 0        0.5699973   82.541466 0    \n",
       "HNSCC20_P3_D01_S37_comb   37.640877 ⋯ 0        0.0000000   56.848724 0    \n",
       "HNSCC20_P3_D09_S45_comb    0.000000 ⋯ 0        2.4400303   29.400120 0    \n",
       "HNSCC17_P4_E06_S150_comb   0.000000 ⋯ 0        0.0000000  127.446660 0    \n",
       "HNSCC20_P13_H10_S286_comb  0.000000 ⋯ 0        0.0000000  155.596470 0    \n",
       "HNSCC17_P4_A02_S98_comb    0.000000 ⋯ 0        0.3700007    1.810008 0    \n",
       "HNSCC20_P13_D01_S229_comb  6.970040 ⋯ 0        0.7500249   63.589504 0    \n",
       "HNSCC20_P13_G02_S266_comb  0.000000 ⋯ 0        0.7600144  242.480480 0    \n",
       "HNSCC17_P4_B04_S112_comb   0.000000 ⋯ 0        0.2900001   53.212067 0    \n",
       "HNSCC17_P4_C09_S129_comb   0.000000 ⋯ 0        0.2299990  134.971760 0    \n",
       "HNSCC20_P13_A12_S204_comb  0.000000 ⋯ 0        0.5500000  241.223590 0    \n",
       "HNSCC17_P4_F06_S162_comb   0.000000 ⋯ 0        0.5999981  113.009680 0    \n",
       "HNSCC20_P3_B10_S22_comb    0.000000 ⋯ 0        0.6599968   48.022000 0    \n",
       "HNSCC20_P13_B11_S215_comb  3.259993 ⋯ 0       15.1106610   94.338524 0    \n",
       "HNSCC20_P3_C08_S32_comb    0.000000 ⋯ 0        0.0000000    0.000000 0    \n",
       "HNSCC17_P4_H03_S183_comb   0.000000 ⋯ 0        0.0000000  167.518810 0    \n",
       "HNSCC20_P3_F09_S69_comb    0.000000 ⋯ 0        0.0000000   47.829273 0    \n",
       "HNSCC17_P4_G12_S180_comb   0.000000 ⋯ 0        0.4199980  171.626140 0    \n",
       "HNSCC20_P13_C05_S221_comb  8.780038 ⋯ 0        1.8500241    0.000000 0    \n",
       "HNSCC17_P4_C12_S132_comb   0.000000 ⋯ 0       39.6089360   98.829666 0    \n",
       "HNSCC20_P3_H08_S92_comb    0.000000 ⋯ 0        0.8699854    0.000000 0    \n",
       "HNSCC20_P3_G06_S78_comb    3.249978 ⋯ 0        0.0000000   92.681190 0    \n",
       "                          PCIF1       PIK3IP1    SNRPD2    SLC39A6   \n",
       "HN28_P15_D06_S330_comb    156.2981300   0.000000   0.00000   0.000000\n",
       "HN28_P6_G05_S173_comb     758.5674400   0.000000 329.32600   0.000000\n",
       "HN26_P14_D11_S239_comb    160.2638200  71.308150 557.75635   0.000000\n",
       "HN26_P14_H05_S281_comb      0.0000000 764.020570   0.00000   0.000000\n",
       "HN26_P25_H09_S189_comb    251.8193800 131.830900 204.93076   0.000000\n",
       "HN26_P14_H06_S282_comb      9.1300410 118.180060 634.45154  35.299652\n",
       "HN25_P25_C04_S316_comb      0.0000000   0.000000   0.00000   0.000000\n",
       "HN26_P25_A11_S107_comb     61.1616500   0.000000   0.00000   0.000000\n",
       "HN26_P25_C09_S129_comb      0.0000000   0.000000 338.11690   0.000000\n",
       "HNSCC26_P24_H05_S377_comb   0.0000000   0.000000 423.54205   0.000000\n",
       "HN25_P5_E10_S58_comb      157.4548200   8.780038   0.00000 273.878170\n",
       "HN25_P24_B02_S110_comb     39.8295000   0.000000 136.93437  64.060280\n",
       "HN25_P25_C01_S313_comb     76.0395500   0.000000 742.48975   0.000000\n",
       "HN28_P15_G06_S366_comb      0.0000000   0.000000 307.01956   0.000000\n",
       "HN26_P6_B06_S18_comb        0.0000000   0.000000   0.00000   0.000000\n",
       "HN25_P5_C05_S29_comb        0.0000000   0.000000 155.76874   0.000000\n",
       "HN28_P6_D09_S141_comb       0.0000000   0.000000   0.00000   0.000000\n",
       "HN26_P5_H01_S85_comb        0.7899636   0.000000 549.12540   0.000000\n",
       "HN26_P13_D07_S139_comb      0.0000000   0.000000   0.00000   0.000000\n",
       "HN26_P5_E06_S54_comb        0.0000000   0.000000 444.43436  62.737534\n",
       "HN26_P26_H05_S377_comb    153.5545500   0.000000 432.62100   6.879942\n",
       "HNSCC26_P24_F12_S360_comb   0.0000000   0.000000 583.79785 140.793260\n",
       "HNSCC26_P24_F03_S351_comb 357.9403400   0.000000 359.01306  60.201410\n",
       "HN26_P6_D08_S44_comb        0.0000000 573.677700  73.17789 259.180100\n",
       "HN25_P5_E12_S60_comb        0.0000000   0.000000 220.74060 172.927490\n",
       "HNSCC26_P24_C01_S313_comb  95.6631200  86.277590 674.13070  27.310974\n",
       "HN25_P5_F01_S61_comb        0.0000000   0.000000   0.00000   0.000000\n",
       "HN26_P5_D12_S48_comb       12.3503895   0.000000   0.00000   0.000000\n",
       "HN25_P25_C11_S323_comb    172.3957200   0.000000 199.14041   0.000000\n",
       "HN25_P25_B12_S312_comb     14.1998820   0.000000 418.52280  28.989887\n",
       "⋮                         ⋮           ⋮          ⋮         ⋮         \n",
       "HNSCC17_P4_A08_S104_comb   54.620860   53.899296  920.3489 311.53415 \n",
       "HNSCC17_P4_E10_S154_comb    0.000000   89.721180  494.7160 131.82108 \n",
       "HNSCC17_P4_E02_S146_comb    0.000000    0.000000  453.7901 109.19898 \n",
       "HNSCC20_P13_F10_S262_comb  97.868370  476.949400  552.9364   0.00000 \n",
       "HNSCC17_P4_D04_S136_comb   12.019779    0.000000  556.6555 394.08868 \n",
       "HNSCC20_P13_C06_S222_comb   8.320006   96.553055  347.4576  58.30068 \n",
       "HNSCC20_P13_C12_S228_comb  64.327705   54.580563 1089.3447   0.00000 \n",
       "HNSCC17_P4_H04_S184_comb    0.000000    0.000000  967.8898  43.62107 \n",
       "HNSCC17_P4_C06_S126_comb   54.661186   40.210880  351.1685  48.84011 \n",
       "HNSCC20_P3_D01_S37_comb    71.161750    0.000000  407.3541  45.82843 \n",
       "HNSCC20_P3_D09_S45_comb    75.391945    0.000000  584.3332   0.00000 \n",
       "HNSCC17_P4_E06_S150_comb   65.878970    0.000000  581.6204 185.17549 \n",
       "HNSCC20_P13_H10_S286_comb 104.003006    0.000000  519.1849   0.00000 \n",
       "HNSCC17_P4_A02_S98_comb     0.000000    0.000000  834.0169 191.48492 \n",
       "HNSCC20_P13_D01_S229_comb 167.358920    0.000000  627.2555   0.00000 \n",
       "HNSCC20_P13_G02_S266_comb   0.000000  160.476380  516.6600   0.00000 \n",
       "HNSCC17_P4_B04_S112_comb  186.696580    0.000000 1366.3466 189.59450 \n",
       "HNSCC17_P4_C09_S129_comb    2.530031    1.719979  575.6229 404.24146 \n",
       "HNSCC20_P13_A12_S204_comb 147.414870    0.000000  276.5669  34.83110 \n",
       "HNSCC17_P4_F06_S162_comb    1.330017  188.215790  587.3067 499.63766 \n",
       "HNSCC20_P3_B10_S22_comb    56.479060    0.000000  460.1014  65.66888 \n",
       "HNSCC20_P13_B11_S215_comb 134.150100    0.000000  690.5422  23.28103 \n",
       "HNSCC20_P3_C08_S32_comb    98.709040  339.035030  207.5085  68.90955 \n",
       "HNSCC17_P4_H03_S183_comb    0.000000  169.237430  569.3246 562.22076 \n",
       "HNSCC20_P3_F09_S69_comb    58.229706    0.000000  532.5183 118.63399 \n",
       "HNSCC17_P4_G12_S180_comb    0.000000   35.690680  452.2495   0.00000 \n",
       "HNSCC20_P13_C05_S221_comb   0.000000    0.000000  146.6964   0.00000 \n",
       "HNSCC17_P4_C12_S132_comb   42.039246    0.000000  734.7581 213.79408 \n",
       "HNSCC20_P3_H08_S92_comb   157.861560   17.220621  570.2891   0.00000 \n",
       "HNSCC20_P3_G06_S78_comb   322.296700    0.000000  547.7706  89.21099 \n",
       "                          CTSC        AQP7    \n",
       "HN28_P15_D06_S330_comb      0.4400021  0.00000\n",
       "HN28_P6_G05_S173_comb       2.1599727  0.00000\n",
       "HN26_P14_D11_S239_comb    121.7380300  0.00000\n",
       "HN26_P14_H05_S281_comb      1.2399842  0.00000\n",
       "HN26_P25_H09_S189_comb     96.6269300  0.00000\n",
       "HN26_P14_H06_S282_comb    323.1500000  0.00000\n",
       "HN25_P25_C04_S316_comb     36.9394200  0.00000\n",
       "HN26_P25_A11_S107_comb      1.7899696  0.00000\n",
       "HN26_P25_C09_S129_comb    237.1645700  0.00000\n",
       "HNSCC26_P24_H05_S377_comb   3.0300264  0.00000\n",
       "HN25_P5_E10_S58_comb       26.9199350  0.00000\n",
       "HN25_P24_B02_S110_comb    158.0827800  0.00000\n",
       "HN25_P25_C01_S313_comb      1.8900106  0.00000\n",
       "HN28_P15_G06_S366_comb      0.6200017  0.00000\n",
       "HN26_P6_B06_S18_comb        0.5600012  0.00000\n",
       "HN25_P5_C05_S29_comb      672.6149000  0.00000\n",
       "HN28_P6_D09_S141_comb       5.2099986  0.00000\n",
       "HN26_P5_H01_S85_comb       65.8789700  0.00000\n",
       "HN26_P13_D07_S139_comb      1.8500241  0.00000\n",
       "HN26_P5_E06_S54_comb        1.6199994 12.16065\n",
       "HN26_P26_H05_S377_comb     68.2776260  0.00000\n",
       "HNSCC26_P24_F12_S360_comb  10.7901480  0.00000\n",
       "HNSCC26_P24_F03_S351_comb 172.1304200  0.00000\n",
       "HN26_P6_D08_S44_comb        2.5600307  0.00000\n",
       "HN25_P5_E12_S60_comb        0.8100261  0.00000\n",
       "HNSCC26_P24_C01_S313_comb 418.6416000  0.00000\n",
       "HN25_P5_F01_S61_comb        1.5700091  0.00000\n",
       "HN26_P5_D12_S48_comb       11.4905140  0.00000\n",
       "HN25_P25_C11_S323_comb      3.3800175  0.00000\n",
       "HN25_P25_B12_S312_comb     11.7407250  0.00000\n",
       "⋮                         ⋮           ⋮       \n",
       "HNSCC17_P4_A08_S104_comb  107.6965400 0       \n",
       "HNSCC17_P4_E10_S154_comb    2.2299626 0       \n",
       "HNSCC17_P4_E02_S146_comb  306.9316700 0       \n",
       "HNSCC20_P13_F10_S262_comb 187.6943800 0       \n",
       "HNSCC17_P4_D04_S136_comb  908.3677000 0       \n",
       "HNSCC20_P13_C06_S222_comb 171.0228600 0       \n",
       "HNSCC20_P13_C12_S228_comb  16.6401100 0       \n",
       "HNSCC17_P4_H04_S184_comb  104.4463900 0       \n",
       "HNSCC17_P4_C06_S126_comb  323.1962000 0       \n",
       "HNSCC20_P3_D01_S37_comb     0.0000000 0       \n",
       "HNSCC20_P3_D09_S45_comb   339.3255000 0       \n",
       "HNSCC17_P4_E06_S150_comb  275.8725000 0       \n",
       "HNSCC20_P13_H10_S286_comb 223.2976700 0       \n",
       "HNSCC17_P4_A02_S98_comb     0.0000000 0       \n",
       "HNSCC20_P13_D01_S229_comb   4.2599607 0       \n",
       "HNSCC20_P13_G02_S266_comb   1.5100173 0       \n",
       "HNSCC17_P4_B04_S112_comb   68.7292600 0       \n",
       "HNSCC17_P4_C09_S129_comb  717.4115600 0       \n",
       "HNSCC20_P13_A12_S204_comb  62.6619450 0       \n",
       "HNSCC17_P4_F06_S162_comb    2.8599942 0       \n",
       "HNSCC20_P3_B10_S22_comb   158.0711200 0       \n",
       "HNSCC20_P13_B11_S215_comb  50.9911540 0       \n",
       "HNSCC20_P3_C08_S32_comb   316.0225800 0       \n",
       "HNSCC17_P4_H03_S183_comb  261.9369000 0       \n",
       "HNSCC20_P3_F09_S69_comb     0.7199636 0       \n",
       "HNSCC17_P4_G12_S180_comb  497.6984600 0       \n",
       "HNSCC20_P13_C05_S221_comb   9.0699360 0       \n",
       "HNSCC17_P4_C12_S132_comb  269.4271000 0       \n",
       "HNSCC20_P3_H08_S92_comb     0.8399643 0       \n",
       "HNSCC20_P3_G06_S78_comb   388.0009500 0       "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "df_Puram"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 4,
   "id": "e557f109",
   "metadata": {},
   "outputs": [],
   "source": [
    "df_TCGA <- read.table(\"/home/cke/TCGA-HNSC.htseq_counts_exp2_symbol_samplexgene.tsv\",sep='\\t',header=TRUE,row.names = 1,check.names = FALSE)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 33,
   "id": "5b385b94",
   "metadata": {},
   "outputs": [],
   "source": [
    "df_TCGA<-data.matrix(df_TCGA)\n",
    "# colnames(df_TCGA_t)<-df_TCGA_t[1,]\n",
    "# df_TCGA_t <- df_TCGA_t[-1,]"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 34,
   "id": "cea09399",
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<table class=\"dataframe\">\n",
       "<caption>A matrix: 546 × 38929 of type dbl</caption>\n",
       "<thead>\n",
       "\t<tr><th></th><th scope=col>TSPAN6</th><th scope=col>TNMD</th><th scope=col>DPM1</th><th scope=col>SCYL3</th><th scope=col>C1orf112</th><th scope=col>FGR</th><th scope=col>CFH</th><th scope=col>FUCA2</th><th scope=col>GCLC</th><th scope=col>NFYA</th><th scope=col>⋯</th><th scope=col>LINC00550</th><th scope=col>LINC01394</th><th scope=col>LINC00602</th><th scope=col>MIR1291</th><th scope=col>LINC00891</th><th scope=col>PAUPAR</th><th scope=col>GIMAP1-GIMAP5</th><th scope=col>LINC02246</th><th scope=col>HERC2P7</th><th scope=col>LINC01144</th></tr>\n",
       "</thead>\n",
       "<tbody>\n",
       "\t<tr><th scope=row>TCGA-BB-4224-01A</th><td> 2237</td><td> 2</td><td>1606</td><td>1063</td><td>1208</td><td> 256</td><td>  177</td><td>2371</td><td> 2741</td><td>2515</td><td>⋯</td><td>6</td><td>7</td><td>0</td><td> 2</td><td>0</td><td>6</td><td>0</td><td>16</td><td>0</td><td>144</td></tr>\n",
       "\t<tr><th scope=row>TCGA-H7-7774-01A</th><td> 2740</td><td> 0</td><td>1691</td><td> 803</td><td> 317</td><td> 330</td><td> 5472</td><td>2316</td><td> 8370</td><td> 816</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td> 0</td><td>2</td><td>0</td><td>0</td><td> 6</td><td>0</td><td> 23</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6943-01A</th><td> 2686</td><td> 0</td><td>1649</td><td> 917</td><td> 402</td><td>1535</td><td>15358</td><td>3490</td><td> 4671</td><td>2080</td><td>⋯</td><td>0</td><td>4</td><td>0</td><td> 2</td><td>4</td><td>1</td><td>0</td><td>38</td><td>0</td><td> 18</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-5374-01A</th><td> 2086</td><td> 1</td><td>2333</td><td>1288</td><td>1105</td><td> 639</td><td> 5565</td><td>2065</td><td> 2902</td><td>1777</td><td>⋯</td><td>0</td><td>0</td><td>1</td><td> 0</td><td>3</td><td>0</td><td>0</td><td> 4</td><td>0</td><td> 31</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CQ-6227-01A</th><td>10167</td><td> 9</td><td>3021</td><td> 537</td><td> 459</td><td> 362</td><td> 6963</td><td>4883</td><td> 3140</td><td>2448</td><td>⋯</td><td>1</td><td>3</td><td>0</td><td> 0</td><td>2</td><td>0</td><td>0</td><td>15</td><td>0</td><td> 24</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6959-01A</th><td> 1154</td><td> 6</td><td>2766</td><td> 527</td><td> 747</td><td> 906</td><td>12856</td><td>6120</td><td> 7448</td><td>3527</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td> 1</td><td>3</td><td>1</td><td>0</td><td>19</td><td>1</td><td> 15</td></tr>\n",
       "\t<tr><th scope=row>TCGA-F7-A61V-01A</th><td> 1978</td><td> 1</td><td>1762</td><td> 482</td><td> 331</td><td> 147</td><td>  793</td><td>2364</td><td> 2827</td><td>1159</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td> 1</td><td>1</td><td>0</td><td>0</td><td>15</td><td>0</td><td> 20</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7413-01A</th><td> 1930</td><td> 1</td><td>1668</td><td> 671</td><td> 476</td><td> 477</td><td> 3669</td><td>3366</td><td> 2324</td><td>1459</td><td>⋯</td><td>0</td><td>3</td><td>0</td><td> 0</td><td>1</td><td>0</td><td>0</td><td>19</td><td>1</td><td> 23</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7247-01A</th><td> 1066</td><td> 1</td><td>1760</td><td> 600</td><td> 874</td><td> 204</td><td> 2791</td><td>1837</td><td> 9779</td><td>1916</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td> 0</td><td>1</td><td>0</td><td>0</td><td>17</td><td>1</td><td> 43</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CR-5249-01A</th><td> 2538</td><td> 0</td><td>1268</td><td>1066</td><td> 950</td><td> 924</td><td> 5289</td><td>2584</td><td> 2971</td><td>2572</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td> 4</td><td>6</td><td>0</td><td>0</td><td>17</td><td>1</td><td> 27</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CQ-5331-01A</th><td> 1465</td><td> 0</td><td>2612</td><td>1027</td><td> 766</td><td>1084</td><td>14982</td><td>5098</td><td> 7356</td><td>4672</td><td>⋯</td><td>0</td><td>1</td><td>1</td><td> 2</td><td>1</td><td>0</td><td>0</td><td>18</td><td>1</td><td> 58</td></tr>\n",
       "\t<tr><th scope=row>TCGA-BB-8601-01A</th><td> 1630</td><td> 1</td><td>1227</td><td> 764</td><td> 687</td><td>  42</td><td>  357</td><td>1270</td><td>19713</td><td>1255</td><td>⋯</td><td>1</td><td>0</td><td>0</td><td> 3</td><td>0</td><td>0</td><td>0</td><td> 6</td><td>0</td><td> 40</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-A45W-01A</th><td> 2215</td><td> 0</td><td>1139</td><td> 526</td><td> 464</td><td>1024</td><td> 1911</td><td>1741</td><td> 8343</td><td>1061</td><td>⋯</td><td>1</td><td>2</td><td>1</td><td> 3</td><td>4</td><td>0</td><td>0</td><td> 0</td><td>0</td><td> 43</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CQ-7063-01A</th><td>  724</td><td> 0</td><td>1220</td><td> 461</td><td> 235</td><td> 668</td><td> 4934</td><td>1323</td><td> 1859</td><td>1229</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td> 1</td><td>1</td><td>0</td><td>0</td><td> 6</td><td>0</td><td> 10</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-5373-01A</th><td>  718</td><td> 0</td><td>1162</td><td> 577</td><td> 232</td><td> 475</td><td> 6444</td><td>2164</td><td> 2870</td><td>1650</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td> 1</td><td>1</td><td>0</td><td>0</td><td>10</td><td>0</td><td>  8</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-A45T-01A</th><td> 2120</td><td> 3</td><td>2252</td><td> 614</td><td> 340</td><td> 700</td><td> 4178</td><td>1998</td><td> 1845</td><td>1197</td><td>⋯</td><td>0</td><td>4</td><td>0</td><td> 0</td><td>1</td><td>0</td><td>0</td><td> 3</td><td>0</td><td> 25</td></tr>\n",
       "\t<tr><th scope=row>TCGA-HD-A4C1-01A</th><td> 1273</td><td> 2</td><td>1793</td><td> 646</td><td> 461</td><td> 238</td><td> 4564</td><td>1802</td><td> 2617</td><td>1129</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td> 2</td><td>0</td><td>0</td><td>0</td><td>14</td><td>0</td><td>  2</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7438-11A</th><td> 4370</td><td> 3</td><td>2064</td><td> 648</td><td> 367</td><td> 444</td><td> 3991</td><td>1808</td><td> 3503</td><td>1599</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td> 0</td><td>0</td><td>0</td><td>0</td><td> 9</td><td>0</td><td> 32</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-5444-01A</th><td> 1011</td><td> 0</td><td>1488</td><td> 627</td><td> 366</td><td> 607</td><td> 5459</td><td>1695</td><td> 1224</td><td>1192</td><td>⋯</td><td>0</td><td>6</td><td>0</td><td> 0</td><td>1</td><td>0</td><td>0</td><td> 8</td><td>0</td><td> 36</td></tr>\n",
       "\t<tr><th scope=row>TCGA-BA-5556-01A</th><td> 1646</td><td> 1</td><td>2146</td><td> 763</td><td> 538</td><td> 967</td><td> 9401</td><td>2521</td><td> 3916</td><td>2173</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td> 1</td><td>1</td><td>0</td><td>0</td><td>24</td><td>0</td><td> 13</td></tr>\n",
       "\t<tr><th scope=row>TCGA-P3-A6SX-01A</th><td> 1421</td><td> 0</td><td>2413</td><td> 794</td><td> 986</td><td>  76</td><td>  563</td><td>2652</td><td> 1788</td><td>1105</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td> 0</td><td>0</td><td>0</td><td>0</td><td>17</td><td>0</td><td> 19</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7242-11A</th><td> 9952</td><td> 9</td><td>2403</td><td> 832</td><td> 437</td><td>1000</td><td> 6336</td><td>1563</td><td> 4157</td><td>1589</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td> 6</td><td>0</td><td>0</td><td>0</td><td> 7</td><td>0</td><td> 12</td></tr>\n",
       "\t<tr><th scope=row>TCGA-DQ-7592-01A</th><td> 2923</td><td> 0</td><td>2507</td><td> 794</td><td> 650</td><td> 484</td><td> 9116</td><td>3996</td><td> 4762</td><td>3113</td><td>⋯</td><td>0</td><td>5</td><td>1</td><td> 0</td><td>1</td><td>0</td><td>0</td><td>23</td><td>1</td><td> 30</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6937-01A</th><td> 1232</td><td> 2</td><td>1212</td><td> 503</td><td> 210</td><td> 286</td><td>  324</td><td>1607</td><td>  866</td><td>1250</td><td>⋯</td><td>0</td><td>2</td><td>0</td><td> 1</td><td>0</td><td>0</td><td>0</td><td> 3</td><td>0</td><td>111</td></tr>\n",
       "\t<tr><th scope=row>TCGA-QK-A8ZB-01A</th><td> 2332</td><td> 0</td><td>3280</td><td> 642</td><td> 507</td><td> 491</td><td> 5042</td><td>3292</td><td> 2676</td><td>2995</td><td>⋯</td><td>0</td><td>9</td><td>0</td><td>11</td><td>3</td><td>0</td><td>0</td><td> 1</td><td>0</td><td> 24</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7432-01A</th><td> 2032</td><td> 0</td><td>2069</td><td> 434</td><td>1081</td><td> 105</td><td> 3398</td><td>3988</td><td> 4089</td><td>2119</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td> 1</td><td>0</td><td>0</td><td>0</td><td>13</td><td>0</td><td>  4</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7089-01A</th><td> 3005</td><td> 0</td><td>2056</td><td> 601</td><td> 504</td><td> 392</td><td> 3379</td><td>3651</td><td> 2524</td><td>1731</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td> 2</td><td>0</td><td>0</td><td>0</td><td>18</td><td>0</td><td> 15</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6939-11A</th><td> 1612</td><td>53</td><td> 729</td><td> 488</td><td>  45</td><td> 155</td><td>10545</td><td>1223</td><td> 1011</td><td> 492</td><td>⋯</td><td>0</td><td>3</td><td>0</td><td> 0</td><td>3</td><td>1</td><td>0</td><td> 7</td><td>0</td><td> 68</td></tr>\n",
       "\t<tr><th scope=row>TCGA-BA-4075-01A</th><td> 2950</td><td> 1</td><td>5510</td><td> 355</td><td> 710</td><td> 306</td><td> 2114</td><td>2328</td><td> 2450</td><td>2342</td><td>⋯</td><td>0</td><td>3</td><td>1</td><td> 1</td><td>0</td><td>0</td><td>0</td><td>20</td><td>0</td><td> 10</td></tr>\n",
       "\t<tr><th scope=row>TCGA-T3-A92M-01A</th><td> 1679</td><td> 0</td><td>2430</td><td> 624</td><td> 759</td><td> 379</td><td> 2443</td><td>2379</td><td> 1900</td><td>1833</td><td>⋯</td><td>0</td><td>8</td><td>0</td><td> 3</td><td>1</td><td>0</td><td>0</td><td>12</td><td>0</td><td>113</td></tr>\n",
       "\t<tr><th scope=row>⋮</th><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋱</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7430-01A</th><td> 3632</td><td> 0</td><td>2857</td><td> 362</td><td> 389</td><td> 136</td><td> 606</td><td>3344</td><td>18448</td><td>1312</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>3</td><td>0</td><td>0</td><td>0</td><td>35</td><td>0</td><td> 4</td></tr>\n",
       "\t<tr><th scope=row>TCGA-D6-A74Q-01A</th><td> 2368</td><td> 0</td><td>3792</td><td> 765</td><td> 541</td><td> 307</td><td>1291</td><td>4462</td><td> 2878</td><td> 985</td><td>⋯</td><td>0</td><td>3</td><td>0</td><td>1</td><td>6</td><td>5</td><td>0</td><td>18</td><td>0</td><td>26</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7255-01A</th><td> 5443</td><td> 0</td><td>3542</td><td> 884</td><td> 979</td><td> 135</td><td>5880</td><td>5834</td><td> 2829</td><td>4707</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>21</td><td>0</td><td>19</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CQ-6223-01A</th><td> 1406</td><td> 1</td><td>1875</td><td> 623</td><td> 453</td><td> 555</td><td>3190</td><td>2858</td><td> 4875</td><td>1946</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td>1</td><td>0</td><td>0</td><td>0</td><td>17</td><td>0</td><td>50</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-A460-01A</th><td> 1049</td><td> 0</td><td>2070</td><td> 895</td><td> 853</td><td> 985</td><td>3735</td><td>1697</td><td> 7706</td><td>2500</td><td>⋯</td><td>0</td><td>6</td><td>0</td><td>2</td><td>4</td><td>0</td><td>0</td><td>10</td><td>0</td><td>25</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7261-01A</th><td> 2048</td><td> 2</td><td>1007</td><td> 750</td><td> 487</td><td> 493</td><td>1735</td><td>2226</td><td>13697</td><td>1659</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>1</td><td>0</td><td>0</td><td>11</td><td>1</td><td>21</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-4736-01A</th><td>  980</td><td>35</td><td>2072</td><td> 613</td><td> 287</td><td>2004</td><td>6050</td><td>3235</td><td>15570</td><td>1748</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td>1</td><td>2</td><td>0</td><td>0</td><td>12</td><td>1</td><td>20</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CR-7404-01A</th><td> 2646</td><td>18</td><td>2293</td><td>1259</td><td>1067</td><td>1147</td><td>6266</td><td>3687</td><td> 8930</td><td>3086</td><td>⋯</td><td>0</td><td>4</td><td>0</td><td>5</td><td>2</td><td>0</td><td>0</td><td> 6</td><td>0</td><td>99</td></tr>\n",
       "\t<tr><th scope=row>TCGA-UF-A719-01A</th><td> 5193</td><td> 0</td><td>1751</td><td>1275</td><td>1325</td><td> 203</td><td> 352</td><td>3428</td><td>27455</td><td>2397</td><td>⋯</td><td>0</td><td>2</td><td>0</td><td>1</td><td>1</td><td>0</td><td>0</td><td> 3</td><td>0</td><td>81</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7236-01A</th><td> 2366</td><td> 0</td><td>1862</td><td> 392</td><td> 367</td><td> 429</td><td>5933</td><td>2311</td><td> 4241</td><td>3022</td><td>⋯</td><td>0</td><td>1</td><td>1</td><td>0</td><td>1</td><td>0</td><td>0</td><td>32</td><td>0</td><td>22</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6951-01A</th><td> 3280</td><td> 1</td><td>1973</td><td> 904</td><td> 300</td><td> 111</td><td> 736</td><td>1844</td><td>15010</td><td>1314</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>19</td><td>0</td><td>44</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-4728-01A</th><td> 1136</td><td> 1</td><td>1739</td><td> 668</td><td> 347</td><td>2618</td><td>5170</td><td>2296</td><td> 2764</td><td>1537</td><td>⋯</td><td>0</td><td>3</td><td>1</td><td>1</td><td>5</td><td>0</td><td>0</td><td>10</td><td>1</td><td>12</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7090-01A</th><td> 1050</td><td> 3</td><td>1520</td><td> 464</td><td> 406</td><td> 698</td><td>2617</td><td>2863</td><td> 2464</td><td>1940</td><td>⋯</td><td>0</td><td>5</td><td>0</td><td>0</td><td>1</td><td>0</td><td>0</td><td>15</td><td>0</td><td> 8</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-5979-01A</th><td> 1416</td><td> 0</td><td>1383</td><td> 594</td><td> 517</td><td> 160</td><td>6088</td><td>5182</td><td> 3640</td><td>1324</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td> 8</td><td>0</td><td>17</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CQ-7069-01A</th><td>  728</td><td> 0</td><td>1603</td><td> 255</td><td> 165</td><td> 200</td><td>1027</td><td>1372</td><td>  796</td><td>1018</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>1</td><td>0</td><td>0</td><td>0</td><td> 6</td><td>0</td><td>10</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-4733-01A</th><td>  727</td><td> 1</td><td>1151</td><td> 481</td><td> 463</td><td> 934</td><td>6624</td><td>3854</td><td> 2812</td><td>1833</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>7</td><td>0</td><td>0</td><td> 9</td><td>0</td><td>10</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CR-7390-01A</th><td> 1995</td><td> 1</td><td>1561</td><td> 730</td><td> 594</td><td> 382</td><td>1708</td><td>2618</td><td>24128</td><td>2214</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td>1</td><td>0</td><td>0</td><td>0</td><td>15</td><td>0</td><td>32</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-A45X-01A</th><td> 1795</td><td> 1</td><td>1913</td><td> 977</td><td> 516</td><td> 211</td><td>1407</td><td>1556</td><td> 2578</td><td>1250</td><td>⋯</td><td>0</td><td>5</td><td>0</td><td>3</td><td>0</td><td>0</td><td>0</td><td> 9</td><td>0</td><td>14</td></tr>\n",
       "\t<tr><th scope=row>TCGA-IQ-A6SH-01A</th><td> 1428</td><td> 0</td><td>2404</td><td> 393</td><td> 334</td><td> 166</td><td>6937</td><td>3944</td><td> 7729</td><td>1394</td><td>⋯</td><td>0</td><td>3</td><td>0</td><td>0</td><td>3</td><td>1</td><td>0</td><td> 9</td><td>0</td><td>44</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6962-11A</th><td>11809</td><td> 4</td><td>1623</td><td> 981</td><td> 299</td><td> 281</td><td>9783</td><td>1691</td><td> 2135</td><td>1369</td><td>⋯</td><td>0</td><td>2</td><td>0</td><td>0</td><td>2</td><td>0</td><td>0</td><td> 8</td><td>0</td><td>41</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6960-11A</th><td> 3340</td><td> 0</td><td>1388</td><td> 608</td><td> 206</td><td> 304</td><td>6363</td><td>1242</td><td> 2100</td><td>1369</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td>2</td><td>1</td><td>0</td><td>0</td><td>12</td><td>0</td><td>19</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-A464-01A</th><td>  929</td><td> 2</td><td>2332</td><td> 472</td><td> 386</td><td> 331</td><td>7799</td><td>3028</td><td> 2494</td><td>1711</td><td>⋯</td><td>0</td><td>3</td><td>1</td><td>2</td><td>3</td><td>0</td><td>1</td><td> 1</td><td>0</td><td>46</td></tr>\n",
       "\t<tr><th scope=row>TCGA-C9-A47Z-01A</th><td> 1707</td><td> 0</td><td>1926</td><td> 410</td><td> 210</td><td> 134</td><td>1264</td><td>1356</td><td> 3710</td><td>1671</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>4</td><td>0</td><td>0</td><td>0</td><td>35</td><td>0</td><td>14</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-6010-01A</th><td> 2218</td><td> 0</td><td>1574</td><td> 852</td><td> 729</td><td> 550</td><td>5558</td><td>2921</td><td> 8749</td><td>1596</td><td>⋯</td><td>0</td><td>2</td><td>0</td><td>0</td><td>2</td><td>0</td><td>0</td><td>17</td><td>0</td><td>54</td></tr>\n",
       "\t<tr><th scope=row>TCGA-WA-A7GZ-11A</th><td> 2537</td><td>41</td><td>1171</td><td> 557</td><td> 127</td><td> 165</td><td>4651</td><td> 647</td><td> 3029</td><td> 848</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td>0</td><td>2</td><td>0</td><td>0</td><td>16</td><td>0</td><td>38</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7235-01A</th><td>  492</td><td> 0</td><td> 976</td><td> 376</td><td> 363</td><td> 488</td><td>5178</td><td>2138</td><td>20007</td><td>4131</td><td>⋯</td><td>0</td><td>2</td><td>2</td><td>1</td><td>0</td><td>0</td><td>0</td><td> 8</td><td>0</td><td>60</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CX-7086-01A</th><td> 2741</td><td> 0</td><td>1952</td><td>1003</td><td>1103</td><td> 214</td><td>1809</td><td>2639</td><td>13623</td><td>2530</td><td>⋯</td><td>2</td><td>2</td><td>0</td><td>1</td><td>0</td><td>1</td><td>0</td><td>11</td><td>0</td><td>77</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6935-11A</th><td> 8492</td><td> 3</td><td>1578</td><td> 818</td><td> 281</td><td> 419</td><td>7368</td><td>1355</td><td> 2276</td><td>1583</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td>1</td><td>0</td><td>0</td><td>0</td><td>12</td><td>0</td><td>19</td></tr>\n",
       "\t<tr><th scope=row>TCGA-P3-A6SW-01A</th><td>  770</td><td> 1</td><td>1569</td><td> 620</td><td> 591</td><td> 462</td><td>2082</td><td>1603</td><td>31675</td><td>1473</td><td>⋯</td><td>0</td><td>0</td><td>2</td><td>1</td><td>1</td><td>0</td><td>0</td><td> 0</td><td>1</td><td>22</td></tr>\n",
       "\t<tr><th scope=row>TCGA-HD-A6HZ-01A</th><td>  923</td><td> 0</td><td>1183</td><td> 607</td><td> 344</td><td> 925</td><td>2482</td><td>1769</td><td> 3949</td><td> 899</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td>0</td><td>1</td><td>0</td><td>0</td><td>11</td><td>1</td><td>40</td></tr>\n",
       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "A matrix: 546 × 38929 of type dbl\n",
       "\\begin{tabular}{r|lllllllllllllllllllll}\n",
       "  & TSPAN6 & TNMD & DPM1 & SCYL3 & C1orf112 & FGR & CFH & FUCA2 & GCLC & NFYA & ⋯ & LINC00550 & LINC01394 & LINC00602 & MIR1291 & LINC00891 & PAUPAR & GIMAP1-GIMAP5 & LINC02246 & HERC2P7 & LINC01144\\\\\n",
       "\\hline\n",
       "\tTCGA-BB-4224-01A &  2237 &  2 & 1606 & 1063 & 1208 &  256 &   177 & 2371 &  2741 & 2515 & ⋯ & 6 & 7 & 0 &  2 & 0 & 6 & 0 & 16 & 0 & 144\\\\\n",
       "\tTCGA-H7-7774-01A &  2740 &  0 & 1691 &  803 &  317 &  330 &  5472 & 2316 &  8370 &  816 & ⋯ & 0 & 1 & 0 &  0 & 2 & 0 & 0 &  6 & 0 &  23\\\\\n",
       "\tTCGA-CV-6943-01A &  2686 &  0 & 1649 &  917 &  402 & 1535 & 15358 & 3490 &  4671 & 2080 & ⋯ & 0 & 4 & 0 &  2 & 4 & 1 & 0 & 38 & 0 &  18\\\\\n",
       "\tTCGA-CN-5374-01A &  2086 &  1 & 2333 & 1288 & 1105 &  639 &  5565 & 2065 &  2902 & 1777 & ⋯ & 0 & 0 & 1 &  0 & 3 & 0 & 0 &  4 & 0 &  31\\\\\n",
       "\tTCGA-CQ-6227-01A & 10167 &  9 & 3021 &  537 &  459 &  362 &  6963 & 4883 &  3140 & 2448 & ⋯ & 1 & 3 & 0 &  0 & 2 & 0 & 0 & 15 & 0 &  24\\\\\n",
       "\tTCGA-CV-6959-01A &  1154 &  6 & 2766 &  527 &  747 &  906 & 12856 & 6120 &  7448 & 3527 & ⋯ & 0 & 1 & 0 &  1 & 3 & 1 & 0 & 19 & 1 &  15\\\\\n",
       "\tTCGA-F7-A61V-01A &  1978 &  1 & 1762 &  482 &  331 &  147 &   793 & 2364 &  2827 & 1159 & ⋯ & 0 & 0 & 0 &  1 & 1 & 0 & 0 & 15 & 0 &  20\\\\\n",
       "\tTCGA-CV-7413-01A &  1930 &  1 & 1668 &  671 &  476 &  477 &  3669 & 3366 &  2324 & 1459 & ⋯ & 0 & 3 & 0 &  0 & 1 & 0 & 0 & 19 & 1 &  23\\\\\n",
       "\tTCGA-CV-7247-01A &  1066 &  1 & 1760 &  600 &  874 &  204 &  2791 & 1837 &  9779 & 1916 & ⋯ & 0 & 0 & 0 &  0 & 1 & 0 & 0 & 17 & 1 &  43\\\\\n",
       "\tTCGA-CR-5249-01A &  2538 &  0 & 1268 & 1066 &  950 &  924 &  5289 & 2584 &  2971 & 2572 & ⋯ & 0 & 0 & 0 &  4 & 6 & 0 & 0 & 17 & 1 &  27\\\\\n",
       "\tTCGA-CQ-5331-01A &  1465 &  0 & 2612 & 1027 &  766 & 1084 & 14982 & 5098 &  7356 & 4672 & ⋯ & 0 & 1 & 1 &  2 & 1 & 0 & 0 & 18 & 1 &  58\\\\\n",
       "\tTCGA-BB-8601-01A &  1630 &  1 & 1227 &  764 &  687 &   42 &   357 & 1270 & 19713 & 1255 & ⋯ & 1 & 0 & 0 &  3 & 0 & 0 & 0 &  6 & 0 &  40\\\\\n",
       "\tTCGA-CV-A45W-01A &  2215 &  0 & 1139 &  526 &  464 & 1024 &  1911 & 1741 &  8343 & 1061 & ⋯ & 1 & 2 & 1 &  3 & 4 & 0 & 0 &  0 & 0 &  43\\\\\n",
       "\tTCGA-CQ-7063-01A &   724 &  0 & 1220 &  461 &  235 &  668 &  4934 & 1323 &  1859 & 1229 & ⋯ & 0 & 0 & 0 &  1 & 1 & 0 & 0 &  6 & 0 &  10\\\\\n",
       "\tTCGA-CN-5373-01A &   718 &  0 & 1162 &  577 &  232 &  475 &  6444 & 2164 &  2870 & 1650 & ⋯ & 0 & 0 & 0 &  1 & 1 & 0 & 0 & 10 & 0 &   8\\\\\n",
       "\tTCGA-CV-A45T-01A &  2120 &  3 & 2252 &  614 &  340 &  700 &  4178 & 1998 &  1845 & 1197 & ⋯ & 0 & 4 & 0 &  0 & 1 & 0 & 0 &  3 & 0 &  25\\\\\n",
       "\tTCGA-HD-A4C1-01A &  1273 &  2 & 1793 &  646 &  461 &  238 &  4564 & 1802 &  2617 & 1129 & ⋯ & 0 & 1 & 0 &  2 & 0 & 0 & 0 & 14 & 0 &   2\\\\\n",
       "\tTCGA-CV-7438-11A &  4370 &  3 & 2064 &  648 &  367 &  444 &  3991 & 1808 &  3503 & 1599 & ⋯ & 0 & 0 & 0 &  0 & 0 & 0 & 0 &  9 & 0 &  32\\\\\n",
       "\tTCGA-CV-5444-01A &  1011 &  0 & 1488 &  627 &  366 &  607 &  5459 & 1695 &  1224 & 1192 & ⋯ & 0 & 6 & 0 &  0 & 1 & 0 & 0 &  8 & 0 &  36\\\\\n",
       "\tTCGA-BA-5556-01A &  1646 &  1 & 2146 &  763 &  538 &  967 &  9401 & 2521 &  3916 & 2173 & ⋯ & 0 & 1 & 0 &  1 & 1 & 0 & 0 & 24 & 0 &  13\\\\\n",
       "\tTCGA-P3-A6SX-01A &  1421 &  0 & 2413 &  794 &  986 &   76 &   563 & 2652 &  1788 & 1105 & ⋯ & 0 & 0 & 0 &  0 & 0 & 0 & 0 & 17 & 0 &  19\\\\\n",
       "\tTCGA-CV-7242-11A &  9952 &  9 & 2403 &  832 &  437 & 1000 &  6336 & 1563 &  4157 & 1589 & ⋯ & 0 & 0 & 0 &  6 & 0 & 0 & 0 &  7 & 0 &  12\\\\\n",
       "\tTCGA-DQ-7592-01A &  2923 &  0 & 2507 &  794 &  650 &  484 &  9116 & 3996 &  4762 & 3113 & ⋯ & 0 & 5 & 1 &  0 & 1 & 0 & 0 & 23 & 1 &  30\\\\\n",
       "\tTCGA-CV-6937-01A &  1232 &  2 & 1212 &  503 &  210 &  286 &   324 & 1607 &   866 & 1250 & ⋯ & 0 & 2 & 0 &  1 & 0 & 0 & 0 &  3 & 0 & 111\\\\\n",
       "\tTCGA-QK-A8ZB-01A &  2332 &  0 & 3280 &  642 &  507 &  491 &  5042 & 3292 &  2676 & 2995 & ⋯ & 0 & 9 & 0 & 11 & 3 & 0 & 0 &  1 & 0 &  24\\\\\n",
       "\tTCGA-CV-7432-01A &  2032 &  0 & 2069 &  434 & 1081 &  105 &  3398 & 3988 &  4089 & 2119 & ⋯ & 0 & 1 & 0 &  1 & 0 & 0 & 0 & 13 & 0 &   4\\\\\n",
       "\tTCGA-CV-7089-01A &  3005 &  0 & 2056 &  601 &  504 &  392 &  3379 & 3651 &  2524 & 1731 & ⋯ & 0 & 0 & 0 &  2 & 0 & 0 & 0 & 18 & 0 &  15\\\\\n",
       "\tTCGA-CV-6939-11A &  1612 & 53 &  729 &  488 &   45 &  155 & 10545 & 1223 &  1011 &  492 & ⋯ & 0 & 3 & 0 &  0 & 3 & 1 & 0 &  7 & 0 &  68\\\\\n",
       "\tTCGA-BA-4075-01A &  2950 &  1 & 5510 &  355 &  710 &  306 &  2114 & 2328 &  2450 & 2342 & ⋯ & 0 & 3 & 1 &  1 & 0 & 0 & 0 & 20 & 0 &  10\\\\\n",
       "\tTCGA-T3-A92M-01A &  1679 &  0 & 2430 &  624 &  759 &  379 &  2443 & 2379 &  1900 & 1833 & ⋯ & 0 & 8 & 0 &  3 & 1 & 0 & 0 & 12 & 0 & 113\\\\\n",
       "\t⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋱ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮\\\\\n",
       "\tTCGA-CV-7430-01A &  3632 &  0 & 2857 &  362 &  389 &  136 &  606 & 3344 & 18448 & 1312 & ⋯ & 0 & 0 & 0 & 3 & 0 & 0 & 0 & 35 & 0 &  4\\\\\n",
       "\tTCGA-D6-A74Q-01A &  2368 &  0 & 3792 &  765 &  541 &  307 & 1291 & 4462 &  2878 &  985 & ⋯ & 0 & 3 & 0 & 1 & 6 & 5 & 0 & 18 & 0 & 26\\\\\n",
       "\tTCGA-CV-7255-01A &  5443 &  0 & 3542 &  884 &  979 &  135 & 5880 & 5834 &  2829 & 4707 & ⋯ & 0 & 1 & 0 & 0 & 0 & 0 & 0 & 21 & 0 & 19\\\\\n",
       "\tTCGA-CQ-6223-01A &  1406 &  1 & 1875 &  623 &  453 &  555 & 3190 & 2858 &  4875 & 1946 & ⋯ & 0 & 1 & 0 & 1 & 0 & 0 & 0 & 17 & 0 & 50\\\\\n",
       "\tTCGA-CV-A460-01A &  1049 &  0 & 2070 &  895 &  853 &  985 & 3735 & 1697 &  7706 & 2500 & ⋯ & 0 & 6 & 0 & 2 & 4 & 0 & 0 & 10 & 0 & 25\\\\\n",
       "\tTCGA-CV-7261-01A &  2048 &  2 & 1007 &  750 &  487 &  493 & 1735 & 2226 & 13697 & 1659 & ⋯ & 0 & 0 & 0 & 0 & 1 & 0 & 0 & 11 & 1 & 21\\\\\n",
       "\tTCGA-CN-4736-01A &   980 & 35 & 2072 &  613 &  287 & 2004 & 6050 & 3235 & 15570 & 1748 & ⋯ & 0 & 1 & 0 & 1 & 2 & 0 & 0 & 12 & 1 & 20\\\\\n",
       "\tTCGA-CR-7404-01A &  2646 & 18 & 2293 & 1259 & 1067 & 1147 & 6266 & 3687 &  8930 & 3086 & ⋯ & 0 & 4 & 0 & 5 & 2 & 0 & 0 &  6 & 0 & 99\\\\\n",
       "\tTCGA-UF-A719-01A &  5193 &  0 & 1751 & 1275 & 1325 &  203 &  352 & 3428 & 27455 & 2397 & ⋯ & 0 & 2 & 0 & 1 & 1 & 0 & 0 &  3 & 0 & 81\\\\\n",
       "\tTCGA-CV-7236-01A &  2366 &  0 & 1862 &  392 &  367 &  429 & 5933 & 2311 &  4241 & 3022 & ⋯ & 0 & 1 & 1 & 0 & 1 & 0 & 0 & 32 & 0 & 22\\\\\n",
       "\tTCGA-CV-6951-01A &  3280 &  1 & 1973 &  904 &  300 &  111 &  736 & 1844 & 15010 & 1314 & ⋯ & 0 & 1 & 0 & 0 & 0 & 0 & 0 & 19 & 0 & 44\\\\\n",
       "\tTCGA-CN-4728-01A &  1136 &  1 & 1739 &  668 &  347 & 2618 & 5170 & 2296 &  2764 & 1537 & ⋯ & 0 & 3 & 1 & 1 & 5 & 0 & 0 & 10 & 1 & 12\\\\\n",
       "\tTCGA-CV-7090-01A &  1050 &  3 & 1520 &  464 &  406 &  698 & 2617 & 2863 &  2464 & 1940 & ⋯ & 0 & 5 & 0 & 0 & 1 & 0 & 0 & 15 & 0 &  8\\\\\n",
       "\tTCGA-CV-5979-01A &  1416 &  0 & 1383 &  594 &  517 &  160 & 6088 & 5182 &  3640 & 1324 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 &  8 & 0 & 17\\\\\n",
       "\tTCGA-CQ-7069-01A &   728 &  0 & 1603 &  255 &  165 &  200 & 1027 & 1372 &   796 & 1018 & ⋯ & 0 & 0 & 0 & 1 & 0 & 0 & 0 &  6 & 0 & 10\\\\\n",
       "\tTCGA-CN-4733-01A &   727 &  1 & 1151 &  481 &  463 &  934 & 6624 & 3854 &  2812 & 1833 & ⋯ & 0 & 0 & 0 & 0 & 7 & 0 & 0 &  9 & 0 & 10\\\\\n",
       "\tTCGA-CR-7390-01A &  1995 &  1 & 1561 &  730 &  594 &  382 & 1708 & 2618 & 24128 & 2214 & ⋯ & 0 & 1 & 0 & 1 & 0 & 0 & 0 & 15 & 0 & 32\\\\\n",
       "\tTCGA-CV-A45X-01A &  1795 &  1 & 1913 &  977 &  516 &  211 & 1407 & 1556 &  2578 & 1250 & ⋯ & 0 & 5 & 0 & 3 & 0 & 0 & 0 &  9 & 0 & 14\\\\\n",
       "\tTCGA-IQ-A6SH-01A &  1428 &  0 & 2404 &  393 &  334 &  166 & 6937 & 3944 &  7729 & 1394 & ⋯ & 0 & 3 & 0 & 0 & 3 & 1 & 0 &  9 & 0 & 44\\\\\n",
       "\tTCGA-CV-6962-11A & 11809 &  4 & 1623 &  981 &  299 &  281 & 9783 & 1691 &  2135 & 1369 & ⋯ & 0 & 2 & 0 & 0 & 2 & 0 & 0 &  8 & 0 & 41\\\\\n",
       "\tTCGA-CV-6960-11A &  3340 &  0 & 1388 &  608 &  206 &  304 & 6363 & 1242 &  2100 & 1369 & ⋯ & 0 & 1 & 0 & 2 & 1 & 0 & 0 & 12 & 0 & 19\\\\\n",
       "\tTCGA-CV-A464-01A &   929 &  2 & 2332 &  472 &  386 &  331 & 7799 & 3028 &  2494 & 1711 & ⋯ & 0 & 3 & 1 & 2 & 3 & 0 & 1 &  1 & 0 & 46\\\\\n",
       "\tTCGA-C9-A47Z-01A &  1707 &  0 & 1926 &  410 &  210 &  134 & 1264 & 1356 &  3710 & 1671 & ⋯ & 0 & 0 & 0 & 4 & 0 & 0 & 0 & 35 & 0 & 14\\\\\n",
       "\tTCGA-CN-6010-01A &  2218 &  0 & 1574 &  852 &  729 &  550 & 5558 & 2921 &  8749 & 1596 & ⋯ & 0 & 2 & 0 & 0 & 2 & 0 & 0 & 17 & 0 & 54\\\\\n",
       "\tTCGA-WA-A7GZ-11A &  2537 & 41 & 1171 &  557 &  127 &  165 & 4651 &  647 &  3029 &  848 & ⋯ & 0 & 1 & 0 & 0 & 2 & 0 & 0 & 16 & 0 & 38\\\\\n",
       "\tTCGA-CV-7235-01A &   492 &  0 &  976 &  376 &  363 &  488 & 5178 & 2138 & 20007 & 4131 & ⋯ & 0 & 2 & 2 & 1 & 0 & 0 & 0 &  8 & 0 & 60\\\\\n",
       "\tTCGA-CX-7086-01A &  2741 &  0 & 1952 & 1003 & 1103 &  214 & 1809 & 2639 & 13623 & 2530 & ⋯ & 2 & 2 & 0 & 1 & 0 & 1 & 0 & 11 & 0 & 77\\\\\n",
       "\tTCGA-CV-6935-11A &  8492 &  3 & 1578 &  818 &  281 &  419 & 7368 & 1355 &  2276 & 1583 & ⋯ & 0 & 1 & 0 & 1 & 0 & 0 & 0 & 12 & 0 & 19\\\\\n",
       "\tTCGA-P3-A6SW-01A &   770 &  1 & 1569 &  620 &  591 &  462 & 2082 & 1603 & 31675 & 1473 & ⋯ & 0 & 0 & 2 & 1 & 1 & 0 & 0 &  0 & 1 & 22\\\\\n",
       "\tTCGA-HD-A6HZ-01A &   923 &  0 & 1183 &  607 &  344 &  925 & 2482 & 1769 &  3949 &  899 & ⋯ & 0 & 1 & 0 & 0 & 1 & 0 & 0 & 11 & 1 & 40\\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "A matrix: 546 × 38929 of type dbl\n",
       "\n",
       "| <!--/--> | TSPAN6 | TNMD | DPM1 | SCYL3 | C1orf112 | FGR | CFH | FUCA2 | GCLC | NFYA | ⋯ | LINC00550 | LINC01394 | LINC00602 | MIR1291 | LINC00891 | PAUPAR | GIMAP1-GIMAP5 | LINC02246 | HERC2P7 | LINC01144 |\n",
       "|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|\n",
       "| TCGA-BB-4224-01A |  2237 |  2 | 1606 | 1063 | 1208 |  256 |   177 | 2371 |  2741 | 2515 | ⋯ | 6 | 7 | 0 |  2 | 0 | 6 | 0 | 16 | 0 | 144 |\n",
       "| TCGA-H7-7774-01A |  2740 |  0 | 1691 |  803 |  317 |  330 |  5472 | 2316 |  8370 |  816 | ⋯ | 0 | 1 | 0 |  0 | 2 | 0 | 0 |  6 | 0 |  23 |\n",
       "| TCGA-CV-6943-01A |  2686 |  0 | 1649 |  917 |  402 | 1535 | 15358 | 3490 |  4671 | 2080 | ⋯ | 0 | 4 | 0 |  2 | 4 | 1 | 0 | 38 | 0 |  18 |\n",
       "| TCGA-CN-5374-01A |  2086 |  1 | 2333 | 1288 | 1105 |  639 |  5565 | 2065 |  2902 | 1777 | ⋯ | 0 | 0 | 1 |  0 | 3 | 0 | 0 |  4 | 0 |  31 |\n",
       "| TCGA-CQ-6227-01A | 10167 |  9 | 3021 |  537 |  459 |  362 |  6963 | 4883 |  3140 | 2448 | ⋯ | 1 | 3 | 0 |  0 | 2 | 0 | 0 | 15 | 0 |  24 |\n",
       "| TCGA-CV-6959-01A |  1154 |  6 | 2766 |  527 |  747 |  906 | 12856 | 6120 |  7448 | 3527 | ⋯ | 0 | 1 | 0 |  1 | 3 | 1 | 0 | 19 | 1 |  15 |\n",
       "| TCGA-F7-A61V-01A |  1978 |  1 | 1762 |  482 |  331 |  147 |   793 | 2364 |  2827 | 1159 | ⋯ | 0 | 0 | 0 |  1 | 1 | 0 | 0 | 15 | 0 |  20 |\n",
       "| TCGA-CV-7413-01A |  1930 |  1 | 1668 |  671 |  476 |  477 |  3669 | 3366 |  2324 | 1459 | ⋯ | 0 | 3 | 0 |  0 | 1 | 0 | 0 | 19 | 1 |  23 |\n",
       "| TCGA-CV-7247-01A |  1066 |  1 | 1760 |  600 |  874 |  204 |  2791 | 1837 |  9779 | 1916 | ⋯ | 0 | 0 | 0 |  0 | 1 | 0 | 0 | 17 | 1 |  43 |\n",
       "| TCGA-CR-5249-01A |  2538 |  0 | 1268 | 1066 |  950 |  924 |  5289 | 2584 |  2971 | 2572 | ⋯ | 0 | 0 | 0 |  4 | 6 | 0 | 0 | 17 | 1 |  27 |\n",
       "| TCGA-CQ-5331-01A |  1465 |  0 | 2612 | 1027 |  766 | 1084 | 14982 | 5098 |  7356 | 4672 | ⋯ | 0 | 1 | 1 |  2 | 1 | 0 | 0 | 18 | 1 |  58 |\n",
       "| TCGA-BB-8601-01A |  1630 |  1 | 1227 |  764 |  687 |   42 |   357 | 1270 | 19713 | 1255 | ⋯ | 1 | 0 | 0 |  3 | 0 | 0 | 0 |  6 | 0 |  40 |\n",
       "| TCGA-CV-A45W-01A |  2215 |  0 | 1139 |  526 |  464 | 1024 |  1911 | 1741 |  8343 | 1061 | ⋯ | 1 | 2 | 1 |  3 | 4 | 0 | 0 |  0 | 0 |  43 |\n",
       "| TCGA-CQ-7063-01A |   724 |  0 | 1220 |  461 |  235 |  668 |  4934 | 1323 |  1859 | 1229 | ⋯ | 0 | 0 | 0 |  1 | 1 | 0 | 0 |  6 | 0 |  10 |\n",
       "| TCGA-CN-5373-01A |   718 |  0 | 1162 |  577 |  232 |  475 |  6444 | 2164 |  2870 | 1650 | ⋯ | 0 | 0 | 0 |  1 | 1 | 0 | 0 | 10 | 0 |   8 |\n",
       "| TCGA-CV-A45T-01A |  2120 |  3 | 2252 |  614 |  340 |  700 |  4178 | 1998 |  1845 | 1197 | ⋯ | 0 | 4 | 0 |  0 | 1 | 0 | 0 |  3 | 0 |  25 |\n",
       "| TCGA-HD-A4C1-01A |  1273 |  2 | 1793 |  646 |  461 |  238 |  4564 | 1802 |  2617 | 1129 | ⋯ | 0 | 1 | 0 |  2 | 0 | 0 | 0 | 14 | 0 |   2 |\n",
       "| TCGA-CV-7438-11A |  4370 |  3 | 2064 |  648 |  367 |  444 |  3991 | 1808 |  3503 | 1599 | ⋯ | 0 | 0 | 0 |  0 | 0 | 0 | 0 |  9 | 0 |  32 |\n",
       "| TCGA-CV-5444-01A |  1011 |  0 | 1488 |  627 |  366 |  607 |  5459 | 1695 |  1224 | 1192 | ⋯ | 0 | 6 | 0 |  0 | 1 | 0 | 0 |  8 | 0 |  36 |\n",
       "| TCGA-BA-5556-01A |  1646 |  1 | 2146 |  763 |  538 |  967 |  9401 | 2521 |  3916 | 2173 | ⋯ | 0 | 1 | 0 |  1 | 1 | 0 | 0 | 24 | 0 |  13 |\n",
       "| TCGA-P3-A6SX-01A |  1421 |  0 | 2413 |  794 |  986 |   76 |   563 | 2652 |  1788 | 1105 | ⋯ | 0 | 0 | 0 |  0 | 0 | 0 | 0 | 17 | 0 |  19 |\n",
       "| TCGA-CV-7242-11A |  9952 |  9 | 2403 |  832 |  437 | 1000 |  6336 | 1563 |  4157 | 1589 | ⋯ | 0 | 0 | 0 |  6 | 0 | 0 | 0 |  7 | 0 |  12 |\n",
       "| TCGA-DQ-7592-01A |  2923 |  0 | 2507 |  794 |  650 |  484 |  9116 | 3996 |  4762 | 3113 | ⋯ | 0 | 5 | 1 |  0 | 1 | 0 | 0 | 23 | 1 |  30 |\n",
       "| TCGA-CV-6937-01A |  1232 |  2 | 1212 |  503 |  210 |  286 |   324 | 1607 |   866 | 1250 | ⋯ | 0 | 2 | 0 |  1 | 0 | 0 | 0 |  3 | 0 | 111 |\n",
       "| TCGA-QK-A8ZB-01A |  2332 |  0 | 3280 |  642 |  507 |  491 |  5042 | 3292 |  2676 | 2995 | ⋯ | 0 | 9 | 0 | 11 | 3 | 0 | 0 |  1 | 0 |  24 |\n",
       "| TCGA-CV-7432-01A |  2032 |  0 | 2069 |  434 | 1081 |  105 |  3398 | 3988 |  4089 | 2119 | ⋯ | 0 | 1 | 0 |  1 | 0 | 0 | 0 | 13 | 0 |   4 |\n",
       "| TCGA-CV-7089-01A |  3005 |  0 | 2056 |  601 |  504 |  392 |  3379 | 3651 |  2524 | 1731 | ⋯ | 0 | 0 | 0 |  2 | 0 | 0 | 0 | 18 | 0 |  15 |\n",
       "| TCGA-CV-6939-11A |  1612 | 53 |  729 |  488 |   45 |  155 | 10545 | 1223 |  1011 |  492 | ⋯ | 0 | 3 | 0 |  0 | 3 | 1 | 0 |  7 | 0 |  68 |\n",
       "| TCGA-BA-4075-01A |  2950 |  1 | 5510 |  355 |  710 |  306 |  2114 | 2328 |  2450 | 2342 | ⋯ | 0 | 3 | 1 |  1 | 0 | 0 | 0 | 20 | 0 |  10 |\n",
       "| TCGA-T3-A92M-01A |  1679 |  0 | 2430 |  624 |  759 |  379 |  2443 | 2379 |  1900 | 1833 | ⋯ | 0 | 8 | 0 |  3 | 1 | 0 | 0 | 12 | 0 | 113 |\n",
       "| ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋱ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ |\n",
       "| TCGA-CV-7430-01A |  3632 |  0 | 2857 |  362 |  389 |  136 |  606 | 3344 | 18448 | 1312 | ⋯ | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 35 | 0 |  4 |\n",
       "| TCGA-D6-A74Q-01A |  2368 |  0 | 3792 |  765 |  541 |  307 | 1291 | 4462 |  2878 |  985 | ⋯ | 0 | 3 | 0 | 1 | 6 | 5 | 0 | 18 | 0 | 26 |\n",
       "| TCGA-CV-7255-01A |  5443 |  0 | 3542 |  884 |  979 |  135 | 5880 | 5834 |  2829 | 4707 | ⋯ | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 21 | 0 | 19 |\n",
       "| TCGA-CQ-6223-01A |  1406 |  1 | 1875 |  623 |  453 |  555 | 3190 | 2858 |  4875 | 1946 | ⋯ | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 17 | 0 | 50 |\n",
       "| TCGA-CV-A460-01A |  1049 |  0 | 2070 |  895 |  853 |  985 | 3735 | 1697 |  7706 | 2500 | ⋯ | 0 | 6 | 0 | 2 | 4 | 0 | 0 | 10 | 0 | 25 |\n",
       "| TCGA-CV-7261-01A |  2048 |  2 | 1007 |  750 |  487 |  493 | 1735 | 2226 | 13697 | 1659 | ⋯ | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 11 | 1 | 21 |\n",
       "| TCGA-CN-4736-01A |   980 | 35 | 2072 |  613 |  287 | 2004 | 6050 | 3235 | 15570 | 1748 | ⋯ | 0 | 1 | 0 | 1 | 2 | 0 | 0 | 12 | 1 | 20 |\n",
       "| TCGA-CR-7404-01A |  2646 | 18 | 2293 | 1259 | 1067 | 1147 | 6266 | 3687 |  8930 | 3086 | ⋯ | 0 | 4 | 0 | 5 | 2 | 0 | 0 |  6 | 0 | 99 |\n",
       "| TCGA-UF-A719-01A |  5193 |  0 | 1751 | 1275 | 1325 |  203 |  352 | 3428 | 27455 | 2397 | ⋯ | 0 | 2 | 0 | 1 | 1 | 0 | 0 |  3 | 0 | 81 |\n",
       "| TCGA-CV-7236-01A |  2366 |  0 | 1862 |  392 |  367 |  429 | 5933 | 2311 |  4241 | 3022 | ⋯ | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 32 | 0 | 22 |\n",
       "| TCGA-CV-6951-01A |  3280 |  1 | 1973 |  904 |  300 |  111 |  736 | 1844 | 15010 | 1314 | ⋯ | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 19 | 0 | 44 |\n",
       "| TCGA-CN-4728-01A |  1136 |  1 | 1739 |  668 |  347 | 2618 | 5170 | 2296 |  2764 | 1537 | ⋯ | 0 | 3 | 1 | 1 | 5 | 0 | 0 | 10 | 1 | 12 |\n",
       "| TCGA-CV-7090-01A |  1050 |  3 | 1520 |  464 |  406 |  698 | 2617 | 2863 |  2464 | 1940 | ⋯ | 0 | 5 | 0 | 0 | 1 | 0 | 0 | 15 | 0 |  8 |\n",
       "| TCGA-CV-5979-01A |  1416 |  0 | 1383 |  594 |  517 |  160 | 6088 | 5182 |  3640 | 1324 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 |  8 | 0 | 17 |\n",
       "| TCGA-CQ-7069-01A |   728 |  0 | 1603 |  255 |  165 |  200 | 1027 | 1372 |   796 | 1018 | ⋯ | 0 | 0 | 0 | 1 | 0 | 0 | 0 |  6 | 0 | 10 |\n",
       "| TCGA-CN-4733-01A |   727 |  1 | 1151 |  481 |  463 |  934 | 6624 | 3854 |  2812 | 1833 | ⋯ | 0 | 0 | 0 | 0 | 7 | 0 | 0 |  9 | 0 | 10 |\n",
       "| TCGA-CR-7390-01A |  1995 |  1 | 1561 |  730 |  594 |  382 | 1708 | 2618 | 24128 | 2214 | ⋯ | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 15 | 0 | 32 |\n",
       "| TCGA-CV-A45X-01A |  1795 |  1 | 1913 |  977 |  516 |  211 | 1407 | 1556 |  2578 | 1250 | ⋯ | 0 | 5 | 0 | 3 | 0 | 0 | 0 |  9 | 0 | 14 |\n",
       "| TCGA-IQ-A6SH-01A |  1428 |  0 | 2404 |  393 |  334 |  166 | 6937 | 3944 |  7729 | 1394 | ⋯ | 0 | 3 | 0 | 0 | 3 | 1 | 0 |  9 | 0 | 44 |\n",
       "| TCGA-CV-6962-11A | 11809 |  4 | 1623 |  981 |  299 |  281 | 9783 | 1691 |  2135 | 1369 | ⋯ | 0 | 2 | 0 | 0 | 2 | 0 | 0 |  8 | 0 | 41 |\n",
       "| TCGA-CV-6960-11A |  3340 |  0 | 1388 |  608 |  206 |  304 | 6363 | 1242 |  2100 | 1369 | ⋯ | 0 | 1 | 0 | 2 | 1 | 0 | 0 | 12 | 0 | 19 |\n",
       "| TCGA-CV-A464-01A |   929 |  2 | 2332 |  472 |  386 |  331 | 7799 | 3028 |  2494 | 1711 | ⋯ | 0 | 3 | 1 | 2 | 3 | 0 | 1 |  1 | 0 | 46 |\n",
       "| TCGA-C9-A47Z-01A |  1707 |  0 | 1926 |  410 |  210 |  134 | 1264 | 1356 |  3710 | 1671 | ⋯ | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 35 | 0 | 14 |\n",
       "| TCGA-CN-6010-01A |  2218 |  0 | 1574 |  852 |  729 |  550 | 5558 | 2921 |  8749 | 1596 | ⋯ | 0 | 2 | 0 | 0 | 2 | 0 | 0 | 17 | 0 | 54 |\n",
       "| TCGA-WA-A7GZ-11A |  2537 | 41 | 1171 |  557 |  127 |  165 | 4651 |  647 |  3029 |  848 | ⋯ | 0 | 1 | 0 | 0 | 2 | 0 | 0 | 16 | 0 | 38 |\n",
       "| TCGA-CV-7235-01A |   492 |  0 |  976 |  376 |  363 |  488 | 5178 | 2138 | 20007 | 4131 | ⋯ | 0 | 2 | 2 | 1 | 0 | 0 | 0 |  8 | 0 | 60 |\n",
       "| TCGA-CX-7086-01A |  2741 |  0 | 1952 | 1003 | 1103 |  214 | 1809 | 2639 | 13623 | 2530 | ⋯ | 2 | 2 | 0 | 1 | 0 | 1 | 0 | 11 | 0 | 77 |\n",
       "| TCGA-CV-6935-11A |  8492 |  3 | 1578 |  818 |  281 |  419 | 7368 | 1355 |  2276 | 1583 | ⋯ | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 12 | 0 | 19 |\n",
       "| TCGA-P3-A6SW-01A |   770 |  1 | 1569 |  620 |  591 |  462 | 2082 | 1603 | 31675 | 1473 | ⋯ | 0 | 0 | 2 | 1 | 1 | 0 | 0 |  0 | 1 | 22 |\n",
       "| TCGA-HD-A6HZ-01A |   923 |  0 | 1183 |  607 |  344 |  925 | 2482 | 1769 |  3949 |  899 | ⋯ | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 11 | 1 | 40 |\n",
       "\n"
      ],
      "text/plain": [
       "                 TSPAN6 TNMD DPM1 SCYL3 C1orf112 FGR  CFH   FUCA2 GCLC  NFYA ⋯\n",
       "TCGA-BB-4224-01A  2237   2   1606 1063  1208      256   177 2371   2741 2515 ⋯\n",
       "TCGA-H7-7774-01A  2740   0   1691  803   317      330  5472 2316   8370  816 ⋯\n",
       "TCGA-CV-6943-01A  2686   0   1649  917   402     1535 15358 3490   4671 2080 ⋯\n",
       "TCGA-CN-5374-01A  2086   1   2333 1288  1105      639  5565 2065   2902 1777 ⋯\n",
       "TCGA-CQ-6227-01A 10167   9   3021  537   459      362  6963 4883   3140 2448 ⋯\n",
       "TCGA-CV-6959-01A  1154   6   2766  527   747      906 12856 6120   7448 3527 ⋯\n",
       "TCGA-F7-A61V-01A  1978   1   1762  482   331      147   793 2364   2827 1159 ⋯\n",
       "TCGA-CV-7413-01A  1930   1   1668  671   476      477  3669 3366   2324 1459 ⋯\n",
       "TCGA-CV-7247-01A  1066   1   1760  600   874      204  2791 1837   9779 1916 ⋯\n",
       "TCGA-CR-5249-01A  2538   0   1268 1066   950      924  5289 2584   2971 2572 ⋯\n",
       "TCGA-CQ-5331-01A  1465   0   2612 1027   766     1084 14982 5098   7356 4672 ⋯\n",
       "TCGA-BB-8601-01A  1630   1   1227  764   687       42   357 1270  19713 1255 ⋯\n",
       "TCGA-CV-A45W-01A  2215   0   1139  526   464     1024  1911 1741   8343 1061 ⋯\n",
       "TCGA-CQ-7063-01A   724   0   1220  461   235      668  4934 1323   1859 1229 ⋯\n",
       "TCGA-CN-5373-01A   718   0   1162  577   232      475  6444 2164   2870 1650 ⋯\n",
       "TCGA-CV-A45T-01A  2120   3   2252  614   340      700  4178 1998   1845 1197 ⋯\n",
       "TCGA-HD-A4C1-01A  1273   2   1793  646   461      238  4564 1802   2617 1129 ⋯\n",
       "TCGA-CV-7438-11A  4370   3   2064  648   367      444  3991 1808   3503 1599 ⋯\n",
       "TCGA-CV-5444-01A  1011   0   1488  627   366      607  5459 1695   1224 1192 ⋯\n",
       "TCGA-BA-5556-01A  1646   1   2146  763   538      967  9401 2521   3916 2173 ⋯\n",
       "TCGA-P3-A6SX-01A  1421   0   2413  794   986       76   563 2652   1788 1105 ⋯\n",
       "TCGA-CV-7242-11A  9952   9   2403  832   437     1000  6336 1563   4157 1589 ⋯\n",
       "TCGA-DQ-7592-01A  2923   0   2507  794   650      484  9116 3996   4762 3113 ⋯\n",
       "TCGA-CV-6937-01A  1232   2   1212  503   210      286   324 1607    866 1250 ⋯\n",
       "TCGA-QK-A8ZB-01A  2332   0   3280  642   507      491  5042 3292   2676 2995 ⋯\n",
       "TCGA-CV-7432-01A  2032   0   2069  434  1081      105  3398 3988   4089 2119 ⋯\n",
       "TCGA-CV-7089-01A  3005   0   2056  601   504      392  3379 3651   2524 1731 ⋯\n",
       "TCGA-CV-6939-11A  1612  53    729  488    45      155 10545 1223   1011  492 ⋯\n",
       "TCGA-BA-4075-01A  2950   1   5510  355   710      306  2114 2328   2450 2342 ⋯\n",
       "TCGA-T3-A92M-01A  1679   0   2430  624   759      379  2443 2379   1900 1833 ⋯\n",
       "⋮                ⋮      ⋮    ⋮    ⋮     ⋮        ⋮    ⋮     ⋮     ⋮     ⋮    ⋱\n",
       "TCGA-CV-7430-01A  3632   0   2857  362   389      136  606  3344  18448 1312 ⋯\n",
       "TCGA-D6-A74Q-01A  2368   0   3792  765   541      307 1291  4462   2878  985 ⋯\n",
       "TCGA-CV-7255-01A  5443   0   3542  884   979      135 5880  5834   2829 4707 ⋯\n",
       "TCGA-CQ-6223-01A  1406   1   1875  623   453      555 3190  2858   4875 1946 ⋯\n",
       "TCGA-CV-A460-01A  1049   0   2070  895   853      985 3735  1697   7706 2500 ⋯\n",
       "TCGA-CV-7261-01A  2048   2   1007  750   487      493 1735  2226  13697 1659 ⋯\n",
       "TCGA-CN-4736-01A   980  35   2072  613   287     2004 6050  3235  15570 1748 ⋯\n",
       "TCGA-CR-7404-01A  2646  18   2293 1259  1067     1147 6266  3687   8930 3086 ⋯\n",
       "TCGA-UF-A719-01A  5193   0   1751 1275  1325      203  352  3428  27455 2397 ⋯\n",
       "TCGA-CV-7236-01A  2366   0   1862  392   367      429 5933  2311   4241 3022 ⋯\n",
       "TCGA-CV-6951-01A  3280   1   1973  904   300      111  736  1844  15010 1314 ⋯\n",
       "TCGA-CN-4728-01A  1136   1   1739  668   347     2618 5170  2296   2764 1537 ⋯\n",
       "TCGA-CV-7090-01A  1050   3   1520  464   406      698 2617  2863   2464 1940 ⋯\n",
       "TCGA-CV-5979-01A  1416   0   1383  594   517      160 6088  5182   3640 1324 ⋯\n",
       "TCGA-CQ-7069-01A   728   0   1603  255   165      200 1027  1372    796 1018 ⋯\n",
       "TCGA-CN-4733-01A   727   1   1151  481   463      934 6624  3854   2812 1833 ⋯\n",
       "TCGA-CR-7390-01A  1995   1   1561  730   594      382 1708  2618  24128 2214 ⋯\n",
       "TCGA-CV-A45X-01A  1795   1   1913  977   516      211 1407  1556   2578 1250 ⋯\n",
       "TCGA-IQ-A6SH-01A  1428   0   2404  393   334      166 6937  3944   7729 1394 ⋯\n",
       "TCGA-CV-6962-11A 11809   4   1623  981   299      281 9783  1691   2135 1369 ⋯\n",
       "TCGA-CV-6960-11A  3340   0   1388  608   206      304 6363  1242   2100 1369 ⋯\n",
       "TCGA-CV-A464-01A   929   2   2332  472   386      331 7799  3028   2494 1711 ⋯\n",
       "TCGA-C9-A47Z-01A  1707   0   1926  410   210      134 1264  1356   3710 1671 ⋯\n",
       "TCGA-CN-6010-01A  2218   0   1574  852   729      550 5558  2921   8749 1596 ⋯\n",
       "TCGA-WA-A7GZ-11A  2537  41   1171  557   127      165 4651   647   3029  848 ⋯\n",
       "TCGA-CV-7235-01A   492   0    976  376   363      488 5178  2138  20007 4131 ⋯\n",
       "TCGA-CX-7086-01A  2741   0   1952 1003  1103      214 1809  2639  13623 2530 ⋯\n",
       "TCGA-CV-6935-11A  8492   3   1578  818   281      419 7368  1355   2276 1583 ⋯\n",
       "TCGA-P3-A6SW-01A   770   1   1569  620   591      462 2082  1603  31675 1473 ⋯\n",
       "TCGA-HD-A6HZ-01A   923   0   1183  607   344      925 2482  1769   3949  899 ⋯\n",
       "                 LINC00550 LINC01394 LINC00602 MIR1291 LINC00891 PAUPAR\n",
       "TCGA-BB-4224-01A 6         7         0          2      0         6     \n",
       "TCGA-H7-7774-01A 0         1         0          0      2         0     \n",
       "TCGA-CV-6943-01A 0         4         0          2      4         1     \n",
       "TCGA-CN-5374-01A 0         0         1          0      3         0     \n",
       "TCGA-CQ-6227-01A 1         3         0          0      2         0     \n",
       "TCGA-CV-6959-01A 0         1         0          1      3         1     \n",
       "TCGA-F7-A61V-01A 0         0         0          1      1         0     \n",
       "TCGA-CV-7413-01A 0         3         0          0      1         0     \n",
       "TCGA-CV-7247-01A 0         0         0          0      1         0     \n",
       "TCGA-CR-5249-01A 0         0         0          4      6         0     \n",
       "TCGA-CQ-5331-01A 0         1         1          2      1         0     \n",
       "TCGA-BB-8601-01A 1         0         0          3      0         0     \n",
       "TCGA-CV-A45W-01A 1         2         1          3      4         0     \n",
       "TCGA-CQ-7063-01A 0         0         0          1      1         0     \n",
       "TCGA-CN-5373-01A 0         0         0          1      1         0     \n",
       "TCGA-CV-A45T-01A 0         4         0          0      1         0     \n",
       "TCGA-HD-A4C1-01A 0         1         0          2      0         0     \n",
       "TCGA-CV-7438-11A 0         0         0          0      0         0     \n",
       "TCGA-CV-5444-01A 0         6         0          0      1         0     \n",
       "TCGA-BA-5556-01A 0         1         0          1      1         0     \n",
       "TCGA-P3-A6SX-01A 0         0         0          0      0         0     \n",
       "TCGA-CV-7242-11A 0         0         0          6      0         0     \n",
       "TCGA-DQ-7592-01A 0         5         1          0      1         0     \n",
       "TCGA-CV-6937-01A 0         2         0          1      0         0     \n",
       "TCGA-QK-A8ZB-01A 0         9         0         11      3         0     \n",
       "TCGA-CV-7432-01A 0         1         0          1      0         0     \n",
       "TCGA-CV-7089-01A 0         0         0          2      0         0     \n",
       "TCGA-CV-6939-11A 0         3         0          0      3         1     \n",
       "TCGA-BA-4075-01A 0         3         1          1      0         0     \n",
       "TCGA-T3-A92M-01A 0         8         0          3      1         0     \n",
       "⋮                ⋮         ⋮         ⋮         ⋮       ⋮         ⋮     \n",
       "TCGA-CV-7430-01A 0         0         0         3       0         0     \n",
       "TCGA-D6-A74Q-01A 0         3         0         1       6         5     \n",
       "TCGA-CV-7255-01A 0         1         0         0       0         0     \n",
       "TCGA-CQ-6223-01A 0         1         0         1       0         0     \n",
       "TCGA-CV-A460-01A 0         6         0         2       4         0     \n",
       "TCGA-CV-7261-01A 0         0         0         0       1         0     \n",
       "TCGA-CN-4736-01A 0         1         0         1       2         0     \n",
       "TCGA-CR-7404-01A 0         4         0         5       2         0     \n",
       "TCGA-UF-A719-01A 0         2         0         1       1         0     \n",
       "TCGA-CV-7236-01A 0         1         1         0       1         0     \n",
       "TCGA-CV-6951-01A 0         1         0         0       0         0     \n",
       "TCGA-CN-4728-01A 0         3         1         1       5         0     \n",
       "TCGA-CV-7090-01A 0         5         0         0       1         0     \n",
       "TCGA-CV-5979-01A 0         0         0         0       0         0     \n",
       "TCGA-CQ-7069-01A 0         0         0         1       0         0     \n",
       "TCGA-CN-4733-01A 0         0         0         0       7         0     \n",
       "TCGA-CR-7390-01A 0         1         0         1       0         0     \n",
       "TCGA-CV-A45X-01A 0         5         0         3       0         0     \n",
       "TCGA-IQ-A6SH-01A 0         3         0         0       3         1     \n",
       "TCGA-CV-6962-11A 0         2         0         0       2         0     \n",
       "TCGA-CV-6960-11A 0         1         0         2       1         0     \n",
       "TCGA-CV-A464-01A 0         3         1         2       3         0     \n",
       "TCGA-C9-A47Z-01A 0         0         0         4       0         0     \n",
       "TCGA-CN-6010-01A 0         2         0         0       2         0     \n",
       "TCGA-WA-A7GZ-11A 0         1         0         0       2         0     \n",
       "TCGA-CV-7235-01A 0         2         2         1       0         0     \n",
       "TCGA-CX-7086-01A 2         2         0         1       0         1     \n",
       "TCGA-CV-6935-11A 0         1         0         1       0         0     \n",
       "TCGA-P3-A6SW-01A 0         0         2         1       1         0     \n",
       "TCGA-HD-A6HZ-01A 0         1         0         0       1         0     \n",
       "                 GIMAP1-GIMAP5 LINC02246 HERC2P7 LINC01144\n",
       "TCGA-BB-4224-01A 0             16        0       144      \n",
       "TCGA-H7-7774-01A 0              6        0        23      \n",
       "TCGA-CV-6943-01A 0             38        0        18      \n",
       "TCGA-CN-5374-01A 0              4        0        31      \n",
       "TCGA-CQ-6227-01A 0             15        0        24      \n",
       "TCGA-CV-6959-01A 0             19        1        15      \n",
       "TCGA-F7-A61V-01A 0             15        0        20      \n",
       "TCGA-CV-7413-01A 0             19        1        23      \n",
       "TCGA-CV-7247-01A 0             17        1        43      \n",
       "TCGA-CR-5249-01A 0             17        1        27      \n",
       "TCGA-CQ-5331-01A 0             18        1        58      \n",
       "TCGA-BB-8601-01A 0              6        0        40      \n",
       "TCGA-CV-A45W-01A 0              0        0        43      \n",
       "TCGA-CQ-7063-01A 0              6        0        10      \n",
       "TCGA-CN-5373-01A 0             10        0         8      \n",
       "TCGA-CV-A45T-01A 0              3        0        25      \n",
       "TCGA-HD-A4C1-01A 0             14        0         2      \n",
       "TCGA-CV-7438-11A 0              9        0        32      \n",
       "TCGA-CV-5444-01A 0              8        0        36      \n",
       "TCGA-BA-5556-01A 0             24        0        13      \n",
       "TCGA-P3-A6SX-01A 0             17        0        19      \n",
       "TCGA-CV-7242-11A 0              7        0        12      \n",
       "TCGA-DQ-7592-01A 0             23        1        30      \n",
       "TCGA-CV-6937-01A 0              3        0       111      \n",
       "TCGA-QK-A8ZB-01A 0              1        0        24      \n",
       "TCGA-CV-7432-01A 0             13        0         4      \n",
       "TCGA-CV-7089-01A 0             18        0        15      \n",
       "TCGA-CV-6939-11A 0              7        0        68      \n",
       "TCGA-BA-4075-01A 0             20        0        10      \n",
       "TCGA-T3-A92M-01A 0             12        0       113      \n",
       "⋮                ⋮             ⋮         ⋮       ⋮        \n",
       "TCGA-CV-7430-01A 0             35        0        4       \n",
       "TCGA-D6-A74Q-01A 0             18        0       26       \n",
       "TCGA-CV-7255-01A 0             21        0       19       \n",
       "TCGA-CQ-6223-01A 0             17        0       50       \n",
       "TCGA-CV-A460-01A 0             10        0       25       \n",
       "TCGA-CV-7261-01A 0             11        1       21       \n",
       "TCGA-CN-4736-01A 0             12        1       20       \n",
       "TCGA-CR-7404-01A 0              6        0       99       \n",
       "TCGA-UF-A719-01A 0              3        0       81       \n",
       "TCGA-CV-7236-01A 0             32        0       22       \n",
       "TCGA-CV-6951-01A 0             19        0       44       \n",
       "TCGA-CN-4728-01A 0             10        1       12       \n",
       "TCGA-CV-7090-01A 0             15        0        8       \n",
       "TCGA-CV-5979-01A 0              8        0       17       \n",
       "TCGA-CQ-7069-01A 0              6        0       10       \n",
       "TCGA-CN-4733-01A 0              9        0       10       \n",
       "TCGA-CR-7390-01A 0             15        0       32       \n",
       "TCGA-CV-A45X-01A 0              9        0       14       \n",
       "TCGA-IQ-A6SH-01A 0              9        0       44       \n",
       "TCGA-CV-6962-11A 0              8        0       41       \n",
       "TCGA-CV-6960-11A 0             12        0       19       \n",
       "TCGA-CV-A464-01A 1              1        0       46       \n",
       "TCGA-C9-A47Z-01A 0             35        0       14       \n",
       "TCGA-CN-6010-01A 0             17        0       54       \n",
       "TCGA-WA-A7GZ-11A 0             16        0       38       \n",
       "TCGA-CV-7235-01A 0              8        0       60       \n",
       "TCGA-CX-7086-01A 0             11        0       77       \n",
       "TCGA-CV-6935-11A 0             12        0       19       \n",
       "TCGA-P3-A6SW-01A 0              0        1       22       \n",
       "TCGA-HD-A6HZ-01A 0             11        1       40       "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "df_TCGA"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 9,
   "id": "318b6c44",
   "metadata": {},
   "outputs": [],
   "source": [
    "# read in marker genes\n",
    "marker_genes_100DEGs <- scan(\"/home/cke/Puram/markers/top100DEGs_pseudobulk.txt\",character(),sep=',')\n",
    "# marker_genes_100 <- scan(\"/home/cke/Puram/top100markers_de_cor_symbol.txt\",character(),sep=',')\n",
    "# marker_genes_50 <- scan(\"/home/cke/Puram/top50markers_de_cor_symbol.txt\",character(),sep=',')\n",
    "# marker_genes_20 <- scan(\"/home/cke/Puram/top20markers_de_cor_symbol.txt\",character(),sep=',')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 15,
   "id": "c365e72a",
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<table class=\"dataframe\">\n",
       "<caption>A data.frame: 4484 × 876</caption>\n",
       "<thead>\n",
       "\t<tr><th></th><th scope=col>WDR66</th><th scope=col>CST3</th><th scope=col>ACTN2</th><th scope=col>CPEB4</th><th scope=col>TMEM176B</th><th scope=col>COL6A2</th><th scope=col>BAG1</th><th scope=col>PELI1</th><th scope=col>COL3A1</th><th scope=col>SIGLEC17P</th><th scope=col>⋯</th><th scope=col>GLUL</th><th scope=col>LMO7</th><th scope=col>ATCAY</th><th scope=col>MCTP1</th><th scope=col>SERPINB5</th><th scope=col>ADRBK2</th><th scope=col>CD84</th><th scope=col>FAM105A</th><th scope=col>ZEB2</th><th scope=col>HLA-DQA2</th></tr>\n",
       "\t<tr><th></th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>⋯</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th></tr>\n",
       "</thead>\n",
       "<tbody>\n",
       "\t<tr><th scope=row>HN28_P15_D06_S330_comb</th><td> 0.0000000</td><td> 338.23758</td><td>0</td><td>30.3704590</td><td>  0.000000</td><td>  37.35117</td><td> 0.0000000</td><td>  0.000000</td><td>1.133014e+03</td><td>0</td><td>⋯</td><td>  50.4691800</td><td>  0.000000</td><td> 1.9999634</td><td>0</td><td>  0.000000</td><td> 0.35999998</td><td>0.8199962</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN28_P6_G05_S173_comb</th><td> 0.0000000</td><td> 456.30435</td><td>0</td><td>26.7896520</td><td>  0.000000</td><td>  76.78827</td><td> 0.0000000</td><td>  0.000000</td><td>6.960726e+01</td><td>0</td><td>⋯</td><td> 287.2902000</td><td>  0.000000</td><td> 2.7299786</td><td>0</td><td>  0.000000</td><td> 1.23998420</td><td>0.0000000</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P14_D11_S239_comb</th><td> 0.0000000</td><td> 240.87555</td><td>0</td><td> 0.1199980</td><td>  0.000000</td><td>   0.00000</td><td>17.1302050</td><td> 89.783410</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td> 153.9518100</td><td>  0.000000</td><td> 1.1000025</td><td>0</td><td> 77.422220</td><td> 0.08000252</td><td>0.6499968</td><td> 0.0000000</td><td>  0.0000000</td><td>1.070037</td></tr>\n",
       "\t<tr><th scope=row>HN26_P14_H05_S281_comb</th><td> 0.0000000</td><td> 325.28128</td><td>0</td><td> 0.0000000</td><td>  0.000000</td><td>  72.78102</td><td> 0.5100024</td><td>  2.110009</td><td>2.895213e+03</td><td>0</td><td>⋯</td><td>1514.4025000</td><td>  0.000000</td><td> 1.6199994</td><td>0</td><td>  0.000000</td><td> 0.21999861</td><td>0.9899895</td><td> 0.0000000</td><td> 96.3980600</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P25_H09_S189_comb</th><td> 2.1799650</td><td> 176.21533</td><td>0</td><td> 0.0000000</td><td>157.049070</td><td>  39.33119</td><td>76.3382600</td><td>  4.290040</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td> 175.1856000</td><td>  0.000000</td><td> 1.7199792</td><td>0</td><td>394.733400</td><td> 0.00000000</td><td>0.5999981</td><td> 0.0000000</td><td>  0.0000000</td><td>4.249981</td></tr>\n",
       "\t<tr><th scope=row>HN26_P14_H06_S282_comb</th><td> 0.0000000</td><td> 330.83463</td><td>0</td><td> 0.5699973</td><td> 61.398808</td><td>   0.00000</td><td>80.9201400</td><td>  0.000000</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td> 306.4926500</td><td>  0.000000</td><td> 0.7099965</td><td>0</td><td>190.384640</td><td> 0.00000000</td><td>0.7099965</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN25_P25_C04_S316_comb</th><td>70.9707000</td><td>1289.21830</td><td>0</td><td> 0.0000000</td><td>  0.000000</td><td>1140.32680</td><td> 1.6500003</td><td>  0.000000</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td>   0.0000000</td><td>  0.000000</td><td>10.1796340</td><td>0</td><td> 16.039469</td><td> 0.78996360</td><td>6.7499870</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P25_A11_S107_comb</th><td> 0.0000000</td><td>  13.30921</td><td>0</td><td> 2.9600384</td><td>  0.000000</td><td>  56.29959</td><td> 0.9499934</td><td>  0.000000</td><td>6.500485e+02</td><td>0</td><td>⋯</td><td>   5.8499690</td><td>  0.000000</td><td> 4.4099965</td><td>0</td><td>  0.000000</td><td>36.55060600</td><td>1.0800163</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P25_C09_S129_comb</th><td> 0.0000000</td><td> 108.90191</td><td>0</td><td> 0.0000000</td><td>  0.000000</td><td>   0.00000</td><td>52.1907500</td><td> 78.073010</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td> 208.9151600</td><td>  0.000000</td><td> 1.5299800</td><td>0</td><td>127.541970</td><td> 0.17000227</td><td>0.7000015</td><td> 0.1899996</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC26_P24_H05_S377_comb</th><td> 0.0000000</td><td> 236.66823</td><td>0</td><td>26.2102970</td><td>  0.000000</td><td>   0.00000</td><td> 0.0000000</td><td>197.364930</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td>   0.8599691</td><td>  0.000000</td><td> 4.1000470</td><td>0</td><td> 96.693474</td><td> 0.37000075</td><td>2.4899700</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN25_P5_E10_S58_comb</th><td> 0.0000000</td><td>1413.50130</td><td>0</td><td>11.7106060</td><td>  0.000000</td><td>  48.79119</td><td>52.0013660</td><td> 92.930595</td><td>2.056865e+03</td><td>0</td><td>⋯</td><td> 194.9215900</td><td>  0.000000</td><td> 1.6299912</td><td>0</td><td>  1.580038</td><td> 0.00000000</td><td>2.6299593</td><td> 0.0000000</td><td> 67.7692600</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN25_P24_B02_S110_comb</th><td>21.6191800</td><td> 926.94990</td><td>0</td><td> 9.2300170</td><td>  0.000000</td><td>   0.00000</td><td>20.9405750</td><td> 23.740936</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td>   0.0000000</td><td>  0.000000</td><td> 0.5400010</td><td>0</td><td>378.084800</td><td> 0.21000095</td><td>0.0000000</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN25_P25_C01_S313_comb</th><td> 0.0000000</td><td>   0.00000</td><td>0</td><td>34.7100750</td><td>  0.000000</td><td>   0.00000</td><td> 0.0000000</td><td>569.404900</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td>   0.0000000</td><td>  0.000000</td><td> 3.8299890</td><td>0</td><td>  0.000000</td><td> 0.88997010</td><td>0.9499934</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN28_P15_G06_S366_comb</th><td> 0.0000000</td><td> 362.30164</td><td>0</td><td> 0.0000000</td><td>  0.000000</td><td>  87.00775</td><td> 0.9899895</td><td>  0.000000</td><td>1.391376e+03</td><td>0</td><td>⋯</td><td> 455.4325000</td><td>  0.000000</td><td> 1.6399914</td><td>0</td><td>  0.000000</td><td> 0.00000000</td><td>0.9699732</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P6_B06_S18_comb</th><td> 0.0000000</td><td>   0.00000</td><td>0</td><td> 0.0000000</td><td>  0.000000</td><td>  27.09951</td><td> 0.9099917</td><td>  0.000000</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td>   0.0000000</td><td>  0.000000</td><td> 4.4600244</td><td>0</td><td>  0.000000</td><td> 0.73997027</td><td>0.0000000</td><td> 0.0000000</td><td>542.5756000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN25_P5_C05_S29_comb</th><td> 0.0000000</td><td>2177.89550</td><td>0</td><td>22.7092800</td><td> 29.119827</td><td> 185.43271</td><td> 0.0000000</td><td> 64.990090</td><td>1.247517e+04</td><td>0</td><td>⋯</td><td> 142.2003800</td><td>  0.000000</td><td> 1.4199790</td><td>0</td><td>  0.000000</td><td> 0.48000205</td><td>1.8299994</td><td>39.8191380</td><td>  0.8800109</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN28_P6_D09_S141_comb</th><td> 0.0000000</td><td> 550.87213</td><td>0</td><td> 0.0000000</td><td>  0.000000</td><td>   0.00000</td><td> 2.1000247</td><td>  0.000000</td><td>1.450019e+00</td><td>0</td><td>⋯</td><td>1068.3636000</td><td>  0.000000</td><td> 5.9099580</td><td>0</td><td>  0.000000</td><td> 0.00000000</td><td>0.9600167</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P5_H01_S85_comb</th><td> 0.6100025</td><td>  54.54029</td><td>0</td><td> 0.0000000</td><td>  0.000000</td><td>   0.00000</td><td> 0.0000000</td><td> 76.938790</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td> 167.5311100</td><td>  0.000000</td><td> 4.3199854</td><td>0</td><td>192.226470</td><td> 0.26999870</td><td>1.4199790</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P13_D07_S139_comb</th><td> 0.0000000</td><td> 861.05990</td><td>0</td><td> 0.0000000</td><td>  0.000000</td><td> 173.53712</td><td> 0.0000000</td><td>  0.000000</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td>   0.0000000</td><td>  0.000000</td><td> 4.5199850</td><td>0</td><td>  0.000000</td><td> 0.00000000</td><td>1.4799789</td><td> 0.0000000</td><td> 77.5070950</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P5_E06_S54_comb</th><td> 0.0000000</td><td> 226.58717</td><td>0</td><td> 0.4900023</td><td>  0.000000</td><td>   0.00000</td><td>36.4088500</td><td> 91.050180</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td> 542.3459000</td><td> 28.280243</td><td> 1.4500190</td><td>0</td><td> 93.610620</td><td> 0.52999680</td><td>0.2999976</td><td> 0.0000000</td><td>  0.0000000</td><td>2.070036</td></tr>\n",
       "\t<tr><th scope=row>HN26_P26_H05_S377_comb</th><td> 0.0000000</td><td> 147.83005</td><td>0</td><td> 0.5200021</td><td>  5.350014</td><td>  11.68053</td><td>48.7504540</td><td> 77.671020</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td>  98.4907400</td><td>  2.780019</td><td> 1.5999614</td><td>0</td><td>138.779100</td><td> 0.00000000</td><td>0.6900011</td><td> 0.0000000</td><td>  0.0000000</td><td>5.810029</td></tr>\n",
       "\t<tr><th scope=row>HNSCC26_P24_F12_S360_comb</th><td> 0.0000000</td><td> 115.43778</td><td>0</td><td> 0.0000000</td><td>  0.000000</td><td>   0.00000</td><td> 0.5999981</td><td>  0.000000</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td> 195.4762900</td><td>  0.000000</td><td> 1.0599893</td><td>0</td><td>  0.000000</td><td> 0.29000014</td><td>0.8800109</td><td> 0.2900001</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC26_P24_F03_S351_comb</th><td> 0.0000000</td><td> 197.72458</td><td>0</td><td> 0.0000000</td><td>  0.000000</td><td>   0.00000</td><td> 0.0000000</td><td>109.919970</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td> 220.4369200</td><td>  0.000000</td><td> 3.3800175</td><td>0</td><td>384.923130</td><td> 0.75002490</td><td>1.5199943</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P6_D08_S44_comb</th><td> 0.0000000</td><td>  96.76745</td><td>0</td><td>55.1515730</td><td>  0.000000</td><td>   0.00000</td><td>37.7201960</td><td>204.335660</td><td>1.899996e-01</td><td>0</td><td>⋯</td><td>   0.0000000</td><td>117.462420</td><td> 3.4399707</td><td>0</td><td>  0.000000</td><td> 0.11999796</td><td>1.0700366</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN25_P5_E12_S60_comb</th><td> 0.0000000</td><td>1086.37680</td><td>0</td><td>21.8899100</td><td>  0.000000</td><td> 120.21286</td><td> 0.0000000</td><td>  1.330017</td><td>1.082690e+02</td><td>0</td><td>⋯</td><td>  85.3610400</td><td>  0.000000</td><td> 3.9200077</td><td>0</td><td>  0.000000</td><td> 0.00000000</td><td>0.6200017</td><td> 0.0000000</td><td> 67.3982000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC26_P24_C01_S313_comb</th><td> 0.0000000</td><td>  57.51930</td><td>0</td><td> 3.5000055</td><td>  0.000000</td><td>   0.00000</td><td>12.7300370</td><td> 45.558205</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td> 161.6383500</td><td>  0.000000</td><td> 3.8299890</td><td>0</td><td>  2.500017</td><td> 0.00000000</td><td>0.3399987</td><td> 0.2999976</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN25_P5_F01_S61_comb</th><td> 0.0000000</td><td>1163.92790</td><td>0</td><td>27.9710520</td><td>  0.000000</td><td> 143.97241</td><td> 2.3299760</td><td>  0.000000</td><td>4.923079e+02</td><td>0</td><td>⋯</td><td> 232.4138200</td><td>  0.000000</td><td> 5.0499635</td><td>0</td><td>  0.000000</td><td> 0.00000000</td><td>0.0000000</td><td> 0.0000000</td><td> 87.5809800</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P5_D12_S48_comb</th><td> 0.0000000</td><td>1195.92800</td><td>0</td><td>49.6614900</td><td>  0.000000</td><td> 420.72644</td><td> 0.0000000</td><td>  0.000000</td><td>6.908821e+02</td><td>0</td><td>⋯</td><td>   0.0000000</td><td>  0.000000</td><td> 4.1399794</td><td>0</td><td>  0.000000</td><td> 0.00000000</td><td>0.6699987</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN25_P25_C11_S323_comb</th><td> 0.0000000</td><td>4091.76200</td><td>0</td><td>52.7580260</td><td>  0.000000</td><td>  41.57958</td><td> 0.4099995</td><td>  0.000000</td><td>1.287688e+03</td><td>0</td><td>⋯</td><td> 221.4133100</td><td>  0.000000</td><td> 4.2700460</td><td>0</td><td>  0.000000</td><td>76.02762600</td><td>1.9499949</td><td> 0.0000000</td><td>254.8126200</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN25_P25_B12_S312_comb</th><td>38.6183200</td><td> 348.30096</td><td>0</td><td> 0.0000000</td><td>  0.000000</td><td>   0.00000</td><td> 0.0000000</td><td>  6.029951</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td>   0.0000000</td><td>  0.000000</td><td> 0.2400020</td><td>0</td><td>219.623750</td><td> 0.09999795</td><td>0.2400020</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>⋮</th><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋱</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_A08_S104_comb</th><td> 98.22786</td><td> 744.73590</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td>18.6890470</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td>1196.346100</td><td> 9.299989</td><td>0.4400021</td><td> 29.880957</td><td> 926.88495</td><td> 0.2199986</td><td>0.5400010</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_E10_S154_comb</th><td> 84.82714</td><td>1044.26950</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td>80.8004800</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td>5139.898000</td><td>24.359285</td><td>1.8900106</td><td>121.309555</td><td>2180.62700</td><td> 0.1700023</td><td>1.3499819</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_E02_S146_comb</th><td> 24.34024</td><td> 279.78278</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td> 0.0000000</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td>2884.559600</td><td> 0.000000</td><td>0.0000000</td><td>  0.000000</td><td>2420.48440</td><td> 0.0000000</td><td>0.0000000</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_F10_S262_comb</th><td> 63.45191</td><td> 123.65112</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td> 0.0000000</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td>   0.000000</td><td> 0.000000</td><td>2.1900158</td><td>  0.000000</td><td> 113.54802</td><td> 0.4000034</td><td>0.6499968</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_D04_S136_comb</th><td>136.26372</td><td> 878.80804</td><td>0</td><td>23.281029</td><td>0</td><td> 0.000000</td><td> 3.6399655</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td>1967.727700</td><td> 0.000000</td><td>0.7000015</td><td>136.354980</td><td>2629.46200</td><td> 0.0000000</td><td>0.2199986</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_C06_S222_comb</th><td> 35.00858</td><td> 289.77332</td><td>0</td><td>18.950735</td><td>0</td><td> 0.000000</td><td>17.8407880</td><td> 94.309600</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 472.313750</td><td> 0.000000</td><td>2.5400230</td><td>  0.000000</td><td> 417.15863</td><td>48.3082500</td><td>0.0000000</td><td>0.4400021</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_C12_S228_comb</th><td> 34.80936</td><td> 124.84219</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td> 0.0000000</td><td> 55.350580</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 427.769650</td><td> 0.000000</td><td>2.3900328</td><td>  0.000000</td><td> 481.56150</td><td> 0.0000000</td><td>0.0000000</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_H04_S184_comb</th><td> 79.17875</td><td> 228.26581</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td>12.2206340</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 642.090400</td><td>34.539950</td><td>0.1999989</td><td> 13.729801</td><td> 705.46040</td><td> 0.0000000</td><td>0.1299988</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_C06_S126_comb</th><td> 62.65187</td><td> 730.99915</td><td>0</td><td> 8.150005</td><td>0</td><td> 0.000000</td><td>17.4308620</td><td> 39.160515</td><td>0.0000000</td><td>0</td><td>⋯</td><td>5796.399400</td><td>14.730647</td><td>0.0000000</td><td>  2.679958</td><td>2165.04270</td><td> 1.6399914</td><td>0.5600012</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_D01_S37_comb</th><td>252.43713</td><td> 122.98577</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td> 0.0000000</td><td> 42.470260</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 388.580720</td><td>31.910160</td><td>0.5400010</td><td>  0.000000</td><td>  56.91826</td><td> 0.0000000</td><td>0.5699973</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_D09_S45_comb</th><td>214.97612</td><td> 345.67804</td><td>0</td><td> 0.000000</td><td>0</td><td>39.430450</td><td> 0.0000000</td><td> 54.768845</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 279.843050</td><td>14.629716</td><td>1.4999692</td><td>  0.000000</td><td> 116.74879</td><td> 6.1600313</td><td>0.5200021</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_E06_S150_comb</th><td> 47.37014</td><td> 692.34110</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td> 0.3600000</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td>1820.380700</td><td> 5.510014</td><td>0.5900030</td><td> 26.669992</td><td>1429.87520</td><td> 0.0000000</td><td>0.1800031</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_H10_S286_comb</th><td>101.81176</td><td> 280.28537</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td>31.8492000</td><td> 83.320885</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 379.081360</td><td>21.520710</td><td>1.3100084</td><td>  4.640045</td><td> 235.62747</td><td> 9.2300170</td><td>1.2300161</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_A02_S98_comb</th><td> 63.31966</td><td> 321.88235</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td> 0.4900023</td><td> 11.070142</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 623.511960</td><td> 0.000000</td><td>1.5399742</td><td>  0.000000</td><td>1446.63940</td><td> 0.0000000</td><td>0.9099917</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_D01_S229_comb</th><td> 88.10998</td><td> 164.50543</td><td>0</td><td> 0.000000</td><td>0</td><td>12.610611</td><td> 0.6699987</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 183.491730</td><td> 1.430036</td><td>1.2999783</td><td>  0.000000</td><td> 348.69855</td><td> 0.8899701</td><td>0.8199962</td><td>0.7099965</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_G02_S266_comb</th><td>186.69658</td><td> 368.46814</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td>32.1490480</td><td>108.342800</td><td>0.5600012</td><td>0</td><td>⋯</td><td> 216.650910</td><td> 0.000000</td><td>3.8500385</td><td>  0.000000</td><td> 183.86763</td><td> 0.6699987</td><td>0.3700007</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_B04_S112_comb</th><td>259.34810</td><td> 905.76150</td><td>0</td><td>11.480089</td><td>0</td><td> 0.000000</td><td> 1.2399842</td><td>111.316180</td><td>0.0000000</td><td>0</td><td>⋯</td><td>2021.638700</td><td> 0.000000</td><td>1.5199943</td><td>  0.000000</td><td> 288.23962</td><td> 0.3200002</td><td>1.0599893</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_C09_S129_comb</th><td> 33.40015</td><td>1537.18300</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td> 9.3299780</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td>7199.722700</td><td>57.090103</td><td>1.0900049</td><td>  0.000000</td><td>2257.56500</td><td> 0.2699987</td><td>1.5599889</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_A12_S204_comb</th><td> 48.70974</td><td> 222.84532</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td>15.7701330</td><td>100.816440</td><td>0.0000000</td><td>0</td><td>⋯</td><td>   9.459977</td><td> 4.529953</td><td>2.5199604</td><td>  0.000000</td><td> 818.88495</td><td> 0.0000000</td><td>0.4199980</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_F06_S162_comb</th><td>145.57086</td><td> 962.75190</td><td>0</td><td> 1.330017</td><td>0</td><td> 0.000000</td><td>63.9884450</td><td>141.989530</td><td>0.0000000</td><td>0</td><td>⋯</td><td>6650.100000</td><td> 0.000000</td><td>1.4600235</td><td>  0.000000</td><td> 594.13540</td><td> 0.0000000</td><td>0.6499968</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_B10_S22_comb</th><td>186.75113</td><td> 253.65875</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td>15.6791950</td><td> 65.391400</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 810.197800</td><td> 4.499971</td><td>1.2300161</td><td>  0.000000</td><td> 156.13683</td><td> 0.0000000</td><td>1.1100091</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_B11_S215_comb</th><td> 94.36022</td><td> 483.98660</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td>28.8792400</td><td> 98.498260</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 455.142200</td><td>26.840689</td><td>2.4500368</td><td>  0.000000</td><td> 193.43556</td><td> 1.0299786</td><td>0.4199980</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_C08_S32_comb</th><td>350.46817</td><td> 342.97644</td><td>0</td><td> 0.000000</td><td>0</td><td> 7.720017</td><td>54.4508800</td><td>  1.999963</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 156.044720</td><td>36.508680</td><td>2.1799650</td><td>  0.000000</td><td> 524.16000</td><td> 0.0000000</td><td>1.3599777</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_H03_S183_comb</th><td> 93.05196</td><td>1242.96300</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td> 0.0000000</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td>3388.136500</td><td> 3.300035</td><td>0.0000000</td><td>  0.000000</td><td> 452.05734</td><td> 0.1199980</td><td>0.0000000</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_F09_S69_comb</th><td> 60.96954</td><td> 176.91365</td><td>0</td><td> 0.000000</td><td>0</td><td> 7.170000</td><td> 0.0000000</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 225.066990</td><td> 0.000000</td><td>1.5399742</td><td>  0.000000</td><td>  84.84686</td><td> 0.6100025</td><td>0.2799981</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_G12_S180_comb</th><td>127.37999</td><td> 902.90955</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td>10.1698450</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 222.136260</td><td> 0.000000</td><td>2.1599727</td><td>  0.000000</td><td> 689.66870</td><td> 0.4900023</td><td>1.5399742</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_C05_S221_comb</th><td>106.59225</td><td> 794.87897</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td> 0.0000000</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 657.548160</td><td> 0.000000</td><td>5.0300520</td><td>  0.000000</td><td>  85.36765</td><td> 1.0299786</td><td>0.5699973</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_C12_S132_comb</th><td>270.20290</td><td> 605.67630</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td>30.1500000</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td>2413.419000</td><td>36.460350</td><td>0.2199986</td><td>  0.000000</td><td>1068.43850</td><td> 0.1199980</td><td>0.1400024</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_H08_S92_comb</th><td> 32.99891</td><td> 272.60205</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td> 0.0000000</td><td>129.394330</td><td>0.0000000</td><td>0</td><td>⋯</td><td>   0.000000</td><td>13.999428</td><td>2.2700405</td><td>  0.000000</td><td>   0.00000</td><td> 0.5500000</td><td>0.5400010</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_G06_S78_comb</th><td>129.81042</td><td>  81.10941</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td> 0.0000000</td><td>526.534850</td><td>0.0000000</td><td>0</td><td>⋯</td><td>  75.831070</td><td> 4.959998</td><td>0.0000000</td><td>  0.000000</td><td> 195.76134</td><td>17.8890720</td><td>0.3900025</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "A data.frame: 4484 × 876\n",
       "\\begin{tabular}{r|lllllllllllllllllllll}\n",
       "  & WDR66 & CST3 & ACTN2 & CPEB4 & TMEM176B & COL6A2 & BAG1 & PELI1 & COL3A1 & SIGLEC17P & ⋯ & GLUL & LMO7 & ATCAY & MCTP1 & SERPINB5 & ADRBK2 & CD84 & FAM105A & ZEB2 & HLA-DQA2\\\\\n",
       "  & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & ⋯ & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl>\\\\\n",
       "\\hline\n",
       "\tHN28\\_P15\\_D06\\_S330\\_comb &  0.0000000 &  338.23758 & 0 & 30.3704590 &   0.000000 &   37.35117 &  0.0000000 &   0.000000 & 1.133014e+03 & 0 & ⋯ &   50.4691800 &   0.000000 &  1.9999634 & 0 &   0.000000 &  0.35999998 & 0.8199962 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN28\\_P6\\_G05\\_S173\\_comb &  0.0000000 &  456.30435 & 0 & 26.7896520 &   0.000000 &   76.78827 &  0.0000000 &   0.000000 & 6.960726e+01 & 0 & ⋯ &  287.2902000 &   0.000000 &  2.7299786 & 0 &   0.000000 &  1.23998420 & 0.0000000 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN26\\_P14\\_D11\\_S239\\_comb &  0.0000000 &  240.87555 & 0 &  0.1199980 &   0.000000 &    0.00000 & 17.1302050 &  89.783410 & 0.000000e+00 & 0 & ⋯ &  153.9518100 &   0.000000 &  1.1000025 & 0 &  77.422220 &  0.08000252 & 0.6499968 &  0.0000000 &   0.0000000 & 1.070037\\\\\n",
       "\tHN26\\_P14\\_H05\\_S281\\_comb &  0.0000000 &  325.28128 & 0 &  0.0000000 &   0.000000 &   72.78102 &  0.5100024 &   2.110009 & 2.895213e+03 & 0 & ⋯ & 1514.4025000 &   0.000000 &  1.6199994 & 0 &   0.000000 &  0.21999861 & 0.9899895 &  0.0000000 &  96.3980600 & 0.000000\\\\\n",
       "\tHN26\\_P25\\_H09\\_S189\\_comb &  2.1799650 &  176.21533 & 0 &  0.0000000 & 157.049070 &   39.33119 & 76.3382600 &   4.290040 & 0.000000e+00 & 0 & ⋯ &  175.1856000 &   0.000000 &  1.7199792 & 0 & 394.733400 &  0.00000000 & 0.5999981 &  0.0000000 &   0.0000000 & 4.249981\\\\\n",
       "\tHN26\\_P14\\_H06\\_S282\\_comb &  0.0000000 &  330.83463 & 0 &  0.5699973 &  61.398808 &    0.00000 & 80.9201400 &   0.000000 & 0.000000e+00 & 0 & ⋯ &  306.4926500 &   0.000000 &  0.7099965 & 0 & 190.384640 &  0.00000000 & 0.7099965 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN25\\_P25\\_C04\\_S316\\_comb & 70.9707000 & 1289.21830 & 0 &  0.0000000 &   0.000000 & 1140.32680 &  1.6500003 &   0.000000 & 0.000000e+00 & 0 & ⋯ &    0.0000000 &   0.000000 & 10.1796340 & 0 &  16.039469 &  0.78996360 & 6.7499870 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN26\\_P25\\_A11\\_S107\\_comb &  0.0000000 &   13.30921 & 0 &  2.9600384 &   0.000000 &   56.29959 &  0.9499934 &   0.000000 & 6.500485e+02 & 0 & ⋯ &    5.8499690 &   0.000000 &  4.4099965 & 0 &   0.000000 & 36.55060600 & 1.0800163 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN26\\_P25\\_C09\\_S129\\_comb &  0.0000000 &  108.90191 & 0 &  0.0000000 &   0.000000 &    0.00000 & 52.1907500 &  78.073010 & 0.000000e+00 & 0 & ⋯ &  208.9151600 &   0.000000 &  1.5299800 & 0 & 127.541970 &  0.17000227 & 0.7000015 &  0.1899996 &   0.0000000 & 0.000000\\\\\n",
       "\tHNSCC26\\_P24\\_H05\\_S377\\_comb &  0.0000000 &  236.66823 & 0 & 26.2102970 &   0.000000 &    0.00000 &  0.0000000 & 197.364930 & 0.000000e+00 & 0 & ⋯ &    0.8599691 &   0.000000 &  4.1000470 & 0 &  96.693474 &  0.37000075 & 2.4899700 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN25\\_P5\\_E10\\_S58\\_comb &  0.0000000 & 1413.50130 & 0 & 11.7106060 &   0.000000 &   48.79119 & 52.0013660 &  92.930595 & 2.056865e+03 & 0 & ⋯ &  194.9215900 &   0.000000 &  1.6299912 & 0 &   1.580038 &  0.00000000 & 2.6299593 &  0.0000000 &  67.7692600 & 0.000000\\\\\n",
       "\tHN25\\_P24\\_B02\\_S110\\_comb & 21.6191800 &  926.94990 & 0 &  9.2300170 &   0.000000 &    0.00000 & 20.9405750 &  23.740936 & 0.000000e+00 & 0 & ⋯ &    0.0000000 &   0.000000 &  0.5400010 & 0 & 378.084800 &  0.21000095 & 0.0000000 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN25\\_P25\\_C01\\_S313\\_comb &  0.0000000 &    0.00000 & 0 & 34.7100750 &   0.000000 &    0.00000 &  0.0000000 & 569.404900 & 0.000000e+00 & 0 & ⋯ &    0.0000000 &   0.000000 &  3.8299890 & 0 &   0.000000 &  0.88997010 & 0.9499934 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN28\\_P15\\_G06\\_S366\\_comb &  0.0000000 &  362.30164 & 0 &  0.0000000 &   0.000000 &   87.00775 &  0.9899895 &   0.000000 & 1.391376e+03 & 0 & ⋯ &  455.4325000 &   0.000000 &  1.6399914 & 0 &   0.000000 &  0.00000000 & 0.9699732 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN26\\_P6\\_B06\\_S18\\_comb &  0.0000000 &    0.00000 & 0 &  0.0000000 &   0.000000 &   27.09951 &  0.9099917 &   0.000000 & 0.000000e+00 & 0 & ⋯ &    0.0000000 &   0.000000 &  4.4600244 & 0 &   0.000000 &  0.73997027 & 0.0000000 &  0.0000000 & 542.5756000 & 0.000000\\\\\n",
       "\tHN25\\_P5\\_C05\\_S29\\_comb &  0.0000000 & 2177.89550 & 0 & 22.7092800 &  29.119827 &  185.43271 &  0.0000000 &  64.990090 & 1.247517e+04 & 0 & ⋯ &  142.2003800 &   0.000000 &  1.4199790 & 0 &   0.000000 &  0.48000205 & 1.8299994 & 39.8191380 &   0.8800109 & 0.000000\\\\\n",
       "\tHN28\\_P6\\_D09\\_S141\\_comb &  0.0000000 &  550.87213 & 0 &  0.0000000 &   0.000000 &    0.00000 &  2.1000247 &   0.000000 & 1.450019e+00 & 0 & ⋯ & 1068.3636000 &   0.000000 &  5.9099580 & 0 &   0.000000 &  0.00000000 & 0.9600167 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN26\\_P5\\_H01\\_S85\\_comb &  0.6100025 &   54.54029 & 0 &  0.0000000 &   0.000000 &    0.00000 &  0.0000000 &  76.938790 & 0.000000e+00 & 0 & ⋯ &  167.5311100 &   0.000000 &  4.3199854 & 0 & 192.226470 &  0.26999870 & 1.4199790 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN26\\_P13\\_D07\\_S139\\_comb &  0.0000000 &  861.05990 & 0 &  0.0000000 &   0.000000 &  173.53712 &  0.0000000 &   0.000000 & 0.000000e+00 & 0 & ⋯ &    0.0000000 &   0.000000 &  4.5199850 & 0 &   0.000000 &  0.00000000 & 1.4799789 &  0.0000000 &  77.5070950 & 0.000000\\\\\n",
       "\tHN26\\_P5\\_E06\\_S54\\_comb &  0.0000000 &  226.58717 & 0 &  0.4900023 &   0.000000 &    0.00000 & 36.4088500 &  91.050180 & 0.000000e+00 & 0 & ⋯ &  542.3459000 &  28.280243 &  1.4500190 & 0 &  93.610620 &  0.52999680 & 0.2999976 &  0.0000000 &   0.0000000 & 2.070036\\\\\n",
       "\tHN26\\_P26\\_H05\\_S377\\_comb &  0.0000000 &  147.83005 & 0 &  0.5200021 &   5.350014 &   11.68053 & 48.7504540 &  77.671020 & 0.000000e+00 & 0 & ⋯ &   98.4907400 &   2.780019 &  1.5999614 & 0 & 138.779100 &  0.00000000 & 0.6900011 &  0.0000000 &   0.0000000 & 5.810029\\\\\n",
       "\tHNSCC26\\_P24\\_F12\\_S360\\_comb &  0.0000000 &  115.43778 & 0 &  0.0000000 &   0.000000 &    0.00000 &  0.5999981 &   0.000000 & 0.000000e+00 & 0 & ⋯ &  195.4762900 &   0.000000 &  1.0599893 & 0 &   0.000000 &  0.29000014 & 0.8800109 &  0.2900001 &   0.0000000 & 0.000000\\\\\n",
       "\tHNSCC26\\_P24\\_F03\\_S351\\_comb &  0.0000000 &  197.72458 & 0 &  0.0000000 &   0.000000 &    0.00000 &  0.0000000 & 109.919970 & 0.000000e+00 & 0 & ⋯ &  220.4369200 &   0.000000 &  3.3800175 & 0 & 384.923130 &  0.75002490 & 1.5199943 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN26\\_P6\\_D08\\_S44\\_comb &  0.0000000 &   96.76745 & 0 & 55.1515730 &   0.000000 &    0.00000 & 37.7201960 & 204.335660 & 1.899996e-01 & 0 & ⋯ &    0.0000000 & 117.462420 &  3.4399707 & 0 &   0.000000 &  0.11999796 & 1.0700366 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN25\\_P5\\_E12\\_S60\\_comb &  0.0000000 & 1086.37680 & 0 & 21.8899100 &   0.000000 &  120.21286 &  0.0000000 &   1.330017 & 1.082690e+02 & 0 & ⋯ &   85.3610400 &   0.000000 &  3.9200077 & 0 &   0.000000 &  0.00000000 & 0.6200017 &  0.0000000 &  67.3982000 & 0.000000\\\\\n",
       "\tHNSCC26\\_P24\\_C01\\_S313\\_comb &  0.0000000 &   57.51930 & 0 &  3.5000055 &   0.000000 &    0.00000 & 12.7300370 &  45.558205 & 0.000000e+00 & 0 & ⋯ &  161.6383500 &   0.000000 &  3.8299890 & 0 &   2.500017 &  0.00000000 & 0.3399987 &  0.2999976 &   0.0000000 & 0.000000\\\\\n",
       "\tHN25\\_P5\\_F01\\_S61\\_comb &  0.0000000 & 1163.92790 & 0 & 27.9710520 &   0.000000 &  143.97241 &  2.3299760 &   0.000000 & 4.923079e+02 & 0 & ⋯ &  232.4138200 &   0.000000 &  5.0499635 & 0 &   0.000000 &  0.00000000 & 0.0000000 &  0.0000000 &  87.5809800 & 0.000000\\\\\n",
       "\tHN26\\_P5\\_D12\\_S48\\_comb &  0.0000000 & 1195.92800 & 0 & 49.6614900 &   0.000000 &  420.72644 &  0.0000000 &   0.000000 & 6.908821e+02 & 0 & ⋯ &    0.0000000 &   0.000000 &  4.1399794 & 0 &   0.000000 &  0.00000000 & 0.6699987 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN25\\_P25\\_C11\\_S323\\_comb &  0.0000000 & 4091.76200 & 0 & 52.7580260 &   0.000000 &   41.57958 &  0.4099995 &   0.000000 & 1.287688e+03 & 0 & ⋯ &  221.4133100 &   0.000000 &  4.2700460 & 0 &   0.000000 & 76.02762600 & 1.9499949 &  0.0000000 & 254.8126200 & 0.000000\\\\\n",
       "\tHN25\\_P25\\_B12\\_S312\\_comb & 38.6183200 &  348.30096 & 0 &  0.0000000 &   0.000000 &    0.00000 &  0.0000000 &   6.029951 & 0.000000e+00 & 0 & ⋯ &    0.0000000 &   0.000000 &  0.2400020 & 0 & 219.623750 &  0.09999795 & 0.2400020 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\t⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋱ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮\\\\\n",
       "\tHNSCC17\\_P4\\_A08\\_S104\\_comb &  98.22786 &  744.73590 & 0 &  0.000000 & 0 &  0.000000 & 18.6890470 &   0.000000 & 0.0000000 & 0 & ⋯ & 1196.346100 &  9.299989 & 0.4400021 &  29.880957 &  926.88495 &  0.2199986 & 0.5400010 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_E10\\_S154\\_comb &  84.82714 & 1044.26950 & 0 &  0.000000 & 0 &  0.000000 & 80.8004800 &   0.000000 & 0.0000000 & 0 & ⋯ & 5139.898000 & 24.359285 & 1.8900106 & 121.309555 & 2180.62700 &  0.1700023 & 1.3499819 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_E02\\_S146\\_comb &  24.34024 &  279.78278 & 0 &  0.000000 & 0 &  0.000000 &  0.0000000 &   0.000000 & 0.0000000 & 0 & ⋯ & 2884.559600 &  0.000000 & 0.0000000 &   0.000000 & 2420.48440 &  0.0000000 & 0.0000000 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_F10\\_S262\\_comb &  63.45191 &  123.65112 & 0 &  0.000000 & 0 &  0.000000 &  0.0000000 &   0.000000 & 0.0000000 & 0 & ⋯ &    0.000000 &  0.000000 & 2.1900158 &   0.000000 &  113.54802 &  0.4000034 & 0.6499968 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_D04\\_S136\\_comb & 136.26372 &  878.80804 & 0 & 23.281029 & 0 &  0.000000 &  3.6399655 &   0.000000 & 0.0000000 & 0 & ⋯ & 1967.727700 &  0.000000 & 0.7000015 & 136.354980 & 2629.46200 &  0.0000000 & 0.2199986 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_C06\\_S222\\_comb &  35.00858 &  289.77332 & 0 & 18.950735 & 0 &  0.000000 & 17.8407880 &  94.309600 & 0.0000000 & 0 & ⋯ &  472.313750 &  0.000000 & 2.5400230 &   0.000000 &  417.15863 & 48.3082500 & 0.0000000 & 0.4400021 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_C12\\_S228\\_comb &  34.80936 &  124.84219 & 0 &  0.000000 & 0 &  0.000000 &  0.0000000 &  55.350580 & 0.0000000 & 0 & ⋯ &  427.769650 &  0.000000 & 2.3900328 &   0.000000 &  481.56150 &  0.0000000 & 0.0000000 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_H04\\_S184\\_comb &  79.17875 &  228.26581 & 0 &  0.000000 & 0 &  0.000000 & 12.2206340 &   0.000000 & 0.0000000 & 0 & ⋯ &  642.090400 & 34.539950 & 0.1999989 &  13.729801 &  705.46040 &  0.0000000 & 0.1299988 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_C06\\_S126\\_comb &  62.65187 &  730.99915 & 0 &  8.150005 & 0 &  0.000000 & 17.4308620 &  39.160515 & 0.0000000 & 0 & ⋯ & 5796.399400 & 14.730647 & 0.0000000 &   2.679958 & 2165.04270 &  1.6399914 & 0.5600012 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P3\\_D01\\_S37\\_comb & 252.43713 &  122.98577 & 0 &  0.000000 & 0 &  0.000000 &  0.0000000 &  42.470260 & 0.0000000 & 0 & ⋯ &  388.580720 & 31.910160 & 0.5400010 &   0.000000 &   56.91826 &  0.0000000 & 0.5699973 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P3\\_D09\\_S45\\_comb & 214.97612 &  345.67804 & 0 &  0.000000 & 0 & 39.430450 &  0.0000000 &  54.768845 & 0.0000000 & 0 & ⋯ &  279.843050 & 14.629716 & 1.4999692 &   0.000000 &  116.74879 &  6.1600313 & 0.5200021 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_E06\\_S150\\_comb &  47.37014 &  692.34110 & 0 &  0.000000 & 0 &  0.000000 &  0.3600000 &   0.000000 & 0.0000000 & 0 & ⋯ & 1820.380700 &  5.510014 & 0.5900030 &  26.669992 & 1429.87520 &  0.0000000 & 0.1800031 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_H10\\_S286\\_comb & 101.81176 &  280.28537 & 0 &  0.000000 & 0 &  0.000000 & 31.8492000 &  83.320885 & 0.0000000 & 0 & ⋯ &  379.081360 & 21.520710 & 1.3100084 &   4.640045 &  235.62747 &  9.2300170 & 1.2300161 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_A02\\_S98\\_comb &  63.31966 &  321.88235 & 0 &  0.000000 & 0 &  0.000000 &  0.4900023 &  11.070142 & 0.0000000 & 0 & ⋯ &  623.511960 &  0.000000 & 1.5399742 &   0.000000 & 1446.63940 &  0.0000000 & 0.9099917 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_D01\\_S229\\_comb &  88.10998 &  164.50543 & 0 &  0.000000 & 0 & 12.610611 &  0.6699987 &   0.000000 & 0.0000000 & 0 & ⋯ &  183.491730 &  1.430036 & 1.2999783 &   0.000000 &  348.69855 &  0.8899701 & 0.8199962 & 0.7099965 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_G02\\_S266\\_comb & 186.69658 &  368.46814 & 0 &  0.000000 & 0 &  0.000000 & 32.1490480 & 108.342800 & 0.5600012 & 0 & ⋯ &  216.650910 &  0.000000 & 3.8500385 &   0.000000 &  183.86763 &  0.6699987 & 0.3700007 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_B04\\_S112\\_comb & 259.34810 &  905.76150 & 0 & 11.480089 & 0 &  0.000000 &  1.2399842 & 111.316180 & 0.0000000 & 0 & ⋯ & 2021.638700 &  0.000000 & 1.5199943 &   0.000000 &  288.23962 &  0.3200002 & 1.0599893 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_C09\\_S129\\_comb &  33.40015 & 1537.18300 & 0 &  0.000000 & 0 &  0.000000 &  9.3299780 &   0.000000 & 0.0000000 & 0 & ⋯ & 7199.722700 & 57.090103 & 1.0900049 &   0.000000 & 2257.56500 &  0.2699987 & 1.5599889 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_A12\\_S204\\_comb &  48.70974 &  222.84532 & 0 &  0.000000 & 0 &  0.000000 & 15.7701330 & 100.816440 & 0.0000000 & 0 & ⋯ &    9.459977 &  4.529953 & 2.5199604 &   0.000000 &  818.88495 &  0.0000000 & 0.4199980 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_F06\\_S162\\_comb & 145.57086 &  962.75190 & 0 &  1.330017 & 0 &  0.000000 & 63.9884450 & 141.989530 & 0.0000000 & 0 & ⋯ & 6650.100000 &  0.000000 & 1.4600235 &   0.000000 &  594.13540 &  0.0000000 & 0.6499968 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P3\\_B10\\_S22\\_comb & 186.75113 &  253.65875 & 0 &  0.000000 & 0 &  0.000000 & 15.6791950 &  65.391400 & 0.0000000 & 0 & ⋯ &  810.197800 &  4.499971 & 1.2300161 &   0.000000 &  156.13683 &  0.0000000 & 1.1100091 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_B11\\_S215\\_comb &  94.36022 &  483.98660 & 0 &  0.000000 & 0 &  0.000000 & 28.8792400 &  98.498260 & 0.0000000 & 0 & ⋯ &  455.142200 & 26.840689 & 2.4500368 &   0.000000 &  193.43556 &  1.0299786 & 0.4199980 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P3\\_C08\\_S32\\_comb & 350.46817 &  342.97644 & 0 &  0.000000 & 0 &  7.720017 & 54.4508800 &   1.999963 & 0.0000000 & 0 & ⋯ &  156.044720 & 36.508680 & 2.1799650 &   0.000000 &  524.16000 &  0.0000000 & 1.3599777 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_H03\\_S183\\_comb &  93.05196 & 1242.96300 & 0 &  0.000000 & 0 &  0.000000 &  0.0000000 &   0.000000 & 0.0000000 & 0 & ⋯ & 3388.136500 &  3.300035 & 0.0000000 &   0.000000 &  452.05734 &  0.1199980 & 0.0000000 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P3\\_F09\\_S69\\_comb &  60.96954 &  176.91365 & 0 &  0.000000 & 0 &  7.170000 &  0.0000000 &   0.000000 & 0.0000000 & 0 & ⋯ &  225.066990 &  0.000000 & 1.5399742 &   0.000000 &   84.84686 &  0.6100025 & 0.2799981 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_G12\\_S180\\_comb & 127.37999 &  902.90955 & 0 &  0.000000 & 0 &  0.000000 & 10.1698450 &   0.000000 & 0.0000000 & 0 & ⋯ &  222.136260 &  0.000000 & 2.1599727 &   0.000000 &  689.66870 &  0.4900023 & 1.5399742 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_C05\\_S221\\_comb & 106.59225 &  794.87897 & 0 &  0.000000 & 0 &  0.000000 &  0.0000000 &   0.000000 & 0.0000000 & 0 & ⋯ &  657.548160 &  0.000000 & 5.0300520 &   0.000000 &   85.36765 &  1.0299786 & 0.5699973 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_C12\\_S132\\_comb & 270.20290 &  605.67630 & 0 &  0.000000 & 0 &  0.000000 & 30.1500000 &   0.000000 & 0.0000000 & 0 & ⋯ & 2413.419000 & 36.460350 & 0.2199986 &   0.000000 & 1068.43850 &  0.1199980 & 0.1400024 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P3\\_H08\\_S92\\_comb &  32.99891 &  272.60205 & 0 &  0.000000 & 0 &  0.000000 &  0.0000000 & 129.394330 & 0.0000000 & 0 & ⋯ &    0.000000 & 13.999428 & 2.2700405 &   0.000000 &    0.00000 &  0.5500000 & 0.5400010 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P3\\_G06\\_S78\\_comb & 129.81042 &   81.10941 & 0 &  0.000000 & 0 &  0.000000 &  0.0000000 & 526.534850 & 0.0000000 & 0 & ⋯ &   75.831070 &  4.959998 & 0.0000000 &   0.000000 &  195.76134 & 17.8890720 & 0.3900025 & 0.0000000 & 0 & 0\\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "A data.frame: 4484 × 876\n",
       "\n",
       "| <!--/--> | WDR66 &lt;dbl&gt; | CST3 &lt;dbl&gt; | ACTN2 &lt;dbl&gt; | CPEB4 &lt;dbl&gt; | TMEM176B &lt;dbl&gt; | COL6A2 &lt;dbl&gt; | BAG1 &lt;dbl&gt; | PELI1 &lt;dbl&gt; | COL3A1 &lt;dbl&gt; | SIGLEC17P &lt;dbl&gt; | ⋯ ⋯ | GLUL &lt;dbl&gt; | LMO7 &lt;dbl&gt; | ATCAY &lt;dbl&gt; | MCTP1 &lt;dbl&gt; | SERPINB5 &lt;dbl&gt; | ADRBK2 &lt;dbl&gt; | CD84 &lt;dbl&gt; | FAM105A &lt;dbl&gt; | ZEB2 &lt;dbl&gt; | HLA-DQA2 &lt;dbl&gt; |\n",
       "|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|\n",
       "| HN28_P15_D06_S330_comb |  0.0000000 |  338.23758 | 0 | 30.3704590 |   0.000000 |   37.35117 |  0.0000000 |   0.000000 | 1.133014e+03 | 0 | ⋯ |   50.4691800 |   0.000000 |  1.9999634 | 0 |   0.000000 |  0.35999998 | 0.8199962 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN28_P6_G05_S173_comb |  0.0000000 |  456.30435 | 0 | 26.7896520 |   0.000000 |   76.78827 |  0.0000000 |   0.000000 | 6.960726e+01 | 0 | ⋯ |  287.2902000 |   0.000000 |  2.7299786 | 0 |   0.000000 |  1.23998420 | 0.0000000 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN26_P14_D11_S239_comb |  0.0000000 |  240.87555 | 0 |  0.1199980 |   0.000000 |    0.00000 | 17.1302050 |  89.783410 | 0.000000e+00 | 0 | ⋯ |  153.9518100 |   0.000000 |  1.1000025 | 0 |  77.422220 |  0.08000252 | 0.6499968 |  0.0000000 |   0.0000000 | 1.070037 |\n",
       "| HN26_P14_H05_S281_comb |  0.0000000 |  325.28128 | 0 |  0.0000000 |   0.000000 |   72.78102 |  0.5100024 |   2.110009 | 2.895213e+03 | 0 | ⋯ | 1514.4025000 |   0.000000 |  1.6199994 | 0 |   0.000000 |  0.21999861 | 0.9899895 |  0.0000000 |  96.3980600 | 0.000000 |\n",
       "| HN26_P25_H09_S189_comb |  2.1799650 |  176.21533 | 0 |  0.0000000 | 157.049070 |   39.33119 | 76.3382600 |   4.290040 | 0.000000e+00 | 0 | ⋯ |  175.1856000 |   0.000000 |  1.7199792 | 0 | 394.733400 |  0.00000000 | 0.5999981 |  0.0000000 |   0.0000000 | 4.249981 |\n",
       "| HN26_P14_H06_S282_comb |  0.0000000 |  330.83463 | 0 |  0.5699973 |  61.398808 |    0.00000 | 80.9201400 |   0.000000 | 0.000000e+00 | 0 | ⋯ |  306.4926500 |   0.000000 |  0.7099965 | 0 | 190.384640 |  0.00000000 | 0.7099965 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN25_P25_C04_S316_comb | 70.9707000 | 1289.21830 | 0 |  0.0000000 |   0.000000 | 1140.32680 |  1.6500003 |   0.000000 | 0.000000e+00 | 0 | ⋯ |    0.0000000 |   0.000000 | 10.1796340 | 0 |  16.039469 |  0.78996360 | 6.7499870 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN26_P25_A11_S107_comb |  0.0000000 |   13.30921 | 0 |  2.9600384 |   0.000000 |   56.29959 |  0.9499934 |   0.000000 | 6.500485e+02 | 0 | ⋯ |    5.8499690 |   0.000000 |  4.4099965 | 0 |   0.000000 | 36.55060600 | 1.0800163 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN26_P25_C09_S129_comb |  0.0000000 |  108.90191 | 0 |  0.0000000 |   0.000000 |    0.00000 | 52.1907500 |  78.073010 | 0.000000e+00 | 0 | ⋯ |  208.9151600 |   0.000000 |  1.5299800 | 0 | 127.541970 |  0.17000227 | 0.7000015 |  0.1899996 |   0.0000000 | 0.000000 |\n",
       "| HNSCC26_P24_H05_S377_comb |  0.0000000 |  236.66823 | 0 | 26.2102970 |   0.000000 |    0.00000 |  0.0000000 | 197.364930 | 0.000000e+00 | 0 | ⋯ |    0.8599691 |   0.000000 |  4.1000470 | 0 |  96.693474 |  0.37000075 | 2.4899700 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN25_P5_E10_S58_comb |  0.0000000 | 1413.50130 | 0 | 11.7106060 |   0.000000 |   48.79119 | 52.0013660 |  92.930595 | 2.056865e+03 | 0 | ⋯ |  194.9215900 |   0.000000 |  1.6299912 | 0 |   1.580038 |  0.00000000 | 2.6299593 |  0.0000000 |  67.7692600 | 0.000000 |\n",
       "| HN25_P24_B02_S110_comb | 21.6191800 |  926.94990 | 0 |  9.2300170 |   0.000000 |    0.00000 | 20.9405750 |  23.740936 | 0.000000e+00 | 0 | ⋯ |    0.0000000 |   0.000000 |  0.5400010 | 0 | 378.084800 |  0.21000095 | 0.0000000 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN25_P25_C01_S313_comb |  0.0000000 |    0.00000 | 0 | 34.7100750 |   0.000000 |    0.00000 |  0.0000000 | 569.404900 | 0.000000e+00 | 0 | ⋯ |    0.0000000 |   0.000000 |  3.8299890 | 0 |   0.000000 |  0.88997010 | 0.9499934 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN28_P15_G06_S366_comb |  0.0000000 |  362.30164 | 0 |  0.0000000 |   0.000000 |   87.00775 |  0.9899895 |   0.000000 | 1.391376e+03 | 0 | ⋯ |  455.4325000 |   0.000000 |  1.6399914 | 0 |   0.000000 |  0.00000000 | 0.9699732 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN26_P6_B06_S18_comb |  0.0000000 |    0.00000 | 0 |  0.0000000 |   0.000000 |   27.09951 |  0.9099917 |   0.000000 | 0.000000e+00 | 0 | ⋯ |    0.0000000 |   0.000000 |  4.4600244 | 0 |   0.000000 |  0.73997027 | 0.0000000 |  0.0000000 | 542.5756000 | 0.000000 |\n",
       "| HN25_P5_C05_S29_comb |  0.0000000 | 2177.89550 | 0 | 22.7092800 |  29.119827 |  185.43271 |  0.0000000 |  64.990090 | 1.247517e+04 | 0 | ⋯ |  142.2003800 |   0.000000 |  1.4199790 | 0 |   0.000000 |  0.48000205 | 1.8299994 | 39.8191380 |   0.8800109 | 0.000000 |\n",
       "| HN28_P6_D09_S141_comb |  0.0000000 |  550.87213 | 0 |  0.0000000 |   0.000000 |    0.00000 |  2.1000247 |   0.000000 | 1.450019e+00 | 0 | ⋯ | 1068.3636000 |   0.000000 |  5.9099580 | 0 |   0.000000 |  0.00000000 | 0.9600167 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN26_P5_H01_S85_comb |  0.6100025 |   54.54029 | 0 |  0.0000000 |   0.000000 |    0.00000 |  0.0000000 |  76.938790 | 0.000000e+00 | 0 | ⋯ |  167.5311100 |   0.000000 |  4.3199854 | 0 | 192.226470 |  0.26999870 | 1.4199790 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN26_P13_D07_S139_comb |  0.0000000 |  861.05990 | 0 |  0.0000000 |   0.000000 |  173.53712 |  0.0000000 |   0.000000 | 0.000000e+00 | 0 | ⋯ |    0.0000000 |   0.000000 |  4.5199850 | 0 |   0.000000 |  0.00000000 | 1.4799789 |  0.0000000 |  77.5070950 | 0.000000 |\n",
       "| HN26_P5_E06_S54_comb |  0.0000000 |  226.58717 | 0 |  0.4900023 |   0.000000 |    0.00000 | 36.4088500 |  91.050180 | 0.000000e+00 | 0 | ⋯ |  542.3459000 |  28.280243 |  1.4500190 | 0 |  93.610620 |  0.52999680 | 0.2999976 |  0.0000000 |   0.0000000 | 2.070036 |\n",
       "| HN26_P26_H05_S377_comb |  0.0000000 |  147.83005 | 0 |  0.5200021 |   5.350014 |   11.68053 | 48.7504540 |  77.671020 | 0.000000e+00 | 0 | ⋯ |   98.4907400 |   2.780019 |  1.5999614 | 0 | 138.779100 |  0.00000000 | 0.6900011 |  0.0000000 |   0.0000000 | 5.810029 |\n",
       "| HNSCC26_P24_F12_S360_comb |  0.0000000 |  115.43778 | 0 |  0.0000000 |   0.000000 |    0.00000 |  0.5999981 |   0.000000 | 0.000000e+00 | 0 | ⋯ |  195.4762900 |   0.000000 |  1.0599893 | 0 |   0.000000 |  0.29000014 | 0.8800109 |  0.2900001 |   0.0000000 | 0.000000 |\n",
       "| HNSCC26_P24_F03_S351_comb |  0.0000000 |  197.72458 | 0 |  0.0000000 |   0.000000 |    0.00000 |  0.0000000 | 109.919970 | 0.000000e+00 | 0 | ⋯ |  220.4369200 |   0.000000 |  3.3800175 | 0 | 384.923130 |  0.75002490 | 1.5199943 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN26_P6_D08_S44_comb |  0.0000000 |   96.76745 | 0 | 55.1515730 |   0.000000 |    0.00000 | 37.7201960 | 204.335660 | 1.899996e-01 | 0 | ⋯ |    0.0000000 | 117.462420 |  3.4399707 | 0 |   0.000000 |  0.11999796 | 1.0700366 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN25_P5_E12_S60_comb |  0.0000000 | 1086.37680 | 0 | 21.8899100 |   0.000000 |  120.21286 |  0.0000000 |   1.330017 | 1.082690e+02 | 0 | ⋯ |   85.3610400 |   0.000000 |  3.9200077 | 0 |   0.000000 |  0.00000000 | 0.6200017 |  0.0000000 |  67.3982000 | 0.000000 |\n",
       "| HNSCC26_P24_C01_S313_comb |  0.0000000 |   57.51930 | 0 |  3.5000055 |   0.000000 |    0.00000 | 12.7300370 |  45.558205 | 0.000000e+00 | 0 | ⋯ |  161.6383500 |   0.000000 |  3.8299890 | 0 |   2.500017 |  0.00000000 | 0.3399987 |  0.2999976 |   0.0000000 | 0.000000 |\n",
       "| HN25_P5_F01_S61_comb |  0.0000000 | 1163.92790 | 0 | 27.9710520 |   0.000000 |  143.97241 |  2.3299760 |   0.000000 | 4.923079e+02 | 0 | ⋯ |  232.4138200 |   0.000000 |  5.0499635 | 0 |   0.000000 |  0.00000000 | 0.0000000 |  0.0000000 |  87.5809800 | 0.000000 |\n",
       "| HN26_P5_D12_S48_comb |  0.0000000 | 1195.92800 | 0 | 49.6614900 |   0.000000 |  420.72644 |  0.0000000 |   0.000000 | 6.908821e+02 | 0 | ⋯ |    0.0000000 |   0.000000 |  4.1399794 | 0 |   0.000000 |  0.00000000 | 0.6699987 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN25_P25_C11_S323_comb |  0.0000000 | 4091.76200 | 0 | 52.7580260 |   0.000000 |   41.57958 |  0.4099995 |   0.000000 | 1.287688e+03 | 0 | ⋯ |  221.4133100 |   0.000000 |  4.2700460 | 0 |   0.000000 | 76.02762600 | 1.9499949 |  0.0000000 | 254.8126200 | 0.000000 |\n",
       "| HN25_P25_B12_S312_comb | 38.6183200 |  348.30096 | 0 |  0.0000000 |   0.000000 |    0.00000 |  0.0000000 |   6.029951 | 0.000000e+00 | 0 | ⋯ |    0.0000000 |   0.000000 |  0.2400020 | 0 | 219.623750 |  0.09999795 | 0.2400020 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋱ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ |\n",
       "| HNSCC17_P4_A08_S104_comb |  98.22786 |  744.73590 | 0 |  0.000000 | 0 |  0.000000 | 18.6890470 |   0.000000 | 0.0000000 | 0 | ⋯ | 1196.346100 |  9.299989 | 0.4400021 |  29.880957 |  926.88495 |  0.2199986 | 0.5400010 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_E10_S154_comb |  84.82714 | 1044.26950 | 0 |  0.000000 | 0 |  0.000000 | 80.8004800 |   0.000000 | 0.0000000 | 0 | ⋯ | 5139.898000 | 24.359285 | 1.8900106 | 121.309555 | 2180.62700 |  0.1700023 | 1.3499819 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_E02_S146_comb |  24.34024 |  279.78278 | 0 |  0.000000 | 0 |  0.000000 |  0.0000000 |   0.000000 | 0.0000000 | 0 | ⋯ | 2884.559600 |  0.000000 | 0.0000000 |   0.000000 | 2420.48440 |  0.0000000 | 0.0000000 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P13_F10_S262_comb |  63.45191 |  123.65112 | 0 |  0.000000 | 0 |  0.000000 |  0.0000000 |   0.000000 | 0.0000000 | 0 | ⋯ |    0.000000 |  0.000000 | 2.1900158 |   0.000000 |  113.54802 |  0.4000034 | 0.6499968 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_D04_S136_comb | 136.26372 |  878.80804 | 0 | 23.281029 | 0 |  0.000000 |  3.6399655 |   0.000000 | 0.0000000 | 0 | ⋯ | 1967.727700 |  0.000000 | 0.7000015 | 136.354980 | 2629.46200 |  0.0000000 | 0.2199986 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P13_C06_S222_comb |  35.00858 |  289.77332 | 0 | 18.950735 | 0 |  0.000000 | 17.8407880 |  94.309600 | 0.0000000 | 0 | ⋯ |  472.313750 |  0.000000 | 2.5400230 |   0.000000 |  417.15863 | 48.3082500 | 0.0000000 | 0.4400021 | 0 | 0 |\n",
       "| HNSCC20_P13_C12_S228_comb |  34.80936 |  124.84219 | 0 |  0.000000 | 0 |  0.000000 |  0.0000000 |  55.350580 | 0.0000000 | 0 | ⋯ |  427.769650 |  0.000000 | 2.3900328 |   0.000000 |  481.56150 |  0.0000000 | 0.0000000 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_H04_S184_comb |  79.17875 |  228.26581 | 0 |  0.000000 | 0 |  0.000000 | 12.2206340 |   0.000000 | 0.0000000 | 0 | ⋯ |  642.090400 | 34.539950 | 0.1999989 |  13.729801 |  705.46040 |  0.0000000 | 0.1299988 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_C06_S126_comb |  62.65187 |  730.99915 | 0 |  8.150005 | 0 |  0.000000 | 17.4308620 |  39.160515 | 0.0000000 | 0 | ⋯ | 5796.399400 | 14.730647 | 0.0000000 |   2.679958 | 2165.04270 |  1.6399914 | 0.5600012 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P3_D01_S37_comb | 252.43713 |  122.98577 | 0 |  0.000000 | 0 |  0.000000 |  0.0000000 |  42.470260 | 0.0000000 | 0 | ⋯ |  388.580720 | 31.910160 | 0.5400010 |   0.000000 |   56.91826 |  0.0000000 | 0.5699973 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P3_D09_S45_comb | 214.97612 |  345.67804 | 0 |  0.000000 | 0 | 39.430450 |  0.0000000 |  54.768845 | 0.0000000 | 0 | ⋯ |  279.843050 | 14.629716 | 1.4999692 |   0.000000 |  116.74879 |  6.1600313 | 0.5200021 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_E06_S150_comb |  47.37014 |  692.34110 | 0 |  0.000000 | 0 |  0.000000 |  0.3600000 |   0.000000 | 0.0000000 | 0 | ⋯ | 1820.380700 |  5.510014 | 0.5900030 |  26.669992 | 1429.87520 |  0.0000000 | 0.1800031 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P13_H10_S286_comb | 101.81176 |  280.28537 | 0 |  0.000000 | 0 |  0.000000 | 31.8492000 |  83.320885 | 0.0000000 | 0 | ⋯ |  379.081360 | 21.520710 | 1.3100084 |   4.640045 |  235.62747 |  9.2300170 | 1.2300161 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_A02_S98_comb |  63.31966 |  321.88235 | 0 |  0.000000 | 0 |  0.000000 |  0.4900023 |  11.070142 | 0.0000000 | 0 | ⋯ |  623.511960 |  0.000000 | 1.5399742 |   0.000000 | 1446.63940 |  0.0000000 | 0.9099917 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P13_D01_S229_comb |  88.10998 |  164.50543 | 0 |  0.000000 | 0 | 12.610611 |  0.6699987 |   0.000000 | 0.0000000 | 0 | ⋯ |  183.491730 |  1.430036 | 1.2999783 |   0.000000 |  348.69855 |  0.8899701 | 0.8199962 | 0.7099965 | 0 | 0 |\n",
       "| HNSCC20_P13_G02_S266_comb | 186.69658 |  368.46814 | 0 |  0.000000 | 0 |  0.000000 | 32.1490480 | 108.342800 | 0.5600012 | 0 | ⋯ |  216.650910 |  0.000000 | 3.8500385 |   0.000000 |  183.86763 |  0.6699987 | 0.3700007 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_B04_S112_comb | 259.34810 |  905.76150 | 0 | 11.480089 | 0 |  0.000000 |  1.2399842 | 111.316180 | 0.0000000 | 0 | ⋯ | 2021.638700 |  0.000000 | 1.5199943 |   0.000000 |  288.23962 |  0.3200002 | 1.0599893 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_C09_S129_comb |  33.40015 | 1537.18300 | 0 |  0.000000 | 0 |  0.000000 |  9.3299780 |   0.000000 | 0.0000000 | 0 | ⋯ | 7199.722700 | 57.090103 | 1.0900049 |   0.000000 | 2257.56500 |  0.2699987 | 1.5599889 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P13_A12_S204_comb |  48.70974 |  222.84532 | 0 |  0.000000 | 0 |  0.000000 | 15.7701330 | 100.816440 | 0.0000000 | 0 | ⋯ |    9.459977 |  4.529953 | 2.5199604 |   0.000000 |  818.88495 |  0.0000000 | 0.4199980 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_F06_S162_comb | 145.57086 |  962.75190 | 0 |  1.330017 | 0 |  0.000000 | 63.9884450 | 141.989530 | 0.0000000 | 0 | ⋯ | 6650.100000 |  0.000000 | 1.4600235 |   0.000000 |  594.13540 |  0.0000000 | 0.6499968 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P3_B10_S22_comb | 186.75113 |  253.65875 | 0 |  0.000000 | 0 |  0.000000 | 15.6791950 |  65.391400 | 0.0000000 | 0 | ⋯ |  810.197800 |  4.499971 | 1.2300161 |   0.000000 |  156.13683 |  0.0000000 | 1.1100091 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P13_B11_S215_comb |  94.36022 |  483.98660 | 0 |  0.000000 | 0 |  0.000000 | 28.8792400 |  98.498260 | 0.0000000 | 0 | ⋯ |  455.142200 | 26.840689 | 2.4500368 |   0.000000 |  193.43556 |  1.0299786 | 0.4199980 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P3_C08_S32_comb | 350.46817 |  342.97644 | 0 |  0.000000 | 0 |  7.720017 | 54.4508800 |   1.999963 | 0.0000000 | 0 | ⋯ |  156.044720 | 36.508680 | 2.1799650 |   0.000000 |  524.16000 |  0.0000000 | 1.3599777 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_H03_S183_comb |  93.05196 | 1242.96300 | 0 |  0.000000 | 0 |  0.000000 |  0.0000000 |   0.000000 | 0.0000000 | 0 | ⋯ | 3388.136500 |  3.300035 | 0.0000000 |   0.000000 |  452.05734 |  0.1199980 | 0.0000000 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P3_F09_S69_comb |  60.96954 |  176.91365 | 0 |  0.000000 | 0 |  7.170000 |  0.0000000 |   0.000000 | 0.0000000 | 0 | ⋯ |  225.066990 |  0.000000 | 1.5399742 |   0.000000 |   84.84686 |  0.6100025 | 0.2799981 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_G12_S180_comb | 127.37999 |  902.90955 | 0 |  0.000000 | 0 |  0.000000 | 10.1698450 |   0.000000 | 0.0000000 | 0 | ⋯ |  222.136260 |  0.000000 | 2.1599727 |   0.000000 |  689.66870 |  0.4900023 | 1.5399742 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P13_C05_S221_comb | 106.59225 |  794.87897 | 0 |  0.000000 | 0 |  0.000000 |  0.0000000 |   0.000000 | 0.0000000 | 0 | ⋯ |  657.548160 |  0.000000 | 5.0300520 |   0.000000 |   85.36765 |  1.0299786 | 0.5699973 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_C12_S132_comb | 270.20290 |  605.67630 | 0 |  0.000000 | 0 |  0.000000 | 30.1500000 |   0.000000 | 0.0000000 | 0 | ⋯ | 2413.419000 | 36.460350 | 0.2199986 |   0.000000 | 1068.43850 |  0.1199980 | 0.1400024 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P3_H08_S92_comb |  32.99891 |  272.60205 | 0 |  0.000000 | 0 |  0.000000 |  0.0000000 | 129.394330 | 0.0000000 | 0 | ⋯ |    0.000000 | 13.999428 | 2.2700405 |   0.000000 |    0.00000 |  0.5500000 | 0.5400010 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P3_G06_S78_comb | 129.81042 |   81.10941 | 0 |  0.000000 | 0 |  0.000000 |  0.0000000 | 526.534850 | 0.0000000 | 0 | ⋯ |   75.831070 |  4.959998 | 0.0000000 |   0.000000 |  195.76134 | 17.8890720 | 0.3900025 | 0.0000000 | 0 | 0 |\n",
       "\n"
      ],
      "text/plain": [
       "                          WDR66      CST3       ACTN2 CPEB4      TMEM176B  \n",
       "HN28_P15_D06_S330_comb     0.0000000  338.23758 0     30.3704590   0.000000\n",
       "HN28_P6_G05_S173_comb      0.0000000  456.30435 0     26.7896520   0.000000\n",
       "HN26_P14_D11_S239_comb     0.0000000  240.87555 0      0.1199980   0.000000\n",
       "HN26_P14_H05_S281_comb     0.0000000  325.28128 0      0.0000000   0.000000\n",
       "HN26_P25_H09_S189_comb     2.1799650  176.21533 0      0.0000000 157.049070\n",
       "HN26_P14_H06_S282_comb     0.0000000  330.83463 0      0.5699973  61.398808\n",
       "HN25_P25_C04_S316_comb    70.9707000 1289.21830 0      0.0000000   0.000000\n",
       "HN26_P25_A11_S107_comb     0.0000000   13.30921 0      2.9600384   0.000000\n",
       "HN26_P25_C09_S129_comb     0.0000000  108.90191 0      0.0000000   0.000000\n",
       "HNSCC26_P24_H05_S377_comb  0.0000000  236.66823 0     26.2102970   0.000000\n",
       "HN25_P5_E10_S58_comb       0.0000000 1413.50130 0     11.7106060   0.000000\n",
       "HN25_P24_B02_S110_comb    21.6191800  926.94990 0      9.2300170   0.000000\n",
       "HN25_P25_C01_S313_comb     0.0000000    0.00000 0     34.7100750   0.000000\n",
       "HN28_P15_G06_S366_comb     0.0000000  362.30164 0      0.0000000   0.000000\n",
       "HN26_P6_B06_S18_comb       0.0000000    0.00000 0      0.0000000   0.000000\n",
       "HN25_P5_C05_S29_comb       0.0000000 2177.89550 0     22.7092800  29.119827\n",
       "HN28_P6_D09_S141_comb      0.0000000  550.87213 0      0.0000000   0.000000\n",
       "HN26_P5_H01_S85_comb       0.6100025   54.54029 0      0.0000000   0.000000\n",
       "HN26_P13_D07_S139_comb     0.0000000  861.05990 0      0.0000000   0.000000\n",
       "HN26_P5_E06_S54_comb       0.0000000  226.58717 0      0.4900023   0.000000\n",
       "HN26_P26_H05_S377_comb     0.0000000  147.83005 0      0.5200021   5.350014\n",
       "HNSCC26_P24_F12_S360_comb  0.0000000  115.43778 0      0.0000000   0.000000\n",
       "HNSCC26_P24_F03_S351_comb  0.0000000  197.72458 0      0.0000000   0.000000\n",
       "HN26_P6_D08_S44_comb       0.0000000   96.76745 0     55.1515730   0.000000\n",
       "HN25_P5_E12_S60_comb       0.0000000 1086.37680 0     21.8899100   0.000000\n",
       "HNSCC26_P24_C01_S313_comb  0.0000000   57.51930 0      3.5000055   0.000000\n",
       "HN25_P5_F01_S61_comb       0.0000000 1163.92790 0     27.9710520   0.000000\n",
       "HN26_P5_D12_S48_comb       0.0000000 1195.92800 0     49.6614900   0.000000\n",
       "HN25_P25_C11_S323_comb     0.0000000 4091.76200 0     52.7580260   0.000000\n",
       "HN25_P25_B12_S312_comb    38.6183200  348.30096 0      0.0000000   0.000000\n",
       "⋮                         ⋮          ⋮          ⋮     ⋮          ⋮         \n",
       "HNSCC17_P4_A08_S104_comb   98.22786   744.73590 0      0.000000  0         \n",
       "HNSCC17_P4_E10_S154_comb   84.82714  1044.26950 0      0.000000  0         \n",
       "HNSCC17_P4_E02_S146_comb   24.34024   279.78278 0      0.000000  0         \n",
       "HNSCC20_P13_F10_S262_comb  63.45191   123.65112 0      0.000000  0         \n",
       "HNSCC17_P4_D04_S136_comb  136.26372   878.80804 0     23.281029  0         \n",
       "HNSCC20_P13_C06_S222_comb  35.00858   289.77332 0     18.950735  0         \n",
       "HNSCC20_P13_C12_S228_comb  34.80936   124.84219 0      0.000000  0         \n",
       "HNSCC17_P4_H04_S184_comb   79.17875   228.26581 0      0.000000  0         \n",
       "HNSCC17_P4_C06_S126_comb   62.65187   730.99915 0      8.150005  0         \n",
       "HNSCC20_P3_D01_S37_comb   252.43713   122.98577 0      0.000000  0         \n",
       "HNSCC20_P3_D09_S45_comb   214.97612   345.67804 0      0.000000  0         \n",
       "HNSCC17_P4_E06_S150_comb   47.37014   692.34110 0      0.000000  0         \n",
       "HNSCC20_P13_H10_S286_comb 101.81176   280.28537 0      0.000000  0         \n",
       "HNSCC17_P4_A02_S98_comb    63.31966   321.88235 0      0.000000  0         \n",
       "HNSCC20_P13_D01_S229_comb  88.10998   164.50543 0      0.000000  0         \n",
       "HNSCC20_P13_G02_S266_comb 186.69658   368.46814 0      0.000000  0         \n",
       "HNSCC17_P4_B04_S112_comb  259.34810   905.76150 0     11.480089  0         \n",
       "HNSCC17_P4_C09_S129_comb   33.40015  1537.18300 0      0.000000  0         \n",
       "HNSCC20_P13_A12_S204_comb  48.70974   222.84532 0      0.000000  0         \n",
       "HNSCC17_P4_F06_S162_comb  145.57086   962.75190 0      1.330017  0         \n",
       "HNSCC20_P3_B10_S22_comb   186.75113   253.65875 0      0.000000  0         \n",
       "HNSCC20_P13_B11_S215_comb  94.36022   483.98660 0      0.000000  0         \n",
       "HNSCC20_P3_C08_S32_comb   350.46817   342.97644 0      0.000000  0         \n",
       "HNSCC17_P4_H03_S183_comb   93.05196  1242.96300 0      0.000000  0         \n",
       "HNSCC20_P3_F09_S69_comb    60.96954   176.91365 0      0.000000  0         \n",
       "HNSCC17_P4_G12_S180_comb  127.37999   902.90955 0      0.000000  0         \n",
       "HNSCC20_P13_C05_S221_comb 106.59225   794.87897 0      0.000000  0         \n",
       "HNSCC17_P4_C12_S132_comb  270.20290   605.67630 0      0.000000  0         \n",
       "HNSCC20_P3_H08_S92_comb    32.99891   272.60205 0      0.000000  0         \n",
       "HNSCC20_P3_G06_S78_comb   129.81042    81.10941 0      0.000000  0         \n",
       "                          COL6A2     BAG1       PELI1      COL3A1      \n",
       "HN28_P15_D06_S330_comb      37.35117  0.0000000   0.000000 1.133014e+03\n",
       "HN28_P6_G05_S173_comb       76.78827  0.0000000   0.000000 6.960726e+01\n",
       "HN26_P14_D11_S239_comb       0.00000 17.1302050  89.783410 0.000000e+00\n",
       "HN26_P14_H05_S281_comb      72.78102  0.5100024   2.110009 2.895213e+03\n",
       "HN26_P25_H09_S189_comb      39.33119 76.3382600   4.290040 0.000000e+00\n",
       "HN26_P14_H06_S282_comb       0.00000 80.9201400   0.000000 0.000000e+00\n",
       "HN25_P25_C04_S316_comb    1140.32680  1.6500003   0.000000 0.000000e+00\n",
       "HN26_P25_A11_S107_comb      56.29959  0.9499934   0.000000 6.500485e+02\n",
       "HN26_P25_C09_S129_comb       0.00000 52.1907500  78.073010 0.000000e+00\n",
       "HNSCC26_P24_H05_S377_comb    0.00000  0.0000000 197.364930 0.000000e+00\n",
       "HN25_P5_E10_S58_comb        48.79119 52.0013660  92.930595 2.056865e+03\n",
       "HN25_P24_B02_S110_comb       0.00000 20.9405750  23.740936 0.000000e+00\n",
       "HN25_P25_C01_S313_comb       0.00000  0.0000000 569.404900 0.000000e+00\n",
       "HN28_P15_G06_S366_comb      87.00775  0.9899895   0.000000 1.391376e+03\n",
       "HN26_P6_B06_S18_comb        27.09951  0.9099917   0.000000 0.000000e+00\n",
       "HN25_P5_C05_S29_comb       185.43271  0.0000000  64.990090 1.247517e+04\n",
       "HN28_P6_D09_S141_comb        0.00000  2.1000247   0.000000 1.450019e+00\n",
       "HN26_P5_H01_S85_comb         0.00000  0.0000000  76.938790 0.000000e+00\n",
       "HN26_P13_D07_S139_comb     173.53712  0.0000000   0.000000 0.000000e+00\n",
       "HN26_P5_E06_S54_comb         0.00000 36.4088500  91.050180 0.000000e+00\n",
       "HN26_P26_H05_S377_comb      11.68053 48.7504540  77.671020 0.000000e+00\n",
       "HNSCC26_P24_F12_S360_comb    0.00000  0.5999981   0.000000 0.000000e+00\n",
       "HNSCC26_P24_F03_S351_comb    0.00000  0.0000000 109.919970 0.000000e+00\n",
       "HN26_P6_D08_S44_comb         0.00000 37.7201960 204.335660 1.899996e-01\n",
       "HN25_P5_E12_S60_comb       120.21286  0.0000000   1.330017 1.082690e+02\n",
       "HNSCC26_P24_C01_S313_comb    0.00000 12.7300370  45.558205 0.000000e+00\n",
       "HN25_P5_F01_S61_comb       143.97241  2.3299760   0.000000 4.923079e+02\n",
       "HN26_P5_D12_S48_comb       420.72644  0.0000000   0.000000 6.908821e+02\n",
       "HN25_P25_C11_S323_comb      41.57958  0.4099995   0.000000 1.287688e+03\n",
       "HN25_P25_B12_S312_comb       0.00000  0.0000000   6.029951 0.000000e+00\n",
       "⋮                         ⋮          ⋮          ⋮          ⋮           \n",
       "HNSCC17_P4_A08_S104_comb   0.000000  18.6890470   0.000000 0.0000000   \n",
       "HNSCC17_P4_E10_S154_comb   0.000000  80.8004800   0.000000 0.0000000   \n",
       "HNSCC17_P4_E02_S146_comb   0.000000   0.0000000   0.000000 0.0000000   \n",
       "HNSCC20_P13_F10_S262_comb  0.000000   0.0000000   0.000000 0.0000000   \n",
       "HNSCC17_P4_D04_S136_comb   0.000000   3.6399655   0.000000 0.0000000   \n",
       "HNSCC20_P13_C06_S222_comb  0.000000  17.8407880  94.309600 0.0000000   \n",
       "HNSCC20_P13_C12_S228_comb  0.000000   0.0000000  55.350580 0.0000000   \n",
       "HNSCC17_P4_H04_S184_comb   0.000000  12.2206340   0.000000 0.0000000   \n",
       "HNSCC17_P4_C06_S126_comb   0.000000  17.4308620  39.160515 0.0000000   \n",
       "HNSCC20_P3_D01_S37_comb    0.000000   0.0000000  42.470260 0.0000000   \n",
       "HNSCC20_P3_D09_S45_comb   39.430450   0.0000000  54.768845 0.0000000   \n",
       "HNSCC17_P4_E06_S150_comb   0.000000   0.3600000   0.000000 0.0000000   \n",
       "HNSCC20_P13_H10_S286_comb  0.000000  31.8492000  83.320885 0.0000000   \n",
       "HNSCC17_P4_A02_S98_comb    0.000000   0.4900023  11.070142 0.0000000   \n",
       "HNSCC20_P13_D01_S229_comb 12.610611   0.6699987   0.000000 0.0000000   \n",
       "HNSCC20_P13_G02_S266_comb  0.000000  32.1490480 108.342800 0.5600012   \n",
       "HNSCC17_P4_B04_S112_comb   0.000000   1.2399842 111.316180 0.0000000   \n",
       "HNSCC17_P4_C09_S129_comb   0.000000   9.3299780   0.000000 0.0000000   \n",
       "HNSCC20_P13_A12_S204_comb  0.000000  15.7701330 100.816440 0.0000000   \n",
       "HNSCC17_P4_F06_S162_comb   0.000000  63.9884450 141.989530 0.0000000   \n",
       "HNSCC20_P3_B10_S22_comb    0.000000  15.6791950  65.391400 0.0000000   \n",
       "HNSCC20_P13_B11_S215_comb  0.000000  28.8792400  98.498260 0.0000000   \n",
       "HNSCC20_P3_C08_S32_comb    7.720017  54.4508800   1.999963 0.0000000   \n",
       "HNSCC17_P4_H03_S183_comb   0.000000   0.0000000   0.000000 0.0000000   \n",
       "HNSCC20_P3_F09_S69_comb    7.170000   0.0000000   0.000000 0.0000000   \n",
       "HNSCC17_P4_G12_S180_comb   0.000000  10.1698450   0.000000 0.0000000   \n",
       "HNSCC20_P13_C05_S221_comb  0.000000   0.0000000   0.000000 0.0000000   \n",
       "HNSCC17_P4_C12_S132_comb   0.000000  30.1500000   0.000000 0.0000000   \n",
       "HNSCC20_P3_H08_S92_comb    0.000000   0.0000000 129.394330 0.0000000   \n",
       "HNSCC20_P3_G06_S78_comb    0.000000   0.0000000 526.534850 0.0000000   \n",
       "                          SIGLEC17P ⋯ GLUL         LMO7       ATCAY     \n",
       "HN28_P15_D06_S330_comb    0         ⋯   50.4691800   0.000000  1.9999634\n",
       "HN28_P6_G05_S173_comb     0         ⋯  287.2902000   0.000000  2.7299786\n",
       "HN26_P14_D11_S239_comb    0         ⋯  153.9518100   0.000000  1.1000025\n",
       "HN26_P14_H05_S281_comb    0         ⋯ 1514.4025000   0.000000  1.6199994\n",
       "HN26_P25_H09_S189_comb    0         ⋯  175.1856000   0.000000  1.7199792\n",
       "HN26_P14_H06_S282_comb    0         ⋯  306.4926500   0.000000  0.7099965\n",
       "HN25_P25_C04_S316_comb    0         ⋯    0.0000000   0.000000 10.1796340\n",
       "HN26_P25_A11_S107_comb    0         ⋯    5.8499690   0.000000  4.4099965\n",
       "HN26_P25_C09_S129_comb    0         ⋯  208.9151600   0.000000  1.5299800\n",
       "HNSCC26_P24_H05_S377_comb 0         ⋯    0.8599691   0.000000  4.1000470\n",
       "HN25_P5_E10_S58_comb      0         ⋯  194.9215900   0.000000  1.6299912\n",
       "HN25_P24_B02_S110_comb    0         ⋯    0.0000000   0.000000  0.5400010\n",
       "HN25_P25_C01_S313_comb    0         ⋯    0.0000000   0.000000  3.8299890\n",
       "HN28_P15_G06_S366_comb    0         ⋯  455.4325000   0.000000  1.6399914\n",
       "HN26_P6_B06_S18_comb      0         ⋯    0.0000000   0.000000  4.4600244\n",
       "HN25_P5_C05_S29_comb      0         ⋯  142.2003800   0.000000  1.4199790\n",
       "HN28_P6_D09_S141_comb     0         ⋯ 1068.3636000   0.000000  5.9099580\n",
       "HN26_P5_H01_S85_comb      0         ⋯  167.5311100   0.000000  4.3199854\n",
       "HN26_P13_D07_S139_comb    0         ⋯    0.0000000   0.000000  4.5199850\n",
       "HN26_P5_E06_S54_comb      0         ⋯  542.3459000  28.280243  1.4500190\n",
       "HN26_P26_H05_S377_comb    0         ⋯   98.4907400   2.780019  1.5999614\n",
       "HNSCC26_P24_F12_S360_comb 0         ⋯  195.4762900   0.000000  1.0599893\n",
       "HNSCC26_P24_F03_S351_comb 0         ⋯  220.4369200   0.000000  3.3800175\n",
       "HN26_P6_D08_S44_comb      0         ⋯    0.0000000 117.462420  3.4399707\n",
       "HN25_P5_E12_S60_comb      0         ⋯   85.3610400   0.000000  3.9200077\n",
       "HNSCC26_P24_C01_S313_comb 0         ⋯  161.6383500   0.000000  3.8299890\n",
       "HN25_P5_F01_S61_comb      0         ⋯  232.4138200   0.000000  5.0499635\n",
       "HN26_P5_D12_S48_comb      0         ⋯    0.0000000   0.000000  4.1399794\n",
       "HN25_P25_C11_S323_comb    0         ⋯  221.4133100   0.000000  4.2700460\n",
       "HN25_P25_B12_S312_comb    0         ⋯    0.0000000   0.000000  0.2400020\n",
       "⋮                         ⋮         ⋱ ⋮            ⋮          ⋮         \n",
       "HNSCC17_P4_A08_S104_comb  0         ⋯ 1196.346100   9.299989  0.4400021 \n",
       "HNSCC17_P4_E10_S154_comb  0         ⋯ 5139.898000  24.359285  1.8900106 \n",
       "HNSCC17_P4_E02_S146_comb  0         ⋯ 2884.559600   0.000000  0.0000000 \n",
       "HNSCC20_P13_F10_S262_comb 0         ⋯    0.000000   0.000000  2.1900158 \n",
       "HNSCC17_P4_D04_S136_comb  0         ⋯ 1967.727700   0.000000  0.7000015 \n",
       "HNSCC20_P13_C06_S222_comb 0         ⋯  472.313750   0.000000  2.5400230 \n",
       "HNSCC20_P13_C12_S228_comb 0         ⋯  427.769650   0.000000  2.3900328 \n",
       "HNSCC17_P4_H04_S184_comb  0         ⋯  642.090400  34.539950  0.1999989 \n",
       "HNSCC17_P4_C06_S126_comb  0         ⋯ 5796.399400  14.730647  0.0000000 \n",
       "HNSCC20_P3_D01_S37_comb   0         ⋯  388.580720  31.910160  0.5400010 \n",
       "HNSCC20_P3_D09_S45_comb   0         ⋯  279.843050  14.629716  1.4999692 \n",
       "HNSCC17_P4_E06_S150_comb  0         ⋯ 1820.380700   5.510014  0.5900030 \n",
       "HNSCC20_P13_H10_S286_comb 0         ⋯  379.081360  21.520710  1.3100084 \n",
       "HNSCC17_P4_A02_S98_comb   0         ⋯  623.511960   0.000000  1.5399742 \n",
       "HNSCC20_P13_D01_S229_comb 0         ⋯  183.491730   1.430036  1.2999783 \n",
       "HNSCC20_P13_G02_S266_comb 0         ⋯  216.650910   0.000000  3.8500385 \n",
       "HNSCC17_P4_B04_S112_comb  0         ⋯ 2021.638700   0.000000  1.5199943 \n",
       "HNSCC17_P4_C09_S129_comb  0         ⋯ 7199.722700  57.090103  1.0900049 \n",
       "HNSCC20_P13_A12_S204_comb 0         ⋯    9.459977   4.529953  2.5199604 \n",
       "HNSCC17_P4_F06_S162_comb  0         ⋯ 6650.100000   0.000000  1.4600235 \n",
       "HNSCC20_P3_B10_S22_comb   0         ⋯  810.197800   4.499971  1.2300161 \n",
       "HNSCC20_P13_B11_S215_comb 0         ⋯  455.142200  26.840689  2.4500368 \n",
       "HNSCC20_P3_C08_S32_comb   0         ⋯  156.044720  36.508680  2.1799650 \n",
       "HNSCC17_P4_H03_S183_comb  0         ⋯ 3388.136500   3.300035  0.0000000 \n",
       "HNSCC20_P3_F09_S69_comb   0         ⋯  225.066990   0.000000  1.5399742 \n",
       "HNSCC17_P4_G12_S180_comb  0         ⋯  222.136260   0.000000  2.1599727 \n",
       "HNSCC20_P13_C05_S221_comb 0         ⋯  657.548160   0.000000  5.0300520 \n",
       "HNSCC17_P4_C12_S132_comb  0         ⋯ 2413.419000  36.460350  0.2199986 \n",
       "HNSCC20_P3_H08_S92_comb   0         ⋯    0.000000  13.999428  2.2700405 \n",
       "HNSCC20_P3_G06_S78_comb   0         ⋯   75.831070   4.959998  0.0000000 \n",
       "                          MCTP1      SERPINB5   ADRBK2      CD84     \n",
       "HN28_P15_D06_S330_comb    0            0.000000  0.35999998 0.8199962\n",
       "HN28_P6_G05_S173_comb     0            0.000000  1.23998420 0.0000000\n",
       "HN26_P14_D11_S239_comb    0           77.422220  0.08000252 0.6499968\n",
       "HN26_P14_H05_S281_comb    0            0.000000  0.21999861 0.9899895\n",
       "HN26_P25_H09_S189_comb    0          394.733400  0.00000000 0.5999981\n",
       "HN26_P14_H06_S282_comb    0          190.384640  0.00000000 0.7099965\n",
       "HN25_P25_C04_S316_comb    0           16.039469  0.78996360 6.7499870\n",
       "HN26_P25_A11_S107_comb    0            0.000000 36.55060600 1.0800163\n",
       "HN26_P25_C09_S129_comb    0          127.541970  0.17000227 0.7000015\n",
       "HNSCC26_P24_H05_S377_comb 0           96.693474  0.37000075 2.4899700\n",
       "HN25_P5_E10_S58_comb      0            1.580038  0.00000000 2.6299593\n",
       "HN25_P24_B02_S110_comb    0          378.084800  0.21000095 0.0000000\n",
       "HN25_P25_C01_S313_comb    0            0.000000  0.88997010 0.9499934\n",
       "HN28_P15_G06_S366_comb    0            0.000000  0.00000000 0.9699732\n",
       "HN26_P6_B06_S18_comb      0            0.000000  0.73997027 0.0000000\n",
       "HN25_P5_C05_S29_comb      0            0.000000  0.48000205 1.8299994\n",
       "HN28_P6_D09_S141_comb     0            0.000000  0.00000000 0.9600167\n",
       "HN26_P5_H01_S85_comb      0          192.226470  0.26999870 1.4199790\n",
       "HN26_P13_D07_S139_comb    0            0.000000  0.00000000 1.4799789\n",
       "HN26_P5_E06_S54_comb      0           93.610620  0.52999680 0.2999976\n",
       "HN26_P26_H05_S377_comb    0          138.779100  0.00000000 0.6900011\n",
       "HNSCC26_P24_F12_S360_comb 0            0.000000  0.29000014 0.8800109\n",
       "HNSCC26_P24_F03_S351_comb 0          384.923130  0.75002490 1.5199943\n",
       "HN26_P6_D08_S44_comb      0            0.000000  0.11999796 1.0700366\n",
       "HN25_P5_E12_S60_comb      0            0.000000  0.00000000 0.6200017\n",
       "HNSCC26_P24_C01_S313_comb 0            2.500017  0.00000000 0.3399987\n",
       "HN25_P5_F01_S61_comb      0            0.000000  0.00000000 0.0000000\n",
       "HN26_P5_D12_S48_comb      0            0.000000  0.00000000 0.6699987\n",
       "HN25_P25_C11_S323_comb    0            0.000000 76.02762600 1.9499949\n",
       "HN25_P25_B12_S312_comb    0          219.623750  0.09999795 0.2400020\n",
       "⋮                         ⋮          ⋮          ⋮           ⋮        \n",
       "HNSCC17_P4_A08_S104_comb   29.880957  926.88495  0.2199986  0.5400010\n",
       "HNSCC17_P4_E10_S154_comb  121.309555 2180.62700  0.1700023  1.3499819\n",
       "HNSCC17_P4_E02_S146_comb    0.000000 2420.48440  0.0000000  0.0000000\n",
       "HNSCC20_P13_F10_S262_comb   0.000000  113.54802  0.4000034  0.6499968\n",
       "HNSCC17_P4_D04_S136_comb  136.354980 2629.46200  0.0000000  0.2199986\n",
       "HNSCC20_P13_C06_S222_comb   0.000000  417.15863 48.3082500  0.0000000\n",
       "HNSCC20_P13_C12_S228_comb   0.000000  481.56150  0.0000000  0.0000000\n",
       "HNSCC17_P4_H04_S184_comb   13.729801  705.46040  0.0000000  0.1299988\n",
       "HNSCC17_P4_C06_S126_comb    2.679958 2165.04270  1.6399914  0.5600012\n",
       "HNSCC20_P3_D01_S37_comb     0.000000   56.91826  0.0000000  0.5699973\n",
       "HNSCC20_P3_D09_S45_comb     0.000000  116.74879  6.1600313  0.5200021\n",
       "HNSCC17_P4_E06_S150_comb   26.669992 1429.87520  0.0000000  0.1800031\n",
       "HNSCC20_P13_H10_S286_comb   4.640045  235.62747  9.2300170  1.2300161\n",
       "HNSCC17_P4_A02_S98_comb     0.000000 1446.63940  0.0000000  0.9099917\n",
       "HNSCC20_P13_D01_S229_comb   0.000000  348.69855  0.8899701  0.8199962\n",
       "HNSCC20_P13_G02_S266_comb   0.000000  183.86763  0.6699987  0.3700007\n",
       "HNSCC17_P4_B04_S112_comb    0.000000  288.23962  0.3200002  1.0599893\n",
       "HNSCC17_P4_C09_S129_comb    0.000000 2257.56500  0.2699987  1.5599889\n",
       "HNSCC20_P13_A12_S204_comb   0.000000  818.88495  0.0000000  0.4199980\n",
       "HNSCC17_P4_F06_S162_comb    0.000000  594.13540  0.0000000  0.6499968\n",
       "HNSCC20_P3_B10_S22_comb     0.000000  156.13683  0.0000000  1.1100091\n",
       "HNSCC20_P13_B11_S215_comb   0.000000  193.43556  1.0299786  0.4199980\n",
       "HNSCC20_P3_C08_S32_comb     0.000000  524.16000  0.0000000  1.3599777\n",
       "HNSCC17_P4_H03_S183_comb    0.000000  452.05734  0.1199980  0.0000000\n",
       "HNSCC20_P3_F09_S69_comb     0.000000   84.84686  0.6100025  0.2799981\n",
       "HNSCC17_P4_G12_S180_comb    0.000000  689.66870  0.4900023  1.5399742\n",
       "HNSCC20_P13_C05_S221_comb   0.000000   85.36765  1.0299786  0.5699973\n",
       "HNSCC17_P4_C12_S132_comb    0.000000 1068.43850  0.1199980  0.1400024\n",
       "HNSCC20_P3_H08_S92_comb     0.000000    0.00000  0.5500000  0.5400010\n",
       "HNSCC20_P3_G06_S78_comb     0.000000  195.76134 17.8890720  0.3900025\n",
       "                          FAM105A    ZEB2        HLA-DQA2\n",
       "HN28_P15_D06_S330_comb     0.0000000   0.0000000 0.000000\n",
       "HN28_P6_G05_S173_comb      0.0000000   0.0000000 0.000000\n",
       "HN26_P14_D11_S239_comb     0.0000000   0.0000000 1.070037\n",
       "HN26_P14_H05_S281_comb     0.0000000  96.3980600 0.000000\n",
       "HN26_P25_H09_S189_comb     0.0000000   0.0000000 4.249981\n",
       "HN26_P14_H06_S282_comb     0.0000000   0.0000000 0.000000\n",
       "HN25_P25_C04_S316_comb     0.0000000   0.0000000 0.000000\n",
       "HN26_P25_A11_S107_comb     0.0000000   0.0000000 0.000000\n",
       "HN26_P25_C09_S129_comb     0.1899996   0.0000000 0.000000\n",
       "HNSCC26_P24_H05_S377_comb  0.0000000   0.0000000 0.000000\n",
       "HN25_P5_E10_S58_comb       0.0000000  67.7692600 0.000000\n",
       "HN25_P24_B02_S110_comb     0.0000000   0.0000000 0.000000\n",
       "HN25_P25_C01_S313_comb     0.0000000   0.0000000 0.000000\n",
       "HN28_P15_G06_S366_comb     0.0000000   0.0000000 0.000000\n",
       "HN26_P6_B06_S18_comb       0.0000000 542.5756000 0.000000\n",
       "HN25_P5_C05_S29_comb      39.8191380   0.8800109 0.000000\n",
       "HN28_P6_D09_S141_comb      0.0000000   0.0000000 0.000000\n",
       "HN26_P5_H01_S85_comb       0.0000000   0.0000000 0.000000\n",
       "HN26_P13_D07_S139_comb     0.0000000  77.5070950 0.000000\n",
       "HN26_P5_E06_S54_comb       0.0000000   0.0000000 2.070036\n",
       "HN26_P26_H05_S377_comb     0.0000000   0.0000000 5.810029\n",
       "HNSCC26_P24_F12_S360_comb  0.2900001   0.0000000 0.000000\n",
       "HNSCC26_P24_F03_S351_comb  0.0000000   0.0000000 0.000000\n",
       "HN26_P6_D08_S44_comb       0.0000000   0.0000000 0.000000\n",
       "HN25_P5_E12_S60_comb       0.0000000  67.3982000 0.000000\n",
       "HNSCC26_P24_C01_S313_comb  0.2999976   0.0000000 0.000000\n",
       "HN25_P5_F01_S61_comb       0.0000000  87.5809800 0.000000\n",
       "HN26_P5_D12_S48_comb       0.0000000   0.0000000 0.000000\n",
       "HN25_P25_C11_S323_comb     0.0000000 254.8126200 0.000000\n",
       "HN25_P25_B12_S312_comb     0.0000000   0.0000000 0.000000\n",
       "⋮                         ⋮          ⋮           ⋮       \n",
       "HNSCC17_P4_A08_S104_comb  0.0000000  0           0       \n",
       "HNSCC17_P4_E10_S154_comb  0.0000000  0           0       \n",
       "HNSCC17_P4_E02_S146_comb  0.0000000  0           0       \n",
       "HNSCC20_P13_F10_S262_comb 0.0000000  0           0       \n",
       "HNSCC17_P4_D04_S136_comb  0.0000000  0           0       \n",
       "HNSCC20_P13_C06_S222_comb 0.4400021  0           0       \n",
       "HNSCC20_P13_C12_S228_comb 0.0000000  0           0       \n",
       "HNSCC17_P4_H04_S184_comb  0.0000000  0           0       \n",
       "HNSCC17_P4_C06_S126_comb  0.0000000  0           0       \n",
       "HNSCC20_P3_D01_S37_comb   0.0000000  0           0       \n",
       "HNSCC20_P3_D09_S45_comb   0.0000000  0           0       \n",
       "HNSCC17_P4_E06_S150_comb  0.0000000  0           0       \n",
       "HNSCC20_P13_H10_S286_comb 0.0000000  0           0       \n",
       "HNSCC17_P4_A02_S98_comb   0.0000000  0           0       \n",
       "HNSCC20_P13_D01_S229_comb 0.7099965  0           0       \n",
       "HNSCC20_P13_G02_S266_comb 0.0000000  0           0       \n",
       "HNSCC17_P4_B04_S112_comb  0.0000000  0           0       \n",
       "HNSCC17_P4_C09_S129_comb  0.0000000  0           0       \n",
       "HNSCC20_P13_A12_S204_comb 0.0000000  0           0       \n",
       "HNSCC17_P4_F06_S162_comb  0.0000000  0           0       \n",
       "HNSCC20_P3_B10_S22_comb   0.0000000  0           0       \n",
       "HNSCC20_P13_B11_S215_comb 0.0000000  0           0       \n",
       "HNSCC20_P3_C08_S32_comb   0.0000000  0           0       \n",
       "HNSCC17_P4_H03_S183_comb  0.0000000  0           0       \n",
       "HNSCC20_P3_F09_S69_comb   0.0000000  0           0       \n",
       "HNSCC17_P4_G12_S180_comb  0.0000000  0           0       \n",
       "HNSCC20_P13_C05_S221_comb 0.0000000  0           0       \n",
       "HNSCC17_P4_C12_S132_comb  0.0000000  0           0       \n",
       "HNSCC20_P3_H08_S92_comb   0.0000000  0           0       \n",
       "HNSCC20_P3_G06_S78_comb   0.0000000  0           0       "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "df_Puram_filtered <- df_Puram[,marker_genes_100DEGs]\n",
    "df_Puram_filtered"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "id": "2be8764e",
   "metadata": {},
   "outputs": [],
   "source": []
  },
  {
   "cell_type": "code",
   "execution_count": 22,
   "id": "c8698c3e",
   "metadata": {},
   "outputs": [],
   "source": [
    "label <- read.table(\"/home/cke/Puram/scRNAlabels/cellcategory_simple_corrected.csv\",sep=',',header=TRUE,row.names = 1)\n",
    "label_subtype <- read.table(\"/home/cke/Puram/scRNAlabels/cellcategory_subtype.csv\",sep=',',header=TRUE,row.names = 1)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 23,
   "id": "1f559e14",
   "metadata": {},
   "outputs": [],
   "source": [
    "label <- subset(label, row.names(label) %in% row.names(df_Puram))\n",
    "label_subtype <- subset(label_subtype, row.names(label_subtype) %in% row.names(df_Puram))"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 24,
   "id": "59cdd26d",
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<table class=\"dataframe\">\n",
       "<caption>A data.frame: 4484 × 1</caption>\n",
       "<thead>\n",
       "\t<tr><th></th><th scope=col>Cell_type</th></tr>\n",
       "\t<tr><th></th><th scope=col>&lt;chr&gt;</th></tr>\n",
       "</thead>\n",
       "<tbody>\n",
       "\t<tr><th scope=row>HN28_P15_D06_S330_comb</th><td>Fibroblast</td></tr>\n",
       "\t<tr><th scope=row>HN28_P6_G05_S173_comb</th><td>Fibroblast</td></tr>\n",
       "\t<tr><th scope=row>HN26_P14_D11_S239_comb</th><td>tumor     </td></tr>\n",
       "\t<tr><th scope=row>HN26_P14_H05_S281_comb</th><td>Fibroblast</td></tr>\n",
       "\t<tr><th scope=row>HN26_P25_H09_S189_comb</th><td>tumor     </td></tr>\n",
       "\t<tr><th scope=row>HN26_P14_H06_S282_comb</th><td>tumor     </td></tr>\n",
       "\t<tr><th scope=row>HN25_P25_C04_S316_comb</th><td>tumor     </td></tr>\n",
       "\t<tr><th scope=row>HN26_P25_A11_S107_comb</th><td>Fibroblast</td></tr>\n",
       "\t<tr><th scope=row>HN26_P25_C09_S129_comb</th><td>tumor     </td></tr>\n",
       "\t<tr><th scope=row>HNSCC26_P24_H05_S377_comb</th><td>tumor     </td></tr>\n",
       "\t<tr><th scope=row>HN25_P5_E10_S58_comb</th><td>Fibroblast</td></tr>\n",
       "\t<tr><th scope=row>HN25_P24_B02_S110_comb</th><td>tumor     </td></tr>\n",
       "\t<tr><th scope=row>HN25_P25_C01_S313_comb</th><td>T cell    </td></tr>\n",
       "\t<tr><th scope=row>HN28_P15_G06_S366_comb</th><td>Fibroblast</td></tr>\n",
       "\t<tr><th scope=row>HN26_P6_B06_S18_comb</th><td>Fibroblast</td></tr>\n",
       "\t<tr><th scope=row>HN25_P5_C05_S29_comb</th><td>Fibroblast</td></tr>\n",
       "\t<tr><th scope=row>HN28_P6_D09_S141_comb</th><td>Fibroblast</td></tr>\n",
       "\t<tr><th scope=row>HN26_P5_H01_S85_comb</th><td>tumor     </td></tr>\n",
       "\t<tr><th scope=row>HN26_P13_D07_S139_comb</th><td>Fibroblast</td></tr>\n",
       "\t<tr><th scope=row>HN26_P5_E06_S54_comb</th><td>tumor     </td></tr>\n",
       "\t<tr><th scope=row>HN26_P26_H05_S377_comb</th><td>tumor     </td></tr>\n",
       "\t<tr><th scope=row>HNSCC26_P24_F12_S360_comb</th><td>tumor     </td></tr>\n",
       "\t<tr><th scope=row>HNSCC26_P24_F03_S351_comb</th><td>tumor     </td></tr>\n",
       "\t<tr><th scope=row>HN26_P6_D08_S44_comb</th><td>tumor     </td></tr>\n",
       "\t<tr><th scope=row>HN25_P5_E12_S60_comb</th><td>Fibroblast</td></tr>\n",
       "\t<tr><th scope=row>HNSCC26_P24_C01_S313_comb</th><td>tumor     </td></tr>\n",
       "\t<tr><th scope=row>HN25_P5_F01_S61_comb</th><td>Fibroblast</td></tr>\n",
       "\t<tr><th scope=row>HN26_P5_D12_S48_comb</th><td>Fibroblast</td></tr>\n",
       "\t<tr><th scope=row>HN25_P25_C11_S323_comb</th><td>Fibroblast</td></tr>\n",
       "\t<tr><th scope=row>HN25_P25_B12_S312_comb</th><td>tumor     </td></tr>\n",
       "\t<tr><th scope=row>⋮</th><td>⋮</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_A08_S104_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_E10_S154_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_E02_S146_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_F10_S262_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_D04_S136_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_C06_S222_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_C12_S228_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_H04_S184_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_C06_S126_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_D01_S37_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_D09_S45_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_E06_S150_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_H10_S286_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_A02_S98_comb</th><td>T cell</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_D01_S229_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_G02_S266_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_B04_S112_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_C09_S129_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_A12_S204_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_F06_S162_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_B10_S22_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_B11_S215_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_C08_S32_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_H03_S183_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_F09_S69_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_G12_S180_comb</th><td>T cell</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_C05_S221_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_C12_S132_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_H08_S92_comb</th><td>tumor </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_G06_S78_comb</th><td>tumor </td></tr>\n",
       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "A data.frame: 4484 × 1\n",
       "\\begin{tabular}{r|l}\n",
       "  & Cell\\_type\\\\\n",
       "  & <chr>\\\\\n",
       "\\hline\n",
       "\tHN28\\_P15\\_D06\\_S330\\_comb & Fibroblast\\\\\n",
       "\tHN28\\_P6\\_G05\\_S173\\_comb & Fibroblast\\\\\n",
       "\tHN26\\_P14\\_D11\\_S239\\_comb & tumor     \\\\\n",
       "\tHN26\\_P14\\_H05\\_S281\\_comb & Fibroblast\\\\\n",
       "\tHN26\\_P25\\_H09\\_S189\\_comb & tumor     \\\\\n",
       "\tHN26\\_P14\\_H06\\_S282\\_comb & tumor     \\\\\n",
       "\tHN25\\_P25\\_C04\\_S316\\_comb & tumor     \\\\\n",
       "\tHN26\\_P25\\_A11\\_S107\\_comb & Fibroblast\\\\\n",
       "\tHN26\\_P25\\_C09\\_S129\\_comb & tumor     \\\\\n",
       "\tHNSCC26\\_P24\\_H05\\_S377\\_comb & tumor     \\\\\n",
       "\tHN25\\_P5\\_E10\\_S58\\_comb & Fibroblast\\\\\n",
       "\tHN25\\_P24\\_B02\\_S110\\_comb & tumor     \\\\\n",
       "\tHN25\\_P25\\_C01\\_S313\\_comb & T cell    \\\\\n",
       "\tHN28\\_P15\\_G06\\_S366\\_comb & Fibroblast\\\\\n",
       "\tHN26\\_P6\\_B06\\_S18\\_comb & Fibroblast\\\\\n",
       "\tHN25\\_P5\\_C05\\_S29\\_comb & Fibroblast\\\\\n",
       "\tHN28\\_P6\\_D09\\_S141\\_comb & Fibroblast\\\\\n",
       "\tHN26\\_P5\\_H01\\_S85\\_comb & tumor     \\\\\n",
       "\tHN26\\_P13\\_D07\\_S139\\_comb & Fibroblast\\\\\n",
       "\tHN26\\_P5\\_E06\\_S54\\_comb & tumor     \\\\\n",
       "\tHN26\\_P26\\_H05\\_S377\\_comb & tumor     \\\\\n",
       "\tHNSCC26\\_P24\\_F12\\_S360\\_comb & tumor     \\\\\n",
       "\tHNSCC26\\_P24\\_F03\\_S351\\_comb & tumor     \\\\\n",
       "\tHN26\\_P6\\_D08\\_S44\\_comb & tumor     \\\\\n",
       "\tHN25\\_P5\\_E12\\_S60\\_comb & Fibroblast\\\\\n",
       "\tHNSCC26\\_P24\\_C01\\_S313\\_comb & tumor     \\\\\n",
       "\tHN25\\_P5\\_F01\\_S61\\_comb & Fibroblast\\\\\n",
       "\tHN26\\_P5\\_D12\\_S48\\_comb & Fibroblast\\\\\n",
       "\tHN25\\_P25\\_C11\\_S323\\_comb & Fibroblast\\\\\n",
       "\tHN25\\_P25\\_B12\\_S312\\_comb & tumor     \\\\\n",
       "\t⋮ & ⋮\\\\\n",
       "\tHNSCC17\\_P4\\_A08\\_S104\\_comb & tumor \\\\\n",
       "\tHNSCC17\\_P4\\_E10\\_S154\\_comb & tumor \\\\\n",
       "\tHNSCC17\\_P4\\_E02\\_S146\\_comb & tumor \\\\\n",
       "\tHNSCC20\\_P13\\_F10\\_S262\\_comb & tumor \\\\\n",
       "\tHNSCC17\\_P4\\_D04\\_S136\\_comb & tumor \\\\\n",
       "\tHNSCC20\\_P13\\_C06\\_S222\\_comb & tumor \\\\\n",
       "\tHNSCC20\\_P13\\_C12\\_S228\\_comb & tumor \\\\\n",
       "\tHNSCC17\\_P4\\_H04\\_S184\\_comb & tumor \\\\\n",
       "\tHNSCC17\\_P4\\_C06\\_S126\\_comb & tumor \\\\\n",
       "\tHNSCC20\\_P3\\_D01\\_S37\\_comb & tumor \\\\\n",
       "\tHNSCC20\\_P3\\_D09\\_S45\\_comb & tumor \\\\\n",
       "\tHNSCC17\\_P4\\_E06\\_S150\\_comb & tumor \\\\\n",
       "\tHNSCC20\\_P13\\_H10\\_S286\\_comb & tumor \\\\\n",
       "\tHNSCC17\\_P4\\_A02\\_S98\\_comb & T cell\\\\\n",
       "\tHNSCC20\\_P13\\_D01\\_S229\\_comb & tumor \\\\\n",
       "\tHNSCC20\\_P13\\_G02\\_S266\\_comb & tumor \\\\\n",
       "\tHNSCC17\\_P4\\_B04\\_S112\\_comb & tumor \\\\\n",
       "\tHNSCC17\\_P4\\_C09\\_S129\\_comb & tumor \\\\\n",
       "\tHNSCC20\\_P13\\_A12\\_S204\\_comb & tumor \\\\\n",
       "\tHNSCC17\\_P4\\_F06\\_S162\\_comb & tumor \\\\\n",
       "\tHNSCC20\\_P3\\_B10\\_S22\\_comb & tumor \\\\\n",
       "\tHNSCC20\\_P13\\_B11\\_S215\\_comb & tumor \\\\\n",
       "\tHNSCC20\\_P3\\_C08\\_S32\\_comb & tumor \\\\\n",
       "\tHNSCC17\\_P4\\_H03\\_S183\\_comb & tumor \\\\\n",
       "\tHNSCC20\\_P3\\_F09\\_S69\\_comb & tumor \\\\\n",
       "\tHNSCC17\\_P4\\_G12\\_S180\\_comb & T cell\\\\\n",
       "\tHNSCC20\\_P13\\_C05\\_S221\\_comb & tumor \\\\\n",
       "\tHNSCC17\\_P4\\_C12\\_S132\\_comb & tumor \\\\\n",
       "\tHNSCC20\\_P3\\_H08\\_S92\\_comb & tumor \\\\\n",
       "\tHNSCC20\\_P3\\_G06\\_S78\\_comb & tumor \\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "A data.frame: 4484 × 1\n",
       "\n",
       "| <!--/--> | Cell_type &lt;chr&gt; |\n",
       "|---|---|\n",
       "| HN28_P15_D06_S330_comb | Fibroblast |\n",
       "| HN28_P6_G05_S173_comb | Fibroblast |\n",
       "| HN26_P14_D11_S239_comb | tumor      |\n",
       "| HN26_P14_H05_S281_comb | Fibroblast |\n",
       "| HN26_P25_H09_S189_comb | tumor      |\n",
       "| HN26_P14_H06_S282_comb | tumor      |\n",
       "| HN25_P25_C04_S316_comb | tumor      |\n",
       "| HN26_P25_A11_S107_comb | Fibroblast |\n",
       "| HN26_P25_C09_S129_comb | tumor      |\n",
       "| HNSCC26_P24_H05_S377_comb | tumor      |\n",
       "| HN25_P5_E10_S58_comb | Fibroblast |\n",
       "| HN25_P24_B02_S110_comb | tumor      |\n",
       "| HN25_P25_C01_S313_comb | T cell     |\n",
       "| HN28_P15_G06_S366_comb | Fibroblast |\n",
       "| HN26_P6_B06_S18_comb | Fibroblast |\n",
       "| HN25_P5_C05_S29_comb | Fibroblast |\n",
       "| HN28_P6_D09_S141_comb | Fibroblast |\n",
       "| HN26_P5_H01_S85_comb | tumor      |\n",
       "| HN26_P13_D07_S139_comb | Fibroblast |\n",
       "| HN26_P5_E06_S54_comb | tumor      |\n",
       "| HN26_P26_H05_S377_comb | tumor      |\n",
       "| HNSCC26_P24_F12_S360_comb | tumor      |\n",
       "| HNSCC26_P24_F03_S351_comb | tumor      |\n",
       "| HN26_P6_D08_S44_comb | tumor      |\n",
       "| HN25_P5_E12_S60_comb | Fibroblast |\n",
       "| HNSCC26_P24_C01_S313_comb | tumor      |\n",
       "| HN25_P5_F01_S61_comb | Fibroblast |\n",
       "| HN26_P5_D12_S48_comb | Fibroblast |\n",
       "| HN25_P25_C11_S323_comb | Fibroblast |\n",
       "| HN25_P25_B12_S312_comb | tumor      |\n",
       "| ⋮ | ⋮ |\n",
       "| HNSCC17_P4_A08_S104_comb | tumor  |\n",
       "| HNSCC17_P4_E10_S154_comb | tumor  |\n",
       "| HNSCC17_P4_E02_S146_comb | tumor  |\n",
       "| HNSCC20_P13_F10_S262_comb | tumor  |\n",
       "| HNSCC17_P4_D04_S136_comb | tumor  |\n",
       "| HNSCC20_P13_C06_S222_comb | tumor  |\n",
       "| HNSCC20_P13_C12_S228_comb | tumor  |\n",
       "| HNSCC17_P4_H04_S184_comb | tumor  |\n",
       "| HNSCC17_P4_C06_S126_comb | tumor  |\n",
       "| HNSCC20_P3_D01_S37_comb | tumor  |\n",
       "| HNSCC20_P3_D09_S45_comb | tumor  |\n",
       "| HNSCC17_P4_E06_S150_comb | tumor  |\n",
       "| HNSCC20_P13_H10_S286_comb | tumor  |\n",
       "| HNSCC17_P4_A02_S98_comb | T cell |\n",
       "| HNSCC20_P13_D01_S229_comb | tumor  |\n",
       "| HNSCC20_P13_G02_S266_comb | tumor  |\n",
       "| HNSCC17_P4_B04_S112_comb | tumor  |\n",
       "| HNSCC17_P4_C09_S129_comb | tumor  |\n",
       "| HNSCC20_P13_A12_S204_comb | tumor  |\n",
       "| HNSCC17_P4_F06_S162_comb | tumor  |\n",
       "| HNSCC20_P3_B10_S22_comb | tumor  |\n",
       "| HNSCC20_P13_B11_S215_comb | tumor  |\n",
       "| HNSCC20_P3_C08_S32_comb | tumor  |\n",
       "| HNSCC17_P4_H03_S183_comb | tumor  |\n",
       "| HNSCC20_P3_F09_S69_comb | tumor  |\n",
       "| HNSCC17_P4_G12_S180_comb | T cell |\n",
       "| HNSCC20_P13_C05_S221_comb | tumor  |\n",
       "| HNSCC17_P4_C12_S132_comb | tumor  |\n",
       "| HNSCC20_P3_H08_S92_comb | tumor  |\n",
       "| HNSCC20_P3_G06_S78_comb | tumor  |\n",
       "\n"
      ],
      "text/plain": [
       "                          Cell_type \n",
       "HN28_P15_D06_S330_comb    Fibroblast\n",
       "HN28_P6_G05_S173_comb     Fibroblast\n",
       "HN26_P14_D11_S239_comb    tumor     \n",
       "HN26_P14_H05_S281_comb    Fibroblast\n",
       "HN26_P25_H09_S189_comb    tumor     \n",
       "HN26_P14_H06_S282_comb    tumor     \n",
       "HN25_P25_C04_S316_comb    tumor     \n",
       "HN26_P25_A11_S107_comb    Fibroblast\n",
       "HN26_P25_C09_S129_comb    tumor     \n",
       "HNSCC26_P24_H05_S377_comb tumor     \n",
       "HN25_P5_E10_S58_comb      Fibroblast\n",
       "HN25_P24_B02_S110_comb    tumor     \n",
       "HN25_P25_C01_S313_comb    T cell    \n",
       "HN28_P15_G06_S366_comb    Fibroblast\n",
       "HN26_P6_B06_S18_comb      Fibroblast\n",
       "HN25_P5_C05_S29_comb      Fibroblast\n",
       "HN28_P6_D09_S141_comb     Fibroblast\n",
       "HN26_P5_H01_S85_comb      tumor     \n",
       "HN26_P13_D07_S139_comb    Fibroblast\n",
       "HN26_P5_E06_S54_comb      tumor     \n",
       "HN26_P26_H05_S377_comb    tumor     \n",
       "HNSCC26_P24_F12_S360_comb tumor     \n",
       "HNSCC26_P24_F03_S351_comb tumor     \n",
       "HN26_P6_D08_S44_comb      tumor     \n",
       "HN25_P5_E12_S60_comb      Fibroblast\n",
       "HNSCC26_P24_C01_S313_comb tumor     \n",
       "HN25_P5_F01_S61_comb      Fibroblast\n",
       "HN26_P5_D12_S48_comb      Fibroblast\n",
       "HN25_P25_C11_S323_comb    Fibroblast\n",
       "HN25_P25_B12_S312_comb    tumor     \n",
       "⋮                         ⋮         \n",
       "HNSCC17_P4_A08_S104_comb  tumor     \n",
       "HNSCC17_P4_E10_S154_comb  tumor     \n",
       "HNSCC17_P4_E02_S146_comb  tumor     \n",
       "HNSCC20_P13_F10_S262_comb tumor     \n",
       "HNSCC17_P4_D04_S136_comb  tumor     \n",
       "HNSCC20_P13_C06_S222_comb tumor     \n",
       "HNSCC20_P13_C12_S228_comb tumor     \n",
       "HNSCC17_P4_H04_S184_comb  tumor     \n",
       "HNSCC17_P4_C06_S126_comb  tumor     \n",
       "HNSCC20_P3_D01_S37_comb   tumor     \n",
       "HNSCC20_P3_D09_S45_comb   tumor     \n",
       "HNSCC17_P4_E06_S150_comb  tumor     \n",
       "HNSCC20_P13_H10_S286_comb tumor     \n",
       "HNSCC17_P4_A02_S98_comb   T cell    \n",
       "HNSCC20_P13_D01_S229_comb tumor     \n",
       "HNSCC20_P13_G02_S266_comb tumor     \n",
       "HNSCC17_P4_B04_S112_comb  tumor     \n",
       "HNSCC17_P4_C09_S129_comb  tumor     \n",
       "HNSCC20_P13_A12_S204_comb tumor     \n",
       "HNSCC17_P4_F06_S162_comb  tumor     \n",
       "HNSCC20_P3_B10_S22_comb   tumor     \n",
       "HNSCC20_P13_B11_S215_comb tumor     \n",
       "HNSCC20_P3_C08_S32_comb   tumor     \n",
       "HNSCC17_P4_H03_S183_comb  tumor     \n",
       "HNSCC20_P3_F09_S69_comb   tumor     \n",
       "HNSCC17_P4_G12_S180_comb  T cell    \n",
       "HNSCC20_P13_C05_S221_comb tumor     \n",
       "HNSCC17_P4_C12_S132_comb  tumor     \n",
       "HNSCC20_P3_H08_S92_comb   tumor     \n",
       "HNSCC20_P3_G06_S78_comb   tumor     "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "label"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 12,
   "id": "ce7b2b5d",
   "metadata": {},
   "outputs": [],
   "source": [
    "# label$cell_category[label$cell_category == NA] <- \"\""
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 26,
   "id": "57723d8e",
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<style>\n",
       ".list-inline {list-style: none; margin:0; padding: 0}\n",
       ".list-inline>li {display: inline-block}\n",
       ".list-inline>li:not(:last-child)::after {content: \"\\00b7\"; padding: 0 .5ex}\n",
       "</style>\n",
       "<ol class=list-inline><li>'Fibroblast'</li><li>'tumor'</li><li>'T cell'</li><li>'Macrophage'</li><li>'Endothelial'</li><li>'B cell'</li><li>'other'</li><li>'Mast'</li></ol>\n"
      ],
      "text/latex": [
       "\\begin{enumerate*}\n",
       "\\item 'Fibroblast'\n",
       "\\item 'tumor'\n",
       "\\item 'T cell'\n",
       "\\item 'Macrophage'\n",
       "\\item 'Endothelial'\n",
       "\\item 'B cell'\n",
       "\\item 'other'\n",
       "\\item 'Mast'\n",
       "\\end{enumerate*}\n"
      ],
      "text/markdown": [
       "1. 'Fibroblast'\n",
       "2. 'tumor'\n",
       "3. 'T cell'\n",
       "4. 'Macrophage'\n",
       "5. 'Endothelial'\n",
       "6. 'B cell'\n",
       "7. 'other'\n",
       "8. 'Mast'\n",
       "\n",
       "\n"
      ],
      "text/plain": [
       "[1] \"Fibroblast\"  \"tumor\"       \"T cell\"      \"Macrophage\"  \"Endothelial\"\n",
       "[6] \"B cell\"      \"other\"       \"Mast\"       "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "unique(label$Cell_type)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 27,
   "id": "334b7ee9",
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<table class=\"dataframe\">\n",
       "<caption>A data.frame: 4484 × 1</caption>\n",
       "<thead>\n",
       "\t<tr><th></th><th scope=col>Ingest_prediction</th></tr>\n",
       "\t<tr><th></th><th scope=col>&lt;chr&gt;</th></tr>\n",
       "</thead>\n",
       "<tbody>\n",
       "\t<tr><th scope=row>HN28_P15_D06_S330_comb</th><td>Fibroblast </td></tr>\n",
       "\t<tr><th scope=row>HN28_P6_G05_S173_comb</th><td>Fibroblast </td></tr>\n",
       "\t<tr><th scope=row>HN26_P14_D11_S239_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HN26_P14_H05_S281_comb</th><td>Fibroblast </td></tr>\n",
       "\t<tr><th scope=row>HN26_P25_H09_S189_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HN26_P14_H06_S282_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HN25_P25_C04_S316_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HN26_P25_A11_S107_comb</th><td>Fibroblast </td></tr>\n",
       "\t<tr><th scope=row>HN26_P25_C09_S129_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC26_P24_H05_S377_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HN25_P5_E10_S58_comb</th><td>Fibroblast </td></tr>\n",
       "\t<tr><th scope=row>HN25_P24_B02_S110_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HN25_P25_C01_S313_comb</th><td>tconv.cells</td></tr>\n",
       "\t<tr><th scope=row>HN28_P15_G06_S366_comb</th><td>Fibroblast </td></tr>\n",
       "\t<tr><th scope=row>HN26_P6_B06_S18_comb</th><td>Fibroblast </td></tr>\n",
       "\t<tr><th scope=row>HN25_P5_C05_S29_comb</th><td>Fibroblast </td></tr>\n",
       "\t<tr><th scope=row>HN28_P6_D09_S141_comb</th><td>Fibroblast </td></tr>\n",
       "\t<tr><th scope=row>HN26_P5_H01_S85_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HN26_P13_D07_S139_comb</th><td>Fibroblast </td></tr>\n",
       "\t<tr><th scope=row>HN26_P5_E06_S54_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HN26_P26_H05_S377_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC26_P24_F12_S360_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC26_P24_F03_S351_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HN26_P6_D08_S44_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HN25_P5_E12_S60_comb</th><td>Fibroblast </td></tr>\n",
       "\t<tr><th scope=row>HNSCC26_P24_C01_S313_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HN25_P5_F01_S61_comb</th><td>Fibroblast </td></tr>\n",
       "\t<tr><th scope=row>HN26_P5_D12_S48_comb</th><td>Fibroblast </td></tr>\n",
       "\t<tr><th scope=row>HN25_P25_C11_S323_comb</th><td>Fibroblast </td></tr>\n",
       "\t<tr><th scope=row>HN25_P25_B12_S312_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>⋮</th><td>⋮</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_A08_S104_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_E10_S154_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_E02_S146_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_F10_S262_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_D04_S136_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_C06_S222_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_C12_S228_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_H04_S184_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_C06_S126_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_D01_S37_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_D09_S45_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_E06_S150_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_H10_S286_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_A02_S98_comb</th><td>tconv.cells</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_D01_S229_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_G02_S266_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_B04_S112_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_C09_S129_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_A12_S204_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_F06_S162_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_B10_S22_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_B11_S215_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_C08_S32_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_H03_S183_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_F09_S69_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_G12_S180_comb</th><td>tconv.cells</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_C05_S221_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_C12_S132_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_H08_S92_comb</th><td>tumor      </td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_G06_S78_comb</th><td>tumor      </td></tr>\n",
       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "A data.frame: 4484 × 1\n",
       "\\begin{tabular}{r|l}\n",
       "  & Ingest\\_prediction\\\\\n",
       "  & <chr>\\\\\n",
       "\\hline\n",
       "\tHN28\\_P15\\_D06\\_S330\\_comb & Fibroblast \\\\\n",
       "\tHN28\\_P6\\_G05\\_S173\\_comb & Fibroblast \\\\\n",
       "\tHN26\\_P14\\_D11\\_S239\\_comb & tumor      \\\\\n",
       "\tHN26\\_P14\\_H05\\_S281\\_comb & Fibroblast \\\\\n",
       "\tHN26\\_P25\\_H09\\_S189\\_comb & tumor      \\\\\n",
       "\tHN26\\_P14\\_H06\\_S282\\_comb & tumor      \\\\\n",
       "\tHN25\\_P25\\_C04\\_S316\\_comb & tumor      \\\\\n",
       "\tHN26\\_P25\\_A11\\_S107\\_comb & Fibroblast \\\\\n",
       "\tHN26\\_P25\\_C09\\_S129\\_comb & tumor      \\\\\n",
       "\tHNSCC26\\_P24\\_H05\\_S377\\_comb & tumor      \\\\\n",
       "\tHN25\\_P5\\_E10\\_S58\\_comb & Fibroblast \\\\\n",
       "\tHN25\\_P24\\_B02\\_S110\\_comb & tumor      \\\\\n",
       "\tHN25\\_P25\\_C01\\_S313\\_comb & tconv.cells\\\\\n",
       "\tHN28\\_P15\\_G06\\_S366\\_comb & Fibroblast \\\\\n",
       "\tHN26\\_P6\\_B06\\_S18\\_comb & Fibroblast \\\\\n",
       "\tHN25\\_P5\\_C05\\_S29\\_comb & Fibroblast \\\\\n",
       "\tHN28\\_P6\\_D09\\_S141\\_comb & Fibroblast \\\\\n",
       "\tHN26\\_P5\\_H01\\_S85\\_comb & tumor      \\\\\n",
       "\tHN26\\_P13\\_D07\\_S139\\_comb & Fibroblast \\\\\n",
       "\tHN26\\_P5\\_E06\\_S54\\_comb & tumor      \\\\\n",
       "\tHN26\\_P26\\_H05\\_S377\\_comb & tumor      \\\\\n",
       "\tHNSCC26\\_P24\\_F12\\_S360\\_comb & tumor      \\\\\n",
       "\tHNSCC26\\_P24\\_F03\\_S351\\_comb & tumor      \\\\\n",
       "\tHN26\\_P6\\_D08\\_S44\\_comb & tumor      \\\\\n",
       "\tHN25\\_P5\\_E12\\_S60\\_comb & Fibroblast \\\\\n",
       "\tHNSCC26\\_P24\\_C01\\_S313\\_comb & tumor      \\\\\n",
       "\tHN25\\_P5\\_F01\\_S61\\_comb & Fibroblast \\\\\n",
       "\tHN26\\_P5\\_D12\\_S48\\_comb & Fibroblast \\\\\n",
       "\tHN25\\_P25\\_C11\\_S323\\_comb & Fibroblast \\\\\n",
       "\tHN25\\_P25\\_B12\\_S312\\_comb & tumor      \\\\\n",
       "\t⋮ & ⋮\\\\\n",
       "\tHNSCC17\\_P4\\_A08\\_S104\\_comb & tumor      \\\\\n",
       "\tHNSCC17\\_P4\\_E10\\_S154\\_comb & tumor      \\\\\n",
       "\tHNSCC17\\_P4\\_E02\\_S146\\_comb & tumor      \\\\\n",
       "\tHNSCC20\\_P13\\_F10\\_S262\\_comb & tumor      \\\\\n",
       "\tHNSCC17\\_P4\\_D04\\_S136\\_comb & tumor      \\\\\n",
       "\tHNSCC20\\_P13\\_C06\\_S222\\_comb & tumor      \\\\\n",
       "\tHNSCC20\\_P13\\_C12\\_S228\\_comb & tumor      \\\\\n",
       "\tHNSCC17\\_P4\\_H04\\_S184\\_comb & tumor      \\\\\n",
       "\tHNSCC17\\_P4\\_C06\\_S126\\_comb & tumor      \\\\\n",
       "\tHNSCC20\\_P3\\_D01\\_S37\\_comb & tumor      \\\\\n",
       "\tHNSCC20\\_P3\\_D09\\_S45\\_comb & tumor      \\\\\n",
       "\tHNSCC17\\_P4\\_E06\\_S150\\_comb & tumor      \\\\\n",
       "\tHNSCC20\\_P13\\_H10\\_S286\\_comb & tumor      \\\\\n",
       "\tHNSCC17\\_P4\\_A02\\_S98\\_comb & tconv.cells\\\\\n",
       "\tHNSCC20\\_P13\\_D01\\_S229\\_comb & tumor      \\\\\n",
       "\tHNSCC20\\_P13\\_G02\\_S266\\_comb & tumor      \\\\\n",
       "\tHNSCC17\\_P4\\_B04\\_S112\\_comb & tumor      \\\\\n",
       "\tHNSCC17\\_P4\\_C09\\_S129\\_comb & tumor      \\\\\n",
       "\tHNSCC20\\_P13\\_A12\\_S204\\_comb & tumor      \\\\\n",
       "\tHNSCC17\\_P4\\_F06\\_S162\\_comb & tumor      \\\\\n",
       "\tHNSCC20\\_P3\\_B10\\_S22\\_comb & tumor      \\\\\n",
       "\tHNSCC20\\_P13\\_B11\\_S215\\_comb & tumor      \\\\\n",
       "\tHNSCC20\\_P3\\_C08\\_S32\\_comb & tumor      \\\\\n",
       "\tHNSCC17\\_P4\\_H03\\_S183\\_comb & tumor      \\\\\n",
       "\tHNSCC20\\_P3\\_F09\\_S69\\_comb & tumor      \\\\\n",
       "\tHNSCC17\\_P4\\_G12\\_S180\\_comb & tconv.cells\\\\\n",
       "\tHNSCC20\\_P13\\_C05\\_S221\\_comb & tumor      \\\\\n",
       "\tHNSCC17\\_P4\\_C12\\_S132\\_comb & tumor      \\\\\n",
       "\tHNSCC20\\_P3\\_H08\\_S92\\_comb & tumor      \\\\\n",
       "\tHNSCC20\\_P3\\_G06\\_S78\\_comb & tumor      \\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "A data.frame: 4484 × 1\n",
       "\n",
       "| <!--/--> | Ingest_prediction &lt;chr&gt; |\n",
       "|---|---|\n",
       "| HN28_P15_D06_S330_comb | Fibroblast  |\n",
       "| HN28_P6_G05_S173_comb | Fibroblast  |\n",
       "| HN26_P14_D11_S239_comb | tumor       |\n",
       "| HN26_P14_H05_S281_comb | Fibroblast  |\n",
       "| HN26_P25_H09_S189_comb | tumor       |\n",
       "| HN26_P14_H06_S282_comb | tumor       |\n",
       "| HN25_P25_C04_S316_comb | tumor       |\n",
       "| HN26_P25_A11_S107_comb | Fibroblast  |\n",
       "| HN26_P25_C09_S129_comb | tumor       |\n",
       "| HNSCC26_P24_H05_S377_comb | tumor       |\n",
       "| HN25_P5_E10_S58_comb | Fibroblast  |\n",
       "| HN25_P24_B02_S110_comb | tumor       |\n",
       "| HN25_P25_C01_S313_comb | tconv.cells |\n",
       "| HN28_P15_G06_S366_comb | Fibroblast  |\n",
       "| HN26_P6_B06_S18_comb | Fibroblast  |\n",
       "| HN25_P5_C05_S29_comb | Fibroblast  |\n",
       "| HN28_P6_D09_S141_comb | Fibroblast  |\n",
       "| HN26_P5_H01_S85_comb | tumor       |\n",
       "| HN26_P13_D07_S139_comb | Fibroblast  |\n",
       "| HN26_P5_E06_S54_comb | tumor       |\n",
       "| HN26_P26_H05_S377_comb | tumor       |\n",
       "| HNSCC26_P24_F12_S360_comb | tumor       |\n",
       "| HNSCC26_P24_F03_S351_comb | tumor       |\n",
       "| HN26_P6_D08_S44_comb | tumor       |\n",
       "| HN25_P5_E12_S60_comb | Fibroblast  |\n",
       "| HNSCC26_P24_C01_S313_comb | tumor       |\n",
       "| HN25_P5_F01_S61_comb | Fibroblast  |\n",
       "| HN26_P5_D12_S48_comb | Fibroblast  |\n",
       "| HN25_P25_C11_S323_comb | Fibroblast  |\n",
       "| HN25_P25_B12_S312_comb | tumor       |\n",
       "| ⋮ | ⋮ |\n",
       "| HNSCC17_P4_A08_S104_comb | tumor       |\n",
       "| HNSCC17_P4_E10_S154_comb | tumor       |\n",
       "| HNSCC17_P4_E02_S146_comb | tumor       |\n",
       "| HNSCC20_P13_F10_S262_comb | tumor       |\n",
       "| HNSCC17_P4_D04_S136_comb | tumor       |\n",
       "| HNSCC20_P13_C06_S222_comb | tumor       |\n",
       "| HNSCC20_P13_C12_S228_comb | tumor       |\n",
       "| HNSCC17_P4_H04_S184_comb | tumor       |\n",
       "| HNSCC17_P4_C06_S126_comb | tumor       |\n",
       "| HNSCC20_P3_D01_S37_comb | tumor       |\n",
       "| HNSCC20_P3_D09_S45_comb | tumor       |\n",
       "| HNSCC17_P4_E06_S150_comb | tumor       |\n",
       "| HNSCC20_P13_H10_S286_comb | tumor       |\n",
       "| HNSCC17_P4_A02_S98_comb | tconv.cells |\n",
       "| HNSCC20_P13_D01_S229_comb | tumor       |\n",
       "| HNSCC20_P13_G02_S266_comb | tumor       |\n",
       "| HNSCC17_P4_B04_S112_comb | tumor       |\n",
       "| HNSCC17_P4_C09_S129_comb | tumor       |\n",
       "| HNSCC20_P13_A12_S204_comb | tumor       |\n",
       "| HNSCC17_P4_F06_S162_comb | tumor       |\n",
       "| HNSCC20_P3_B10_S22_comb | tumor       |\n",
       "| HNSCC20_P13_B11_S215_comb | tumor       |\n",
       "| HNSCC20_P3_C08_S32_comb | tumor       |\n",
       "| HNSCC17_P4_H03_S183_comb | tumor       |\n",
       "| HNSCC20_P3_F09_S69_comb | tumor       |\n",
       "| HNSCC17_P4_G12_S180_comb | tconv.cells |\n",
       "| HNSCC20_P13_C05_S221_comb | tumor       |\n",
       "| HNSCC17_P4_C12_S132_comb | tumor       |\n",
       "| HNSCC20_P3_H08_S92_comb | tumor       |\n",
       "| HNSCC20_P3_G06_S78_comb | tumor       |\n",
       "\n"
      ],
      "text/plain": [
       "                          Ingest_prediction\n",
       "HN28_P15_D06_S330_comb    Fibroblast       \n",
       "HN28_P6_G05_S173_comb     Fibroblast       \n",
       "HN26_P14_D11_S239_comb    tumor            \n",
       "HN26_P14_H05_S281_comb    Fibroblast       \n",
       "HN26_P25_H09_S189_comb    tumor            \n",
       "HN26_P14_H06_S282_comb    tumor            \n",
       "HN25_P25_C04_S316_comb    tumor            \n",
       "HN26_P25_A11_S107_comb    Fibroblast       \n",
       "HN26_P25_C09_S129_comb    tumor            \n",
       "HNSCC26_P24_H05_S377_comb tumor            \n",
       "HN25_P5_E10_S58_comb      Fibroblast       \n",
       "HN25_P24_B02_S110_comb    tumor            \n",
       "HN25_P25_C01_S313_comb    tconv.cells      \n",
       "HN28_P15_G06_S366_comb    Fibroblast       \n",
       "HN26_P6_B06_S18_comb      Fibroblast       \n",
       "HN25_P5_C05_S29_comb      Fibroblast       \n",
       "HN28_P6_D09_S141_comb     Fibroblast       \n",
       "HN26_P5_H01_S85_comb      tumor            \n",
       "HN26_P13_D07_S139_comb    Fibroblast       \n",
       "HN26_P5_E06_S54_comb      tumor            \n",
       "HN26_P26_H05_S377_comb    tumor            \n",
       "HNSCC26_P24_F12_S360_comb tumor            \n",
       "HNSCC26_P24_F03_S351_comb tumor            \n",
       "HN26_P6_D08_S44_comb      tumor            \n",
       "HN25_P5_E12_S60_comb      Fibroblast       \n",
       "HNSCC26_P24_C01_S313_comb tumor            \n",
       "HN25_P5_F01_S61_comb      Fibroblast       \n",
       "HN26_P5_D12_S48_comb      Fibroblast       \n",
       "HN25_P25_C11_S323_comb    Fibroblast       \n",
       "HN25_P25_B12_S312_comb    tumor            \n",
       "⋮                         ⋮                \n",
       "HNSCC17_P4_A08_S104_comb  tumor            \n",
       "HNSCC17_P4_E10_S154_comb  tumor            \n",
       "HNSCC17_P4_E02_S146_comb  tumor            \n",
       "HNSCC20_P13_F10_S262_comb tumor            \n",
       "HNSCC17_P4_D04_S136_comb  tumor            \n",
       "HNSCC20_P13_C06_S222_comb tumor            \n",
       "HNSCC20_P13_C12_S228_comb tumor            \n",
       "HNSCC17_P4_H04_S184_comb  tumor            \n",
       "HNSCC17_P4_C06_S126_comb  tumor            \n",
       "HNSCC20_P3_D01_S37_comb   tumor            \n",
       "HNSCC20_P3_D09_S45_comb   tumor            \n",
       "HNSCC17_P4_E06_S150_comb  tumor            \n",
       "HNSCC20_P13_H10_S286_comb tumor            \n",
       "HNSCC17_P4_A02_S98_comb   tconv.cells      \n",
       "HNSCC20_P13_D01_S229_comb tumor            \n",
       "HNSCC20_P13_G02_S266_comb tumor            \n",
       "HNSCC17_P4_B04_S112_comb  tumor            \n",
       "HNSCC17_P4_C09_S129_comb  tumor            \n",
       "HNSCC20_P13_A12_S204_comb tumor            \n",
       "HNSCC17_P4_F06_S162_comb  tumor            \n",
       "HNSCC20_P3_B10_S22_comb   tumor            \n",
       "HNSCC20_P13_B11_S215_comb tumor            \n",
       "HNSCC20_P3_C08_S32_comb   tumor            \n",
       "HNSCC17_P4_H03_S183_comb  tumor            \n",
       "HNSCC20_P3_F09_S69_comb   tumor            \n",
       "HNSCC17_P4_G12_S180_comb  tconv.cells      \n",
       "HNSCC20_P13_C05_S221_comb tumor            \n",
       "HNSCC17_P4_C12_S132_comb  tumor            \n",
       "HNSCC20_P3_H08_S92_comb   tumor            \n",
       "HNSCC20_P3_G06_S78_comb   tumor            "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "label_subtype"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 28,
   "id": "97392f20",
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<style>\n",
       ".list-inline {list-style: none; margin:0; padding: 0}\n",
       ".list-inline>li {display: inline-block}\n",
       ".list-inline>li:not(:last-child)::after {content: \"\\00b7\"; padding: 0 .5ex}\n",
       "</style>\n",
       "<ol class=list-inline><li>'Fibroblast'</li><li>'tumor'</li><li>'tconv.cells'</li><li>'Macrophage'</li><li>'Endothelial'</li><li>'b.cells'</li><li>'cd14.cells'</li><li>'cd8.cells'</li><li>'treg.cells'</li><li>'mast.cells'</li><li>'pdc.cells'</li><li>'nk.cells'</li></ol>\n"
      ],
      "text/latex": [
       "\\begin{enumerate*}\n",
       "\\item 'Fibroblast'\n",
       "\\item 'tumor'\n",
       "\\item 'tconv.cells'\n",
       "\\item 'Macrophage'\n",
       "\\item 'Endothelial'\n",
       "\\item 'b.cells'\n",
       "\\item 'cd14.cells'\n",
       "\\item 'cd8.cells'\n",
       "\\item 'treg.cells'\n",
       "\\item 'mast.cells'\n",
       "\\item 'pdc.cells'\n",
       "\\item 'nk.cells'\n",
       "\\end{enumerate*}\n"
      ],
      "text/markdown": [
       "1. 'Fibroblast'\n",
       "2. 'tumor'\n",
       "3. 'tconv.cells'\n",
       "4. 'Macrophage'\n",
       "5. 'Endothelial'\n",
       "6. 'b.cells'\n",
       "7. 'cd14.cells'\n",
       "8. 'cd8.cells'\n",
       "9. 'treg.cells'\n",
       "10. 'mast.cells'\n",
       "11. 'pdc.cells'\n",
       "12. 'nk.cells'\n",
       "\n",
       "\n"
      ],
      "text/plain": [
       " [1] \"Fibroblast\"  \"tumor\"       \"tconv.cells\" \"Macrophage\"  \"Endothelial\"\n",
       " [6] \"b.cells\"     \"cd14.cells\"  \"cd8.cells\"   \"treg.cells\"  \"mast.cells\" \n",
       "[11] \"pdc.cells\"   \"nk.cells\"   "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "unique(label_subtype$Ingest_prediction)"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "f75bbc62",
   "metadata": {},
   "source": [
    "#### Run cleanup procedure, to remove \"RB\"=ribosomal genes; \"chrM\"=mitochondrial genes; \"chrX\" and \"chrY\" denoting genes on the sex chromosome.\n",
    "- 802  genes left, \n",
    "- 5318 single cells, 547 bulk samples\n",
    "- 9 celltypes (all tumors are same), 1 NA type"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 4,
   "id": "88005463",
   "metadata": {},
   "outputs": [],
   "source": [
    "?run.Ted"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 16,
   "id": "3ae160e4",
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "[1] \"Gene symbols detected. Cleaning up genes based on gene symbols. Recommend to use EMSEMBLE IDs for more unique mapping.\"\n",
      "A total of  33  genes from RB chrM chrX chrY  have been excluded \n",
      "A total of  0  lowly expressed genes have been excluded \n"
     ]
    }
   ],
   "source": [
    "ref.data.filtered <- cleanup.genes(ref.dat=df_Puram_filtered, gene.type=c(\"RB\",\"chrM\",\"chrX\",\"chrY\"), species=\"hs\", input.type=\"scRNA\",exp.cells=5)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 35,
   "id": "a8bd45ae",
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<table class=\"dataframe\">\n",
       "<caption>A matrix: 546 × 38929 of type dbl</caption>\n",
       "<thead>\n",
       "\t<tr><th></th><th scope=col>TSPAN6</th><th scope=col>TNMD</th><th scope=col>DPM1</th><th scope=col>SCYL3</th><th scope=col>C1orf112</th><th scope=col>FGR</th><th scope=col>CFH</th><th scope=col>FUCA2</th><th scope=col>GCLC</th><th scope=col>NFYA</th><th scope=col>⋯</th><th scope=col>LINC00550</th><th scope=col>LINC01394</th><th scope=col>LINC00602</th><th scope=col>MIR1291</th><th scope=col>LINC00891</th><th scope=col>PAUPAR</th><th scope=col>GIMAP1-GIMAP5</th><th scope=col>LINC02246</th><th scope=col>HERC2P7</th><th scope=col>LINC01144</th></tr>\n",
       "</thead>\n",
       "<tbody>\n",
       "\t<tr><th scope=row>TCGA-BB-4224-01A</th><td> 2237</td><td> 2</td><td>1606</td><td>1063</td><td>1208</td><td> 256</td><td>  177</td><td>2371</td><td> 2741</td><td>2515</td><td>⋯</td><td>6</td><td>7</td><td>0</td><td> 2</td><td>0</td><td>6</td><td>0</td><td>16</td><td>0</td><td>144</td></tr>\n",
       "\t<tr><th scope=row>TCGA-H7-7774-01A</th><td> 2740</td><td> 0</td><td>1691</td><td> 803</td><td> 317</td><td> 330</td><td> 5472</td><td>2316</td><td> 8370</td><td> 816</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td> 0</td><td>2</td><td>0</td><td>0</td><td> 6</td><td>0</td><td> 23</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6943-01A</th><td> 2686</td><td> 0</td><td>1649</td><td> 917</td><td> 402</td><td>1535</td><td>15358</td><td>3490</td><td> 4671</td><td>2080</td><td>⋯</td><td>0</td><td>4</td><td>0</td><td> 2</td><td>4</td><td>1</td><td>0</td><td>38</td><td>0</td><td> 18</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-5374-01A</th><td> 2086</td><td> 1</td><td>2333</td><td>1288</td><td>1105</td><td> 639</td><td> 5565</td><td>2065</td><td> 2902</td><td>1777</td><td>⋯</td><td>0</td><td>0</td><td>1</td><td> 0</td><td>3</td><td>0</td><td>0</td><td> 4</td><td>0</td><td> 31</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CQ-6227-01A</th><td>10167</td><td> 9</td><td>3021</td><td> 537</td><td> 459</td><td> 362</td><td> 6963</td><td>4883</td><td> 3140</td><td>2448</td><td>⋯</td><td>1</td><td>3</td><td>0</td><td> 0</td><td>2</td><td>0</td><td>0</td><td>15</td><td>0</td><td> 24</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6959-01A</th><td> 1154</td><td> 6</td><td>2766</td><td> 527</td><td> 747</td><td> 906</td><td>12856</td><td>6120</td><td> 7448</td><td>3527</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td> 1</td><td>3</td><td>1</td><td>0</td><td>19</td><td>1</td><td> 15</td></tr>\n",
       "\t<tr><th scope=row>TCGA-F7-A61V-01A</th><td> 1978</td><td> 1</td><td>1762</td><td> 482</td><td> 331</td><td> 147</td><td>  793</td><td>2364</td><td> 2827</td><td>1159</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td> 1</td><td>1</td><td>0</td><td>0</td><td>15</td><td>0</td><td> 20</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7413-01A</th><td> 1930</td><td> 1</td><td>1668</td><td> 671</td><td> 476</td><td> 477</td><td> 3669</td><td>3366</td><td> 2324</td><td>1459</td><td>⋯</td><td>0</td><td>3</td><td>0</td><td> 0</td><td>1</td><td>0</td><td>0</td><td>19</td><td>1</td><td> 23</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7247-01A</th><td> 1066</td><td> 1</td><td>1760</td><td> 600</td><td> 874</td><td> 204</td><td> 2791</td><td>1837</td><td> 9779</td><td>1916</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td> 0</td><td>1</td><td>0</td><td>0</td><td>17</td><td>1</td><td> 43</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CR-5249-01A</th><td> 2538</td><td> 0</td><td>1268</td><td>1066</td><td> 950</td><td> 924</td><td> 5289</td><td>2584</td><td> 2971</td><td>2572</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td> 4</td><td>6</td><td>0</td><td>0</td><td>17</td><td>1</td><td> 27</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CQ-5331-01A</th><td> 1465</td><td> 0</td><td>2612</td><td>1027</td><td> 766</td><td>1084</td><td>14982</td><td>5098</td><td> 7356</td><td>4672</td><td>⋯</td><td>0</td><td>1</td><td>1</td><td> 2</td><td>1</td><td>0</td><td>0</td><td>18</td><td>1</td><td> 58</td></tr>\n",
       "\t<tr><th scope=row>TCGA-BB-8601-01A</th><td> 1630</td><td> 1</td><td>1227</td><td> 764</td><td> 687</td><td>  42</td><td>  357</td><td>1270</td><td>19713</td><td>1255</td><td>⋯</td><td>1</td><td>0</td><td>0</td><td> 3</td><td>0</td><td>0</td><td>0</td><td> 6</td><td>0</td><td> 40</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-A45W-01A</th><td> 2215</td><td> 0</td><td>1139</td><td> 526</td><td> 464</td><td>1024</td><td> 1911</td><td>1741</td><td> 8343</td><td>1061</td><td>⋯</td><td>1</td><td>2</td><td>1</td><td> 3</td><td>4</td><td>0</td><td>0</td><td> 0</td><td>0</td><td> 43</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CQ-7063-01A</th><td>  724</td><td> 0</td><td>1220</td><td> 461</td><td> 235</td><td> 668</td><td> 4934</td><td>1323</td><td> 1859</td><td>1229</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td> 1</td><td>1</td><td>0</td><td>0</td><td> 6</td><td>0</td><td> 10</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-5373-01A</th><td>  718</td><td> 0</td><td>1162</td><td> 577</td><td> 232</td><td> 475</td><td> 6444</td><td>2164</td><td> 2870</td><td>1650</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td> 1</td><td>1</td><td>0</td><td>0</td><td>10</td><td>0</td><td>  8</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-A45T-01A</th><td> 2120</td><td> 3</td><td>2252</td><td> 614</td><td> 340</td><td> 700</td><td> 4178</td><td>1998</td><td> 1845</td><td>1197</td><td>⋯</td><td>0</td><td>4</td><td>0</td><td> 0</td><td>1</td><td>0</td><td>0</td><td> 3</td><td>0</td><td> 25</td></tr>\n",
       "\t<tr><th scope=row>TCGA-HD-A4C1-01A</th><td> 1273</td><td> 2</td><td>1793</td><td> 646</td><td> 461</td><td> 238</td><td> 4564</td><td>1802</td><td> 2617</td><td>1129</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td> 2</td><td>0</td><td>0</td><td>0</td><td>14</td><td>0</td><td>  2</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7438-11A</th><td> 4370</td><td> 3</td><td>2064</td><td> 648</td><td> 367</td><td> 444</td><td> 3991</td><td>1808</td><td> 3503</td><td>1599</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td> 0</td><td>0</td><td>0</td><td>0</td><td> 9</td><td>0</td><td> 32</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-5444-01A</th><td> 1011</td><td> 0</td><td>1488</td><td> 627</td><td> 366</td><td> 607</td><td> 5459</td><td>1695</td><td> 1224</td><td>1192</td><td>⋯</td><td>0</td><td>6</td><td>0</td><td> 0</td><td>1</td><td>0</td><td>0</td><td> 8</td><td>0</td><td> 36</td></tr>\n",
       "\t<tr><th scope=row>TCGA-BA-5556-01A</th><td> 1646</td><td> 1</td><td>2146</td><td> 763</td><td> 538</td><td> 967</td><td> 9401</td><td>2521</td><td> 3916</td><td>2173</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td> 1</td><td>1</td><td>0</td><td>0</td><td>24</td><td>0</td><td> 13</td></tr>\n",
       "\t<tr><th scope=row>TCGA-P3-A6SX-01A</th><td> 1421</td><td> 0</td><td>2413</td><td> 794</td><td> 986</td><td>  76</td><td>  563</td><td>2652</td><td> 1788</td><td>1105</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td> 0</td><td>0</td><td>0</td><td>0</td><td>17</td><td>0</td><td> 19</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7242-11A</th><td> 9952</td><td> 9</td><td>2403</td><td> 832</td><td> 437</td><td>1000</td><td> 6336</td><td>1563</td><td> 4157</td><td>1589</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td> 6</td><td>0</td><td>0</td><td>0</td><td> 7</td><td>0</td><td> 12</td></tr>\n",
       "\t<tr><th scope=row>TCGA-DQ-7592-01A</th><td> 2923</td><td> 0</td><td>2507</td><td> 794</td><td> 650</td><td> 484</td><td> 9116</td><td>3996</td><td> 4762</td><td>3113</td><td>⋯</td><td>0</td><td>5</td><td>1</td><td> 0</td><td>1</td><td>0</td><td>0</td><td>23</td><td>1</td><td> 30</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6937-01A</th><td> 1232</td><td> 2</td><td>1212</td><td> 503</td><td> 210</td><td> 286</td><td>  324</td><td>1607</td><td>  866</td><td>1250</td><td>⋯</td><td>0</td><td>2</td><td>0</td><td> 1</td><td>0</td><td>0</td><td>0</td><td> 3</td><td>0</td><td>111</td></tr>\n",
       "\t<tr><th scope=row>TCGA-QK-A8ZB-01A</th><td> 2332</td><td> 0</td><td>3280</td><td> 642</td><td> 507</td><td> 491</td><td> 5042</td><td>3292</td><td> 2676</td><td>2995</td><td>⋯</td><td>0</td><td>9</td><td>0</td><td>11</td><td>3</td><td>0</td><td>0</td><td> 1</td><td>0</td><td> 24</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7432-01A</th><td> 2032</td><td> 0</td><td>2069</td><td> 434</td><td>1081</td><td> 105</td><td> 3398</td><td>3988</td><td> 4089</td><td>2119</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td> 1</td><td>0</td><td>0</td><td>0</td><td>13</td><td>0</td><td>  4</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7089-01A</th><td> 3005</td><td> 0</td><td>2056</td><td> 601</td><td> 504</td><td> 392</td><td> 3379</td><td>3651</td><td> 2524</td><td>1731</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td> 2</td><td>0</td><td>0</td><td>0</td><td>18</td><td>0</td><td> 15</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6939-11A</th><td> 1612</td><td>53</td><td> 729</td><td> 488</td><td>  45</td><td> 155</td><td>10545</td><td>1223</td><td> 1011</td><td> 492</td><td>⋯</td><td>0</td><td>3</td><td>0</td><td> 0</td><td>3</td><td>1</td><td>0</td><td> 7</td><td>0</td><td> 68</td></tr>\n",
       "\t<tr><th scope=row>TCGA-BA-4075-01A</th><td> 2950</td><td> 1</td><td>5510</td><td> 355</td><td> 710</td><td> 306</td><td> 2114</td><td>2328</td><td> 2450</td><td>2342</td><td>⋯</td><td>0</td><td>3</td><td>1</td><td> 1</td><td>0</td><td>0</td><td>0</td><td>20</td><td>0</td><td> 10</td></tr>\n",
       "\t<tr><th scope=row>TCGA-T3-A92M-01A</th><td> 1679</td><td> 0</td><td>2430</td><td> 624</td><td> 759</td><td> 379</td><td> 2443</td><td>2379</td><td> 1900</td><td>1833</td><td>⋯</td><td>0</td><td>8</td><td>0</td><td> 3</td><td>1</td><td>0</td><td>0</td><td>12</td><td>0</td><td>113</td></tr>\n",
       "\t<tr><th scope=row>⋮</th><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋱</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7430-01A</th><td> 3632</td><td> 0</td><td>2857</td><td> 362</td><td> 389</td><td> 136</td><td> 606</td><td>3344</td><td>18448</td><td>1312</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>3</td><td>0</td><td>0</td><td>0</td><td>35</td><td>0</td><td> 4</td></tr>\n",
       "\t<tr><th scope=row>TCGA-D6-A74Q-01A</th><td> 2368</td><td> 0</td><td>3792</td><td> 765</td><td> 541</td><td> 307</td><td>1291</td><td>4462</td><td> 2878</td><td> 985</td><td>⋯</td><td>0</td><td>3</td><td>0</td><td>1</td><td>6</td><td>5</td><td>0</td><td>18</td><td>0</td><td>26</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7255-01A</th><td> 5443</td><td> 0</td><td>3542</td><td> 884</td><td> 979</td><td> 135</td><td>5880</td><td>5834</td><td> 2829</td><td>4707</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>21</td><td>0</td><td>19</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CQ-6223-01A</th><td> 1406</td><td> 1</td><td>1875</td><td> 623</td><td> 453</td><td> 555</td><td>3190</td><td>2858</td><td> 4875</td><td>1946</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td>1</td><td>0</td><td>0</td><td>0</td><td>17</td><td>0</td><td>50</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-A460-01A</th><td> 1049</td><td> 0</td><td>2070</td><td> 895</td><td> 853</td><td> 985</td><td>3735</td><td>1697</td><td> 7706</td><td>2500</td><td>⋯</td><td>0</td><td>6</td><td>0</td><td>2</td><td>4</td><td>0</td><td>0</td><td>10</td><td>0</td><td>25</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7261-01A</th><td> 2048</td><td> 2</td><td>1007</td><td> 750</td><td> 487</td><td> 493</td><td>1735</td><td>2226</td><td>13697</td><td>1659</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>1</td><td>0</td><td>0</td><td>11</td><td>1</td><td>21</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-4736-01A</th><td>  980</td><td>35</td><td>2072</td><td> 613</td><td> 287</td><td>2004</td><td>6050</td><td>3235</td><td>15570</td><td>1748</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td>1</td><td>2</td><td>0</td><td>0</td><td>12</td><td>1</td><td>20</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CR-7404-01A</th><td> 2646</td><td>18</td><td>2293</td><td>1259</td><td>1067</td><td>1147</td><td>6266</td><td>3687</td><td> 8930</td><td>3086</td><td>⋯</td><td>0</td><td>4</td><td>0</td><td>5</td><td>2</td><td>0</td><td>0</td><td> 6</td><td>0</td><td>99</td></tr>\n",
       "\t<tr><th scope=row>TCGA-UF-A719-01A</th><td> 5193</td><td> 0</td><td>1751</td><td>1275</td><td>1325</td><td> 203</td><td> 352</td><td>3428</td><td>27455</td><td>2397</td><td>⋯</td><td>0</td><td>2</td><td>0</td><td>1</td><td>1</td><td>0</td><td>0</td><td> 3</td><td>0</td><td>81</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7236-01A</th><td> 2366</td><td> 0</td><td>1862</td><td> 392</td><td> 367</td><td> 429</td><td>5933</td><td>2311</td><td> 4241</td><td>3022</td><td>⋯</td><td>0</td><td>1</td><td>1</td><td>0</td><td>1</td><td>0</td><td>0</td><td>32</td><td>0</td><td>22</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6951-01A</th><td> 3280</td><td> 1</td><td>1973</td><td> 904</td><td> 300</td><td> 111</td><td> 736</td><td>1844</td><td>15010</td><td>1314</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>19</td><td>0</td><td>44</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-4728-01A</th><td> 1136</td><td> 1</td><td>1739</td><td> 668</td><td> 347</td><td>2618</td><td>5170</td><td>2296</td><td> 2764</td><td>1537</td><td>⋯</td><td>0</td><td>3</td><td>1</td><td>1</td><td>5</td><td>0</td><td>0</td><td>10</td><td>1</td><td>12</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7090-01A</th><td> 1050</td><td> 3</td><td>1520</td><td> 464</td><td> 406</td><td> 698</td><td>2617</td><td>2863</td><td> 2464</td><td>1940</td><td>⋯</td><td>0</td><td>5</td><td>0</td><td>0</td><td>1</td><td>0</td><td>0</td><td>15</td><td>0</td><td> 8</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-5979-01A</th><td> 1416</td><td> 0</td><td>1383</td><td> 594</td><td> 517</td><td> 160</td><td>6088</td><td>5182</td><td> 3640</td><td>1324</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td>0</td><td> 8</td><td>0</td><td>17</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CQ-7069-01A</th><td>  728</td><td> 0</td><td>1603</td><td> 255</td><td> 165</td><td> 200</td><td>1027</td><td>1372</td><td>  796</td><td>1018</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>1</td><td>0</td><td>0</td><td>0</td><td> 6</td><td>0</td><td>10</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-4733-01A</th><td>  727</td><td> 1</td><td>1151</td><td> 481</td><td> 463</td><td> 934</td><td>6624</td><td>3854</td><td> 2812</td><td>1833</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>0</td><td>7</td><td>0</td><td>0</td><td> 9</td><td>0</td><td>10</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CR-7390-01A</th><td> 1995</td><td> 1</td><td>1561</td><td> 730</td><td> 594</td><td> 382</td><td>1708</td><td>2618</td><td>24128</td><td>2214</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td>1</td><td>0</td><td>0</td><td>0</td><td>15</td><td>0</td><td>32</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-A45X-01A</th><td> 1795</td><td> 1</td><td>1913</td><td> 977</td><td> 516</td><td> 211</td><td>1407</td><td>1556</td><td> 2578</td><td>1250</td><td>⋯</td><td>0</td><td>5</td><td>0</td><td>3</td><td>0</td><td>0</td><td>0</td><td> 9</td><td>0</td><td>14</td></tr>\n",
       "\t<tr><th scope=row>TCGA-IQ-A6SH-01A</th><td> 1428</td><td> 0</td><td>2404</td><td> 393</td><td> 334</td><td> 166</td><td>6937</td><td>3944</td><td> 7729</td><td>1394</td><td>⋯</td><td>0</td><td>3</td><td>0</td><td>0</td><td>3</td><td>1</td><td>0</td><td> 9</td><td>0</td><td>44</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6962-11A</th><td>11809</td><td> 4</td><td>1623</td><td> 981</td><td> 299</td><td> 281</td><td>9783</td><td>1691</td><td> 2135</td><td>1369</td><td>⋯</td><td>0</td><td>2</td><td>0</td><td>0</td><td>2</td><td>0</td><td>0</td><td> 8</td><td>0</td><td>41</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6960-11A</th><td> 3340</td><td> 0</td><td>1388</td><td> 608</td><td> 206</td><td> 304</td><td>6363</td><td>1242</td><td> 2100</td><td>1369</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td>2</td><td>1</td><td>0</td><td>0</td><td>12</td><td>0</td><td>19</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-A464-01A</th><td>  929</td><td> 2</td><td>2332</td><td> 472</td><td> 386</td><td> 331</td><td>7799</td><td>3028</td><td> 2494</td><td>1711</td><td>⋯</td><td>0</td><td>3</td><td>1</td><td>2</td><td>3</td><td>0</td><td>1</td><td> 1</td><td>0</td><td>46</td></tr>\n",
       "\t<tr><th scope=row>TCGA-C9-A47Z-01A</th><td> 1707</td><td> 0</td><td>1926</td><td> 410</td><td> 210</td><td> 134</td><td>1264</td><td>1356</td><td> 3710</td><td>1671</td><td>⋯</td><td>0</td><td>0</td><td>0</td><td>4</td><td>0</td><td>0</td><td>0</td><td>35</td><td>0</td><td>14</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-6010-01A</th><td> 2218</td><td> 0</td><td>1574</td><td> 852</td><td> 729</td><td> 550</td><td>5558</td><td>2921</td><td> 8749</td><td>1596</td><td>⋯</td><td>0</td><td>2</td><td>0</td><td>0</td><td>2</td><td>0</td><td>0</td><td>17</td><td>0</td><td>54</td></tr>\n",
       "\t<tr><th scope=row>TCGA-WA-A7GZ-11A</th><td> 2537</td><td>41</td><td>1171</td><td> 557</td><td> 127</td><td> 165</td><td>4651</td><td> 647</td><td> 3029</td><td> 848</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td>0</td><td>2</td><td>0</td><td>0</td><td>16</td><td>0</td><td>38</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7235-01A</th><td>  492</td><td> 0</td><td> 976</td><td> 376</td><td> 363</td><td> 488</td><td>5178</td><td>2138</td><td>20007</td><td>4131</td><td>⋯</td><td>0</td><td>2</td><td>2</td><td>1</td><td>0</td><td>0</td><td>0</td><td> 8</td><td>0</td><td>60</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CX-7086-01A</th><td> 2741</td><td> 0</td><td>1952</td><td>1003</td><td>1103</td><td> 214</td><td>1809</td><td>2639</td><td>13623</td><td>2530</td><td>⋯</td><td>2</td><td>2</td><td>0</td><td>1</td><td>0</td><td>1</td><td>0</td><td>11</td><td>0</td><td>77</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6935-11A</th><td> 8492</td><td> 3</td><td>1578</td><td> 818</td><td> 281</td><td> 419</td><td>7368</td><td>1355</td><td> 2276</td><td>1583</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td>1</td><td>0</td><td>0</td><td>0</td><td>12</td><td>0</td><td>19</td></tr>\n",
       "\t<tr><th scope=row>TCGA-P3-A6SW-01A</th><td>  770</td><td> 1</td><td>1569</td><td> 620</td><td> 591</td><td> 462</td><td>2082</td><td>1603</td><td>31675</td><td>1473</td><td>⋯</td><td>0</td><td>0</td><td>2</td><td>1</td><td>1</td><td>0</td><td>0</td><td> 0</td><td>1</td><td>22</td></tr>\n",
       "\t<tr><th scope=row>TCGA-HD-A6HZ-01A</th><td>  923</td><td> 0</td><td>1183</td><td> 607</td><td> 344</td><td> 925</td><td>2482</td><td>1769</td><td> 3949</td><td> 899</td><td>⋯</td><td>0</td><td>1</td><td>0</td><td>0</td><td>1</td><td>0</td><td>0</td><td>11</td><td>1</td><td>40</td></tr>\n",
       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "A matrix: 546 × 38929 of type dbl\n",
       "\\begin{tabular}{r|lllllllllllllllllllll}\n",
       "  & TSPAN6 & TNMD & DPM1 & SCYL3 & C1orf112 & FGR & CFH & FUCA2 & GCLC & NFYA & ⋯ & LINC00550 & LINC01394 & LINC00602 & MIR1291 & LINC00891 & PAUPAR & GIMAP1-GIMAP5 & LINC02246 & HERC2P7 & LINC01144\\\\\n",
       "\\hline\n",
       "\tTCGA-BB-4224-01A &  2237 &  2 & 1606 & 1063 & 1208 &  256 &   177 & 2371 &  2741 & 2515 & ⋯ & 6 & 7 & 0 &  2 & 0 & 6 & 0 & 16 & 0 & 144\\\\\n",
       "\tTCGA-H7-7774-01A &  2740 &  0 & 1691 &  803 &  317 &  330 &  5472 & 2316 &  8370 &  816 & ⋯ & 0 & 1 & 0 &  0 & 2 & 0 & 0 &  6 & 0 &  23\\\\\n",
       "\tTCGA-CV-6943-01A &  2686 &  0 & 1649 &  917 &  402 & 1535 & 15358 & 3490 &  4671 & 2080 & ⋯ & 0 & 4 & 0 &  2 & 4 & 1 & 0 & 38 & 0 &  18\\\\\n",
       "\tTCGA-CN-5374-01A &  2086 &  1 & 2333 & 1288 & 1105 &  639 &  5565 & 2065 &  2902 & 1777 & ⋯ & 0 & 0 & 1 &  0 & 3 & 0 & 0 &  4 & 0 &  31\\\\\n",
       "\tTCGA-CQ-6227-01A & 10167 &  9 & 3021 &  537 &  459 &  362 &  6963 & 4883 &  3140 & 2448 & ⋯ & 1 & 3 & 0 &  0 & 2 & 0 & 0 & 15 & 0 &  24\\\\\n",
       "\tTCGA-CV-6959-01A &  1154 &  6 & 2766 &  527 &  747 &  906 & 12856 & 6120 &  7448 & 3527 & ⋯ & 0 & 1 & 0 &  1 & 3 & 1 & 0 & 19 & 1 &  15\\\\\n",
       "\tTCGA-F7-A61V-01A &  1978 &  1 & 1762 &  482 &  331 &  147 &   793 & 2364 &  2827 & 1159 & ⋯ & 0 & 0 & 0 &  1 & 1 & 0 & 0 & 15 & 0 &  20\\\\\n",
       "\tTCGA-CV-7413-01A &  1930 &  1 & 1668 &  671 &  476 &  477 &  3669 & 3366 &  2324 & 1459 & ⋯ & 0 & 3 & 0 &  0 & 1 & 0 & 0 & 19 & 1 &  23\\\\\n",
       "\tTCGA-CV-7247-01A &  1066 &  1 & 1760 &  600 &  874 &  204 &  2791 & 1837 &  9779 & 1916 & ⋯ & 0 & 0 & 0 &  0 & 1 & 0 & 0 & 17 & 1 &  43\\\\\n",
       "\tTCGA-CR-5249-01A &  2538 &  0 & 1268 & 1066 &  950 &  924 &  5289 & 2584 &  2971 & 2572 & ⋯ & 0 & 0 & 0 &  4 & 6 & 0 & 0 & 17 & 1 &  27\\\\\n",
       "\tTCGA-CQ-5331-01A &  1465 &  0 & 2612 & 1027 &  766 & 1084 & 14982 & 5098 &  7356 & 4672 & ⋯ & 0 & 1 & 1 &  2 & 1 & 0 & 0 & 18 & 1 &  58\\\\\n",
       "\tTCGA-BB-8601-01A &  1630 &  1 & 1227 &  764 &  687 &   42 &   357 & 1270 & 19713 & 1255 & ⋯ & 1 & 0 & 0 &  3 & 0 & 0 & 0 &  6 & 0 &  40\\\\\n",
       "\tTCGA-CV-A45W-01A &  2215 &  0 & 1139 &  526 &  464 & 1024 &  1911 & 1741 &  8343 & 1061 & ⋯ & 1 & 2 & 1 &  3 & 4 & 0 & 0 &  0 & 0 &  43\\\\\n",
       "\tTCGA-CQ-7063-01A &   724 &  0 & 1220 &  461 &  235 &  668 &  4934 & 1323 &  1859 & 1229 & ⋯ & 0 & 0 & 0 &  1 & 1 & 0 & 0 &  6 & 0 &  10\\\\\n",
       "\tTCGA-CN-5373-01A &   718 &  0 & 1162 &  577 &  232 &  475 &  6444 & 2164 &  2870 & 1650 & ⋯ & 0 & 0 & 0 &  1 & 1 & 0 & 0 & 10 & 0 &   8\\\\\n",
       "\tTCGA-CV-A45T-01A &  2120 &  3 & 2252 &  614 &  340 &  700 &  4178 & 1998 &  1845 & 1197 & ⋯ & 0 & 4 & 0 &  0 & 1 & 0 & 0 &  3 & 0 &  25\\\\\n",
       "\tTCGA-HD-A4C1-01A &  1273 &  2 & 1793 &  646 &  461 &  238 &  4564 & 1802 &  2617 & 1129 & ⋯ & 0 & 1 & 0 &  2 & 0 & 0 & 0 & 14 & 0 &   2\\\\\n",
       "\tTCGA-CV-7438-11A &  4370 &  3 & 2064 &  648 &  367 &  444 &  3991 & 1808 &  3503 & 1599 & ⋯ & 0 & 0 & 0 &  0 & 0 & 0 & 0 &  9 & 0 &  32\\\\\n",
       "\tTCGA-CV-5444-01A &  1011 &  0 & 1488 &  627 &  366 &  607 &  5459 & 1695 &  1224 & 1192 & ⋯ & 0 & 6 & 0 &  0 & 1 & 0 & 0 &  8 & 0 &  36\\\\\n",
       "\tTCGA-BA-5556-01A &  1646 &  1 & 2146 &  763 &  538 &  967 &  9401 & 2521 &  3916 & 2173 & ⋯ & 0 & 1 & 0 &  1 & 1 & 0 & 0 & 24 & 0 &  13\\\\\n",
       "\tTCGA-P3-A6SX-01A &  1421 &  0 & 2413 &  794 &  986 &   76 &   563 & 2652 &  1788 & 1105 & ⋯ & 0 & 0 & 0 &  0 & 0 & 0 & 0 & 17 & 0 &  19\\\\\n",
       "\tTCGA-CV-7242-11A &  9952 &  9 & 2403 &  832 &  437 & 1000 &  6336 & 1563 &  4157 & 1589 & ⋯ & 0 & 0 & 0 &  6 & 0 & 0 & 0 &  7 & 0 &  12\\\\\n",
       "\tTCGA-DQ-7592-01A &  2923 &  0 & 2507 &  794 &  650 &  484 &  9116 & 3996 &  4762 & 3113 & ⋯ & 0 & 5 & 1 &  0 & 1 & 0 & 0 & 23 & 1 &  30\\\\\n",
       "\tTCGA-CV-6937-01A &  1232 &  2 & 1212 &  503 &  210 &  286 &   324 & 1607 &   866 & 1250 & ⋯ & 0 & 2 & 0 &  1 & 0 & 0 & 0 &  3 & 0 & 111\\\\\n",
       "\tTCGA-QK-A8ZB-01A &  2332 &  0 & 3280 &  642 &  507 &  491 &  5042 & 3292 &  2676 & 2995 & ⋯ & 0 & 9 & 0 & 11 & 3 & 0 & 0 &  1 & 0 &  24\\\\\n",
       "\tTCGA-CV-7432-01A &  2032 &  0 & 2069 &  434 & 1081 &  105 &  3398 & 3988 &  4089 & 2119 & ⋯ & 0 & 1 & 0 &  1 & 0 & 0 & 0 & 13 & 0 &   4\\\\\n",
       "\tTCGA-CV-7089-01A &  3005 &  0 & 2056 &  601 &  504 &  392 &  3379 & 3651 &  2524 & 1731 & ⋯ & 0 & 0 & 0 &  2 & 0 & 0 & 0 & 18 & 0 &  15\\\\\n",
       "\tTCGA-CV-6939-11A &  1612 & 53 &  729 &  488 &   45 &  155 & 10545 & 1223 &  1011 &  492 & ⋯ & 0 & 3 & 0 &  0 & 3 & 1 & 0 &  7 & 0 &  68\\\\\n",
       "\tTCGA-BA-4075-01A &  2950 &  1 & 5510 &  355 &  710 &  306 &  2114 & 2328 &  2450 & 2342 & ⋯ & 0 & 3 & 1 &  1 & 0 & 0 & 0 & 20 & 0 &  10\\\\\n",
       "\tTCGA-T3-A92M-01A &  1679 &  0 & 2430 &  624 &  759 &  379 &  2443 & 2379 &  1900 & 1833 & ⋯ & 0 & 8 & 0 &  3 & 1 & 0 & 0 & 12 & 0 & 113\\\\\n",
       "\t⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋱ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮\\\\\n",
       "\tTCGA-CV-7430-01A &  3632 &  0 & 2857 &  362 &  389 &  136 &  606 & 3344 & 18448 & 1312 & ⋯ & 0 & 0 & 0 & 3 & 0 & 0 & 0 & 35 & 0 &  4\\\\\n",
       "\tTCGA-D6-A74Q-01A &  2368 &  0 & 3792 &  765 &  541 &  307 & 1291 & 4462 &  2878 &  985 & ⋯ & 0 & 3 & 0 & 1 & 6 & 5 & 0 & 18 & 0 & 26\\\\\n",
       "\tTCGA-CV-7255-01A &  5443 &  0 & 3542 &  884 &  979 &  135 & 5880 & 5834 &  2829 & 4707 & ⋯ & 0 & 1 & 0 & 0 & 0 & 0 & 0 & 21 & 0 & 19\\\\\n",
       "\tTCGA-CQ-6223-01A &  1406 &  1 & 1875 &  623 &  453 &  555 & 3190 & 2858 &  4875 & 1946 & ⋯ & 0 & 1 & 0 & 1 & 0 & 0 & 0 & 17 & 0 & 50\\\\\n",
       "\tTCGA-CV-A460-01A &  1049 &  0 & 2070 &  895 &  853 &  985 & 3735 & 1697 &  7706 & 2500 & ⋯ & 0 & 6 & 0 & 2 & 4 & 0 & 0 & 10 & 0 & 25\\\\\n",
       "\tTCGA-CV-7261-01A &  2048 &  2 & 1007 &  750 &  487 &  493 & 1735 & 2226 & 13697 & 1659 & ⋯ & 0 & 0 & 0 & 0 & 1 & 0 & 0 & 11 & 1 & 21\\\\\n",
       "\tTCGA-CN-4736-01A &   980 & 35 & 2072 &  613 &  287 & 2004 & 6050 & 3235 & 15570 & 1748 & ⋯ & 0 & 1 & 0 & 1 & 2 & 0 & 0 & 12 & 1 & 20\\\\\n",
       "\tTCGA-CR-7404-01A &  2646 & 18 & 2293 & 1259 & 1067 & 1147 & 6266 & 3687 &  8930 & 3086 & ⋯ & 0 & 4 & 0 & 5 & 2 & 0 & 0 &  6 & 0 & 99\\\\\n",
       "\tTCGA-UF-A719-01A &  5193 &  0 & 1751 & 1275 & 1325 &  203 &  352 & 3428 & 27455 & 2397 & ⋯ & 0 & 2 & 0 & 1 & 1 & 0 & 0 &  3 & 0 & 81\\\\\n",
       "\tTCGA-CV-7236-01A &  2366 &  0 & 1862 &  392 &  367 &  429 & 5933 & 2311 &  4241 & 3022 & ⋯ & 0 & 1 & 1 & 0 & 1 & 0 & 0 & 32 & 0 & 22\\\\\n",
       "\tTCGA-CV-6951-01A &  3280 &  1 & 1973 &  904 &  300 &  111 &  736 & 1844 & 15010 & 1314 & ⋯ & 0 & 1 & 0 & 0 & 0 & 0 & 0 & 19 & 0 & 44\\\\\n",
       "\tTCGA-CN-4728-01A &  1136 &  1 & 1739 &  668 &  347 & 2618 & 5170 & 2296 &  2764 & 1537 & ⋯ & 0 & 3 & 1 & 1 & 5 & 0 & 0 & 10 & 1 & 12\\\\\n",
       "\tTCGA-CV-7090-01A &  1050 &  3 & 1520 &  464 &  406 &  698 & 2617 & 2863 &  2464 & 1940 & ⋯ & 0 & 5 & 0 & 0 & 1 & 0 & 0 & 15 & 0 &  8\\\\\n",
       "\tTCGA-CV-5979-01A &  1416 &  0 & 1383 &  594 &  517 &  160 & 6088 & 5182 &  3640 & 1324 & ⋯ & 0 & 0 & 0 & 0 & 0 & 0 & 0 &  8 & 0 & 17\\\\\n",
       "\tTCGA-CQ-7069-01A &   728 &  0 & 1603 &  255 &  165 &  200 & 1027 & 1372 &   796 & 1018 & ⋯ & 0 & 0 & 0 & 1 & 0 & 0 & 0 &  6 & 0 & 10\\\\\n",
       "\tTCGA-CN-4733-01A &   727 &  1 & 1151 &  481 &  463 &  934 & 6624 & 3854 &  2812 & 1833 & ⋯ & 0 & 0 & 0 & 0 & 7 & 0 & 0 &  9 & 0 & 10\\\\\n",
       "\tTCGA-CR-7390-01A &  1995 &  1 & 1561 &  730 &  594 &  382 & 1708 & 2618 & 24128 & 2214 & ⋯ & 0 & 1 & 0 & 1 & 0 & 0 & 0 & 15 & 0 & 32\\\\\n",
       "\tTCGA-CV-A45X-01A &  1795 &  1 & 1913 &  977 &  516 &  211 & 1407 & 1556 &  2578 & 1250 & ⋯ & 0 & 5 & 0 & 3 & 0 & 0 & 0 &  9 & 0 & 14\\\\\n",
       "\tTCGA-IQ-A6SH-01A &  1428 &  0 & 2404 &  393 &  334 &  166 & 6937 & 3944 &  7729 & 1394 & ⋯ & 0 & 3 & 0 & 0 & 3 & 1 & 0 &  9 & 0 & 44\\\\\n",
       "\tTCGA-CV-6962-11A & 11809 &  4 & 1623 &  981 &  299 &  281 & 9783 & 1691 &  2135 & 1369 & ⋯ & 0 & 2 & 0 & 0 & 2 & 0 & 0 &  8 & 0 & 41\\\\\n",
       "\tTCGA-CV-6960-11A &  3340 &  0 & 1388 &  608 &  206 &  304 & 6363 & 1242 &  2100 & 1369 & ⋯ & 0 & 1 & 0 & 2 & 1 & 0 & 0 & 12 & 0 & 19\\\\\n",
       "\tTCGA-CV-A464-01A &   929 &  2 & 2332 &  472 &  386 &  331 & 7799 & 3028 &  2494 & 1711 & ⋯ & 0 & 3 & 1 & 2 & 3 & 0 & 1 &  1 & 0 & 46\\\\\n",
       "\tTCGA-C9-A47Z-01A &  1707 &  0 & 1926 &  410 &  210 &  134 & 1264 & 1356 &  3710 & 1671 & ⋯ & 0 & 0 & 0 & 4 & 0 & 0 & 0 & 35 & 0 & 14\\\\\n",
       "\tTCGA-CN-6010-01A &  2218 &  0 & 1574 &  852 &  729 &  550 & 5558 & 2921 &  8749 & 1596 & ⋯ & 0 & 2 & 0 & 0 & 2 & 0 & 0 & 17 & 0 & 54\\\\\n",
       "\tTCGA-WA-A7GZ-11A &  2537 & 41 & 1171 &  557 &  127 &  165 & 4651 &  647 &  3029 &  848 & ⋯ & 0 & 1 & 0 & 0 & 2 & 0 & 0 & 16 & 0 & 38\\\\\n",
       "\tTCGA-CV-7235-01A &   492 &  0 &  976 &  376 &  363 &  488 & 5178 & 2138 & 20007 & 4131 & ⋯ & 0 & 2 & 2 & 1 & 0 & 0 & 0 &  8 & 0 & 60\\\\\n",
       "\tTCGA-CX-7086-01A &  2741 &  0 & 1952 & 1003 & 1103 &  214 & 1809 & 2639 & 13623 & 2530 & ⋯ & 2 & 2 & 0 & 1 & 0 & 1 & 0 & 11 & 0 & 77\\\\\n",
       "\tTCGA-CV-6935-11A &  8492 &  3 & 1578 &  818 &  281 &  419 & 7368 & 1355 &  2276 & 1583 & ⋯ & 0 & 1 & 0 & 1 & 0 & 0 & 0 & 12 & 0 & 19\\\\\n",
       "\tTCGA-P3-A6SW-01A &   770 &  1 & 1569 &  620 &  591 &  462 & 2082 & 1603 & 31675 & 1473 & ⋯ & 0 & 0 & 2 & 1 & 1 & 0 & 0 &  0 & 1 & 22\\\\\n",
       "\tTCGA-HD-A6HZ-01A &   923 &  0 & 1183 &  607 &  344 &  925 & 2482 & 1769 &  3949 &  899 & ⋯ & 0 & 1 & 0 & 0 & 1 & 0 & 0 & 11 & 1 & 40\\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "A matrix: 546 × 38929 of type dbl\n",
       "\n",
       "| <!--/--> | TSPAN6 | TNMD | DPM1 | SCYL3 | C1orf112 | FGR | CFH | FUCA2 | GCLC | NFYA | ⋯ | LINC00550 | LINC01394 | LINC00602 | MIR1291 | LINC00891 | PAUPAR | GIMAP1-GIMAP5 | LINC02246 | HERC2P7 | LINC01144 |\n",
       "|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|\n",
       "| TCGA-BB-4224-01A |  2237 |  2 | 1606 | 1063 | 1208 |  256 |   177 | 2371 |  2741 | 2515 | ⋯ | 6 | 7 | 0 |  2 | 0 | 6 | 0 | 16 | 0 | 144 |\n",
       "| TCGA-H7-7774-01A |  2740 |  0 | 1691 |  803 |  317 |  330 |  5472 | 2316 |  8370 |  816 | ⋯ | 0 | 1 | 0 |  0 | 2 | 0 | 0 |  6 | 0 |  23 |\n",
       "| TCGA-CV-6943-01A |  2686 |  0 | 1649 |  917 |  402 | 1535 | 15358 | 3490 |  4671 | 2080 | ⋯ | 0 | 4 | 0 |  2 | 4 | 1 | 0 | 38 | 0 |  18 |\n",
       "| TCGA-CN-5374-01A |  2086 |  1 | 2333 | 1288 | 1105 |  639 |  5565 | 2065 |  2902 | 1777 | ⋯ | 0 | 0 | 1 |  0 | 3 | 0 | 0 |  4 | 0 |  31 |\n",
       "| TCGA-CQ-6227-01A | 10167 |  9 | 3021 |  537 |  459 |  362 |  6963 | 4883 |  3140 | 2448 | ⋯ | 1 | 3 | 0 |  0 | 2 | 0 | 0 | 15 | 0 |  24 |\n",
       "| TCGA-CV-6959-01A |  1154 |  6 | 2766 |  527 |  747 |  906 | 12856 | 6120 |  7448 | 3527 | ⋯ | 0 | 1 | 0 |  1 | 3 | 1 | 0 | 19 | 1 |  15 |\n",
       "| TCGA-F7-A61V-01A |  1978 |  1 | 1762 |  482 |  331 |  147 |   793 | 2364 |  2827 | 1159 | ⋯ | 0 | 0 | 0 |  1 | 1 | 0 | 0 | 15 | 0 |  20 |\n",
       "| TCGA-CV-7413-01A |  1930 |  1 | 1668 |  671 |  476 |  477 |  3669 | 3366 |  2324 | 1459 | ⋯ | 0 | 3 | 0 |  0 | 1 | 0 | 0 | 19 | 1 |  23 |\n",
       "| TCGA-CV-7247-01A |  1066 |  1 | 1760 |  600 |  874 |  204 |  2791 | 1837 |  9779 | 1916 | ⋯ | 0 | 0 | 0 |  0 | 1 | 0 | 0 | 17 | 1 |  43 |\n",
       "| TCGA-CR-5249-01A |  2538 |  0 | 1268 | 1066 |  950 |  924 |  5289 | 2584 |  2971 | 2572 | ⋯ | 0 | 0 | 0 |  4 | 6 | 0 | 0 | 17 | 1 |  27 |\n",
       "| TCGA-CQ-5331-01A |  1465 |  0 | 2612 | 1027 |  766 | 1084 | 14982 | 5098 |  7356 | 4672 | ⋯ | 0 | 1 | 1 |  2 | 1 | 0 | 0 | 18 | 1 |  58 |\n",
       "| TCGA-BB-8601-01A |  1630 |  1 | 1227 |  764 |  687 |   42 |   357 | 1270 | 19713 | 1255 | ⋯ | 1 | 0 | 0 |  3 | 0 | 0 | 0 |  6 | 0 |  40 |\n",
       "| TCGA-CV-A45W-01A |  2215 |  0 | 1139 |  526 |  464 | 1024 |  1911 | 1741 |  8343 | 1061 | ⋯ | 1 | 2 | 1 |  3 | 4 | 0 | 0 |  0 | 0 |  43 |\n",
       "| TCGA-CQ-7063-01A |   724 |  0 | 1220 |  461 |  235 |  668 |  4934 | 1323 |  1859 | 1229 | ⋯ | 0 | 0 | 0 |  1 | 1 | 0 | 0 |  6 | 0 |  10 |\n",
       "| TCGA-CN-5373-01A |   718 |  0 | 1162 |  577 |  232 |  475 |  6444 | 2164 |  2870 | 1650 | ⋯ | 0 | 0 | 0 |  1 | 1 | 0 | 0 | 10 | 0 |   8 |\n",
       "| TCGA-CV-A45T-01A |  2120 |  3 | 2252 |  614 |  340 |  700 |  4178 | 1998 |  1845 | 1197 | ⋯ | 0 | 4 | 0 |  0 | 1 | 0 | 0 |  3 | 0 |  25 |\n",
       "| TCGA-HD-A4C1-01A |  1273 |  2 | 1793 |  646 |  461 |  238 |  4564 | 1802 |  2617 | 1129 | ⋯ | 0 | 1 | 0 |  2 | 0 | 0 | 0 | 14 | 0 |   2 |\n",
       "| TCGA-CV-7438-11A |  4370 |  3 | 2064 |  648 |  367 |  444 |  3991 | 1808 |  3503 | 1599 | ⋯ | 0 | 0 | 0 |  0 | 0 | 0 | 0 |  9 | 0 |  32 |\n",
       "| TCGA-CV-5444-01A |  1011 |  0 | 1488 |  627 |  366 |  607 |  5459 | 1695 |  1224 | 1192 | ⋯ | 0 | 6 | 0 |  0 | 1 | 0 | 0 |  8 | 0 |  36 |\n",
       "| TCGA-BA-5556-01A |  1646 |  1 | 2146 |  763 |  538 |  967 |  9401 | 2521 |  3916 | 2173 | ⋯ | 0 | 1 | 0 |  1 | 1 | 0 | 0 | 24 | 0 |  13 |\n",
       "| TCGA-P3-A6SX-01A |  1421 |  0 | 2413 |  794 |  986 |   76 |   563 | 2652 |  1788 | 1105 | ⋯ | 0 | 0 | 0 |  0 | 0 | 0 | 0 | 17 | 0 |  19 |\n",
       "| TCGA-CV-7242-11A |  9952 |  9 | 2403 |  832 |  437 | 1000 |  6336 | 1563 |  4157 | 1589 | ⋯ | 0 | 0 | 0 |  6 | 0 | 0 | 0 |  7 | 0 |  12 |\n",
       "| TCGA-DQ-7592-01A |  2923 |  0 | 2507 |  794 |  650 |  484 |  9116 | 3996 |  4762 | 3113 | ⋯ | 0 | 5 | 1 |  0 | 1 | 0 | 0 | 23 | 1 |  30 |\n",
       "| TCGA-CV-6937-01A |  1232 |  2 | 1212 |  503 |  210 |  286 |   324 | 1607 |   866 | 1250 | ⋯ | 0 | 2 | 0 |  1 | 0 | 0 | 0 |  3 | 0 | 111 |\n",
       "| TCGA-QK-A8ZB-01A |  2332 |  0 | 3280 |  642 |  507 |  491 |  5042 | 3292 |  2676 | 2995 | ⋯ | 0 | 9 | 0 | 11 | 3 | 0 | 0 |  1 | 0 |  24 |\n",
       "| TCGA-CV-7432-01A |  2032 |  0 | 2069 |  434 | 1081 |  105 |  3398 | 3988 |  4089 | 2119 | ⋯ | 0 | 1 | 0 |  1 | 0 | 0 | 0 | 13 | 0 |   4 |\n",
       "| TCGA-CV-7089-01A |  3005 |  0 | 2056 |  601 |  504 |  392 |  3379 | 3651 |  2524 | 1731 | ⋯ | 0 | 0 | 0 |  2 | 0 | 0 | 0 | 18 | 0 |  15 |\n",
       "| TCGA-CV-6939-11A |  1612 | 53 |  729 |  488 |   45 |  155 | 10545 | 1223 |  1011 |  492 | ⋯ | 0 | 3 | 0 |  0 | 3 | 1 | 0 |  7 | 0 |  68 |\n",
       "| TCGA-BA-4075-01A |  2950 |  1 | 5510 |  355 |  710 |  306 |  2114 | 2328 |  2450 | 2342 | ⋯ | 0 | 3 | 1 |  1 | 0 | 0 | 0 | 20 | 0 |  10 |\n",
       "| TCGA-T3-A92M-01A |  1679 |  0 | 2430 |  624 |  759 |  379 |  2443 | 2379 |  1900 | 1833 | ⋯ | 0 | 8 | 0 |  3 | 1 | 0 | 0 | 12 | 0 | 113 |\n",
       "| ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋱ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ |\n",
       "| TCGA-CV-7430-01A |  3632 |  0 | 2857 |  362 |  389 |  136 |  606 | 3344 | 18448 | 1312 | ⋯ | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 35 | 0 |  4 |\n",
       "| TCGA-D6-A74Q-01A |  2368 |  0 | 3792 |  765 |  541 |  307 | 1291 | 4462 |  2878 |  985 | ⋯ | 0 | 3 | 0 | 1 | 6 | 5 | 0 | 18 | 0 | 26 |\n",
       "| TCGA-CV-7255-01A |  5443 |  0 | 3542 |  884 |  979 |  135 | 5880 | 5834 |  2829 | 4707 | ⋯ | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 21 | 0 | 19 |\n",
       "| TCGA-CQ-6223-01A |  1406 |  1 | 1875 |  623 |  453 |  555 | 3190 | 2858 |  4875 | 1946 | ⋯ | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 17 | 0 | 50 |\n",
       "| TCGA-CV-A460-01A |  1049 |  0 | 2070 |  895 |  853 |  985 | 3735 | 1697 |  7706 | 2500 | ⋯ | 0 | 6 | 0 | 2 | 4 | 0 | 0 | 10 | 0 | 25 |\n",
       "| TCGA-CV-7261-01A |  2048 |  2 | 1007 |  750 |  487 |  493 | 1735 | 2226 | 13697 | 1659 | ⋯ | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 11 | 1 | 21 |\n",
       "| TCGA-CN-4736-01A |   980 | 35 | 2072 |  613 |  287 | 2004 | 6050 | 3235 | 15570 | 1748 | ⋯ | 0 | 1 | 0 | 1 | 2 | 0 | 0 | 12 | 1 | 20 |\n",
       "| TCGA-CR-7404-01A |  2646 | 18 | 2293 | 1259 | 1067 | 1147 | 6266 | 3687 |  8930 | 3086 | ⋯ | 0 | 4 | 0 | 5 | 2 | 0 | 0 |  6 | 0 | 99 |\n",
       "| TCGA-UF-A719-01A |  5193 |  0 | 1751 | 1275 | 1325 |  203 |  352 | 3428 | 27455 | 2397 | ⋯ | 0 | 2 | 0 | 1 | 1 | 0 | 0 |  3 | 0 | 81 |\n",
       "| TCGA-CV-7236-01A |  2366 |  0 | 1862 |  392 |  367 |  429 | 5933 | 2311 |  4241 | 3022 | ⋯ | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 32 | 0 | 22 |\n",
       "| TCGA-CV-6951-01A |  3280 |  1 | 1973 |  904 |  300 |  111 |  736 | 1844 | 15010 | 1314 | ⋯ | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 19 | 0 | 44 |\n",
       "| TCGA-CN-4728-01A |  1136 |  1 | 1739 |  668 |  347 | 2618 | 5170 | 2296 |  2764 | 1537 | ⋯ | 0 | 3 | 1 | 1 | 5 | 0 | 0 | 10 | 1 | 12 |\n",
       "| TCGA-CV-7090-01A |  1050 |  3 | 1520 |  464 |  406 |  698 | 2617 | 2863 |  2464 | 1940 | ⋯ | 0 | 5 | 0 | 0 | 1 | 0 | 0 | 15 | 0 |  8 |\n",
       "| TCGA-CV-5979-01A |  1416 |  0 | 1383 |  594 |  517 |  160 | 6088 | 5182 |  3640 | 1324 | ⋯ | 0 | 0 | 0 | 0 | 0 | 0 | 0 |  8 | 0 | 17 |\n",
       "| TCGA-CQ-7069-01A |   728 |  0 | 1603 |  255 |  165 |  200 | 1027 | 1372 |   796 | 1018 | ⋯ | 0 | 0 | 0 | 1 | 0 | 0 | 0 |  6 | 0 | 10 |\n",
       "| TCGA-CN-4733-01A |   727 |  1 | 1151 |  481 |  463 |  934 | 6624 | 3854 |  2812 | 1833 | ⋯ | 0 | 0 | 0 | 0 | 7 | 0 | 0 |  9 | 0 | 10 |\n",
       "| TCGA-CR-7390-01A |  1995 |  1 | 1561 |  730 |  594 |  382 | 1708 | 2618 | 24128 | 2214 | ⋯ | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 15 | 0 | 32 |\n",
       "| TCGA-CV-A45X-01A |  1795 |  1 | 1913 |  977 |  516 |  211 | 1407 | 1556 |  2578 | 1250 | ⋯ | 0 | 5 | 0 | 3 | 0 | 0 | 0 |  9 | 0 | 14 |\n",
       "| TCGA-IQ-A6SH-01A |  1428 |  0 | 2404 |  393 |  334 |  166 | 6937 | 3944 |  7729 | 1394 | ⋯ | 0 | 3 | 0 | 0 | 3 | 1 | 0 |  9 | 0 | 44 |\n",
       "| TCGA-CV-6962-11A | 11809 |  4 | 1623 |  981 |  299 |  281 | 9783 | 1691 |  2135 | 1369 | ⋯ | 0 | 2 | 0 | 0 | 2 | 0 | 0 |  8 | 0 | 41 |\n",
       "| TCGA-CV-6960-11A |  3340 |  0 | 1388 |  608 |  206 |  304 | 6363 | 1242 |  2100 | 1369 | ⋯ | 0 | 1 | 0 | 2 | 1 | 0 | 0 | 12 | 0 | 19 |\n",
       "| TCGA-CV-A464-01A |   929 |  2 | 2332 |  472 |  386 |  331 | 7799 | 3028 |  2494 | 1711 | ⋯ | 0 | 3 | 1 | 2 | 3 | 0 | 1 |  1 | 0 | 46 |\n",
       "| TCGA-C9-A47Z-01A |  1707 |  0 | 1926 |  410 |  210 |  134 | 1264 | 1356 |  3710 | 1671 | ⋯ | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 35 | 0 | 14 |\n",
       "| TCGA-CN-6010-01A |  2218 |  0 | 1574 |  852 |  729 |  550 | 5558 | 2921 |  8749 | 1596 | ⋯ | 0 | 2 | 0 | 0 | 2 | 0 | 0 | 17 | 0 | 54 |\n",
       "| TCGA-WA-A7GZ-11A |  2537 | 41 | 1171 |  557 |  127 |  165 | 4651 |  647 |  3029 |  848 | ⋯ | 0 | 1 | 0 | 0 | 2 | 0 | 0 | 16 | 0 | 38 |\n",
       "| TCGA-CV-7235-01A |   492 |  0 |  976 |  376 |  363 |  488 | 5178 | 2138 | 20007 | 4131 | ⋯ | 0 | 2 | 2 | 1 | 0 | 0 | 0 |  8 | 0 | 60 |\n",
       "| TCGA-CX-7086-01A |  2741 |  0 | 1952 | 1003 | 1103 |  214 | 1809 | 2639 | 13623 | 2530 | ⋯ | 2 | 2 | 0 | 1 | 0 | 1 | 0 | 11 | 0 | 77 |\n",
       "| TCGA-CV-6935-11A |  8492 |  3 | 1578 |  818 |  281 |  419 | 7368 | 1355 |  2276 | 1583 | ⋯ | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 12 | 0 | 19 |\n",
       "| TCGA-P3-A6SW-01A |   770 |  1 | 1569 |  620 |  591 |  462 | 2082 | 1603 | 31675 | 1473 | ⋯ | 0 | 0 | 2 | 1 | 1 | 0 | 0 |  0 | 1 | 22 |\n",
       "| TCGA-HD-A6HZ-01A |   923 |  0 | 1183 |  607 |  344 |  925 | 2482 | 1769 |  3949 |  899 | ⋯ | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 11 | 1 | 40 |\n",
       "\n"
      ],
      "text/plain": [
       "                 TSPAN6 TNMD DPM1 SCYL3 C1orf112 FGR  CFH   FUCA2 GCLC  NFYA ⋯\n",
       "TCGA-BB-4224-01A  2237   2   1606 1063  1208      256   177 2371   2741 2515 ⋯\n",
       "TCGA-H7-7774-01A  2740   0   1691  803   317      330  5472 2316   8370  816 ⋯\n",
       "TCGA-CV-6943-01A  2686   0   1649  917   402     1535 15358 3490   4671 2080 ⋯\n",
       "TCGA-CN-5374-01A  2086   1   2333 1288  1105      639  5565 2065   2902 1777 ⋯\n",
       "TCGA-CQ-6227-01A 10167   9   3021  537   459      362  6963 4883   3140 2448 ⋯\n",
       "TCGA-CV-6959-01A  1154   6   2766  527   747      906 12856 6120   7448 3527 ⋯\n",
       "TCGA-F7-A61V-01A  1978   1   1762  482   331      147   793 2364   2827 1159 ⋯\n",
       "TCGA-CV-7413-01A  1930   1   1668  671   476      477  3669 3366   2324 1459 ⋯\n",
       "TCGA-CV-7247-01A  1066   1   1760  600   874      204  2791 1837   9779 1916 ⋯\n",
       "TCGA-CR-5249-01A  2538   0   1268 1066   950      924  5289 2584   2971 2572 ⋯\n",
       "TCGA-CQ-5331-01A  1465   0   2612 1027   766     1084 14982 5098   7356 4672 ⋯\n",
       "TCGA-BB-8601-01A  1630   1   1227  764   687       42   357 1270  19713 1255 ⋯\n",
       "TCGA-CV-A45W-01A  2215   0   1139  526   464     1024  1911 1741   8343 1061 ⋯\n",
       "TCGA-CQ-7063-01A   724   0   1220  461   235      668  4934 1323   1859 1229 ⋯\n",
       "TCGA-CN-5373-01A   718   0   1162  577   232      475  6444 2164   2870 1650 ⋯\n",
       "TCGA-CV-A45T-01A  2120   3   2252  614   340      700  4178 1998   1845 1197 ⋯\n",
       "TCGA-HD-A4C1-01A  1273   2   1793  646   461      238  4564 1802   2617 1129 ⋯\n",
       "TCGA-CV-7438-11A  4370   3   2064  648   367      444  3991 1808   3503 1599 ⋯\n",
       "TCGA-CV-5444-01A  1011   0   1488  627   366      607  5459 1695   1224 1192 ⋯\n",
       "TCGA-BA-5556-01A  1646   1   2146  763   538      967  9401 2521   3916 2173 ⋯\n",
       "TCGA-P3-A6SX-01A  1421   0   2413  794   986       76   563 2652   1788 1105 ⋯\n",
       "TCGA-CV-7242-11A  9952   9   2403  832   437     1000  6336 1563   4157 1589 ⋯\n",
       "TCGA-DQ-7592-01A  2923   0   2507  794   650      484  9116 3996   4762 3113 ⋯\n",
       "TCGA-CV-6937-01A  1232   2   1212  503   210      286   324 1607    866 1250 ⋯\n",
       "TCGA-QK-A8ZB-01A  2332   0   3280  642   507      491  5042 3292   2676 2995 ⋯\n",
       "TCGA-CV-7432-01A  2032   0   2069  434  1081      105  3398 3988   4089 2119 ⋯\n",
       "TCGA-CV-7089-01A  3005   0   2056  601   504      392  3379 3651   2524 1731 ⋯\n",
       "TCGA-CV-6939-11A  1612  53    729  488    45      155 10545 1223   1011  492 ⋯\n",
       "TCGA-BA-4075-01A  2950   1   5510  355   710      306  2114 2328   2450 2342 ⋯\n",
       "TCGA-T3-A92M-01A  1679   0   2430  624   759      379  2443 2379   1900 1833 ⋯\n",
       "⋮                ⋮      ⋮    ⋮    ⋮     ⋮        ⋮    ⋮     ⋮     ⋮     ⋮    ⋱\n",
       "TCGA-CV-7430-01A  3632   0   2857  362   389      136  606  3344  18448 1312 ⋯\n",
       "TCGA-D6-A74Q-01A  2368   0   3792  765   541      307 1291  4462   2878  985 ⋯\n",
       "TCGA-CV-7255-01A  5443   0   3542  884   979      135 5880  5834   2829 4707 ⋯\n",
       "TCGA-CQ-6223-01A  1406   1   1875  623   453      555 3190  2858   4875 1946 ⋯\n",
       "TCGA-CV-A460-01A  1049   0   2070  895   853      985 3735  1697   7706 2500 ⋯\n",
       "TCGA-CV-7261-01A  2048   2   1007  750   487      493 1735  2226  13697 1659 ⋯\n",
       "TCGA-CN-4736-01A   980  35   2072  613   287     2004 6050  3235  15570 1748 ⋯\n",
       "TCGA-CR-7404-01A  2646  18   2293 1259  1067     1147 6266  3687   8930 3086 ⋯\n",
       "TCGA-UF-A719-01A  5193   0   1751 1275  1325      203  352  3428  27455 2397 ⋯\n",
       "TCGA-CV-7236-01A  2366   0   1862  392   367      429 5933  2311   4241 3022 ⋯\n",
       "TCGA-CV-6951-01A  3280   1   1973  904   300      111  736  1844  15010 1314 ⋯\n",
       "TCGA-CN-4728-01A  1136   1   1739  668   347     2618 5170  2296   2764 1537 ⋯\n",
       "TCGA-CV-7090-01A  1050   3   1520  464   406      698 2617  2863   2464 1940 ⋯\n",
       "TCGA-CV-5979-01A  1416   0   1383  594   517      160 6088  5182   3640 1324 ⋯\n",
       "TCGA-CQ-7069-01A   728   0   1603  255   165      200 1027  1372    796 1018 ⋯\n",
       "TCGA-CN-4733-01A   727   1   1151  481   463      934 6624  3854   2812 1833 ⋯\n",
       "TCGA-CR-7390-01A  1995   1   1561  730   594      382 1708  2618  24128 2214 ⋯\n",
       "TCGA-CV-A45X-01A  1795   1   1913  977   516      211 1407  1556   2578 1250 ⋯\n",
       "TCGA-IQ-A6SH-01A  1428   0   2404  393   334      166 6937  3944   7729 1394 ⋯\n",
       "TCGA-CV-6962-11A 11809   4   1623  981   299      281 9783  1691   2135 1369 ⋯\n",
       "TCGA-CV-6960-11A  3340   0   1388  608   206      304 6363  1242   2100 1369 ⋯\n",
       "TCGA-CV-A464-01A   929   2   2332  472   386      331 7799  3028   2494 1711 ⋯\n",
       "TCGA-C9-A47Z-01A  1707   0   1926  410   210      134 1264  1356   3710 1671 ⋯\n",
       "TCGA-CN-6010-01A  2218   0   1574  852   729      550 5558  2921   8749 1596 ⋯\n",
       "TCGA-WA-A7GZ-11A  2537  41   1171  557   127      165 4651   647   3029  848 ⋯\n",
       "TCGA-CV-7235-01A   492   0    976  376   363      488 5178  2138  20007 4131 ⋯\n",
       "TCGA-CX-7086-01A  2741   0   1952 1003  1103      214 1809  2639  13623 2530 ⋯\n",
       "TCGA-CV-6935-11A  8492   3   1578  818   281      419 7368  1355   2276 1583 ⋯\n",
       "TCGA-P3-A6SW-01A   770   1   1569  620   591      462 2082  1603  31675 1473 ⋯\n",
       "TCGA-HD-A6HZ-01A   923   0   1183  607   344      925 2482  1769   3949  899 ⋯\n",
       "                 LINC00550 LINC01394 LINC00602 MIR1291 LINC00891 PAUPAR\n",
       "TCGA-BB-4224-01A 6         7         0          2      0         6     \n",
       "TCGA-H7-7774-01A 0         1         0          0      2         0     \n",
       "TCGA-CV-6943-01A 0         4         0          2      4         1     \n",
       "TCGA-CN-5374-01A 0         0         1          0      3         0     \n",
       "TCGA-CQ-6227-01A 1         3         0          0      2         0     \n",
       "TCGA-CV-6959-01A 0         1         0          1      3         1     \n",
       "TCGA-F7-A61V-01A 0         0         0          1      1         0     \n",
       "TCGA-CV-7413-01A 0         3         0          0      1         0     \n",
       "TCGA-CV-7247-01A 0         0         0          0      1         0     \n",
       "TCGA-CR-5249-01A 0         0         0          4      6         0     \n",
       "TCGA-CQ-5331-01A 0         1         1          2      1         0     \n",
       "TCGA-BB-8601-01A 1         0         0          3      0         0     \n",
       "TCGA-CV-A45W-01A 1         2         1          3      4         0     \n",
       "TCGA-CQ-7063-01A 0         0         0          1      1         0     \n",
       "TCGA-CN-5373-01A 0         0         0          1      1         0     \n",
       "TCGA-CV-A45T-01A 0         4         0          0      1         0     \n",
       "TCGA-HD-A4C1-01A 0         1         0          2      0         0     \n",
       "TCGA-CV-7438-11A 0         0         0          0      0         0     \n",
       "TCGA-CV-5444-01A 0         6         0          0      1         0     \n",
       "TCGA-BA-5556-01A 0         1         0          1      1         0     \n",
       "TCGA-P3-A6SX-01A 0         0         0          0      0         0     \n",
       "TCGA-CV-7242-11A 0         0         0          6      0         0     \n",
       "TCGA-DQ-7592-01A 0         5         1          0      1         0     \n",
       "TCGA-CV-6937-01A 0         2         0          1      0         0     \n",
       "TCGA-QK-A8ZB-01A 0         9         0         11      3         0     \n",
       "TCGA-CV-7432-01A 0         1         0          1      0         0     \n",
       "TCGA-CV-7089-01A 0         0         0          2      0         0     \n",
       "TCGA-CV-6939-11A 0         3         0          0      3         1     \n",
       "TCGA-BA-4075-01A 0         3         1          1      0         0     \n",
       "TCGA-T3-A92M-01A 0         8         0          3      1         0     \n",
       "⋮                ⋮         ⋮         ⋮         ⋮       ⋮         ⋮     \n",
       "TCGA-CV-7430-01A 0         0         0         3       0         0     \n",
       "TCGA-D6-A74Q-01A 0         3         0         1       6         5     \n",
       "TCGA-CV-7255-01A 0         1         0         0       0         0     \n",
       "TCGA-CQ-6223-01A 0         1         0         1       0         0     \n",
       "TCGA-CV-A460-01A 0         6         0         2       4         0     \n",
       "TCGA-CV-7261-01A 0         0         0         0       1         0     \n",
       "TCGA-CN-4736-01A 0         1         0         1       2         0     \n",
       "TCGA-CR-7404-01A 0         4         0         5       2         0     \n",
       "TCGA-UF-A719-01A 0         2         0         1       1         0     \n",
       "TCGA-CV-7236-01A 0         1         1         0       1         0     \n",
       "TCGA-CV-6951-01A 0         1         0         0       0         0     \n",
       "TCGA-CN-4728-01A 0         3         1         1       5         0     \n",
       "TCGA-CV-7090-01A 0         5         0         0       1         0     \n",
       "TCGA-CV-5979-01A 0         0         0         0       0         0     \n",
       "TCGA-CQ-7069-01A 0         0         0         1       0         0     \n",
       "TCGA-CN-4733-01A 0         0         0         0       7         0     \n",
       "TCGA-CR-7390-01A 0         1         0         1       0         0     \n",
       "TCGA-CV-A45X-01A 0         5         0         3       0         0     \n",
       "TCGA-IQ-A6SH-01A 0         3         0         0       3         1     \n",
       "TCGA-CV-6962-11A 0         2         0         0       2         0     \n",
       "TCGA-CV-6960-11A 0         1         0         2       1         0     \n",
       "TCGA-CV-A464-01A 0         3         1         2       3         0     \n",
       "TCGA-C9-A47Z-01A 0         0         0         4       0         0     \n",
       "TCGA-CN-6010-01A 0         2         0         0       2         0     \n",
       "TCGA-WA-A7GZ-11A 0         1         0         0       2         0     \n",
       "TCGA-CV-7235-01A 0         2         2         1       0         0     \n",
       "TCGA-CX-7086-01A 2         2         0         1       0         1     \n",
       "TCGA-CV-6935-11A 0         1         0         1       0         0     \n",
       "TCGA-P3-A6SW-01A 0         0         2         1       1         0     \n",
       "TCGA-HD-A6HZ-01A 0         1         0         0       1         0     \n",
       "                 GIMAP1-GIMAP5 LINC02246 HERC2P7 LINC01144\n",
       "TCGA-BB-4224-01A 0             16        0       144      \n",
       "TCGA-H7-7774-01A 0              6        0        23      \n",
       "TCGA-CV-6943-01A 0             38        0        18      \n",
       "TCGA-CN-5374-01A 0              4        0        31      \n",
       "TCGA-CQ-6227-01A 0             15        0        24      \n",
       "TCGA-CV-6959-01A 0             19        1        15      \n",
       "TCGA-F7-A61V-01A 0             15        0        20      \n",
       "TCGA-CV-7413-01A 0             19        1        23      \n",
       "TCGA-CV-7247-01A 0             17        1        43      \n",
       "TCGA-CR-5249-01A 0             17        1        27      \n",
       "TCGA-CQ-5331-01A 0             18        1        58      \n",
       "TCGA-BB-8601-01A 0              6        0        40      \n",
       "TCGA-CV-A45W-01A 0              0        0        43      \n",
       "TCGA-CQ-7063-01A 0              6        0        10      \n",
       "TCGA-CN-5373-01A 0             10        0         8      \n",
       "TCGA-CV-A45T-01A 0              3        0        25      \n",
       "TCGA-HD-A4C1-01A 0             14        0         2      \n",
       "TCGA-CV-7438-11A 0              9        0        32      \n",
       "TCGA-CV-5444-01A 0              8        0        36      \n",
       "TCGA-BA-5556-01A 0             24        0        13      \n",
       "TCGA-P3-A6SX-01A 0             17        0        19      \n",
       "TCGA-CV-7242-11A 0              7        0        12      \n",
       "TCGA-DQ-7592-01A 0             23        1        30      \n",
       "TCGA-CV-6937-01A 0              3        0       111      \n",
       "TCGA-QK-A8ZB-01A 0              1        0        24      \n",
       "TCGA-CV-7432-01A 0             13        0         4      \n",
       "TCGA-CV-7089-01A 0             18        0        15      \n",
       "TCGA-CV-6939-11A 0              7        0        68      \n",
       "TCGA-BA-4075-01A 0             20        0        10      \n",
       "TCGA-T3-A92M-01A 0             12        0       113      \n",
       "⋮                ⋮             ⋮         ⋮       ⋮        \n",
       "TCGA-CV-7430-01A 0             35        0        4       \n",
       "TCGA-D6-A74Q-01A 0             18        0       26       \n",
       "TCGA-CV-7255-01A 0             21        0       19       \n",
       "TCGA-CQ-6223-01A 0             17        0       50       \n",
       "TCGA-CV-A460-01A 0             10        0       25       \n",
       "TCGA-CV-7261-01A 0             11        1       21       \n",
       "TCGA-CN-4736-01A 0             12        1       20       \n",
       "TCGA-CR-7404-01A 0              6        0       99       \n",
       "TCGA-UF-A719-01A 0              3        0       81       \n",
       "TCGA-CV-7236-01A 0             32        0       22       \n",
       "TCGA-CV-6951-01A 0             19        0       44       \n",
       "TCGA-CN-4728-01A 0             10        1       12       \n",
       "TCGA-CV-7090-01A 0             15        0        8       \n",
       "TCGA-CV-5979-01A 0              8        0       17       \n",
       "TCGA-CQ-7069-01A 0              6        0       10       \n",
       "TCGA-CN-4733-01A 0              9        0       10       \n",
       "TCGA-CR-7390-01A 0             15        0       32       \n",
       "TCGA-CV-A45X-01A 0              9        0       14       \n",
       "TCGA-IQ-A6SH-01A 0              9        0       44       \n",
       "TCGA-CV-6962-11A 0              8        0       41       \n",
       "TCGA-CV-6960-11A 0             12        0       19       \n",
       "TCGA-CV-A464-01A 1              1        0       46       \n",
       "TCGA-C9-A47Z-01A 0             35        0       14       \n",
       "TCGA-CN-6010-01A 0             17        0       54       \n",
       "TCGA-WA-A7GZ-11A 0             16        0       38       \n",
       "TCGA-CV-7235-01A 0              8        0       60       \n",
       "TCGA-CX-7086-01A 0             11        0       77       \n",
       "TCGA-CV-6935-11A 0             12        0       19       \n",
       "TCGA-P3-A6SW-01A 0              0        1       22       \n",
       "TCGA-HD-A6HZ-01A 0             11        1       40       "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "df_TCGA"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 36,
   "id": "46553142",
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<table class=\"dataframe\">\n",
       "<caption>A data.frame: 4484 × 843</caption>\n",
       "<thead>\n",
       "\t<tr><th></th><th scope=col>WDR66</th><th scope=col>CST3</th><th scope=col>ACTN2</th><th scope=col>CPEB4</th><th scope=col>TMEM176B</th><th scope=col>COL6A2</th><th scope=col>BAG1</th><th scope=col>PELI1</th><th scope=col>COL3A1</th><th scope=col>SIGLEC17P</th><th scope=col>⋯</th><th scope=col>GLUL</th><th scope=col>LMO7</th><th scope=col>ATCAY</th><th scope=col>MCTP1</th><th scope=col>SERPINB5</th><th scope=col>ADRBK2</th><th scope=col>CD84</th><th scope=col>FAM105A</th><th scope=col>ZEB2</th><th scope=col>HLA-DQA2</th></tr>\n",
       "\t<tr><th></th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>⋯</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th></tr>\n",
       "</thead>\n",
       "<tbody>\n",
       "\t<tr><th scope=row>HN28_P15_D06_S330_comb</th><td> 0.0000000</td><td> 338.23758</td><td>0</td><td>30.3704590</td><td>  0.000000</td><td>  37.35117</td><td> 0.0000000</td><td>  0.000000</td><td>1.133014e+03</td><td>0</td><td>⋯</td><td>  50.4691800</td><td>  0.000000</td><td> 1.9999634</td><td>0</td><td>  0.000000</td><td> 0.35999998</td><td>0.8199962</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN28_P6_G05_S173_comb</th><td> 0.0000000</td><td> 456.30435</td><td>0</td><td>26.7896520</td><td>  0.000000</td><td>  76.78827</td><td> 0.0000000</td><td>  0.000000</td><td>6.960726e+01</td><td>0</td><td>⋯</td><td> 287.2902000</td><td>  0.000000</td><td> 2.7299786</td><td>0</td><td>  0.000000</td><td> 1.23998420</td><td>0.0000000</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
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       "\t<tr><th scope=row>HNSCC26_P24_H05_S377_comb</th><td> 0.0000000</td><td> 236.66823</td><td>0</td><td>26.2102970</td><td>  0.000000</td><td>   0.00000</td><td> 0.0000000</td><td>197.364930</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td>   0.8599691</td><td>  0.000000</td><td> 4.1000470</td><td>0</td><td> 96.693474</td><td> 0.37000075</td><td>2.4899700</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
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       "\t<tr><th scope=row>HN25_P24_B02_S110_comb</th><td>21.6191800</td><td> 926.94990</td><td>0</td><td> 9.2300170</td><td>  0.000000</td><td>   0.00000</td><td>20.9405750</td><td> 23.740936</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td>   0.0000000</td><td>  0.000000</td><td> 0.5400010</td><td>0</td><td>378.084800</td><td> 0.21000095</td><td>0.0000000</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
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       "\t<tr><th scope=row>HN28_P15_G06_S366_comb</th><td> 0.0000000</td><td> 362.30164</td><td>0</td><td> 0.0000000</td><td>  0.000000</td><td>  87.00775</td><td> 0.9899895</td><td>  0.000000</td><td>1.391376e+03</td><td>0</td><td>⋯</td><td> 455.4325000</td><td>  0.000000</td><td> 1.6399914</td><td>0</td><td>  0.000000</td><td> 0.00000000</td><td>0.9699732</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P6_B06_S18_comb</th><td> 0.0000000</td><td>   0.00000</td><td>0</td><td> 0.0000000</td><td>  0.000000</td><td>  27.09951</td><td> 0.9099917</td><td>  0.000000</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td>   0.0000000</td><td>  0.000000</td><td> 4.4600244</td><td>0</td><td>  0.000000</td><td> 0.73997027</td><td>0.0000000</td><td> 0.0000000</td><td>542.5756000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN25_P5_C05_S29_comb</th><td> 0.0000000</td><td>2177.89550</td><td>0</td><td>22.7092800</td><td> 29.119827</td><td> 185.43271</td><td> 0.0000000</td><td> 64.990090</td><td>1.247517e+04</td><td>0</td><td>⋯</td><td> 142.2003800</td><td>  0.000000</td><td> 1.4199790</td><td>0</td><td>  0.000000</td><td> 0.48000205</td><td>1.8299994</td><td>39.8191380</td><td>  0.8800109</td><td>0.000000</td></tr>\n",
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       "\t<tr><th scope=row>HN26_P5_E06_S54_comb</th><td> 0.0000000</td><td> 226.58717</td><td>0</td><td> 0.4900023</td><td>  0.000000</td><td>   0.00000</td><td>36.4088500</td><td> 91.050180</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td> 542.3459000</td><td> 28.280243</td><td> 1.4500190</td><td>0</td><td> 93.610620</td><td> 0.52999680</td><td>0.2999976</td><td> 0.0000000</td><td>  0.0000000</td><td>2.070036</td></tr>\n",
       "\t<tr><th scope=row>HN26_P26_H05_S377_comb</th><td> 0.0000000</td><td> 147.83005</td><td>0</td><td> 0.5200021</td><td>  5.350014</td><td>  11.68053</td><td>48.7504540</td><td> 77.671020</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td>  98.4907400</td><td>  2.780019</td><td> 1.5999614</td><td>0</td><td>138.779100</td><td> 0.00000000</td><td>0.6900011</td><td> 0.0000000</td><td>  0.0000000</td><td>5.810029</td></tr>\n",
       "\t<tr><th scope=row>HNSCC26_P24_F12_S360_comb</th><td> 0.0000000</td><td> 115.43778</td><td>0</td><td> 0.0000000</td><td>  0.000000</td><td>   0.00000</td><td> 0.5999981</td><td>  0.000000</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td> 195.4762900</td><td>  0.000000</td><td> 1.0599893</td><td>0</td><td>  0.000000</td><td> 0.29000014</td><td>0.8800109</td><td> 0.2900001</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC26_P24_F03_S351_comb</th><td> 0.0000000</td><td> 197.72458</td><td>0</td><td> 0.0000000</td><td>  0.000000</td><td>   0.00000</td><td> 0.0000000</td><td>109.919970</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td> 220.4369200</td><td>  0.000000</td><td> 3.3800175</td><td>0</td><td>384.923130</td><td> 0.75002490</td><td>1.5199943</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P6_D08_S44_comb</th><td> 0.0000000</td><td>  96.76745</td><td>0</td><td>55.1515730</td><td>  0.000000</td><td>   0.00000</td><td>37.7201960</td><td>204.335660</td><td>1.899996e-01</td><td>0</td><td>⋯</td><td>   0.0000000</td><td>117.462420</td><td> 3.4399707</td><td>0</td><td>  0.000000</td><td> 0.11999796</td><td>1.0700366</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN25_P5_E12_S60_comb</th><td> 0.0000000</td><td>1086.37680</td><td>0</td><td>21.8899100</td><td>  0.000000</td><td> 120.21286</td><td> 0.0000000</td><td>  1.330017</td><td>1.082690e+02</td><td>0</td><td>⋯</td><td>  85.3610400</td><td>  0.000000</td><td> 3.9200077</td><td>0</td><td>  0.000000</td><td> 0.00000000</td><td>0.6200017</td><td> 0.0000000</td><td> 67.3982000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HNSCC26_P24_C01_S313_comb</th><td> 0.0000000</td><td>  57.51930</td><td>0</td><td> 3.5000055</td><td>  0.000000</td><td>   0.00000</td><td>12.7300370</td><td> 45.558205</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td> 161.6383500</td><td>  0.000000</td><td> 3.8299890</td><td>0</td><td>  2.500017</td><td> 0.00000000</td><td>0.3399987</td><td> 0.2999976</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN25_P5_F01_S61_comb</th><td> 0.0000000</td><td>1163.92790</td><td>0</td><td>27.9710520</td><td>  0.000000</td><td> 143.97241</td><td> 2.3299760</td><td>  0.000000</td><td>4.923079e+02</td><td>0</td><td>⋯</td><td> 232.4138200</td><td>  0.000000</td><td> 5.0499635</td><td>0</td><td>  0.000000</td><td> 0.00000000</td><td>0.0000000</td><td> 0.0000000</td><td> 87.5809800</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN26_P5_D12_S48_comb</th><td> 0.0000000</td><td>1195.92800</td><td>0</td><td>49.6614900</td><td>  0.000000</td><td> 420.72644</td><td> 0.0000000</td><td>  0.000000</td><td>6.908821e+02</td><td>0</td><td>⋯</td><td>   0.0000000</td><td>  0.000000</td><td> 4.1399794</td><td>0</td><td>  0.000000</td><td> 0.00000000</td><td>0.6699987</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN25_P25_C11_S323_comb</th><td> 0.0000000</td><td>4091.76200</td><td>0</td><td>52.7580260</td><td>  0.000000</td><td>  41.57958</td><td> 0.4099995</td><td>  0.000000</td><td>1.287688e+03</td><td>0</td><td>⋯</td><td> 221.4133100</td><td>  0.000000</td><td> 4.2700460</td><td>0</td><td>  0.000000</td><td>76.02762600</td><td>1.9499949</td><td> 0.0000000</td><td>254.8126200</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>HN25_P25_B12_S312_comb</th><td>38.6183200</td><td> 348.30096</td><td>0</td><td> 0.0000000</td><td>  0.000000</td><td>   0.00000</td><td> 0.0000000</td><td>  6.029951</td><td>0.000000e+00</td><td>0</td><td>⋯</td><td>   0.0000000</td><td>  0.000000</td><td> 0.2400020</td><td>0</td><td>219.623750</td><td> 0.09999795</td><td>0.2400020</td><td> 0.0000000</td><td>  0.0000000</td><td>0.000000</td></tr>\n",
       "\t<tr><th scope=row>⋮</th><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋱</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_A08_S104_comb</th><td> 98.22786</td><td> 744.73590</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td>18.6890470</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td>1196.346100</td><td> 9.299989</td><td>0.4400021</td><td> 29.880957</td><td> 926.88495</td><td> 0.2199986</td><td>0.5400010</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_E10_S154_comb</th><td> 84.82714</td><td>1044.26950</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td>80.8004800</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td>5139.898000</td><td>24.359285</td><td>1.8900106</td><td>121.309555</td><td>2180.62700</td><td> 0.1700023</td><td>1.3499819</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_E02_S146_comb</th><td> 24.34024</td><td> 279.78278</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td> 0.0000000</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td>2884.559600</td><td> 0.000000</td><td>0.0000000</td><td>  0.000000</td><td>2420.48440</td><td> 0.0000000</td><td>0.0000000</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_F10_S262_comb</th><td> 63.45191</td><td> 123.65112</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td> 0.0000000</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td>   0.000000</td><td> 0.000000</td><td>2.1900158</td><td>  0.000000</td><td> 113.54802</td><td> 0.4000034</td><td>0.6499968</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_D04_S136_comb</th><td>136.26372</td><td> 878.80804</td><td>0</td><td>23.281029</td><td>0</td><td> 0.000000</td><td> 3.6399655</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td>1967.727700</td><td> 0.000000</td><td>0.7000015</td><td>136.354980</td><td>2629.46200</td><td> 0.0000000</td><td>0.2199986</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_C06_S222_comb</th><td> 35.00858</td><td> 289.77332</td><td>0</td><td>18.950735</td><td>0</td><td> 0.000000</td><td>17.8407880</td><td> 94.309600</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 472.313750</td><td> 0.000000</td><td>2.5400230</td><td>  0.000000</td><td> 417.15863</td><td>48.3082500</td><td>0.0000000</td><td>0.4400021</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_C12_S228_comb</th><td> 34.80936</td><td> 124.84219</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td> 0.0000000</td><td> 55.350580</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 427.769650</td><td> 0.000000</td><td>2.3900328</td><td>  0.000000</td><td> 481.56150</td><td> 0.0000000</td><td>0.0000000</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_H04_S184_comb</th><td> 79.17875</td><td> 228.26581</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td>12.2206340</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 642.090400</td><td>34.539950</td><td>0.1999989</td><td> 13.729801</td><td> 705.46040</td><td> 0.0000000</td><td>0.1299988</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_C06_S126_comb</th><td> 62.65187</td><td> 730.99915</td><td>0</td><td> 8.150005</td><td>0</td><td> 0.000000</td><td>17.4308620</td><td> 39.160515</td><td>0.0000000</td><td>0</td><td>⋯</td><td>5796.399400</td><td>14.730647</td><td>0.0000000</td><td>  2.679958</td><td>2165.04270</td><td> 1.6399914</td><td>0.5600012</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_D01_S37_comb</th><td>252.43713</td><td> 122.98577</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td> 0.0000000</td><td> 42.470260</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 388.580720</td><td>31.910160</td><td>0.5400010</td><td>  0.000000</td><td>  56.91826</td><td> 0.0000000</td><td>0.5699973</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_D09_S45_comb</th><td>214.97612</td><td> 345.67804</td><td>0</td><td> 0.000000</td><td>0</td><td>39.430450</td><td> 0.0000000</td><td> 54.768845</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 279.843050</td><td>14.629716</td><td>1.4999692</td><td>  0.000000</td><td> 116.74879</td><td> 6.1600313</td><td>0.5200021</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_E06_S150_comb</th><td> 47.37014</td><td> 692.34110</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td> 0.3600000</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td>1820.380700</td><td> 5.510014</td><td>0.5900030</td><td> 26.669992</td><td>1429.87520</td><td> 0.0000000</td><td>0.1800031</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_H10_S286_comb</th><td>101.81176</td><td> 280.28537</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td>31.8492000</td><td> 83.320885</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 379.081360</td><td>21.520710</td><td>1.3100084</td><td>  4.640045</td><td> 235.62747</td><td> 9.2300170</td><td>1.2300161</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_A02_S98_comb</th><td> 63.31966</td><td> 321.88235</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td> 0.4900023</td><td> 11.070142</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 623.511960</td><td> 0.000000</td><td>1.5399742</td><td>  0.000000</td><td>1446.63940</td><td> 0.0000000</td><td>0.9099917</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_D01_S229_comb</th><td> 88.10998</td><td> 164.50543</td><td>0</td><td> 0.000000</td><td>0</td><td>12.610611</td><td> 0.6699987</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 183.491730</td><td> 1.430036</td><td>1.2999783</td><td>  0.000000</td><td> 348.69855</td><td> 0.8899701</td><td>0.8199962</td><td>0.7099965</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_G02_S266_comb</th><td>186.69658</td><td> 368.46814</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td>32.1490480</td><td>108.342800</td><td>0.5600012</td><td>0</td><td>⋯</td><td> 216.650910</td><td> 0.000000</td><td>3.8500385</td><td>  0.000000</td><td> 183.86763</td><td> 0.6699987</td><td>0.3700007</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_B04_S112_comb</th><td>259.34810</td><td> 905.76150</td><td>0</td><td>11.480089</td><td>0</td><td> 0.000000</td><td> 1.2399842</td><td>111.316180</td><td>0.0000000</td><td>0</td><td>⋯</td><td>2021.638700</td><td> 0.000000</td><td>1.5199943</td><td>  0.000000</td><td> 288.23962</td><td> 0.3200002</td><td>1.0599893</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_C09_S129_comb</th><td> 33.40015</td><td>1537.18300</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td> 9.3299780</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td>7199.722700</td><td>57.090103</td><td>1.0900049</td><td>  0.000000</td><td>2257.56500</td><td> 0.2699987</td><td>1.5599889</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_A12_S204_comb</th><td> 48.70974</td><td> 222.84532</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td>15.7701330</td><td>100.816440</td><td>0.0000000</td><td>0</td><td>⋯</td><td>   9.459977</td><td> 4.529953</td><td>2.5199604</td><td>  0.000000</td><td> 818.88495</td><td> 0.0000000</td><td>0.4199980</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_F06_S162_comb</th><td>145.57086</td><td> 962.75190</td><td>0</td><td> 1.330017</td><td>0</td><td> 0.000000</td><td>63.9884450</td><td>141.989530</td><td>0.0000000</td><td>0</td><td>⋯</td><td>6650.100000</td><td> 0.000000</td><td>1.4600235</td><td>  0.000000</td><td> 594.13540</td><td> 0.0000000</td><td>0.6499968</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_B10_S22_comb</th><td>186.75113</td><td> 253.65875</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td>15.6791950</td><td> 65.391400</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 810.197800</td><td> 4.499971</td><td>1.2300161</td><td>  0.000000</td><td> 156.13683</td><td> 0.0000000</td><td>1.1100091</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_B11_S215_comb</th><td> 94.36022</td><td> 483.98660</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td>28.8792400</td><td> 98.498260</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 455.142200</td><td>26.840689</td><td>2.4500368</td><td>  0.000000</td><td> 193.43556</td><td> 1.0299786</td><td>0.4199980</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_C08_S32_comb</th><td>350.46817</td><td> 342.97644</td><td>0</td><td> 0.000000</td><td>0</td><td> 7.720017</td><td>54.4508800</td><td>  1.999963</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 156.044720</td><td>36.508680</td><td>2.1799650</td><td>  0.000000</td><td> 524.16000</td><td> 0.0000000</td><td>1.3599777</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_H03_S183_comb</th><td> 93.05196</td><td>1242.96300</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td> 0.0000000</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td>3388.136500</td><td> 3.300035</td><td>0.0000000</td><td>  0.000000</td><td> 452.05734</td><td> 0.1199980</td><td>0.0000000</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_F09_S69_comb</th><td> 60.96954</td><td> 176.91365</td><td>0</td><td> 0.000000</td><td>0</td><td> 7.170000</td><td> 0.0000000</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 225.066990</td><td> 0.000000</td><td>1.5399742</td><td>  0.000000</td><td>  84.84686</td><td> 0.6100025</td><td>0.2799981</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_G12_S180_comb</th><td>127.37999</td><td> 902.90955</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td>10.1698450</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 222.136260</td><td> 0.000000</td><td>2.1599727</td><td>  0.000000</td><td> 689.66870</td><td> 0.4900023</td><td>1.5399742</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P13_C05_S221_comb</th><td>106.59225</td><td> 794.87897</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td> 0.0000000</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td> 657.548160</td><td> 0.000000</td><td>5.0300520</td><td>  0.000000</td><td>  85.36765</td><td> 1.0299786</td><td>0.5699973</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC17_P4_C12_S132_comb</th><td>270.20290</td><td> 605.67630</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td>30.1500000</td><td>  0.000000</td><td>0.0000000</td><td>0</td><td>⋯</td><td>2413.419000</td><td>36.460350</td><td>0.2199986</td><td>  0.000000</td><td>1068.43850</td><td> 0.1199980</td><td>0.1400024</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_H08_S92_comb</th><td> 32.99891</td><td> 272.60205</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td> 0.0000000</td><td>129.394330</td><td>0.0000000</td><td>0</td><td>⋯</td><td>   0.000000</td><td>13.999428</td><td>2.2700405</td><td>  0.000000</td><td>   0.00000</td><td> 0.5500000</td><td>0.5400010</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "\t<tr><th scope=row>HNSCC20_P3_G06_S78_comb</th><td>129.81042</td><td>  81.10941</td><td>0</td><td> 0.000000</td><td>0</td><td> 0.000000</td><td> 0.0000000</td><td>526.534850</td><td>0.0000000</td><td>0</td><td>⋯</td><td>  75.831070</td><td> 4.959998</td><td>0.0000000</td><td>  0.000000</td><td> 195.76134</td><td>17.8890720</td><td>0.3900025</td><td>0.0000000</td><td>0</td><td>0</td></tr>\n",
       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "A data.frame: 4484 × 843\n",
       "\\begin{tabular}{r|lllllllllllllllllllll}\n",
       "  & WDR66 & CST3 & ACTN2 & CPEB4 & TMEM176B & COL6A2 & BAG1 & PELI1 & COL3A1 & SIGLEC17P & ⋯ & GLUL & LMO7 & ATCAY & MCTP1 & SERPINB5 & ADRBK2 & CD84 & FAM105A & ZEB2 & HLA-DQA2\\\\\n",
       "  & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & ⋯ & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl>\\\\\n",
       "\\hline\n",
       "\tHN28\\_P15\\_D06\\_S330\\_comb &  0.0000000 &  338.23758 & 0 & 30.3704590 &   0.000000 &   37.35117 &  0.0000000 &   0.000000 & 1.133014e+03 & 0 & ⋯ &   50.4691800 &   0.000000 &  1.9999634 & 0 &   0.000000 &  0.35999998 & 0.8199962 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN28\\_P6\\_G05\\_S173\\_comb &  0.0000000 &  456.30435 & 0 & 26.7896520 &   0.000000 &   76.78827 &  0.0000000 &   0.000000 & 6.960726e+01 & 0 & ⋯ &  287.2902000 &   0.000000 &  2.7299786 & 0 &   0.000000 &  1.23998420 & 0.0000000 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN26\\_P14\\_D11\\_S239\\_comb &  0.0000000 &  240.87555 & 0 &  0.1199980 &   0.000000 &    0.00000 & 17.1302050 &  89.783410 & 0.000000e+00 & 0 & ⋯ &  153.9518100 &   0.000000 &  1.1000025 & 0 &  77.422220 &  0.08000252 & 0.6499968 &  0.0000000 &   0.0000000 & 1.070037\\\\\n",
       "\tHN26\\_P14\\_H05\\_S281\\_comb &  0.0000000 &  325.28128 & 0 &  0.0000000 &   0.000000 &   72.78102 &  0.5100024 &   2.110009 & 2.895213e+03 & 0 & ⋯ & 1514.4025000 &   0.000000 &  1.6199994 & 0 &   0.000000 &  0.21999861 & 0.9899895 &  0.0000000 &  96.3980600 & 0.000000\\\\\n",
       "\tHN26\\_P25\\_H09\\_S189\\_comb &  2.1799650 &  176.21533 & 0 &  0.0000000 & 157.049070 &   39.33119 & 76.3382600 &   4.290040 & 0.000000e+00 & 0 & ⋯ &  175.1856000 &   0.000000 &  1.7199792 & 0 & 394.733400 &  0.00000000 & 0.5999981 &  0.0000000 &   0.0000000 & 4.249981\\\\\n",
       "\tHN26\\_P14\\_H06\\_S282\\_comb &  0.0000000 &  330.83463 & 0 &  0.5699973 &  61.398808 &    0.00000 & 80.9201400 &   0.000000 & 0.000000e+00 & 0 & ⋯ &  306.4926500 &   0.000000 &  0.7099965 & 0 & 190.384640 &  0.00000000 & 0.7099965 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN25\\_P25\\_C04\\_S316\\_comb & 70.9707000 & 1289.21830 & 0 &  0.0000000 &   0.000000 & 1140.32680 &  1.6500003 &   0.000000 & 0.000000e+00 & 0 & ⋯ &    0.0000000 &   0.000000 & 10.1796340 & 0 &  16.039469 &  0.78996360 & 6.7499870 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN26\\_P25\\_A11\\_S107\\_comb &  0.0000000 &   13.30921 & 0 &  2.9600384 &   0.000000 &   56.29959 &  0.9499934 &   0.000000 & 6.500485e+02 & 0 & ⋯ &    5.8499690 &   0.000000 &  4.4099965 & 0 &   0.000000 & 36.55060600 & 1.0800163 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN26\\_P25\\_C09\\_S129\\_comb &  0.0000000 &  108.90191 & 0 &  0.0000000 &   0.000000 &    0.00000 & 52.1907500 &  78.073010 & 0.000000e+00 & 0 & ⋯ &  208.9151600 &   0.000000 &  1.5299800 & 0 & 127.541970 &  0.17000227 & 0.7000015 &  0.1899996 &   0.0000000 & 0.000000\\\\\n",
       "\tHNSCC26\\_P24\\_H05\\_S377\\_comb &  0.0000000 &  236.66823 & 0 & 26.2102970 &   0.000000 &    0.00000 &  0.0000000 & 197.364930 & 0.000000e+00 & 0 & ⋯ &    0.8599691 &   0.000000 &  4.1000470 & 0 &  96.693474 &  0.37000075 & 2.4899700 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN25\\_P5\\_E10\\_S58\\_comb &  0.0000000 & 1413.50130 & 0 & 11.7106060 &   0.000000 &   48.79119 & 52.0013660 &  92.930595 & 2.056865e+03 & 0 & ⋯ &  194.9215900 &   0.000000 &  1.6299912 & 0 &   1.580038 &  0.00000000 & 2.6299593 &  0.0000000 &  67.7692600 & 0.000000\\\\\n",
       "\tHN25\\_P24\\_B02\\_S110\\_comb & 21.6191800 &  926.94990 & 0 &  9.2300170 &   0.000000 &    0.00000 & 20.9405750 &  23.740936 & 0.000000e+00 & 0 & ⋯ &    0.0000000 &   0.000000 &  0.5400010 & 0 & 378.084800 &  0.21000095 & 0.0000000 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN25\\_P25\\_C01\\_S313\\_comb &  0.0000000 &    0.00000 & 0 & 34.7100750 &   0.000000 &    0.00000 &  0.0000000 & 569.404900 & 0.000000e+00 & 0 & ⋯ &    0.0000000 &   0.000000 &  3.8299890 & 0 &   0.000000 &  0.88997010 & 0.9499934 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN28\\_P15\\_G06\\_S366\\_comb &  0.0000000 &  362.30164 & 0 &  0.0000000 &   0.000000 &   87.00775 &  0.9899895 &   0.000000 & 1.391376e+03 & 0 & ⋯ &  455.4325000 &   0.000000 &  1.6399914 & 0 &   0.000000 &  0.00000000 & 0.9699732 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN26\\_P6\\_B06\\_S18\\_comb &  0.0000000 &    0.00000 & 0 &  0.0000000 &   0.000000 &   27.09951 &  0.9099917 &   0.000000 & 0.000000e+00 & 0 & ⋯ &    0.0000000 &   0.000000 &  4.4600244 & 0 &   0.000000 &  0.73997027 & 0.0000000 &  0.0000000 & 542.5756000 & 0.000000\\\\\n",
       "\tHN25\\_P5\\_C05\\_S29\\_comb &  0.0000000 & 2177.89550 & 0 & 22.7092800 &  29.119827 &  185.43271 &  0.0000000 &  64.990090 & 1.247517e+04 & 0 & ⋯ &  142.2003800 &   0.000000 &  1.4199790 & 0 &   0.000000 &  0.48000205 & 1.8299994 & 39.8191380 &   0.8800109 & 0.000000\\\\\n",
       "\tHN28\\_P6\\_D09\\_S141\\_comb &  0.0000000 &  550.87213 & 0 &  0.0000000 &   0.000000 &    0.00000 &  2.1000247 &   0.000000 & 1.450019e+00 & 0 & ⋯ & 1068.3636000 &   0.000000 &  5.9099580 & 0 &   0.000000 &  0.00000000 & 0.9600167 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN26\\_P5\\_H01\\_S85\\_comb &  0.6100025 &   54.54029 & 0 &  0.0000000 &   0.000000 &    0.00000 &  0.0000000 &  76.938790 & 0.000000e+00 & 0 & ⋯ &  167.5311100 &   0.000000 &  4.3199854 & 0 & 192.226470 &  0.26999870 & 1.4199790 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN26\\_P13\\_D07\\_S139\\_comb &  0.0000000 &  861.05990 & 0 &  0.0000000 &   0.000000 &  173.53712 &  0.0000000 &   0.000000 & 0.000000e+00 & 0 & ⋯ &    0.0000000 &   0.000000 &  4.5199850 & 0 &   0.000000 &  0.00000000 & 1.4799789 &  0.0000000 &  77.5070950 & 0.000000\\\\\n",
       "\tHN26\\_P5\\_E06\\_S54\\_comb &  0.0000000 &  226.58717 & 0 &  0.4900023 &   0.000000 &    0.00000 & 36.4088500 &  91.050180 & 0.000000e+00 & 0 & ⋯ &  542.3459000 &  28.280243 &  1.4500190 & 0 &  93.610620 &  0.52999680 & 0.2999976 &  0.0000000 &   0.0000000 & 2.070036\\\\\n",
       "\tHN26\\_P26\\_H05\\_S377\\_comb &  0.0000000 &  147.83005 & 0 &  0.5200021 &   5.350014 &   11.68053 & 48.7504540 &  77.671020 & 0.000000e+00 & 0 & ⋯ &   98.4907400 &   2.780019 &  1.5999614 & 0 & 138.779100 &  0.00000000 & 0.6900011 &  0.0000000 &   0.0000000 & 5.810029\\\\\n",
       "\tHNSCC26\\_P24\\_F12\\_S360\\_comb &  0.0000000 &  115.43778 & 0 &  0.0000000 &   0.000000 &    0.00000 &  0.5999981 &   0.000000 & 0.000000e+00 & 0 & ⋯ &  195.4762900 &   0.000000 &  1.0599893 & 0 &   0.000000 &  0.29000014 & 0.8800109 &  0.2900001 &   0.0000000 & 0.000000\\\\\n",
       "\tHNSCC26\\_P24\\_F03\\_S351\\_comb &  0.0000000 &  197.72458 & 0 &  0.0000000 &   0.000000 &    0.00000 &  0.0000000 & 109.919970 & 0.000000e+00 & 0 & ⋯ &  220.4369200 &   0.000000 &  3.3800175 & 0 & 384.923130 &  0.75002490 & 1.5199943 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN26\\_P6\\_D08\\_S44\\_comb &  0.0000000 &   96.76745 & 0 & 55.1515730 &   0.000000 &    0.00000 & 37.7201960 & 204.335660 & 1.899996e-01 & 0 & ⋯ &    0.0000000 & 117.462420 &  3.4399707 & 0 &   0.000000 &  0.11999796 & 1.0700366 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN25\\_P5\\_E12\\_S60\\_comb &  0.0000000 & 1086.37680 & 0 & 21.8899100 &   0.000000 &  120.21286 &  0.0000000 &   1.330017 & 1.082690e+02 & 0 & ⋯ &   85.3610400 &   0.000000 &  3.9200077 & 0 &   0.000000 &  0.00000000 & 0.6200017 &  0.0000000 &  67.3982000 & 0.000000\\\\\n",
       "\tHNSCC26\\_P24\\_C01\\_S313\\_comb &  0.0000000 &   57.51930 & 0 &  3.5000055 &   0.000000 &    0.00000 & 12.7300370 &  45.558205 & 0.000000e+00 & 0 & ⋯ &  161.6383500 &   0.000000 &  3.8299890 & 0 &   2.500017 &  0.00000000 & 0.3399987 &  0.2999976 &   0.0000000 & 0.000000\\\\\n",
       "\tHN25\\_P5\\_F01\\_S61\\_comb &  0.0000000 & 1163.92790 & 0 & 27.9710520 &   0.000000 &  143.97241 &  2.3299760 &   0.000000 & 4.923079e+02 & 0 & ⋯ &  232.4138200 &   0.000000 &  5.0499635 & 0 &   0.000000 &  0.00000000 & 0.0000000 &  0.0000000 &  87.5809800 & 0.000000\\\\\n",
       "\tHN26\\_P5\\_D12\\_S48\\_comb &  0.0000000 & 1195.92800 & 0 & 49.6614900 &   0.000000 &  420.72644 &  0.0000000 &   0.000000 & 6.908821e+02 & 0 & ⋯ &    0.0000000 &   0.000000 &  4.1399794 & 0 &   0.000000 &  0.00000000 & 0.6699987 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\tHN25\\_P25\\_C11\\_S323\\_comb &  0.0000000 & 4091.76200 & 0 & 52.7580260 &   0.000000 &   41.57958 &  0.4099995 &   0.000000 & 1.287688e+03 & 0 & ⋯ &  221.4133100 &   0.000000 &  4.2700460 & 0 &   0.000000 & 76.02762600 & 1.9499949 &  0.0000000 & 254.8126200 & 0.000000\\\\\n",
       "\tHN25\\_P25\\_B12\\_S312\\_comb & 38.6183200 &  348.30096 & 0 &  0.0000000 &   0.000000 &    0.00000 &  0.0000000 &   6.029951 & 0.000000e+00 & 0 & ⋯ &    0.0000000 &   0.000000 &  0.2400020 & 0 & 219.623750 &  0.09999795 & 0.2400020 &  0.0000000 &   0.0000000 & 0.000000\\\\\n",
       "\t⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋱ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮\\\\\n",
       "\tHNSCC17\\_P4\\_A08\\_S104\\_comb &  98.22786 &  744.73590 & 0 &  0.000000 & 0 &  0.000000 & 18.6890470 &   0.000000 & 0.0000000 & 0 & ⋯ & 1196.346100 &  9.299989 & 0.4400021 &  29.880957 &  926.88495 &  0.2199986 & 0.5400010 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_E10\\_S154\\_comb &  84.82714 & 1044.26950 & 0 &  0.000000 & 0 &  0.000000 & 80.8004800 &   0.000000 & 0.0000000 & 0 & ⋯ & 5139.898000 & 24.359285 & 1.8900106 & 121.309555 & 2180.62700 &  0.1700023 & 1.3499819 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_E02\\_S146\\_comb &  24.34024 &  279.78278 & 0 &  0.000000 & 0 &  0.000000 &  0.0000000 &   0.000000 & 0.0000000 & 0 & ⋯ & 2884.559600 &  0.000000 & 0.0000000 &   0.000000 & 2420.48440 &  0.0000000 & 0.0000000 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_F10\\_S262\\_comb &  63.45191 &  123.65112 & 0 &  0.000000 & 0 &  0.000000 &  0.0000000 &   0.000000 & 0.0000000 & 0 & ⋯ &    0.000000 &  0.000000 & 2.1900158 &   0.000000 &  113.54802 &  0.4000034 & 0.6499968 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_D04\\_S136\\_comb & 136.26372 &  878.80804 & 0 & 23.281029 & 0 &  0.000000 &  3.6399655 &   0.000000 & 0.0000000 & 0 & ⋯ & 1967.727700 &  0.000000 & 0.7000015 & 136.354980 & 2629.46200 &  0.0000000 & 0.2199986 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_C06\\_S222\\_comb &  35.00858 &  289.77332 & 0 & 18.950735 & 0 &  0.000000 & 17.8407880 &  94.309600 & 0.0000000 & 0 & ⋯ &  472.313750 &  0.000000 & 2.5400230 &   0.000000 &  417.15863 & 48.3082500 & 0.0000000 & 0.4400021 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_C12\\_S228\\_comb &  34.80936 &  124.84219 & 0 &  0.000000 & 0 &  0.000000 &  0.0000000 &  55.350580 & 0.0000000 & 0 & ⋯ &  427.769650 &  0.000000 & 2.3900328 &   0.000000 &  481.56150 &  0.0000000 & 0.0000000 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_H04\\_S184\\_comb &  79.17875 &  228.26581 & 0 &  0.000000 & 0 &  0.000000 & 12.2206340 &   0.000000 & 0.0000000 & 0 & ⋯ &  642.090400 & 34.539950 & 0.1999989 &  13.729801 &  705.46040 &  0.0000000 & 0.1299988 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_C06\\_S126\\_comb &  62.65187 &  730.99915 & 0 &  8.150005 & 0 &  0.000000 & 17.4308620 &  39.160515 & 0.0000000 & 0 & ⋯ & 5796.399400 & 14.730647 & 0.0000000 &   2.679958 & 2165.04270 &  1.6399914 & 0.5600012 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P3\\_D01\\_S37\\_comb & 252.43713 &  122.98577 & 0 &  0.000000 & 0 &  0.000000 &  0.0000000 &  42.470260 & 0.0000000 & 0 & ⋯ &  388.580720 & 31.910160 & 0.5400010 &   0.000000 &   56.91826 &  0.0000000 & 0.5699973 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P3\\_D09\\_S45\\_comb & 214.97612 &  345.67804 & 0 &  0.000000 & 0 & 39.430450 &  0.0000000 &  54.768845 & 0.0000000 & 0 & ⋯ &  279.843050 & 14.629716 & 1.4999692 &   0.000000 &  116.74879 &  6.1600313 & 0.5200021 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_E06\\_S150\\_comb &  47.37014 &  692.34110 & 0 &  0.000000 & 0 &  0.000000 &  0.3600000 &   0.000000 & 0.0000000 & 0 & ⋯ & 1820.380700 &  5.510014 & 0.5900030 &  26.669992 & 1429.87520 &  0.0000000 & 0.1800031 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_H10\\_S286\\_comb & 101.81176 &  280.28537 & 0 &  0.000000 & 0 &  0.000000 & 31.8492000 &  83.320885 & 0.0000000 & 0 & ⋯ &  379.081360 & 21.520710 & 1.3100084 &   4.640045 &  235.62747 &  9.2300170 & 1.2300161 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_A02\\_S98\\_comb &  63.31966 &  321.88235 & 0 &  0.000000 & 0 &  0.000000 &  0.4900023 &  11.070142 & 0.0000000 & 0 & ⋯ &  623.511960 &  0.000000 & 1.5399742 &   0.000000 & 1446.63940 &  0.0000000 & 0.9099917 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_D01\\_S229\\_comb &  88.10998 &  164.50543 & 0 &  0.000000 & 0 & 12.610611 &  0.6699987 &   0.000000 & 0.0000000 & 0 & ⋯ &  183.491730 &  1.430036 & 1.2999783 &   0.000000 &  348.69855 &  0.8899701 & 0.8199962 & 0.7099965 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_G02\\_S266\\_comb & 186.69658 &  368.46814 & 0 &  0.000000 & 0 &  0.000000 & 32.1490480 & 108.342800 & 0.5600012 & 0 & ⋯ &  216.650910 &  0.000000 & 3.8500385 &   0.000000 &  183.86763 &  0.6699987 & 0.3700007 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_B04\\_S112\\_comb & 259.34810 &  905.76150 & 0 & 11.480089 & 0 &  0.000000 &  1.2399842 & 111.316180 & 0.0000000 & 0 & ⋯ & 2021.638700 &  0.000000 & 1.5199943 &   0.000000 &  288.23962 &  0.3200002 & 1.0599893 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_C09\\_S129\\_comb &  33.40015 & 1537.18300 & 0 &  0.000000 & 0 &  0.000000 &  9.3299780 &   0.000000 & 0.0000000 & 0 & ⋯ & 7199.722700 & 57.090103 & 1.0900049 &   0.000000 & 2257.56500 &  0.2699987 & 1.5599889 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_A12\\_S204\\_comb &  48.70974 &  222.84532 & 0 &  0.000000 & 0 &  0.000000 & 15.7701330 & 100.816440 & 0.0000000 & 0 & ⋯ &    9.459977 &  4.529953 & 2.5199604 &   0.000000 &  818.88495 &  0.0000000 & 0.4199980 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_F06\\_S162\\_comb & 145.57086 &  962.75190 & 0 &  1.330017 & 0 &  0.000000 & 63.9884450 & 141.989530 & 0.0000000 & 0 & ⋯ & 6650.100000 &  0.000000 & 1.4600235 &   0.000000 &  594.13540 &  0.0000000 & 0.6499968 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P3\\_B10\\_S22\\_comb & 186.75113 &  253.65875 & 0 &  0.000000 & 0 &  0.000000 & 15.6791950 &  65.391400 & 0.0000000 & 0 & ⋯ &  810.197800 &  4.499971 & 1.2300161 &   0.000000 &  156.13683 &  0.0000000 & 1.1100091 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_B11\\_S215\\_comb &  94.36022 &  483.98660 & 0 &  0.000000 & 0 &  0.000000 & 28.8792400 &  98.498260 & 0.0000000 & 0 & ⋯ &  455.142200 & 26.840689 & 2.4500368 &   0.000000 &  193.43556 &  1.0299786 & 0.4199980 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P3\\_C08\\_S32\\_comb & 350.46817 &  342.97644 & 0 &  0.000000 & 0 &  7.720017 & 54.4508800 &   1.999963 & 0.0000000 & 0 & ⋯ &  156.044720 & 36.508680 & 2.1799650 &   0.000000 &  524.16000 &  0.0000000 & 1.3599777 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_H03\\_S183\\_comb &  93.05196 & 1242.96300 & 0 &  0.000000 & 0 &  0.000000 &  0.0000000 &   0.000000 & 0.0000000 & 0 & ⋯ & 3388.136500 &  3.300035 & 0.0000000 &   0.000000 &  452.05734 &  0.1199980 & 0.0000000 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P3\\_F09\\_S69\\_comb &  60.96954 &  176.91365 & 0 &  0.000000 & 0 &  7.170000 &  0.0000000 &   0.000000 & 0.0000000 & 0 & ⋯ &  225.066990 &  0.000000 & 1.5399742 &   0.000000 &   84.84686 &  0.6100025 & 0.2799981 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_G12\\_S180\\_comb & 127.37999 &  902.90955 & 0 &  0.000000 & 0 &  0.000000 & 10.1698450 &   0.000000 & 0.0000000 & 0 & ⋯ &  222.136260 &  0.000000 & 2.1599727 &   0.000000 &  689.66870 &  0.4900023 & 1.5399742 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P13\\_C05\\_S221\\_comb & 106.59225 &  794.87897 & 0 &  0.000000 & 0 &  0.000000 &  0.0000000 &   0.000000 & 0.0000000 & 0 & ⋯ &  657.548160 &  0.000000 & 5.0300520 &   0.000000 &   85.36765 &  1.0299786 & 0.5699973 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC17\\_P4\\_C12\\_S132\\_comb & 270.20290 &  605.67630 & 0 &  0.000000 & 0 &  0.000000 & 30.1500000 &   0.000000 & 0.0000000 & 0 & ⋯ & 2413.419000 & 36.460350 & 0.2199986 &   0.000000 & 1068.43850 &  0.1199980 & 0.1400024 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P3\\_H08\\_S92\\_comb &  32.99891 &  272.60205 & 0 &  0.000000 & 0 &  0.000000 &  0.0000000 & 129.394330 & 0.0000000 & 0 & ⋯ &    0.000000 & 13.999428 & 2.2700405 &   0.000000 &    0.00000 &  0.5500000 & 0.5400010 & 0.0000000 & 0 & 0\\\\\n",
       "\tHNSCC20\\_P3\\_G06\\_S78\\_comb & 129.81042 &   81.10941 & 0 &  0.000000 & 0 &  0.000000 &  0.0000000 & 526.534850 & 0.0000000 & 0 & ⋯ &   75.831070 &  4.959998 & 0.0000000 &   0.000000 &  195.76134 & 17.8890720 & 0.3900025 & 0.0000000 & 0 & 0\\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "A data.frame: 4484 × 843\n",
       "\n",
       "| <!--/--> | WDR66 &lt;dbl&gt; | CST3 &lt;dbl&gt; | ACTN2 &lt;dbl&gt; | CPEB4 &lt;dbl&gt; | TMEM176B &lt;dbl&gt; | COL6A2 &lt;dbl&gt; | BAG1 &lt;dbl&gt; | PELI1 &lt;dbl&gt; | COL3A1 &lt;dbl&gt; | SIGLEC17P &lt;dbl&gt; | ⋯ ⋯ | GLUL &lt;dbl&gt; | LMO7 &lt;dbl&gt; | ATCAY &lt;dbl&gt; | MCTP1 &lt;dbl&gt; | SERPINB5 &lt;dbl&gt; | ADRBK2 &lt;dbl&gt; | CD84 &lt;dbl&gt; | FAM105A &lt;dbl&gt; | ZEB2 &lt;dbl&gt; | HLA-DQA2 &lt;dbl&gt; |\n",
       "|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|\n",
       "| HN28_P15_D06_S330_comb |  0.0000000 |  338.23758 | 0 | 30.3704590 |   0.000000 |   37.35117 |  0.0000000 |   0.000000 | 1.133014e+03 | 0 | ⋯ |   50.4691800 |   0.000000 |  1.9999634 | 0 |   0.000000 |  0.35999998 | 0.8199962 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN28_P6_G05_S173_comb |  0.0000000 |  456.30435 | 0 | 26.7896520 |   0.000000 |   76.78827 |  0.0000000 |   0.000000 | 6.960726e+01 | 0 | ⋯ |  287.2902000 |   0.000000 |  2.7299786 | 0 |   0.000000 |  1.23998420 | 0.0000000 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN26_P14_D11_S239_comb |  0.0000000 |  240.87555 | 0 |  0.1199980 |   0.000000 |    0.00000 | 17.1302050 |  89.783410 | 0.000000e+00 | 0 | ⋯ |  153.9518100 |   0.000000 |  1.1000025 | 0 |  77.422220 |  0.08000252 | 0.6499968 |  0.0000000 |   0.0000000 | 1.070037 |\n",
       "| HN26_P14_H05_S281_comb |  0.0000000 |  325.28128 | 0 |  0.0000000 |   0.000000 |   72.78102 |  0.5100024 |   2.110009 | 2.895213e+03 | 0 | ⋯ | 1514.4025000 |   0.000000 |  1.6199994 | 0 |   0.000000 |  0.21999861 | 0.9899895 |  0.0000000 |  96.3980600 | 0.000000 |\n",
       "| HN26_P25_H09_S189_comb |  2.1799650 |  176.21533 | 0 |  0.0000000 | 157.049070 |   39.33119 | 76.3382600 |   4.290040 | 0.000000e+00 | 0 | ⋯ |  175.1856000 |   0.000000 |  1.7199792 | 0 | 394.733400 |  0.00000000 | 0.5999981 |  0.0000000 |   0.0000000 | 4.249981 |\n",
       "| HN26_P14_H06_S282_comb |  0.0000000 |  330.83463 | 0 |  0.5699973 |  61.398808 |    0.00000 | 80.9201400 |   0.000000 | 0.000000e+00 | 0 | ⋯ |  306.4926500 |   0.000000 |  0.7099965 | 0 | 190.384640 |  0.00000000 | 0.7099965 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN25_P25_C04_S316_comb | 70.9707000 | 1289.21830 | 0 |  0.0000000 |   0.000000 | 1140.32680 |  1.6500003 |   0.000000 | 0.000000e+00 | 0 | ⋯ |    0.0000000 |   0.000000 | 10.1796340 | 0 |  16.039469 |  0.78996360 | 6.7499870 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN26_P25_A11_S107_comb |  0.0000000 |   13.30921 | 0 |  2.9600384 |   0.000000 |   56.29959 |  0.9499934 |   0.000000 | 6.500485e+02 | 0 | ⋯ |    5.8499690 |   0.000000 |  4.4099965 | 0 |   0.000000 | 36.55060600 | 1.0800163 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN26_P25_C09_S129_comb |  0.0000000 |  108.90191 | 0 |  0.0000000 |   0.000000 |    0.00000 | 52.1907500 |  78.073010 | 0.000000e+00 | 0 | ⋯ |  208.9151600 |   0.000000 |  1.5299800 | 0 | 127.541970 |  0.17000227 | 0.7000015 |  0.1899996 |   0.0000000 | 0.000000 |\n",
       "| HNSCC26_P24_H05_S377_comb |  0.0000000 |  236.66823 | 0 | 26.2102970 |   0.000000 |    0.00000 |  0.0000000 | 197.364930 | 0.000000e+00 | 0 | ⋯ |    0.8599691 |   0.000000 |  4.1000470 | 0 |  96.693474 |  0.37000075 | 2.4899700 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN25_P5_E10_S58_comb |  0.0000000 | 1413.50130 | 0 | 11.7106060 |   0.000000 |   48.79119 | 52.0013660 |  92.930595 | 2.056865e+03 | 0 | ⋯ |  194.9215900 |   0.000000 |  1.6299912 | 0 |   1.580038 |  0.00000000 | 2.6299593 |  0.0000000 |  67.7692600 | 0.000000 |\n",
       "| HN25_P24_B02_S110_comb | 21.6191800 |  926.94990 | 0 |  9.2300170 |   0.000000 |    0.00000 | 20.9405750 |  23.740936 | 0.000000e+00 | 0 | ⋯ |    0.0000000 |   0.000000 |  0.5400010 | 0 | 378.084800 |  0.21000095 | 0.0000000 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN25_P25_C01_S313_comb |  0.0000000 |    0.00000 | 0 | 34.7100750 |   0.000000 |    0.00000 |  0.0000000 | 569.404900 | 0.000000e+00 | 0 | ⋯ |    0.0000000 |   0.000000 |  3.8299890 | 0 |   0.000000 |  0.88997010 | 0.9499934 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN28_P15_G06_S366_comb |  0.0000000 |  362.30164 | 0 |  0.0000000 |   0.000000 |   87.00775 |  0.9899895 |   0.000000 | 1.391376e+03 | 0 | ⋯ |  455.4325000 |   0.000000 |  1.6399914 | 0 |   0.000000 |  0.00000000 | 0.9699732 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN26_P6_B06_S18_comb |  0.0000000 |    0.00000 | 0 |  0.0000000 |   0.000000 |   27.09951 |  0.9099917 |   0.000000 | 0.000000e+00 | 0 | ⋯ |    0.0000000 |   0.000000 |  4.4600244 | 0 |   0.000000 |  0.73997027 | 0.0000000 |  0.0000000 | 542.5756000 | 0.000000 |\n",
       "| HN25_P5_C05_S29_comb |  0.0000000 | 2177.89550 | 0 | 22.7092800 |  29.119827 |  185.43271 |  0.0000000 |  64.990090 | 1.247517e+04 | 0 | ⋯ |  142.2003800 |   0.000000 |  1.4199790 | 0 |   0.000000 |  0.48000205 | 1.8299994 | 39.8191380 |   0.8800109 | 0.000000 |\n",
       "| HN28_P6_D09_S141_comb |  0.0000000 |  550.87213 | 0 |  0.0000000 |   0.000000 |    0.00000 |  2.1000247 |   0.000000 | 1.450019e+00 | 0 | ⋯ | 1068.3636000 |   0.000000 |  5.9099580 | 0 |   0.000000 |  0.00000000 | 0.9600167 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN26_P5_H01_S85_comb |  0.6100025 |   54.54029 | 0 |  0.0000000 |   0.000000 |    0.00000 |  0.0000000 |  76.938790 | 0.000000e+00 | 0 | ⋯ |  167.5311100 |   0.000000 |  4.3199854 | 0 | 192.226470 |  0.26999870 | 1.4199790 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN26_P13_D07_S139_comb |  0.0000000 |  861.05990 | 0 |  0.0000000 |   0.000000 |  173.53712 |  0.0000000 |   0.000000 | 0.000000e+00 | 0 | ⋯ |    0.0000000 |   0.000000 |  4.5199850 | 0 |   0.000000 |  0.00000000 | 1.4799789 |  0.0000000 |  77.5070950 | 0.000000 |\n",
       "| HN26_P5_E06_S54_comb |  0.0000000 |  226.58717 | 0 |  0.4900023 |   0.000000 |    0.00000 | 36.4088500 |  91.050180 | 0.000000e+00 | 0 | ⋯ |  542.3459000 |  28.280243 |  1.4500190 | 0 |  93.610620 |  0.52999680 | 0.2999976 |  0.0000000 |   0.0000000 | 2.070036 |\n",
       "| HN26_P26_H05_S377_comb |  0.0000000 |  147.83005 | 0 |  0.5200021 |   5.350014 |   11.68053 | 48.7504540 |  77.671020 | 0.000000e+00 | 0 | ⋯ |   98.4907400 |   2.780019 |  1.5999614 | 0 | 138.779100 |  0.00000000 | 0.6900011 |  0.0000000 |   0.0000000 | 5.810029 |\n",
       "| HNSCC26_P24_F12_S360_comb |  0.0000000 |  115.43778 | 0 |  0.0000000 |   0.000000 |    0.00000 |  0.5999981 |   0.000000 | 0.000000e+00 | 0 | ⋯ |  195.4762900 |   0.000000 |  1.0599893 | 0 |   0.000000 |  0.29000014 | 0.8800109 |  0.2900001 |   0.0000000 | 0.000000 |\n",
       "| HNSCC26_P24_F03_S351_comb |  0.0000000 |  197.72458 | 0 |  0.0000000 |   0.000000 |    0.00000 |  0.0000000 | 109.919970 | 0.000000e+00 | 0 | ⋯ |  220.4369200 |   0.000000 |  3.3800175 | 0 | 384.923130 |  0.75002490 | 1.5199943 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN26_P6_D08_S44_comb |  0.0000000 |   96.76745 | 0 | 55.1515730 |   0.000000 |    0.00000 | 37.7201960 | 204.335660 | 1.899996e-01 | 0 | ⋯ |    0.0000000 | 117.462420 |  3.4399707 | 0 |   0.000000 |  0.11999796 | 1.0700366 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN25_P5_E12_S60_comb |  0.0000000 | 1086.37680 | 0 | 21.8899100 |   0.000000 |  120.21286 |  0.0000000 |   1.330017 | 1.082690e+02 | 0 | ⋯ |   85.3610400 |   0.000000 |  3.9200077 | 0 |   0.000000 |  0.00000000 | 0.6200017 |  0.0000000 |  67.3982000 | 0.000000 |\n",
       "| HNSCC26_P24_C01_S313_comb |  0.0000000 |   57.51930 | 0 |  3.5000055 |   0.000000 |    0.00000 | 12.7300370 |  45.558205 | 0.000000e+00 | 0 | ⋯ |  161.6383500 |   0.000000 |  3.8299890 | 0 |   2.500017 |  0.00000000 | 0.3399987 |  0.2999976 |   0.0000000 | 0.000000 |\n",
       "| HN25_P5_F01_S61_comb |  0.0000000 | 1163.92790 | 0 | 27.9710520 |   0.000000 |  143.97241 |  2.3299760 |   0.000000 | 4.923079e+02 | 0 | ⋯ |  232.4138200 |   0.000000 |  5.0499635 | 0 |   0.000000 |  0.00000000 | 0.0000000 |  0.0000000 |  87.5809800 | 0.000000 |\n",
       "| HN26_P5_D12_S48_comb |  0.0000000 | 1195.92800 | 0 | 49.6614900 |   0.000000 |  420.72644 |  0.0000000 |   0.000000 | 6.908821e+02 | 0 | ⋯ |    0.0000000 |   0.000000 |  4.1399794 | 0 |   0.000000 |  0.00000000 | 0.6699987 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| HN25_P25_C11_S323_comb |  0.0000000 | 4091.76200 | 0 | 52.7580260 |   0.000000 |   41.57958 |  0.4099995 |   0.000000 | 1.287688e+03 | 0 | ⋯ |  221.4133100 |   0.000000 |  4.2700460 | 0 |   0.000000 | 76.02762600 | 1.9499949 |  0.0000000 | 254.8126200 | 0.000000 |\n",
       "| HN25_P25_B12_S312_comb | 38.6183200 |  348.30096 | 0 |  0.0000000 |   0.000000 |    0.00000 |  0.0000000 |   6.029951 | 0.000000e+00 | 0 | ⋯ |    0.0000000 |   0.000000 |  0.2400020 | 0 | 219.623750 |  0.09999795 | 0.2400020 |  0.0000000 |   0.0000000 | 0.000000 |\n",
       "| ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋱ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ |\n",
       "| HNSCC17_P4_A08_S104_comb |  98.22786 |  744.73590 | 0 |  0.000000 | 0 |  0.000000 | 18.6890470 |   0.000000 | 0.0000000 | 0 | ⋯ | 1196.346100 |  9.299989 | 0.4400021 |  29.880957 |  926.88495 |  0.2199986 | 0.5400010 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_E10_S154_comb |  84.82714 | 1044.26950 | 0 |  0.000000 | 0 |  0.000000 | 80.8004800 |   0.000000 | 0.0000000 | 0 | ⋯ | 5139.898000 | 24.359285 | 1.8900106 | 121.309555 | 2180.62700 |  0.1700023 | 1.3499819 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_E02_S146_comb |  24.34024 |  279.78278 | 0 |  0.000000 | 0 |  0.000000 |  0.0000000 |   0.000000 | 0.0000000 | 0 | ⋯ | 2884.559600 |  0.000000 | 0.0000000 |   0.000000 | 2420.48440 |  0.0000000 | 0.0000000 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P13_F10_S262_comb |  63.45191 |  123.65112 | 0 |  0.000000 | 0 |  0.000000 |  0.0000000 |   0.000000 | 0.0000000 | 0 | ⋯ |    0.000000 |  0.000000 | 2.1900158 |   0.000000 |  113.54802 |  0.4000034 | 0.6499968 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_D04_S136_comb | 136.26372 |  878.80804 | 0 | 23.281029 | 0 |  0.000000 |  3.6399655 |   0.000000 | 0.0000000 | 0 | ⋯ | 1967.727700 |  0.000000 | 0.7000015 | 136.354980 | 2629.46200 |  0.0000000 | 0.2199986 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P13_C06_S222_comb |  35.00858 |  289.77332 | 0 | 18.950735 | 0 |  0.000000 | 17.8407880 |  94.309600 | 0.0000000 | 0 | ⋯ |  472.313750 |  0.000000 | 2.5400230 |   0.000000 |  417.15863 | 48.3082500 | 0.0000000 | 0.4400021 | 0 | 0 |\n",
       "| HNSCC20_P13_C12_S228_comb |  34.80936 |  124.84219 | 0 |  0.000000 | 0 |  0.000000 |  0.0000000 |  55.350580 | 0.0000000 | 0 | ⋯ |  427.769650 |  0.000000 | 2.3900328 |   0.000000 |  481.56150 |  0.0000000 | 0.0000000 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_H04_S184_comb |  79.17875 |  228.26581 | 0 |  0.000000 | 0 |  0.000000 | 12.2206340 |   0.000000 | 0.0000000 | 0 | ⋯ |  642.090400 | 34.539950 | 0.1999989 |  13.729801 |  705.46040 |  0.0000000 | 0.1299988 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_C06_S126_comb |  62.65187 |  730.99915 | 0 |  8.150005 | 0 |  0.000000 | 17.4308620 |  39.160515 | 0.0000000 | 0 | ⋯ | 5796.399400 | 14.730647 | 0.0000000 |   2.679958 | 2165.04270 |  1.6399914 | 0.5600012 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P3_D01_S37_comb | 252.43713 |  122.98577 | 0 |  0.000000 | 0 |  0.000000 |  0.0000000 |  42.470260 | 0.0000000 | 0 | ⋯ |  388.580720 | 31.910160 | 0.5400010 |   0.000000 |   56.91826 |  0.0000000 | 0.5699973 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P3_D09_S45_comb | 214.97612 |  345.67804 | 0 |  0.000000 | 0 | 39.430450 |  0.0000000 |  54.768845 | 0.0000000 | 0 | ⋯ |  279.843050 | 14.629716 | 1.4999692 |   0.000000 |  116.74879 |  6.1600313 | 0.5200021 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_E06_S150_comb |  47.37014 |  692.34110 | 0 |  0.000000 | 0 |  0.000000 |  0.3600000 |   0.000000 | 0.0000000 | 0 | ⋯ | 1820.380700 |  5.510014 | 0.5900030 |  26.669992 | 1429.87520 |  0.0000000 | 0.1800031 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P13_H10_S286_comb | 101.81176 |  280.28537 | 0 |  0.000000 | 0 |  0.000000 | 31.8492000 |  83.320885 | 0.0000000 | 0 | ⋯ |  379.081360 | 21.520710 | 1.3100084 |   4.640045 |  235.62747 |  9.2300170 | 1.2300161 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_A02_S98_comb |  63.31966 |  321.88235 | 0 |  0.000000 | 0 |  0.000000 |  0.4900023 |  11.070142 | 0.0000000 | 0 | ⋯ |  623.511960 |  0.000000 | 1.5399742 |   0.000000 | 1446.63940 |  0.0000000 | 0.9099917 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P13_D01_S229_comb |  88.10998 |  164.50543 | 0 |  0.000000 | 0 | 12.610611 |  0.6699987 |   0.000000 | 0.0000000 | 0 | ⋯ |  183.491730 |  1.430036 | 1.2999783 |   0.000000 |  348.69855 |  0.8899701 | 0.8199962 | 0.7099965 | 0 | 0 |\n",
       "| HNSCC20_P13_G02_S266_comb | 186.69658 |  368.46814 | 0 |  0.000000 | 0 |  0.000000 | 32.1490480 | 108.342800 | 0.5600012 | 0 | ⋯ |  216.650910 |  0.000000 | 3.8500385 |   0.000000 |  183.86763 |  0.6699987 | 0.3700007 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_B04_S112_comb | 259.34810 |  905.76150 | 0 | 11.480089 | 0 |  0.000000 |  1.2399842 | 111.316180 | 0.0000000 | 0 | ⋯ | 2021.638700 |  0.000000 | 1.5199943 |   0.000000 |  288.23962 |  0.3200002 | 1.0599893 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_C09_S129_comb |  33.40015 | 1537.18300 | 0 |  0.000000 | 0 |  0.000000 |  9.3299780 |   0.000000 | 0.0000000 | 0 | ⋯ | 7199.722700 | 57.090103 | 1.0900049 |   0.000000 | 2257.56500 |  0.2699987 | 1.5599889 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P13_A12_S204_comb |  48.70974 |  222.84532 | 0 |  0.000000 | 0 |  0.000000 | 15.7701330 | 100.816440 | 0.0000000 | 0 | ⋯ |    9.459977 |  4.529953 | 2.5199604 |   0.000000 |  818.88495 |  0.0000000 | 0.4199980 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_F06_S162_comb | 145.57086 |  962.75190 | 0 |  1.330017 | 0 |  0.000000 | 63.9884450 | 141.989530 | 0.0000000 | 0 | ⋯ | 6650.100000 |  0.000000 | 1.4600235 |   0.000000 |  594.13540 |  0.0000000 | 0.6499968 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P3_B10_S22_comb | 186.75113 |  253.65875 | 0 |  0.000000 | 0 |  0.000000 | 15.6791950 |  65.391400 | 0.0000000 | 0 | ⋯ |  810.197800 |  4.499971 | 1.2300161 |   0.000000 |  156.13683 |  0.0000000 | 1.1100091 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P13_B11_S215_comb |  94.36022 |  483.98660 | 0 |  0.000000 | 0 |  0.000000 | 28.8792400 |  98.498260 | 0.0000000 | 0 | ⋯ |  455.142200 | 26.840689 | 2.4500368 |   0.000000 |  193.43556 |  1.0299786 | 0.4199980 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P3_C08_S32_comb | 350.46817 |  342.97644 | 0 |  0.000000 | 0 |  7.720017 | 54.4508800 |   1.999963 | 0.0000000 | 0 | ⋯ |  156.044720 | 36.508680 | 2.1799650 |   0.000000 |  524.16000 |  0.0000000 | 1.3599777 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_H03_S183_comb |  93.05196 | 1242.96300 | 0 |  0.000000 | 0 |  0.000000 |  0.0000000 |   0.000000 | 0.0000000 | 0 | ⋯ | 3388.136500 |  3.300035 | 0.0000000 |   0.000000 |  452.05734 |  0.1199980 | 0.0000000 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P3_F09_S69_comb |  60.96954 |  176.91365 | 0 |  0.000000 | 0 |  7.170000 |  0.0000000 |   0.000000 | 0.0000000 | 0 | ⋯ |  225.066990 |  0.000000 | 1.5399742 |   0.000000 |   84.84686 |  0.6100025 | 0.2799981 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_G12_S180_comb | 127.37999 |  902.90955 | 0 |  0.000000 | 0 |  0.000000 | 10.1698450 |   0.000000 | 0.0000000 | 0 | ⋯ |  222.136260 |  0.000000 | 2.1599727 |   0.000000 |  689.66870 |  0.4900023 | 1.5399742 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P13_C05_S221_comb | 106.59225 |  794.87897 | 0 |  0.000000 | 0 |  0.000000 |  0.0000000 |   0.000000 | 0.0000000 | 0 | ⋯ |  657.548160 |  0.000000 | 5.0300520 |   0.000000 |   85.36765 |  1.0299786 | 0.5699973 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC17_P4_C12_S132_comb | 270.20290 |  605.67630 | 0 |  0.000000 | 0 |  0.000000 | 30.1500000 |   0.000000 | 0.0000000 | 0 | ⋯ | 2413.419000 | 36.460350 | 0.2199986 |   0.000000 | 1068.43850 |  0.1199980 | 0.1400024 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P3_H08_S92_comb |  32.99891 |  272.60205 | 0 |  0.000000 | 0 |  0.000000 |  0.0000000 | 129.394330 | 0.0000000 | 0 | ⋯ |    0.000000 | 13.999428 | 2.2700405 |   0.000000 |    0.00000 |  0.5500000 | 0.5400010 | 0.0000000 | 0 | 0 |\n",
       "| HNSCC20_P3_G06_S78_comb | 129.81042 |   81.10941 | 0 |  0.000000 | 0 |  0.000000 |  0.0000000 | 526.534850 | 0.0000000 | 0 | ⋯ |   75.831070 |  4.959998 | 0.0000000 |   0.000000 |  195.76134 | 17.8890720 | 0.3900025 | 0.0000000 | 0 | 0 |\n",
       "\n"
      ],
      "text/plain": [
       "                          WDR66      CST3       ACTN2 CPEB4      TMEM176B  \n",
       "HN28_P15_D06_S330_comb     0.0000000  338.23758 0     30.3704590   0.000000\n",
       "HN28_P6_G05_S173_comb      0.0000000  456.30435 0     26.7896520   0.000000\n",
       "HN26_P14_D11_S239_comb     0.0000000  240.87555 0      0.1199980   0.000000\n",
       "HN26_P14_H05_S281_comb     0.0000000  325.28128 0      0.0000000   0.000000\n",
       "HN26_P25_H09_S189_comb     2.1799650  176.21533 0      0.0000000 157.049070\n",
       "HN26_P14_H06_S282_comb     0.0000000  330.83463 0      0.5699973  61.398808\n",
       "HN25_P25_C04_S316_comb    70.9707000 1289.21830 0      0.0000000   0.000000\n",
       "HN26_P25_A11_S107_comb     0.0000000   13.30921 0      2.9600384   0.000000\n",
       "HN26_P25_C09_S129_comb     0.0000000  108.90191 0      0.0000000   0.000000\n",
       "HNSCC26_P24_H05_S377_comb  0.0000000  236.66823 0     26.2102970   0.000000\n",
       "HN25_P5_E10_S58_comb       0.0000000 1413.50130 0     11.7106060   0.000000\n",
       "HN25_P24_B02_S110_comb    21.6191800  926.94990 0      9.2300170   0.000000\n",
       "HN25_P25_C01_S313_comb     0.0000000    0.00000 0     34.7100750   0.000000\n",
       "HN28_P15_G06_S366_comb     0.0000000  362.30164 0      0.0000000   0.000000\n",
       "HN26_P6_B06_S18_comb       0.0000000    0.00000 0      0.0000000   0.000000\n",
       "HN25_P5_C05_S29_comb       0.0000000 2177.89550 0     22.7092800  29.119827\n",
       "HN28_P6_D09_S141_comb      0.0000000  550.87213 0      0.0000000   0.000000\n",
       "HN26_P5_H01_S85_comb       0.6100025   54.54029 0      0.0000000   0.000000\n",
       "HN26_P13_D07_S139_comb     0.0000000  861.05990 0      0.0000000   0.000000\n",
       "HN26_P5_E06_S54_comb       0.0000000  226.58717 0      0.4900023   0.000000\n",
       "HN26_P26_H05_S377_comb     0.0000000  147.83005 0      0.5200021   5.350014\n",
       "HNSCC26_P24_F12_S360_comb  0.0000000  115.43778 0      0.0000000   0.000000\n",
       "HNSCC26_P24_F03_S351_comb  0.0000000  197.72458 0      0.0000000   0.000000\n",
       "HN26_P6_D08_S44_comb       0.0000000   96.76745 0     55.1515730   0.000000\n",
       "HN25_P5_E12_S60_comb       0.0000000 1086.37680 0     21.8899100   0.000000\n",
       "HNSCC26_P24_C01_S313_comb  0.0000000   57.51930 0      3.5000055   0.000000\n",
       "HN25_P5_F01_S61_comb       0.0000000 1163.92790 0     27.9710520   0.000000\n",
       "HN26_P5_D12_S48_comb       0.0000000 1195.92800 0     49.6614900   0.000000\n",
       "HN25_P25_C11_S323_comb     0.0000000 4091.76200 0     52.7580260   0.000000\n",
       "HN25_P25_B12_S312_comb    38.6183200  348.30096 0      0.0000000   0.000000\n",
       "⋮                         ⋮          ⋮          ⋮     ⋮          ⋮         \n",
       "HNSCC17_P4_A08_S104_comb   98.22786   744.73590 0      0.000000  0         \n",
       "HNSCC17_P4_E10_S154_comb   84.82714  1044.26950 0      0.000000  0         \n",
       "HNSCC17_P4_E02_S146_comb   24.34024   279.78278 0      0.000000  0         \n",
       "HNSCC20_P13_F10_S262_comb  63.45191   123.65112 0      0.000000  0         \n",
       "HNSCC17_P4_D04_S136_comb  136.26372   878.80804 0     23.281029  0         \n",
       "HNSCC20_P13_C06_S222_comb  35.00858   289.77332 0     18.950735  0         \n",
       "HNSCC20_P13_C12_S228_comb  34.80936   124.84219 0      0.000000  0         \n",
       "HNSCC17_P4_H04_S184_comb   79.17875   228.26581 0      0.000000  0         \n",
       "HNSCC17_P4_C06_S126_comb   62.65187   730.99915 0      8.150005  0         \n",
       "HNSCC20_P3_D01_S37_comb   252.43713   122.98577 0      0.000000  0         \n",
       "HNSCC20_P3_D09_S45_comb   214.97612   345.67804 0      0.000000  0         \n",
       "HNSCC17_P4_E06_S150_comb   47.37014   692.34110 0      0.000000  0         \n",
       "HNSCC20_P13_H10_S286_comb 101.81176   280.28537 0      0.000000  0         \n",
       "HNSCC17_P4_A02_S98_comb    63.31966   321.88235 0      0.000000  0         \n",
       "HNSCC20_P13_D01_S229_comb  88.10998   164.50543 0      0.000000  0         \n",
       "HNSCC20_P13_G02_S266_comb 186.69658   368.46814 0      0.000000  0         \n",
       "HNSCC17_P4_B04_S112_comb  259.34810   905.76150 0     11.480089  0         \n",
       "HNSCC17_P4_C09_S129_comb   33.40015  1537.18300 0      0.000000  0         \n",
       "HNSCC20_P13_A12_S204_comb  48.70974   222.84532 0      0.000000  0         \n",
       "HNSCC17_P4_F06_S162_comb  145.57086   962.75190 0      1.330017  0         \n",
       "HNSCC20_P3_B10_S22_comb   186.75113   253.65875 0      0.000000  0         \n",
       "HNSCC20_P13_B11_S215_comb  94.36022   483.98660 0      0.000000  0         \n",
       "HNSCC20_P3_C08_S32_comb   350.46817   342.97644 0      0.000000  0         \n",
       "HNSCC17_P4_H03_S183_comb   93.05196  1242.96300 0      0.000000  0         \n",
       "HNSCC20_P3_F09_S69_comb    60.96954   176.91365 0      0.000000  0         \n",
       "HNSCC17_P4_G12_S180_comb  127.37999   902.90955 0      0.000000  0         \n",
       "HNSCC20_P13_C05_S221_comb 106.59225   794.87897 0      0.000000  0         \n",
       "HNSCC17_P4_C12_S132_comb  270.20290   605.67630 0      0.000000  0         \n",
       "HNSCC20_P3_H08_S92_comb    32.99891   272.60205 0      0.000000  0         \n",
       "HNSCC20_P3_G06_S78_comb   129.81042    81.10941 0      0.000000  0         \n",
       "                          COL6A2     BAG1       PELI1      COL3A1      \n",
       "HN28_P15_D06_S330_comb      37.35117  0.0000000   0.000000 1.133014e+03\n",
       "HN28_P6_G05_S173_comb       76.78827  0.0000000   0.000000 6.960726e+01\n",
       "HN26_P14_D11_S239_comb       0.00000 17.1302050  89.783410 0.000000e+00\n",
       "HN26_P14_H05_S281_comb      72.78102  0.5100024   2.110009 2.895213e+03\n",
       "HN26_P25_H09_S189_comb      39.33119 76.3382600   4.290040 0.000000e+00\n",
       "HN26_P14_H06_S282_comb       0.00000 80.9201400   0.000000 0.000000e+00\n",
       "HN25_P25_C04_S316_comb    1140.32680  1.6500003   0.000000 0.000000e+00\n",
       "HN26_P25_A11_S107_comb      56.29959  0.9499934   0.000000 6.500485e+02\n",
       "HN26_P25_C09_S129_comb       0.00000 52.1907500  78.073010 0.000000e+00\n",
       "HNSCC26_P24_H05_S377_comb    0.00000  0.0000000 197.364930 0.000000e+00\n",
       "HN25_P5_E10_S58_comb        48.79119 52.0013660  92.930595 2.056865e+03\n",
       "HN25_P24_B02_S110_comb       0.00000 20.9405750  23.740936 0.000000e+00\n",
       "HN25_P25_C01_S313_comb       0.00000  0.0000000 569.404900 0.000000e+00\n",
       "HN28_P15_G06_S366_comb      87.00775  0.9899895   0.000000 1.391376e+03\n",
       "HN26_P6_B06_S18_comb        27.09951  0.9099917   0.000000 0.000000e+00\n",
       "HN25_P5_C05_S29_comb       185.43271  0.0000000  64.990090 1.247517e+04\n",
       "HN28_P6_D09_S141_comb        0.00000  2.1000247   0.000000 1.450019e+00\n",
       "HN26_P5_H01_S85_comb         0.00000  0.0000000  76.938790 0.000000e+00\n",
       "HN26_P13_D07_S139_comb     173.53712  0.0000000   0.000000 0.000000e+00\n",
       "HN26_P5_E06_S54_comb         0.00000 36.4088500  91.050180 0.000000e+00\n",
       "HN26_P26_H05_S377_comb      11.68053 48.7504540  77.671020 0.000000e+00\n",
       "HNSCC26_P24_F12_S360_comb    0.00000  0.5999981   0.000000 0.000000e+00\n",
       "HNSCC26_P24_F03_S351_comb    0.00000  0.0000000 109.919970 0.000000e+00\n",
       "HN26_P6_D08_S44_comb         0.00000 37.7201960 204.335660 1.899996e-01\n",
       "HN25_P5_E12_S60_comb       120.21286  0.0000000   1.330017 1.082690e+02\n",
       "HNSCC26_P24_C01_S313_comb    0.00000 12.7300370  45.558205 0.000000e+00\n",
       "HN25_P5_F01_S61_comb       143.97241  2.3299760   0.000000 4.923079e+02\n",
       "HN26_P5_D12_S48_comb       420.72644  0.0000000   0.000000 6.908821e+02\n",
       "HN25_P25_C11_S323_comb      41.57958  0.4099995   0.000000 1.287688e+03\n",
       "HN25_P25_B12_S312_comb       0.00000  0.0000000   6.029951 0.000000e+00\n",
       "⋮                         ⋮          ⋮          ⋮          ⋮           \n",
       "HNSCC17_P4_A08_S104_comb   0.000000  18.6890470   0.000000 0.0000000   \n",
       "HNSCC17_P4_E10_S154_comb   0.000000  80.8004800   0.000000 0.0000000   \n",
       "HNSCC17_P4_E02_S146_comb   0.000000   0.0000000   0.000000 0.0000000   \n",
       "HNSCC20_P13_F10_S262_comb  0.000000   0.0000000   0.000000 0.0000000   \n",
       "HNSCC17_P4_D04_S136_comb   0.000000   3.6399655   0.000000 0.0000000   \n",
       "HNSCC20_P13_C06_S222_comb  0.000000  17.8407880  94.309600 0.0000000   \n",
       "HNSCC20_P13_C12_S228_comb  0.000000   0.0000000  55.350580 0.0000000   \n",
       "HNSCC17_P4_H04_S184_comb   0.000000  12.2206340   0.000000 0.0000000   \n",
       "HNSCC17_P4_C06_S126_comb   0.000000  17.4308620  39.160515 0.0000000   \n",
       "HNSCC20_P3_D01_S37_comb    0.000000   0.0000000  42.470260 0.0000000   \n",
       "HNSCC20_P3_D09_S45_comb   39.430450   0.0000000  54.768845 0.0000000   \n",
       "HNSCC17_P4_E06_S150_comb   0.000000   0.3600000   0.000000 0.0000000   \n",
       "HNSCC20_P13_H10_S286_comb  0.000000  31.8492000  83.320885 0.0000000   \n",
       "HNSCC17_P4_A02_S98_comb    0.000000   0.4900023  11.070142 0.0000000   \n",
       "HNSCC20_P13_D01_S229_comb 12.610611   0.6699987   0.000000 0.0000000   \n",
       "HNSCC20_P13_G02_S266_comb  0.000000  32.1490480 108.342800 0.5600012   \n",
       "HNSCC17_P4_B04_S112_comb   0.000000   1.2399842 111.316180 0.0000000   \n",
       "HNSCC17_P4_C09_S129_comb   0.000000   9.3299780   0.000000 0.0000000   \n",
       "HNSCC20_P13_A12_S204_comb  0.000000  15.7701330 100.816440 0.0000000   \n",
       "HNSCC17_P4_F06_S162_comb   0.000000  63.9884450 141.989530 0.0000000   \n",
       "HNSCC20_P3_B10_S22_comb    0.000000  15.6791950  65.391400 0.0000000   \n",
       "HNSCC20_P13_B11_S215_comb  0.000000  28.8792400  98.498260 0.0000000   \n",
       "HNSCC20_P3_C08_S32_comb    7.720017  54.4508800   1.999963 0.0000000   \n",
       "HNSCC17_P4_H03_S183_comb   0.000000   0.0000000   0.000000 0.0000000   \n",
       "HNSCC20_P3_F09_S69_comb    7.170000   0.0000000   0.000000 0.0000000   \n",
       "HNSCC17_P4_G12_S180_comb   0.000000  10.1698450   0.000000 0.0000000   \n",
       "HNSCC20_P13_C05_S221_comb  0.000000   0.0000000   0.000000 0.0000000   \n",
       "HNSCC17_P4_C12_S132_comb   0.000000  30.1500000   0.000000 0.0000000   \n",
       "HNSCC20_P3_H08_S92_comb    0.000000   0.0000000 129.394330 0.0000000   \n",
       "HNSCC20_P3_G06_S78_comb    0.000000   0.0000000 526.534850 0.0000000   \n",
       "                          SIGLEC17P ⋯ GLUL         LMO7       ATCAY     \n",
       "HN28_P15_D06_S330_comb    0         ⋯   50.4691800   0.000000  1.9999634\n",
       "HN28_P6_G05_S173_comb     0         ⋯  287.2902000   0.000000  2.7299786\n",
       "HN26_P14_D11_S239_comb    0         ⋯  153.9518100   0.000000  1.1000025\n",
       "HN26_P14_H05_S281_comb    0         ⋯ 1514.4025000   0.000000  1.6199994\n",
       "HN26_P25_H09_S189_comb    0         ⋯  175.1856000   0.000000  1.7199792\n",
       "HN26_P14_H06_S282_comb    0         ⋯  306.4926500   0.000000  0.7099965\n",
       "HN25_P25_C04_S316_comb    0         ⋯    0.0000000   0.000000 10.1796340\n",
       "HN26_P25_A11_S107_comb    0         ⋯    5.8499690   0.000000  4.4099965\n",
       "HN26_P25_C09_S129_comb    0         ⋯  208.9151600   0.000000  1.5299800\n",
       "HNSCC26_P24_H05_S377_comb 0         ⋯    0.8599691   0.000000  4.1000470\n",
       "HN25_P5_E10_S58_comb      0         ⋯  194.9215900   0.000000  1.6299912\n",
       "HN25_P24_B02_S110_comb    0         ⋯    0.0000000   0.000000  0.5400010\n",
       "HN25_P25_C01_S313_comb    0         ⋯    0.0000000   0.000000  3.8299890\n",
       "HN28_P15_G06_S366_comb    0         ⋯  455.4325000   0.000000  1.6399914\n",
       "HN26_P6_B06_S18_comb      0         ⋯    0.0000000   0.000000  4.4600244\n",
       "HN25_P5_C05_S29_comb      0         ⋯  142.2003800   0.000000  1.4199790\n",
       "HN28_P6_D09_S141_comb     0         ⋯ 1068.3636000   0.000000  5.9099580\n",
       "HN26_P5_H01_S85_comb      0         ⋯  167.5311100   0.000000  4.3199854\n",
       "HN26_P13_D07_S139_comb    0         ⋯    0.0000000   0.000000  4.5199850\n",
       "HN26_P5_E06_S54_comb      0         ⋯  542.3459000  28.280243  1.4500190\n",
       "HN26_P26_H05_S377_comb    0         ⋯   98.4907400   2.780019  1.5999614\n",
       "HNSCC26_P24_F12_S360_comb 0         ⋯  195.4762900   0.000000  1.0599893\n",
       "HNSCC26_P24_F03_S351_comb 0         ⋯  220.4369200   0.000000  3.3800175\n",
       "HN26_P6_D08_S44_comb      0         ⋯    0.0000000 117.462420  3.4399707\n",
       "HN25_P5_E12_S60_comb      0         ⋯   85.3610400   0.000000  3.9200077\n",
       "HNSCC26_P24_C01_S313_comb 0         ⋯  161.6383500   0.000000  3.8299890\n",
       "HN25_P5_F01_S61_comb      0         ⋯  232.4138200   0.000000  5.0499635\n",
       "HN26_P5_D12_S48_comb      0         ⋯    0.0000000   0.000000  4.1399794\n",
       "HN25_P25_C11_S323_comb    0         ⋯  221.4133100   0.000000  4.2700460\n",
       "HN25_P25_B12_S312_comb    0         ⋯    0.0000000   0.000000  0.2400020\n",
       "⋮                         ⋮         ⋱ ⋮            ⋮          ⋮         \n",
       "HNSCC17_P4_A08_S104_comb  0         ⋯ 1196.346100   9.299989  0.4400021 \n",
       "HNSCC17_P4_E10_S154_comb  0         ⋯ 5139.898000  24.359285  1.8900106 \n",
       "HNSCC17_P4_E02_S146_comb  0         ⋯ 2884.559600   0.000000  0.0000000 \n",
       "HNSCC20_P13_F10_S262_comb 0         ⋯    0.000000   0.000000  2.1900158 \n",
       "HNSCC17_P4_D04_S136_comb  0         ⋯ 1967.727700   0.000000  0.7000015 \n",
       "HNSCC20_P13_C06_S222_comb 0         ⋯  472.313750   0.000000  2.5400230 \n",
       "HNSCC20_P13_C12_S228_comb 0         ⋯  427.769650   0.000000  2.3900328 \n",
       "HNSCC17_P4_H04_S184_comb  0         ⋯  642.090400  34.539950  0.1999989 \n",
       "HNSCC17_P4_C06_S126_comb  0         ⋯ 5796.399400  14.730647  0.0000000 \n",
       "HNSCC20_P3_D01_S37_comb   0         ⋯  388.580720  31.910160  0.5400010 \n",
       "HNSCC20_P3_D09_S45_comb   0         ⋯  279.843050  14.629716  1.4999692 \n",
       "HNSCC17_P4_E06_S150_comb  0         ⋯ 1820.380700   5.510014  0.5900030 \n",
       "HNSCC20_P13_H10_S286_comb 0         ⋯  379.081360  21.520710  1.3100084 \n",
       "HNSCC17_P4_A02_S98_comb   0         ⋯  623.511960   0.000000  1.5399742 \n",
       "HNSCC20_P13_D01_S229_comb 0         ⋯  183.491730   1.430036  1.2999783 \n",
       "HNSCC20_P13_G02_S266_comb 0         ⋯  216.650910   0.000000  3.8500385 \n",
       "HNSCC17_P4_B04_S112_comb  0         ⋯ 2021.638700   0.000000  1.5199943 \n",
       "HNSCC17_P4_C09_S129_comb  0         ⋯ 7199.722700  57.090103  1.0900049 \n",
       "HNSCC20_P13_A12_S204_comb 0         ⋯    9.459977   4.529953  2.5199604 \n",
       "HNSCC17_P4_F06_S162_comb  0         ⋯ 6650.100000   0.000000  1.4600235 \n",
       "HNSCC20_P3_B10_S22_comb   0         ⋯  810.197800   4.499971  1.2300161 \n",
       "HNSCC20_P13_B11_S215_comb 0         ⋯  455.142200  26.840689  2.4500368 \n",
       "HNSCC20_P3_C08_S32_comb   0         ⋯  156.044720  36.508680  2.1799650 \n",
       "HNSCC17_P4_H03_S183_comb  0         ⋯ 3388.136500   3.300035  0.0000000 \n",
       "HNSCC20_P3_F09_S69_comb   0         ⋯  225.066990   0.000000  1.5399742 \n",
       "HNSCC17_P4_G12_S180_comb  0         ⋯  222.136260   0.000000  2.1599727 \n",
       "HNSCC20_P13_C05_S221_comb 0         ⋯  657.548160   0.000000  5.0300520 \n",
       "HNSCC17_P4_C12_S132_comb  0         ⋯ 2413.419000  36.460350  0.2199986 \n",
       "HNSCC20_P3_H08_S92_comb   0         ⋯    0.000000  13.999428  2.2700405 \n",
       "HNSCC20_P3_G06_S78_comb   0         ⋯   75.831070   4.959998  0.0000000 \n",
       "                          MCTP1      SERPINB5   ADRBK2      CD84     \n",
       "HN28_P15_D06_S330_comb    0            0.000000  0.35999998 0.8199962\n",
       "HN28_P6_G05_S173_comb     0            0.000000  1.23998420 0.0000000\n",
       "HN26_P14_D11_S239_comb    0           77.422220  0.08000252 0.6499968\n",
       "HN26_P14_H05_S281_comb    0            0.000000  0.21999861 0.9899895\n",
       "HN26_P25_H09_S189_comb    0          394.733400  0.00000000 0.5999981\n",
       "HN26_P14_H06_S282_comb    0          190.384640  0.00000000 0.7099965\n",
       "HN25_P25_C04_S316_comb    0           16.039469  0.78996360 6.7499870\n",
       "HN26_P25_A11_S107_comb    0            0.000000 36.55060600 1.0800163\n",
       "HN26_P25_C09_S129_comb    0          127.541970  0.17000227 0.7000015\n",
       "HNSCC26_P24_H05_S377_comb 0           96.693474  0.37000075 2.4899700\n",
       "HN25_P5_E10_S58_comb      0            1.580038  0.00000000 2.6299593\n",
       "HN25_P24_B02_S110_comb    0          378.084800  0.21000095 0.0000000\n",
       "HN25_P25_C01_S313_comb    0            0.000000  0.88997010 0.9499934\n",
       "HN28_P15_G06_S366_comb    0            0.000000  0.00000000 0.9699732\n",
       "HN26_P6_B06_S18_comb      0            0.000000  0.73997027 0.0000000\n",
       "HN25_P5_C05_S29_comb      0            0.000000  0.48000205 1.8299994\n",
       "HN28_P6_D09_S141_comb     0            0.000000  0.00000000 0.9600167\n",
       "HN26_P5_H01_S85_comb      0          192.226470  0.26999870 1.4199790\n",
       "HN26_P13_D07_S139_comb    0            0.000000  0.00000000 1.4799789\n",
       "HN26_P5_E06_S54_comb      0           93.610620  0.52999680 0.2999976\n",
       "HN26_P26_H05_S377_comb    0          138.779100  0.00000000 0.6900011\n",
       "HNSCC26_P24_F12_S360_comb 0            0.000000  0.29000014 0.8800109\n",
       "HNSCC26_P24_F03_S351_comb 0          384.923130  0.75002490 1.5199943\n",
       "HN26_P6_D08_S44_comb      0            0.000000  0.11999796 1.0700366\n",
       "HN25_P5_E12_S60_comb      0            0.000000  0.00000000 0.6200017\n",
       "HNSCC26_P24_C01_S313_comb 0            2.500017  0.00000000 0.3399987\n",
       "HN25_P5_F01_S61_comb      0            0.000000  0.00000000 0.0000000\n",
       "HN26_P5_D12_S48_comb      0            0.000000  0.00000000 0.6699987\n",
       "HN25_P25_C11_S323_comb    0            0.000000 76.02762600 1.9499949\n",
       "HN25_P25_B12_S312_comb    0          219.623750  0.09999795 0.2400020\n",
       "⋮                         ⋮          ⋮          ⋮           ⋮        \n",
       "HNSCC17_P4_A08_S104_comb   29.880957  926.88495  0.2199986  0.5400010\n",
       "HNSCC17_P4_E10_S154_comb  121.309555 2180.62700  0.1700023  1.3499819\n",
       "HNSCC17_P4_E02_S146_comb    0.000000 2420.48440  0.0000000  0.0000000\n",
       "HNSCC20_P13_F10_S262_comb   0.000000  113.54802  0.4000034  0.6499968\n",
       "HNSCC17_P4_D04_S136_comb  136.354980 2629.46200  0.0000000  0.2199986\n",
       "HNSCC20_P13_C06_S222_comb   0.000000  417.15863 48.3082500  0.0000000\n",
       "HNSCC20_P13_C12_S228_comb   0.000000  481.56150  0.0000000  0.0000000\n",
       "HNSCC17_P4_H04_S184_comb   13.729801  705.46040  0.0000000  0.1299988\n",
       "HNSCC17_P4_C06_S126_comb    2.679958 2165.04270  1.6399914  0.5600012\n",
       "HNSCC20_P3_D01_S37_comb     0.000000   56.91826  0.0000000  0.5699973\n",
       "HNSCC20_P3_D09_S45_comb     0.000000  116.74879  6.1600313  0.5200021\n",
       "HNSCC17_P4_E06_S150_comb   26.669992 1429.87520  0.0000000  0.1800031\n",
       "HNSCC20_P13_H10_S286_comb   4.640045  235.62747  9.2300170  1.2300161\n",
       "HNSCC17_P4_A02_S98_comb     0.000000 1446.63940  0.0000000  0.9099917\n",
       "HNSCC20_P13_D01_S229_comb   0.000000  348.69855  0.8899701  0.8199962\n",
       "HNSCC20_P13_G02_S266_comb   0.000000  183.86763  0.6699987  0.3700007\n",
       "HNSCC17_P4_B04_S112_comb    0.000000  288.23962  0.3200002  1.0599893\n",
       "HNSCC17_P4_C09_S129_comb    0.000000 2257.56500  0.2699987  1.5599889\n",
       "HNSCC20_P13_A12_S204_comb   0.000000  818.88495  0.0000000  0.4199980\n",
       "HNSCC17_P4_F06_S162_comb    0.000000  594.13540  0.0000000  0.6499968\n",
       "HNSCC20_P3_B10_S22_comb     0.000000  156.13683  0.0000000  1.1100091\n",
       "HNSCC20_P13_B11_S215_comb   0.000000  193.43556  1.0299786  0.4199980\n",
       "HNSCC20_P3_C08_S32_comb     0.000000  524.16000  0.0000000  1.3599777\n",
       "HNSCC17_P4_H03_S183_comb    0.000000  452.05734  0.1199980  0.0000000\n",
       "HNSCC20_P3_F09_S69_comb     0.000000   84.84686  0.6100025  0.2799981\n",
       "HNSCC17_P4_G12_S180_comb    0.000000  689.66870  0.4900023  1.5399742\n",
       "HNSCC20_P13_C05_S221_comb   0.000000   85.36765  1.0299786  0.5699973\n",
       "HNSCC17_P4_C12_S132_comb    0.000000 1068.43850  0.1199980  0.1400024\n",
       "HNSCC20_P3_H08_S92_comb     0.000000    0.00000  0.5500000  0.5400010\n",
       "HNSCC20_P3_G06_S78_comb     0.000000  195.76134 17.8890720  0.3900025\n",
       "                          FAM105A    ZEB2        HLA-DQA2\n",
       "HN28_P15_D06_S330_comb     0.0000000   0.0000000 0.000000\n",
       "HN28_P6_G05_S173_comb      0.0000000   0.0000000 0.000000\n",
       "HN26_P14_D11_S239_comb     0.0000000   0.0000000 1.070037\n",
       "HN26_P14_H05_S281_comb     0.0000000  96.3980600 0.000000\n",
       "HN26_P25_H09_S189_comb     0.0000000   0.0000000 4.249981\n",
       "HN26_P14_H06_S282_comb     0.0000000   0.0000000 0.000000\n",
       "HN25_P25_C04_S316_comb     0.0000000   0.0000000 0.000000\n",
       "HN26_P25_A11_S107_comb     0.0000000   0.0000000 0.000000\n",
       "HN26_P25_C09_S129_comb     0.1899996   0.0000000 0.000000\n",
       "HNSCC26_P24_H05_S377_comb  0.0000000   0.0000000 0.000000\n",
       "HN25_P5_E10_S58_comb       0.0000000  67.7692600 0.000000\n",
       "HN25_P24_B02_S110_comb     0.0000000   0.0000000 0.000000\n",
       "HN25_P25_C01_S313_comb     0.0000000   0.0000000 0.000000\n",
       "HN28_P15_G06_S366_comb     0.0000000   0.0000000 0.000000\n",
       "HN26_P6_B06_S18_comb       0.0000000 542.5756000 0.000000\n",
       "HN25_P5_C05_S29_comb      39.8191380   0.8800109 0.000000\n",
       "HN28_P6_D09_S141_comb      0.0000000   0.0000000 0.000000\n",
       "HN26_P5_H01_S85_comb       0.0000000   0.0000000 0.000000\n",
       "HN26_P13_D07_S139_comb     0.0000000  77.5070950 0.000000\n",
       "HN26_P5_E06_S54_comb       0.0000000   0.0000000 2.070036\n",
       "HN26_P26_H05_S377_comb     0.0000000   0.0000000 5.810029\n",
       "HNSCC26_P24_F12_S360_comb  0.2900001   0.0000000 0.000000\n",
       "HNSCC26_P24_F03_S351_comb  0.0000000   0.0000000 0.000000\n",
       "HN26_P6_D08_S44_comb       0.0000000   0.0000000 0.000000\n",
       "HN25_P5_E12_S60_comb       0.0000000  67.3982000 0.000000\n",
       "HNSCC26_P24_C01_S313_comb  0.2999976   0.0000000 0.000000\n",
       "HN25_P5_F01_S61_comb       0.0000000  87.5809800 0.000000\n",
       "HN26_P5_D12_S48_comb       0.0000000   0.0000000 0.000000\n",
       "HN25_P25_C11_S323_comb     0.0000000 254.8126200 0.000000\n",
       "HN25_P25_B12_S312_comb     0.0000000   0.0000000 0.000000\n",
       "⋮                         ⋮          ⋮           ⋮       \n",
       "HNSCC17_P4_A08_S104_comb  0.0000000  0           0       \n",
       "HNSCC17_P4_E10_S154_comb  0.0000000  0           0       \n",
       "HNSCC17_P4_E02_S146_comb  0.0000000  0           0       \n",
       "HNSCC20_P13_F10_S262_comb 0.0000000  0           0       \n",
       "HNSCC17_P4_D04_S136_comb  0.0000000  0           0       \n",
       "HNSCC20_P13_C06_S222_comb 0.4400021  0           0       \n",
       "HNSCC20_P13_C12_S228_comb 0.0000000  0           0       \n",
       "HNSCC17_P4_H04_S184_comb  0.0000000  0           0       \n",
       "HNSCC17_P4_C06_S126_comb  0.0000000  0           0       \n",
       "HNSCC20_P3_D01_S37_comb   0.0000000  0           0       \n",
       "HNSCC20_P3_D09_S45_comb   0.0000000  0           0       \n",
       "HNSCC17_P4_E06_S150_comb  0.0000000  0           0       \n",
       "HNSCC20_P13_H10_S286_comb 0.0000000  0           0       \n",
       "HNSCC17_P4_A02_S98_comb   0.0000000  0           0       \n",
       "HNSCC20_P13_D01_S229_comb 0.7099965  0           0       \n",
       "HNSCC20_P13_G02_S266_comb 0.0000000  0           0       \n",
       "HNSCC17_P4_B04_S112_comb  0.0000000  0           0       \n",
       "HNSCC17_P4_C09_S129_comb  0.0000000  0           0       \n",
       "HNSCC20_P13_A12_S204_comb 0.0000000  0           0       \n",
       "HNSCC17_P4_F06_S162_comb  0.0000000  0           0       \n",
       "HNSCC20_P3_B10_S22_comb   0.0000000  0           0       \n",
       "HNSCC20_P13_B11_S215_comb 0.0000000  0           0       \n",
       "HNSCC20_P3_C08_S32_comb   0.0000000  0           0       \n",
       "HNSCC17_P4_H03_S183_comb  0.0000000  0           0       \n",
       "HNSCC20_P3_F09_S69_comb   0.0000000  0           0       \n",
       "HNSCC17_P4_G12_S180_comb  0.0000000  0           0       \n",
       "HNSCC20_P13_C05_S221_comb 0.0000000  0           0       \n",
       "HNSCC17_P4_C12_S132_comb  0.0000000  0           0       \n",
       "HNSCC20_P3_H08_S92_comb   0.0000000  0           0       \n",
       "HNSCC20_P3_G06_S78_comb   0.0000000  0           0       "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "ref.data.filtered"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 127,
   "id": "b33b824a",
   "metadata": {},
   "outputs": [],
   "source": [
    "# ?run.Ted"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 41,
   "id": "77bb9c43",
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "[1] \"removing non-numeric genes...\"\n",
      "[1] \"removing outlier genes...\"\n",
      "Number of outlier genes filtered= 7 \n",
      "[1] \"aligning reference and mixture...\"\n",
      "[1] \"run first sampling\"\n",
      "Start run... This may take a while \n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "snowfall 1.84-6.2 initialized (using snow 0.4-4): parallel execution on 12 CPUs.\n",
      "\n",
      "\n",
      "\n",
      "Stopping cluster\n",
      "\n",
      "\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "[1] \"merge subtypes\"\n",
      "        Fibroblast tumor tconv.cells Macrophage Endothelial b.cells cd14.cells\n",
      "Min.         0.000 0.000       0.000      0.000       0.001   0.000      0.000\n",
      "1st Qu.      0.045 0.552       0.000      0.008       0.024   0.000      0.000\n",
      "Median       0.115 0.721       0.004      0.030       0.041   0.000      0.000\n",
      "Mean         0.156 0.681       0.049      0.055       0.047   0.002      0.001\n",
      "3rd Qu.      0.217 0.847       0.028      0.087       0.061   0.001      0.000\n",
      "Max.         0.933 0.996       0.859      0.370       0.202   0.053      0.067\n",
      "        cd8.cells treg.cells mast.cells pdc.cells nk.cells\n",
      "Min.        0.000      0.000      0.000     0.000    0.000\n",
      "1st Qu.     0.000      0.000      0.000     0.000    0.000\n",
      "Median      0.001      0.000      0.000     0.000    0.000\n",
      "Mean        0.006      0.001      0.000     0.001    0.001\n",
      "3rd Qu.     0.007      0.000      0.000     0.001    0.001\n",
      "Max.        0.079      0.054      0.003     0.039    0.038\n",
      "[1] \"pooling information across samples\"\n",
      "Start optimization... This may take a while \n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "snowfall 1.84-6.2 initialized (using snow 0.4-4): parallel execution on 12 CPUs.\n",
      "\n",
      "\n",
      "\n",
      "Stopping cluster\n",
      "\n",
      "\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "[1] \"run final sampling\"\n",
      "Start run... This may take a while \n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "snowfall 1.84-6.2 initialized (using snow 0.4-4): parallel execution on 12 CPUs.\n",
      "\n",
      "\n",
      "\n",
      "Stopping cluster\n",
      "\n",
      "\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "        tumor Fibroblast tconv.cells Macrophage Endothelial b.cells cd14.cells\n",
      "Min.    0.012      0.000       0.000      0.000       0.000   0.000      0.000\n",
      "1st Qu. 0.601      0.029       0.000      0.006       0.022   0.000      0.000\n",
      "Median  0.769      0.087       0.000      0.025       0.035   0.000      0.000\n",
      "Mean    0.717      0.137       0.039      0.046       0.041   0.002      0.002\n",
      "3rd Qu. 0.874      0.189       0.012      0.067       0.053   0.002      0.000\n",
      "Max.    0.996      0.930       0.879      0.325       0.172   0.053      0.082\n",
      "        cd8.cells treg.cells mast.cells pdc.cells nk.cells\n",
      "Min.        0.000      0.000      0.000     0.000    0.000\n",
      "1st Qu.     0.001      0.000      0.000     0.000    0.000\n",
      "Median      0.003      0.000      0.000     0.001    0.001\n",
      "Mean        0.006      0.003      0.000     0.003    0.003\n",
      "3rd Qu.     0.008      0.003      0.001     0.003    0.004\n",
      "Max.        0.081      0.049      0.004     0.063    0.031\n",
      "[1] \"every gene has at least one zero. vst transformation is NOT feasible\"\n"
     ]
    }
   ],
   "source": [
    "#run BayesPrism main func\n",
    "res <- run.Ted(ref.dat=ref.data.filtered, X=df_TCGA,cell.type.labels=label_subtype$Ingest_prediction,\n",
    "               tum.key='tumor',input.type=\"scRNA\",n.cores=12,pdf.name=\"PuramTCGA\",seed=52322)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 49,
   "id": "9c4682f3",
   "metadata": {},
   "outputs": [],
   "source": [
    "saveRDS(res,\"/home/cke/Real/TCGAResults/BayesPrism/BP_ImmuneSubtypes_real_Aug8_res.rds\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "id": "1c5d6f35",
   "metadata": {},
   "outputs": [],
   "source": []
  },
  {
   "cell_type": "markdown",
   "id": "1e57257f",
   "metadata": {},
   "source": [
    "### A list of result is returned in this function.\n",
    "\n",
    "para\t\n",
    "All input data and parameters.\n",
    "\n",
    "res\t\n",
    "All output of TED.\n",
    "\n",
    "res$first.gibbs.res$gibbs.theta\t\n",
    "Initial estimates of fraction for all cell subtypes in each bulk sample.\n",
    "\n",
    "res$first.gibbs.res$Znkg\t\n",
    "Initial estimates of the mean of posterior read count for each cell subtypes in each bulk sample.\n",
    "\n",
    "res$first.gibbs.res$theta.merged\t\n",
    "Initial estimates of fraction summed across cell types in each bulk sample.\n",
    "\n",
    "res$first.gibbs.res$Znkg.merged\t\n",
    "Initial estimates of the mean of posterior read count summed across cell types in each bulk sample.\n",
    "\n",
    "res$Zkg.tum\t\n",
    "Mean of posterior of gene expression of tumor in each patient.\n",
    "\n",
    "res$Zkg.tum.norm\t\n",
    "Depth normalized Zkg.tum (A pseudo count is added, such that the zero-valued genes have the same value as the min(phi.input)). Refered to as the psi.tum in the TED paper)\n",
    "\n",
    "res$Zkg.tum.vst\t\n",
    "Variance stablized transformed value of Zkg.tum. If vst transformation is not feasible, return NULL.\n",
    "\n",
    "res$phi.env\t\n",
    "Batch effect corrected expression profiles of stromal cells (refered to as the psi.str in the TED paper)\n",
    "\n",
    "res$final.gibbs.theta\t\n",
    "Updated theta after batch correction and tumor expression estimates.\n",
    "\n",
    "res$cor.mat\t\n",
    "The correlation matrix of the estimated tumor expression profiles across bulk RNA-seq samples."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 6,
   "id": "8ad176b7",
   "metadata": {},
   "outputs": [],
   "source": [
    "res <- readRDS(\"/home/cke/Real/TCGAResults/BayesPrism/BP_ImmuneSubtypes_real_Aug8_res.rds\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 43,
   "id": "ac92bbf4",
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<table class=\"dataframe\">\n",
       "<caption>A matrix: 546 × 12 of type dbl</caption>\n",
       "<thead>\n",
       "\t<tr><th></th><th scope=col>tumor</th><th scope=col>Fibroblast</th><th scope=col>tconv.cells</th><th scope=col>Macrophage</th><th scope=col>Endothelial</th><th scope=col>b.cells</th><th scope=col>cd14.cells</th><th scope=col>cd8.cells</th><th scope=col>treg.cells</th><th scope=col>mast.cells</th><th scope=col>pdc.cells</th><th scope=col>nk.cells</th></tr>\n",
       "</thead>\n",
       "<tbody>\n",
       "\t<tr><th scope=row>TCGA-BB-4224-01A</th><td>0.92733662</td><td>0.0190890154</td><td>6.065475e-03</td><td>1.667066e-02</td><td>0.01899481</td><td>7.521237e-07</td><td>2.923092e-05</td><td>5.354050e-03</td><td>3.046525e-04</td><td>1.783831e-04</td><td>1.032630e-03</td><td>4.943720e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-H7-7774-01A</th><td>0.96023355</td><td>0.0005243755</td><td>5.746715e-07</td><td>1.726243e-02</td><td>0.01281692</td><td>2.474022e-04</td><td>1.642298e-05</td><td>6.565494e-03</td><td>7.144899e-04</td><td>5.097020e-04</td><td>1.077549e-03</td><td>3.108857e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6943-01A</th><td>0.42282326</td><td>0.3809782307</td><td>2.688987e-07</td><td>1.322473e-01</td><td>0.03871532</td><td>3.798463e-03</td><td>4.150265e-06</td><td>1.605742e-02</td><td>1.883073e-03</td><td>7.728221e-04</td><td>2.718970e-03</td><td>7.299435e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-5374-01A</th><td>0.83038369</td><td>0.0225637668</td><td>1.306061e-02</td><td>4.280413e-02</td><td>0.03776265</td><td>5.620612e-03</td><td>2.203963e-03</td><td>1.479093e-02</td><td>2.010434e-02</td><td>5.407611e-04</td><td>6.411098e-03</td><td>3.753455e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CQ-6227-01A</th><td>0.54102366</td><td>0.2412421894</td><td>1.263138e-01</td><td>2.588085e-03</td><td>0.08882163</td><td>2.847449e-07</td><td>1.274629e-06</td><td>1.352857e-06</td><td>8.880127e-07</td><td>5.012126e-07</td><td>1.886387e-06</td><td>4.404987e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6959-01A</th><td>0.69115943</td><td>0.0868143815</td><td>1.119808e-01</td><td>2.803121e-02</td><td>0.07513598</td><td>5.509745e-04</td><td>5.064183e-06</td><td>2.347650e-03</td><td>5.516346e-06</td><td>3.417677e-07</td><td>1.351226e-05</td><td>3.955105e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-F7-A61V-01A</th><td>0.89525067</td><td>0.0239154964</td><td>5.635728e-02</td><td>3.346720e-06</td><td>0.01864397</td><td>3.553009e-04</td><td>2.959224e-06</td><td>5.670216e-04</td><td>2.310520e-03</td><td>4.332584e-07</td><td>1.550082e-03</td><td>1.042917e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7413-01A</th><td>0.70027072</td><td>0.2378109744</td><td>2.712702e-07</td><td>4.017224e-02</td><td>0.01394333</td><td>3.587617e-05</td><td>1.339581e-06</td><td>6.724798e-03</td><td>8.944177e-04</td><td>1.404934e-04</td><td>3.144350e-06</td><td>2.394474e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7247-01A</th><td>0.66569777</td><td>0.1485187444</td><td>1.370786e-01</td><td>7.200252e-07</td><td>0.04870135</td><td>2.212088e-07</td><td>4.943082e-07</td><td>5.189074e-07</td><td>4.846298e-07</td><td>1.806964e-07</td><td>3.395621e-07</td><td>5.455221e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CR-5249-01A</th><td>0.76454367</td><td>0.0443576958</td><td>4.213912e-07</td><td>6.687471e-02</td><td>0.05448906</td><td>8.501797e-03</td><td>4.055520e-03</td><td>1.371104e-02</td><td>1.656411e-02</td><td>1.112755e-03</td><td>1.360507e-02</td><td>1.218416e-02</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CQ-5331-01A</th><td>0.78235360</td><td>0.0407393114</td><td>2.118289e-07</td><td>1.037272e-01</td><td>0.05794117</td><td>5.733758e-04</td><td>3.486812e-06</td><td>9.742968e-03</td><td>1.747090e-03</td><td>7.207214e-05</td><td>3.096985e-03</td><td>2.579330e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA-BB-8601-01A</th><td>0.97476402</td><td>0.0077573390</td><td>1.299555e-06</td><td>2.344031e-06</td><td>0.01377502</td><td>1.731479e-03</td><td>2.661071e-06</td><td>1.341848e-05</td><td>8.569433e-06</td><td>7.369978e-04</td><td>3.643543e-06</td><td>1.203214e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-A45W-01A</th><td>0.64501228</td><td>0.1003736426</td><td>7.634465e-07</td><td>8.972898e-02</td><td>0.08118746</td><td>5.304755e-02</td><td>4.668449e-06</td><td>9.988465e-03</td><td>8.800786e-03</td><td>7.019862e-04</td><td>6.153426e-03</td><td>4.999988e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CQ-7063-01A</th><td>0.82795833</td><td>0.0157717693</td><td>6.395263e-07</td><td>1.071989e-01</td><td>0.03522953</td><td>1.307273e-06</td><td>5.571277e-06</td><td>9.594590e-03</td><td>9.372649e-04</td><td>6.160940e-04</td><td>2.668512e-03</td><td>1.747479e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-5373-01A</th><td>0.68797000</td><td>0.2299667361</td><td>4.758960e-04</td><td>4.220190e-02</td><td>0.02621258</td><td>6.849174e-05</td><td>1.352270e-05</td><td>1.085064e-02</td><td>4.261388e-06</td><td>4.745499e-04</td><td>1.702080e-03</td><td>5.933012e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-A45T-01A</th><td>0.71773096</td><td>0.0708530723</td><td>3.141035e-02</td><td>9.147216e-02</td><td>0.04497311</td><td>4.805633e-03</td><td>8.073109e-06</td><td>2.740484e-02</td><td>8.359557e-03</td><td>3.344305e-04</td><td>2.609326e-03</td><td>3.848610e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA-HD-A4C1-01A</th><td>0.84885450</td><td>0.1035910946</td><td>4.463907e-07</td><td>5.817188e-03</td><td>0.03405969</td><td>8.387271e-04</td><td>3.536181e-06</td><td>2.643809e-03</td><td>2.087295e-05</td><td>5.490139e-07</td><td>7.022697e-04</td><td>3.467318e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7438-11A</th><td>0.92346829</td><td>0.0107794372</td><td>8.169412e-03</td><td>2.102821e-02</td><td>0.01697486</td><td>1.778206e-03</td><td>9.754485e-05</td><td>9.765350e-03</td><td>1.629515e-03</td><td>3.635568e-04</td><td>4.535285e-03</td><td>1.410328e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-5444-01A</th><td>0.27918413</td><td>0.5265173593</td><td>4.695905e-02</td><td>1.093472e-01</td><td>0.03731843</td><td>6.596345e-07</td><td>1.678087e-06</td><td>7.101029e-05</td><td>1.555470e-05</td><td>7.530197e-07</td><td>5.822362e-04</td><td>1.981863e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA-BA-5556-01A</th><td>0.75529120</td><td>0.0435331604</td><td>2.952937e-07</td><td>1.207894e-01</td><td>0.05357313</td><td>1.173000e-03</td><td>1.222990e-03</td><td>1.506610e-02</td><td>5.626280e-03</td><td>2.814119e-04</td><td>3.438276e-03</td><td>4.800570e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA-P3-A6SX-01A</th><td>0.83130458</td><td>0.1287847942</td><td>1.748934e-02</td><td>8.543231e-07</td><td>0.02133848</td><td>8.273896e-07</td><td>7.626181e-07</td><td>6.959556e-06</td><td>5.326699e-06</td><td>6.660487e-05</td><td>1.528918e-06</td><td>9.999336e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7242-11A</th><td>0.92033599</td><td>0.0167292415</td><td>2.856326e-05</td><td>2.252533e-02</td><td>0.02640606</td><td>1.401460e-04</td><td>6.212577e-06</td><td>5.814562e-03</td><td>1.092367e-03</td><td>2.778300e-04</td><td>4.396532e-03</td><td>2.247169e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-DQ-7592-01A</th><td>0.77657213</td><td>0.1480833868</td><td>2.153864e-02</td><td>1.267932e-02</td><td>0.03047937</td><td>1.026445e-06</td><td>1.200417e-04</td><td>5.320939e-03</td><td>3.126022e-03</td><td>1.418083e-04</td><td>8.122057e-04</td><td>1.125114e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6937-01A</th><td>0.73210512</td><td>0.1790558892</td><td>6.920554e-07</td><td>6.051790e-02</td><td>0.02371145</td><td>1.595918e-06</td><td>6.121839e-06</td><td>7.725410e-06</td><td>1.605688e-03</td><td>8.751306e-05</td><td>2.877875e-03</td><td>2.242220e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA-QK-A8ZB-01A</th><td>0.79596447</td><td>0.1401419183</td><td>4.915362e-07</td><td>8.707466e-03</td><td>0.03265857</td><td>1.130815e-02</td><td>3.749270e-06</td><td>1.149054e-03</td><td>5.090307e-04</td><td>5.001437e-04</td><td>1.466250e-03</td><td>7.590702e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7432-01A</th><td>0.94571467</td><td>0.0278294623</td><td>5.025951e-07</td><td>3.079319e-03</td><td>0.01995220</td><td>5.053822e-07</td><td>4.289658e-06</td><td>1.538838e-04</td><td>9.925769e-04</td><td>1.938185e-04</td><td>3.044177e-04</td><td>1.774354e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7089-01A</th><td>0.91499981</td><td>0.0174213920</td><td>4.626392e-07</td><td>1.222554e-02</td><td>0.04590122</td><td>1.101232e-05</td><td>6.832658e-06</td><td>4.987475e-03</td><td>1.076935e-03</td><td>7.491191e-04</td><td>8.436417e-04</td><td>1.776548e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6939-11A</th><td>0.06391068</td><td>0.0396254273</td><td>8.779284e-01</td><td>2.021104e-07</td><td>0.01853427</td><td>1.534907e-07</td><td>1.507802e-07</td><td>1.420393e-07</td><td>1.391324e-07</td><td>1.071993e-07</td><td>1.602020e-07</td><td>1.505424e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA-BA-4075-01A</th><td>0.87501961</td><td>0.0459568350</td><td>4.980788e-03</td><td>3.187023e-02</td><td>0.02971568</td><td>9.156259e-07</td><td>3.094603e-06</td><td>1.469122e-03</td><td>1.378718e-03</td><td>4.420085e-05</td><td>2.148848e-05</td><td>9.539326e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-T3-A92M-01A</th><td>0.54021403</td><td>0.3363094290</td><td>4.086668e-07</td><td>7.850835e-02</td><td>0.02452715</td><td>5.053911e-03</td><td>4.321249e-06</td><td>4.535910e-03</td><td>6.457165e-03</td><td>2.093600e-04</td><td>7.437517e-04</td><td>3.436222e-03</td></tr>\n",
       "\t<tr><th scope=row>⋮</th><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7430-01A</th><td>0.9522944</td><td>0.021582735</td><td>7.895697e-07</td><td>5.593641e-04</td><td>0.0220002455</td><td>2.510364e-05</td><td>3.829535e-06</td><td>9.251480e-04</td><td>6.417269e-06</td><td>1.467724e-04</td><td>2.901787e-05</td><td>2.426159e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-D6-A74Q-01A</th><td>0.8145015</td><td>0.112548057</td><td>8.259003e-07</td><td>3.924812e-03</td><td>0.0272028640</td><td>7.791500e-03</td><td>3.423638e-05</td><td>3.396870e-03</td><td>8.751835e-03</td><td>3.830402e-03</td><td>5.718750e-03</td><td>1.229835e-02</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7255-01A</th><td>0.9085115</td><td>0.029518875</td><td>1.604425e-02</td><td>7.154988e-07</td><td>0.0437404879</td><td>1.095024e-06</td><td>6.808349e-07</td><td>1.552601e-04</td><td>5.681043e-04</td><td>2.181712e-05</td><td>4.695111e-07</td><td>1.436786e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CQ-6223-01A</th><td>0.9457482</td><td>0.018397980</td><td>3.876277e-07</td><td>1.391535e-02</td><td>0.0106591300</td><td>8.026109e-04</td><td>3.619042e-05</td><td>4.574028e-03</td><td>8.657860e-04</td><td>8.635799e-04</td><td>1.685840e-03</td><td>2.450946e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-A460-01A</th><td>0.6303024</td><td>0.164898903</td><td>6.629139e-07</td><td>6.736238e-02</td><td>0.0735747653</td><td>6.520934e-03</td><td>2.105745e-02</td><td>1.550624e-02</td><td>6.425260e-03</td><td>6.974457e-04</td><td>6.324749e-03</td><td>7.328822e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7261-01A</th><td>0.6848085</td><td>0.222022093</td><td>1.024530e-06</td><td>2.907047e-02</td><td>0.0515304559</td><td>4.028455e-03</td><td>7.093352e-06</td><td>1.264518e-03</td><td>7.358057e-06</td><td>4.046752e-04</td><td>2.081536e-04</td><td>6.647187e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-4736-01A</th><td>0.4435007</td><td>0.203851719</td><td>1.835070e-01</td><td>1.121733e-01</td><td>0.0493733818</td><td>3.042112e-07</td><td>5.745673e-04</td><td>4.504487e-03</td><td>2.201801e-03</td><td>2.797655e-07</td><td>3.094837e-04</td><td>2.977295e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CR-7404-01A</th><td>0.7707652</td><td>0.050124414</td><td>6.147691e-07</td><td>6.723222e-02</td><td>0.0644535513</td><td>8.109896e-03</td><td>1.245529e-03</td><td>1.678593e-02</td><td>4.956443e-03</td><td>7.647812e-04</td><td>9.602612e-03</td><td>5.958792e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-UF-A719-01A</th><td>0.9247836</td><td>0.024351152</td><td>9.032943e-05</td><td>3.394154e-03</td><td>0.0356415653</td><td>4.339135e-04</td><td>6.728553e-05</td><td>4.072791e-03</td><td>2.117762e-03</td><td>3.964999e-05</td><td>9.811350e-04</td><td>4.026614e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7236-01A</th><td>0.6923188</td><td>0.196991255</td><td>5.414749e-07</td><td>2.256574e-02</td><td>0.0749498741</td><td>2.022737e-04</td><td>1.901099e-06</td><td>1.387850e-05</td><td>1.457108e-03</td><td>1.077066e-04</td><td>5.148918e-04</td><td>1.087603e-02</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6951-01A</th><td>0.8573459</td><td>0.080220851</td><td>4.729976e-02</td><td>1.689773e-03</td><td>0.0125731713</td><td>6.263061e-07</td><td>1.552862e-06</td><td>5.196739e-06</td><td>3.337689e-06</td><td>6.550422e-04</td><td>7.414515e-05</td><td>1.306809e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-4728-01A</th><td>0.2144844</td><td>0.580468135</td><td>8.110333e-03</td><td>1.493368e-01</td><td>0.0409370445</td><td>6.582277e-04</td><td>3.371294e-06</td><td>4.450652e-03</td><td>8.723386e-06</td><td>4.704836e-04</td><td>1.053649e-03</td><td>1.817814e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7090-01A</th><td>0.6009539</td><td>0.249057663</td><td>2.993599e-07</td><td>6.615897e-02</td><td>0.0689356737</td><td>1.220777e-06</td><td>1.710834e-06</td><td>9.923544e-03</td><td>9.706727e-05</td><td>2.877527e-04</td><td>7.086549e-05</td><td>4.511355e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-5979-01A</th><td>0.8908949</td><td>0.055552577</td><td>1.539655e-03</td><td>8.153458e-03</td><td>0.0366240069</td><td>5.814996e-07</td><td>2.301133e-06</td><td>7.191630e-03</td><td>6.528483e-06</td><td>2.030841e-05</td><td>1.451474e-06</td><td>1.265226e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CQ-7069-01A</th><td>0.8278284</td><td>0.092959285</td><td>4.770939e-07</td><td>4.438142e-04</td><td>0.0685432957</td><td>1.175565e-06</td><td>2.642127e-06</td><td>8.358562e-03</td><td>3.649764e-06</td><td>2.885009e-04</td><td>1.919992e-05</td><td>1.551036e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-4733-01A</th><td>0.3456848</td><td>0.285705707</td><td>1.686708e-02</td><td>1.685431e-01</td><td>0.0972987967</td><td>1.683155e-02</td><td>3.003044e-05</td><td>3.209453e-02</td><td>8.573240e-03</td><td>1.672578e-03</td><td>2.323855e-02</td><td>3.460009e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CR-7390-01A</th><td>0.7451947</td><td>0.213920663</td><td>4.301343e-07</td><td>5.872467e-03</td><td>0.0303656461</td><td>2.065906e-05</td><td>1.787416e-06</td><td>7.774182e-06</td><td>2.897329e-06</td><td>1.662505e-04</td><td>1.206895e-06</td><td>4.445526e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-A45X-01A</th><td>0.9493245</td><td>0.020004646</td><td>1.110329e-06</td><td>5.965875e-03</td><td>0.0168099053</td><td>4.567125e-05</td><td>6.166679e-06</td><td>1.847638e-03</td><td>2.337816e-03</td><td>6.785496e-05</td><td>7.777258e-04</td><td>2.811138e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-IQ-A6SH-01A</th><td>0.8961116</td><td>0.036440188</td><td>6.732549e-07</td><td>2.994372e-02</td><td>0.0275554746</td><td>9.626654e-04</td><td>2.418314e-05</td><td>7.269247e-03</td><td>4.617974e-04</td><td>3.226413e-04</td><td>6.891492e-04</td><td>2.186796e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6962-11A</th><td>0.9204774</td><td>0.037895283</td><td>1.048223e-04</td><td>4.559363e-03</td><td>0.0287513385</td><td>7.001844e-04</td><td>2.465428e-06</td><td>2.058588e-03</td><td>8.891491e-04</td><td>4.198810e-04</td><td>2.243572e-03</td><td>1.897996e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6960-11A</th><td>0.9469077</td><td>0.011001313</td><td>9.216748e-05</td><td>1.009368e-02</td><td>0.0269575408</td><td>2.643422e-05</td><td>3.702759e-06</td><td>1.202062e-03</td><td>1.391011e-05</td><td>8.802926e-04</td><td>1.712646e-03</td><td>1.108602e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-A464-01A</th><td>0.4956189</td><td>0.365218102</td><td>7.221133e-02</td><td>1.037947e-02</td><td>0.0492785176</td><td>4.868739e-07</td><td>3.738478e-06</td><td>4.140700e-03</td><td>5.425213e-04</td><td>8.347710e-05</td><td>2.516128e-03</td><td>6.623413e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA-C9-A47Z-01A</th><td>0.9618175</td><td>0.012865199</td><td>6.463346e-03</td><td>2.924776e-03</td><td>0.0127283062</td><td>1.794621e-05</td><td>2.189491e-05</td><td>1.659820e-03</td><td>1.646568e-04</td><td>2.586389e-05</td><td>1.264258e-04</td><td>1.184250e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-6010-01A</th><td>0.7090638</td><td>0.092435372</td><td>1.907857e-02</td><td>1.028982e-01</td><td>0.0686872297</td><td>6.985689e-03</td><td>1.609571e-06</td><td>2.066856e-05</td><td>4.058772e-06</td><td>8.159275e-04</td><td>1.319148e-06</td><td>7.523645e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA-WA-A7GZ-11A</th><td>0.2250252</td><td>0.011840187</td><td>7.626023e-01</td><td>2.209323e-07</td><td>0.0005308816</td><td>1.593409e-07</td><td>1.963554e-07</td><td>1.654410e-07</td><td>1.732265e-07</td><td>1.398135e-07</td><td>2.031713e-07</td><td>1.826388e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7235-01A</th><td>0.5571721</td><td>0.331035588</td><td>2.944636e-07</td><td>4.341405e-02</td><td>0.0517575839</td><td>3.909553e-07</td><td>6.524707e-04</td><td>1.192152e-02</td><td>1.210964e-03</td><td>3.739575e-04</td><td>7.400603e-04</td><td>1.721061e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CX-7086-01A</th><td>0.9359061</td><td>0.013663174</td><td>1.266288e-06</td><td>5.613298e-03</td><td>0.0325342298</td><td>1.092963e-03</td><td>5.436330e-04</td><td>5.968087e-03</td><td>1.168945e-05</td><td>6.030335e-05</td><td>2.253336e-03</td><td>2.351940e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6935-11A</th><td>0.9228189</td><td>0.009082117</td><td>6.677475e-04</td><td>3.730673e-02</td><td>0.0272978745</td><td>3.001992e-04</td><td>1.349548e-06</td><td>1.229702e-03</td><td>2.754238e-04</td><td>4.052511e-04</td><td>2.227567e-05</td><td>5.923958e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA-P3-A6SW-01A</th><td>0.7411353</td><td>0.087745865</td><td>7.265310e-07</td><td>4.834572e-02</td><td>0.0502441143</td><td>2.081898e-02</td><td>1.012480e-03</td><td>1.718169e-02</td><td>1.708835e-02</td><td>2.908469e-03</td><td>1.350914e-02</td><td>9.189827e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA-HD-A6HZ-01A</th><td>0.6657255</td><td>0.117164007</td><td>6.468833e-02</td><td>5.056453e-02</td><td>0.0618777771</td><td>8.469815e-03</td><td>1.001852e-02</td><td>4.467721e-03</td><td>7.463512e-03</td><td>3.987480e-04</td><td>2.939265e-03</td><td>6.222276e-03</td></tr>\n",
       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "A matrix: 546 × 12 of type dbl\n",
       "\\begin{tabular}{r|llllllllllll}\n",
       "  & tumor & Fibroblast & tconv.cells & Macrophage & Endothelial & b.cells & cd14.cells & cd8.cells & treg.cells & mast.cells & pdc.cells & nk.cells\\\\\n",
       "\\hline\n",
       "\tTCGA-BB-4224-01A & 0.92733662 & 0.0190890154 & 6.065475e-03 & 1.667066e-02 & 0.01899481 & 7.521237e-07 & 2.923092e-05 & 5.354050e-03 & 3.046525e-04 & 1.783831e-04 & 1.032630e-03 & 4.943720e-03\\\\\n",
       "\tTCGA-H7-7774-01A & 0.96023355 & 0.0005243755 & 5.746715e-07 & 1.726243e-02 & 0.01281692 & 2.474022e-04 & 1.642298e-05 & 6.565494e-03 & 7.144899e-04 & 5.097020e-04 & 1.077549e-03 & 3.108857e-05\\\\\n",
       "\tTCGA-CV-6943-01A & 0.42282326 & 0.3809782307 & 2.688987e-07 & 1.322473e-01 & 0.03871532 & 3.798463e-03 & 4.150265e-06 & 1.605742e-02 & 1.883073e-03 & 7.728221e-04 & 2.718970e-03 & 7.299435e-07\\\\\n",
       "\tTCGA-CN-5374-01A & 0.83038369 & 0.0225637668 & 1.306061e-02 & 4.280413e-02 & 0.03776265 & 5.620612e-03 & 2.203963e-03 & 1.479093e-02 & 2.010434e-02 & 5.407611e-04 & 6.411098e-03 & 3.753455e-03\\\\\n",
       "\tTCGA-CQ-6227-01A & 0.54102366 & 0.2412421894 & 1.263138e-01 & 2.588085e-03 & 0.08882163 & 2.847449e-07 & 1.274629e-06 & 1.352857e-06 & 8.880127e-07 & 5.012126e-07 & 1.886387e-06 & 4.404987e-06\\\\\n",
       "\tTCGA-CV-6959-01A & 0.69115943 & 0.0868143815 & 1.119808e-01 & 2.803121e-02 & 0.07513598 & 5.509745e-04 & 5.064183e-06 & 2.347650e-03 & 5.516346e-06 & 3.417677e-07 & 1.351226e-05 & 3.955105e-03\\\\\n",
       "\tTCGA-F7-A61V-01A & 0.89525067 & 0.0239154964 & 5.635728e-02 & 3.346720e-06 & 0.01864397 & 3.553009e-04 & 2.959224e-06 & 5.670216e-04 & 2.310520e-03 & 4.332584e-07 & 1.550082e-03 & 1.042917e-03\\\\\n",
       "\tTCGA-CV-7413-01A & 0.70027072 & 0.2378109744 & 2.712702e-07 & 4.017224e-02 & 0.01394333 & 3.587617e-05 & 1.339581e-06 & 6.724798e-03 & 8.944177e-04 & 1.404934e-04 & 3.144350e-06 & 2.394474e-06\\\\\n",
       "\tTCGA-CV-7247-01A & 0.66569777 & 0.1485187444 & 1.370786e-01 & 7.200252e-07 & 0.04870135 & 2.212088e-07 & 4.943082e-07 & 5.189074e-07 & 4.846298e-07 & 1.806964e-07 & 3.395621e-07 & 5.455221e-07\\\\\n",
       "\tTCGA-CR-5249-01A & 0.76454367 & 0.0443576958 & 4.213912e-07 & 6.687471e-02 & 0.05448906 & 8.501797e-03 & 4.055520e-03 & 1.371104e-02 & 1.656411e-02 & 1.112755e-03 & 1.360507e-02 & 1.218416e-02\\\\\n",
       "\tTCGA-CQ-5331-01A & 0.78235360 & 0.0407393114 & 2.118289e-07 & 1.037272e-01 & 0.05794117 & 5.733758e-04 & 3.486812e-06 & 9.742968e-03 & 1.747090e-03 & 7.207214e-05 & 3.096985e-03 & 2.579330e-06\\\\\n",
       "\tTCGA-BB-8601-01A & 0.97476402 & 0.0077573390 & 1.299555e-06 & 2.344031e-06 & 0.01377502 & 1.731479e-03 & 2.661071e-06 & 1.341848e-05 & 8.569433e-06 & 7.369978e-04 & 3.643543e-06 & 1.203214e-03\\\\\n",
       "\tTCGA-CV-A45W-01A & 0.64501228 & 0.1003736426 & 7.634465e-07 & 8.972898e-02 & 0.08118746 & 5.304755e-02 & 4.668449e-06 & 9.988465e-03 & 8.800786e-03 & 7.019862e-04 & 6.153426e-03 & 4.999988e-03\\\\\n",
       "\tTCGA-CQ-7063-01A & 0.82795833 & 0.0157717693 & 6.395263e-07 & 1.071989e-01 & 0.03522953 & 1.307273e-06 & 5.571277e-06 & 9.594590e-03 & 9.372649e-04 & 6.160940e-04 & 2.668512e-03 & 1.747479e-05\\\\\n",
       "\tTCGA-CN-5373-01A & 0.68797000 & 0.2299667361 & 4.758960e-04 & 4.220190e-02 & 0.02621258 & 6.849174e-05 & 1.352270e-05 & 1.085064e-02 & 4.261388e-06 & 4.745499e-04 & 1.702080e-03 & 5.933012e-05\\\\\n",
       "\tTCGA-CV-A45T-01A & 0.71773096 & 0.0708530723 & 3.141035e-02 & 9.147216e-02 & 0.04497311 & 4.805633e-03 & 8.073109e-06 & 2.740484e-02 & 8.359557e-03 & 3.344305e-04 & 2.609326e-03 & 3.848610e-05\\\\\n",
       "\tTCGA-HD-A4C1-01A & 0.84885450 & 0.1035910946 & 4.463907e-07 & 5.817188e-03 & 0.03405969 & 8.387271e-04 & 3.536181e-06 & 2.643809e-03 & 2.087295e-05 & 5.490139e-07 & 7.022697e-04 & 3.467318e-03\\\\\n",
       "\tTCGA-CV-7438-11A & 0.92346829 & 0.0107794372 & 8.169412e-03 & 2.102821e-02 & 0.01697486 & 1.778206e-03 & 9.754485e-05 & 9.765350e-03 & 1.629515e-03 & 3.635568e-04 & 4.535285e-03 & 1.410328e-03\\\\\n",
       "\tTCGA-CV-5444-01A & 0.27918413 & 0.5265173593 & 4.695905e-02 & 1.093472e-01 & 0.03731843 & 6.596345e-07 & 1.678087e-06 & 7.101029e-05 & 1.555470e-05 & 7.530197e-07 & 5.822362e-04 & 1.981863e-06\\\\\n",
       "\tTCGA-BA-5556-01A & 0.75529120 & 0.0435331604 & 2.952937e-07 & 1.207894e-01 & 0.05357313 & 1.173000e-03 & 1.222990e-03 & 1.506610e-02 & 5.626280e-03 & 2.814119e-04 & 3.438276e-03 & 4.800570e-06\\\\\n",
       "\tTCGA-P3-A6SX-01A & 0.83130458 & 0.1287847942 & 1.748934e-02 & 8.543231e-07 & 0.02133848 & 8.273896e-07 & 7.626181e-07 & 6.959556e-06 & 5.326699e-06 & 6.660487e-05 & 1.528918e-06 & 9.999336e-04\\\\\n",
       "\tTCGA-CV-7242-11A & 0.92033599 & 0.0167292415 & 2.856326e-05 & 2.252533e-02 & 0.02640606 & 1.401460e-04 & 6.212577e-06 & 5.814562e-03 & 1.092367e-03 & 2.778300e-04 & 4.396532e-03 & 2.247169e-03\\\\\n",
       "\tTCGA-DQ-7592-01A & 0.77657213 & 0.1480833868 & 2.153864e-02 & 1.267932e-02 & 0.03047937 & 1.026445e-06 & 1.200417e-04 & 5.320939e-03 & 3.126022e-03 & 1.418083e-04 & 8.122057e-04 & 1.125114e-03\\\\\n",
       "\tTCGA-CV-6937-01A & 0.73210512 & 0.1790558892 & 6.920554e-07 & 6.051790e-02 & 0.02371145 & 1.595918e-06 & 6.121839e-06 & 7.725410e-06 & 1.605688e-03 & 8.751306e-05 & 2.877875e-03 & 2.242220e-05\\\\\n",
       "\tTCGA-QK-A8ZB-01A & 0.79596447 & 0.1401419183 & 4.915362e-07 & 8.707466e-03 & 0.03265857 & 1.130815e-02 & 3.749270e-06 & 1.149054e-03 & 5.090307e-04 & 5.001437e-04 & 1.466250e-03 & 7.590702e-03\\\\\n",
       "\tTCGA-CV-7432-01A & 0.94571467 & 0.0278294623 & 5.025951e-07 & 3.079319e-03 & 0.01995220 & 5.053822e-07 & 4.289658e-06 & 1.538838e-04 & 9.925769e-04 & 1.938185e-04 & 3.044177e-04 & 1.774354e-03\\\\\n",
       "\tTCGA-CV-7089-01A & 0.91499981 & 0.0174213920 & 4.626392e-07 & 1.222554e-02 & 0.04590122 & 1.101232e-05 & 6.832658e-06 & 4.987475e-03 & 1.076935e-03 & 7.491191e-04 & 8.436417e-04 & 1.776548e-03\\\\\n",
       "\tTCGA-CV-6939-11A & 0.06391068 & 0.0396254273 & 8.779284e-01 & 2.021104e-07 & 0.01853427 & 1.534907e-07 & 1.507802e-07 & 1.420393e-07 & 1.391324e-07 & 1.071993e-07 & 1.602020e-07 & 1.505424e-07\\\\\n",
       "\tTCGA-BA-4075-01A & 0.87501961 & 0.0459568350 & 4.980788e-03 & 3.187023e-02 & 0.02971568 & 9.156259e-07 & 3.094603e-06 & 1.469122e-03 & 1.378718e-03 & 4.420085e-05 & 2.148848e-05 & 9.539326e-03\\\\\n",
       "\tTCGA-T3-A92M-01A & 0.54021403 & 0.3363094290 & 4.086668e-07 & 7.850835e-02 & 0.02452715 & 5.053911e-03 & 4.321249e-06 & 4.535910e-03 & 6.457165e-03 & 2.093600e-04 & 7.437517e-04 & 3.436222e-03\\\\\n",
       "\t⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮\\\\\n",
       "\tTCGA-CV-7430-01A & 0.9522944 & 0.021582735 & 7.895697e-07 & 5.593641e-04 & 0.0220002455 & 2.510364e-05 & 3.829535e-06 & 9.251480e-04 & 6.417269e-06 & 1.467724e-04 & 2.901787e-05 & 2.426159e-03\\\\\n",
       "\tTCGA-D6-A74Q-01A & 0.8145015 & 0.112548057 & 8.259003e-07 & 3.924812e-03 & 0.0272028640 & 7.791500e-03 & 3.423638e-05 & 3.396870e-03 & 8.751835e-03 & 3.830402e-03 & 5.718750e-03 & 1.229835e-02\\\\\n",
       "\tTCGA-CV-7255-01A & 0.9085115 & 0.029518875 & 1.604425e-02 & 7.154988e-07 & 0.0437404879 & 1.095024e-06 & 6.808349e-07 & 1.552601e-04 & 5.681043e-04 & 2.181712e-05 & 4.695111e-07 & 1.436786e-03\\\\\n",
       "\tTCGA-CQ-6223-01A & 0.9457482 & 0.018397980 & 3.876277e-07 & 1.391535e-02 & 0.0106591300 & 8.026109e-04 & 3.619042e-05 & 4.574028e-03 & 8.657860e-04 & 8.635799e-04 & 1.685840e-03 & 2.450946e-03\\\\\n",
       "\tTCGA-CV-A460-01A & 0.6303024 & 0.164898903 & 6.629139e-07 & 6.736238e-02 & 0.0735747653 & 6.520934e-03 & 2.105745e-02 & 1.550624e-02 & 6.425260e-03 & 6.974457e-04 & 6.324749e-03 & 7.328822e-03\\\\\n",
       "\tTCGA-CV-7261-01A & 0.6848085 & 0.222022093 & 1.024530e-06 & 2.907047e-02 & 0.0515304559 & 4.028455e-03 & 7.093352e-06 & 1.264518e-03 & 7.358057e-06 & 4.046752e-04 & 2.081536e-04 & 6.647187e-03\\\\\n",
       "\tTCGA-CN-4736-01A & 0.4435007 & 0.203851719 & 1.835070e-01 & 1.121733e-01 & 0.0493733818 & 3.042112e-07 & 5.745673e-04 & 4.504487e-03 & 2.201801e-03 & 2.797655e-07 & 3.094837e-04 & 2.977295e-06\\\\\n",
       "\tTCGA-CR-7404-01A & 0.7707652 & 0.050124414 & 6.147691e-07 & 6.723222e-02 & 0.0644535513 & 8.109896e-03 & 1.245529e-03 & 1.678593e-02 & 4.956443e-03 & 7.647812e-04 & 9.602612e-03 & 5.958792e-03\\\\\n",
       "\tTCGA-UF-A719-01A & 0.9247836 & 0.024351152 & 9.032943e-05 & 3.394154e-03 & 0.0356415653 & 4.339135e-04 & 6.728553e-05 & 4.072791e-03 & 2.117762e-03 & 3.964999e-05 & 9.811350e-04 & 4.026614e-03\\\\\n",
       "\tTCGA-CV-7236-01A & 0.6923188 & 0.196991255 & 5.414749e-07 & 2.256574e-02 & 0.0749498741 & 2.022737e-04 & 1.901099e-06 & 1.387850e-05 & 1.457108e-03 & 1.077066e-04 & 5.148918e-04 & 1.087603e-02\\\\\n",
       "\tTCGA-CV-6951-01A & 0.8573459 & 0.080220851 & 4.729976e-02 & 1.689773e-03 & 0.0125731713 & 6.263061e-07 & 1.552862e-06 & 5.196739e-06 & 3.337689e-06 & 6.550422e-04 & 7.414515e-05 & 1.306809e-04\\\\\n",
       "\tTCGA-CN-4728-01A & 0.2144844 & 0.580468135 & 8.110333e-03 & 1.493368e-01 & 0.0409370445 & 6.582277e-04 & 3.371294e-06 & 4.450652e-03 & 8.723386e-06 & 4.704836e-04 & 1.053649e-03 & 1.817814e-05\\\\\n",
       "\tTCGA-CV-7090-01A & 0.6009539 & 0.249057663 & 2.993599e-07 & 6.615897e-02 & 0.0689356737 & 1.220777e-06 & 1.710834e-06 & 9.923544e-03 & 9.706727e-05 & 2.877527e-04 & 7.086549e-05 & 4.511355e-03\\\\\n",
       "\tTCGA-CV-5979-01A & 0.8908949 & 0.055552577 & 1.539655e-03 & 8.153458e-03 & 0.0366240069 & 5.814996e-07 & 2.301133e-06 & 7.191630e-03 & 6.528483e-06 & 2.030841e-05 & 1.451474e-06 & 1.265226e-05\\\\\n",
       "\tTCGA-CQ-7069-01A & 0.8278284 & 0.092959285 & 4.770939e-07 & 4.438142e-04 & 0.0685432957 & 1.175565e-06 & 2.642127e-06 & 8.358562e-03 & 3.649764e-06 & 2.885009e-04 & 1.919992e-05 & 1.551036e-03\\\\\n",
       "\tTCGA-CN-4733-01A & 0.3456848 & 0.285705707 & 1.686708e-02 & 1.685431e-01 & 0.0972987967 & 1.683155e-02 & 3.003044e-05 & 3.209453e-02 & 8.573240e-03 & 1.672578e-03 & 2.323855e-02 & 3.460009e-03\\\\\n",
       "\tTCGA-CR-7390-01A & 0.7451947 & 0.213920663 & 4.301343e-07 & 5.872467e-03 & 0.0303656461 & 2.065906e-05 & 1.787416e-06 & 7.774182e-06 & 2.897329e-06 & 1.662505e-04 & 1.206895e-06 & 4.445526e-03\\\\\n",
       "\tTCGA-CV-A45X-01A & 0.9493245 & 0.020004646 & 1.110329e-06 & 5.965875e-03 & 0.0168099053 & 4.567125e-05 & 6.166679e-06 & 1.847638e-03 & 2.337816e-03 & 6.785496e-05 & 7.777258e-04 & 2.811138e-03\\\\\n",
       "\tTCGA-IQ-A6SH-01A & 0.8961116 & 0.036440188 & 6.732549e-07 & 2.994372e-02 & 0.0275554746 & 9.626654e-04 & 2.418314e-05 & 7.269247e-03 & 4.617974e-04 & 3.226413e-04 & 6.891492e-04 & 2.186796e-04\\\\\n",
       "\tTCGA-CV-6962-11A & 0.9204774 & 0.037895283 & 1.048223e-04 & 4.559363e-03 & 0.0287513385 & 7.001844e-04 & 2.465428e-06 & 2.058588e-03 & 8.891491e-04 & 4.198810e-04 & 2.243572e-03 & 1.897996e-03\\\\\n",
       "\tTCGA-CV-6960-11A & 0.9469077 & 0.011001313 & 9.216748e-05 & 1.009368e-02 & 0.0269575408 & 2.643422e-05 & 3.702759e-06 & 1.202062e-03 & 1.391011e-05 & 8.802926e-04 & 1.712646e-03 & 1.108602e-03\\\\\n",
       "\tTCGA-CV-A464-01A & 0.4956189 & 0.365218102 & 7.221133e-02 & 1.037947e-02 & 0.0492785176 & 4.868739e-07 & 3.738478e-06 & 4.140700e-03 & 5.425213e-04 & 8.347710e-05 & 2.516128e-03 & 6.623413e-06\\\\\n",
       "\tTCGA-C9-A47Z-01A & 0.9618175 & 0.012865199 & 6.463346e-03 & 2.924776e-03 & 0.0127283062 & 1.794621e-05 & 2.189491e-05 & 1.659820e-03 & 1.646568e-04 & 2.586389e-05 & 1.264258e-04 & 1.184250e-03\\\\\n",
       "\tTCGA-CN-6010-01A & 0.7090638 & 0.092435372 & 1.907857e-02 & 1.028982e-01 & 0.0686872297 & 6.985689e-03 & 1.609571e-06 & 2.066856e-05 & 4.058772e-06 & 8.159275e-04 & 1.319148e-06 & 7.523645e-06\\\\\n",
       "\tTCGA-WA-A7GZ-11A & 0.2250252 & 0.011840187 & 7.626023e-01 & 2.209323e-07 & 0.0005308816 & 1.593409e-07 & 1.963554e-07 & 1.654410e-07 & 1.732265e-07 & 1.398135e-07 & 2.031713e-07 & 1.826388e-07\\\\\n",
       "\tTCGA-CV-7235-01A & 0.5571721 & 0.331035588 & 2.944636e-07 & 4.341405e-02 & 0.0517575839 & 3.909553e-07 & 6.524707e-04 & 1.192152e-02 & 1.210964e-03 & 3.739575e-04 & 7.400603e-04 & 1.721061e-03\\\\\n",
       "\tTCGA-CX-7086-01A & 0.9359061 & 0.013663174 & 1.266288e-06 & 5.613298e-03 & 0.0325342298 & 1.092963e-03 & 5.436330e-04 & 5.968087e-03 & 1.168945e-05 & 6.030335e-05 & 2.253336e-03 & 2.351940e-03\\\\\n",
       "\tTCGA-CV-6935-11A & 0.9228189 & 0.009082117 & 6.677475e-04 & 3.730673e-02 & 0.0272978745 & 3.001992e-04 & 1.349548e-06 & 1.229702e-03 & 2.754238e-04 & 4.052511e-04 & 2.227567e-05 & 5.923958e-04\\\\\n",
       "\tTCGA-P3-A6SW-01A & 0.7411353 & 0.087745865 & 7.265310e-07 & 4.834572e-02 & 0.0502441143 & 2.081898e-02 & 1.012480e-03 & 1.718169e-02 & 1.708835e-02 & 2.908469e-03 & 1.350914e-02 & 9.189827e-06\\\\\n",
       "\tTCGA-HD-A6HZ-01A & 0.6657255 & 0.117164007 & 6.468833e-02 & 5.056453e-02 & 0.0618777771 & 8.469815e-03 & 1.001852e-02 & 4.467721e-03 & 7.463512e-03 & 3.987480e-04 & 2.939265e-03 & 6.222276e-03\\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "A matrix: 546 × 12 of type dbl\n",
       "\n",
       "| <!--/--> | tumor | Fibroblast | tconv.cells | Macrophage | Endothelial | b.cells | cd14.cells | cd8.cells | treg.cells | mast.cells | pdc.cells | nk.cells |\n",
       "|---|---|---|---|---|---|---|---|---|---|---|---|---|\n",
       "| TCGA-BB-4224-01A | 0.92733662 | 0.0190890154 | 6.065475e-03 | 1.667066e-02 | 0.01899481 | 7.521237e-07 | 2.923092e-05 | 5.354050e-03 | 3.046525e-04 | 1.783831e-04 | 1.032630e-03 | 4.943720e-03 |\n",
       "| TCGA-H7-7774-01A | 0.96023355 | 0.0005243755 | 5.746715e-07 | 1.726243e-02 | 0.01281692 | 2.474022e-04 | 1.642298e-05 | 6.565494e-03 | 7.144899e-04 | 5.097020e-04 | 1.077549e-03 | 3.108857e-05 |\n",
       "| TCGA-CV-6943-01A | 0.42282326 | 0.3809782307 | 2.688987e-07 | 1.322473e-01 | 0.03871532 | 3.798463e-03 | 4.150265e-06 | 1.605742e-02 | 1.883073e-03 | 7.728221e-04 | 2.718970e-03 | 7.299435e-07 |\n",
       "| TCGA-CN-5374-01A | 0.83038369 | 0.0225637668 | 1.306061e-02 | 4.280413e-02 | 0.03776265 | 5.620612e-03 | 2.203963e-03 | 1.479093e-02 | 2.010434e-02 | 5.407611e-04 | 6.411098e-03 | 3.753455e-03 |\n",
       "| TCGA-CQ-6227-01A | 0.54102366 | 0.2412421894 | 1.263138e-01 | 2.588085e-03 | 0.08882163 | 2.847449e-07 | 1.274629e-06 | 1.352857e-06 | 8.880127e-07 | 5.012126e-07 | 1.886387e-06 | 4.404987e-06 |\n",
       "| TCGA-CV-6959-01A | 0.69115943 | 0.0868143815 | 1.119808e-01 | 2.803121e-02 | 0.07513598 | 5.509745e-04 | 5.064183e-06 | 2.347650e-03 | 5.516346e-06 | 3.417677e-07 | 1.351226e-05 | 3.955105e-03 |\n",
       "| TCGA-F7-A61V-01A | 0.89525067 | 0.0239154964 | 5.635728e-02 | 3.346720e-06 | 0.01864397 | 3.553009e-04 | 2.959224e-06 | 5.670216e-04 | 2.310520e-03 | 4.332584e-07 | 1.550082e-03 | 1.042917e-03 |\n",
       "| TCGA-CV-7413-01A | 0.70027072 | 0.2378109744 | 2.712702e-07 | 4.017224e-02 | 0.01394333 | 3.587617e-05 | 1.339581e-06 | 6.724798e-03 | 8.944177e-04 | 1.404934e-04 | 3.144350e-06 | 2.394474e-06 |\n",
       "| TCGA-CV-7247-01A | 0.66569777 | 0.1485187444 | 1.370786e-01 | 7.200252e-07 | 0.04870135 | 2.212088e-07 | 4.943082e-07 | 5.189074e-07 | 4.846298e-07 | 1.806964e-07 | 3.395621e-07 | 5.455221e-07 |\n",
       "| TCGA-CR-5249-01A | 0.76454367 | 0.0443576958 | 4.213912e-07 | 6.687471e-02 | 0.05448906 | 8.501797e-03 | 4.055520e-03 | 1.371104e-02 | 1.656411e-02 | 1.112755e-03 | 1.360507e-02 | 1.218416e-02 |\n",
       "| TCGA-CQ-5331-01A | 0.78235360 | 0.0407393114 | 2.118289e-07 | 1.037272e-01 | 0.05794117 | 5.733758e-04 | 3.486812e-06 | 9.742968e-03 | 1.747090e-03 | 7.207214e-05 | 3.096985e-03 | 2.579330e-06 |\n",
       "| TCGA-BB-8601-01A | 0.97476402 | 0.0077573390 | 1.299555e-06 | 2.344031e-06 | 0.01377502 | 1.731479e-03 | 2.661071e-06 | 1.341848e-05 | 8.569433e-06 | 7.369978e-04 | 3.643543e-06 | 1.203214e-03 |\n",
       "| TCGA-CV-A45W-01A | 0.64501228 | 0.1003736426 | 7.634465e-07 | 8.972898e-02 | 0.08118746 | 5.304755e-02 | 4.668449e-06 | 9.988465e-03 | 8.800786e-03 | 7.019862e-04 | 6.153426e-03 | 4.999988e-03 |\n",
       "| TCGA-CQ-7063-01A | 0.82795833 | 0.0157717693 | 6.395263e-07 | 1.071989e-01 | 0.03522953 | 1.307273e-06 | 5.571277e-06 | 9.594590e-03 | 9.372649e-04 | 6.160940e-04 | 2.668512e-03 | 1.747479e-05 |\n",
       "| TCGA-CN-5373-01A | 0.68797000 | 0.2299667361 | 4.758960e-04 | 4.220190e-02 | 0.02621258 | 6.849174e-05 | 1.352270e-05 | 1.085064e-02 | 4.261388e-06 | 4.745499e-04 | 1.702080e-03 | 5.933012e-05 |\n",
       "| TCGA-CV-A45T-01A | 0.71773096 | 0.0708530723 | 3.141035e-02 | 9.147216e-02 | 0.04497311 | 4.805633e-03 | 8.073109e-06 | 2.740484e-02 | 8.359557e-03 | 3.344305e-04 | 2.609326e-03 | 3.848610e-05 |\n",
       "| TCGA-HD-A4C1-01A | 0.84885450 | 0.1035910946 | 4.463907e-07 | 5.817188e-03 | 0.03405969 | 8.387271e-04 | 3.536181e-06 | 2.643809e-03 | 2.087295e-05 | 5.490139e-07 | 7.022697e-04 | 3.467318e-03 |\n",
       "| TCGA-CV-7438-11A | 0.92346829 | 0.0107794372 | 8.169412e-03 | 2.102821e-02 | 0.01697486 | 1.778206e-03 | 9.754485e-05 | 9.765350e-03 | 1.629515e-03 | 3.635568e-04 | 4.535285e-03 | 1.410328e-03 |\n",
       "| TCGA-CV-5444-01A | 0.27918413 | 0.5265173593 | 4.695905e-02 | 1.093472e-01 | 0.03731843 | 6.596345e-07 | 1.678087e-06 | 7.101029e-05 | 1.555470e-05 | 7.530197e-07 | 5.822362e-04 | 1.981863e-06 |\n",
       "| TCGA-BA-5556-01A | 0.75529120 | 0.0435331604 | 2.952937e-07 | 1.207894e-01 | 0.05357313 | 1.173000e-03 | 1.222990e-03 | 1.506610e-02 | 5.626280e-03 | 2.814119e-04 | 3.438276e-03 | 4.800570e-06 |\n",
       "| TCGA-P3-A6SX-01A | 0.83130458 | 0.1287847942 | 1.748934e-02 | 8.543231e-07 | 0.02133848 | 8.273896e-07 | 7.626181e-07 | 6.959556e-06 | 5.326699e-06 | 6.660487e-05 | 1.528918e-06 | 9.999336e-04 |\n",
       "| TCGA-CV-7242-11A | 0.92033599 | 0.0167292415 | 2.856326e-05 | 2.252533e-02 | 0.02640606 | 1.401460e-04 | 6.212577e-06 | 5.814562e-03 | 1.092367e-03 | 2.778300e-04 | 4.396532e-03 | 2.247169e-03 |\n",
       "| TCGA-DQ-7592-01A | 0.77657213 | 0.1480833868 | 2.153864e-02 | 1.267932e-02 | 0.03047937 | 1.026445e-06 | 1.200417e-04 | 5.320939e-03 | 3.126022e-03 | 1.418083e-04 | 8.122057e-04 | 1.125114e-03 |\n",
       "| TCGA-CV-6937-01A | 0.73210512 | 0.1790558892 | 6.920554e-07 | 6.051790e-02 | 0.02371145 | 1.595918e-06 | 6.121839e-06 | 7.725410e-06 | 1.605688e-03 | 8.751306e-05 | 2.877875e-03 | 2.242220e-05 |\n",
       "| TCGA-QK-A8ZB-01A | 0.79596447 | 0.1401419183 | 4.915362e-07 | 8.707466e-03 | 0.03265857 | 1.130815e-02 | 3.749270e-06 | 1.149054e-03 | 5.090307e-04 | 5.001437e-04 | 1.466250e-03 | 7.590702e-03 |\n",
       "| TCGA-CV-7432-01A | 0.94571467 | 0.0278294623 | 5.025951e-07 | 3.079319e-03 | 0.01995220 | 5.053822e-07 | 4.289658e-06 | 1.538838e-04 | 9.925769e-04 | 1.938185e-04 | 3.044177e-04 | 1.774354e-03 |\n",
       "| TCGA-CV-7089-01A | 0.91499981 | 0.0174213920 | 4.626392e-07 | 1.222554e-02 | 0.04590122 | 1.101232e-05 | 6.832658e-06 | 4.987475e-03 | 1.076935e-03 | 7.491191e-04 | 8.436417e-04 | 1.776548e-03 |\n",
       "| TCGA-CV-6939-11A | 0.06391068 | 0.0396254273 | 8.779284e-01 | 2.021104e-07 | 0.01853427 | 1.534907e-07 | 1.507802e-07 | 1.420393e-07 | 1.391324e-07 | 1.071993e-07 | 1.602020e-07 | 1.505424e-07 |\n",
       "| TCGA-BA-4075-01A | 0.87501961 | 0.0459568350 | 4.980788e-03 | 3.187023e-02 | 0.02971568 | 9.156259e-07 | 3.094603e-06 | 1.469122e-03 | 1.378718e-03 | 4.420085e-05 | 2.148848e-05 | 9.539326e-03 |\n",
       "| TCGA-T3-A92M-01A | 0.54021403 | 0.3363094290 | 4.086668e-07 | 7.850835e-02 | 0.02452715 | 5.053911e-03 | 4.321249e-06 | 4.535910e-03 | 6.457165e-03 | 2.093600e-04 | 7.437517e-04 | 3.436222e-03 |\n",
       "| ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ |\n",
       "| TCGA-CV-7430-01A | 0.9522944 | 0.021582735 | 7.895697e-07 | 5.593641e-04 | 0.0220002455 | 2.510364e-05 | 3.829535e-06 | 9.251480e-04 | 6.417269e-06 | 1.467724e-04 | 2.901787e-05 | 2.426159e-03 |\n",
       "| TCGA-D6-A74Q-01A | 0.8145015 | 0.112548057 | 8.259003e-07 | 3.924812e-03 | 0.0272028640 | 7.791500e-03 | 3.423638e-05 | 3.396870e-03 | 8.751835e-03 | 3.830402e-03 | 5.718750e-03 | 1.229835e-02 |\n",
       "| TCGA-CV-7255-01A | 0.9085115 | 0.029518875 | 1.604425e-02 | 7.154988e-07 | 0.0437404879 | 1.095024e-06 | 6.808349e-07 | 1.552601e-04 | 5.681043e-04 | 2.181712e-05 | 4.695111e-07 | 1.436786e-03 |\n",
       "| TCGA-CQ-6223-01A | 0.9457482 | 0.018397980 | 3.876277e-07 | 1.391535e-02 | 0.0106591300 | 8.026109e-04 | 3.619042e-05 | 4.574028e-03 | 8.657860e-04 | 8.635799e-04 | 1.685840e-03 | 2.450946e-03 |\n",
       "| TCGA-CV-A460-01A | 0.6303024 | 0.164898903 | 6.629139e-07 | 6.736238e-02 | 0.0735747653 | 6.520934e-03 | 2.105745e-02 | 1.550624e-02 | 6.425260e-03 | 6.974457e-04 | 6.324749e-03 | 7.328822e-03 |\n",
       "| TCGA-CV-7261-01A | 0.6848085 | 0.222022093 | 1.024530e-06 | 2.907047e-02 | 0.0515304559 | 4.028455e-03 | 7.093352e-06 | 1.264518e-03 | 7.358057e-06 | 4.046752e-04 | 2.081536e-04 | 6.647187e-03 |\n",
       "| TCGA-CN-4736-01A | 0.4435007 | 0.203851719 | 1.835070e-01 | 1.121733e-01 | 0.0493733818 | 3.042112e-07 | 5.745673e-04 | 4.504487e-03 | 2.201801e-03 | 2.797655e-07 | 3.094837e-04 | 2.977295e-06 |\n",
       "| TCGA-CR-7404-01A | 0.7707652 | 0.050124414 | 6.147691e-07 | 6.723222e-02 | 0.0644535513 | 8.109896e-03 | 1.245529e-03 | 1.678593e-02 | 4.956443e-03 | 7.647812e-04 | 9.602612e-03 | 5.958792e-03 |\n",
       "| TCGA-UF-A719-01A | 0.9247836 | 0.024351152 | 9.032943e-05 | 3.394154e-03 | 0.0356415653 | 4.339135e-04 | 6.728553e-05 | 4.072791e-03 | 2.117762e-03 | 3.964999e-05 | 9.811350e-04 | 4.026614e-03 |\n",
       "| TCGA-CV-7236-01A | 0.6923188 | 0.196991255 | 5.414749e-07 | 2.256574e-02 | 0.0749498741 | 2.022737e-04 | 1.901099e-06 | 1.387850e-05 | 1.457108e-03 | 1.077066e-04 | 5.148918e-04 | 1.087603e-02 |\n",
       "| TCGA-CV-6951-01A | 0.8573459 | 0.080220851 | 4.729976e-02 | 1.689773e-03 | 0.0125731713 | 6.263061e-07 | 1.552862e-06 | 5.196739e-06 | 3.337689e-06 | 6.550422e-04 | 7.414515e-05 | 1.306809e-04 |\n",
       "| TCGA-CN-4728-01A | 0.2144844 | 0.580468135 | 8.110333e-03 | 1.493368e-01 | 0.0409370445 | 6.582277e-04 | 3.371294e-06 | 4.450652e-03 | 8.723386e-06 | 4.704836e-04 | 1.053649e-03 | 1.817814e-05 |\n",
       "| TCGA-CV-7090-01A | 0.6009539 | 0.249057663 | 2.993599e-07 | 6.615897e-02 | 0.0689356737 | 1.220777e-06 | 1.710834e-06 | 9.923544e-03 | 9.706727e-05 | 2.877527e-04 | 7.086549e-05 | 4.511355e-03 |\n",
       "| TCGA-CV-5979-01A | 0.8908949 | 0.055552577 | 1.539655e-03 | 8.153458e-03 | 0.0366240069 | 5.814996e-07 | 2.301133e-06 | 7.191630e-03 | 6.528483e-06 | 2.030841e-05 | 1.451474e-06 | 1.265226e-05 |\n",
       "| TCGA-CQ-7069-01A | 0.8278284 | 0.092959285 | 4.770939e-07 | 4.438142e-04 | 0.0685432957 | 1.175565e-06 | 2.642127e-06 | 8.358562e-03 | 3.649764e-06 | 2.885009e-04 | 1.919992e-05 | 1.551036e-03 |\n",
       "| TCGA-CN-4733-01A | 0.3456848 | 0.285705707 | 1.686708e-02 | 1.685431e-01 | 0.0972987967 | 1.683155e-02 | 3.003044e-05 | 3.209453e-02 | 8.573240e-03 | 1.672578e-03 | 2.323855e-02 | 3.460009e-03 |\n",
       "| TCGA-CR-7390-01A | 0.7451947 | 0.213920663 | 4.301343e-07 | 5.872467e-03 | 0.0303656461 | 2.065906e-05 | 1.787416e-06 | 7.774182e-06 | 2.897329e-06 | 1.662505e-04 | 1.206895e-06 | 4.445526e-03 |\n",
       "| TCGA-CV-A45X-01A | 0.9493245 | 0.020004646 | 1.110329e-06 | 5.965875e-03 | 0.0168099053 | 4.567125e-05 | 6.166679e-06 | 1.847638e-03 | 2.337816e-03 | 6.785496e-05 | 7.777258e-04 | 2.811138e-03 |\n",
       "| TCGA-IQ-A6SH-01A | 0.8961116 | 0.036440188 | 6.732549e-07 | 2.994372e-02 | 0.0275554746 | 9.626654e-04 | 2.418314e-05 | 7.269247e-03 | 4.617974e-04 | 3.226413e-04 | 6.891492e-04 | 2.186796e-04 |\n",
       "| TCGA-CV-6962-11A | 0.9204774 | 0.037895283 | 1.048223e-04 | 4.559363e-03 | 0.0287513385 | 7.001844e-04 | 2.465428e-06 | 2.058588e-03 | 8.891491e-04 | 4.198810e-04 | 2.243572e-03 | 1.897996e-03 |\n",
       "| TCGA-CV-6960-11A | 0.9469077 | 0.011001313 | 9.216748e-05 | 1.009368e-02 | 0.0269575408 | 2.643422e-05 | 3.702759e-06 | 1.202062e-03 | 1.391011e-05 | 8.802926e-04 | 1.712646e-03 | 1.108602e-03 |\n",
       "| TCGA-CV-A464-01A | 0.4956189 | 0.365218102 | 7.221133e-02 | 1.037947e-02 | 0.0492785176 | 4.868739e-07 | 3.738478e-06 | 4.140700e-03 | 5.425213e-04 | 8.347710e-05 | 2.516128e-03 | 6.623413e-06 |\n",
       "| TCGA-C9-A47Z-01A | 0.9618175 | 0.012865199 | 6.463346e-03 | 2.924776e-03 | 0.0127283062 | 1.794621e-05 | 2.189491e-05 | 1.659820e-03 | 1.646568e-04 | 2.586389e-05 | 1.264258e-04 | 1.184250e-03 |\n",
       "| TCGA-CN-6010-01A | 0.7090638 | 0.092435372 | 1.907857e-02 | 1.028982e-01 | 0.0686872297 | 6.985689e-03 | 1.609571e-06 | 2.066856e-05 | 4.058772e-06 | 8.159275e-04 | 1.319148e-06 | 7.523645e-06 |\n",
       "| TCGA-WA-A7GZ-11A | 0.2250252 | 0.011840187 | 7.626023e-01 | 2.209323e-07 | 0.0005308816 | 1.593409e-07 | 1.963554e-07 | 1.654410e-07 | 1.732265e-07 | 1.398135e-07 | 2.031713e-07 | 1.826388e-07 |\n",
       "| TCGA-CV-7235-01A | 0.5571721 | 0.331035588 | 2.944636e-07 | 4.341405e-02 | 0.0517575839 | 3.909553e-07 | 6.524707e-04 | 1.192152e-02 | 1.210964e-03 | 3.739575e-04 | 7.400603e-04 | 1.721061e-03 |\n",
       "| TCGA-CX-7086-01A | 0.9359061 | 0.013663174 | 1.266288e-06 | 5.613298e-03 | 0.0325342298 | 1.092963e-03 | 5.436330e-04 | 5.968087e-03 | 1.168945e-05 | 6.030335e-05 | 2.253336e-03 | 2.351940e-03 |\n",
       "| TCGA-CV-6935-11A | 0.9228189 | 0.009082117 | 6.677475e-04 | 3.730673e-02 | 0.0272978745 | 3.001992e-04 | 1.349548e-06 | 1.229702e-03 | 2.754238e-04 | 4.052511e-04 | 2.227567e-05 | 5.923958e-04 |\n",
       "| TCGA-P3-A6SW-01A | 0.7411353 | 0.087745865 | 7.265310e-07 | 4.834572e-02 | 0.0502441143 | 2.081898e-02 | 1.012480e-03 | 1.718169e-02 | 1.708835e-02 | 2.908469e-03 | 1.350914e-02 | 9.189827e-06 |\n",
       "| TCGA-HD-A6HZ-01A | 0.6657255 | 0.117164007 | 6.468833e-02 | 5.056453e-02 | 0.0618777771 | 8.469815e-03 | 1.001852e-02 | 4.467721e-03 | 7.463512e-03 | 3.987480e-04 | 2.939265e-03 | 6.222276e-03 |\n",
       "\n"
      ],
      "text/plain": [
       "                 tumor      Fibroblast   tconv.cells  Macrophage   Endothelial \n",
       "TCGA-BB-4224-01A 0.92733662 0.0190890154 6.065475e-03 1.667066e-02 0.01899481  \n",
       "TCGA-H7-7774-01A 0.96023355 0.0005243755 5.746715e-07 1.726243e-02 0.01281692  \n",
       "TCGA-CV-6943-01A 0.42282326 0.3809782307 2.688987e-07 1.322473e-01 0.03871532  \n",
       "TCGA-CN-5374-01A 0.83038369 0.0225637668 1.306061e-02 4.280413e-02 0.03776265  \n",
       "TCGA-CQ-6227-01A 0.54102366 0.2412421894 1.263138e-01 2.588085e-03 0.08882163  \n",
       "TCGA-CV-6959-01A 0.69115943 0.0868143815 1.119808e-01 2.803121e-02 0.07513598  \n",
       "TCGA-F7-A61V-01A 0.89525067 0.0239154964 5.635728e-02 3.346720e-06 0.01864397  \n",
       "TCGA-CV-7413-01A 0.70027072 0.2378109744 2.712702e-07 4.017224e-02 0.01394333  \n",
       "TCGA-CV-7247-01A 0.66569777 0.1485187444 1.370786e-01 7.200252e-07 0.04870135  \n",
       "TCGA-CR-5249-01A 0.76454367 0.0443576958 4.213912e-07 6.687471e-02 0.05448906  \n",
       "TCGA-CQ-5331-01A 0.78235360 0.0407393114 2.118289e-07 1.037272e-01 0.05794117  \n",
       "TCGA-BB-8601-01A 0.97476402 0.0077573390 1.299555e-06 2.344031e-06 0.01377502  \n",
       "TCGA-CV-A45W-01A 0.64501228 0.1003736426 7.634465e-07 8.972898e-02 0.08118746  \n",
       "TCGA-CQ-7063-01A 0.82795833 0.0157717693 6.395263e-07 1.071989e-01 0.03522953  \n",
       "TCGA-CN-5373-01A 0.68797000 0.2299667361 4.758960e-04 4.220190e-02 0.02621258  \n",
       "TCGA-CV-A45T-01A 0.71773096 0.0708530723 3.141035e-02 9.147216e-02 0.04497311  \n",
       "TCGA-HD-A4C1-01A 0.84885450 0.1035910946 4.463907e-07 5.817188e-03 0.03405969  \n",
       "TCGA-CV-7438-11A 0.92346829 0.0107794372 8.169412e-03 2.102821e-02 0.01697486  \n",
       "TCGA-CV-5444-01A 0.27918413 0.5265173593 4.695905e-02 1.093472e-01 0.03731843  \n",
       "TCGA-BA-5556-01A 0.75529120 0.0435331604 2.952937e-07 1.207894e-01 0.05357313  \n",
       "TCGA-P3-A6SX-01A 0.83130458 0.1287847942 1.748934e-02 8.543231e-07 0.02133848  \n",
       "TCGA-CV-7242-11A 0.92033599 0.0167292415 2.856326e-05 2.252533e-02 0.02640606  \n",
       "TCGA-DQ-7592-01A 0.77657213 0.1480833868 2.153864e-02 1.267932e-02 0.03047937  \n",
       "TCGA-CV-6937-01A 0.73210512 0.1790558892 6.920554e-07 6.051790e-02 0.02371145  \n",
       "TCGA-QK-A8ZB-01A 0.79596447 0.1401419183 4.915362e-07 8.707466e-03 0.03265857  \n",
       "TCGA-CV-7432-01A 0.94571467 0.0278294623 5.025951e-07 3.079319e-03 0.01995220  \n",
       "TCGA-CV-7089-01A 0.91499981 0.0174213920 4.626392e-07 1.222554e-02 0.04590122  \n",
       "TCGA-CV-6939-11A 0.06391068 0.0396254273 8.779284e-01 2.021104e-07 0.01853427  \n",
       "TCGA-BA-4075-01A 0.87501961 0.0459568350 4.980788e-03 3.187023e-02 0.02971568  \n",
       "TCGA-T3-A92M-01A 0.54021403 0.3363094290 4.086668e-07 7.850835e-02 0.02452715  \n",
       "⋮                ⋮          ⋮            ⋮            ⋮            ⋮           \n",
       "TCGA-CV-7430-01A 0.9522944  0.021582735  7.895697e-07 5.593641e-04 0.0220002455\n",
       "TCGA-D6-A74Q-01A 0.8145015  0.112548057  8.259003e-07 3.924812e-03 0.0272028640\n",
       "TCGA-CV-7255-01A 0.9085115  0.029518875  1.604425e-02 7.154988e-07 0.0437404879\n",
       "TCGA-CQ-6223-01A 0.9457482  0.018397980  3.876277e-07 1.391535e-02 0.0106591300\n",
       "TCGA-CV-A460-01A 0.6303024  0.164898903  6.629139e-07 6.736238e-02 0.0735747653\n",
       "TCGA-CV-7261-01A 0.6848085  0.222022093  1.024530e-06 2.907047e-02 0.0515304559\n",
       "TCGA-CN-4736-01A 0.4435007  0.203851719  1.835070e-01 1.121733e-01 0.0493733818\n",
       "TCGA-CR-7404-01A 0.7707652  0.050124414  6.147691e-07 6.723222e-02 0.0644535513\n",
       "TCGA-UF-A719-01A 0.9247836  0.024351152  9.032943e-05 3.394154e-03 0.0356415653\n",
       "TCGA-CV-7236-01A 0.6923188  0.196991255  5.414749e-07 2.256574e-02 0.0749498741\n",
       "TCGA-CV-6951-01A 0.8573459  0.080220851  4.729976e-02 1.689773e-03 0.0125731713\n",
       "TCGA-CN-4728-01A 0.2144844  0.580468135  8.110333e-03 1.493368e-01 0.0409370445\n",
       "TCGA-CV-7090-01A 0.6009539  0.249057663  2.993599e-07 6.615897e-02 0.0689356737\n",
       "TCGA-CV-5979-01A 0.8908949  0.055552577  1.539655e-03 8.153458e-03 0.0366240069\n",
       "TCGA-CQ-7069-01A 0.8278284  0.092959285  4.770939e-07 4.438142e-04 0.0685432957\n",
       "TCGA-CN-4733-01A 0.3456848  0.285705707  1.686708e-02 1.685431e-01 0.0972987967\n",
       "TCGA-CR-7390-01A 0.7451947  0.213920663  4.301343e-07 5.872467e-03 0.0303656461\n",
       "TCGA-CV-A45X-01A 0.9493245  0.020004646  1.110329e-06 5.965875e-03 0.0168099053\n",
       "TCGA-IQ-A6SH-01A 0.8961116  0.036440188  6.732549e-07 2.994372e-02 0.0275554746\n",
       "TCGA-CV-6962-11A 0.9204774  0.037895283  1.048223e-04 4.559363e-03 0.0287513385\n",
       "TCGA-CV-6960-11A 0.9469077  0.011001313  9.216748e-05 1.009368e-02 0.0269575408\n",
       "TCGA-CV-A464-01A 0.4956189  0.365218102  7.221133e-02 1.037947e-02 0.0492785176\n",
       "TCGA-C9-A47Z-01A 0.9618175  0.012865199  6.463346e-03 2.924776e-03 0.0127283062\n",
       "TCGA-CN-6010-01A 0.7090638  0.092435372  1.907857e-02 1.028982e-01 0.0686872297\n",
       "TCGA-WA-A7GZ-11A 0.2250252  0.011840187  7.626023e-01 2.209323e-07 0.0005308816\n",
       "TCGA-CV-7235-01A 0.5571721  0.331035588  2.944636e-07 4.341405e-02 0.0517575839\n",
       "TCGA-CX-7086-01A 0.9359061  0.013663174  1.266288e-06 5.613298e-03 0.0325342298\n",
       "TCGA-CV-6935-11A 0.9228189  0.009082117  6.677475e-04 3.730673e-02 0.0272978745\n",
       "TCGA-P3-A6SW-01A 0.7411353  0.087745865  7.265310e-07 4.834572e-02 0.0502441143\n",
       "TCGA-HD-A6HZ-01A 0.6657255  0.117164007  6.468833e-02 5.056453e-02 0.0618777771\n",
       "                 b.cells      cd14.cells   cd8.cells    treg.cells  \n",
       "TCGA-BB-4224-01A 7.521237e-07 2.923092e-05 5.354050e-03 3.046525e-04\n",
       "TCGA-H7-7774-01A 2.474022e-04 1.642298e-05 6.565494e-03 7.144899e-04\n",
       "TCGA-CV-6943-01A 3.798463e-03 4.150265e-06 1.605742e-02 1.883073e-03\n",
       "TCGA-CN-5374-01A 5.620612e-03 2.203963e-03 1.479093e-02 2.010434e-02\n",
       "TCGA-CQ-6227-01A 2.847449e-07 1.274629e-06 1.352857e-06 8.880127e-07\n",
       "TCGA-CV-6959-01A 5.509745e-04 5.064183e-06 2.347650e-03 5.516346e-06\n",
       "TCGA-F7-A61V-01A 3.553009e-04 2.959224e-06 5.670216e-04 2.310520e-03\n",
       "TCGA-CV-7413-01A 3.587617e-05 1.339581e-06 6.724798e-03 8.944177e-04\n",
       "TCGA-CV-7247-01A 2.212088e-07 4.943082e-07 5.189074e-07 4.846298e-07\n",
       "TCGA-CR-5249-01A 8.501797e-03 4.055520e-03 1.371104e-02 1.656411e-02\n",
       "TCGA-CQ-5331-01A 5.733758e-04 3.486812e-06 9.742968e-03 1.747090e-03\n",
       "TCGA-BB-8601-01A 1.731479e-03 2.661071e-06 1.341848e-05 8.569433e-06\n",
       "TCGA-CV-A45W-01A 5.304755e-02 4.668449e-06 9.988465e-03 8.800786e-03\n",
       "TCGA-CQ-7063-01A 1.307273e-06 5.571277e-06 9.594590e-03 9.372649e-04\n",
       "TCGA-CN-5373-01A 6.849174e-05 1.352270e-05 1.085064e-02 4.261388e-06\n",
       "TCGA-CV-A45T-01A 4.805633e-03 8.073109e-06 2.740484e-02 8.359557e-03\n",
       "TCGA-HD-A4C1-01A 8.387271e-04 3.536181e-06 2.643809e-03 2.087295e-05\n",
       "TCGA-CV-7438-11A 1.778206e-03 9.754485e-05 9.765350e-03 1.629515e-03\n",
       "TCGA-CV-5444-01A 6.596345e-07 1.678087e-06 7.101029e-05 1.555470e-05\n",
       "TCGA-BA-5556-01A 1.173000e-03 1.222990e-03 1.506610e-02 5.626280e-03\n",
       "TCGA-P3-A6SX-01A 8.273896e-07 7.626181e-07 6.959556e-06 5.326699e-06\n",
       "TCGA-CV-7242-11A 1.401460e-04 6.212577e-06 5.814562e-03 1.092367e-03\n",
       "TCGA-DQ-7592-01A 1.026445e-06 1.200417e-04 5.320939e-03 3.126022e-03\n",
       "TCGA-CV-6937-01A 1.595918e-06 6.121839e-06 7.725410e-06 1.605688e-03\n",
       "TCGA-QK-A8ZB-01A 1.130815e-02 3.749270e-06 1.149054e-03 5.090307e-04\n",
       "TCGA-CV-7432-01A 5.053822e-07 4.289658e-06 1.538838e-04 9.925769e-04\n",
       "TCGA-CV-7089-01A 1.101232e-05 6.832658e-06 4.987475e-03 1.076935e-03\n",
       "TCGA-CV-6939-11A 1.534907e-07 1.507802e-07 1.420393e-07 1.391324e-07\n",
       "TCGA-BA-4075-01A 9.156259e-07 3.094603e-06 1.469122e-03 1.378718e-03\n",
       "TCGA-T3-A92M-01A 5.053911e-03 4.321249e-06 4.535910e-03 6.457165e-03\n",
       "⋮                ⋮            ⋮            ⋮            ⋮           \n",
       "TCGA-CV-7430-01A 2.510364e-05 3.829535e-06 9.251480e-04 6.417269e-06\n",
       "TCGA-D6-A74Q-01A 7.791500e-03 3.423638e-05 3.396870e-03 8.751835e-03\n",
       "TCGA-CV-7255-01A 1.095024e-06 6.808349e-07 1.552601e-04 5.681043e-04\n",
       "TCGA-CQ-6223-01A 8.026109e-04 3.619042e-05 4.574028e-03 8.657860e-04\n",
       "TCGA-CV-A460-01A 6.520934e-03 2.105745e-02 1.550624e-02 6.425260e-03\n",
       "TCGA-CV-7261-01A 4.028455e-03 7.093352e-06 1.264518e-03 7.358057e-06\n",
       "TCGA-CN-4736-01A 3.042112e-07 5.745673e-04 4.504487e-03 2.201801e-03\n",
       "TCGA-CR-7404-01A 8.109896e-03 1.245529e-03 1.678593e-02 4.956443e-03\n",
       "TCGA-UF-A719-01A 4.339135e-04 6.728553e-05 4.072791e-03 2.117762e-03\n",
       "TCGA-CV-7236-01A 2.022737e-04 1.901099e-06 1.387850e-05 1.457108e-03\n",
       "TCGA-CV-6951-01A 6.263061e-07 1.552862e-06 5.196739e-06 3.337689e-06\n",
       "TCGA-CN-4728-01A 6.582277e-04 3.371294e-06 4.450652e-03 8.723386e-06\n",
       "TCGA-CV-7090-01A 1.220777e-06 1.710834e-06 9.923544e-03 9.706727e-05\n",
       "TCGA-CV-5979-01A 5.814996e-07 2.301133e-06 7.191630e-03 6.528483e-06\n",
       "TCGA-CQ-7069-01A 1.175565e-06 2.642127e-06 8.358562e-03 3.649764e-06\n",
       "TCGA-CN-4733-01A 1.683155e-02 3.003044e-05 3.209453e-02 8.573240e-03\n",
       "TCGA-CR-7390-01A 2.065906e-05 1.787416e-06 7.774182e-06 2.897329e-06\n",
       "TCGA-CV-A45X-01A 4.567125e-05 6.166679e-06 1.847638e-03 2.337816e-03\n",
       "TCGA-IQ-A6SH-01A 9.626654e-04 2.418314e-05 7.269247e-03 4.617974e-04\n",
       "TCGA-CV-6962-11A 7.001844e-04 2.465428e-06 2.058588e-03 8.891491e-04\n",
       "TCGA-CV-6960-11A 2.643422e-05 3.702759e-06 1.202062e-03 1.391011e-05\n",
       "TCGA-CV-A464-01A 4.868739e-07 3.738478e-06 4.140700e-03 5.425213e-04\n",
       "TCGA-C9-A47Z-01A 1.794621e-05 2.189491e-05 1.659820e-03 1.646568e-04\n",
       "TCGA-CN-6010-01A 6.985689e-03 1.609571e-06 2.066856e-05 4.058772e-06\n",
       "TCGA-WA-A7GZ-11A 1.593409e-07 1.963554e-07 1.654410e-07 1.732265e-07\n",
       "TCGA-CV-7235-01A 3.909553e-07 6.524707e-04 1.192152e-02 1.210964e-03\n",
       "TCGA-CX-7086-01A 1.092963e-03 5.436330e-04 5.968087e-03 1.168945e-05\n",
       "TCGA-CV-6935-11A 3.001992e-04 1.349548e-06 1.229702e-03 2.754238e-04\n",
       "TCGA-P3-A6SW-01A 2.081898e-02 1.012480e-03 1.718169e-02 1.708835e-02\n",
       "TCGA-HD-A6HZ-01A 8.469815e-03 1.001852e-02 4.467721e-03 7.463512e-03\n",
       "                 mast.cells   pdc.cells    nk.cells    \n",
       "TCGA-BB-4224-01A 1.783831e-04 1.032630e-03 4.943720e-03\n",
       "TCGA-H7-7774-01A 5.097020e-04 1.077549e-03 3.108857e-05\n",
       "TCGA-CV-6943-01A 7.728221e-04 2.718970e-03 7.299435e-07\n",
       "TCGA-CN-5374-01A 5.407611e-04 6.411098e-03 3.753455e-03\n",
       "TCGA-CQ-6227-01A 5.012126e-07 1.886387e-06 4.404987e-06\n",
       "TCGA-CV-6959-01A 3.417677e-07 1.351226e-05 3.955105e-03\n",
       "TCGA-F7-A61V-01A 4.332584e-07 1.550082e-03 1.042917e-03\n",
       "TCGA-CV-7413-01A 1.404934e-04 3.144350e-06 2.394474e-06\n",
       "TCGA-CV-7247-01A 1.806964e-07 3.395621e-07 5.455221e-07\n",
       "TCGA-CR-5249-01A 1.112755e-03 1.360507e-02 1.218416e-02\n",
       "TCGA-CQ-5331-01A 7.207214e-05 3.096985e-03 2.579330e-06\n",
       "TCGA-BB-8601-01A 7.369978e-04 3.643543e-06 1.203214e-03\n",
       "TCGA-CV-A45W-01A 7.019862e-04 6.153426e-03 4.999988e-03\n",
       "TCGA-CQ-7063-01A 6.160940e-04 2.668512e-03 1.747479e-05\n",
       "TCGA-CN-5373-01A 4.745499e-04 1.702080e-03 5.933012e-05\n",
       "TCGA-CV-A45T-01A 3.344305e-04 2.609326e-03 3.848610e-05\n",
       "TCGA-HD-A4C1-01A 5.490139e-07 7.022697e-04 3.467318e-03\n",
       "TCGA-CV-7438-11A 3.635568e-04 4.535285e-03 1.410328e-03\n",
       "TCGA-CV-5444-01A 7.530197e-07 5.822362e-04 1.981863e-06\n",
       "TCGA-BA-5556-01A 2.814119e-04 3.438276e-03 4.800570e-06\n",
       "TCGA-P3-A6SX-01A 6.660487e-05 1.528918e-06 9.999336e-04\n",
       "TCGA-CV-7242-11A 2.778300e-04 4.396532e-03 2.247169e-03\n",
       "TCGA-DQ-7592-01A 1.418083e-04 8.122057e-04 1.125114e-03\n",
       "TCGA-CV-6937-01A 8.751306e-05 2.877875e-03 2.242220e-05\n",
       "TCGA-QK-A8ZB-01A 5.001437e-04 1.466250e-03 7.590702e-03\n",
       "TCGA-CV-7432-01A 1.938185e-04 3.044177e-04 1.774354e-03\n",
       "TCGA-CV-7089-01A 7.491191e-04 8.436417e-04 1.776548e-03\n",
       "TCGA-CV-6939-11A 1.071993e-07 1.602020e-07 1.505424e-07\n",
       "TCGA-BA-4075-01A 4.420085e-05 2.148848e-05 9.539326e-03\n",
       "TCGA-T3-A92M-01A 2.093600e-04 7.437517e-04 3.436222e-03\n",
       "⋮                ⋮            ⋮            ⋮           \n",
       "TCGA-CV-7430-01A 1.467724e-04 2.901787e-05 2.426159e-03\n",
       "TCGA-D6-A74Q-01A 3.830402e-03 5.718750e-03 1.229835e-02\n",
       "TCGA-CV-7255-01A 2.181712e-05 4.695111e-07 1.436786e-03\n",
       "TCGA-CQ-6223-01A 8.635799e-04 1.685840e-03 2.450946e-03\n",
       "TCGA-CV-A460-01A 6.974457e-04 6.324749e-03 7.328822e-03\n",
       "TCGA-CV-7261-01A 4.046752e-04 2.081536e-04 6.647187e-03\n",
       "TCGA-CN-4736-01A 2.797655e-07 3.094837e-04 2.977295e-06\n",
       "TCGA-CR-7404-01A 7.647812e-04 9.602612e-03 5.958792e-03\n",
       "TCGA-UF-A719-01A 3.964999e-05 9.811350e-04 4.026614e-03\n",
       "TCGA-CV-7236-01A 1.077066e-04 5.148918e-04 1.087603e-02\n",
       "TCGA-CV-6951-01A 6.550422e-04 7.414515e-05 1.306809e-04\n",
       "TCGA-CN-4728-01A 4.704836e-04 1.053649e-03 1.817814e-05\n",
       "TCGA-CV-7090-01A 2.877527e-04 7.086549e-05 4.511355e-03\n",
       "TCGA-CV-5979-01A 2.030841e-05 1.451474e-06 1.265226e-05\n",
       "TCGA-CQ-7069-01A 2.885009e-04 1.919992e-05 1.551036e-03\n",
       "TCGA-CN-4733-01A 1.672578e-03 2.323855e-02 3.460009e-03\n",
       "TCGA-CR-7390-01A 1.662505e-04 1.206895e-06 4.445526e-03\n",
       "TCGA-CV-A45X-01A 6.785496e-05 7.777258e-04 2.811138e-03\n",
       "TCGA-IQ-A6SH-01A 3.226413e-04 6.891492e-04 2.186796e-04\n",
       "TCGA-CV-6962-11A 4.198810e-04 2.243572e-03 1.897996e-03\n",
       "TCGA-CV-6960-11A 8.802926e-04 1.712646e-03 1.108602e-03\n",
       "TCGA-CV-A464-01A 8.347710e-05 2.516128e-03 6.623413e-06\n",
       "TCGA-C9-A47Z-01A 2.586389e-05 1.264258e-04 1.184250e-03\n",
       "TCGA-CN-6010-01A 8.159275e-04 1.319148e-06 7.523645e-06\n",
       "TCGA-WA-A7GZ-11A 1.398135e-07 2.031713e-07 1.826388e-07\n",
       "TCGA-CV-7235-01A 3.739575e-04 7.400603e-04 1.721061e-03\n",
       "TCGA-CX-7086-01A 6.030335e-05 2.253336e-03 2.351940e-03\n",
       "TCGA-CV-6935-11A 4.052511e-04 2.227567e-05 5.923958e-04\n",
       "TCGA-P3-A6SW-01A 2.908469e-03 1.350914e-02 9.189827e-06\n",
       "TCGA-HD-A6HZ-01A 3.987480e-04 2.939265e-03 6.222276e-03"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "#final est cell type fraction in each bulk samples\n",
    "res$res$final.gibbs.thet"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 44,
   "id": "53d342b8",
   "metadata": {},
   "outputs": [],
   "source": [
    "get_BP_res <- function(res){\n",
    "    BP_res <- data.frame(res$res$final.gibbs.thet)\n",
    "    colnames(BP_res)[3] <- 'Tconv-cell'\n",
    "    colnames(BP_res)[6] <- 'B-cells'\n",
    "    colnames(BP_res)[7] <- 'CD14-cells'\n",
    "    colnames(BP_res)[8] <- 'CD8-cells'\n",
    "    colnames(BP_res)[9] <- 'Treg-cells'\n",
    "    colnames(BP_res)[10] <- 'Mast'\n",
    "    colnames(BP_res)[11] <- 'pDC-cells'\n",
    "    colnames(BP_res)[12] <- 'NK-cells'\n",
    "    BP_res <- BP_res[, order(names(BP_res))]\n",
    "    return(BP_res)\n",
    "}"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 45,
   "id": "a2a809c4",
   "metadata": {},
   "outputs": [],
   "source": [
    "BP_res <- get_BP_res(res)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 46,
   "id": "c722f761",
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<table class=\"dataframe\">\n",
       "<caption>A data.frame: 546 × 12</caption>\n",
       "<thead>\n",
       "\t<tr><th></th><th scope=col>B-cells</th><th scope=col>CD14-cells</th><th scope=col>CD8-cells</th><th scope=col>Endothelial</th><th scope=col>Fibroblast</th><th scope=col>Macrophage</th><th scope=col>Mast</th><th scope=col>NK-cells</th><th scope=col>pDC-cells</th><th scope=col>Tconv-cell</th><th scope=col>Treg-cells</th><th scope=col>tumor</th></tr>\n",
       "\t<tr><th></th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th><th scope=col>&lt;dbl&gt;</th></tr>\n",
       "</thead>\n",
       "<tbody>\n",
       "\t<tr><th scope=row>TCGA-BB-4224-01A</th><td>7.521237e-07</td><td>2.923092e-05</td><td>5.354050e-03</td><td>0.01899481</td><td>0.0190890154</td><td>1.667066e-02</td><td>1.783831e-04</td><td>4.943720e-03</td><td>1.032630e-03</td><td>6.065475e-03</td><td>3.046525e-04</td><td>0.92733662</td></tr>\n",
       "\t<tr><th scope=row>TCGA-H7-7774-01A</th><td>2.474022e-04</td><td>1.642298e-05</td><td>6.565494e-03</td><td>0.01281692</td><td>0.0005243755</td><td>1.726243e-02</td><td>5.097020e-04</td><td>3.108857e-05</td><td>1.077549e-03</td><td>5.746715e-07</td><td>7.144899e-04</td><td>0.96023355</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6943-01A</th><td>3.798463e-03</td><td>4.150265e-06</td><td>1.605742e-02</td><td>0.03871532</td><td>0.3809782307</td><td>1.322473e-01</td><td>7.728221e-04</td><td>7.299435e-07</td><td>2.718970e-03</td><td>2.688987e-07</td><td>1.883073e-03</td><td>0.42282326</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-5374-01A</th><td>5.620612e-03</td><td>2.203963e-03</td><td>1.479093e-02</td><td>0.03776265</td><td>0.0225637668</td><td>4.280413e-02</td><td>5.407611e-04</td><td>3.753455e-03</td><td>6.411098e-03</td><td>1.306061e-02</td><td>2.010434e-02</td><td>0.83038369</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CQ-6227-01A</th><td>2.847449e-07</td><td>1.274629e-06</td><td>1.352857e-06</td><td>0.08882163</td><td>0.2412421894</td><td>2.588085e-03</td><td>5.012126e-07</td><td>4.404987e-06</td><td>1.886387e-06</td><td>1.263138e-01</td><td>8.880127e-07</td><td>0.54102366</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6959-01A</th><td>5.509745e-04</td><td>5.064183e-06</td><td>2.347650e-03</td><td>0.07513598</td><td>0.0868143815</td><td>2.803121e-02</td><td>3.417677e-07</td><td>3.955105e-03</td><td>1.351226e-05</td><td>1.119808e-01</td><td>5.516346e-06</td><td>0.69115943</td></tr>\n",
       "\t<tr><th scope=row>TCGA-F7-A61V-01A</th><td>3.553009e-04</td><td>2.959224e-06</td><td>5.670216e-04</td><td>0.01864397</td><td>0.0239154964</td><td>3.346720e-06</td><td>4.332584e-07</td><td>1.042917e-03</td><td>1.550082e-03</td><td>5.635728e-02</td><td>2.310520e-03</td><td>0.89525067</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7413-01A</th><td>3.587617e-05</td><td>1.339581e-06</td><td>6.724798e-03</td><td>0.01394333</td><td>0.2378109744</td><td>4.017224e-02</td><td>1.404934e-04</td><td>2.394474e-06</td><td>3.144350e-06</td><td>2.712702e-07</td><td>8.944177e-04</td><td>0.70027072</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7247-01A</th><td>2.212088e-07</td><td>4.943082e-07</td><td>5.189074e-07</td><td>0.04870135</td><td>0.1485187444</td><td>7.200252e-07</td><td>1.806964e-07</td><td>5.455221e-07</td><td>3.395621e-07</td><td>1.370786e-01</td><td>4.846298e-07</td><td>0.66569777</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CR-5249-01A</th><td>8.501797e-03</td><td>4.055520e-03</td><td>1.371104e-02</td><td>0.05448906</td><td>0.0443576958</td><td>6.687471e-02</td><td>1.112755e-03</td><td>1.218416e-02</td><td>1.360507e-02</td><td>4.213912e-07</td><td>1.656411e-02</td><td>0.76454367</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CQ-5331-01A</th><td>5.733758e-04</td><td>3.486812e-06</td><td>9.742968e-03</td><td>0.05794117</td><td>0.0407393114</td><td>1.037272e-01</td><td>7.207214e-05</td><td>2.579330e-06</td><td>3.096985e-03</td><td>2.118289e-07</td><td>1.747090e-03</td><td>0.78235360</td></tr>\n",
       "\t<tr><th scope=row>TCGA-BB-8601-01A</th><td>1.731479e-03</td><td>2.661071e-06</td><td>1.341848e-05</td><td>0.01377502</td><td>0.0077573390</td><td>2.344031e-06</td><td>7.369978e-04</td><td>1.203214e-03</td><td>3.643543e-06</td><td>1.299555e-06</td><td>8.569433e-06</td><td>0.97476402</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-A45W-01A</th><td>5.304755e-02</td><td>4.668449e-06</td><td>9.988465e-03</td><td>0.08118746</td><td>0.1003736426</td><td>8.972898e-02</td><td>7.019862e-04</td><td>4.999988e-03</td><td>6.153426e-03</td><td>7.634465e-07</td><td>8.800786e-03</td><td>0.64501228</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CQ-7063-01A</th><td>1.307273e-06</td><td>5.571277e-06</td><td>9.594590e-03</td><td>0.03522953</td><td>0.0157717693</td><td>1.071989e-01</td><td>6.160940e-04</td><td>1.747479e-05</td><td>2.668512e-03</td><td>6.395263e-07</td><td>9.372649e-04</td><td>0.82795833</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-5373-01A</th><td>6.849174e-05</td><td>1.352270e-05</td><td>1.085064e-02</td><td>0.02621258</td><td>0.2299667361</td><td>4.220190e-02</td><td>4.745499e-04</td><td>5.933012e-05</td><td>1.702080e-03</td><td>4.758960e-04</td><td>4.261388e-06</td><td>0.68797000</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-A45T-01A</th><td>4.805633e-03</td><td>8.073109e-06</td><td>2.740484e-02</td><td>0.04497311</td><td>0.0708530723</td><td>9.147216e-02</td><td>3.344305e-04</td><td>3.848610e-05</td><td>2.609326e-03</td><td>3.141035e-02</td><td>8.359557e-03</td><td>0.71773096</td></tr>\n",
       "\t<tr><th scope=row>TCGA-HD-A4C1-01A</th><td>8.387271e-04</td><td>3.536181e-06</td><td>2.643809e-03</td><td>0.03405969</td><td>0.1035910946</td><td>5.817188e-03</td><td>5.490139e-07</td><td>3.467318e-03</td><td>7.022697e-04</td><td>4.463907e-07</td><td>2.087295e-05</td><td>0.84885450</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7438-11A</th><td>1.778206e-03</td><td>9.754485e-05</td><td>9.765350e-03</td><td>0.01697486</td><td>0.0107794372</td><td>2.102821e-02</td><td>3.635568e-04</td><td>1.410328e-03</td><td>4.535285e-03</td><td>8.169412e-03</td><td>1.629515e-03</td><td>0.92346829</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-5444-01A</th><td>6.596345e-07</td><td>1.678087e-06</td><td>7.101029e-05</td><td>0.03731843</td><td>0.5265173593</td><td>1.093472e-01</td><td>7.530197e-07</td><td>1.981863e-06</td><td>5.822362e-04</td><td>4.695905e-02</td><td>1.555470e-05</td><td>0.27918413</td></tr>\n",
       "\t<tr><th scope=row>TCGA-BA-5556-01A</th><td>1.173000e-03</td><td>1.222990e-03</td><td>1.506610e-02</td><td>0.05357313</td><td>0.0435331604</td><td>1.207894e-01</td><td>2.814119e-04</td><td>4.800570e-06</td><td>3.438276e-03</td><td>2.952937e-07</td><td>5.626280e-03</td><td>0.75529120</td></tr>\n",
       "\t<tr><th scope=row>TCGA-P3-A6SX-01A</th><td>8.273896e-07</td><td>7.626181e-07</td><td>6.959556e-06</td><td>0.02133848</td><td>0.1287847942</td><td>8.543231e-07</td><td>6.660487e-05</td><td>9.999336e-04</td><td>1.528918e-06</td><td>1.748934e-02</td><td>5.326699e-06</td><td>0.83130458</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7242-11A</th><td>1.401460e-04</td><td>6.212577e-06</td><td>5.814562e-03</td><td>0.02640606</td><td>0.0167292415</td><td>2.252533e-02</td><td>2.778300e-04</td><td>2.247169e-03</td><td>4.396532e-03</td><td>2.856326e-05</td><td>1.092367e-03</td><td>0.92033599</td></tr>\n",
       "\t<tr><th scope=row>TCGA-DQ-7592-01A</th><td>1.026445e-06</td><td>1.200417e-04</td><td>5.320939e-03</td><td>0.03047937</td><td>0.1480833868</td><td>1.267932e-02</td><td>1.418083e-04</td><td>1.125114e-03</td><td>8.122057e-04</td><td>2.153864e-02</td><td>3.126022e-03</td><td>0.77657213</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6937-01A</th><td>1.595918e-06</td><td>6.121839e-06</td><td>7.725410e-06</td><td>0.02371145</td><td>0.1790558892</td><td>6.051790e-02</td><td>8.751306e-05</td><td>2.242220e-05</td><td>2.877875e-03</td><td>6.920554e-07</td><td>1.605688e-03</td><td>0.73210512</td></tr>\n",
       "\t<tr><th scope=row>TCGA-QK-A8ZB-01A</th><td>1.130815e-02</td><td>3.749270e-06</td><td>1.149054e-03</td><td>0.03265857</td><td>0.1401419183</td><td>8.707466e-03</td><td>5.001437e-04</td><td>7.590702e-03</td><td>1.466250e-03</td><td>4.915362e-07</td><td>5.090307e-04</td><td>0.79596447</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7432-01A</th><td>5.053822e-07</td><td>4.289658e-06</td><td>1.538838e-04</td><td>0.01995220</td><td>0.0278294623</td><td>3.079319e-03</td><td>1.938185e-04</td><td>1.774354e-03</td><td>3.044177e-04</td><td>5.025951e-07</td><td>9.925769e-04</td><td>0.94571467</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7089-01A</th><td>1.101232e-05</td><td>6.832658e-06</td><td>4.987475e-03</td><td>0.04590122</td><td>0.0174213920</td><td>1.222554e-02</td><td>7.491191e-04</td><td>1.776548e-03</td><td>8.436417e-04</td><td>4.626392e-07</td><td>1.076935e-03</td><td>0.91499981</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6939-11A</th><td>1.534907e-07</td><td>1.507802e-07</td><td>1.420393e-07</td><td>0.01853427</td><td>0.0396254273</td><td>2.021104e-07</td><td>1.071993e-07</td><td>1.505424e-07</td><td>1.602020e-07</td><td>8.779284e-01</td><td>1.391324e-07</td><td>0.06391068</td></tr>\n",
       "\t<tr><th scope=row>TCGA-BA-4075-01A</th><td>9.156259e-07</td><td>3.094603e-06</td><td>1.469122e-03</td><td>0.02971568</td><td>0.0459568350</td><td>3.187023e-02</td><td>4.420085e-05</td><td>9.539326e-03</td><td>2.148848e-05</td><td>4.980788e-03</td><td>1.378718e-03</td><td>0.87501961</td></tr>\n",
       "\t<tr><th scope=row>TCGA-T3-A92M-01A</th><td>5.053911e-03</td><td>4.321249e-06</td><td>4.535910e-03</td><td>0.02452715</td><td>0.3363094290</td><td>7.850835e-02</td><td>2.093600e-04</td><td>3.436222e-03</td><td>7.437517e-04</td><td>4.086668e-07</td><td>6.457165e-03</td><td>0.54021403</td></tr>\n",
       "\t<tr><th scope=row>⋮</th><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7430-01A</th><td>2.510364e-05</td><td>3.829535e-06</td><td>9.251480e-04</td><td>0.0220002455</td><td>0.021582735</td><td>5.593641e-04</td><td>1.467724e-04</td><td>2.426159e-03</td><td>2.901787e-05</td><td>7.895697e-07</td><td>6.417269e-06</td><td>0.9522944</td></tr>\n",
       "\t<tr><th scope=row>TCGA-D6-A74Q-01A</th><td>7.791500e-03</td><td>3.423638e-05</td><td>3.396870e-03</td><td>0.0272028640</td><td>0.112548057</td><td>3.924812e-03</td><td>3.830402e-03</td><td>1.229835e-02</td><td>5.718750e-03</td><td>8.259003e-07</td><td>8.751835e-03</td><td>0.8145015</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7255-01A</th><td>1.095024e-06</td><td>6.808349e-07</td><td>1.552601e-04</td><td>0.0437404879</td><td>0.029518875</td><td>7.154988e-07</td><td>2.181712e-05</td><td>1.436786e-03</td><td>4.695111e-07</td><td>1.604425e-02</td><td>5.681043e-04</td><td>0.9085115</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CQ-6223-01A</th><td>8.026109e-04</td><td>3.619042e-05</td><td>4.574028e-03</td><td>0.0106591300</td><td>0.018397980</td><td>1.391535e-02</td><td>8.635799e-04</td><td>2.450946e-03</td><td>1.685840e-03</td><td>3.876277e-07</td><td>8.657860e-04</td><td>0.9457482</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-A460-01A</th><td>6.520934e-03</td><td>2.105745e-02</td><td>1.550624e-02</td><td>0.0735747653</td><td>0.164898903</td><td>6.736238e-02</td><td>6.974457e-04</td><td>7.328822e-03</td><td>6.324749e-03</td><td>6.629139e-07</td><td>6.425260e-03</td><td>0.6303024</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7261-01A</th><td>4.028455e-03</td><td>7.093352e-06</td><td>1.264518e-03</td><td>0.0515304559</td><td>0.222022093</td><td>2.907047e-02</td><td>4.046752e-04</td><td>6.647187e-03</td><td>2.081536e-04</td><td>1.024530e-06</td><td>7.358057e-06</td><td>0.6848085</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-4736-01A</th><td>3.042112e-07</td><td>5.745673e-04</td><td>4.504487e-03</td><td>0.0493733818</td><td>0.203851719</td><td>1.121733e-01</td><td>2.797655e-07</td><td>2.977295e-06</td><td>3.094837e-04</td><td>1.835070e-01</td><td>2.201801e-03</td><td>0.4435007</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CR-7404-01A</th><td>8.109896e-03</td><td>1.245529e-03</td><td>1.678593e-02</td><td>0.0644535513</td><td>0.050124414</td><td>6.723222e-02</td><td>7.647812e-04</td><td>5.958792e-03</td><td>9.602612e-03</td><td>6.147691e-07</td><td>4.956443e-03</td><td>0.7707652</td></tr>\n",
       "\t<tr><th scope=row>TCGA-UF-A719-01A</th><td>4.339135e-04</td><td>6.728553e-05</td><td>4.072791e-03</td><td>0.0356415653</td><td>0.024351152</td><td>3.394154e-03</td><td>3.964999e-05</td><td>4.026614e-03</td><td>9.811350e-04</td><td>9.032943e-05</td><td>2.117762e-03</td><td>0.9247836</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7236-01A</th><td>2.022737e-04</td><td>1.901099e-06</td><td>1.387850e-05</td><td>0.0749498741</td><td>0.196991255</td><td>2.256574e-02</td><td>1.077066e-04</td><td>1.087603e-02</td><td>5.148918e-04</td><td>5.414749e-07</td><td>1.457108e-03</td><td>0.6923188</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6951-01A</th><td>6.263061e-07</td><td>1.552862e-06</td><td>5.196739e-06</td><td>0.0125731713</td><td>0.080220851</td><td>1.689773e-03</td><td>6.550422e-04</td><td>1.306809e-04</td><td>7.414515e-05</td><td>4.729976e-02</td><td>3.337689e-06</td><td>0.8573459</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-4728-01A</th><td>6.582277e-04</td><td>3.371294e-06</td><td>4.450652e-03</td><td>0.0409370445</td><td>0.580468135</td><td>1.493368e-01</td><td>4.704836e-04</td><td>1.817814e-05</td><td>1.053649e-03</td><td>8.110333e-03</td><td>8.723386e-06</td><td>0.2144844</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7090-01A</th><td>1.220777e-06</td><td>1.710834e-06</td><td>9.923544e-03</td><td>0.0689356737</td><td>0.249057663</td><td>6.615897e-02</td><td>2.877527e-04</td><td>4.511355e-03</td><td>7.086549e-05</td><td>2.993599e-07</td><td>9.706727e-05</td><td>0.6009539</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-5979-01A</th><td>5.814996e-07</td><td>2.301133e-06</td><td>7.191630e-03</td><td>0.0366240069</td><td>0.055552577</td><td>8.153458e-03</td><td>2.030841e-05</td><td>1.265226e-05</td><td>1.451474e-06</td><td>1.539655e-03</td><td>6.528483e-06</td><td>0.8908949</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CQ-7069-01A</th><td>1.175565e-06</td><td>2.642127e-06</td><td>8.358562e-03</td><td>0.0685432957</td><td>0.092959285</td><td>4.438142e-04</td><td>2.885009e-04</td><td>1.551036e-03</td><td>1.919992e-05</td><td>4.770939e-07</td><td>3.649764e-06</td><td>0.8278284</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-4733-01A</th><td>1.683155e-02</td><td>3.003044e-05</td><td>3.209453e-02</td><td>0.0972987967</td><td>0.285705707</td><td>1.685431e-01</td><td>1.672578e-03</td><td>3.460009e-03</td><td>2.323855e-02</td><td>1.686708e-02</td><td>8.573240e-03</td><td>0.3456848</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CR-7390-01A</th><td>2.065906e-05</td><td>1.787416e-06</td><td>7.774182e-06</td><td>0.0303656461</td><td>0.213920663</td><td>5.872467e-03</td><td>1.662505e-04</td><td>4.445526e-03</td><td>1.206895e-06</td><td>4.301343e-07</td><td>2.897329e-06</td><td>0.7451947</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-A45X-01A</th><td>4.567125e-05</td><td>6.166679e-06</td><td>1.847638e-03</td><td>0.0168099053</td><td>0.020004646</td><td>5.965875e-03</td><td>6.785496e-05</td><td>2.811138e-03</td><td>7.777258e-04</td><td>1.110329e-06</td><td>2.337816e-03</td><td>0.9493245</td></tr>\n",
       "\t<tr><th scope=row>TCGA-IQ-A6SH-01A</th><td>9.626654e-04</td><td>2.418314e-05</td><td>7.269247e-03</td><td>0.0275554746</td><td>0.036440188</td><td>2.994372e-02</td><td>3.226413e-04</td><td>2.186796e-04</td><td>6.891492e-04</td><td>6.732549e-07</td><td>4.617974e-04</td><td>0.8961116</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6962-11A</th><td>7.001844e-04</td><td>2.465428e-06</td><td>2.058588e-03</td><td>0.0287513385</td><td>0.037895283</td><td>4.559363e-03</td><td>4.198810e-04</td><td>1.897996e-03</td><td>2.243572e-03</td><td>1.048223e-04</td><td>8.891491e-04</td><td>0.9204774</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6960-11A</th><td>2.643422e-05</td><td>3.702759e-06</td><td>1.202062e-03</td><td>0.0269575408</td><td>0.011001313</td><td>1.009368e-02</td><td>8.802926e-04</td><td>1.108602e-03</td><td>1.712646e-03</td><td>9.216748e-05</td><td>1.391011e-05</td><td>0.9469077</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-A464-01A</th><td>4.868739e-07</td><td>3.738478e-06</td><td>4.140700e-03</td><td>0.0492785176</td><td>0.365218102</td><td>1.037947e-02</td><td>8.347710e-05</td><td>6.623413e-06</td><td>2.516128e-03</td><td>7.221133e-02</td><td>5.425213e-04</td><td>0.4956189</td></tr>\n",
       "\t<tr><th scope=row>TCGA-C9-A47Z-01A</th><td>1.794621e-05</td><td>2.189491e-05</td><td>1.659820e-03</td><td>0.0127283062</td><td>0.012865199</td><td>2.924776e-03</td><td>2.586389e-05</td><td>1.184250e-03</td><td>1.264258e-04</td><td>6.463346e-03</td><td>1.646568e-04</td><td>0.9618175</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CN-6010-01A</th><td>6.985689e-03</td><td>1.609571e-06</td><td>2.066856e-05</td><td>0.0686872297</td><td>0.092435372</td><td>1.028982e-01</td><td>8.159275e-04</td><td>7.523645e-06</td><td>1.319148e-06</td><td>1.907857e-02</td><td>4.058772e-06</td><td>0.7090638</td></tr>\n",
       "\t<tr><th scope=row>TCGA-WA-A7GZ-11A</th><td>1.593409e-07</td><td>1.963554e-07</td><td>1.654410e-07</td><td>0.0005308816</td><td>0.011840187</td><td>2.209323e-07</td><td>1.398135e-07</td><td>1.826388e-07</td><td>2.031713e-07</td><td>7.626023e-01</td><td>1.732265e-07</td><td>0.2250252</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-7235-01A</th><td>3.909553e-07</td><td>6.524707e-04</td><td>1.192152e-02</td><td>0.0517575839</td><td>0.331035588</td><td>4.341405e-02</td><td>3.739575e-04</td><td>1.721061e-03</td><td>7.400603e-04</td><td>2.944636e-07</td><td>1.210964e-03</td><td>0.5571721</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CX-7086-01A</th><td>1.092963e-03</td><td>5.436330e-04</td><td>5.968087e-03</td><td>0.0325342298</td><td>0.013663174</td><td>5.613298e-03</td><td>6.030335e-05</td><td>2.351940e-03</td><td>2.253336e-03</td><td>1.266288e-06</td><td>1.168945e-05</td><td>0.9359061</td></tr>\n",
       "\t<tr><th scope=row>TCGA-CV-6935-11A</th><td>3.001992e-04</td><td>1.349548e-06</td><td>1.229702e-03</td><td>0.0272978745</td><td>0.009082117</td><td>3.730673e-02</td><td>4.052511e-04</td><td>5.923958e-04</td><td>2.227567e-05</td><td>6.677475e-04</td><td>2.754238e-04</td><td>0.9228189</td></tr>\n",
       "\t<tr><th scope=row>TCGA-P3-A6SW-01A</th><td>2.081898e-02</td><td>1.012480e-03</td><td>1.718169e-02</td><td>0.0502441143</td><td>0.087745865</td><td>4.834572e-02</td><td>2.908469e-03</td><td>9.189827e-06</td><td>1.350914e-02</td><td>7.265310e-07</td><td>1.708835e-02</td><td>0.7411353</td></tr>\n",
       "\t<tr><th scope=row>TCGA-HD-A6HZ-01A</th><td>8.469815e-03</td><td>1.001852e-02</td><td>4.467721e-03</td><td>0.0618777771</td><td>0.117164007</td><td>5.056453e-02</td><td>3.987480e-04</td><td>6.222276e-03</td><td>2.939265e-03</td><td>6.468833e-02</td><td>7.463512e-03</td><td>0.6657255</td></tr>\n",
       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "A data.frame: 546 × 12\n",
       "\\begin{tabular}{r|llllllllllll}\n",
       "  & B-cells & CD14-cells & CD8-cells & Endothelial & Fibroblast & Macrophage & Mast & NK-cells & pDC-cells & Tconv-cell & Treg-cells & tumor\\\\\n",
       "  & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl> & <dbl>\\\\\n",
       "\\hline\n",
       "\tTCGA-BB-4224-01A & 7.521237e-07 & 2.923092e-05 & 5.354050e-03 & 0.01899481 & 0.0190890154 & 1.667066e-02 & 1.783831e-04 & 4.943720e-03 & 1.032630e-03 & 6.065475e-03 & 3.046525e-04 & 0.92733662\\\\\n",
       "\tTCGA-H7-7774-01A & 2.474022e-04 & 1.642298e-05 & 6.565494e-03 & 0.01281692 & 0.0005243755 & 1.726243e-02 & 5.097020e-04 & 3.108857e-05 & 1.077549e-03 & 5.746715e-07 & 7.144899e-04 & 0.96023355\\\\\n",
       "\tTCGA-CV-6943-01A & 3.798463e-03 & 4.150265e-06 & 1.605742e-02 & 0.03871532 & 0.3809782307 & 1.322473e-01 & 7.728221e-04 & 7.299435e-07 & 2.718970e-03 & 2.688987e-07 & 1.883073e-03 & 0.42282326\\\\\n",
       "\tTCGA-CN-5374-01A & 5.620612e-03 & 2.203963e-03 & 1.479093e-02 & 0.03776265 & 0.0225637668 & 4.280413e-02 & 5.407611e-04 & 3.753455e-03 & 6.411098e-03 & 1.306061e-02 & 2.010434e-02 & 0.83038369\\\\\n",
       "\tTCGA-CQ-6227-01A & 2.847449e-07 & 1.274629e-06 & 1.352857e-06 & 0.08882163 & 0.2412421894 & 2.588085e-03 & 5.012126e-07 & 4.404987e-06 & 1.886387e-06 & 1.263138e-01 & 8.880127e-07 & 0.54102366\\\\\n",
       "\tTCGA-CV-6959-01A & 5.509745e-04 & 5.064183e-06 & 2.347650e-03 & 0.07513598 & 0.0868143815 & 2.803121e-02 & 3.417677e-07 & 3.955105e-03 & 1.351226e-05 & 1.119808e-01 & 5.516346e-06 & 0.69115943\\\\\n",
       "\tTCGA-F7-A61V-01A & 3.553009e-04 & 2.959224e-06 & 5.670216e-04 & 0.01864397 & 0.0239154964 & 3.346720e-06 & 4.332584e-07 & 1.042917e-03 & 1.550082e-03 & 5.635728e-02 & 2.310520e-03 & 0.89525067\\\\\n",
       "\tTCGA-CV-7413-01A & 3.587617e-05 & 1.339581e-06 & 6.724798e-03 & 0.01394333 & 0.2378109744 & 4.017224e-02 & 1.404934e-04 & 2.394474e-06 & 3.144350e-06 & 2.712702e-07 & 8.944177e-04 & 0.70027072\\\\\n",
       "\tTCGA-CV-7247-01A & 2.212088e-07 & 4.943082e-07 & 5.189074e-07 & 0.04870135 & 0.1485187444 & 7.200252e-07 & 1.806964e-07 & 5.455221e-07 & 3.395621e-07 & 1.370786e-01 & 4.846298e-07 & 0.66569777\\\\\n",
       "\tTCGA-CR-5249-01A & 8.501797e-03 & 4.055520e-03 & 1.371104e-02 & 0.05448906 & 0.0443576958 & 6.687471e-02 & 1.112755e-03 & 1.218416e-02 & 1.360507e-02 & 4.213912e-07 & 1.656411e-02 & 0.76454367\\\\\n",
       "\tTCGA-CQ-5331-01A & 5.733758e-04 & 3.486812e-06 & 9.742968e-03 & 0.05794117 & 0.0407393114 & 1.037272e-01 & 7.207214e-05 & 2.579330e-06 & 3.096985e-03 & 2.118289e-07 & 1.747090e-03 & 0.78235360\\\\\n",
       "\tTCGA-BB-8601-01A & 1.731479e-03 & 2.661071e-06 & 1.341848e-05 & 0.01377502 & 0.0077573390 & 2.344031e-06 & 7.369978e-04 & 1.203214e-03 & 3.643543e-06 & 1.299555e-06 & 8.569433e-06 & 0.97476402\\\\\n",
       "\tTCGA-CV-A45W-01A & 5.304755e-02 & 4.668449e-06 & 9.988465e-03 & 0.08118746 & 0.1003736426 & 8.972898e-02 & 7.019862e-04 & 4.999988e-03 & 6.153426e-03 & 7.634465e-07 & 8.800786e-03 & 0.64501228\\\\\n",
       "\tTCGA-CQ-7063-01A & 1.307273e-06 & 5.571277e-06 & 9.594590e-03 & 0.03522953 & 0.0157717693 & 1.071989e-01 & 6.160940e-04 & 1.747479e-05 & 2.668512e-03 & 6.395263e-07 & 9.372649e-04 & 0.82795833\\\\\n",
       "\tTCGA-CN-5373-01A & 6.849174e-05 & 1.352270e-05 & 1.085064e-02 & 0.02621258 & 0.2299667361 & 4.220190e-02 & 4.745499e-04 & 5.933012e-05 & 1.702080e-03 & 4.758960e-04 & 4.261388e-06 & 0.68797000\\\\\n",
       "\tTCGA-CV-A45T-01A & 4.805633e-03 & 8.073109e-06 & 2.740484e-02 & 0.04497311 & 0.0708530723 & 9.147216e-02 & 3.344305e-04 & 3.848610e-05 & 2.609326e-03 & 3.141035e-02 & 8.359557e-03 & 0.71773096\\\\\n",
       "\tTCGA-HD-A4C1-01A & 8.387271e-04 & 3.536181e-06 & 2.643809e-03 & 0.03405969 & 0.1035910946 & 5.817188e-03 & 5.490139e-07 & 3.467318e-03 & 7.022697e-04 & 4.463907e-07 & 2.087295e-05 & 0.84885450\\\\\n",
       "\tTCGA-CV-7438-11A & 1.778206e-03 & 9.754485e-05 & 9.765350e-03 & 0.01697486 & 0.0107794372 & 2.102821e-02 & 3.635568e-04 & 1.410328e-03 & 4.535285e-03 & 8.169412e-03 & 1.629515e-03 & 0.92346829\\\\\n",
       "\tTCGA-CV-5444-01A & 6.596345e-07 & 1.678087e-06 & 7.101029e-05 & 0.03731843 & 0.5265173593 & 1.093472e-01 & 7.530197e-07 & 1.981863e-06 & 5.822362e-04 & 4.695905e-02 & 1.555470e-05 & 0.27918413\\\\\n",
       "\tTCGA-BA-5556-01A & 1.173000e-03 & 1.222990e-03 & 1.506610e-02 & 0.05357313 & 0.0435331604 & 1.207894e-01 & 2.814119e-04 & 4.800570e-06 & 3.438276e-03 & 2.952937e-07 & 5.626280e-03 & 0.75529120\\\\\n",
       "\tTCGA-P3-A6SX-01A & 8.273896e-07 & 7.626181e-07 & 6.959556e-06 & 0.02133848 & 0.1287847942 & 8.543231e-07 & 6.660487e-05 & 9.999336e-04 & 1.528918e-06 & 1.748934e-02 & 5.326699e-06 & 0.83130458\\\\\n",
       "\tTCGA-CV-7242-11A & 1.401460e-04 & 6.212577e-06 & 5.814562e-03 & 0.02640606 & 0.0167292415 & 2.252533e-02 & 2.778300e-04 & 2.247169e-03 & 4.396532e-03 & 2.856326e-05 & 1.092367e-03 & 0.92033599\\\\\n",
       "\tTCGA-DQ-7592-01A & 1.026445e-06 & 1.200417e-04 & 5.320939e-03 & 0.03047937 & 0.1480833868 & 1.267932e-02 & 1.418083e-04 & 1.125114e-03 & 8.122057e-04 & 2.153864e-02 & 3.126022e-03 & 0.77657213\\\\\n",
       "\tTCGA-CV-6937-01A & 1.595918e-06 & 6.121839e-06 & 7.725410e-06 & 0.02371145 & 0.1790558892 & 6.051790e-02 & 8.751306e-05 & 2.242220e-05 & 2.877875e-03 & 6.920554e-07 & 1.605688e-03 & 0.73210512\\\\\n",
       "\tTCGA-QK-A8ZB-01A & 1.130815e-02 & 3.749270e-06 & 1.149054e-03 & 0.03265857 & 0.1401419183 & 8.707466e-03 & 5.001437e-04 & 7.590702e-03 & 1.466250e-03 & 4.915362e-07 & 5.090307e-04 & 0.79596447\\\\\n",
       "\tTCGA-CV-7432-01A & 5.053822e-07 & 4.289658e-06 & 1.538838e-04 & 0.01995220 & 0.0278294623 & 3.079319e-03 & 1.938185e-04 & 1.774354e-03 & 3.044177e-04 & 5.025951e-07 & 9.925769e-04 & 0.94571467\\\\\n",
       "\tTCGA-CV-7089-01A & 1.101232e-05 & 6.832658e-06 & 4.987475e-03 & 0.04590122 & 0.0174213920 & 1.222554e-02 & 7.491191e-04 & 1.776548e-03 & 8.436417e-04 & 4.626392e-07 & 1.076935e-03 & 0.91499981\\\\\n",
       "\tTCGA-CV-6939-11A & 1.534907e-07 & 1.507802e-07 & 1.420393e-07 & 0.01853427 & 0.0396254273 & 2.021104e-07 & 1.071993e-07 & 1.505424e-07 & 1.602020e-07 & 8.779284e-01 & 1.391324e-07 & 0.06391068\\\\\n",
       "\tTCGA-BA-4075-01A & 9.156259e-07 & 3.094603e-06 & 1.469122e-03 & 0.02971568 & 0.0459568350 & 3.187023e-02 & 4.420085e-05 & 9.539326e-03 & 2.148848e-05 & 4.980788e-03 & 1.378718e-03 & 0.87501961\\\\\n",
       "\tTCGA-T3-A92M-01A & 5.053911e-03 & 4.321249e-06 & 4.535910e-03 & 0.02452715 & 0.3363094290 & 7.850835e-02 & 2.093600e-04 & 3.436222e-03 & 7.437517e-04 & 4.086668e-07 & 6.457165e-03 & 0.54021403\\\\\n",
       "\t⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮\\\\\n",
       "\tTCGA-CV-7430-01A & 2.510364e-05 & 3.829535e-06 & 9.251480e-04 & 0.0220002455 & 0.021582735 & 5.593641e-04 & 1.467724e-04 & 2.426159e-03 & 2.901787e-05 & 7.895697e-07 & 6.417269e-06 & 0.9522944\\\\\n",
       "\tTCGA-D6-A74Q-01A & 7.791500e-03 & 3.423638e-05 & 3.396870e-03 & 0.0272028640 & 0.112548057 & 3.924812e-03 & 3.830402e-03 & 1.229835e-02 & 5.718750e-03 & 8.259003e-07 & 8.751835e-03 & 0.8145015\\\\\n",
       "\tTCGA-CV-7255-01A & 1.095024e-06 & 6.808349e-07 & 1.552601e-04 & 0.0437404879 & 0.029518875 & 7.154988e-07 & 2.181712e-05 & 1.436786e-03 & 4.695111e-07 & 1.604425e-02 & 5.681043e-04 & 0.9085115\\\\\n",
       "\tTCGA-CQ-6223-01A & 8.026109e-04 & 3.619042e-05 & 4.574028e-03 & 0.0106591300 & 0.018397980 & 1.391535e-02 & 8.635799e-04 & 2.450946e-03 & 1.685840e-03 & 3.876277e-07 & 8.657860e-04 & 0.9457482\\\\\n",
       "\tTCGA-CV-A460-01A & 6.520934e-03 & 2.105745e-02 & 1.550624e-02 & 0.0735747653 & 0.164898903 & 6.736238e-02 & 6.974457e-04 & 7.328822e-03 & 6.324749e-03 & 6.629139e-07 & 6.425260e-03 & 0.6303024\\\\\n",
       "\tTCGA-CV-7261-01A & 4.028455e-03 & 7.093352e-06 & 1.264518e-03 & 0.0515304559 & 0.222022093 & 2.907047e-02 & 4.046752e-04 & 6.647187e-03 & 2.081536e-04 & 1.024530e-06 & 7.358057e-06 & 0.6848085\\\\\n",
       "\tTCGA-CN-4736-01A & 3.042112e-07 & 5.745673e-04 & 4.504487e-03 & 0.0493733818 & 0.203851719 & 1.121733e-01 & 2.797655e-07 & 2.977295e-06 & 3.094837e-04 & 1.835070e-01 & 2.201801e-03 & 0.4435007\\\\\n",
       "\tTCGA-CR-7404-01A & 8.109896e-03 & 1.245529e-03 & 1.678593e-02 & 0.0644535513 & 0.050124414 & 6.723222e-02 & 7.647812e-04 & 5.958792e-03 & 9.602612e-03 & 6.147691e-07 & 4.956443e-03 & 0.7707652\\\\\n",
       "\tTCGA-UF-A719-01A & 4.339135e-04 & 6.728553e-05 & 4.072791e-03 & 0.0356415653 & 0.024351152 & 3.394154e-03 & 3.964999e-05 & 4.026614e-03 & 9.811350e-04 & 9.032943e-05 & 2.117762e-03 & 0.9247836\\\\\n",
       "\tTCGA-CV-7236-01A & 2.022737e-04 & 1.901099e-06 & 1.387850e-05 & 0.0749498741 & 0.196991255 & 2.256574e-02 & 1.077066e-04 & 1.087603e-02 & 5.148918e-04 & 5.414749e-07 & 1.457108e-03 & 0.6923188\\\\\n",
       "\tTCGA-CV-6951-01A & 6.263061e-07 & 1.552862e-06 & 5.196739e-06 & 0.0125731713 & 0.080220851 & 1.689773e-03 & 6.550422e-04 & 1.306809e-04 & 7.414515e-05 & 4.729976e-02 & 3.337689e-06 & 0.8573459\\\\\n",
       "\tTCGA-CN-4728-01A & 6.582277e-04 & 3.371294e-06 & 4.450652e-03 & 0.0409370445 & 0.580468135 & 1.493368e-01 & 4.704836e-04 & 1.817814e-05 & 1.053649e-03 & 8.110333e-03 & 8.723386e-06 & 0.2144844\\\\\n",
       "\tTCGA-CV-7090-01A & 1.220777e-06 & 1.710834e-06 & 9.923544e-03 & 0.0689356737 & 0.249057663 & 6.615897e-02 & 2.877527e-04 & 4.511355e-03 & 7.086549e-05 & 2.993599e-07 & 9.706727e-05 & 0.6009539\\\\\n",
       "\tTCGA-CV-5979-01A & 5.814996e-07 & 2.301133e-06 & 7.191630e-03 & 0.0366240069 & 0.055552577 & 8.153458e-03 & 2.030841e-05 & 1.265226e-05 & 1.451474e-06 & 1.539655e-03 & 6.528483e-06 & 0.8908949\\\\\n",
       "\tTCGA-CQ-7069-01A & 1.175565e-06 & 2.642127e-06 & 8.358562e-03 & 0.0685432957 & 0.092959285 & 4.438142e-04 & 2.885009e-04 & 1.551036e-03 & 1.919992e-05 & 4.770939e-07 & 3.649764e-06 & 0.8278284\\\\\n",
       "\tTCGA-CN-4733-01A & 1.683155e-02 & 3.003044e-05 & 3.209453e-02 & 0.0972987967 & 0.285705707 & 1.685431e-01 & 1.672578e-03 & 3.460009e-03 & 2.323855e-02 & 1.686708e-02 & 8.573240e-03 & 0.3456848\\\\\n",
       "\tTCGA-CR-7390-01A & 2.065906e-05 & 1.787416e-06 & 7.774182e-06 & 0.0303656461 & 0.213920663 & 5.872467e-03 & 1.662505e-04 & 4.445526e-03 & 1.206895e-06 & 4.301343e-07 & 2.897329e-06 & 0.7451947\\\\\n",
       "\tTCGA-CV-A45X-01A & 4.567125e-05 & 6.166679e-06 & 1.847638e-03 & 0.0168099053 & 0.020004646 & 5.965875e-03 & 6.785496e-05 & 2.811138e-03 & 7.777258e-04 & 1.110329e-06 & 2.337816e-03 & 0.9493245\\\\\n",
       "\tTCGA-IQ-A6SH-01A & 9.626654e-04 & 2.418314e-05 & 7.269247e-03 & 0.0275554746 & 0.036440188 & 2.994372e-02 & 3.226413e-04 & 2.186796e-04 & 6.891492e-04 & 6.732549e-07 & 4.617974e-04 & 0.8961116\\\\\n",
       "\tTCGA-CV-6962-11A & 7.001844e-04 & 2.465428e-06 & 2.058588e-03 & 0.0287513385 & 0.037895283 & 4.559363e-03 & 4.198810e-04 & 1.897996e-03 & 2.243572e-03 & 1.048223e-04 & 8.891491e-04 & 0.9204774\\\\\n",
       "\tTCGA-CV-6960-11A & 2.643422e-05 & 3.702759e-06 & 1.202062e-03 & 0.0269575408 & 0.011001313 & 1.009368e-02 & 8.802926e-04 & 1.108602e-03 & 1.712646e-03 & 9.216748e-05 & 1.391011e-05 & 0.9469077\\\\\n",
       "\tTCGA-CV-A464-01A & 4.868739e-07 & 3.738478e-06 & 4.140700e-03 & 0.0492785176 & 0.365218102 & 1.037947e-02 & 8.347710e-05 & 6.623413e-06 & 2.516128e-03 & 7.221133e-02 & 5.425213e-04 & 0.4956189\\\\\n",
       "\tTCGA-C9-A47Z-01A & 1.794621e-05 & 2.189491e-05 & 1.659820e-03 & 0.0127283062 & 0.012865199 & 2.924776e-03 & 2.586389e-05 & 1.184250e-03 & 1.264258e-04 & 6.463346e-03 & 1.646568e-04 & 0.9618175\\\\\n",
       "\tTCGA-CN-6010-01A & 6.985689e-03 & 1.609571e-06 & 2.066856e-05 & 0.0686872297 & 0.092435372 & 1.028982e-01 & 8.159275e-04 & 7.523645e-06 & 1.319148e-06 & 1.907857e-02 & 4.058772e-06 & 0.7090638\\\\\n",
       "\tTCGA-WA-A7GZ-11A & 1.593409e-07 & 1.963554e-07 & 1.654410e-07 & 0.0005308816 & 0.011840187 & 2.209323e-07 & 1.398135e-07 & 1.826388e-07 & 2.031713e-07 & 7.626023e-01 & 1.732265e-07 & 0.2250252\\\\\n",
       "\tTCGA-CV-7235-01A & 3.909553e-07 & 6.524707e-04 & 1.192152e-02 & 0.0517575839 & 0.331035588 & 4.341405e-02 & 3.739575e-04 & 1.721061e-03 & 7.400603e-04 & 2.944636e-07 & 1.210964e-03 & 0.5571721\\\\\n",
       "\tTCGA-CX-7086-01A & 1.092963e-03 & 5.436330e-04 & 5.968087e-03 & 0.0325342298 & 0.013663174 & 5.613298e-03 & 6.030335e-05 & 2.351940e-03 & 2.253336e-03 & 1.266288e-06 & 1.168945e-05 & 0.9359061\\\\\n",
       "\tTCGA-CV-6935-11A & 3.001992e-04 & 1.349548e-06 & 1.229702e-03 & 0.0272978745 & 0.009082117 & 3.730673e-02 & 4.052511e-04 & 5.923958e-04 & 2.227567e-05 & 6.677475e-04 & 2.754238e-04 & 0.9228189\\\\\n",
       "\tTCGA-P3-A6SW-01A & 2.081898e-02 & 1.012480e-03 & 1.718169e-02 & 0.0502441143 & 0.087745865 & 4.834572e-02 & 2.908469e-03 & 9.189827e-06 & 1.350914e-02 & 7.265310e-07 & 1.708835e-02 & 0.7411353\\\\\n",
       "\tTCGA-HD-A6HZ-01A & 8.469815e-03 & 1.001852e-02 & 4.467721e-03 & 0.0618777771 & 0.117164007 & 5.056453e-02 & 3.987480e-04 & 6.222276e-03 & 2.939265e-03 & 6.468833e-02 & 7.463512e-03 & 0.6657255\\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "A data.frame: 546 × 12\n",
       "\n",
       "| <!--/--> | B-cells &lt;dbl&gt; | CD14-cells &lt;dbl&gt; | CD8-cells &lt;dbl&gt; | Endothelial &lt;dbl&gt; | Fibroblast &lt;dbl&gt; | Macrophage &lt;dbl&gt; | Mast &lt;dbl&gt; | NK-cells &lt;dbl&gt; | pDC-cells &lt;dbl&gt; | Tconv-cell &lt;dbl&gt; | Treg-cells &lt;dbl&gt; | tumor &lt;dbl&gt; |\n",
       "|---|---|---|---|---|---|---|---|---|---|---|---|---|\n",
       "| TCGA-BB-4224-01A | 7.521237e-07 | 2.923092e-05 | 5.354050e-03 | 0.01899481 | 0.0190890154 | 1.667066e-02 | 1.783831e-04 | 4.943720e-03 | 1.032630e-03 | 6.065475e-03 | 3.046525e-04 | 0.92733662 |\n",
       "| TCGA-H7-7774-01A | 2.474022e-04 | 1.642298e-05 | 6.565494e-03 | 0.01281692 | 0.0005243755 | 1.726243e-02 | 5.097020e-04 | 3.108857e-05 | 1.077549e-03 | 5.746715e-07 | 7.144899e-04 | 0.96023355 |\n",
       "| TCGA-CV-6943-01A | 3.798463e-03 | 4.150265e-06 | 1.605742e-02 | 0.03871532 | 0.3809782307 | 1.322473e-01 | 7.728221e-04 | 7.299435e-07 | 2.718970e-03 | 2.688987e-07 | 1.883073e-03 | 0.42282326 |\n",
       "| TCGA-CN-5374-01A | 5.620612e-03 | 2.203963e-03 | 1.479093e-02 | 0.03776265 | 0.0225637668 | 4.280413e-02 | 5.407611e-04 | 3.753455e-03 | 6.411098e-03 | 1.306061e-02 | 2.010434e-02 | 0.83038369 |\n",
       "| TCGA-CQ-6227-01A | 2.847449e-07 | 1.274629e-06 | 1.352857e-06 | 0.08882163 | 0.2412421894 | 2.588085e-03 | 5.012126e-07 | 4.404987e-06 | 1.886387e-06 | 1.263138e-01 | 8.880127e-07 | 0.54102366 |\n",
       "| TCGA-CV-6959-01A | 5.509745e-04 | 5.064183e-06 | 2.347650e-03 | 0.07513598 | 0.0868143815 | 2.803121e-02 | 3.417677e-07 | 3.955105e-03 | 1.351226e-05 | 1.119808e-01 | 5.516346e-06 | 0.69115943 |\n",
       "| TCGA-F7-A61V-01A | 3.553009e-04 | 2.959224e-06 | 5.670216e-04 | 0.01864397 | 0.0239154964 | 3.346720e-06 | 4.332584e-07 | 1.042917e-03 | 1.550082e-03 | 5.635728e-02 | 2.310520e-03 | 0.89525067 |\n",
       "| TCGA-CV-7413-01A | 3.587617e-05 | 1.339581e-06 | 6.724798e-03 | 0.01394333 | 0.2378109744 | 4.017224e-02 | 1.404934e-04 | 2.394474e-06 | 3.144350e-06 | 2.712702e-07 | 8.944177e-04 | 0.70027072 |\n",
       "| TCGA-CV-7247-01A | 2.212088e-07 | 4.943082e-07 | 5.189074e-07 | 0.04870135 | 0.1485187444 | 7.200252e-07 | 1.806964e-07 | 5.455221e-07 | 3.395621e-07 | 1.370786e-01 | 4.846298e-07 | 0.66569777 |\n",
       "| TCGA-CR-5249-01A | 8.501797e-03 | 4.055520e-03 | 1.371104e-02 | 0.05448906 | 0.0443576958 | 6.687471e-02 | 1.112755e-03 | 1.218416e-02 | 1.360507e-02 | 4.213912e-07 | 1.656411e-02 | 0.76454367 |\n",
       "| TCGA-CQ-5331-01A | 5.733758e-04 | 3.486812e-06 | 9.742968e-03 | 0.05794117 | 0.0407393114 | 1.037272e-01 | 7.207214e-05 | 2.579330e-06 | 3.096985e-03 | 2.118289e-07 | 1.747090e-03 | 0.78235360 |\n",
       "| TCGA-BB-8601-01A | 1.731479e-03 | 2.661071e-06 | 1.341848e-05 | 0.01377502 | 0.0077573390 | 2.344031e-06 | 7.369978e-04 | 1.203214e-03 | 3.643543e-06 | 1.299555e-06 | 8.569433e-06 | 0.97476402 |\n",
       "| TCGA-CV-A45W-01A | 5.304755e-02 | 4.668449e-06 | 9.988465e-03 | 0.08118746 | 0.1003736426 | 8.972898e-02 | 7.019862e-04 | 4.999988e-03 | 6.153426e-03 | 7.634465e-07 | 8.800786e-03 | 0.64501228 |\n",
       "| TCGA-CQ-7063-01A | 1.307273e-06 | 5.571277e-06 | 9.594590e-03 | 0.03522953 | 0.0157717693 | 1.071989e-01 | 6.160940e-04 | 1.747479e-05 | 2.668512e-03 | 6.395263e-07 | 9.372649e-04 | 0.82795833 |\n",
       "| TCGA-CN-5373-01A | 6.849174e-05 | 1.352270e-05 | 1.085064e-02 | 0.02621258 | 0.2299667361 | 4.220190e-02 | 4.745499e-04 | 5.933012e-05 | 1.702080e-03 | 4.758960e-04 | 4.261388e-06 | 0.68797000 |\n",
       "| TCGA-CV-A45T-01A | 4.805633e-03 | 8.073109e-06 | 2.740484e-02 | 0.04497311 | 0.0708530723 | 9.147216e-02 | 3.344305e-04 | 3.848610e-05 | 2.609326e-03 | 3.141035e-02 | 8.359557e-03 | 0.71773096 |\n",
       "| TCGA-HD-A4C1-01A | 8.387271e-04 | 3.536181e-06 | 2.643809e-03 | 0.03405969 | 0.1035910946 | 5.817188e-03 | 5.490139e-07 | 3.467318e-03 | 7.022697e-04 | 4.463907e-07 | 2.087295e-05 | 0.84885450 |\n",
       "| TCGA-CV-7438-11A | 1.778206e-03 | 9.754485e-05 | 9.765350e-03 | 0.01697486 | 0.0107794372 | 2.102821e-02 | 3.635568e-04 | 1.410328e-03 | 4.535285e-03 | 8.169412e-03 | 1.629515e-03 | 0.92346829 |\n",
       "| TCGA-CV-5444-01A | 6.596345e-07 | 1.678087e-06 | 7.101029e-05 | 0.03731843 | 0.5265173593 | 1.093472e-01 | 7.530197e-07 | 1.981863e-06 | 5.822362e-04 | 4.695905e-02 | 1.555470e-05 | 0.27918413 |\n",
       "| TCGA-BA-5556-01A | 1.173000e-03 | 1.222990e-03 | 1.506610e-02 | 0.05357313 | 0.0435331604 | 1.207894e-01 | 2.814119e-04 | 4.800570e-06 | 3.438276e-03 | 2.952937e-07 | 5.626280e-03 | 0.75529120 |\n",
       "| TCGA-P3-A6SX-01A | 8.273896e-07 | 7.626181e-07 | 6.959556e-06 | 0.02133848 | 0.1287847942 | 8.543231e-07 | 6.660487e-05 | 9.999336e-04 | 1.528918e-06 | 1.748934e-02 | 5.326699e-06 | 0.83130458 |\n",
       "| TCGA-CV-7242-11A | 1.401460e-04 | 6.212577e-06 | 5.814562e-03 | 0.02640606 | 0.0167292415 | 2.252533e-02 | 2.778300e-04 | 2.247169e-03 | 4.396532e-03 | 2.856326e-05 | 1.092367e-03 | 0.92033599 |\n",
       "| TCGA-DQ-7592-01A | 1.026445e-06 | 1.200417e-04 | 5.320939e-03 | 0.03047937 | 0.1480833868 | 1.267932e-02 | 1.418083e-04 | 1.125114e-03 | 8.122057e-04 | 2.153864e-02 | 3.126022e-03 | 0.77657213 |\n",
       "| TCGA-CV-6937-01A | 1.595918e-06 | 6.121839e-06 | 7.725410e-06 | 0.02371145 | 0.1790558892 | 6.051790e-02 | 8.751306e-05 | 2.242220e-05 | 2.877875e-03 | 6.920554e-07 | 1.605688e-03 | 0.73210512 |\n",
       "| TCGA-QK-A8ZB-01A | 1.130815e-02 | 3.749270e-06 | 1.149054e-03 | 0.03265857 | 0.1401419183 | 8.707466e-03 | 5.001437e-04 | 7.590702e-03 | 1.466250e-03 | 4.915362e-07 | 5.090307e-04 | 0.79596447 |\n",
       "| TCGA-CV-7432-01A | 5.053822e-07 | 4.289658e-06 | 1.538838e-04 | 0.01995220 | 0.0278294623 | 3.079319e-03 | 1.938185e-04 | 1.774354e-03 | 3.044177e-04 | 5.025951e-07 | 9.925769e-04 | 0.94571467 |\n",
       "| TCGA-CV-7089-01A | 1.101232e-05 | 6.832658e-06 | 4.987475e-03 | 0.04590122 | 0.0174213920 | 1.222554e-02 | 7.491191e-04 | 1.776548e-03 | 8.436417e-04 | 4.626392e-07 | 1.076935e-03 | 0.91499981 |\n",
       "| TCGA-CV-6939-11A | 1.534907e-07 | 1.507802e-07 | 1.420393e-07 | 0.01853427 | 0.0396254273 | 2.021104e-07 | 1.071993e-07 | 1.505424e-07 | 1.602020e-07 | 8.779284e-01 | 1.391324e-07 | 0.06391068 |\n",
       "| TCGA-BA-4075-01A | 9.156259e-07 | 3.094603e-06 | 1.469122e-03 | 0.02971568 | 0.0459568350 | 3.187023e-02 | 4.420085e-05 | 9.539326e-03 | 2.148848e-05 | 4.980788e-03 | 1.378718e-03 | 0.87501961 |\n",
       "| TCGA-T3-A92M-01A | 5.053911e-03 | 4.321249e-06 | 4.535910e-03 | 0.02452715 | 0.3363094290 | 7.850835e-02 | 2.093600e-04 | 3.436222e-03 | 7.437517e-04 | 4.086668e-07 | 6.457165e-03 | 0.54021403 |\n",
       "| ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ |\n",
       "| TCGA-CV-7430-01A | 2.510364e-05 | 3.829535e-06 | 9.251480e-04 | 0.0220002455 | 0.021582735 | 5.593641e-04 | 1.467724e-04 | 2.426159e-03 | 2.901787e-05 | 7.895697e-07 | 6.417269e-06 | 0.9522944 |\n",
       "| TCGA-D6-A74Q-01A | 7.791500e-03 | 3.423638e-05 | 3.396870e-03 | 0.0272028640 | 0.112548057 | 3.924812e-03 | 3.830402e-03 | 1.229835e-02 | 5.718750e-03 | 8.259003e-07 | 8.751835e-03 | 0.8145015 |\n",
       "| TCGA-CV-7255-01A | 1.095024e-06 | 6.808349e-07 | 1.552601e-04 | 0.0437404879 | 0.029518875 | 7.154988e-07 | 2.181712e-05 | 1.436786e-03 | 4.695111e-07 | 1.604425e-02 | 5.681043e-04 | 0.9085115 |\n",
       "| TCGA-CQ-6223-01A | 8.026109e-04 | 3.619042e-05 | 4.574028e-03 | 0.0106591300 | 0.018397980 | 1.391535e-02 | 8.635799e-04 | 2.450946e-03 | 1.685840e-03 | 3.876277e-07 | 8.657860e-04 | 0.9457482 |\n",
       "| TCGA-CV-A460-01A | 6.520934e-03 | 2.105745e-02 | 1.550624e-02 | 0.0735747653 | 0.164898903 | 6.736238e-02 | 6.974457e-04 | 7.328822e-03 | 6.324749e-03 | 6.629139e-07 | 6.425260e-03 | 0.6303024 |\n",
       "| TCGA-CV-7261-01A | 4.028455e-03 | 7.093352e-06 | 1.264518e-03 | 0.0515304559 | 0.222022093 | 2.907047e-02 | 4.046752e-04 | 6.647187e-03 | 2.081536e-04 | 1.024530e-06 | 7.358057e-06 | 0.6848085 |\n",
       "| TCGA-CN-4736-01A | 3.042112e-07 | 5.745673e-04 | 4.504487e-03 | 0.0493733818 | 0.203851719 | 1.121733e-01 | 2.797655e-07 | 2.977295e-06 | 3.094837e-04 | 1.835070e-01 | 2.201801e-03 | 0.4435007 |\n",
       "| TCGA-CR-7404-01A | 8.109896e-03 | 1.245529e-03 | 1.678593e-02 | 0.0644535513 | 0.050124414 | 6.723222e-02 | 7.647812e-04 | 5.958792e-03 | 9.602612e-03 | 6.147691e-07 | 4.956443e-03 | 0.7707652 |\n",
       "| TCGA-UF-A719-01A | 4.339135e-04 | 6.728553e-05 | 4.072791e-03 | 0.0356415653 | 0.024351152 | 3.394154e-03 | 3.964999e-05 | 4.026614e-03 | 9.811350e-04 | 9.032943e-05 | 2.117762e-03 | 0.9247836 |\n",
       "| TCGA-CV-7236-01A | 2.022737e-04 | 1.901099e-06 | 1.387850e-05 | 0.0749498741 | 0.196991255 | 2.256574e-02 | 1.077066e-04 | 1.087603e-02 | 5.148918e-04 | 5.414749e-07 | 1.457108e-03 | 0.6923188 |\n",
       "| TCGA-CV-6951-01A | 6.263061e-07 | 1.552862e-06 | 5.196739e-06 | 0.0125731713 | 0.080220851 | 1.689773e-03 | 6.550422e-04 | 1.306809e-04 | 7.414515e-05 | 4.729976e-02 | 3.337689e-06 | 0.8573459 |\n",
       "| TCGA-CN-4728-01A | 6.582277e-04 | 3.371294e-06 | 4.450652e-03 | 0.0409370445 | 0.580468135 | 1.493368e-01 | 4.704836e-04 | 1.817814e-05 | 1.053649e-03 | 8.110333e-03 | 8.723386e-06 | 0.2144844 |\n",
       "| TCGA-CV-7090-01A | 1.220777e-06 | 1.710834e-06 | 9.923544e-03 | 0.0689356737 | 0.249057663 | 6.615897e-02 | 2.877527e-04 | 4.511355e-03 | 7.086549e-05 | 2.993599e-07 | 9.706727e-05 | 0.6009539 |\n",
       "| TCGA-CV-5979-01A | 5.814996e-07 | 2.301133e-06 | 7.191630e-03 | 0.0366240069 | 0.055552577 | 8.153458e-03 | 2.030841e-05 | 1.265226e-05 | 1.451474e-06 | 1.539655e-03 | 6.528483e-06 | 0.8908949 |\n",
       "| TCGA-CQ-7069-01A | 1.175565e-06 | 2.642127e-06 | 8.358562e-03 | 0.0685432957 | 0.092959285 | 4.438142e-04 | 2.885009e-04 | 1.551036e-03 | 1.919992e-05 | 4.770939e-07 | 3.649764e-06 | 0.8278284 |\n",
       "| TCGA-CN-4733-01A | 1.683155e-02 | 3.003044e-05 | 3.209453e-02 | 0.0972987967 | 0.285705707 | 1.685431e-01 | 1.672578e-03 | 3.460009e-03 | 2.323855e-02 | 1.686708e-02 | 8.573240e-03 | 0.3456848 |\n",
       "| TCGA-CR-7390-01A | 2.065906e-05 | 1.787416e-06 | 7.774182e-06 | 0.0303656461 | 0.213920663 | 5.872467e-03 | 1.662505e-04 | 4.445526e-03 | 1.206895e-06 | 4.301343e-07 | 2.897329e-06 | 0.7451947 |\n",
       "| TCGA-CV-A45X-01A | 4.567125e-05 | 6.166679e-06 | 1.847638e-03 | 0.0168099053 | 0.020004646 | 5.965875e-03 | 6.785496e-05 | 2.811138e-03 | 7.777258e-04 | 1.110329e-06 | 2.337816e-03 | 0.9493245 |\n",
       "| TCGA-IQ-A6SH-01A | 9.626654e-04 | 2.418314e-05 | 7.269247e-03 | 0.0275554746 | 0.036440188 | 2.994372e-02 | 3.226413e-04 | 2.186796e-04 | 6.891492e-04 | 6.732549e-07 | 4.617974e-04 | 0.8961116 |\n",
       "| TCGA-CV-6962-11A | 7.001844e-04 | 2.465428e-06 | 2.058588e-03 | 0.0287513385 | 0.037895283 | 4.559363e-03 | 4.198810e-04 | 1.897996e-03 | 2.243572e-03 | 1.048223e-04 | 8.891491e-04 | 0.9204774 |\n",
       "| TCGA-CV-6960-11A | 2.643422e-05 | 3.702759e-06 | 1.202062e-03 | 0.0269575408 | 0.011001313 | 1.009368e-02 | 8.802926e-04 | 1.108602e-03 | 1.712646e-03 | 9.216748e-05 | 1.391011e-05 | 0.9469077 |\n",
       "| TCGA-CV-A464-01A | 4.868739e-07 | 3.738478e-06 | 4.140700e-03 | 0.0492785176 | 0.365218102 | 1.037947e-02 | 8.347710e-05 | 6.623413e-06 | 2.516128e-03 | 7.221133e-02 | 5.425213e-04 | 0.4956189 |\n",
       "| TCGA-C9-A47Z-01A | 1.794621e-05 | 2.189491e-05 | 1.659820e-03 | 0.0127283062 | 0.012865199 | 2.924776e-03 | 2.586389e-05 | 1.184250e-03 | 1.264258e-04 | 6.463346e-03 | 1.646568e-04 | 0.9618175 |\n",
       "| TCGA-CN-6010-01A | 6.985689e-03 | 1.609571e-06 | 2.066856e-05 | 0.0686872297 | 0.092435372 | 1.028982e-01 | 8.159275e-04 | 7.523645e-06 | 1.319148e-06 | 1.907857e-02 | 4.058772e-06 | 0.7090638 |\n",
       "| TCGA-WA-A7GZ-11A | 1.593409e-07 | 1.963554e-07 | 1.654410e-07 | 0.0005308816 | 0.011840187 | 2.209323e-07 | 1.398135e-07 | 1.826388e-07 | 2.031713e-07 | 7.626023e-01 | 1.732265e-07 | 0.2250252 |\n",
       "| TCGA-CV-7235-01A | 3.909553e-07 | 6.524707e-04 | 1.192152e-02 | 0.0517575839 | 0.331035588 | 4.341405e-02 | 3.739575e-04 | 1.721061e-03 | 7.400603e-04 | 2.944636e-07 | 1.210964e-03 | 0.5571721 |\n",
       "| TCGA-CX-7086-01A | 1.092963e-03 | 5.436330e-04 | 5.968087e-03 | 0.0325342298 | 0.013663174 | 5.613298e-03 | 6.030335e-05 | 2.351940e-03 | 2.253336e-03 | 1.266288e-06 | 1.168945e-05 | 0.9359061 |\n",
       "| TCGA-CV-6935-11A | 3.001992e-04 | 1.349548e-06 | 1.229702e-03 | 0.0272978745 | 0.009082117 | 3.730673e-02 | 4.052511e-04 | 5.923958e-04 | 2.227567e-05 | 6.677475e-04 | 2.754238e-04 | 0.9228189 |\n",
       "| TCGA-P3-A6SW-01A | 2.081898e-02 | 1.012480e-03 | 1.718169e-02 | 0.0502441143 | 0.087745865 | 4.834572e-02 | 2.908469e-03 | 9.189827e-06 | 1.350914e-02 | 7.265310e-07 | 1.708835e-02 | 0.7411353 |\n",
       "| TCGA-HD-A6HZ-01A | 8.469815e-03 | 1.001852e-02 | 4.467721e-03 | 0.0618777771 | 0.117164007 | 5.056453e-02 | 3.987480e-04 | 6.222276e-03 | 2.939265e-03 | 6.468833e-02 | 7.463512e-03 | 0.6657255 |\n",
       "\n"
      ],
      "text/plain": [
       "                 B-cells      CD14-cells   CD8-cells    Endothelial \n",
       "TCGA-BB-4224-01A 7.521237e-07 2.923092e-05 5.354050e-03 0.01899481  \n",
       "TCGA-H7-7774-01A 2.474022e-04 1.642298e-05 6.565494e-03 0.01281692  \n",
       "TCGA-CV-6943-01A 3.798463e-03 4.150265e-06 1.605742e-02 0.03871532  \n",
       "TCGA-CN-5374-01A 5.620612e-03 2.203963e-03 1.479093e-02 0.03776265  \n",
       "TCGA-CQ-6227-01A 2.847449e-07 1.274629e-06 1.352857e-06 0.08882163  \n",
       "TCGA-CV-6959-01A 5.509745e-04 5.064183e-06 2.347650e-03 0.07513598  \n",
       "TCGA-F7-A61V-01A 3.553009e-04 2.959224e-06 5.670216e-04 0.01864397  \n",
       "TCGA-CV-7413-01A 3.587617e-05 1.339581e-06 6.724798e-03 0.01394333  \n",
       "TCGA-CV-7247-01A 2.212088e-07 4.943082e-07 5.189074e-07 0.04870135  \n",
       "TCGA-CR-5249-01A 8.501797e-03 4.055520e-03 1.371104e-02 0.05448906  \n",
       "TCGA-CQ-5331-01A 5.733758e-04 3.486812e-06 9.742968e-03 0.05794117  \n",
       "TCGA-BB-8601-01A 1.731479e-03 2.661071e-06 1.341848e-05 0.01377502  \n",
       "TCGA-CV-A45W-01A 5.304755e-02 4.668449e-06 9.988465e-03 0.08118746  \n",
       "TCGA-CQ-7063-01A 1.307273e-06 5.571277e-06 9.594590e-03 0.03522953  \n",
       "TCGA-CN-5373-01A 6.849174e-05 1.352270e-05 1.085064e-02 0.02621258  \n",
       "TCGA-CV-A45T-01A 4.805633e-03 8.073109e-06 2.740484e-02 0.04497311  \n",
       "TCGA-HD-A4C1-01A 8.387271e-04 3.536181e-06 2.643809e-03 0.03405969  \n",
       "TCGA-CV-7438-11A 1.778206e-03 9.754485e-05 9.765350e-03 0.01697486  \n",
       "TCGA-CV-5444-01A 6.596345e-07 1.678087e-06 7.101029e-05 0.03731843  \n",
       "TCGA-BA-5556-01A 1.173000e-03 1.222990e-03 1.506610e-02 0.05357313  \n",
       "TCGA-P3-A6SX-01A 8.273896e-07 7.626181e-07 6.959556e-06 0.02133848  \n",
       "TCGA-CV-7242-11A 1.401460e-04 6.212577e-06 5.814562e-03 0.02640606  \n",
       "TCGA-DQ-7592-01A 1.026445e-06 1.200417e-04 5.320939e-03 0.03047937  \n",
       "TCGA-CV-6937-01A 1.595918e-06 6.121839e-06 7.725410e-06 0.02371145  \n",
       "TCGA-QK-A8ZB-01A 1.130815e-02 3.749270e-06 1.149054e-03 0.03265857  \n",
       "TCGA-CV-7432-01A 5.053822e-07 4.289658e-06 1.538838e-04 0.01995220  \n",
       "TCGA-CV-7089-01A 1.101232e-05 6.832658e-06 4.987475e-03 0.04590122  \n",
       "TCGA-CV-6939-11A 1.534907e-07 1.507802e-07 1.420393e-07 0.01853427  \n",
       "TCGA-BA-4075-01A 9.156259e-07 3.094603e-06 1.469122e-03 0.02971568  \n",
       "TCGA-T3-A92M-01A 5.053911e-03 4.321249e-06 4.535910e-03 0.02452715  \n",
       "⋮                ⋮            ⋮            ⋮            ⋮           \n",
       "TCGA-CV-7430-01A 2.510364e-05 3.829535e-06 9.251480e-04 0.0220002455\n",
       "TCGA-D6-A74Q-01A 7.791500e-03 3.423638e-05 3.396870e-03 0.0272028640\n",
       "TCGA-CV-7255-01A 1.095024e-06 6.808349e-07 1.552601e-04 0.0437404879\n",
       "TCGA-CQ-6223-01A 8.026109e-04 3.619042e-05 4.574028e-03 0.0106591300\n",
       "TCGA-CV-A460-01A 6.520934e-03 2.105745e-02 1.550624e-02 0.0735747653\n",
       "TCGA-CV-7261-01A 4.028455e-03 7.093352e-06 1.264518e-03 0.0515304559\n",
       "TCGA-CN-4736-01A 3.042112e-07 5.745673e-04 4.504487e-03 0.0493733818\n",
       "TCGA-CR-7404-01A 8.109896e-03 1.245529e-03 1.678593e-02 0.0644535513\n",
       "TCGA-UF-A719-01A 4.339135e-04 6.728553e-05 4.072791e-03 0.0356415653\n",
       "TCGA-CV-7236-01A 2.022737e-04 1.901099e-06 1.387850e-05 0.0749498741\n",
       "TCGA-CV-6951-01A 6.263061e-07 1.552862e-06 5.196739e-06 0.0125731713\n",
       "TCGA-CN-4728-01A 6.582277e-04 3.371294e-06 4.450652e-03 0.0409370445\n",
       "TCGA-CV-7090-01A 1.220777e-06 1.710834e-06 9.923544e-03 0.0689356737\n",
       "TCGA-CV-5979-01A 5.814996e-07 2.301133e-06 7.191630e-03 0.0366240069\n",
       "TCGA-CQ-7069-01A 1.175565e-06 2.642127e-06 8.358562e-03 0.0685432957\n",
       "TCGA-CN-4733-01A 1.683155e-02 3.003044e-05 3.209453e-02 0.0972987967\n",
       "TCGA-CR-7390-01A 2.065906e-05 1.787416e-06 7.774182e-06 0.0303656461\n",
       "TCGA-CV-A45X-01A 4.567125e-05 6.166679e-06 1.847638e-03 0.0168099053\n",
       "TCGA-IQ-A6SH-01A 9.626654e-04 2.418314e-05 7.269247e-03 0.0275554746\n",
       "TCGA-CV-6962-11A 7.001844e-04 2.465428e-06 2.058588e-03 0.0287513385\n",
       "TCGA-CV-6960-11A 2.643422e-05 3.702759e-06 1.202062e-03 0.0269575408\n",
       "TCGA-CV-A464-01A 4.868739e-07 3.738478e-06 4.140700e-03 0.0492785176\n",
       "TCGA-C9-A47Z-01A 1.794621e-05 2.189491e-05 1.659820e-03 0.0127283062\n",
       "TCGA-CN-6010-01A 6.985689e-03 1.609571e-06 2.066856e-05 0.0686872297\n",
       "TCGA-WA-A7GZ-11A 1.593409e-07 1.963554e-07 1.654410e-07 0.0005308816\n",
       "TCGA-CV-7235-01A 3.909553e-07 6.524707e-04 1.192152e-02 0.0517575839\n",
       "TCGA-CX-7086-01A 1.092963e-03 5.436330e-04 5.968087e-03 0.0325342298\n",
       "TCGA-CV-6935-11A 3.001992e-04 1.349548e-06 1.229702e-03 0.0272978745\n",
       "TCGA-P3-A6SW-01A 2.081898e-02 1.012480e-03 1.718169e-02 0.0502441143\n",
       "TCGA-HD-A6HZ-01A 8.469815e-03 1.001852e-02 4.467721e-03 0.0618777771\n",
       "                 Fibroblast   Macrophage   Mast         NK-cells    \n",
       "TCGA-BB-4224-01A 0.0190890154 1.667066e-02 1.783831e-04 4.943720e-03\n",
       "TCGA-H7-7774-01A 0.0005243755 1.726243e-02 5.097020e-04 3.108857e-05\n",
       "TCGA-CV-6943-01A 0.3809782307 1.322473e-01 7.728221e-04 7.299435e-07\n",
       "TCGA-CN-5374-01A 0.0225637668 4.280413e-02 5.407611e-04 3.753455e-03\n",
       "TCGA-CQ-6227-01A 0.2412421894 2.588085e-03 5.012126e-07 4.404987e-06\n",
       "TCGA-CV-6959-01A 0.0868143815 2.803121e-02 3.417677e-07 3.955105e-03\n",
       "TCGA-F7-A61V-01A 0.0239154964 3.346720e-06 4.332584e-07 1.042917e-03\n",
       "TCGA-CV-7413-01A 0.2378109744 4.017224e-02 1.404934e-04 2.394474e-06\n",
       "TCGA-CV-7247-01A 0.1485187444 7.200252e-07 1.806964e-07 5.455221e-07\n",
       "TCGA-CR-5249-01A 0.0443576958 6.687471e-02 1.112755e-03 1.218416e-02\n",
       "TCGA-CQ-5331-01A 0.0407393114 1.037272e-01 7.207214e-05 2.579330e-06\n",
       "TCGA-BB-8601-01A 0.0077573390 2.344031e-06 7.369978e-04 1.203214e-03\n",
       "TCGA-CV-A45W-01A 0.1003736426 8.972898e-02 7.019862e-04 4.999988e-03\n",
       "TCGA-CQ-7063-01A 0.0157717693 1.071989e-01 6.160940e-04 1.747479e-05\n",
       "TCGA-CN-5373-01A 0.2299667361 4.220190e-02 4.745499e-04 5.933012e-05\n",
       "TCGA-CV-A45T-01A 0.0708530723 9.147216e-02 3.344305e-04 3.848610e-05\n",
       "TCGA-HD-A4C1-01A 0.1035910946 5.817188e-03 5.490139e-07 3.467318e-03\n",
       "TCGA-CV-7438-11A 0.0107794372 2.102821e-02 3.635568e-04 1.410328e-03\n",
       "TCGA-CV-5444-01A 0.5265173593 1.093472e-01 7.530197e-07 1.981863e-06\n",
       "TCGA-BA-5556-01A 0.0435331604 1.207894e-01 2.814119e-04 4.800570e-06\n",
       "TCGA-P3-A6SX-01A 0.1287847942 8.543231e-07 6.660487e-05 9.999336e-04\n",
       "TCGA-CV-7242-11A 0.0167292415 2.252533e-02 2.778300e-04 2.247169e-03\n",
       "TCGA-DQ-7592-01A 0.1480833868 1.267932e-02 1.418083e-04 1.125114e-03\n",
       "TCGA-CV-6937-01A 0.1790558892 6.051790e-02 8.751306e-05 2.242220e-05\n",
       "TCGA-QK-A8ZB-01A 0.1401419183 8.707466e-03 5.001437e-04 7.590702e-03\n",
       "TCGA-CV-7432-01A 0.0278294623 3.079319e-03 1.938185e-04 1.774354e-03\n",
       "TCGA-CV-7089-01A 0.0174213920 1.222554e-02 7.491191e-04 1.776548e-03\n",
       "TCGA-CV-6939-11A 0.0396254273 2.021104e-07 1.071993e-07 1.505424e-07\n",
       "TCGA-BA-4075-01A 0.0459568350 3.187023e-02 4.420085e-05 9.539326e-03\n",
       "TCGA-T3-A92M-01A 0.3363094290 7.850835e-02 2.093600e-04 3.436222e-03\n",
       "⋮                ⋮            ⋮            ⋮            ⋮           \n",
       "TCGA-CV-7430-01A 0.021582735  5.593641e-04 1.467724e-04 2.426159e-03\n",
       "TCGA-D6-A74Q-01A 0.112548057  3.924812e-03 3.830402e-03 1.229835e-02\n",
       "TCGA-CV-7255-01A 0.029518875  7.154988e-07 2.181712e-05 1.436786e-03\n",
       "TCGA-CQ-6223-01A 0.018397980  1.391535e-02 8.635799e-04 2.450946e-03\n",
       "TCGA-CV-A460-01A 0.164898903  6.736238e-02 6.974457e-04 7.328822e-03\n",
       "TCGA-CV-7261-01A 0.222022093  2.907047e-02 4.046752e-04 6.647187e-03\n",
       "TCGA-CN-4736-01A 0.203851719  1.121733e-01 2.797655e-07 2.977295e-06\n",
       "TCGA-CR-7404-01A 0.050124414  6.723222e-02 7.647812e-04 5.958792e-03\n",
       "TCGA-UF-A719-01A 0.024351152  3.394154e-03 3.964999e-05 4.026614e-03\n",
       "TCGA-CV-7236-01A 0.196991255  2.256574e-02 1.077066e-04 1.087603e-02\n",
       "TCGA-CV-6951-01A 0.080220851  1.689773e-03 6.550422e-04 1.306809e-04\n",
       "TCGA-CN-4728-01A 0.580468135  1.493368e-01 4.704836e-04 1.817814e-05\n",
       "TCGA-CV-7090-01A 0.249057663  6.615897e-02 2.877527e-04 4.511355e-03\n",
       "TCGA-CV-5979-01A 0.055552577  8.153458e-03 2.030841e-05 1.265226e-05\n",
       "TCGA-CQ-7069-01A 0.092959285  4.438142e-04 2.885009e-04 1.551036e-03\n",
       "TCGA-CN-4733-01A 0.285705707  1.685431e-01 1.672578e-03 3.460009e-03\n",
       "TCGA-CR-7390-01A 0.213920663  5.872467e-03 1.662505e-04 4.445526e-03\n",
       "TCGA-CV-A45X-01A 0.020004646  5.965875e-03 6.785496e-05 2.811138e-03\n",
       "TCGA-IQ-A6SH-01A 0.036440188  2.994372e-02 3.226413e-04 2.186796e-04\n",
       "TCGA-CV-6962-11A 0.037895283  4.559363e-03 4.198810e-04 1.897996e-03\n",
       "TCGA-CV-6960-11A 0.011001313  1.009368e-02 8.802926e-04 1.108602e-03\n",
       "TCGA-CV-A464-01A 0.365218102  1.037947e-02 8.347710e-05 6.623413e-06\n",
       "TCGA-C9-A47Z-01A 0.012865199  2.924776e-03 2.586389e-05 1.184250e-03\n",
       "TCGA-CN-6010-01A 0.092435372  1.028982e-01 8.159275e-04 7.523645e-06\n",
       "TCGA-WA-A7GZ-11A 0.011840187  2.209323e-07 1.398135e-07 1.826388e-07\n",
       "TCGA-CV-7235-01A 0.331035588  4.341405e-02 3.739575e-04 1.721061e-03\n",
       "TCGA-CX-7086-01A 0.013663174  5.613298e-03 6.030335e-05 2.351940e-03\n",
       "TCGA-CV-6935-11A 0.009082117  3.730673e-02 4.052511e-04 5.923958e-04\n",
       "TCGA-P3-A6SW-01A 0.087745865  4.834572e-02 2.908469e-03 9.189827e-06\n",
       "TCGA-HD-A6HZ-01A 0.117164007  5.056453e-02 3.987480e-04 6.222276e-03\n",
       "                 pDC-cells    Tconv-cell   Treg-cells   tumor     \n",
       "TCGA-BB-4224-01A 1.032630e-03 6.065475e-03 3.046525e-04 0.92733662\n",
       "TCGA-H7-7774-01A 1.077549e-03 5.746715e-07 7.144899e-04 0.96023355\n",
       "TCGA-CV-6943-01A 2.718970e-03 2.688987e-07 1.883073e-03 0.42282326\n",
       "TCGA-CN-5374-01A 6.411098e-03 1.306061e-02 2.010434e-02 0.83038369\n",
       "TCGA-CQ-6227-01A 1.886387e-06 1.263138e-01 8.880127e-07 0.54102366\n",
       "TCGA-CV-6959-01A 1.351226e-05 1.119808e-01 5.516346e-06 0.69115943\n",
       "TCGA-F7-A61V-01A 1.550082e-03 5.635728e-02 2.310520e-03 0.89525067\n",
       "TCGA-CV-7413-01A 3.144350e-06 2.712702e-07 8.944177e-04 0.70027072\n",
       "TCGA-CV-7247-01A 3.395621e-07 1.370786e-01 4.846298e-07 0.66569777\n",
       "TCGA-CR-5249-01A 1.360507e-02 4.213912e-07 1.656411e-02 0.76454367\n",
       "TCGA-CQ-5331-01A 3.096985e-03 2.118289e-07 1.747090e-03 0.78235360\n",
       "TCGA-BB-8601-01A 3.643543e-06 1.299555e-06 8.569433e-06 0.97476402\n",
       "TCGA-CV-A45W-01A 6.153426e-03 7.634465e-07 8.800786e-03 0.64501228\n",
       "TCGA-CQ-7063-01A 2.668512e-03 6.395263e-07 9.372649e-04 0.82795833\n",
       "TCGA-CN-5373-01A 1.702080e-03 4.758960e-04 4.261388e-06 0.68797000\n",
       "TCGA-CV-A45T-01A 2.609326e-03 3.141035e-02 8.359557e-03 0.71773096\n",
       "TCGA-HD-A4C1-01A 7.022697e-04 4.463907e-07 2.087295e-05 0.84885450\n",
       "TCGA-CV-7438-11A 4.535285e-03 8.169412e-03 1.629515e-03 0.92346829\n",
       "TCGA-CV-5444-01A 5.822362e-04 4.695905e-02 1.555470e-05 0.27918413\n",
       "TCGA-BA-5556-01A 3.438276e-03 2.952937e-07 5.626280e-03 0.75529120\n",
       "TCGA-P3-A6SX-01A 1.528918e-06 1.748934e-02 5.326699e-06 0.83130458\n",
       "TCGA-CV-7242-11A 4.396532e-03 2.856326e-05 1.092367e-03 0.92033599\n",
       "TCGA-DQ-7592-01A 8.122057e-04 2.153864e-02 3.126022e-03 0.77657213\n",
       "TCGA-CV-6937-01A 2.877875e-03 6.920554e-07 1.605688e-03 0.73210512\n",
       "TCGA-QK-A8ZB-01A 1.466250e-03 4.915362e-07 5.090307e-04 0.79596447\n",
       "TCGA-CV-7432-01A 3.044177e-04 5.025951e-07 9.925769e-04 0.94571467\n",
       "TCGA-CV-7089-01A 8.436417e-04 4.626392e-07 1.076935e-03 0.91499981\n",
       "TCGA-CV-6939-11A 1.602020e-07 8.779284e-01 1.391324e-07 0.06391068\n",
       "TCGA-BA-4075-01A 2.148848e-05 4.980788e-03 1.378718e-03 0.87501961\n",
       "TCGA-T3-A92M-01A 7.437517e-04 4.086668e-07 6.457165e-03 0.54021403\n",
       "⋮                ⋮            ⋮            ⋮            ⋮         \n",
       "TCGA-CV-7430-01A 2.901787e-05 7.895697e-07 6.417269e-06 0.9522944 \n",
       "TCGA-D6-A74Q-01A 5.718750e-03 8.259003e-07 8.751835e-03 0.8145015 \n",
       "TCGA-CV-7255-01A 4.695111e-07 1.604425e-02 5.681043e-04 0.9085115 \n",
       "TCGA-CQ-6223-01A 1.685840e-03 3.876277e-07 8.657860e-04 0.9457482 \n",
       "TCGA-CV-A460-01A 6.324749e-03 6.629139e-07 6.425260e-03 0.6303024 \n",
       "TCGA-CV-7261-01A 2.081536e-04 1.024530e-06 7.358057e-06 0.6848085 \n",
       "TCGA-CN-4736-01A 3.094837e-04 1.835070e-01 2.201801e-03 0.4435007 \n",
       "TCGA-CR-7404-01A 9.602612e-03 6.147691e-07 4.956443e-03 0.7707652 \n",
       "TCGA-UF-A719-01A 9.811350e-04 9.032943e-05 2.117762e-03 0.9247836 \n",
       "TCGA-CV-7236-01A 5.148918e-04 5.414749e-07 1.457108e-03 0.6923188 \n",
       "TCGA-CV-6951-01A 7.414515e-05 4.729976e-02 3.337689e-06 0.8573459 \n",
       "TCGA-CN-4728-01A 1.053649e-03 8.110333e-03 8.723386e-06 0.2144844 \n",
       "TCGA-CV-7090-01A 7.086549e-05 2.993599e-07 9.706727e-05 0.6009539 \n",
       "TCGA-CV-5979-01A 1.451474e-06 1.539655e-03 6.528483e-06 0.8908949 \n",
       "TCGA-CQ-7069-01A 1.919992e-05 4.770939e-07 3.649764e-06 0.8278284 \n",
       "TCGA-CN-4733-01A 2.323855e-02 1.686708e-02 8.573240e-03 0.3456848 \n",
       "TCGA-CR-7390-01A 1.206895e-06 4.301343e-07 2.897329e-06 0.7451947 \n",
       "TCGA-CV-A45X-01A 7.777258e-04 1.110329e-06 2.337816e-03 0.9493245 \n",
       "TCGA-IQ-A6SH-01A 6.891492e-04 6.732549e-07 4.617974e-04 0.8961116 \n",
       "TCGA-CV-6962-11A 2.243572e-03 1.048223e-04 8.891491e-04 0.9204774 \n",
       "TCGA-CV-6960-11A 1.712646e-03 9.216748e-05 1.391011e-05 0.9469077 \n",
       "TCGA-CV-A464-01A 2.516128e-03 7.221133e-02 5.425213e-04 0.4956189 \n",
       "TCGA-C9-A47Z-01A 1.264258e-04 6.463346e-03 1.646568e-04 0.9618175 \n",
       "TCGA-CN-6010-01A 1.319148e-06 1.907857e-02 4.058772e-06 0.7090638 \n",
       "TCGA-WA-A7GZ-11A 2.031713e-07 7.626023e-01 1.732265e-07 0.2250252 \n",
       "TCGA-CV-7235-01A 7.400603e-04 2.944636e-07 1.210964e-03 0.5571721 \n",
       "TCGA-CX-7086-01A 2.253336e-03 1.266288e-06 1.168945e-05 0.9359061 \n",
       "TCGA-CV-6935-11A 2.227567e-05 6.677475e-04 2.754238e-04 0.9228189 \n",
       "TCGA-P3-A6SW-01A 1.350914e-02 7.265310e-07 1.708835e-02 0.7411353 \n",
       "TCGA-HD-A6HZ-01A 2.939265e-03 6.468833e-02 7.463512e-03 0.6657255 "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "BP_res"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 48,
   "id": "79b4d03a",
   "metadata": {},
   "outputs": [],
   "source": [
    "write.csv(BP_res, \"/home/cke/Real/TCGAResults/BayesPrism/celltypefrac_BP_ImmuneSubtypes_real_top100DEGs_Aug8.csv\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "id": "abb951ce",
   "metadata": {},
   "outputs": [],
   "source": []
  },
  {
   "cell_type": "code",
   "execution_count": 5,
   "id": "3bcae3c9",
   "metadata": {
    "collapsed": true
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<table class=\"dataframe\">\n",
       "<caption>A matrix: 546 × 760 of type dbl</caption>\n",
       "<thead>\n",
       "\t<tr><th></th><th scope=col>ENSG00000170476</th><th scope=col>ENSG00000099958</th><th scope=col>ENSG00000134285</th><th scope=col>ENSG00000051108</th><th scope=col>ENSG00000166562</th><th scope=col>ENSG00000183508</th><th scope=col>ENSG00000254709</th><th scope=col>ENSG00000173486</th><th scope=col>ENSG00000213140</th><th scope=col>ENSG00000100219</th><th scope=col>⋯</th><th scope=col>ENSG00000197747</th><th scope=col>ENSG00000182004</th><th scope=col>ENSG00000166145</th><th scope=col>ENSG00000121552</th><th scope=col>ENSG00000139324</th><th scope=col>ENSG00000139343</th><th scope=col>ENSG00000237945</th><th scope=col>ENSG00000264230</th><th scope=col>ENSG00000185479</th><th scope=col>ENSG00000196262</th></tr>\n",
       "</thead>\n",
       "<tbody>\n",
       "\t<tr><th scope=row>TCGA.BB.4224.01A</th><td>2.049247e-06</td><td>8.278036e-06</td><td>7.993074e-05</td><td>0.0003016311</td><td>1.789655e-04</td><td>7.214426e-06</td><td>3.616179e-06</td><td>0.0003700216</td><td>1.628714e-07</td><td>1e-08</td><td>⋯</td><td>0.002737765</td><td>5.773484e-04</td><td>0.0017739162</td><td>0.0089543412</td><td>0.0008018141</td><td>6.692068e-04</td><td>2.308098e-04</td><td>4.367240e-04</td><td>0.009079472</td><td>0.013460871</td></tr>\n",
       "\t<tr><th scope=row>TCGA.H7.7774.01A</th><td>1.456508e-05</td><td>1.659493e-05</td><td>3.901972e-05</td><td>0.0003040131</td><td>1.257976e-04</td><td>2.986419e-05</td><td>9.902832e-05</td><td>0.0002230157</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.003337577</td><td>1.433087e-04</td><td>0.0014243026</td><td>0.0166559084</td><td>0.0005140027</td><td>3.059268e-04</td><td>5.841788e-05</td><td>3.626587e-04</td><td>0.084561644</td><td>0.002045631</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6943.01A</th><td>7.706264e-05</td><td>2.317288e-05</td><td>1.919155e-04</td><td>0.0003806151</td><td>1.568517e-04</td><td>9.695148e-05</td><td>4.693725e-04</td><td>0.0002469867</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.003357789</td><td>1.559257e-04</td><td>0.0038717172</td><td>0.0024351945</td><td>0.0004150751</td><td>1.871413e-04</td><td>1.157592e-04</td><td>5.567893e-04</td><td>0.054130245</td><td>0.001652089</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.5374.01A</th><td>2.662188e-05</td><td>2.049187e-05</td><td>2.066638e-04</td><td>0.0005088117</td><td>2.908512e-04</td><td>1.100708e-04</td><td>3.181145e-04</td><td>0.0005197946</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.010330342</td><td>4.239480e-04</td><td>0.0050937505</td><td>0.0026178135</td><td>0.0003574237</td><td>5.400711e-04</td><td>2.654795e-05</td><td>3.842901e-04</td><td>0.002485788</td><td>0.002593591</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.6227.01A</th><td>2.593107e-05</td><td>1.036527e-06</td><td>1.790201e-04</td><td>0.0004976070</td><td>2.497173e-04</td><td>2.936631e-05</td><td>1.234068e-05</td><td>0.0005737245</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.004530666</td><td>2.386463e-04</td><td>0.0017714377</td><td>0.0053466289</td><td>0.0005887246</td><td>2.386188e-04</td><td>1.066649e-04</td><td>4.524921e-04</td><td>0.030182147</td><td>0.002398836</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6959.01A</th><td>6.961463e-05</td><td>2.727789e-06</td><td>1.352284e-04</td><td>0.0004187407</td><td>1.303890e-04</td><td>1.003146e-04</td><td>1.818100e-04</td><td>0.0002814092</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.004082648</td><td>2.200997e-04</td><td>0.0013295819</td><td>0.0023046395</td><td>0.0004808925</td><td>3.583344e-04</td><td>7.808572e-05</td><td>3.079049e-04</td><td>0.029175120</td><td>0.002409821</td></tr>\n",
       "\t<tr><th scope=row>TCGA.F7.A61V.01A</th><td>2.830645e-05</td><td>7.561233e-06</td><td>1.369668e-04</td><td>0.0005038926</td><td>2.715256e-04</td><td>6.540110e-05</td><td>8.356970e-05</td><td>0.0006785771</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.005626857</td><td>4.308986e-04</td><td>0.0022317165</td><td>0.0323772297</td><td>0.0004708252</td><td>5.992306e-04</td><td>1.352416e-05</td><td>2.127113e-04</td><td>0.032960660</td><td>0.004283686</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7413.01A</th><td>1.785685e-05</td><td>5.282712e-06</td><td>1.218923e-04</td><td>0.0003108130</td><td>1.169820e-04</td><td>1.764722e-05</td><td>2.682257e-05</td><td>0.0003967018</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.004879131</td><td>2.800998e-04</td><td>0.0037563555</td><td>0.0017821653</td><td>0.0005171505</td><td>3.428029e-04</td><td>1.394460e-04</td><td>3.722275e-04</td><td>0.038769554</td><td>0.002416373</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7247.01A</th><td>3.811184e-06</td><td>4.289529e-07</td><td>1.450429e-04</td><td>0.0003171369</td><td>8.909711e-05</td><td>2.454457e-05</td><td>2.104127e-06</td><td>0.0002724595</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.005585513</td><td>3.754058e-04</td><td>0.0020373186</td><td>0.0029178676</td><td>0.0009947036</td><td>4.143002e-04</td><td>1.677187e-04</td><td>5.068920e-04</td><td>0.021828081</td><td>0.004925209</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CR.5249.01A</th><td>4.528438e-05</td><td>1.810596e-05</td><td>2.477341e-04</td><td>0.0007866894</td><td>2.952037e-04</td><td>3.301050e-04</td><td>3.166782e-04</td><td>0.0002964787</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.002960998</td><td>1.687711e-04</td><td>0.0031681877</td><td>0.0034204397</td><td>0.0010516075</td><td>1.980024e-04</td><td>1.816146e-04</td><td>5.952634e-04</td><td>0.011545750</td><td>0.002209561</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.5331.01A</th><td>9.156581e-05</td><td>2.989494e-05</td><td>2.648125e-04</td><td>0.0004223396</td><td>1.583459e-04</td><td>1.046004e-04</td><td>1.017654e-04</td><td>0.0002813868</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.002116966</td><td>2.158482e-04</td><td>0.0008185703</td><td>0.0104473836</td><td>0.0004349681</td><td>2.344521e-04</td><td>6.835260e-05</td><td>2.280540e-04</td><td>0.073982929</td><td>0.002414117</td></tr>\n",
       "\t<tr><th scope=row>TCGA.BB.8601.01A</th><td>1.051602e-04</td><td>6.888089e-05</td><td>1.366950e-04</td><td>0.0004107444</td><td>2.341090e-04</td><td>4.878925e-05</td><td>4.327599e-04</td><td>0.0004442685</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.005941892</td><td>7.148520e-04</td><td>0.0013883150</td><td>0.0072199093</td><td>0.0012015445</td><td>7.152516e-04</td><td>4.785123e-05</td><td>2.400354e-04</td><td>0.018089630</td><td>0.006423278</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A45W.01A</th><td>4.032253e-05</td><td>1.702758e-05</td><td>7.340113e-04</td><td>0.0019683746</td><td>5.485908e-04</td><td>3.918964e-04</td><td>6.717086e-04</td><td>0.0008967767</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.001917906</td><td>3.920446e-04</td><td>0.0019031008</td><td>0.0051938047</td><td>0.0007790055</td><td>5.906361e-04</td><td>8.620462e-05</td><td>6.646666e-05</td><td>0.002525816</td><td>0.003339710</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.7063.01A</th><td>1.235255e-05</td><td>9.993016e-06</td><td>1.319633e-04</td><td>0.0002852475</td><td>8.989533e-05</td><td>6.044874e-05</td><td>6.918289e-06</td><td>0.0002003570</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.003398543</td><td>1.586570e-04</td><td>0.0017012382</td><td>0.0032522460</td><td>0.0003016946</td><td>1.823135e-04</td><td>8.863041e-05</td><td>4.228896e-04</td><td>0.047377067</td><td>0.002186628</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.5373.01A</th><td>1.715681e-05</td><td>7.226266e-06</td><td>6.552594e-05</td><td>0.0002729102</td><td>7.044489e-05</td><td>4.893205e-05</td><td>3.333021e-05</td><td>0.0002322776</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.001655155</td><td>8.016141e-05</td><td>0.0016525510</td><td>0.0055143119</td><td>0.0005213437</td><td>9.728658e-05</td><td>8.536740e-05</td><td>4.841650e-04</td><td>0.110119547</td><td>0.001424400</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A45T.01A</th><td>6.744023e-05</td><td>2.018933e-05</td><td>2.490121e-04</td><td>0.0007053947</td><td>2.222814e-04</td><td>1.527868e-04</td><td>3.268788e-04</td><td>0.0004819631</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.004611893</td><td>3.322539e-04</td><td>0.0011057098</td><td>0.0113060985</td><td>0.0002201174</td><td>3.553431e-04</td><td>5.015535e-05</td><td>4.797819e-04</td><td>0.073378459</td><td>0.003104214</td></tr>\n",
       "\t<tr><th scope=row>TCGA.HD.A4C1.01A</th><td>1.099770e-04</td><td>1.750373e-05</td><td>2.098977e-04</td><td>0.0002674171</td><td>2.119277e-04</td><td>6.504464e-05</td><td>1.552979e-04</td><td>0.0002556994</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.004476140</td><td>2.377950e-04</td><td>0.0017209266</td><td>0.0049206500</td><td>0.0007088569</td><td>2.931246e-04</td><td>7.256049e-05</td><td>3.215368e-04</td><td>0.041926520</td><td>0.002846415</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7438.11A</th><td>5.050969e-05</td><td>1.716479e-05</td><td>1.153985e-04</td><td>0.0005002833</td><td>2.024119e-04</td><td>9.751444e-05</td><td>3.473233e-04</td><td>0.0002890306</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.004479447</td><td>2.357138e-04</td><td>0.0018305646</td><td>0.0154356225</td><td>0.0002963051</td><td>3.234816e-04</td><td>7.462886e-05</td><td>4.099938e-04</td><td>0.036995445</td><td>0.002871761</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.5444.01A</th><td>1.340258e-05</td><td>4.642889e-06</td><td>1.849706e-04</td><td>0.0003104101</td><td>1.044504e-04</td><td>2.606660e-05</td><td>2.521237e-05</td><td>0.0004050447</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.003810114</td><td>2.579929e-04</td><td>0.0026027185</td><td>0.0020095220</td><td>0.0004906207</td><td>3.024435e-04</td><td>1.801730e-04</td><td>7.470174e-04</td><td>0.020614277</td><td>0.002462434</td></tr>\n",
       "\t<tr><th scope=row>TCGA.BA.5556.01A</th><td>6.395396e-05</td><td>2.613957e-05</td><td>1.610629e-04</td><td>0.0003802627</td><td>1.302612e-04</td><td>1.518540e-04</td><td>2.494859e-04</td><td>0.0002640489</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.003600573</td><td>1.634347e-04</td><td>0.0018362387</td><td>0.0028587916</td><td>0.0003777037</td><td>2.260585e-04</td><td>1.605390e-04</td><td>4.405382e-04</td><td>0.032918689</td><td>0.002362555</td></tr>\n",
       "\t<tr><th scope=row>TCGA.P3.A6SX.01A</th><td>1.625000e-05</td><td>7.765744e-06</td><td>1.025321e-04</td><td>0.0003100384</td><td>2.586142e-04</td><td>1.561991e-05</td><td>4.604509e-06</td><td>0.0008899720</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.006280771</td><td>5.346874e-04</td><td>0.0023197761</td><td>0.0022712824</td><td>0.0005605644</td><td>5.489885e-04</td><td>6.276184e-05</td><td>1.764815e-04</td><td>0.036640466</td><td>0.004356166</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7242.11A</th><td>1.961195e-05</td><td>8.839838e-06</td><td>1.255808e-04</td><td>0.0004825937</td><td>2.408144e-04</td><td>5.441852e-05</td><td>4.136964e-05</td><td>0.0003709810</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.007369572</td><td>3.025168e-04</td><td>0.0032612093</td><td>0.0200354832</td><td>0.0002793075</td><td>4.638789e-04</td><td>5.193720e-05</td><td>2.945520e-04</td><td>0.002345791</td><td>0.003399956</td></tr>\n",
       "\t<tr><th scope=row>TCGA.DQ.7592.01A</th><td>1.305065e-05</td><td>6.278095e-06</td><td>1.836021e-04</td><td>0.0007367294</td><td>1.138705e-04</td><td>1.768199e-05</td><td>2.142013e-05</td><td>0.0002584084</td><td>5.705522e-08</td><td>1e-08</td><td>⋯</td><td>0.003336019</td><td>2.514070e-04</td><td>0.0032934795</td><td>0.0018629622</td><td>0.0005402061</td><td>2.796855e-04</td><td>8.865398e-05</td><td>3.579947e-04</td><td>0.009928997</td><td>0.003024097</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6937.01A</th><td>7.414205e-06</td><td>3.730424e-06</td><td>1.301218e-04</td><td>0.0003976488</td><td>2.396035e-04</td><td>4.740898e-04</td><td>8.759695e-06</td><td>0.0003191809</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.004346442</td><td>5.132510e-04</td><td>0.0023996582</td><td>0.0009491521</td><td>0.0003516651</td><td>3.318331e-04</td><td>6.027308e-05</td><td>6.927646e-04</td><td>0.004763760</td><td>0.003762372</td></tr>\n",
       "\t<tr><th scope=row>TCGA.QK.A8ZB.01A</th><td>7.380388e-05</td><td>4.081921e-05</td><td>3.902980e-04</td><td>0.0011514768</td><td>3.315389e-04</td><td>2.744386e-04</td><td>6.930245e-04</td><td>0.0005834410</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.002897496</td><td>2.532544e-04</td><td>0.0017825461</td><td>0.0130022214</td><td>0.0004766300</td><td>3.081891e-04</td><td>1.585205e-04</td><td>7.080066e-04</td><td>0.034975994</td><td>0.002742837</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7432.01A</th><td>1.995097e-06</td><td>9.091119e-06</td><td>1.621309e-04</td><td>0.0002019652</td><td>1.766631e-04</td><td>1.472208e-05</td><td>1.400034e-06</td><td>0.0005102209</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.006701766</td><td>3.634160e-04</td><td>0.0007841787</td><td>0.0012932573</td><td>0.0005436148</td><td>3.844492e-04</td><td>8.900618e-05</td><td>5.164222e-04</td><td>0.020327529</td><td>0.004136221</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7089.01A</th><td>1.205463e-05</td><td>8.519127e-06</td><td>8.186953e-05</td><td>0.0002950473</td><td>9.073284e-05</td><td>2.605794e-05</td><td>2.554719e-05</td><td>0.0002767261</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.007622057</td><td>2.258614e-04</td><td>0.0018506403</td><td>0.0101614970</td><td>0.0003772263</td><td>3.286588e-04</td><td>6.041428e-05</td><td>4.450423e-04</td><td>0.028509745</td><td>0.002970316</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6939.11A</th><td>1.000000e-08</td><td>1.000000e-08</td><td>6.882360e-04</td><td>0.0024088011</td><td>1.376462e-03</td><td>1.000000e-08</td><td>1.000000e-08</td><td>0.0003441230</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.000344123</td><td>1.032349e-03</td><td>0.0223673555</td><td>0.0048175921</td><td>0.0003441230</td><td>3.441230e-04</td><td>1.000000e-08</td><td>1.000000e-08</td><td>0.000344123</td><td>0.000344123</td></tr>\n",
       "\t<tr><th scope=row>TCGA.BA.4075.01A</th><td>9.427073e-07</td><td>4.890226e-06</td><td>2.629682e-04</td><td>0.0005298174</td><td>1.574309e-04</td><td>5.007992e-06</td><td>4.625084e-06</td><td>0.0002565718</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.008498127</td><td>6.507726e-04</td><td>0.0008981257</td><td>0.0017960672</td><td>0.0002748242</td><td>3.098169e-04</td><td>9.336014e-05</td><td>5.669379e-04</td><td>0.004266577</td><td>0.012449356</td></tr>\n",
       "\t<tr><th scope=row>TCGA.T3.A92M.01A</th><td>9.909917e-05</td><td>3.355913e-05</td><td>3.052128e-04</td><td>0.0008003329</td><td>3.846975e-04</td><td>1.233704e-04</td><td>4.426472e-04</td><td>0.0004964614</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.004055301</td><td>6.537091e-04</td><td>0.0017117580</td><td>0.0015475192</td><td>0.0006276969</td><td>1.026578e-03</td><td>9.259499e-05</td><td>3.069821e-04</td><td>0.007744020</td><td>0.003446403</td></tr>\n",
       "\t<tr><th scope=row>⋮</th><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋱</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7430.01A</th><td>8.104140e-06</td><td>5.776797e-06</td><td>6.750206e-05</td><td>0.0002853851</td><td>9.439273e-05</td><td>1.941104e-05</td><td>2.524718e-05</td><td>0.0002446748</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.007121540</td><td>0.0002895846</td><td>0.0036654498</td><td>0.0048225068</td><td>0.0006275938</td><td>0.0003736934</td><td>4.550609e-05</td><td>0.0005383872</td><td>0.0145368126</td><td>0.001343983</td></tr>\n",
       "\t<tr><th scope=row>TCGA.D6.A74Q.01A</th><td>5.337087e-05</td><td>2.874010e-05</td><td>3.116200e-04</td><td>0.0007130012</td><td>1.958654e-04</td><td>1.671915e-04</td><td>5.210625e-04</td><td>0.0006809090</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.005756178</td><td>0.0006227999</td><td>0.0019739963</td><td>0.0054332114</td><td>0.0006227270</td><td>0.0007671214</td><td>7.493450e-05</td><td>0.0004953226</td><td>0.0095378436</td><td>0.005052232</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7255.01A</th><td>5.878292e-06</td><td>1.421801e-06</td><td>4.910690e-05</td><td>0.0002940495</td><td>1.313624e-04</td><td>1.057609e-05</td><td>2.235211e-05</td><td>0.0005886989</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.005428264</td><td>0.0002686081</td><td>0.0025571581</td><td>0.0021710324</td><td>0.0003400059</td><td>0.0001293436</td><td>1.606496e-04</td><td>0.0006389083</td><td>0.0108127902</td><td>0.003692008</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.6223.01A</th><td>4.435995e-05</td><td>4.009854e-05</td><td>6.211937e-05</td><td>0.0004650225</td><td>7.399283e-05</td><td>7.493441e-05</td><td>1.756797e-04</td><td>0.0002270226</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.003053088</td><td>0.0001634606</td><td>0.0022289593</td><td>0.0077123084</td><td>0.0004166915</td><td>0.0002387974</td><td>4.522391e-05</td><td>0.0002499937</td><td>0.0602492184</td><td>0.002551418</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A460.01A</th><td>5.011232e-05</td><td>3.603755e-05</td><td>2.293757e-04</td><td>0.0009944662</td><td>3.764719e-04</td><td>1.673545e-04</td><td>4.979068e-04</td><td>0.0005998793</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.003110662</td><td>0.0004130311</td><td>0.0023860029</td><td>0.0026728659</td><td>0.0006409095</td><td>0.0006411616</td><td>9.773172e-05</td><td>0.0002105587</td><td>0.0038085032</td><td>0.004627804</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7261.01A</th><td>3.942927e-05</td><td>2.204710e-05</td><td>2.044807e-04</td><td>0.0011940780</td><td>1.745750e-04</td><td>7.122713e-05</td><td>4.453275e-04</td><td>0.0002607408</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.003258928</td><td>0.0004946441</td><td>0.0011090316</td><td>0.0016310078</td><td>0.0012178321</td><td>0.0004925674</td><td>6.676863e-05</td><td>0.0001493141</td><td>0.0172405230</td><td>0.002004587</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.4736.01A</th><td>1.390749e-05</td><td>8.769088e-07</td><td>1.223342e-04</td><td>0.0003837442</td><td>2.142997e-04</td><td>6.283548e-05</td><td>1.596004e-05</td><td>0.0004530299</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.002296859</td><td>0.0001688855</td><td>0.0031227601</td><td>0.0023390499</td><td>0.0008105389</td><td>0.0001891924</td><td>1.701151e-04</td><td>0.0009726216</td><td>0.0386288860</td><td>0.001846247</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CR.7404.01A</th><td>6.644734e-05</td><td>2.869323e-05</td><td>2.431157e-04</td><td>0.0006640946</td><td>3.876657e-04</td><td>3.220030e-04</td><td>4.117645e-04</td><td>0.0004241875</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.003802623</td><td>0.0003162880</td><td>0.0035471866</td><td>0.0058780413</td><td>0.0008346040</td><td>0.0004172660</td><td>3.501289e-04</td><td>0.0001747886</td><td>0.0043973878</td><td>0.002804166</td></tr>\n",
       "\t<tr><th scope=row>TCGA.UF.A719.01A</th><td>5.100094e-05</td><td>4.090135e-05</td><td>8.886602e-05</td><td>0.0005454100</td><td>2.660999e-04</td><td>3.933922e-05</td><td>1.057499e-04</td><td>0.0006982935</td><td>1.265862e-07</td><td>1e-08</td><td>⋯</td><td>0.003819092</td><td>0.0005531189</td><td>0.0034956357</td><td>0.0108619360</td><td>0.0004804429</td><td>0.0004463037</td><td>1.825883e-04</td><td>0.0002105398</td><td>0.0061043322</td><td>0.002410001</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7236.01A</th><td>3.252200e-05</td><td>5.488452e-06</td><td>1.092472e-04</td><td>0.0003468501</td><td>1.309125e-04</td><td>5.986113e-05</td><td>3.696085e-05</td><td>0.0002600968</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.006065872</td><td>0.0002268857</td><td>0.0027198014</td><td>0.0005824110</td><td>0.0008134314</td><td>0.0002646659</td><td>1.159172e-04</td><td>0.0008765738</td><td>0.0277032892</td><td>0.003632712</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6951.01A</th><td>1.005896e-05</td><td>6.093762e-06</td><td>1.052292e-04</td><td>0.0003327380</td><td>2.115928e-04</td><td>2.419086e-05</td><td>1.306260e-05</td><td>0.0005985506</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.003143431</td><td>0.0003646987</td><td>0.0025639218</td><td>0.0020115784</td><td>0.0012760151</td><td>0.0003109368</td><td>9.188377e-05</td><td>0.0002664351</td><td>0.0191011166</td><td>0.003565509</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.4728.01A</th><td>2.228636e-05</td><td>1.355492e-05</td><td>1.684279e-04</td><td>0.0005285901</td><td>2.218801e-04</td><td>3.632771e-05</td><td>8.188667e-05</td><td>0.0002971218</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.004889457</td><td>0.0002230085</td><td>0.0029011805</td><td>0.0052395438</td><td>0.0004271121</td><td>0.0002519848</td><td>1.238790e-04</td><td>0.0006565699</td><td>0.0325675873</td><td>0.002063437</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7090.01A</th><td>1.348566e-05</td><td>2.360787e-06</td><td>1.571082e-04</td><td>0.0003596658</td><td>1.054820e-04</td><td>2.264753e-05</td><td>9.385449e-06</td><td>0.0003380583</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.003985342</td><td>0.0001846142</td><td>0.0017219079</td><td>0.0010546015</td><td>0.0005727302</td><td>0.0002025254</td><td>5.760173e-05</td><td>0.0002389454</td><td>0.0243289623</td><td>0.002574986</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.5979.01A</th><td>1.985399e-06</td><td>1.624909e-06</td><td>9.627707e-05</td><td>0.0005035822</td><td>5.120770e-05</td><td>1.299737e-05</td><td>4.211574e-06</td><td>0.0003494897</td><td>8.458415e-08</td><td>1e-08</td><td>⋯</td><td>0.009375253</td><td>0.0002882151</td><td>0.0009895547</td><td>0.0014856896</td><td>0.0004415379</td><td>0.0002778468</td><td>3.733991e-05</td><td>0.0005769098</td><td>0.0267583905</td><td>0.002554498</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.7069.01A</th><td>1.186905e-05</td><td>6.942541e-06</td><td>7.473759e-05</td><td>0.0002819953</td><td>1.390721e-04</td><td>2.762522e-05</td><td>4.101573e-06</td><td>0.0004693662</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.005293376</td><td>0.0001213396</td><td>0.0021885387</td><td>0.0015807052</td><td>0.0005381306</td><td>0.0001384772</td><td>2.787824e-05</td><td>0.0002499133</td><td>0.0364606068</td><td>0.002397554</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.4733.01A</th><td>6.843495e-05</td><td>1.363237e-05</td><td>6.723509e-04</td><td>0.0012068362</td><td>5.583519e-04</td><td>6.333076e-04</td><td>2.022035e-04</td><td>0.0004555842</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.002585773</td><td>0.0002927561</td><td>0.0011298140</td><td>0.0013298247</td><td>0.0004118300</td><td>0.0003140261</td><td>1.196029e-04</td><td>0.0003824203</td><td>0.0179908098</td><td>0.002058683</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CR.7390.01A</th><td>1.012182e-05</td><td>2.742299e-06</td><td>9.313826e-05</td><td>0.0004419969</td><td>8.526116e-05</td><td>1.848770e-05</td><td>2.279696e-05</td><td>0.0002935566</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.003986079</td><td>0.0002778338</td><td>0.0024745965</td><td>0.0032429093</td><td>0.0004728013</td><td>0.0001709763</td><td>4.543200e-05</td><td>0.0003704545</td><td>0.0225988761</td><td>0.002880202</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A45X.01A</th><td>1.982327e-05</td><td>1.852276e-05</td><td>1.147817e-04</td><td>0.0003150305</td><td>1.603280e-04</td><td>1.857990e-05</td><td>2.948244e-05</td><td>0.0003965018</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.005119607</td><td>0.0002482347</td><td>0.0037442767</td><td>0.0094928233</td><td>0.0002827414</td><td>0.0002545380</td><td>7.346472e-05</td><td>0.0002453223</td><td>0.0181047634</td><td>0.005153022</td></tr>\n",
       "\t<tr><th scope=row>TCGA.IQ.A6SH.01A</th><td>5.290873e-05</td><td>2.686428e-05</td><td>2.361949e-04</td><td>0.0005290442</td><td>1.773073e-04</td><td>3.919241e-05</td><td>2.574518e-04</td><td>0.0010084499</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.006610426</td><td>0.0004966262</td><td>0.0017259967</td><td>0.0029736185</td><td>0.0002355422</td><td>0.0004633796</td><td>8.418996e-05</td><td>0.0003543382</td><td>0.0480659416</td><td>0.004541411</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6962.11A</th><td>2.605594e-05</td><td>1.430024e-05</td><td>7.174069e-05</td><td>0.0003952625</td><td>1.381772e-04</td><td>5.441342e-05</td><td>1.668698e-04</td><td>0.0002953859</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.006503971</td><td>0.0001457363</td><td>0.0051940113</td><td>0.0194390703</td><td>0.0002386599</td><td>0.0001966075</td><td>1.001317e-04</td><td>0.0004664489</td><td>0.0064596702</td><td>0.002182135</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6960.11A</th><td>5.507670e-06</td><td>6.364167e-06</td><td>8.184837e-05</td><td>0.0006173584</td><td>1.908321e-04</td><td>5.381925e-05</td><td>1.531101e-05</td><td>0.0002441374</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.006409453</td><td>0.0002095843</td><td>0.0028872163</td><td>0.0110644614</td><td>0.0004092271</td><td>0.0002899279</td><td>7.510687e-05</td><td>0.0002899852</td><td>0.0061605791</td><td>0.002550240</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A464.01A</th><td>1.827661e-05</td><td>2.765335e-06</td><td>1.891166e-04</td><td>0.0005600828</td><td>2.327449e-04</td><td>2.054429e-05</td><td>1.001617e-05</td><td>0.0004629118</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.004771309</td><td>0.0003365614</td><td>0.0021381656</td><td>0.0012481794</td><td>0.0006264352</td><td>0.0004487420</td><td>7.497420e-05</td><td>0.0005972093</td><td>0.0293922083</td><td>0.002852930</td></tr>\n",
       "\t<tr><th scope=row>TCGA.C9.A47Z.01A</th><td>8.938936e-06</td><td>4.649978e-06</td><td>8.093006e-05</td><td>0.0003100898</td><td>1.004789e-04</td><td>1.261151e-05</td><td>1.596038e-05</td><td>0.0002968109</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.002239680</td><td>0.0001309478</td><td>0.0015309809</td><td>0.0059378962</td><td>0.0006212079</td><td>0.0001875071</td><td>7.887333e-05</td><td>0.0005531027</td><td>0.0992483984</td><td>0.002564241</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.6010.01A</th><td>2.089121e-05</td><td>1.334562e-05</td><td>2.763071e-04</td><td>0.0012088467</td><td>2.459090e-04</td><td>2.192413e-04</td><td>2.586062e-04</td><td>0.0003568362</td><td>1.624118e-08</td><td>1e-08</td><td>⋯</td><td>0.003840012</td><td>0.0004233957</td><td>0.0021606340</td><td>0.0007145344</td><td>0.0015495287</td><td>0.0005200101</td><td>8.844130e-05</td><td>0.0002229744</td><td>0.0082722783</td><td>0.002362312</td></tr>\n",
       "\t<tr><th scope=row>TCGA.WA.A7GZ.11A</th><td>7.893354e-07</td><td>4.370099e-08</td><td>1.080259e-04</td><td>0.0005148579</td><td>2.727584e-04</td><td>3.413857e-05</td><td>1.995681e-07</td><td>0.0002593855</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.003282486</td><td>0.0002161534</td><td>0.0053297142</td><td>0.0489133412</td><td>0.0004428642</td><td>0.0002246060</td><td>4.091036e-05</td><td>0.0007222012</td><td>0.0020397140</td><td>0.001236956</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7235.01A</th><td>2.601504e-06</td><td>1.517452e-06</td><td>1.119294e-04</td><td>0.0002247817</td><td>8.398276e-05</td><td>3.821899e-05</td><td>5.479168e-06</td><td>0.0003393481</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.004799518</td><td>0.0002369377</td><td>0.0015920840</td><td>0.0001192039</td><td>0.0006553211</td><td>0.0002931653</td><td>6.543051e-05</td><td>0.0002908468</td><td>0.0007669689</td><td>0.003346472</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CX.7086.01A</th><td>4.055162e-05</td><td>2.509406e-05</td><td>9.185760e-05</td><td>0.0007694788</td><td>1.362761e-04</td><td>7.474478e-05</td><td>2.588934e-04</td><td>0.0002799019</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.002860567</td><td>0.0002871156</td><td>0.0020469296</td><td>0.0110965045</td><td>0.0004396349</td><td>0.0003355767</td><td>3.549545e-05</td><td>0.0002100881</td><td>0.0338536139</td><td>0.003258462</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6935.11A</th><td>1.386939e-05</td><td>1.191753e-05</td><td>8.580734e-05</td><td>0.0004130733</td><td>2.043172e-04</td><td>8.868809e-05</td><td>7.729184e-05</td><td>0.0002672378</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.004900983</td><td>0.0001527211</td><td>0.0033053024</td><td>0.0186461451</td><td>0.0003531671</td><td>0.0002227639</td><td>5.020764e-05</td><td>0.0002912144</td><td>0.0094543972</td><td>0.002323451</td></tr>\n",
       "\t<tr><th scope=row>TCGA.P3.A6SW.01A</th><td>6.539912e-05</td><td>2.987839e-05</td><td>7.046281e-04</td><td>0.0020177067</td><td>5.459469e-04</td><td>2.847305e-04</td><td>3.736049e-04</td><td>0.0007576098</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.005294263</td><td>0.0008564356</td><td>0.0038805225</td><td>0.0054065055</td><td>0.0005171346</td><td>0.0009597469</td><td>1.195716e-04</td><td>0.0003468781</td><td>0.0036510506</td><td>0.006277217</td></tr>\n",
       "\t<tr><th scope=row>TCGA.HD.A6HZ.01A</th><td>3.281303e-05</td><td>9.207355e-06</td><td>2.755016e-04</td><td>0.0007267136</td><td>1.949370e-04</td><td>1.929092e-04</td><td>5.411360e-04</td><td>0.0002785809</td><td>1.000000e-08</td><td>1e-08</td><td>⋯</td><td>0.006158281</td><td>0.0003242550</td><td>0.0018518827</td><td>0.0028840979</td><td>0.0009633043</td><td>0.0003997828</td><td>1.216862e-04</td><td>0.0003307637</td><td>0.0263178340</td><td>0.002522418</td></tr>\n",
       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "A matrix: 546 × 760 of type dbl\n",
       "\\begin{tabular}{r|lllllllllllllllllllll}\n",
       "  & ENSG00000170476 & ENSG00000099958 & ENSG00000134285 & ENSG00000051108 & ENSG00000166562 & ENSG00000183508 & ENSG00000254709 & ENSG00000173486 & ENSG00000213140 & ENSG00000100219 & ⋯ & ENSG00000197747 & ENSG00000182004 & ENSG00000166145 & ENSG00000121552 & ENSG00000139324 & ENSG00000139343 & ENSG00000237945 & ENSG00000264230 & ENSG00000185479 & ENSG00000196262\\\\\n",
       "\\hline\n",
       "\tTCGA.BB.4224.01A & 2.049247e-06 & 8.278036e-06 & 7.993074e-05 & 0.0003016311 & 1.789655e-04 & 7.214426e-06 & 3.616179e-06 & 0.0003700216 & 1.628714e-07 & 1e-08 & ⋯ & 0.002737765 & 5.773484e-04 & 0.0017739162 & 0.0089543412 & 0.0008018141 & 6.692068e-04 & 2.308098e-04 & 4.367240e-04 & 0.009079472 & 0.013460871\\\\\n",
       "\tTCGA.H7.7774.01A & 1.456508e-05 & 1.659493e-05 & 3.901972e-05 & 0.0003040131 & 1.257976e-04 & 2.986419e-05 & 9.902832e-05 & 0.0002230157 & 1.000000e-08 & 1e-08 & ⋯ & 0.003337577 & 1.433087e-04 & 0.0014243026 & 0.0166559084 & 0.0005140027 & 3.059268e-04 & 5.841788e-05 & 3.626587e-04 & 0.084561644 & 0.002045631\\\\\n",
       "\tTCGA.CV.6943.01A & 7.706264e-05 & 2.317288e-05 & 1.919155e-04 & 0.0003806151 & 1.568517e-04 & 9.695148e-05 & 4.693725e-04 & 0.0002469867 & 1.000000e-08 & 1e-08 & ⋯ & 0.003357789 & 1.559257e-04 & 0.0038717172 & 0.0024351945 & 0.0004150751 & 1.871413e-04 & 1.157592e-04 & 5.567893e-04 & 0.054130245 & 0.001652089\\\\\n",
       "\tTCGA.CN.5374.01A & 2.662188e-05 & 2.049187e-05 & 2.066638e-04 & 0.0005088117 & 2.908512e-04 & 1.100708e-04 & 3.181145e-04 & 0.0005197946 & 1.000000e-08 & 1e-08 & ⋯ & 0.010330342 & 4.239480e-04 & 0.0050937505 & 0.0026178135 & 0.0003574237 & 5.400711e-04 & 2.654795e-05 & 3.842901e-04 & 0.002485788 & 0.002593591\\\\\n",
       "\tTCGA.CQ.6227.01A & 2.593107e-05 & 1.036527e-06 & 1.790201e-04 & 0.0004976070 & 2.497173e-04 & 2.936631e-05 & 1.234068e-05 & 0.0005737245 & 1.000000e-08 & 1e-08 & ⋯ & 0.004530666 & 2.386463e-04 & 0.0017714377 & 0.0053466289 & 0.0005887246 & 2.386188e-04 & 1.066649e-04 & 4.524921e-04 & 0.030182147 & 0.002398836\\\\\n",
       "\tTCGA.CV.6959.01A & 6.961463e-05 & 2.727789e-06 & 1.352284e-04 & 0.0004187407 & 1.303890e-04 & 1.003146e-04 & 1.818100e-04 & 0.0002814092 & 1.000000e-08 & 1e-08 & ⋯ & 0.004082648 & 2.200997e-04 & 0.0013295819 & 0.0023046395 & 0.0004808925 & 3.583344e-04 & 7.808572e-05 & 3.079049e-04 & 0.029175120 & 0.002409821\\\\\n",
       "\tTCGA.F7.A61V.01A & 2.830645e-05 & 7.561233e-06 & 1.369668e-04 & 0.0005038926 & 2.715256e-04 & 6.540110e-05 & 8.356970e-05 & 0.0006785771 & 1.000000e-08 & 1e-08 & ⋯ & 0.005626857 & 4.308986e-04 & 0.0022317165 & 0.0323772297 & 0.0004708252 & 5.992306e-04 & 1.352416e-05 & 2.127113e-04 & 0.032960660 & 0.004283686\\\\\n",
       "\tTCGA.CV.7413.01A & 1.785685e-05 & 5.282712e-06 & 1.218923e-04 & 0.0003108130 & 1.169820e-04 & 1.764722e-05 & 2.682257e-05 & 0.0003967018 & 1.000000e-08 & 1e-08 & ⋯ & 0.004879131 & 2.800998e-04 & 0.0037563555 & 0.0017821653 & 0.0005171505 & 3.428029e-04 & 1.394460e-04 & 3.722275e-04 & 0.038769554 & 0.002416373\\\\\n",
       "\tTCGA.CV.7247.01A & 3.811184e-06 & 4.289529e-07 & 1.450429e-04 & 0.0003171369 & 8.909711e-05 & 2.454457e-05 & 2.104127e-06 & 0.0002724595 & 1.000000e-08 & 1e-08 & ⋯ & 0.005585513 & 3.754058e-04 & 0.0020373186 & 0.0029178676 & 0.0009947036 & 4.143002e-04 & 1.677187e-04 & 5.068920e-04 & 0.021828081 & 0.004925209\\\\\n",
       "\tTCGA.CR.5249.01A & 4.528438e-05 & 1.810596e-05 & 2.477341e-04 & 0.0007866894 & 2.952037e-04 & 3.301050e-04 & 3.166782e-04 & 0.0002964787 & 1.000000e-08 & 1e-08 & ⋯ & 0.002960998 & 1.687711e-04 & 0.0031681877 & 0.0034204397 & 0.0010516075 & 1.980024e-04 & 1.816146e-04 & 5.952634e-04 & 0.011545750 & 0.002209561\\\\\n",
       "\tTCGA.CQ.5331.01A & 9.156581e-05 & 2.989494e-05 & 2.648125e-04 & 0.0004223396 & 1.583459e-04 & 1.046004e-04 & 1.017654e-04 & 0.0002813868 & 1.000000e-08 & 1e-08 & ⋯ & 0.002116966 & 2.158482e-04 & 0.0008185703 & 0.0104473836 & 0.0004349681 & 2.344521e-04 & 6.835260e-05 & 2.280540e-04 & 0.073982929 & 0.002414117\\\\\n",
       "\tTCGA.BB.8601.01A & 1.051602e-04 & 6.888089e-05 & 1.366950e-04 & 0.0004107444 & 2.341090e-04 & 4.878925e-05 & 4.327599e-04 & 0.0004442685 & 1.000000e-08 & 1e-08 & ⋯ & 0.005941892 & 7.148520e-04 & 0.0013883150 & 0.0072199093 & 0.0012015445 & 7.152516e-04 & 4.785123e-05 & 2.400354e-04 & 0.018089630 & 0.006423278\\\\\n",
       "\tTCGA.CV.A45W.01A & 4.032253e-05 & 1.702758e-05 & 7.340113e-04 & 0.0019683746 & 5.485908e-04 & 3.918964e-04 & 6.717086e-04 & 0.0008967767 & 1.000000e-08 & 1e-08 & ⋯ & 0.001917906 & 3.920446e-04 & 0.0019031008 & 0.0051938047 & 0.0007790055 & 5.906361e-04 & 8.620462e-05 & 6.646666e-05 & 0.002525816 & 0.003339710\\\\\n",
       "\tTCGA.CQ.7063.01A & 1.235255e-05 & 9.993016e-06 & 1.319633e-04 & 0.0002852475 & 8.989533e-05 & 6.044874e-05 & 6.918289e-06 & 0.0002003570 & 1.000000e-08 & 1e-08 & ⋯ & 0.003398543 & 1.586570e-04 & 0.0017012382 & 0.0032522460 & 0.0003016946 & 1.823135e-04 & 8.863041e-05 & 4.228896e-04 & 0.047377067 & 0.002186628\\\\\n",
       "\tTCGA.CN.5373.01A & 1.715681e-05 & 7.226266e-06 & 6.552594e-05 & 0.0002729102 & 7.044489e-05 & 4.893205e-05 & 3.333021e-05 & 0.0002322776 & 1.000000e-08 & 1e-08 & ⋯ & 0.001655155 & 8.016141e-05 & 0.0016525510 & 0.0055143119 & 0.0005213437 & 9.728658e-05 & 8.536740e-05 & 4.841650e-04 & 0.110119547 & 0.001424400\\\\\n",
       "\tTCGA.CV.A45T.01A & 6.744023e-05 & 2.018933e-05 & 2.490121e-04 & 0.0007053947 & 2.222814e-04 & 1.527868e-04 & 3.268788e-04 & 0.0004819631 & 1.000000e-08 & 1e-08 & ⋯ & 0.004611893 & 3.322539e-04 & 0.0011057098 & 0.0113060985 & 0.0002201174 & 3.553431e-04 & 5.015535e-05 & 4.797819e-04 & 0.073378459 & 0.003104214\\\\\n",
       "\tTCGA.HD.A4C1.01A & 1.099770e-04 & 1.750373e-05 & 2.098977e-04 & 0.0002674171 & 2.119277e-04 & 6.504464e-05 & 1.552979e-04 & 0.0002556994 & 1.000000e-08 & 1e-08 & ⋯ & 0.004476140 & 2.377950e-04 & 0.0017209266 & 0.0049206500 & 0.0007088569 & 2.931246e-04 & 7.256049e-05 & 3.215368e-04 & 0.041926520 & 0.002846415\\\\\n",
       "\tTCGA.CV.7438.11A & 5.050969e-05 & 1.716479e-05 & 1.153985e-04 & 0.0005002833 & 2.024119e-04 & 9.751444e-05 & 3.473233e-04 & 0.0002890306 & 1.000000e-08 & 1e-08 & ⋯ & 0.004479447 & 2.357138e-04 & 0.0018305646 & 0.0154356225 & 0.0002963051 & 3.234816e-04 & 7.462886e-05 & 4.099938e-04 & 0.036995445 & 0.002871761\\\\\n",
       "\tTCGA.CV.5444.01A & 1.340258e-05 & 4.642889e-06 & 1.849706e-04 & 0.0003104101 & 1.044504e-04 & 2.606660e-05 & 2.521237e-05 & 0.0004050447 & 1.000000e-08 & 1e-08 & ⋯ & 0.003810114 & 2.579929e-04 & 0.0026027185 & 0.0020095220 & 0.0004906207 & 3.024435e-04 & 1.801730e-04 & 7.470174e-04 & 0.020614277 & 0.002462434\\\\\n",
       "\tTCGA.BA.5556.01A & 6.395396e-05 & 2.613957e-05 & 1.610629e-04 & 0.0003802627 & 1.302612e-04 & 1.518540e-04 & 2.494859e-04 & 0.0002640489 & 1.000000e-08 & 1e-08 & ⋯ & 0.003600573 & 1.634347e-04 & 0.0018362387 & 0.0028587916 & 0.0003777037 & 2.260585e-04 & 1.605390e-04 & 4.405382e-04 & 0.032918689 & 0.002362555\\\\\n",
       "\tTCGA.P3.A6SX.01A & 1.625000e-05 & 7.765744e-06 & 1.025321e-04 & 0.0003100384 & 2.586142e-04 & 1.561991e-05 & 4.604509e-06 & 0.0008899720 & 1.000000e-08 & 1e-08 & ⋯ & 0.006280771 & 5.346874e-04 & 0.0023197761 & 0.0022712824 & 0.0005605644 & 5.489885e-04 & 6.276184e-05 & 1.764815e-04 & 0.036640466 & 0.004356166\\\\\n",
       "\tTCGA.CV.7242.11A & 1.961195e-05 & 8.839838e-06 & 1.255808e-04 & 0.0004825937 & 2.408144e-04 & 5.441852e-05 & 4.136964e-05 & 0.0003709810 & 1.000000e-08 & 1e-08 & ⋯ & 0.007369572 & 3.025168e-04 & 0.0032612093 & 0.0200354832 & 0.0002793075 & 4.638789e-04 & 5.193720e-05 & 2.945520e-04 & 0.002345791 & 0.003399956\\\\\n",
       "\tTCGA.DQ.7592.01A & 1.305065e-05 & 6.278095e-06 & 1.836021e-04 & 0.0007367294 & 1.138705e-04 & 1.768199e-05 & 2.142013e-05 & 0.0002584084 & 5.705522e-08 & 1e-08 & ⋯ & 0.003336019 & 2.514070e-04 & 0.0032934795 & 0.0018629622 & 0.0005402061 & 2.796855e-04 & 8.865398e-05 & 3.579947e-04 & 0.009928997 & 0.003024097\\\\\n",
       "\tTCGA.CV.6937.01A & 7.414205e-06 & 3.730424e-06 & 1.301218e-04 & 0.0003976488 & 2.396035e-04 & 4.740898e-04 & 8.759695e-06 & 0.0003191809 & 1.000000e-08 & 1e-08 & ⋯ & 0.004346442 & 5.132510e-04 & 0.0023996582 & 0.0009491521 & 0.0003516651 & 3.318331e-04 & 6.027308e-05 & 6.927646e-04 & 0.004763760 & 0.003762372\\\\\n",
       "\tTCGA.QK.A8ZB.01A & 7.380388e-05 & 4.081921e-05 & 3.902980e-04 & 0.0011514768 & 3.315389e-04 & 2.744386e-04 & 6.930245e-04 & 0.0005834410 & 1.000000e-08 & 1e-08 & ⋯ & 0.002897496 & 2.532544e-04 & 0.0017825461 & 0.0130022214 & 0.0004766300 & 3.081891e-04 & 1.585205e-04 & 7.080066e-04 & 0.034975994 & 0.002742837\\\\\n",
       "\tTCGA.CV.7432.01A & 1.995097e-06 & 9.091119e-06 & 1.621309e-04 & 0.0002019652 & 1.766631e-04 & 1.472208e-05 & 1.400034e-06 & 0.0005102209 & 1.000000e-08 & 1e-08 & ⋯ & 0.006701766 & 3.634160e-04 & 0.0007841787 & 0.0012932573 & 0.0005436148 & 3.844492e-04 & 8.900618e-05 & 5.164222e-04 & 0.020327529 & 0.004136221\\\\\n",
       "\tTCGA.CV.7089.01A & 1.205463e-05 & 8.519127e-06 & 8.186953e-05 & 0.0002950473 & 9.073284e-05 & 2.605794e-05 & 2.554719e-05 & 0.0002767261 & 1.000000e-08 & 1e-08 & ⋯ & 0.007622057 & 2.258614e-04 & 0.0018506403 & 0.0101614970 & 0.0003772263 & 3.286588e-04 & 6.041428e-05 & 4.450423e-04 & 0.028509745 & 0.002970316\\\\\n",
       "\tTCGA.CV.6939.11A & 1.000000e-08 & 1.000000e-08 & 6.882360e-04 & 0.0024088011 & 1.376462e-03 & 1.000000e-08 & 1.000000e-08 & 0.0003441230 & 1.000000e-08 & 1e-08 & ⋯ & 0.000344123 & 1.032349e-03 & 0.0223673555 & 0.0048175921 & 0.0003441230 & 3.441230e-04 & 1.000000e-08 & 1.000000e-08 & 0.000344123 & 0.000344123\\\\\n",
       "\tTCGA.BA.4075.01A & 9.427073e-07 & 4.890226e-06 & 2.629682e-04 & 0.0005298174 & 1.574309e-04 & 5.007992e-06 & 4.625084e-06 & 0.0002565718 & 1.000000e-08 & 1e-08 & ⋯ & 0.008498127 & 6.507726e-04 & 0.0008981257 & 0.0017960672 & 0.0002748242 & 3.098169e-04 & 9.336014e-05 & 5.669379e-04 & 0.004266577 & 0.012449356\\\\\n",
       "\tTCGA.T3.A92M.01A & 9.909917e-05 & 3.355913e-05 & 3.052128e-04 & 0.0008003329 & 3.846975e-04 & 1.233704e-04 & 4.426472e-04 & 0.0004964614 & 1.000000e-08 & 1e-08 & ⋯ & 0.004055301 & 6.537091e-04 & 0.0017117580 & 0.0015475192 & 0.0006276969 & 1.026578e-03 & 9.259499e-05 & 3.069821e-04 & 0.007744020 & 0.003446403\\\\\n",
       "\t⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋱ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮\\\\\n",
       "\tTCGA.CV.7430.01A & 8.104140e-06 & 5.776797e-06 & 6.750206e-05 & 0.0002853851 & 9.439273e-05 & 1.941104e-05 & 2.524718e-05 & 0.0002446748 & 1.000000e-08 & 1e-08 & ⋯ & 0.007121540 & 0.0002895846 & 0.0036654498 & 0.0048225068 & 0.0006275938 & 0.0003736934 & 4.550609e-05 & 0.0005383872 & 0.0145368126 & 0.001343983\\\\\n",
       "\tTCGA.D6.A74Q.01A & 5.337087e-05 & 2.874010e-05 & 3.116200e-04 & 0.0007130012 & 1.958654e-04 & 1.671915e-04 & 5.210625e-04 & 0.0006809090 & 1.000000e-08 & 1e-08 & ⋯ & 0.005756178 & 0.0006227999 & 0.0019739963 & 0.0054332114 & 0.0006227270 & 0.0007671214 & 7.493450e-05 & 0.0004953226 & 0.0095378436 & 0.005052232\\\\\n",
       "\tTCGA.CV.7255.01A & 5.878292e-06 & 1.421801e-06 & 4.910690e-05 & 0.0002940495 & 1.313624e-04 & 1.057609e-05 & 2.235211e-05 & 0.0005886989 & 1.000000e-08 & 1e-08 & ⋯ & 0.005428264 & 0.0002686081 & 0.0025571581 & 0.0021710324 & 0.0003400059 & 0.0001293436 & 1.606496e-04 & 0.0006389083 & 0.0108127902 & 0.003692008\\\\\n",
       "\tTCGA.CQ.6223.01A & 4.435995e-05 & 4.009854e-05 & 6.211937e-05 & 0.0004650225 & 7.399283e-05 & 7.493441e-05 & 1.756797e-04 & 0.0002270226 & 1.000000e-08 & 1e-08 & ⋯ & 0.003053088 & 0.0001634606 & 0.0022289593 & 0.0077123084 & 0.0004166915 & 0.0002387974 & 4.522391e-05 & 0.0002499937 & 0.0602492184 & 0.002551418\\\\\n",
       "\tTCGA.CV.A460.01A & 5.011232e-05 & 3.603755e-05 & 2.293757e-04 & 0.0009944662 & 3.764719e-04 & 1.673545e-04 & 4.979068e-04 & 0.0005998793 & 1.000000e-08 & 1e-08 & ⋯ & 0.003110662 & 0.0004130311 & 0.0023860029 & 0.0026728659 & 0.0006409095 & 0.0006411616 & 9.773172e-05 & 0.0002105587 & 0.0038085032 & 0.004627804\\\\\n",
       "\tTCGA.CV.7261.01A & 3.942927e-05 & 2.204710e-05 & 2.044807e-04 & 0.0011940780 & 1.745750e-04 & 7.122713e-05 & 4.453275e-04 & 0.0002607408 & 1.000000e-08 & 1e-08 & ⋯ & 0.003258928 & 0.0004946441 & 0.0011090316 & 0.0016310078 & 0.0012178321 & 0.0004925674 & 6.676863e-05 & 0.0001493141 & 0.0172405230 & 0.002004587\\\\\n",
       "\tTCGA.CN.4736.01A & 1.390749e-05 & 8.769088e-07 & 1.223342e-04 & 0.0003837442 & 2.142997e-04 & 6.283548e-05 & 1.596004e-05 & 0.0004530299 & 1.000000e-08 & 1e-08 & ⋯ & 0.002296859 & 0.0001688855 & 0.0031227601 & 0.0023390499 & 0.0008105389 & 0.0001891924 & 1.701151e-04 & 0.0009726216 & 0.0386288860 & 0.001846247\\\\\n",
       "\tTCGA.CR.7404.01A & 6.644734e-05 & 2.869323e-05 & 2.431157e-04 & 0.0006640946 & 3.876657e-04 & 3.220030e-04 & 4.117645e-04 & 0.0004241875 & 1.000000e-08 & 1e-08 & ⋯ & 0.003802623 & 0.0003162880 & 0.0035471866 & 0.0058780413 & 0.0008346040 & 0.0004172660 & 3.501289e-04 & 0.0001747886 & 0.0043973878 & 0.002804166\\\\\n",
       "\tTCGA.UF.A719.01A & 5.100094e-05 & 4.090135e-05 & 8.886602e-05 & 0.0005454100 & 2.660999e-04 & 3.933922e-05 & 1.057499e-04 & 0.0006982935 & 1.265862e-07 & 1e-08 & ⋯ & 0.003819092 & 0.0005531189 & 0.0034956357 & 0.0108619360 & 0.0004804429 & 0.0004463037 & 1.825883e-04 & 0.0002105398 & 0.0061043322 & 0.002410001\\\\\n",
       "\tTCGA.CV.7236.01A & 3.252200e-05 & 5.488452e-06 & 1.092472e-04 & 0.0003468501 & 1.309125e-04 & 5.986113e-05 & 3.696085e-05 & 0.0002600968 & 1.000000e-08 & 1e-08 & ⋯ & 0.006065872 & 0.0002268857 & 0.0027198014 & 0.0005824110 & 0.0008134314 & 0.0002646659 & 1.159172e-04 & 0.0008765738 & 0.0277032892 & 0.003632712\\\\\n",
       "\tTCGA.CV.6951.01A & 1.005896e-05 & 6.093762e-06 & 1.052292e-04 & 0.0003327380 & 2.115928e-04 & 2.419086e-05 & 1.306260e-05 & 0.0005985506 & 1.000000e-08 & 1e-08 & ⋯ & 0.003143431 & 0.0003646987 & 0.0025639218 & 0.0020115784 & 0.0012760151 & 0.0003109368 & 9.188377e-05 & 0.0002664351 & 0.0191011166 & 0.003565509\\\\\n",
       "\tTCGA.CN.4728.01A & 2.228636e-05 & 1.355492e-05 & 1.684279e-04 & 0.0005285901 & 2.218801e-04 & 3.632771e-05 & 8.188667e-05 & 0.0002971218 & 1.000000e-08 & 1e-08 & ⋯ & 0.004889457 & 0.0002230085 & 0.0029011805 & 0.0052395438 & 0.0004271121 & 0.0002519848 & 1.238790e-04 & 0.0006565699 & 0.0325675873 & 0.002063437\\\\\n",
       "\tTCGA.CV.7090.01A & 1.348566e-05 & 2.360787e-06 & 1.571082e-04 & 0.0003596658 & 1.054820e-04 & 2.264753e-05 & 9.385449e-06 & 0.0003380583 & 1.000000e-08 & 1e-08 & ⋯ & 0.003985342 & 0.0001846142 & 0.0017219079 & 0.0010546015 & 0.0005727302 & 0.0002025254 & 5.760173e-05 & 0.0002389454 & 0.0243289623 & 0.002574986\\\\\n",
       "\tTCGA.CV.5979.01A & 1.985399e-06 & 1.624909e-06 & 9.627707e-05 & 0.0005035822 & 5.120770e-05 & 1.299737e-05 & 4.211574e-06 & 0.0003494897 & 8.458415e-08 & 1e-08 & ⋯ & 0.009375253 & 0.0002882151 & 0.0009895547 & 0.0014856896 & 0.0004415379 & 0.0002778468 & 3.733991e-05 & 0.0005769098 & 0.0267583905 & 0.002554498\\\\\n",
       "\tTCGA.CQ.7069.01A & 1.186905e-05 & 6.942541e-06 & 7.473759e-05 & 0.0002819953 & 1.390721e-04 & 2.762522e-05 & 4.101573e-06 & 0.0004693662 & 1.000000e-08 & 1e-08 & ⋯ & 0.005293376 & 0.0001213396 & 0.0021885387 & 0.0015807052 & 0.0005381306 & 0.0001384772 & 2.787824e-05 & 0.0002499133 & 0.0364606068 & 0.002397554\\\\\n",
       "\tTCGA.CN.4733.01A & 6.843495e-05 & 1.363237e-05 & 6.723509e-04 & 0.0012068362 & 5.583519e-04 & 6.333076e-04 & 2.022035e-04 & 0.0004555842 & 1.000000e-08 & 1e-08 & ⋯ & 0.002585773 & 0.0002927561 & 0.0011298140 & 0.0013298247 & 0.0004118300 & 0.0003140261 & 1.196029e-04 & 0.0003824203 & 0.0179908098 & 0.002058683\\\\\n",
       "\tTCGA.CR.7390.01A & 1.012182e-05 & 2.742299e-06 & 9.313826e-05 & 0.0004419969 & 8.526116e-05 & 1.848770e-05 & 2.279696e-05 & 0.0002935566 & 1.000000e-08 & 1e-08 & ⋯ & 0.003986079 & 0.0002778338 & 0.0024745965 & 0.0032429093 & 0.0004728013 & 0.0001709763 & 4.543200e-05 & 0.0003704545 & 0.0225988761 & 0.002880202\\\\\n",
       "\tTCGA.CV.A45X.01A & 1.982327e-05 & 1.852276e-05 & 1.147817e-04 & 0.0003150305 & 1.603280e-04 & 1.857990e-05 & 2.948244e-05 & 0.0003965018 & 1.000000e-08 & 1e-08 & ⋯ & 0.005119607 & 0.0002482347 & 0.0037442767 & 0.0094928233 & 0.0002827414 & 0.0002545380 & 7.346472e-05 & 0.0002453223 & 0.0181047634 & 0.005153022\\\\\n",
       "\tTCGA.IQ.A6SH.01A & 5.290873e-05 & 2.686428e-05 & 2.361949e-04 & 0.0005290442 & 1.773073e-04 & 3.919241e-05 & 2.574518e-04 & 0.0010084499 & 1.000000e-08 & 1e-08 & ⋯ & 0.006610426 & 0.0004966262 & 0.0017259967 & 0.0029736185 & 0.0002355422 & 0.0004633796 & 8.418996e-05 & 0.0003543382 & 0.0480659416 & 0.004541411\\\\\n",
       "\tTCGA.CV.6962.11A & 2.605594e-05 & 1.430024e-05 & 7.174069e-05 & 0.0003952625 & 1.381772e-04 & 5.441342e-05 & 1.668698e-04 & 0.0002953859 & 1.000000e-08 & 1e-08 & ⋯ & 0.006503971 & 0.0001457363 & 0.0051940113 & 0.0194390703 & 0.0002386599 & 0.0001966075 & 1.001317e-04 & 0.0004664489 & 0.0064596702 & 0.002182135\\\\\n",
       "\tTCGA.CV.6960.11A & 5.507670e-06 & 6.364167e-06 & 8.184837e-05 & 0.0006173584 & 1.908321e-04 & 5.381925e-05 & 1.531101e-05 & 0.0002441374 & 1.000000e-08 & 1e-08 & ⋯ & 0.006409453 & 0.0002095843 & 0.0028872163 & 0.0110644614 & 0.0004092271 & 0.0002899279 & 7.510687e-05 & 0.0002899852 & 0.0061605791 & 0.002550240\\\\\n",
       "\tTCGA.CV.A464.01A & 1.827661e-05 & 2.765335e-06 & 1.891166e-04 & 0.0005600828 & 2.327449e-04 & 2.054429e-05 & 1.001617e-05 & 0.0004629118 & 1.000000e-08 & 1e-08 & ⋯ & 0.004771309 & 0.0003365614 & 0.0021381656 & 0.0012481794 & 0.0006264352 & 0.0004487420 & 7.497420e-05 & 0.0005972093 & 0.0293922083 & 0.002852930\\\\\n",
       "\tTCGA.C9.A47Z.01A & 8.938936e-06 & 4.649978e-06 & 8.093006e-05 & 0.0003100898 & 1.004789e-04 & 1.261151e-05 & 1.596038e-05 & 0.0002968109 & 1.000000e-08 & 1e-08 & ⋯ & 0.002239680 & 0.0001309478 & 0.0015309809 & 0.0059378962 & 0.0006212079 & 0.0001875071 & 7.887333e-05 & 0.0005531027 & 0.0992483984 & 0.002564241\\\\\n",
       "\tTCGA.CN.6010.01A & 2.089121e-05 & 1.334562e-05 & 2.763071e-04 & 0.0012088467 & 2.459090e-04 & 2.192413e-04 & 2.586062e-04 & 0.0003568362 & 1.624118e-08 & 1e-08 & ⋯ & 0.003840012 & 0.0004233957 & 0.0021606340 & 0.0007145344 & 0.0015495287 & 0.0005200101 & 8.844130e-05 & 0.0002229744 & 0.0082722783 & 0.002362312\\\\\n",
       "\tTCGA.WA.A7GZ.11A & 7.893354e-07 & 4.370099e-08 & 1.080259e-04 & 0.0005148579 & 2.727584e-04 & 3.413857e-05 & 1.995681e-07 & 0.0002593855 & 1.000000e-08 & 1e-08 & ⋯ & 0.003282486 & 0.0002161534 & 0.0053297142 & 0.0489133412 & 0.0004428642 & 0.0002246060 & 4.091036e-05 & 0.0007222012 & 0.0020397140 & 0.001236956\\\\\n",
       "\tTCGA.CV.7235.01A & 2.601504e-06 & 1.517452e-06 & 1.119294e-04 & 0.0002247817 & 8.398276e-05 & 3.821899e-05 & 5.479168e-06 & 0.0003393481 & 1.000000e-08 & 1e-08 & ⋯ & 0.004799518 & 0.0002369377 & 0.0015920840 & 0.0001192039 & 0.0006553211 & 0.0002931653 & 6.543051e-05 & 0.0002908468 & 0.0007669689 & 0.003346472\\\\\n",
       "\tTCGA.CX.7086.01A & 4.055162e-05 & 2.509406e-05 & 9.185760e-05 & 0.0007694788 & 1.362761e-04 & 7.474478e-05 & 2.588934e-04 & 0.0002799019 & 1.000000e-08 & 1e-08 & ⋯ & 0.002860567 & 0.0002871156 & 0.0020469296 & 0.0110965045 & 0.0004396349 & 0.0003355767 & 3.549545e-05 & 0.0002100881 & 0.0338536139 & 0.003258462\\\\\n",
       "\tTCGA.CV.6935.11A & 1.386939e-05 & 1.191753e-05 & 8.580734e-05 & 0.0004130733 & 2.043172e-04 & 8.868809e-05 & 7.729184e-05 & 0.0002672378 & 1.000000e-08 & 1e-08 & ⋯ & 0.004900983 & 0.0001527211 & 0.0033053024 & 0.0186461451 & 0.0003531671 & 0.0002227639 & 5.020764e-05 & 0.0002912144 & 0.0094543972 & 0.002323451\\\\\n",
       "\tTCGA.P3.A6SW.01A & 6.539912e-05 & 2.987839e-05 & 7.046281e-04 & 0.0020177067 & 5.459469e-04 & 2.847305e-04 & 3.736049e-04 & 0.0007576098 & 1.000000e-08 & 1e-08 & ⋯ & 0.005294263 & 0.0008564356 & 0.0038805225 & 0.0054065055 & 0.0005171346 & 0.0009597469 & 1.195716e-04 & 0.0003468781 & 0.0036510506 & 0.006277217\\\\\n",
       "\tTCGA.HD.A6HZ.01A & 3.281303e-05 & 9.207355e-06 & 2.755016e-04 & 0.0007267136 & 1.949370e-04 & 1.929092e-04 & 5.411360e-04 & 0.0002785809 & 1.000000e-08 & 1e-08 & ⋯ & 0.006158281 & 0.0003242550 & 0.0018518827 & 0.0028840979 & 0.0009633043 & 0.0003997828 & 1.216862e-04 & 0.0003307637 & 0.0263178340 & 0.002522418\\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "A matrix: 546 × 760 of type dbl\n",
       "\n",
       "| <!--/--> | ENSG00000170476 | ENSG00000099958 | ENSG00000134285 | ENSG00000051108 | ENSG00000166562 | ENSG00000183508 | ENSG00000254709 | ENSG00000173486 | ENSG00000213140 | ENSG00000100219 | ⋯ | ENSG00000197747 | ENSG00000182004 | ENSG00000166145 | ENSG00000121552 | ENSG00000139324 | ENSG00000139343 | ENSG00000237945 | ENSG00000264230 | ENSG00000185479 | ENSG00000196262 |\n",
       "|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|\n",
       "| TCGA.BB.4224.01A | 2.049247e-06 | 8.278036e-06 | 7.993074e-05 | 0.0003016311 | 1.789655e-04 | 7.214426e-06 | 3.616179e-06 | 0.0003700216 | 1.628714e-07 | 1e-08 | ⋯ | 0.002737765 | 5.773484e-04 | 0.0017739162 | 0.0089543412 | 0.0008018141 | 6.692068e-04 | 2.308098e-04 | 4.367240e-04 | 0.009079472 | 0.013460871 |\n",
       "| TCGA.H7.7774.01A | 1.456508e-05 | 1.659493e-05 | 3.901972e-05 | 0.0003040131 | 1.257976e-04 | 2.986419e-05 | 9.902832e-05 | 0.0002230157 | 1.000000e-08 | 1e-08 | ⋯ | 0.003337577 | 1.433087e-04 | 0.0014243026 | 0.0166559084 | 0.0005140027 | 3.059268e-04 | 5.841788e-05 | 3.626587e-04 | 0.084561644 | 0.002045631 |\n",
       "| TCGA.CV.6943.01A | 7.706264e-05 | 2.317288e-05 | 1.919155e-04 | 0.0003806151 | 1.568517e-04 | 9.695148e-05 | 4.693725e-04 | 0.0002469867 | 1.000000e-08 | 1e-08 | ⋯ | 0.003357789 | 1.559257e-04 | 0.0038717172 | 0.0024351945 | 0.0004150751 | 1.871413e-04 | 1.157592e-04 | 5.567893e-04 | 0.054130245 | 0.001652089 |\n",
       "| TCGA.CN.5374.01A | 2.662188e-05 | 2.049187e-05 | 2.066638e-04 | 0.0005088117 | 2.908512e-04 | 1.100708e-04 | 3.181145e-04 | 0.0005197946 | 1.000000e-08 | 1e-08 | ⋯ | 0.010330342 | 4.239480e-04 | 0.0050937505 | 0.0026178135 | 0.0003574237 | 5.400711e-04 | 2.654795e-05 | 3.842901e-04 | 0.002485788 | 0.002593591 |\n",
       "| TCGA.CQ.6227.01A | 2.593107e-05 | 1.036527e-06 | 1.790201e-04 | 0.0004976070 | 2.497173e-04 | 2.936631e-05 | 1.234068e-05 | 0.0005737245 | 1.000000e-08 | 1e-08 | ⋯ | 0.004530666 | 2.386463e-04 | 0.0017714377 | 0.0053466289 | 0.0005887246 | 2.386188e-04 | 1.066649e-04 | 4.524921e-04 | 0.030182147 | 0.002398836 |\n",
       "| TCGA.CV.6959.01A | 6.961463e-05 | 2.727789e-06 | 1.352284e-04 | 0.0004187407 | 1.303890e-04 | 1.003146e-04 | 1.818100e-04 | 0.0002814092 | 1.000000e-08 | 1e-08 | ⋯ | 0.004082648 | 2.200997e-04 | 0.0013295819 | 0.0023046395 | 0.0004808925 | 3.583344e-04 | 7.808572e-05 | 3.079049e-04 | 0.029175120 | 0.002409821 |\n",
       "| TCGA.F7.A61V.01A | 2.830645e-05 | 7.561233e-06 | 1.369668e-04 | 0.0005038926 | 2.715256e-04 | 6.540110e-05 | 8.356970e-05 | 0.0006785771 | 1.000000e-08 | 1e-08 | ⋯ | 0.005626857 | 4.308986e-04 | 0.0022317165 | 0.0323772297 | 0.0004708252 | 5.992306e-04 | 1.352416e-05 | 2.127113e-04 | 0.032960660 | 0.004283686 |\n",
       "| TCGA.CV.7413.01A | 1.785685e-05 | 5.282712e-06 | 1.218923e-04 | 0.0003108130 | 1.169820e-04 | 1.764722e-05 | 2.682257e-05 | 0.0003967018 | 1.000000e-08 | 1e-08 | ⋯ | 0.004879131 | 2.800998e-04 | 0.0037563555 | 0.0017821653 | 0.0005171505 | 3.428029e-04 | 1.394460e-04 | 3.722275e-04 | 0.038769554 | 0.002416373 |\n",
       "| TCGA.CV.7247.01A | 3.811184e-06 | 4.289529e-07 | 1.450429e-04 | 0.0003171369 | 8.909711e-05 | 2.454457e-05 | 2.104127e-06 | 0.0002724595 | 1.000000e-08 | 1e-08 | ⋯ | 0.005585513 | 3.754058e-04 | 0.0020373186 | 0.0029178676 | 0.0009947036 | 4.143002e-04 | 1.677187e-04 | 5.068920e-04 | 0.021828081 | 0.004925209 |\n",
       "| TCGA.CR.5249.01A | 4.528438e-05 | 1.810596e-05 | 2.477341e-04 | 0.0007866894 | 2.952037e-04 | 3.301050e-04 | 3.166782e-04 | 0.0002964787 | 1.000000e-08 | 1e-08 | ⋯ | 0.002960998 | 1.687711e-04 | 0.0031681877 | 0.0034204397 | 0.0010516075 | 1.980024e-04 | 1.816146e-04 | 5.952634e-04 | 0.011545750 | 0.002209561 |\n",
       "| TCGA.CQ.5331.01A | 9.156581e-05 | 2.989494e-05 | 2.648125e-04 | 0.0004223396 | 1.583459e-04 | 1.046004e-04 | 1.017654e-04 | 0.0002813868 | 1.000000e-08 | 1e-08 | ⋯ | 0.002116966 | 2.158482e-04 | 0.0008185703 | 0.0104473836 | 0.0004349681 | 2.344521e-04 | 6.835260e-05 | 2.280540e-04 | 0.073982929 | 0.002414117 |\n",
       "| TCGA.BB.8601.01A | 1.051602e-04 | 6.888089e-05 | 1.366950e-04 | 0.0004107444 | 2.341090e-04 | 4.878925e-05 | 4.327599e-04 | 0.0004442685 | 1.000000e-08 | 1e-08 | ⋯ | 0.005941892 | 7.148520e-04 | 0.0013883150 | 0.0072199093 | 0.0012015445 | 7.152516e-04 | 4.785123e-05 | 2.400354e-04 | 0.018089630 | 0.006423278 |\n",
       "| TCGA.CV.A45W.01A | 4.032253e-05 | 1.702758e-05 | 7.340113e-04 | 0.0019683746 | 5.485908e-04 | 3.918964e-04 | 6.717086e-04 | 0.0008967767 | 1.000000e-08 | 1e-08 | ⋯ | 0.001917906 | 3.920446e-04 | 0.0019031008 | 0.0051938047 | 0.0007790055 | 5.906361e-04 | 8.620462e-05 | 6.646666e-05 | 0.002525816 | 0.003339710 |\n",
       "| TCGA.CQ.7063.01A | 1.235255e-05 | 9.993016e-06 | 1.319633e-04 | 0.0002852475 | 8.989533e-05 | 6.044874e-05 | 6.918289e-06 | 0.0002003570 | 1.000000e-08 | 1e-08 | ⋯ | 0.003398543 | 1.586570e-04 | 0.0017012382 | 0.0032522460 | 0.0003016946 | 1.823135e-04 | 8.863041e-05 | 4.228896e-04 | 0.047377067 | 0.002186628 |\n",
       "| TCGA.CN.5373.01A | 1.715681e-05 | 7.226266e-06 | 6.552594e-05 | 0.0002729102 | 7.044489e-05 | 4.893205e-05 | 3.333021e-05 | 0.0002322776 | 1.000000e-08 | 1e-08 | ⋯ | 0.001655155 | 8.016141e-05 | 0.0016525510 | 0.0055143119 | 0.0005213437 | 9.728658e-05 | 8.536740e-05 | 4.841650e-04 | 0.110119547 | 0.001424400 |\n",
       "| TCGA.CV.A45T.01A | 6.744023e-05 | 2.018933e-05 | 2.490121e-04 | 0.0007053947 | 2.222814e-04 | 1.527868e-04 | 3.268788e-04 | 0.0004819631 | 1.000000e-08 | 1e-08 | ⋯ | 0.004611893 | 3.322539e-04 | 0.0011057098 | 0.0113060985 | 0.0002201174 | 3.553431e-04 | 5.015535e-05 | 4.797819e-04 | 0.073378459 | 0.003104214 |\n",
       "| TCGA.HD.A4C1.01A | 1.099770e-04 | 1.750373e-05 | 2.098977e-04 | 0.0002674171 | 2.119277e-04 | 6.504464e-05 | 1.552979e-04 | 0.0002556994 | 1.000000e-08 | 1e-08 | ⋯ | 0.004476140 | 2.377950e-04 | 0.0017209266 | 0.0049206500 | 0.0007088569 | 2.931246e-04 | 7.256049e-05 | 3.215368e-04 | 0.041926520 | 0.002846415 |\n",
       "| TCGA.CV.7438.11A | 5.050969e-05 | 1.716479e-05 | 1.153985e-04 | 0.0005002833 | 2.024119e-04 | 9.751444e-05 | 3.473233e-04 | 0.0002890306 | 1.000000e-08 | 1e-08 | ⋯ | 0.004479447 | 2.357138e-04 | 0.0018305646 | 0.0154356225 | 0.0002963051 | 3.234816e-04 | 7.462886e-05 | 4.099938e-04 | 0.036995445 | 0.002871761 |\n",
       "| TCGA.CV.5444.01A | 1.340258e-05 | 4.642889e-06 | 1.849706e-04 | 0.0003104101 | 1.044504e-04 | 2.606660e-05 | 2.521237e-05 | 0.0004050447 | 1.000000e-08 | 1e-08 | ⋯ | 0.003810114 | 2.579929e-04 | 0.0026027185 | 0.0020095220 | 0.0004906207 | 3.024435e-04 | 1.801730e-04 | 7.470174e-04 | 0.020614277 | 0.002462434 |\n",
       "| TCGA.BA.5556.01A | 6.395396e-05 | 2.613957e-05 | 1.610629e-04 | 0.0003802627 | 1.302612e-04 | 1.518540e-04 | 2.494859e-04 | 0.0002640489 | 1.000000e-08 | 1e-08 | ⋯ | 0.003600573 | 1.634347e-04 | 0.0018362387 | 0.0028587916 | 0.0003777037 | 2.260585e-04 | 1.605390e-04 | 4.405382e-04 | 0.032918689 | 0.002362555 |\n",
       "| TCGA.P3.A6SX.01A | 1.625000e-05 | 7.765744e-06 | 1.025321e-04 | 0.0003100384 | 2.586142e-04 | 1.561991e-05 | 4.604509e-06 | 0.0008899720 | 1.000000e-08 | 1e-08 | ⋯ | 0.006280771 | 5.346874e-04 | 0.0023197761 | 0.0022712824 | 0.0005605644 | 5.489885e-04 | 6.276184e-05 | 1.764815e-04 | 0.036640466 | 0.004356166 |\n",
       "| TCGA.CV.7242.11A | 1.961195e-05 | 8.839838e-06 | 1.255808e-04 | 0.0004825937 | 2.408144e-04 | 5.441852e-05 | 4.136964e-05 | 0.0003709810 | 1.000000e-08 | 1e-08 | ⋯ | 0.007369572 | 3.025168e-04 | 0.0032612093 | 0.0200354832 | 0.0002793075 | 4.638789e-04 | 5.193720e-05 | 2.945520e-04 | 0.002345791 | 0.003399956 |\n",
       "| TCGA.DQ.7592.01A | 1.305065e-05 | 6.278095e-06 | 1.836021e-04 | 0.0007367294 | 1.138705e-04 | 1.768199e-05 | 2.142013e-05 | 0.0002584084 | 5.705522e-08 | 1e-08 | ⋯ | 0.003336019 | 2.514070e-04 | 0.0032934795 | 0.0018629622 | 0.0005402061 | 2.796855e-04 | 8.865398e-05 | 3.579947e-04 | 0.009928997 | 0.003024097 |\n",
       "| TCGA.CV.6937.01A | 7.414205e-06 | 3.730424e-06 | 1.301218e-04 | 0.0003976488 | 2.396035e-04 | 4.740898e-04 | 8.759695e-06 | 0.0003191809 | 1.000000e-08 | 1e-08 | ⋯ | 0.004346442 | 5.132510e-04 | 0.0023996582 | 0.0009491521 | 0.0003516651 | 3.318331e-04 | 6.027308e-05 | 6.927646e-04 | 0.004763760 | 0.003762372 |\n",
       "| TCGA.QK.A8ZB.01A | 7.380388e-05 | 4.081921e-05 | 3.902980e-04 | 0.0011514768 | 3.315389e-04 | 2.744386e-04 | 6.930245e-04 | 0.0005834410 | 1.000000e-08 | 1e-08 | ⋯ | 0.002897496 | 2.532544e-04 | 0.0017825461 | 0.0130022214 | 0.0004766300 | 3.081891e-04 | 1.585205e-04 | 7.080066e-04 | 0.034975994 | 0.002742837 |\n",
       "| TCGA.CV.7432.01A | 1.995097e-06 | 9.091119e-06 | 1.621309e-04 | 0.0002019652 | 1.766631e-04 | 1.472208e-05 | 1.400034e-06 | 0.0005102209 | 1.000000e-08 | 1e-08 | ⋯ | 0.006701766 | 3.634160e-04 | 0.0007841787 | 0.0012932573 | 0.0005436148 | 3.844492e-04 | 8.900618e-05 | 5.164222e-04 | 0.020327529 | 0.004136221 |\n",
       "| TCGA.CV.7089.01A | 1.205463e-05 | 8.519127e-06 | 8.186953e-05 | 0.0002950473 | 9.073284e-05 | 2.605794e-05 | 2.554719e-05 | 0.0002767261 | 1.000000e-08 | 1e-08 | ⋯ | 0.007622057 | 2.258614e-04 | 0.0018506403 | 0.0101614970 | 0.0003772263 | 3.286588e-04 | 6.041428e-05 | 4.450423e-04 | 0.028509745 | 0.002970316 |\n",
       "| TCGA.CV.6939.11A | 1.000000e-08 | 1.000000e-08 | 6.882360e-04 | 0.0024088011 | 1.376462e-03 | 1.000000e-08 | 1.000000e-08 | 0.0003441230 | 1.000000e-08 | 1e-08 | ⋯ | 0.000344123 | 1.032349e-03 | 0.0223673555 | 0.0048175921 | 0.0003441230 | 3.441230e-04 | 1.000000e-08 | 1.000000e-08 | 0.000344123 | 0.000344123 |\n",
       "| TCGA.BA.4075.01A | 9.427073e-07 | 4.890226e-06 | 2.629682e-04 | 0.0005298174 | 1.574309e-04 | 5.007992e-06 | 4.625084e-06 | 0.0002565718 | 1.000000e-08 | 1e-08 | ⋯ | 0.008498127 | 6.507726e-04 | 0.0008981257 | 0.0017960672 | 0.0002748242 | 3.098169e-04 | 9.336014e-05 | 5.669379e-04 | 0.004266577 | 0.012449356 |\n",
       "| TCGA.T3.A92M.01A | 9.909917e-05 | 3.355913e-05 | 3.052128e-04 | 0.0008003329 | 3.846975e-04 | 1.233704e-04 | 4.426472e-04 | 0.0004964614 | 1.000000e-08 | 1e-08 | ⋯ | 0.004055301 | 6.537091e-04 | 0.0017117580 | 0.0015475192 | 0.0006276969 | 1.026578e-03 | 9.259499e-05 | 3.069821e-04 | 0.007744020 | 0.003446403 |\n",
       "| ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋱ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ |\n",
       "| TCGA.CV.7430.01A | 8.104140e-06 | 5.776797e-06 | 6.750206e-05 | 0.0002853851 | 9.439273e-05 | 1.941104e-05 | 2.524718e-05 | 0.0002446748 | 1.000000e-08 | 1e-08 | ⋯ | 0.007121540 | 0.0002895846 | 0.0036654498 | 0.0048225068 | 0.0006275938 | 0.0003736934 | 4.550609e-05 | 0.0005383872 | 0.0145368126 | 0.001343983 |\n",
       "| TCGA.D6.A74Q.01A | 5.337087e-05 | 2.874010e-05 | 3.116200e-04 | 0.0007130012 | 1.958654e-04 | 1.671915e-04 | 5.210625e-04 | 0.0006809090 | 1.000000e-08 | 1e-08 | ⋯ | 0.005756178 | 0.0006227999 | 0.0019739963 | 0.0054332114 | 0.0006227270 | 0.0007671214 | 7.493450e-05 | 0.0004953226 | 0.0095378436 | 0.005052232 |\n",
       "| TCGA.CV.7255.01A | 5.878292e-06 | 1.421801e-06 | 4.910690e-05 | 0.0002940495 | 1.313624e-04 | 1.057609e-05 | 2.235211e-05 | 0.0005886989 | 1.000000e-08 | 1e-08 | ⋯ | 0.005428264 | 0.0002686081 | 0.0025571581 | 0.0021710324 | 0.0003400059 | 0.0001293436 | 1.606496e-04 | 0.0006389083 | 0.0108127902 | 0.003692008 |\n",
       "| TCGA.CQ.6223.01A | 4.435995e-05 | 4.009854e-05 | 6.211937e-05 | 0.0004650225 | 7.399283e-05 | 7.493441e-05 | 1.756797e-04 | 0.0002270226 | 1.000000e-08 | 1e-08 | ⋯ | 0.003053088 | 0.0001634606 | 0.0022289593 | 0.0077123084 | 0.0004166915 | 0.0002387974 | 4.522391e-05 | 0.0002499937 | 0.0602492184 | 0.002551418 |\n",
       "| TCGA.CV.A460.01A | 5.011232e-05 | 3.603755e-05 | 2.293757e-04 | 0.0009944662 | 3.764719e-04 | 1.673545e-04 | 4.979068e-04 | 0.0005998793 | 1.000000e-08 | 1e-08 | ⋯ | 0.003110662 | 0.0004130311 | 0.0023860029 | 0.0026728659 | 0.0006409095 | 0.0006411616 | 9.773172e-05 | 0.0002105587 | 0.0038085032 | 0.004627804 |\n",
       "| TCGA.CV.7261.01A | 3.942927e-05 | 2.204710e-05 | 2.044807e-04 | 0.0011940780 | 1.745750e-04 | 7.122713e-05 | 4.453275e-04 | 0.0002607408 | 1.000000e-08 | 1e-08 | ⋯ | 0.003258928 | 0.0004946441 | 0.0011090316 | 0.0016310078 | 0.0012178321 | 0.0004925674 | 6.676863e-05 | 0.0001493141 | 0.0172405230 | 0.002004587 |\n",
       "| TCGA.CN.4736.01A | 1.390749e-05 | 8.769088e-07 | 1.223342e-04 | 0.0003837442 | 2.142997e-04 | 6.283548e-05 | 1.596004e-05 | 0.0004530299 | 1.000000e-08 | 1e-08 | ⋯ | 0.002296859 | 0.0001688855 | 0.0031227601 | 0.0023390499 | 0.0008105389 | 0.0001891924 | 1.701151e-04 | 0.0009726216 | 0.0386288860 | 0.001846247 |\n",
       "| TCGA.CR.7404.01A | 6.644734e-05 | 2.869323e-05 | 2.431157e-04 | 0.0006640946 | 3.876657e-04 | 3.220030e-04 | 4.117645e-04 | 0.0004241875 | 1.000000e-08 | 1e-08 | ⋯ | 0.003802623 | 0.0003162880 | 0.0035471866 | 0.0058780413 | 0.0008346040 | 0.0004172660 | 3.501289e-04 | 0.0001747886 | 0.0043973878 | 0.002804166 |\n",
       "| TCGA.UF.A719.01A | 5.100094e-05 | 4.090135e-05 | 8.886602e-05 | 0.0005454100 | 2.660999e-04 | 3.933922e-05 | 1.057499e-04 | 0.0006982935 | 1.265862e-07 | 1e-08 | ⋯ | 0.003819092 | 0.0005531189 | 0.0034956357 | 0.0108619360 | 0.0004804429 | 0.0004463037 | 1.825883e-04 | 0.0002105398 | 0.0061043322 | 0.002410001 |\n",
       "| TCGA.CV.7236.01A | 3.252200e-05 | 5.488452e-06 | 1.092472e-04 | 0.0003468501 | 1.309125e-04 | 5.986113e-05 | 3.696085e-05 | 0.0002600968 | 1.000000e-08 | 1e-08 | ⋯ | 0.006065872 | 0.0002268857 | 0.0027198014 | 0.0005824110 | 0.0008134314 | 0.0002646659 | 1.159172e-04 | 0.0008765738 | 0.0277032892 | 0.003632712 |\n",
       "| TCGA.CV.6951.01A | 1.005896e-05 | 6.093762e-06 | 1.052292e-04 | 0.0003327380 | 2.115928e-04 | 2.419086e-05 | 1.306260e-05 | 0.0005985506 | 1.000000e-08 | 1e-08 | ⋯ | 0.003143431 | 0.0003646987 | 0.0025639218 | 0.0020115784 | 0.0012760151 | 0.0003109368 | 9.188377e-05 | 0.0002664351 | 0.0191011166 | 0.003565509 |\n",
       "| TCGA.CN.4728.01A | 2.228636e-05 | 1.355492e-05 | 1.684279e-04 | 0.0005285901 | 2.218801e-04 | 3.632771e-05 | 8.188667e-05 | 0.0002971218 | 1.000000e-08 | 1e-08 | ⋯ | 0.004889457 | 0.0002230085 | 0.0029011805 | 0.0052395438 | 0.0004271121 | 0.0002519848 | 1.238790e-04 | 0.0006565699 | 0.0325675873 | 0.002063437 |\n",
       "| TCGA.CV.7090.01A | 1.348566e-05 | 2.360787e-06 | 1.571082e-04 | 0.0003596658 | 1.054820e-04 | 2.264753e-05 | 9.385449e-06 | 0.0003380583 | 1.000000e-08 | 1e-08 | ⋯ | 0.003985342 | 0.0001846142 | 0.0017219079 | 0.0010546015 | 0.0005727302 | 0.0002025254 | 5.760173e-05 | 0.0002389454 | 0.0243289623 | 0.002574986 |\n",
       "| TCGA.CV.5979.01A | 1.985399e-06 | 1.624909e-06 | 9.627707e-05 | 0.0005035822 | 5.120770e-05 | 1.299737e-05 | 4.211574e-06 | 0.0003494897 | 8.458415e-08 | 1e-08 | ⋯ | 0.009375253 | 0.0002882151 | 0.0009895547 | 0.0014856896 | 0.0004415379 | 0.0002778468 | 3.733991e-05 | 0.0005769098 | 0.0267583905 | 0.002554498 |\n",
       "| TCGA.CQ.7069.01A | 1.186905e-05 | 6.942541e-06 | 7.473759e-05 | 0.0002819953 | 1.390721e-04 | 2.762522e-05 | 4.101573e-06 | 0.0004693662 | 1.000000e-08 | 1e-08 | ⋯ | 0.005293376 | 0.0001213396 | 0.0021885387 | 0.0015807052 | 0.0005381306 | 0.0001384772 | 2.787824e-05 | 0.0002499133 | 0.0364606068 | 0.002397554 |\n",
       "| TCGA.CN.4733.01A | 6.843495e-05 | 1.363237e-05 | 6.723509e-04 | 0.0012068362 | 5.583519e-04 | 6.333076e-04 | 2.022035e-04 | 0.0004555842 | 1.000000e-08 | 1e-08 | ⋯ | 0.002585773 | 0.0002927561 | 0.0011298140 | 0.0013298247 | 0.0004118300 | 0.0003140261 | 1.196029e-04 | 0.0003824203 | 0.0179908098 | 0.002058683 |\n",
       "| TCGA.CR.7390.01A | 1.012182e-05 | 2.742299e-06 | 9.313826e-05 | 0.0004419969 | 8.526116e-05 | 1.848770e-05 | 2.279696e-05 | 0.0002935566 | 1.000000e-08 | 1e-08 | ⋯ | 0.003986079 | 0.0002778338 | 0.0024745965 | 0.0032429093 | 0.0004728013 | 0.0001709763 | 4.543200e-05 | 0.0003704545 | 0.0225988761 | 0.002880202 |\n",
       "| TCGA.CV.A45X.01A | 1.982327e-05 | 1.852276e-05 | 1.147817e-04 | 0.0003150305 | 1.603280e-04 | 1.857990e-05 | 2.948244e-05 | 0.0003965018 | 1.000000e-08 | 1e-08 | ⋯ | 0.005119607 | 0.0002482347 | 0.0037442767 | 0.0094928233 | 0.0002827414 | 0.0002545380 | 7.346472e-05 | 0.0002453223 | 0.0181047634 | 0.005153022 |\n",
       "| TCGA.IQ.A6SH.01A | 5.290873e-05 | 2.686428e-05 | 2.361949e-04 | 0.0005290442 | 1.773073e-04 | 3.919241e-05 | 2.574518e-04 | 0.0010084499 | 1.000000e-08 | 1e-08 | ⋯ | 0.006610426 | 0.0004966262 | 0.0017259967 | 0.0029736185 | 0.0002355422 | 0.0004633796 | 8.418996e-05 | 0.0003543382 | 0.0480659416 | 0.004541411 |\n",
       "| TCGA.CV.6962.11A | 2.605594e-05 | 1.430024e-05 | 7.174069e-05 | 0.0003952625 | 1.381772e-04 | 5.441342e-05 | 1.668698e-04 | 0.0002953859 | 1.000000e-08 | 1e-08 | ⋯ | 0.006503971 | 0.0001457363 | 0.0051940113 | 0.0194390703 | 0.0002386599 | 0.0001966075 | 1.001317e-04 | 0.0004664489 | 0.0064596702 | 0.002182135 |\n",
       "| TCGA.CV.6960.11A | 5.507670e-06 | 6.364167e-06 | 8.184837e-05 | 0.0006173584 | 1.908321e-04 | 5.381925e-05 | 1.531101e-05 | 0.0002441374 | 1.000000e-08 | 1e-08 | ⋯ | 0.006409453 | 0.0002095843 | 0.0028872163 | 0.0110644614 | 0.0004092271 | 0.0002899279 | 7.510687e-05 | 0.0002899852 | 0.0061605791 | 0.002550240 |\n",
       "| TCGA.CV.A464.01A | 1.827661e-05 | 2.765335e-06 | 1.891166e-04 | 0.0005600828 | 2.327449e-04 | 2.054429e-05 | 1.001617e-05 | 0.0004629118 | 1.000000e-08 | 1e-08 | ⋯ | 0.004771309 | 0.0003365614 | 0.0021381656 | 0.0012481794 | 0.0006264352 | 0.0004487420 | 7.497420e-05 | 0.0005972093 | 0.0293922083 | 0.002852930 |\n",
       "| TCGA.C9.A47Z.01A | 8.938936e-06 | 4.649978e-06 | 8.093006e-05 | 0.0003100898 | 1.004789e-04 | 1.261151e-05 | 1.596038e-05 | 0.0002968109 | 1.000000e-08 | 1e-08 | ⋯ | 0.002239680 | 0.0001309478 | 0.0015309809 | 0.0059378962 | 0.0006212079 | 0.0001875071 | 7.887333e-05 | 0.0005531027 | 0.0992483984 | 0.002564241 |\n",
       "| TCGA.CN.6010.01A | 2.089121e-05 | 1.334562e-05 | 2.763071e-04 | 0.0012088467 | 2.459090e-04 | 2.192413e-04 | 2.586062e-04 | 0.0003568362 | 1.624118e-08 | 1e-08 | ⋯ | 0.003840012 | 0.0004233957 | 0.0021606340 | 0.0007145344 | 0.0015495287 | 0.0005200101 | 8.844130e-05 | 0.0002229744 | 0.0082722783 | 0.002362312 |\n",
       "| TCGA.WA.A7GZ.11A | 7.893354e-07 | 4.370099e-08 | 1.080259e-04 | 0.0005148579 | 2.727584e-04 | 3.413857e-05 | 1.995681e-07 | 0.0002593855 | 1.000000e-08 | 1e-08 | ⋯ | 0.003282486 | 0.0002161534 | 0.0053297142 | 0.0489133412 | 0.0004428642 | 0.0002246060 | 4.091036e-05 | 0.0007222012 | 0.0020397140 | 0.001236956 |\n",
       "| TCGA.CV.7235.01A | 2.601504e-06 | 1.517452e-06 | 1.119294e-04 | 0.0002247817 | 8.398276e-05 | 3.821899e-05 | 5.479168e-06 | 0.0003393481 | 1.000000e-08 | 1e-08 | ⋯ | 0.004799518 | 0.0002369377 | 0.0015920840 | 0.0001192039 | 0.0006553211 | 0.0002931653 | 6.543051e-05 | 0.0002908468 | 0.0007669689 | 0.003346472 |\n",
       "| TCGA.CX.7086.01A | 4.055162e-05 | 2.509406e-05 | 9.185760e-05 | 0.0007694788 | 1.362761e-04 | 7.474478e-05 | 2.588934e-04 | 0.0002799019 | 1.000000e-08 | 1e-08 | ⋯ | 0.002860567 | 0.0002871156 | 0.0020469296 | 0.0110965045 | 0.0004396349 | 0.0003355767 | 3.549545e-05 | 0.0002100881 | 0.0338536139 | 0.003258462 |\n",
       "| TCGA.CV.6935.11A | 1.386939e-05 | 1.191753e-05 | 8.580734e-05 | 0.0004130733 | 2.043172e-04 | 8.868809e-05 | 7.729184e-05 | 0.0002672378 | 1.000000e-08 | 1e-08 | ⋯ | 0.004900983 | 0.0001527211 | 0.0033053024 | 0.0186461451 | 0.0003531671 | 0.0002227639 | 5.020764e-05 | 0.0002912144 | 0.0094543972 | 0.002323451 |\n",
       "| TCGA.P3.A6SW.01A | 6.539912e-05 | 2.987839e-05 | 7.046281e-04 | 0.0020177067 | 5.459469e-04 | 2.847305e-04 | 3.736049e-04 | 0.0007576098 | 1.000000e-08 | 1e-08 | ⋯ | 0.005294263 | 0.0008564356 | 0.0038805225 | 0.0054065055 | 0.0005171346 | 0.0009597469 | 1.195716e-04 | 0.0003468781 | 0.0036510506 | 0.006277217 |\n",
       "| TCGA.HD.A6HZ.01A | 3.281303e-05 | 9.207355e-06 | 2.755016e-04 | 0.0007267136 | 1.949370e-04 | 1.929092e-04 | 5.411360e-04 | 0.0002785809 | 1.000000e-08 | 1e-08 | ⋯ | 0.006158281 | 0.0003242550 | 0.0018518827 | 0.0028840979 | 0.0009633043 | 0.0003997828 | 1.216862e-04 | 0.0003307637 | 0.0263178340 | 0.002522418 |\n",
       "\n"
      ],
      "text/plain": [
       "                 ENSG00000170476 ENSG00000099958 ENSG00000134285\n",
       "TCGA.BB.4224.01A 2.049247e-06    8.278036e-06    7.993074e-05   \n",
       "TCGA.H7.7774.01A 1.456508e-05    1.659493e-05    3.901972e-05   \n",
       "TCGA.CV.6943.01A 7.706264e-05    2.317288e-05    1.919155e-04   \n",
       "TCGA.CN.5374.01A 2.662188e-05    2.049187e-05    2.066638e-04   \n",
       "TCGA.CQ.6227.01A 2.593107e-05    1.036527e-06    1.790201e-04   \n",
       "TCGA.CV.6959.01A 6.961463e-05    2.727789e-06    1.352284e-04   \n",
       "TCGA.F7.A61V.01A 2.830645e-05    7.561233e-06    1.369668e-04   \n",
       "TCGA.CV.7413.01A 1.785685e-05    5.282712e-06    1.218923e-04   \n",
       "TCGA.CV.7247.01A 3.811184e-06    4.289529e-07    1.450429e-04   \n",
       "TCGA.CR.5249.01A 4.528438e-05    1.810596e-05    2.477341e-04   \n",
       "TCGA.CQ.5331.01A 9.156581e-05    2.989494e-05    2.648125e-04   \n",
       "TCGA.BB.8601.01A 1.051602e-04    6.888089e-05    1.366950e-04   \n",
       "TCGA.CV.A45W.01A 4.032253e-05    1.702758e-05    7.340113e-04   \n",
       "TCGA.CQ.7063.01A 1.235255e-05    9.993016e-06    1.319633e-04   \n",
       "TCGA.CN.5373.01A 1.715681e-05    7.226266e-06    6.552594e-05   \n",
       "TCGA.CV.A45T.01A 6.744023e-05    2.018933e-05    2.490121e-04   \n",
       "TCGA.HD.A4C1.01A 1.099770e-04    1.750373e-05    2.098977e-04   \n",
       "TCGA.CV.7438.11A 5.050969e-05    1.716479e-05    1.153985e-04   \n",
       "TCGA.CV.5444.01A 1.340258e-05    4.642889e-06    1.849706e-04   \n",
       "TCGA.BA.5556.01A 6.395396e-05    2.613957e-05    1.610629e-04   \n",
       "TCGA.P3.A6SX.01A 1.625000e-05    7.765744e-06    1.025321e-04   \n",
       "TCGA.CV.7242.11A 1.961195e-05    8.839838e-06    1.255808e-04   \n",
       "TCGA.DQ.7592.01A 1.305065e-05    6.278095e-06    1.836021e-04   \n",
       "TCGA.CV.6937.01A 7.414205e-06    3.730424e-06    1.301218e-04   \n",
       "TCGA.QK.A8ZB.01A 7.380388e-05    4.081921e-05    3.902980e-04   \n",
       "TCGA.CV.7432.01A 1.995097e-06    9.091119e-06    1.621309e-04   \n",
       "TCGA.CV.7089.01A 1.205463e-05    8.519127e-06    8.186953e-05   \n",
       "TCGA.CV.6939.11A 1.000000e-08    1.000000e-08    6.882360e-04   \n",
       "TCGA.BA.4075.01A 9.427073e-07    4.890226e-06    2.629682e-04   \n",
       "TCGA.T3.A92M.01A 9.909917e-05    3.355913e-05    3.052128e-04   \n",
       "⋮                ⋮               ⋮               ⋮              \n",
       "TCGA.CV.7430.01A 8.104140e-06    5.776797e-06    6.750206e-05   \n",
       "TCGA.D6.A74Q.01A 5.337087e-05    2.874010e-05    3.116200e-04   \n",
       "TCGA.CV.7255.01A 5.878292e-06    1.421801e-06    4.910690e-05   \n",
       "TCGA.CQ.6223.01A 4.435995e-05    4.009854e-05    6.211937e-05   \n",
       "TCGA.CV.A460.01A 5.011232e-05    3.603755e-05    2.293757e-04   \n",
       "TCGA.CV.7261.01A 3.942927e-05    2.204710e-05    2.044807e-04   \n",
       "TCGA.CN.4736.01A 1.390749e-05    8.769088e-07    1.223342e-04   \n",
       "TCGA.CR.7404.01A 6.644734e-05    2.869323e-05    2.431157e-04   \n",
       "TCGA.UF.A719.01A 5.100094e-05    4.090135e-05    8.886602e-05   \n",
       "TCGA.CV.7236.01A 3.252200e-05    5.488452e-06    1.092472e-04   \n",
       "TCGA.CV.6951.01A 1.005896e-05    6.093762e-06    1.052292e-04   \n",
       "TCGA.CN.4728.01A 2.228636e-05    1.355492e-05    1.684279e-04   \n",
       "TCGA.CV.7090.01A 1.348566e-05    2.360787e-06    1.571082e-04   \n",
       "TCGA.CV.5979.01A 1.985399e-06    1.624909e-06    9.627707e-05   \n",
       "TCGA.CQ.7069.01A 1.186905e-05    6.942541e-06    7.473759e-05   \n",
       "TCGA.CN.4733.01A 6.843495e-05    1.363237e-05    6.723509e-04   \n",
       "TCGA.CR.7390.01A 1.012182e-05    2.742299e-06    9.313826e-05   \n",
       "TCGA.CV.A45X.01A 1.982327e-05    1.852276e-05    1.147817e-04   \n",
       "TCGA.IQ.A6SH.01A 5.290873e-05    2.686428e-05    2.361949e-04   \n",
       "TCGA.CV.6962.11A 2.605594e-05    1.430024e-05    7.174069e-05   \n",
       "TCGA.CV.6960.11A 5.507670e-06    6.364167e-06    8.184837e-05   \n",
       "TCGA.CV.A464.01A 1.827661e-05    2.765335e-06    1.891166e-04   \n",
       "TCGA.C9.A47Z.01A 8.938936e-06    4.649978e-06    8.093006e-05   \n",
       "TCGA.CN.6010.01A 2.089121e-05    1.334562e-05    2.763071e-04   \n",
       "TCGA.WA.A7GZ.11A 7.893354e-07    4.370099e-08    1.080259e-04   \n",
       "TCGA.CV.7235.01A 2.601504e-06    1.517452e-06    1.119294e-04   \n",
       "TCGA.CX.7086.01A 4.055162e-05    2.509406e-05    9.185760e-05   \n",
       "TCGA.CV.6935.11A 1.386939e-05    1.191753e-05    8.580734e-05   \n",
       "TCGA.P3.A6SW.01A 6.539912e-05    2.987839e-05    7.046281e-04   \n",
       "TCGA.HD.A6HZ.01A 3.281303e-05    9.207355e-06    2.755016e-04   \n",
       "                 ENSG00000051108 ENSG00000166562 ENSG00000183508\n",
       "TCGA.BB.4224.01A 0.0003016311    1.789655e-04    7.214426e-06   \n",
       "TCGA.H7.7774.01A 0.0003040131    1.257976e-04    2.986419e-05   \n",
       "TCGA.CV.6943.01A 0.0003806151    1.568517e-04    9.695148e-05   \n",
       "TCGA.CN.5374.01A 0.0005088117    2.908512e-04    1.100708e-04   \n",
       "TCGA.CQ.6227.01A 0.0004976070    2.497173e-04    2.936631e-05   \n",
       "TCGA.CV.6959.01A 0.0004187407    1.303890e-04    1.003146e-04   \n",
       "TCGA.F7.A61V.01A 0.0005038926    2.715256e-04    6.540110e-05   \n",
       "TCGA.CV.7413.01A 0.0003108130    1.169820e-04    1.764722e-05   \n",
       "TCGA.CV.7247.01A 0.0003171369    8.909711e-05    2.454457e-05   \n",
       "TCGA.CR.5249.01A 0.0007866894    2.952037e-04    3.301050e-04   \n",
       "TCGA.CQ.5331.01A 0.0004223396    1.583459e-04    1.046004e-04   \n",
       "TCGA.BB.8601.01A 0.0004107444    2.341090e-04    4.878925e-05   \n",
       "TCGA.CV.A45W.01A 0.0019683746    5.485908e-04    3.918964e-04   \n",
       "TCGA.CQ.7063.01A 0.0002852475    8.989533e-05    6.044874e-05   \n",
       "TCGA.CN.5373.01A 0.0002729102    7.044489e-05    4.893205e-05   \n",
       "TCGA.CV.A45T.01A 0.0007053947    2.222814e-04    1.527868e-04   \n",
       "TCGA.HD.A4C1.01A 0.0002674171    2.119277e-04    6.504464e-05   \n",
       "TCGA.CV.7438.11A 0.0005002833    2.024119e-04    9.751444e-05   \n",
       "TCGA.CV.5444.01A 0.0003104101    1.044504e-04    2.606660e-05   \n",
       "TCGA.BA.5556.01A 0.0003802627    1.302612e-04    1.518540e-04   \n",
       "TCGA.P3.A6SX.01A 0.0003100384    2.586142e-04    1.561991e-05   \n",
       "TCGA.CV.7242.11A 0.0004825937    2.408144e-04    5.441852e-05   \n",
       "TCGA.DQ.7592.01A 0.0007367294    1.138705e-04    1.768199e-05   \n",
       "TCGA.CV.6937.01A 0.0003976488    2.396035e-04    4.740898e-04   \n",
       "TCGA.QK.A8ZB.01A 0.0011514768    3.315389e-04    2.744386e-04   \n",
       "TCGA.CV.7432.01A 0.0002019652    1.766631e-04    1.472208e-05   \n",
       "TCGA.CV.7089.01A 0.0002950473    9.073284e-05    2.605794e-05   \n",
       "TCGA.CV.6939.11A 0.0024088011    1.376462e-03    1.000000e-08   \n",
       "TCGA.BA.4075.01A 0.0005298174    1.574309e-04    5.007992e-06   \n",
       "TCGA.T3.A92M.01A 0.0008003329    3.846975e-04    1.233704e-04   \n",
       "⋮                ⋮               ⋮               ⋮              \n",
       "TCGA.CV.7430.01A 0.0002853851    9.439273e-05    1.941104e-05   \n",
       "TCGA.D6.A74Q.01A 0.0007130012    1.958654e-04    1.671915e-04   \n",
       "TCGA.CV.7255.01A 0.0002940495    1.313624e-04    1.057609e-05   \n",
       "TCGA.CQ.6223.01A 0.0004650225    7.399283e-05    7.493441e-05   \n",
       "TCGA.CV.A460.01A 0.0009944662    3.764719e-04    1.673545e-04   \n",
       "TCGA.CV.7261.01A 0.0011940780    1.745750e-04    7.122713e-05   \n",
       "TCGA.CN.4736.01A 0.0003837442    2.142997e-04    6.283548e-05   \n",
       "TCGA.CR.7404.01A 0.0006640946    3.876657e-04    3.220030e-04   \n",
       "TCGA.UF.A719.01A 0.0005454100    2.660999e-04    3.933922e-05   \n",
       "TCGA.CV.7236.01A 0.0003468501    1.309125e-04    5.986113e-05   \n",
       "TCGA.CV.6951.01A 0.0003327380    2.115928e-04    2.419086e-05   \n",
       "TCGA.CN.4728.01A 0.0005285901    2.218801e-04    3.632771e-05   \n",
       "TCGA.CV.7090.01A 0.0003596658    1.054820e-04    2.264753e-05   \n",
       "TCGA.CV.5979.01A 0.0005035822    5.120770e-05    1.299737e-05   \n",
       "TCGA.CQ.7069.01A 0.0002819953    1.390721e-04    2.762522e-05   \n",
       "TCGA.CN.4733.01A 0.0012068362    5.583519e-04    6.333076e-04   \n",
       "TCGA.CR.7390.01A 0.0004419969    8.526116e-05    1.848770e-05   \n",
       "TCGA.CV.A45X.01A 0.0003150305    1.603280e-04    1.857990e-05   \n",
       "TCGA.IQ.A6SH.01A 0.0005290442    1.773073e-04    3.919241e-05   \n",
       "TCGA.CV.6962.11A 0.0003952625    1.381772e-04    5.441342e-05   \n",
       "TCGA.CV.6960.11A 0.0006173584    1.908321e-04    5.381925e-05   \n",
       "TCGA.CV.A464.01A 0.0005600828    2.327449e-04    2.054429e-05   \n",
       "TCGA.C9.A47Z.01A 0.0003100898    1.004789e-04    1.261151e-05   \n",
       "TCGA.CN.6010.01A 0.0012088467    2.459090e-04    2.192413e-04   \n",
       "TCGA.WA.A7GZ.11A 0.0005148579    2.727584e-04    3.413857e-05   \n",
       "TCGA.CV.7235.01A 0.0002247817    8.398276e-05    3.821899e-05   \n",
       "TCGA.CX.7086.01A 0.0007694788    1.362761e-04    7.474478e-05   \n",
       "TCGA.CV.6935.11A 0.0004130733    2.043172e-04    8.868809e-05   \n",
       "TCGA.P3.A6SW.01A 0.0020177067    5.459469e-04    2.847305e-04   \n",
       "TCGA.HD.A6HZ.01A 0.0007267136    1.949370e-04    1.929092e-04   \n",
       "                 ENSG00000254709 ENSG00000173486 ENSG00000213140\n",
       "TCGA.BB.4224.01A 3.616179e-06    0.0003700216    1.628714e-07   \n",
       "TCGA.H7.7774.01A 9.902832e-05    0.0002230157    1.000000e-08   \n",
       "TCGA.CV.6943.01A 4.693725e-04    0.0002469867    1.000000e-08   \n",
       "TCGA.CN.5374.01A 3.181145e-04    0.0005197946    1.000000e-08   \n",
       "TCGA.CQ.6227.01A 1.234068e-05    0.0005737245    1.000000e-08   \n",
       "TCGA.CV.6959.01A 1.818100e-04    0.0002814092    1.000000e-08   \n",
       "TCGA.F7.A61V.01A 8.356970e-05    0.0006785771    1.000000e-08   \n",
       "TCGA.CV.7413.01A 2.682257e-05    0.0003967018    1.000000e-08   \n",
       "TCGA.CV.7247.01A 2.104127e-06    0.0002724595    1.000000e-08   \n",
       "TCGA.CR.5249.01A 3.166782e-04    0.0002964787    1.000000e-08   \n",
       "TCGA.CQ.5331.01A 1.017654e-04    0.0002813868    1.000000e-08   \n",
       "TCGA.BB.8601.01A 4.327599e-04    0.0004442685    1.000000e-08   \n",
       "TCGA.CV.A45W.01A 6.717086e-04    0.0008967767    1.000000e-08   \n",
       "TCGA.CQ.7063.01A 6.918289e-06    0.0002003570    1.000000e-08   \n",
       "TCGA.CN.5373.01A 3.333021e-05    0.0002322776    1.000000e-08   \n",
       "TCGA.CV.A45T.01A 3.268788e-04    0.0004819631    1.000000e-08   \n",
       "TCGA.HD.A4C1.01A 1.552979e-04    0.0002556994    1.000000e-08   \n",
       "TCGA.CV.7438.11A 3.473233e-04    0.0002890306    1.000000e-08   \n",
       "TCGA.CV.5444.01A 2.521237e-05    0.0004050447    1.000000e-08   \n",
       "TCGA.BA.5556.01A 2.494859e-04    0.0002640489    1.000000e-08   \n",
       "TCGA.P3.A6SX.01A 4.604509e-06    0.0008899720    1.000000e-08   \n",
       "TCGA.CV.7242.11A 4.136964e-05    0.0003709810    1.000000e-08   \n",
       "TCGA.DQ.7592.01A 2.142013e-05    0.0002584084    5.705522e-08   \n",
       "TCGA.CV.6937.01A 8.759695e-06    0.0003191809    1.000000e-08   \n",
       "TCGA.QK.A8ZB.01A 6.930245e-04    0.0005834410    1.000000e-08   \n",
       "TCGA.CV.7432.01A 1.400034e-06    0.0005102209    1.000000e-08   \n",
       "TCGA.CV.7089.01A 2.554719e-05    0.0002767261    1.000000e-08   \n",
       "TCGA.CV.6939.11A 1.000000e-08    0.0003441230    1.000000e-08   \n",
       "TCGA.BA.4075.01A 4.625084e-06    0.0002565718    1.000000e-08   \n",
       "TCGA.T3.A92M.01A 4.426472e-04    0.0004964614    1.000000e-08   \n",
       "⋮                ⋮               ⋮               ⋮              \n",
       "TCGA.CV.7430.01A 2.524718e-05    0.0002446748    1.000000e-08   \n",
       "TCGA.D6.A74Q.01A 5.210625e-04    0.0006809090    1.000000e-08   \n",
       "TCGA.CV.7255.01A 2.235211e-05    0.0005886989    1.000000e-08   \n",
       "TCGA.CQ.6223.01A 1.756797e-04    0.0002270226    1.000000e-08   \n",
       "TCGA.CV.A460.01A 4.979068e-04    0.0005998793    1.000000e-08   \n",
       "TCGA.CV.7261.01A 4.453275e-04    0.0002607408    1.000000e-08   \n",
       "TCGA.CN.4736.01A 1.596004e-05    0.0004530299    1.000000e-08   \n",
       "TCGA.CR.7404.01A 4.117645e-04    0.0004241875    1.000000e-08   \n",
       "TCGA.UF.A719.01A 1.057499e-04    0.0006982935    1.265862e-07   \n",
       "TCGA.CV.7236.01A 3.696085e-05    0.0002600968    1.000000e-08   \n",
       "TCGA.CV.6951.01A 1.306260e-05    0.0005985506    1.000000e-08   \n",
       "TCGA.CN.4728.01A 8.188667e-05    0.0002971218    1.000000e-08   \n",
       "TCGA.CV.7090.01A 9.385449e-06    0.0003380583    1.000000e-08   \n",
       "TCGA.CV.5979.01A 4.211574e-06    0.0003494897    8.458415e-08   \n",
       "TCGA.CQ.7069.01A 4.101573e-06    0.0004693662    1.000000e-08   \n",
       "TCGA.CN.4733.01A 2.022035e-04    0.0004555842    1.000000e-08   \n",
       "TCGA.CR.7390.01A 2.279696e-05    0.0002935566    1.000000e-08   \n",
       "TCGA.CV.A45X.01A 2.948244e-05    0.0003965018    1.000000e-08   \n",
       "TCGA.IQ.A6SH.01A 2.574518e-04    0.0010084499    1.000000e-08   \n",
       "TCGA.CV.6962.11A 1.668698e-04    0.0002953859    1.000000e-08   \n",
       "TCGA.CV.6960.11A 1.531101e-05    0.0002441374    1.000000e-08   \n",
       "TCGA.CV.A464.01A 1.001617e-05    0.0004629118    1.000000e-08   \n",
       "TCGA.C9.A47Z.01A 1.596038e-05    0.0002968109    1.000000e-08   \n",
       "TCGA.CN.6010.01A 2.586062e-04    0.0003568362    1.624118e-08   \n",
       "TCGA.WA.A7GZ.11A 1.995681e-07    0.0002593855    1.000000e-08   \n",
       "TCGA.CV.7235.01A 5.479168e-06    0.0003393481    1.000000e-08   \n",
       "TCGA.CX.7086.01A 2.588934e-04    0.0002799019    1.000000e-08   \n",
       "TCGA.CV.6935.11A 7.729184e-05    0.0002672378    1.000000e-08   \n",
       "TCGA.P3.A6SW.01A 3.736049e-04    0.0007576098    1.000000e-08   \n",
       "TCGA.HD.A6HZ.01A 5.411360e-04    0.0002785809    1.000000e-08   \n",
       "                 ENSG00000100219 ⋯ ENSG00000197747 ENSG00000182004\n",
       "TCGA.BB.4224.01A 1e-08           ⋯ 0.002737765     5.773484e-04   \n",
       "TCGA.H7.7774.01A 1e-08           ⋯ 0.003337577     1.433087e-04   \n",
       "TCGA.CV.6943.01A 1e-08           ⋯ 0.003357789     1.559257e-04   \n",
       "TCGA.CN.5374.01A 1e-08           ⋯ 0.010330342     4.239480e-04   \n",
       "TCGA.CQ.6227.01A 1e-08           ⋯ 0.004530666     2.386463e-04   \n",
       "TCGA.CV.6959.01A 1e-08           ⋯ 0.004082648     2.200997e-04   \n",
       "TCGA.F7.A61V.01A 1e-08           ⋯ 0.005626857     4.308986e-04   \n",
       "TCGA.CV.7413.01A 1e-08           ⋯ 0.004879131     2.800998e-04   \n",
       "TCGA.CV.7247.01A 1e-08           ⋯ 0.005585513     3.754058e-04   \n",
       "TCGA.CR.5249.01A 1e-08           ⋯ 0.002960998     1.687711e-04   \n",
       "TCGA.CQ.5331.01A 1e-08           ⋯ 0.002116966     2.158482e-04   \n",
       "TCGA.BB.8601.01A 1e-08           ⋯ 0.005941892     7.148520e-04   \n",
       "TCGA.CV.A45W.01A 1e-08           ⋯ 0.001917906     3.920446e-04   \n",
       "TCGA.CQ.7063.01A 1e-08           ⋯ 0.003398543     1.586570e-04   \n",
       "TCGA.CN.5373.01A 1e-08           ⋯ 0.001655155     8.016141e-05   \n",
       "TCGA.CV.A45T.01A 1e-08           ⋯ 0.004611893     3.322539e-04   \n",
       "TCGA.HD.A4C1.01A 1e-08           ⋯ 0.004476140     2.377950e-04   \n",
       "TCGA.CV.7438.11A 1e-08           ⋯ 0.004479447     2.357138e-04   \n",
       "TCGA.CV.5444.01A 1e-08           ⋯ 0.003810114     2.579929e-04   \n",
       "TCGA.BA.5556.01A 1e-08           ⋯ 0.003600573     1.634347e-04   \n",
       "TCGA.P3.A6SX.01A 1e-08           ⋯ 0.006280771     5.346874e-04   \n",
       "TCGA.CV.7242.11A 1e-08           ⋯ 0.007369572     3.025168e-04   \n",
       "TCGA.DQ.7592.01A 1e-08           ⋯ 0.003336019     2.514070e-04   \n",
       "TCGA.CV.6937.01A 1e-08           ⋯ 0.004346442     5.132510e-04   \n",
       "TCGA.QK.A8ZB.01A 1e-08           ⋯ 0.002897496     2.532544e-04   \n",
       "TCGA.CV.7432.01A 1e-08           ⋯ 0.006701766     3.634160e-04   \n",
       "TCGA.CV.7089.01A 1e-08           ⋯ 0.007622057     2.258614e-04   \n",
       "TCGA.CV.6939.11A 1e-08           ⋯ 0.000344123     1.032349e-03   \n",
       "TCGA.BA.4075.01A 1e-08           ⋯ 0.008498127     6.507726e-04   \n",
       "TCGA.T3.A92M.01A 1e-08           ⋯ 0.004055301     6.537091e-04   \n",
       "⋮                ⋮               ⋱ ⋮               ⋮              \n",
       "TCGA.CV.7430.01A 1e-08           ⋯ 0.007121540     0.0002895846   \n",
       "TCGA.D6.A74Q.01A 1e-08           ⋯ 0.005756178     0.0006227999   \n",
       "TCGA.CV.7255.01A 1e-08           ⋯ 0.005428264     0.0002686081   \n",
       "TCGA.CQ.6223.01A 1e-08           ⋯ 0.003053088     0.0001634606   \n",
       "TCGA.CV.A460.01A 1e-08           ⋯ 0.003110662     0.0004130311   \n",
       "TCGA.CV.7261.01A 1e-08           ⋯ 0.003258928     0.0004946441   \n",
       "TCGA.CN.4736.01A 1e-08           ⋯ 0.002296859     0.0001688855   \n",
       "TCGA.CR.7404.01A 1e-08           ⋯ 0.003802623     0.0003162880   \n",
       "TCGA.UF.A719.01A 1e-08           ⋯ 0.003819092     0.0005531189   \n",
       "TCGA.CV.7236.01A 1e-08           ⋯ 0.006065872     0.0002268857   \n",
       "TCGA.CV.6951.01A 1e-08           ⋯ 0.003143431     0.0003646987   \n",
       "TCGA.CN.4728.01A 1e-08           ⋯ 0.004889457     0.0002230085   \n",
       "TCGA.CV.7090.01A 1e-08           ⋯ 0.003985342     0.0001846142   \n",
       "TCGA.CV.5979.01A 1e-08           ⋯ 0.009375253     0.0002882151   \n",
       "TCGA.CQ.7069.01A 1e-08           ⋯ 0.005293376     0.0001213396   \n",
       "TCGA.CN.4733.01A 1e-08           ⋯ 0.002585773     0.0002927561   \n",
       "TCGA.CR.7390.01A 1e-08           ⋯ 0.003986079     0.0002778338   \n",
       "TCGA.CV.A45X.01A 1e-08           ⋯ 0.005119607     0.0002482347   \n",
       "TCGA.IQ.A6SH.01A 1e-08           ⋯ 0.006610426     0.0004966262   \n",
       "TCGA.CV.6962.11A 1e-08           ⋯ 0.006503971     0.0001457363   \n",
       "TCGA.CV.6960.11A 1e-08           ⋯ 0.006409453     0.0002095843   \n",
       "TCGA.CV.A464.01A 1e-08           ⋯ 0.004771309     0.0003365614   \n",
       "TCGA.C9.A47Z.01A 1e-08           ⋯ 0.002239680     0.0001309478   \n",
       "TCGA.CN.6010.01A 1e-08           ⋯ 0.003840012     0.0004233957   \n",
       "TCGA.WA.A7GZ.11A 1e-08           ⋯ 0.003282486     0.0002161534   \n",
       "TCGA.CV.7235.01A 1e-08           ⋯ 0.004799518     0.0002369377   \n",
       "TCGA.CX.7086.01A 1e-08           ⋯ 0.002860567     0.0002871156   \n",
       "TCGA.CV.6935.11A 1e-08           ⋯ 0.004900983     0.0001527211   \n",
       "TCGA.P3.A6SW.01A 1e-08           ⋯ 0.005294263     0.0008564356   \n",
       "TCGA.HD.A6HZ.01A 1e-08           ⋯ 0.006158281     0.0003242550   \n",
       "                 ENSG00000166145 ENSG00000121552 ENSG00000139324\n",
       "TCGA.BB.4224.01A 0.0017739162    0.0089543412    0.0008018141   \n",
       "TCGA.H7.7774.01A 0.0014243026    0.0166559084    0.0005140027   \n",
       "TCGA.CV.6943.01A 0.0038717172    0.0024351945    0.0004150751   \n",
       "TCGA.CN.5374.01A 0.0050937505    0.0026178135    0.0003574237   \n",
       "TCGA.CQ.6227.01A 0.0017714377    0.0053466289    0.0005887246   \n",
       "TCGA.CV.6959.01A 0.0013295819    0.0023046395    0.0004808925   \n",
       "TCGA.F7.A61V.01A 0.0022317165    0.0323772297    0.0004708252   \n",
       "TCGA.CV.7413.01A 0.0037563555    0.0017821653    0.0005171505   \n",
       "TCGA.CV.7247.01A 0.0020373186    0.0029178676    0.0009947036   \n",
       "TCGA.CR.5249.01A 0.0031681877    0.0034204397    0.0010516075   \n",
       "TCGA.CQ.5331.01A 0.0008185703    0.0104473836    0.0004349681   \n",
       "TCGA.BB.8601.01A 0.0013883150    0.0072199093    0.0012015445   \n",
       "TCGA.CV.A45W.01A 0.0019031008    0.0051938047    0.0007790055   \n",
       "TCGA.CQ.7063.01A 0.0017012382    0.0032522460    0.0003016946   \n",
       "TCGA.CN.5373.01A 0.0016525510    0.0055143119    0.0005213437   \n",
       "TCGA.CV.A45T.01A 0.0011057098    0.0113060985    0.0002201174   \n",
       "TCGA.HD.A4C1.01A 0.0017209266    0.0049206500    0.0007088569   \n",
       "TCGA.CV.7438.11A 0.0018305646    0.0154356225    0.0002963051   \n",
       "TCGA.CV.5444.01A 0.0026027185    0.0020095220    0.0004906207   \n",
       "TCGA.BA.5556.01A 0.0018362387    0.0028587916    0.0003777037   \n",
       "TCGA.P3.A6SX.01A 0.0023197761    0.0022712824    0.0005605644   \n",
       "TCGA.CV.7242.11A 0.0032612093    0.0200354832    0.0002793075   \n",
       "TCGA.DQ.7592.01A 0.0032934795    0.0018629622    0.0005402061   \n",
       "TCGA.CV.6937.01A 0.0023996582    0.0009491521    0.0003516651   \n",
       "TCGA.QK.A8ZB.01A 0.0017825461    0.0130022214    0.0004766300   \n",
       "TCGA.CV.7432.01A 0.0007841787    0.0012932573    0.0005436148   \n",
       "TCGA.CV.7089.01A 0.0018506403    0.0101614970    0.0003772263   \n",
       "TCGA.CV.6939.11A 0.0223673555    0.0048175921    0.0003441230   \n",
       "TCGA.BA.4075.01A 0.0008981257    0.0017960672    0.0002748242   \n",
       "TCGA.T3.A92M.01A 0.0017117580    0.0015475192    0.0006276969   \n",
       "⋮                ⋮               ⋮               ⋮              \n",
       "TCGA.CV.7430.01A 0.0036654498    0.0048225068    0.0006275938   \n",
       "TCGA.D6.A74Q.01A 0.0019739963    0.0054332114    0.0006227270   \n",
       "TCGA.CV.7255.01A 0.0025571581    0.0021710324    0.0003400059   \n",
       "TCGA.CQ.6223.01A 0.0022289593    0.0077123084    0.0004166915   \n",
       "TCGA.CV.A460.01A 0.0023860029    0.0026728659    0.0006409095   \n",
       "TCGA.CV.7261.01A 0.0011090316    0.0016310078    0.0012178321   \n",
       "TCGA.CN.4736.01A 0.0031227601    0.0023390499    0.0008105389   \n",
       "TCGA.CR.7404.01A 0.0035471866    0.0058780413    0.0008346040   \n",
       "TCGA.UF.A719.01A 0.0034956357    0.0108619360    0.0004804429   \n",
       "TCGA.CV.7236.01A 0.0027198014    0.0005824110    0.0008134314   \n",
       "TCGA.CV.6951.01A 0.0025639218    0.0020115784    0.0012760151   \n",
       "TCGA.CN.4728.01A 0.0029011805    0.0052395438    0.0004271121   \n",
       "TCGA.CV.7090.01A 0.0017219079    0.0010546015    0.0005727302   \n",
       "TCGA.CV.5979.01A 0.0009895547    0.0014856896    0.0004415379   \n",
       "TCGA.CQ.7069.01A 0.0021885387    0.0015807052    0.0005381306   \n",
       "TCGA.CN.4733.01A 0.0011298140    0.0013298247    0.0004118300   \n",
       "TCGA.CR.7390.01A 0.0024745965    0.0032429093    0.0004728013   \n",
       "TCGA.CV.A45X.01A 0.0037442767    0.0094928233    0.0002827414   \n",
       "TCGA.IQ.A6SH.01A 0.0017259967    0.0029736185    0.0002355422   \n",
       "TCGA.CV.6962.11A 0.0051940113    0.0194390703    0.0002386599   \n",
       "TCGA.CV.6960.11A 0.0028872163    0.0110644614    0.0004092271   \n",
       "TCGA.CV.A464.01A 0.0021381656    0.0012481794    0.0006264352   \n",
       "TCGA.C9.A47Z.01A 0.0015309809    0.0059378962    0.0006212079   \n",
       "TCGA.CN.6010.01A 0.0021606340    0.0007145344    0.0015495287   \n",
       "TCGA.WA.A7GZ.11A 0.0053297142    0.0489133412    0.0004428642   \n",
       "TCGA.CV.7235.01A 0.0015920840    0.0001192039    0.0006553211   \n",
       "TCGA.CX.7086.01A 0.0020469296    0.0110965045    0.0004396349   \n",
       "TCGA.CV.6935.11A 0.0033053024    0.0186461451    0.0003531671   \n",
       "TCGA.P3.A6SW.01A 0.0038805225    0.0054065055    0.0005171346   \n",
       "TCGA.HD.A6HZ.01A 0.0018518827    0.0028840979    0.0009633043   \n",
       "                 ENSG00000139343 ENSG00000237945 ENSG00000264230\n",
       "TCGA.BB.4224.01A 6.692068e-04    2.308098e-04    4.367240e-04   \n",
       "TCGA.H7.7774.01A 3.059268e-04    5.841788e-05    3.626587e-04   \n",
       "TCGA.CV.6943.01A 1.871413e-04    1.157592e-04    5.567893e-04   \n",
       "TCGA.CN.5374.01A 5.400711e-04    2.654795e-05    3.842901e-04   \n",
       "TCGA.CQ.6227.01A 2.386188e-04    1.066649e-04    4.524921e-04   \n",
       "TCGA.CV.6959.01A 3.583344e-04    7.808572e-05    3.079049e-04   \n",
       "TCGA.F7.A61V.01A 5.992306e-04    1.352416e-05    2.127113e-04   \n",
       "TCGA.CV.7413.01A 3.428029e-04    1.394460e-04    3.722275e-04   \n",
       "TCGA.CV.7247.01A 4.143002e-04    1.677187e-04    5.068920e-04   \n",
       "TCGA.CR.5249.01A 1.980024e-04    1.816146e-04    5.952634e-04   \n",
       "TCGA.CQ.5331.01A 2.344521e-04    6.835260e-05    2.280540e-04   \n",
       "TCGA.BB.8601.01A 7.152516e-04    4.785123e-05    2.400354e-04   \n",
       "TCGA.CV.A45W.01A 5.906361e-04    8.620462e-05    6.646666e-05   \n",
       "TCGA.CQ.7063.01A 1.823135e-04    8.863041e-05    4.228896e-04   \n",
       "TCGA.CN.5373.01A 9.728658e-05    8.536740e-05    4.841650e-04   \n",
       "TCGA.CV.A45T.01A 3.553431e-04    5.015535e-05    4.797819e-04   \n",
       "TCGA.HD.A4C1.01A 2.931246e-04    7.256049e-05    3.215368e-04   \n",
       "TCGA.CV.7438.11A 3.234816e-04    7.462886e-05    4.099938e-04   \n",
       "TCGA.CV.5444.01A 3.024435e-04    1.801730e-04    7.470174e-04   \n",
       "TCGA.BA.5556.01A 2.260585e-04    1.605390e-04    4.405382e-04   \n",
       "TCGA.P3.A6SX.01A 5.489885e-04    6.276184e-05    1.764815e-04   \n",
       "TCGA.CV.7242.11A 4.638789e-04    5.193720e-05    2.945520e-04   \n",
       "TCGA.DQ.7592.01A 2.796855e-04    8.865398e-05    3.579947e-04   \n",
       "TCGA.CV.6937.01A 3.318331e-04    6.027308e-05    6.927646e-04   \n",
       "TCGA.QK.A8ZB.01A 3.081891e-04    1.585205e-04    7.080066e-04   \n",
       "TCGA.CV.7432.01A 3.844492e-04    8.900618e-05    5.164222e-04   \n",
       "TCGA.CV.7089.01A 3.286588e-04    6.041428e-05    4.450423e-04   \n",
       "TCGA.CV.6939.11A 3.441230e-04    1.000000e-08    1.000000e-08   \n",
       "TCGA.BA.4075.01A 3.098169e-04    9.336014e-05    5.669379e-04   \n",
       "TCGA.T3.A92M.01A 1.026578e-03    9.259499e-05    3.069821e-04   \n",
       "⋮                ⋮               ⋮               ⋮              \n",
       "TCGA.CV.7430.01A 0.0003736934    4.550609e-05    0.0005383872   \n",
       "TCGA.D6.A74Q.01A 0.0007671214    7.493450e-05    0.0004953226   \n",
       "TCGA.CV.7255.01A 0.0001293436    1.606496e-04    0.0006389083   \n",
       "TCGA.CQ.6223.01A 0.0002387974    4.522391e-05    0.0002499937   \n",
       "TCGA.CV.A460.01A 0.0006411616    9.773172e-05    0.0002105587   \n",
       "TCGA.CV.7261.01A 0.0004925674    6.676863e-05    0.0001493141   \n",
       "TCGA.CN.4736.01A 0.0001891924    1.701151e-04    0.0009726216   \n",
       "TCGA.CR.7404.01A 0.0004172660    3.501289e-04    0.0001747886   \n",
       "TCGA.UF.A719.01A 0.0004463037    1.825883e-04    0.0002105398   \n",
       "TCGA.CV.7236.01A 0.0002646659    1.159172e-04    0.0008765738   \n",
       "TCGA.CV.6951.01A 0.0003109368    9.188377e-05    0.0002664351   \n",
       "TCGA.CN.4728.01A 0.0002519848    1.238790e-04    0.0006565699   \n",
       "TCGA.CV.7090.01A 0.0002025254    5.760173e-05    0.0002389454   \n",
       "TCGA.CV.5979.01A 0.0002778468    3.733991e-05    0.0005769098   \n",
       "TCGA.CQ.7069.01A 0.0001384772    2.787824e-05    0.0002499133   \n",
       "TCGA.CN.4733.01A 0.0003140261    1.196029e-04    0.0003824203   \n",
       "TCGA.CR.7390.01A 0.0001709763    4.543200e-05    0.0003704545   \n",
       "TCGA.CV.A45X.01A 0.0002545380    7.346472e-05    0.0002453223   \n",
       "TCGA.IQ.A6SH.01A 0.0004633796    8.418996e-05    0.0003543382   \n",
       "TCGA.CV.6962.11A 0.0001966075    1.001317e-04    0.0004664489   \n",
       "TCGA.CV.6960.11A 0.0002899279    7.510687e-05    0.0002899852   \n",
       "TCGA.CV.A464.01A 0.0004487420    7.497420e-05    0.0005972093   \n",
       "TCGA.C9.A47Z.01A 0.0001875071    7.887333e-05    0.0005531027   \n",
       "TCGA.CN.6010.01A 0.0005200101    8.844130e-05    0.0002229744   \n",
       "TCGA.WA.A7GZ.11A 0.0002246060    4.091036e-05    0.0007222012   \n",
       "TCGA.CV.7235.01A 0.0002931653    6.543051e-05    0.0002908468   \n",
       "TCGA.CX.7086.01A 0.0003355767    3.549545e-05    0.0002100881   \n",
       "TCGA.CV.6935.11A 0.0002227639    5.020764e-05    0.0002912144   \n",
       "TCGA.P3.A6SW.01A 0.0009597469    1.195716e-04    0.0003468781   \n",
       "TCGA.HD.A6HZ.01A 0.0003997828    1.216862e-04    0.0003307637   \n",
       "                 ENSG00000185479 ENSG00000196262\n",
       "TCGA.BB.4224.01A 0.009079472     0.013460871    \n",
       "TCGA.H7.7774.01A 0.084561644     0.002045631    \n",
       "TCGA.CV.6943.01A 0.054130245     0.001652089    \n",
       "TCGA.CN.5374.01A 0.002485788     0.002593591    \n",
       "TCGA.CQ.6227.01A 0.030182147     0.002398836    \n",
       "TCGA.CV.6959.01A 0.029175120     0.002409821    \n",
       "TCGA.F7.A61V.01A 0.032960660     0.004283686    \n",
       "TCGA.CV.7413.01A 0.038769554     0.002416373    \n",
       "TCGA.CV.7247.01A 0.021828081     0.004925209    \n",
       "TCGA.CR.5249.01A 0.011545750     0.002209561    \n",
       "TCGA.CQ.5331.01A 0.073982929     0.002414117    \n",
       "TCGA.BB.8601.01A 0.018089630     0.006423278    \n",
       "TCGA.CV.A45W.01A 0.002525816     0.003339710    \n",
       "TCGA.CQ.7063.01A 0.047377067     0.002186628    \n",
       "TCGA.CN.5373.01A 0.110119547     0.001424400    \n",
       "TCGA.CV.A45T.01A 0.073378459     0.003104214    \n",
       "TCGA.HD.A4C1.01A 0.041926520     0.002846415    \n",
       "TCGA.CV.7438.11A 0.036995445     0.002871761    \n",
       "TCGA.CV.5444.01A 0.020614277     0.002462434    \n",
       "TCGA.BA.5556.01A 0.032918689     0.002362555    \n",
       "TCGA.P3.A6SX.01A 0.036640466     0.004356166    \n",
       "TCGA.CV.7242.11A 0.002345791     0.003399956    \n",
       "TCGA.DQ.7592.01A 0.009928997     0.003024097    \n",
       "TCGA.CV.6937.01A 0.004763760     0.003762372    \n",
       "TCGA.QK.A8ZB.01A 0.034975994     0.002742837    \n",
       "TCGA.CV.7432.01A 0.020327529     0.004136221    \n",
       "TCGA.CV.7089.01A 0.028509745     0.002970316    \n",
       "TCGA.CV.6939.11A 0.000344123     0.000344123    \n",
       "TCGA.BA.4075.01A 0.004266577     0.012449356    \n",
       "TCGA.T3.A92M.01A 0.007744020     0.003446403    \n",
       "⋮                ⋮               ⋮              \n",
       "TCGA.CV.7430.01A 0.0145368126    0.001343983    \n",
       "TCGA.D6.A74Q.01A 0.0095378436    0.005052232    \n",
       "TCGA.CV.7255.01A 0.0108127902    0.003692008    \n",
       "TCGA.CQ.6223.01A 0.0602492184    0.002551418    \n",
       "TCGA.CV.A460.01A 0.0038085032    0.004627804    \n",
       "TCGA.CV.7261.01A 0.0172405230    0.002004587    \n",
       "TCGA.CN.4736.01A 0.0386288860    0.001846247    \n",
       "TCGA.CR.7404.01A 0.0043973878    0.002804166    \n",
       "TCGA.UF.A719.01A 0.0061043322    0.002410001    \n",
       "TCGA.CV.7236.01A 0.0277032892    0.003632712    \n",
       "TCGA.CV.6951.01A 0.0191011166    0.003565509    \n",
       "TCGA.CN.4728.01A 0.0325675873    0.002063437    \n",
       "TCGA.CV.7090.01A 0.0243289623    0.002574986    \n",
       "TCGA.CV.5979.01A 0.0267583905    0.002554498    \n",
       "TCGA.CQ.7069.01A 0.0364606068    0.002397554    \n",
       "TCGA.CN.4733.01A 0.0179908098    0.002058683    \n",
       "TCGA.CR.7390.01A 0.0225988761    0.002880202    \n",
       "TCGA.CV.A45X.01A 0.0181047634    0.005153022    \n",
       "TCGA.IQ.A6SH.01A 0.0480659416    0.004541411    \n",
       "TCGA.CV.6962.11A 0.0064596702    0.002182135    \n",
       "TCGA.CV.6960.11A 0.0061605791    0.002550240    \n",
       "TCGA.CV.A464.01A 0.0293922083    0.002852930    \n",
       "TCGA.C9.A47Z.01A 0.0992483984    0.002564241    \n",
       "TCGA.CN.6010.01A 0.0082722783    0.002362312    \n",
       "TCGA.WA.A7GZ.11A 0.0020397140    0.001236956    \n",
       "TCGA.CV.7235.01A 0.0007669689    0.003346472    \n",
       "TCGA.CX.7086.01A 0.0338536139    0.003258462    \n",
       "TCGA.CV.6935.11A 0.0094543972    0.002323451    \n",
       "TCGA.P3.A6SW.01A 0.0036510506    0.006277217    \n",
       "TCGA.HD.A6HZ.01A 0.0263178340    0.002522418    "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "# the normalized expression of malignant cells inferred by the \n",
    "# deconvolution module of BayesPrism\n",
    "res$res$first.gibbs.res$Zkg.tum.norm"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 1,
   "id": "a355b99a",
   "metadata": {},
   "outputs": [],
   "source": [
    "# results with subtypes info provided\n",
    "res1 <- readRDS(\"/home/cke/BayesPrism/BP_PuramTCGA_res_withSubtypes.rds\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 2,
   "id": "b4bd6fc0",
   "metadata": {
    "collapsed": true
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<table class=\"dataframe\">\n",
       "<caption>A matrix: 546 × 10 of type dbl</caption>\n",
       "<thead>\n",
       "\t<tr><th></th><th scope=col>tumor</th><th scope=col>Fibroblast</th><th scope=col>B cell</th><th scope=col>myocyte</th><th scope=col></th><th scope=col>Macrophage</th><th scope=col>Endothelial</th><th scope=col>T cell</th><th scope=col>Dendritic</th><th scope=col>Mast</th></tr>\n",
       "</thead>\n",
       "<tbody>\n",
       "\t<tr><th scope=row>TCGA.BB.4224.01A</th><td>0.98038950</td><td>2.594618e-03</td><td>3.542329e-07</td><td>2.766217e-03</td><td>3.499656e-07</td><td>3.205483e-03</td><td>0.0027510827</td><td>8.521628e-04</td><td>1.016656e-03</td><td>6.423578e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.H7.7774.01A</th><td>0.97999996</td><td>6.149258e-06</td><td>1.185681e-04</td><td>6.914936e-06</td><td>5.846047e-07</td><td>1.016967e-02</td><td>0.0035357181</td><td>4.121756e-03</td><td>4.625486e-04</td><td>1.578125e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6943.01A</th><td>0.56646958</td><td>3.493160e-01</td><td>1.944879e-03</td><td>4.905889e-06</td><td>1.315783e-07</td><td>4.707874e-02</td><td>0.0161258815</td><td>1.839627e-02</td><td>3.755185e-07</td><td>6.632165e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.5374.01A</th><td>0.88892935</td><td>1.747085e-02</td><td>6.275153e-03</td><td>6.242288e-03</td><td>2.276322e-04</td><td>9.439050e-03</td><td>0.0200368767</td><td>3.626590e-02</td><td>1.486504e-02</td><td>2.478594e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.6227.01A</th><td>0.68066452</td><td>2.067763e-01</td><td>3.081748e-07</td><td>7.023912e-02</td><td>1.821531e-07</td><td>5.534975e-03</td><td>0.0367537905</td><td>1.512429e-06</td><td>4.965544e-07</td><td>2.884320e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6959.01A</th><td>0.80997894</td><td>6.934166e-02</td><td>1.838830e-04</td><td>6.348739e-02</td><td>2.532585e-07</td><td>1.998996e-02</td><td>0.0345198484</td><td>2.438478e-03</td><td>9.642066e-06</td><td>4.995040e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.F7.A61V.01A</th><td>0.92712831</td><td>1.167329e-02</td><td>1.405441e-03</td><td>2.250048e-02</td><td>2.605740e-02</td><td>1.886437e-03</td><td>0.0066788937</td><td>2.590494e-03</td><td>7.817416e-05</td><td>1.084985e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7413.01A</th><td>0.79351483</td><td>1.899651e-01</td><td>2.497154e-07</td><td>7.611108e-08</td><td>1.516735e-07</td><td>1.509406e-02</td><td>0.0002650205</td><td>1.158590e-03</td><td>6.951192e-07</td><td>1.209006e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7247.01A</th><td>0.81193494</td><td>8.785088e-02</td><td>2.399171e-07</td><td>7.770501e-02</td><td>1.929737e-07</td><td>4.909193e-07</td><td>0.0225072633</td><td>3.055039e-07</td><td>3.806278e-07</td><td>2.979071e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CR.5249.01A</th><td>0.84617612</td><td>4.345764e-02</td><td>7.878960e-03</td><td>1.676177e-07</td><td>2.584262e-05</td><td>1.372778e-02</td><td>0.0294192277</td><td>3.773021e-02</td><td>2.083079e-02</td><td>7.532636e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.5331.01A</th><td>0.88723094</td><td>3.027107e-02</td><td>4.500219e-04</td><td>9.825687e-08</td><td>1.526343e-07</td><td>4.094953e-02</td><td>0.0282584633</td><td>1.282334e-02</td><td>2.264620e-06</td><td>1.412457e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.BB.8601.01A</th><td>0.99449058</td><td>3.004478e-03</td><td>2.596958e-04</td><td>4.064385e-07</td><td>1.139609e-06</td><td>5.701152e-06</td><td>0.0017967220</td><td>6.800982e-06</td><td>7.853000e-06</td><td>4.266186e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A45W.01A</th><td>0.75468855</td><td>8.971029e-02</td><td>4.620753e-02</td><td>2.030031e-07</td><td>1.621886e-06</td><td>5.955070e-02</td><td>0.0389652427</td><td>8.388750e-03</td><td>2.356948e-03</td><td>1.301651e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.7063.01A</th><td>0.92415516</td><td>1.118447e-02</td><td>2.787730e-07</td><td>4.573217e-07</td><td>3.122681e-07</td><td>3.636450e-02</td><td>0.0128010647</td><td>1.412812e-02</td><td>7.407397e-06</td><td>1.358236e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.5373.01A</th><td>0.80822906</td><td>1.620342e-01</td><td>3.659689e-07</td><td>1.001210e-03</td><td>2.087811e-07</td><td>1.602183e-02</td><td>0.0070769511</td><td>4.569774e-03</td><td>9.695640e-07</td><td>1.065404e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A45T.01A</th><td>0.82338761</td><td>5.750264e-02</td><td>6.487877e-03</td><td>1.520020e-02</td><td>2.648398e-07</td><td>4.036712e-02</td><td>0.0227938419</td><td>2.991178e-02</td><td>2.936400e-03</td><td>1.412267e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.HD.A4C1.01A</th><td>0.90505535</td><td>7.572432e-02</td><td>5.779359e-07</td><td>1.074455e-07</td><td>1.710072e-07</td><td>1.424286e-03</td><td>0.0163282379</td><td>1.465662e-03</td><td>5.303616e-07</td><td>7.569981e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7438.11A</th><td>0.93638368</td><td>8.368108e-03</td><td>1.999069e-03</td><td>3.613508e-03</td><td>1.370744e-02</td><td>5.852535e-03</td><td>0.0107569622</td><td>1.061688e-02</td><td>6.783799e-03</td><td>1.918018e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.5444.01A</th><td>0.45781938</td><td>4.530313e-01</td><td>1.842252e-07</td><td>3.656274e-02</td><td>2.025264e-07</td><td>4.256179e-02</td><td>0.0099645520</td><td>5.893161e-05</td><td>5.154288e-07</td><td>4.115048e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.BA.5556.01A</th><td>0.87839845</td><td>3.728688e-02</td><td>9.524298e-05</td><td>1.101190e-07</td><td>3.507002e-07</td><td>3.033017e-02</td><td>0.0256290186</td><td>2.734716e-02</td><td>3.962926e-04</td><td>5.163185e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.P3.A6SX.01A</th><td>0.91814480</td><td>6.587246e-02</td><td>2.774646e-07</td><td>1.157012e-02</td><td>1.856887e-07</td><td>3.212785e-07</td><td>0.0044105862</td><td>2.746228e-07</td><td>3.273847e-07</td><td>6.389206e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7242.11A</th><td>0.93168231</td><td>9.486023e-03</td><td>3.085642e-04</td><td>6.096573e-06</td><td>2.451504e-02</td><td>6.718584e-03</td><td>0.0178043874</td><td>5.060592e-03</td><td>3.867446e-03</td><td>5.509531e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.DQ.7592.01A</th><td>0.86345804</td><td>1.032917e-01</td><td>2.761607e-07</td><td>1.382413e-02</td><td>1.791237e-07</td><td>6.317502e-03</td><td>0.0090219893</td><td>4.071058e-03</td><td>1.099434e-06</td><td>1.407329e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6937.01A</th><td>0.86132265</td><td>1.245604e-01</td><td>2.852322e-07</td><td>3.081682e-04</td><td>4.121824e-07</td><td>9.838171e-03</td><td>0.0031514595</td><td>7.525971e-04</td><td>7.162633e-06</td><td>5.867516e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.QK.A8ZB.01A</th><td>0.86047924</td><td>1.138247e-01</td><td>6.991782e-03</td><td>7.837195e-08</td><td>6.567427e-07</td><td>4.419482e-03</td><td>0.0131111392</td><td>1.811812e-04</td><td>5.960970e-06</td><td>9.858184e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7432.01A</th><td>0.97786072</td><td>1.316335e-02</td><td>2.535737e-07</td><td>1.940134e-07</td><td>1.956811e-07</td><td>2.062597e-03</td><td>0.0068747131</td><td>1.695925e-06</td><td>1.465643e-06</td><td>3.481186e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7089.01A</th><td>0.95819751</td><td>8.616876e-03</td><td>3.563113e-07</td><td>1.938822e-07</td><td>2.799753e-07</td><td>4.091022e-03</td><td>0.0247870361</td><td>3.401242e-03</td><td>4.093320e-05</td><td>8.645486e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6939.11A</th><td>0.04752636</td><td>1.577154e-02</td><td>1.029359e-07</td><td>5.747453e-01</td><td>3.565640e-01</td><td>1.978836e-07</td><td>0.0053921310</td><td>1.012707e-07</td><td>1.102215e-07</td><td>8.236693e-08</td></tr>\n",
       "\t<tr><th scope=row>TCGA.BA.4075.01A</th><td>0.92729488</td><td>3.900997e-02</td><td>2.596525e-07</td><td>2.943743e-03</td><td>2.705945e-07</td><td>2.353454e-02</td><td>0.0072138009</td><td>7.356434e-07</td><td>8.249225e-07</td><td>9.784210e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.T3.A92M.01A</th><td>0.70669416</td><td>2.534978e-01</td><td>1.801154e-03</td><td>1.151203e-07</td><td>2.115310e-07</td><td>2.353283e-02</td><td>0.0051027846</td><td>9.364755e-03</td><td>4.379953e-06</td><td>1.827037e-06</td></tr>\n",
       "\t<tr><th scope=row>⋮</th><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7430.01A</th><td>0.9775556</td><td>0.012994738</td><td>3.468448e-07</td><td>3.481714e-07</td><td>2.987451e-07</td><td>7.406797e-06</td><td>0.0089285027</td><td>3.719067e-04</td><td>1.150469e-06</td><td>1.397407e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.D6.A74Q.01A</th><td>0.8951440</td><td>0.073186538</td><td>5.733125e-03</td><td>1.678243e-07</td><td>1.929869e-06</td><td>4.427085e-03</td><td>0.0109295967</td><td>7.628079e-03</td><td>4.126484e-06</td><td>2.945363e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7255.01A</th><td>0.9585207</td><td>0.016602113</td><td>2.803171e-07</td><td>9.117775e-03</td><td>1.327139e-06</td><td>8.142290e-07</td><td>0.0157469068</td><td>2.773065e-06</td><td>6.830472e-07</td><td>6.657474e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.6223.01A</th><td>0.9785777</td><td>0.006376907</td><td>3.504493e-04</td><td>1.136500e-07</td><td>2.677071e-07</td><td>6.669418e-03</td><td>0.0036268131</td><td>2.983661e-03</td><td>9.399514e-06</td><td>1.405228e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A460.01A</th><td>0.7679894</td><td>0.129785718</td><td>2.010091e-03</td><td>1.320870e-07</td><td>3.445873e-07</td><td>2.668422e-02</td><td>0.0292931786</td><td>1.162323e-02</td><td>3.257454e-02</td><td>3.913460e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7261.01A</th><td>0.7713323</td><td>0.186662086</td><td>1.556092e-03</td><td>1.611414e-07</td><td>1.738965e-02</td><td>1.025543e-02</td><td>0.0124651460</td><td>1.432732e-04</td><td>1.109496e-05</td><td>1.847530e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.4736.01A</th><td>0.6304820</td><td>0.174913686</td><td>3.079871e-07</td><td>1.060600e-01</td><td>1.372099e-07</td><td>6.255270e-02</td><td>0.0181550094</td><td>7.823595e-03</td><td>1.984714e-06</td><td>1.052495e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CR.7404.01A</th><td>0.8533313</td><td>0.041698074</td><td>5.792933e-03</td><td>1.907846e-07</td><td>1.271039e-05</td><td>3.034583e-02</td><td>0.0380688750</td><td>2.377546e-02</td><td>6.829564e-03</td><td>1.450703e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.UF.A719.01A</th><td>0.9690552</td><td>0.012148216</td><td>7.850680e-05</td><td>2.362336e-05</td><td>1.100021e-06</td><td>3.806986e-03</td><td>0.0124009164</td><td>2.460801e-03</td><td>1.069183e-05</td><td>1.396653e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7236.01A</th><td>0.8157329</td><td>0.153543909</td><td>6.882169e-07</td><td>8.274678e-08</td><td>5.506422e-07</td><td>4.877831e-03</td><td>0.0249209884</td><td>9.160930e-04</td><td>5.913151e-06</td><td>1.046194e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6951.01A</th><td>0.9042730</td><td>0.044296484</td><td>2.524641e-07</td><td>2.115219e-02</td><td>2.859531e-02</td><td>8.234009e-06</td><td>0.0005141088</td><td>2.624854e-04</td><td>8.164200e-07</td><td>8.971539e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.4728.01A</th><td>0.3117590</td><td>0.583960572</td><td>1.911424e-07</td><td>5.530369e-03</td><td>1.610631e-07</td><td>8.658337e-02</td><td>0.0121642672</td><td>8.803548e-07</td><td>4.141292e-07</td><td>8.150411e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7090.01A</th><td>0.7609957</td><td>0.170439236</td><td>2.487122e-07</td><td>7.606617e-08</td><td>2.012430e-07</td><td>5.391232e-02</td><td>0.0146503680</td><td>7.609603e-07</td><td>4.567260e-07</td><td>6.395722e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.5979.01A</th><td>0.9540452</td><td>0.030934883</td><td>3.027470e-07</td><td>2.254565e-03</td><td>4.287891e-07</td><td>4.150302e-03</td><td>0.0082626311</td><td>3.480734e-04</td><td>1.029575e-06</td><td>2.583465e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.7069.01A</th><td>0.9140751</td><td>0.062127377</td><td>2.612956e-07</td><td>1.732677e-07</td><td>3.034920e-07</td><td>5.910422e-04</td><td>0.0231964752</td><td>2.621027e-06</td><td>1.160907e-06</td><td>5.503205e-06</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.4733.01A</th><td>0.5212105</td><td>0.278217146</td><td>2.304670e-02</td><td>1.216559e-02</td><td>3.143192e-07</td><td>7.464951e-02</td><td>0.0508044590</td><td>3.780930e-02</td><td>4.794581e-05</td><td>2.048584e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CR.7390.01A</th><td>0.8395196</td><td>0.150162068</td><td>2.567289e-07</td><td>1.250660e-07</td><td>2.085758e-07</td><td>2.126284e-03</td><td>0.0081897603</td><td>4.051806e-07</td><td>5.050978e-07</td><td>7.659198e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A45X.01A</th><td>0.9810586</td><td>0.008141153</td><td>3.176667e-06</td><td>5.070732e-06</td><td>4.091912e-07</td><td>3.650657e-03</td><td>0.0059594308</td><td>1.101363e-03</td><td>2.577097e-05</td><td>5.435380e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.IQ.A6SH.01A</th><td>0.9481204</td><td>0.025340661</td><td>2.249512e-06</td><td>3.035783e-07</td><td>2.650642e-07</td><td>1.328340e-02</td><td>0.0088976477</td><td>4.266965e-03</td><td>1.190798e-06</td><td>8.694332e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6962.11A</th><td>0.9318324</td><td>0.022134536</td><td>1.072486e-03</td><td>2.391896e-06</td><td>2.381979e-02</td><td>1.943510e-03</td><td>0.0155012296</td><td>2.202248e-03</td><td>8.033829e-04</td><td>6.880309e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6960.11A</th><td>0.9567643</td><td>0.006944478</td><td>9.789513e-07</td><td>4.052250e-05</td><td>9.429149e-03</td><td>4.322560e-03</td><td>0.0188890559</td><td>1.526162e-03</td><td>7.731280e-04</td><td>1.309714e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A464.01A</th><td>0.6714822</td><td>0.265287188</td><td>3.830793e-07</td><td>4.315652e-02</td><td>2.533395e-07</td><td>3.166967e-03</td><td>0.0143285239</td><td>2.547813e-03</td><td>8.301923e-07</td><td>2.927397e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.C9.A47Z.01A</th><td>0.9876402</td><td>0.001151492</td><td>1.163363e-06</td><td>3.942967e-03</td><td>4.424077e-07</td><td>9.522418e-04</td><td>0.0043511279</td><td>1.774827e-03</td><td>3.196156e-06</td><td>1.823894e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.6010.01A</th><td>0.6913758</td><td>0.079416919</td><td>7.562204e-03</td><td>1.392115e-05</td><td>1.946428e-01</td><td>4.800775e-03</td><td>0.0217729466</td><td>4.108518e-04</td><td>3.394278e-06</td><td>3.973473e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.WA.A7GZ.11A</th><td>0.5106244</td><td>0.004246898</td><td>1.363194e-07</td><td>4.777618e-01</td><td>3.409477e-04</td><td>5.787738e-07</td><td>0.0069161096</td><td>1.084712e-04</td><td>2.107773e-07</td><td>4.411246e-07</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7235.01A</th><td>0.6746427</td><td>0.282470759</td><td>2.523431e-07</td><td>9.337756e-08</td><td>2.186712e-07</td><td>1.680305e-02</td><td>0.0178143098</td><td>8.175853e-03</td><td>1.995955e-05</td><td>7.275439e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CX.7086.01A</th><td>0.9714658</td><td>0.007247442</td><td>3.184061e-04</td><td>1.531390e-05</td><td>6.731888e-07</td><td>4.688833e-03</td><td>0.0135632306</td><td>2.500719e-03</td><td>1.887139e-04</td><td>1.082412e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6935.11A</th><td>0.8982886</td><td>0.001000256</td><td>2.622110e-07</td><td>1.337033e-07</td><td>8.271160e-02</td><td>2.839132e-03</td><td>0.0139060045</td><td>6.397346e-04</td><td>3.895794e-06</td><td>6.103644e-04</td></tr>\n",
       "\t<tr><th scope=row>TCGA.P3.A6SW.01A</th><td>0.8764836</td><td>0.049837691</td><td>1.723607e-02</td><td>3.219214e-07</td><td>3.003844e-06</td><td>2.458710e-02</td><td>0.0141886382</td><td>1.577983e-02</td><td>3.578031e-04</td><td>1.525971e-03</td></tr>\n",
       "\t<tr><th scope=row>TCGA.HD.A6HZ.01A</th><td>0.7709394</td><td>0.102394643</td><td>8.480962e-03</td><td>3.720647e-02</td><td>4.300752e-07</td><td>3.512455e-02</td><td>0.0328897621</td><td>1.074326e-02</td><td>2.175530e-03</td><td>4.501833e-05</td></tr>\n",
       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "A matrix: 546 × 10 of type dbl\n",
       "\\begin{tabular}{r|llllllllll}\n",
       "  & tumor & Fibroblast & B cell & myocyte &  & Macrophage & Endothelial & T cell & Dendritic & Mast\\\\\n",
       "\\hline\n",
       "\tTCGA.BB.4224.01A & 0.98038950 & 2.594618e-03 & 3.542329e-07 & 2.766217e-03 & 3.499656e-07 & 3.205483e-03 & 0.0027510827 & 8.521628e-04 & 1.016656e-03 & 6.423578e-03\\\\\n",
       "\tTCGA.H7.7774.01A & 0.97999996 & 6.149258e-06 & 1.185681e-04 & 6.914936e-06 & 5.846047e-07 & 1.016967e-02 & 0.0035357181 & 4.121756e-03 & 4.625486e-04 & 1.578125e-03\\\\\n",
       "\tTCGA.CV.6943.01A & 0.56646958 & 3.493160e-01 & 1.944879e-03 & 4.905889e-06 & 1.315783e-07 & 4.707874e-02 & 0.0161258815 & 1.839627e-02 & 3.755185e-07 & 6.632165e-04\\\\\n",
       "\tTCGA.CN.5374.01A & 0.88892935 & 1.747085e-02 & 6.275153e-03 & 6.242288e-03 & 2.276322e-04 & 9.439050e-03 & 0.0200368767 & 3.626590e-02 & 1.486504e-02 & 2.478594e-04\\\\\n",
       "\tTCGA.CQ.6227.01A & 0.68066452 & 2.067763e-01 & 3.081748e-07 & 7.023912e-02 & 1.821531e-07 & 5.534975e-03 & 0.0367537905 & 1.512429e-06 & 4.965544e-07 & 2.884320e-05\\\\\n",
       "\tTCGA.CV.6959.01A & 0.80997894 & 6.934166e-02 & 1.838830e-04 & 6.348739e-02 & 2.532585e-07 & 1.998996e-02 & 0.0345198484 & 2.438478e-03 & 9.642066e-06 & 4.995040e-05\\\\\n",
       "\tTCGA.F7.A61V.01A & 0.92712831 & 1.167329e-02 & 1.405441e-03 & 2.250048e-02 & 2.605740e-02 & 1.886437e-03 & 0.0066788937 & 2.590494e-03 & 7.817416e-05 & 1.084985e-06\\\\\n",
       "\tTCGA.CV.7413.01A & 0.79351483 & 1.899651e-01 & 2.497154e-07 & 7.611108e-08 & 1.516735e-07 & 1.509406e-02 & 0.0002650205 & 1.158590e-03 & 6.951192e-07 & 1.209006e-06\\\\\n",
       "\tTCGA.CV.7247.01A & 0.81193494 & 8.785088e-02 & 2.399171e-07 & 7.770501e-02 & 1.929737e-07 & 4.909193e-07 & 0.0225072633 & 3.055039e-07 & 3.806278e-07 & 2.979071e-07\\\\\n",
       "\tTCGA.CR.5249.01A & 0.84617612 & 4.345764e-02 & 7.878960e-03 & 1.676177e-07 & 2.584262e-05 & 1.372778e-02 & 0.0294192277 & 3.773021e-02 & 2.083079e-02 & 7.532636e-04\\\\\n",
       "\tTCGA.CQ.5331.01A & 0.88723094 & 3.027107e-02 & 4.500219e-04 & 9.825687e-08 & 1.526343e-07 & 4.094953e-02 & 0.0282584633 & 1.282334e-02 & 2.264620e-06 & 1.412457e-05\\\\\n",
       "\tTCGA.BB.8601.01A & 0.99449058 & 3.004478e-03 & 2.596958e-04 & 4.064385e-07 & 1.139609e-06 & 5.701152e-06 & 0.0017967220 & 6.800982e-06 & 7.853000e-06 & 4.266186e-04\\\\\n",
       "\tTCGA.CV.A45W.01A & 0.75468855 & 8.971029e-02 & 4.620753e-02 & 2.030031e-07 & 1.621886e-06 & 5.955070e-02 & 0.0389652427 & 8.388750e-03 & 2.356948e-03 & 1.301651e-04\\\\\n",
       "\tTCGA.CQ.7063.01A & 0.92415516 & 1.118447e-02 & 2.787730e-07 & 4.573217e-07 & 3.122681e-07 & 3.636450e-02 & 0.0128010647 & 1.412812e-02 & 7.407397e-06 & 1.358236e-03\\\\\n",
       "\tTCGA.CN.5373.01A & 0.80822906 & 1.620342e-01 & 3.659689e-07 & 1.001210e-03 & 2.087811e-07 & 1.602183e-02 & 0.0070769511 & 4.569774e-03 & 9.695640e-07 & 1.065404e-03\\\\\n",
       "\tTCGA.CV.A45T.01A & 0.82338761 & 5.750264e-02 & 6.487877e-03 & 1.520020e-02 & 2.648398e-07 & 4.036712e-02 & 0.0227938419 & 2.991178e-02 & 2.936400e-03 & 1.412267e-03\\\\\n",
       "\tTCGA.HD.A4C1.01A & 0.90505535 & 7.572432e-02 & 5.779359e-07 & 1.074455e-07 & 1.710072e-07 & 1.424286e-03 & 0.0163282379 & 1.465662e-03 & 5.303616e-07 & 7.569981e-07\\\\\n",
       "\tTCGA.CV.7438.11A & 0.93638368 & 8.368108e-03 & 1.999069e-03 & 3.613508e-03 & 1.370744e-02 & 5.852535e-03 & 0.0107569622 & 1.061688e-02 & 6.783799e-03 & 1.918018e-03\\\\\n",
       "\tTCGA.CV.5444.01A & 0.45781938 & 4.530313e-01 & 1.842252e-07 & 3.656274e-02 & 2.025264e-07 & 4.256179e-02 & 0.0099645520 & 5.893161e-05 & 5.154288e-07 & 4.115048e-07\\\\\n",
       "\tTCGA.BA.5556.01A & 0.87839845 & 3.728688e-02 & 9.524298e-05 & 1.101190e-07 & 3.507002e-07 & 3.033017e-02 & 0.0256290186 & 2.734716e-02 & 3.962926e-04 & 5.163185e-04\\\\\n",
       "\tTCGA.P3.A6SX.01A & 0.91814480 & 6.587246e-02 & 2.774646e-07 & 1.157012e-02 & 1.856887e-07 & 3.212785e-07 & 0.0044105862 & 2.746228e-07 & 3.273847e-07 & 6.389206e-07\\\\\n",
       "\tTCGA.CV.7242.11A & 0.93168231 & 9.486023e-03 & 3.085642e-04 & 6.096573e-06 & 2.451504e-02 & 6.718584e-03 & 0.0178043874 & 5.060592e-03 & 3.867446e-03 & 5.509531e-04\\\\\n",
       "\tTCGA.DQ.7592.01A & 0.86345804 & 1.032917e-01 & 2.761607e-07 & 1.382413e-02 & 1.791237e-07 & 6.317502e-03 & 0.0090219893 & 4.071058e-03 & 1.099434e-06 & 1.407329e-05\\\\\n",
       "\tTCGA.CV.6937.01A & 0.86132265 & 1.245604e-01 & 2.852322e-07 & 3.081682e-04 & 4.121824e-07 & 9.838171e-03 & 0.0031514595 & 7.525971e-04 & 7.162633e-06 & 5.867516e-05\\\\\n",
       "\tTCGA.QK.A8ZB.01A & 0.86047924 & 1.138247e-01 & 6.991782e-03 & 7.837195e-08 & 6.567427e-07 & 4.419482e-03 & 0.0131111392 & 1.811812e-04 & 5.960970e-06 & 9.858184e-04\\\\\n",
       "\tTCGA.CV.7432.01A & 0.97786072 & 1.316335e-02 & 2.535737e-07 & 1.940134e-07 & 1.956811e-07 & 2.062597e-03 & 0.0068747131 & 1.695925e-06 & 1.465643e-06 & 3.481186e-05\\\\\n",
       "\tTCGA.CV.7089.01A & 0.95819751 & 8.616876e-03 & 3.563113e-07 & 1.938822e-07 & 2.799753e-07 & 4.091022e-03 & 0.0247870361 & 3.401242e-03 & 4.093320e-05 & 8.645486e-04\\\\\n",
       "\tTCGA.CV.6939.11A & 0.04752636 & 1.577154e-02 & 1.029359e-07 & 5.747453e-01 & 3.565640e-01 & 1.978836e-07 & 0.0053921310 & 1.012707e-07 & 1.102215e-07 & 8.236693e-08\\\\\n",
       "\tTCGA.BA.4075.01A & 0.92729488 & 3.900997e-02 & 2.596525e-07 & 2.943743e-03 & 2.705945e-07 & 2.353454e-02 & 0.0072138009 & 7.356434e-07 & 8.249225e-07 & 9.784210e-07\\\\\n",
       "\tTCGA.T3.A92M.01A & 0.70669416 & 2.534978e-01 & 1.801154e-03 & 1.151203e-07 & 2.115310e-07 & 2.353283e-02 & 0.0051027846 & 9.364755e-03 & 4.379953e-06 & 1.827037e-06\\\\\n",
       "\t⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮\\\\\n",
       "\tTCGA.CV.7430.01A & 0.9775556 & 0.012994738 & 3.468448e-07 & 3.481714e-07 & 2.987451e-07 & 7.406797e-06 & 0.0089285027 & 3.719067e-04 & 1.150469e-06 & 1.397407e-04\\\\\n",
       "\tTCGA.D6.A74Q.01A & 0.8951440 & 0.073186538 & 5.733125e-03 & 1.678243e-07 & 1.929869e-06 & 4.427085e-03 & 0.0109295967 & 7.628079e-03 & 4.126484e-06 & 2.945363e-03\\\\\n",
       "\tTCGA.CV.7255.01A & 0.9585207 & 0.016602113 & 2.803171e-07 & 9.117775e-03 & 1.327139e-06 & 8.142290e-07 & 0.0157469068 & 2.773065e-06 & 6.830472e-07 & 6.657474e-06\\\\\n",
       "\tTCGA.CQ.6223.01A & 0.9785777 & 0.006376907 & 3.504493e-04 & 1.136500e-07 & 2.677071e-07 & 6.669418e-03 & 0.0036268131 & 2.983661e-03 & 9.399514e-06 & 1.405228e-03\\\\\n",
       "\tTCGA.CV.A460.01A & 0.7679894 & 0.129785718 & 2.010091e-03 & 1.320870e-07 & 3.445873e-07 & 2.668422e-02 & 0.0292931786 & 1.162323e-02 & 3.257454e-02 & 3.913460e-05\\\\\n",
       "\tTCGA.CV.7261.01A & 0.7713323 & 0.186662086 & 1.556092e-03 & 1.611414e-07 & 1.738965e-02 & 1.025543e-02 & 0.0124651460 & 1.432732e-04 & 1.109496e-05 & 1.847530e-04\\\\\n",
       "\tTCGA.CN.4736.01A & 0.6304820 & 0.174913686 & 3.079871e-07 & 1.060600e-01 & 1.372099e-07 & 6.255270e-02 & 0.0181550094 & 7.823595e-03 & 1.984714e-06 & 1.052495e-05\\\\\n",
       "\tTCGA.CR.7404.01A & 0.8533313 & 0.041698074 & 5.792933e-03 & 1.907846e-07 & 1.271039e-05 & 3.034583e-02 & 0.0380688750 & 2.377546e-02 & 6.829564e-03 & 1.450703e-04\\\\\n",
       "\tTCGA.UF.A719.01A & 0.9690552 & 0.012148216 & 7.850680e-05 & 2.362336e-05 & 1.100021e-06 & 3.806986e-03 & 0.0124009164 & 2.460801e-03 & 1.069183e-05 & 1.396653e-05\\\\\n",
       "\tTCGA.CV.7236.01A & 0.8157329 & 0.153543909 & 6.882169e-07 & 8.274678e-08 & 5.506422e-07 & 4.877831e-03 & 0.0249209884 & 9.160930e-04 & 5.913151e-06 & 1.046194e-06\\\\\n",
       "\tTCGA.CV.6951.01A & 0.9042730 & 0.044296484 & 2.524641e-07 & 2.115219e-02 & 2.859531e-02 & 8.234009e-06 & 0.0005141088 & 2.624854e-04 & 8.164200e-07 & 8.971539e-04\\\\\n",
       "\tTCGA.CN.4728.01A & 0.3117590 & 0.583960572 & 1.911424e-07 & 5.530369e-03 & 1.610631e-07 & 8.658337e-02 & 0.0121642672 & 8.803548e-07 & 4.141292e-07 & 8.150411e-07\\\\\n",
       "\tTCGA.CV.7090.01A & 0.7609957 & 0.170439236 & 2.487122e-07 & 7.606617e-08 & 2.012430e-07 & 5.391232e-02 & 0.0146503680 & 7.609603e-07 & 4.567260e-07 & 6.395722e-07\\\\\n",
       "\tTCGA.CV.5979.01A & 0.9540452 & 0.030934883 & 3.027470e-07 & 2.254565e-03 & 4.287891e-07 & 4.150302e-03 & 0.0082626311 & 3.480734e-04 & 1.029575e-06 & 2.583465e-06\\\\\n",
       "\tTCGA.CQ.7069.01A & 0.9140751 & 0.062127377 & 2.612956e-07 & 1.732677e-07 & 3.034920e-07 & 5.910422e-04 & 0.0231964752 & 2.621027e-06 & 1.160907e-06 & 5.503205e-06\\\\\n",
       "\tTCGA.CN.4733.01A & 0.5212105 & 0.278217146 & 2.304670e-02 & 1.216559e-02 & 3.143192e-07 & 7.464951e-02 & 0.0508044590 & 3.780930e-02 & 4.794581e-05 & 2.048584e-03\\\\\n",
       "\tTCGA.CR.7390.01A & 0.8395196 & 0.150162068 & 2.567289e-07 & 1.250660e-07 & 2.085758e-07 & 2.126284e-03 & 0.0081897603 & 4.051806e-07 & 5.050978e-07 & 7.659198e-07\\\\\n",
       "\tTCGA.CV.A45X.01A & 0.9810586 & 0.008141153 & 3.176667e-06 & 5.070732e-06 & 4.091912e-07 & 3.650657e-03 & 0.0059594308 & 1.101363e-03 & 2.577097e-05 & 5.435380e-05\\\\\n",
       "\tTCGA.IQ.A6SH.01A & 0.9481204 & 0.025340661 & 2.249512e-06 & 3.035783e-07 & 2.650642e-07 & 1.328340e-02 & 0.0088976477 & 4.266965e-03 & 1.190798e-06 & 8.694332e-05\\\\\n",
       "\tTCGA.CV.6962.11A & 0.9318324 & 0.022134536 & 1.072486e-03 & 2.391896e-06 & 2.381979e-02 & 1.943510e-03 & 0.0155012296 & 2.202248e-03 & 8.033829e-04 & 6.880309e-04\\\\\n",
       "\tTCGA.CV.6960.11A & 0.9567643 & 0.006944478 & 9.789513e-07 & 4.052250e-05 & 9.429149e-03 & 4.322560e-03 & 0.0188890559 & 1.526162e-03 & 7.731280e-04 & 1.309714e-03\\\\\n",
       "\tTCGA.CV.A464.01A & 0.6714822 & 0.265287188 & 3.830793e-07 & 4.315652e-02 & 2.533395e-07 & 3.166967e-03 & 0.0143285239 & 2.547813e-03 & 8.301923e-07 & 2.927397e-05\\\\\n",
       "\tTCGA.C9.A47Z.01A & 0.9876402 & 0.001151492 & 1.163363e-06 & 3.942967e-03 & 4.424077e-07 & 9.522418e-04 & 0.0043511279 & 1.774827e-03 & 3.196156e-06 & 1.823894e-04\\\\\n",
       "\tTCGA.CN.6010.01A & 0.6913758 & 0.079416919 & 7.562204e-03 & 1.392115e-05 & 1.946428e-01 & 4.800775e-03 & 0.0217729466 & 4.108518e-04 & 3.394278e-06 & 3.973473e-07\\\\\n",
       "\tTCGA.WA.A7GZ.11A & 0.5106244 & 0.004246898 & 1.363194e-07 & 4.777618e-01 & 3.409477e-04 & 5.787738e-07 & 0.0069161096 & 1.084712e-04 & 2.107773e-07 & 4.411246e-07\\\\\n",
       "\tTCGA.CV.7235.01A & 0.6746427 & 0.282470759 & 2.523431e-07 & 9.337756e-08 & 2.186712e-07 & 1.680305e-02 & 0.0178143098 & 8.175853e-03 & 1.995955e-05 & 7.275439e-05\\\\\n",
       "\tTCGA.CX.7086.01A & 0.9714658 & 0.007247442 & 3.184061e-04 & 1.531390e-05 & 6.731888e-07 & 4.688833e-03 & 0.0135632306 & 2.500719e-03 & 1.887139e-04 & 1.082412e-05\\\\\n",
       "\tTCGA.CV.6935.11A & 0.8982886 & 0.001000256 & 2.622110e-07 & 1.337033e-07 & 8.271160e-02 & 2.839132e-03 & 0.0139060045 & 6.397346e-04 & 3.895794e-06 & 6.103644e-04\\\\\n",
       "\tTCGA.P3.A6SW.01A & 0.8764836 & 0.049837691 & 1.723607e-02 & 3.219214e-07 & 3.003844e-06 & 2.458710e-02 & 0.0141886382 & 1.577983e-02 & 3.578031e-04 & 1.525971e-03\\\\\n",
       "\tTCGA.HD.A6HZ.01A & 0.7709394 & 0.102394643 & 8.480962e-03 & 3.720647e-02 & 4.300752e-07 & 3.512455e-02 & 0.0328897621 & 1.074326e-02 & 2.175530e-03 & 4.501833e-05\\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "A matrix: 546 × 10 of type dbl\n",
       "\n",
       "| <!--/--> | tumor | Fibroblast | B cell | myocyte | <!----> | Macrophage | Endothelial | T cell | Dendritic | Mast |\n",
       "|---|---|---|---|---|---|---|---|---|---|---|\n",
       "| TCGA.BB.4224.01A | 0.98038950 | 2.594618e-03 | 3.542329e-07 | 2.766217e-03 | 3.499656e-07 | 3.205483e-03 | 0.0027510827 | 8.521628e-04 | 1.016656e-03 | 6.423578e-03 |\n",
       "| TCGA.H7.7774.01A | 0.97999996 | 6.149258e-06 | 1.185681e-04 | 6.914936e-06 | 5.846047e-07 | 1.016967e-02 | 0.0035357181 | 4.121756e-03 | 4.625486e-04 | 1.578125e-03 |\n",
       "| TCGA.CV.6943.01A | 0.56646958 | 3.493160e-01 | 1.944879e-03 | 4.905889e-06 | 1.315783e-07 | 4.707874e-02 | 0.0161258815 | 1.839627e-02 | 3.755185e-07 | 6.632165e-04 |\n",
       "| TCGA.CN.5374.01A | 0.88892935 | 1.747085e-02 | 6.275153e-03 | 6.242288e-03 | 2.276322e-04 | 9.439050e-03 | 0.0200368767 | 3.626590e-02 | 1.486504e-02 | 2.478594e-04 |\n",
       "| TCGA.CQ.6227.01A | 0.68066452 | 2.067763e-01 | 3.081748e-07 | 7.023912e-02 | 1.821531e-07 | 5.534975e-03 | 0.0367537905 | 1.512429e-06 | 4.965544e-07 | 2.884320e-05 |\n",
       "| TCGA.CV.6959.01A | 0.80997894 | 6.934166e-02 | 1.838830e-04 | 6.348739e-02 | 2.532585e-07 | 1.998996e-02 | 0.0345198484 | 2.438478e-03 | 9.642066e-06 | 4.995040e-05 |\n",
       "| TCGA.F7.A61V.01A | 0.92712831 | 1.167329e-02 | 1.405441e-03 | 2.250048e-02 | 2.605740e-02 | 1.886437e-03 | 0.0066788937 | 2.590494e-03 | 7.817416e-05 | 1.084985e-06 |\n",
       "| TCGA.CV.7413.01A | 0.79351483 | 1.899651e-01 | 2.497154e-07 | 7.611108e-08 | 1.516735e-07 | 1.509406e-02 | 0.0002650205 | 1.158590e-03 | 6.951192e-07 | 1.209006e-06 |\n",
       "| TCGA.CV.7247.01A | 0.81193494 | 8.785088e-02 | 2.399171e-07 | 7.770501e-02 | 1.929737e-07 | 4.909193e-07 | 0.0225072633 | 3.055039e-07 | 3.806278e-07 | 2.979071e-07 |\n",
       "| TCGA.CR.5249.01A | 0.84617612 | 4.345764e-02 | 7.878960e-03 | 1.676177e-07 | 2.584262e-05 | 1.372778e-02 | 0.0294192277 | 3.773021e-02 | 2.083079e-02 | 7.532636e-04 |\n",
       "| TCGA.CQ.5331.01A | 0.88723094 | 3.027107e-02 | 4.500219e-04 | 9.825687e-08 | 1.526343e-07 | 4.094953e-02 | 0.0282584633 | 1.282334e-02 | 2.264620e-06 | 1.412457e-05 |\n",
       "| TCGA.BB.8601.01A | 0.99449058 | 3.004478e-03 | 2.596958e-04 | 4.064385e-07 | 1.139609e-06 | 5.701152e-06 | 0.0017967220 | 6.800982e-06 | 7.853000e-06 | 4.266186e-04 |\n",
       "| TCGA.CV.A45W.01A | 0.75468855 | 8.971029e-02 | 4.620753e-02 | 2.030031e-07 | 1.621886e-06 | 5.955070e-02 | 0.0389652427 | 8.388750e-03 | 2.356948e-03 | 1.301651e-04 |\n",
       "| TCGA.CQ.7063.01A | 0.92415516 | 1.118447e-02 | 2.787730e-07 | 4.573217e-07 | 3.122681e-07 | 3.636450e-02 | 0.0128010647 | 1.412812e-02 | 7.407397e-06 | 1.358236e-03 |\n",
       "| TCGA.CN.5373.01A | 0.80822906 | 1.620342e-01 | 3.659689e-07 | 1.001210e-03 | 2.087811e-07 | 1.602183e-02 | 0.0070769511 | 4.569774e-03 | 9.695640e-07 | 1.065404e-03 |\n",
       "| TCGA.CV.A45T.01A | 0.82338761 | 5.750264e-02 | 6.487877e-03 | 1.520020e-02 | 2.648398e-07 | 4.036712e-02 | 0.0227938419 | 2.991178e-02 | 2.936400e-03 | 1.412267e-03 |\n",
       "| TCGA.HD.A4C1.01A | 0.90505535 | 7.572432e-02 | 5.779359e-07 | 1.074455e-07 | 1.710072e-07 | 1.424286e-03 | 0.0163282379 | 1.465662e-03 | 5.303616e-07 | 7.569981e-07 |\n",
       "| TCGA.CV.7438.11A | 0.93638368 | 8.368108e-03 | 1.999069e-03 | 3.613508e-03 | 1.370744e-02 | 5.852535e-03 | 0.0107569622 | 1.061688e-02 | 6.783799e-03 | 1.918018e-03 |\n",
       "| TCGA.CV.5444.01A | 0.45781938 | 4.530313e-01 | 1.842252e-07 | 3.656274e-02 | 2.025264e-07 | 4.256179e-02 | 0.0099645520 | 5.893161e-05 | 5.154288e-07 | 4.115048e-07 |\n",
       "| TCGA.BA.5556.01A | 0.87839845 | 3.728688e-02 | 9.524298e-05 | 1.101190e-07 | 3.507002e-07 | 3.033017e-02 | 0.0256290186 | 2.734716e-02 | 3.962926e-04 | 5.163185e-04 |\n",
       "| TCGA.P3.A6SX.01A | 0.91814480 | 6.587246e-02 | 2.774646e-07 | 1.157012e-02 | 1.856887e-07 | 3.212785e-07 | 0.0044105862 | 2.746228e-07 | 3.273847e-07 | 6.389206e-07 |\n",
       "| TCGA.CV.7242.11A | 0.93168231 | 9.486023e-03 | 3.085642e-04 | 6.096573e-06 | 2.451504e-02 | 6.718584e-03 | 0.0178043874 | 5.060592e-03 | 3.867446e-03 | 5.509531e-04 |\n",
       "| TCGA.DQ.7592.01A | 0.86345804 | 1.032917e-01 | 2.761607e-07 | 1.382413e-02 | 1.791237e-07 | 6.317502e-03 | 0.0090219893 | 4.071058e-03 | 1.099434e-06 | 1.407329e-05 |\n",
       "| TCGA.CV.6937.01A | 0.86132265 | 1.245604e-01 | 2.852322e-07 | 3.081682e-04 | 4.121824e-07 | 9.838171e-03 | 0.0031514595 | 7.525971e-04 | 7.162633e-06 | 5.867516e-05 |\n",
       "| TCGA.QK.A8ZB.01A | 0.86047924 | 1.138247e-01 | 6.991782e-03 | 7.837195e-08 | 6.567427e-07 | 4.419482e-03 | 0.0131111392 | 1.811812e-04 | 5.960970e-06 | 9.858184e-04 |\n",
       "| TCGA.CV.7432.01A | 0.97786072 | 1.316335e-02 | 2.535737e-07 | 1.940134e-07 | 1.956811e-07 | 2.062597e-03 | 0.0068747131 | 1.695925e-06 | 1.465643e-06 | 3.481186e-05 |\n",
       "| TCGA.CV.7089.01A | 0.95819751 | 8.616876e-03 | 3.563113e-07 | 1.938822e-07 | 2.799753e-07 | 4.091022e-03 | 0.0247870361 | 3.401242e-03 | 4.093320e-05 | 8.645486e-04 |\n",
       "| TCGA.CV.6939.11A | 0.04752636 | 1.577154e-02 | 1.029359e-07 | 5.747453e-01 | 3.565640e-01 | 1.978836e-07 | 0.0053921310 | 1.012707e-07 | 1.102215e-07 | 8.236693e-08 |\n",
       "| TCGA.BA.4075.01A | 0.92729488 | 3.900997e-02 | 2.596525e-07 | 2.943743e-03 | 2.705945e-07 | 2.353454e-02 | 0.0072138009 | 7.356434e-07 | 8.249225e-07 | 9.784210e-07 |\n",
       "| TCGA.T3.A92M.01A | 0.70669416 | 2.534978e-01 | 1.801154e-03 | 1.151203e-07 | 2.115310e-07 | 2.353283e-02 | 0.0051027846 | 9.364755e-03 | 4.379953e-06 | 1.827037e-06 |\n",
       "| ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ |\n",
       "| TCGA.CV.7430.01A | 0.9775556 | 0.012994738 | 3.468448e-07 | 3.481714e-07 | 2.987451e-07 | 7.406797e-06 | 0.0089285027 | 3.719067e-04 | 1.150469e-06 | 1.397407e-04 |\n",
       "| TCGA.D6.A74Q.01A | 0.8951440 | 0.073186538 | 5.733125e-03 | 1.678243e-07 | 1.929869e-06 | 4.427085e-03 | 0.0109295967 | 7.628079e-03 | 4.126484e-06 | 2.945363e-03 |\n",
       "| TCGA.CV.7255.01A | 0.9585207 | 0.016602113 | 2.803171e-07 | 9.117775e-03 | 1.327139e-06 | 8.142290e-07 | 0.0157469068 | 2.773065e-06 | 6.830472e-07 | 6.657474e-06 |\n",
       "| TCGA.CQ.6223.01A | 0.9785777 | 0.006376907 | 3.504493e-04 | 1.136500e-07 | 2.677071e-07 | 6.669418e-03 | 0.0036268131 | 2.983661e-03 | 9.399514e-06 | 1.405228e-03 |\n",
       "| TCGA.CV.A460.01A | 0.7679894 | 0.129785718 | 2.010091e-03 | 1.320870e-07 | 3.445873e-07 | 2.668422e-02 | 0.0292931786 | 1.162323e-02 | 3.257454e-02 | 3.913460e-05 |\n",
       "| TCGA.CV.7261.01A | 0.7713323 | 0.186662086 | 1.556092e-03 | 1.611414e-07 | 1.738965e-02 | 1.025543e-02 | 0.0124651460 | 1.432732e-04 | 1.109496e-05 | 1.847530e-04 |\n",
       "| TCGA.CN.4736.01A | 0.6304820 | 0.174913686 | 3.079871e-07 | 1.060600e-01 | 1.372099e-07 | 6.255270e-02 | 0.0181550094 | 7.823595e-03 | 1.984714e-06 | 1.052495e-05 |\n",
       "| TCGA.CR.7404.01A | 0.8533313 | 0.041698074 | 5.792933e-03 | 1.907846e-07 | 1.271039e-05 | 3.034583e-02 | 0.0380688750 | 2.377546e-02 | 6.829564e-03 | 1.450703e-04 |\n",
       "| TCGA.UF.A719.01A | 0.9690552 | 0.012148216 | 7.850680e-05 | 2.362336e-05 | 1.100021e-06 | 3.806986e-03 | 0.0124009164 | 2.460801e-03 | 1.069183e-05 | 1.396653e-05 |\n",
       "| TCGA.CV.7236.01A | 0.8157329 | 0.153543909 | 6.882169e-07 | 8.274678e-08 | 5.506422e-07 | 4.877831e-03 | 0.0249209884 | 9.160930e-04 | 5.913151e-06 | 1.046194e-06 |\n",
       "| TCGA.CV.6951.01A | 0.9042730 | 0.044296484 | 2.524641e-07 | 2.115219e-02 | 2.859531e-02 | 8.234009e-06 | 0.0005141088 | 2.624854e-04 | 8.164200e-07 | 8.971539e-04 |\n",
       "| TCGA.CN.4728.01A | 0.3117590 | 0.583960572 | 1.911424e-07 | 5.530369e-03 | 1.610631e-07 | 8.658337e-02 | 0.0121642672 | 8.803548e-07 | 4.141292e-07 | 8.150411e-07 |\n",
       "| TCGA.CV.7090.01A | 0.7609957 | 0.170439236 | 2.487122e-07 | 7.606617e-08 | 2.012430e-07 | 5.391232e-02 | 0.0146503680 | 7.609603e-07 | 4.567260e-07 | 6.395722e-07 |\n",
       "| TCGA.CV.5979.01A | 0.9540452 | 0.030934883 | 3.027470e-07 | 2.254565e-03 | 4.287891e-07 | 4.150302e-03 | 0.0082626311 | 3.480734e-04 | 1.029575e-06 | 2.583465e-06 |\n",
       "| TCGA.CQ.7069.01A | 0.9140751 | 0.062127377 | 2.612956e-07 | 1.732677e-07 | 3.034920e-07 | 5.910422e-04 | 0.0231964752 | 2.621027e-06 | 1.160907e-06 | 5.503205e-06 |\n",
       "| TCGA.CN.4733.01A | 0.5212105 | 0.278217146 | 2.304670e-02 | 1.216559e-02 | 3.143192e-07 | 7.464951e-02 | 0.0508044590 | 3.780930e-02 | 4.794581e-05 | 2.048584e-03 |\n",
       "| TCGA.CR.7390.01A | 0.8395196 | 0.150162068 | 2.567289e-07 | 1.250660e-07 | 2.085758e-07 | 2.126284e-03 | 0.0081897603 | 4.051806e-07 | 5.050978e-07 | 7.659198e-07 |\n",
       "| TCGA.CV.A45X.01A | 0.9810586 | 0.008141153 | 3.176667e-06 | 5.070732e-06 | 4.091912e-07 | 3.650657e-03 | 0.0059594308 | 1.101363e-03 | 2.577097e-05 | 5.435380e-05 |\n",
       "| TCGA.IQ.A6SH.01A | 0.9481204 | 0.025340661 | 2.249512e-06 | 3.035783e-07 | 2.650642e-07 | 1.328340e-02 | 0.0088976477 | 4.266965e-03 | 1.190798e-06 | 8.694332e-05 |\n",
       "| TCGA.CV.6962.11A | 0.9318324 | 0.022134536 | 1.072486e-03 | 2.391896e-06 | 2.381979e-02 | 1.943510e-03 | 0.0155012296 | 2.202248e-03 | 8.033829e-04 | 6.880309e-04 |\n",
       "| TCGA.CV.6960.11A | 0.9567643 | 0.006944478 | 9.789513e-07 | 4.052250e-05 | 9.429149e-03 | 4.322560e-03 | 0.0188890559 | 1.526162e-03 | 7.731280e-04 | 1.309714e-03 |\n",
       "| TCGA.CV.A464.01A | 0.6714822 | 0.265287188 | 3.830793e-07 | 4.315652e-02 | 2.533395e-07 | 3.166967e-03 | 0.0143285239 | 2.547813e-03 | 8.301923e-07 | 2.927397e-05 |\n",
       "| TCGA.C9.A47Z.01A | 0.9876402 | 0.001151492 | 1.163363e-06 | 3.942967e-03 | 4.424077e-07 | 9.522418e-04 | 0.0043511279 | 1.774827e-03 | 3.196156e-06 | 1.823894e-04 |\n",
       "| TCGA.CN.6010.01A | 0.6913758 | 0.079416919 | 7.562204e-03 | 1.392115e-05 | 1.946428e-01 | 4.800775e-03 | 0.0217729466 | 4.108518e-04 | 3.394278e-06 | 3.973473e-07 |\n",
       "| TCGA.WA.A7GZ.11A | 0.5106244 | 0.004246898 | 1.363194e-07 | 4.777618e-01 | 3.409477e-04 | 5.787738e-07 | 0.0069161096 | 1.084712e-04 | 2.107773e-07 | 4.411246e-07 |\n",
       "| TCGA.CV.7235.01A | 0.6746427 | 0.282470759 | 2.523431e-07 | 9.337756e-08 | 2.186712e-07 | 1.680305e-02 | 0.0178143098 | 8.175853e-03 | 1.995955e-05 | 7.275439e-05 |\n",
       "| TCGA.CX.7086.01A | 0.9714658 | 0.007247442 | 3.184061e-04 | 1.531390e-05 | 6.731888e-07 | 4.688833e-03 | 0.0135632306 | 2.500719e-03 | 1.887139e-04 | 1.082412e-05 |\n",
       "| TCGA.CV.6935.11A | 0.8982886 | 0.001000256 | 2.622110e-07 | 1.337033e-07 | 8.271160e-02 | 2.839132e-03 | 0.0139060045 | 6.397346e-04 | 3.895794e-06 | 6.103644e-04 |\n",
       "| TCGA.P3.A6SW.01A | 0.8764836 | 0.049837691 | 1.723607e-02 | 3.219214e-07 | 3.003844e-06 | 2.458710e-02 | 0.0141886382 | 1.577983e-02 | 3.578031e-04 | 1.525971e-03 |\n",
       "| TCGA.HD.A6HZ.01A | 0.7709394 | 0.102394643 | 8.480962e-03 | 3.720647e-02 | 4.300752e-07 | 3.512455e-02 | 0.0328897621 | 1.074326e-02 | 2.175530e-03 | 4.501833e-05 |\n",
       "\n"
      ],
      "text/plain": [
       "                 tumor      Fibroblast   B cell       myocyte                  \n",
       "TCGA.BB.4224.01A 0.98038950 2.594618e-03 3.542329e-07 2.766217e-03 3.499656e-07\n",
       "TCGA.H7.7774.01A 0.97999996 6.149258e-06 1.185681e-04 6.914936e-06 5.846047e-07\n",
       "TCGA.CV.6943.01A 0.56646958 3.493160e-01 1.944879e-03 4.905889e-06 1.315783e-07\n",
       "TCGA.CN.5374.01A 0.88892935 1.747085e-02 6.275153e-03 6.242288e-03 2.276322e-04\n",
       "TCGA.CQ.6227.01A 0.68066452 2.067763e-01 3.081748e-07 7.023912e-02 1.821531e-07\n",
       "TCGA.CV.6959.01A 0.80997894 6.934166e-02 1.838830e-04 6.348739e-02 2.532585e-07\n",
       "TCGA.F7.A61V.01A 0.92712831 1.167329e-02 1.405441e-03 2.250048e-02 2.605740e-02\n",
       "TCGA.CV.7413.01A 0.79351483 1.899651e-01 2.497154e-07 7.611108e-08 1.516735e-07\n",
       "TCGA.CV.7247.01A 0.81193494 8.785088e-02 2.399171e-07 7.770501e-02 1.929737e-07\n",
       "TCGA.CR.5249.01A 0.84617612 4.345764e-02 7.878960e-03 1.676177e-07 2.584262e-05\n",
       "TCGA.CQ.5331.01A 0.88723094 3.027107e-02 4.500219e-04 9.825687e-08 1.526343e-07\n",
       "TCGA.BB.8601.01A 0.99449058 3.004478e-03 2.596958e-04 4.064385e-07 1.139609e-06\n",
       "TCGA.CV.A45W.01A 0.75468855 8.971029e-02 4.620753e-02 2.030031e-07 1.621886e-06\n",
       "TCGA.CQ.7063.01A 0.92415516 1.118447e-02 2.787730e-07 4.573217e-07 3.122681e-07\n",
       "TCGA.CN.5373.01A 0.80822906 1.620342e-01 3.659689e-07 1.001210e-03 2.087811e-07\n",
       "TCGA.CV.A45T.01A 0.82338761 5.750264e-02 6.487877e-03 1.520020e-02 2.648398e-07\n",
       "TCGA.HD.A4C1.01A 0.90505535 7.572432e-02 5.779359e-07 1.074455e-07 1.710072e-07\n",
       "TCGA.CV.7438.11A 0.93638368 8.368108e-03 1.999069e-03 3.613508e-03 1.370744e-02\n",
       "TCGA.CV.5444.01A 0.45781938 4.530313e-01 1.842252e-07 3.656274e-02 2.025264e-07\n",
       "TCGA.BA.5556.01A 0.87839845 3.728688e-02 9.524298e-05 1.101190e-07 3.507002e-07\n",
       "TCGA.P3.A6SX.01A 0.91814480 6.587246e-02 2.774646e-07 1.157012e-02 1.856887e-07\n",
       "TCGA.CV.7242.11A 0.93168231 9.486023e-03 3.085642e-04 6.096573e-06 2.451504e-02\n",
       "TCGA.DQ.7592.01A 0.86345804 1.032917e-01 2.761607e-07 1.382413e-02 1.791237e-07\n",
       "TCGA.CV.6937.01A 0.86132265 1.245604e-01 2.852322e-07 3.081682e-04 4.121824e-07\n",
       "TCGA.QK.A8ZB.01A 0.86047924 1.138247e-01 6.991782e-03 7.837195e-08 6.567427e-07\n",
       "TCGA.CV.7432.01A 0.97786072 1.316335e-02 2.535737e-07 1.940134e-07 1.956811e-07\n",
       "TCGA.CV.7089.01A 0.95819751 8.616876e-03 3.563113e-07 1.938822e-07 2.799753e-07\n",
       "TCGA.CV.6939.11A 0.04752636 1.577154e-02 1.029359e-07 5.747453e-01 3.565640e-01\n",
       "TCGA.BA.4075.01A 0.92729488 3.900997e-02 2.596525e-07 2.943743e-03 2.705945e-07\n",
       "TCGA.T3.A92M.01A 0.70669416 2.534978e-01 1.801154e-03 1.151203e-07 2.115310e-07\n",
       "⋮                ⋮          ⋮            ⋮            ⋮            ⋮           \n",
       "TCGA.CV.7430.01A 0.9775556  0.012994738  3.468448e-07 3.481714e-07 2.987451e-07\n",
       "TCGA.D6.A74Q.01A 0.8951440  0.073186538  5.733125e-03 1.678243e-07 1.929869e-06\n",
       "TCGA.CV.7255.01A 0.9585207  0.016602113  2.803171e-07 9.117775e-03 1.327139e-06\n",
       "TCGA.CQ.6223.01A 0.9785777  0.006376907  3.504493e-04 1.136500e-07 2.677071e-07\n",
       "TCGA.CV.A460.01A 0.7679894  0.129785718  2.010091e-03 1.320870e-07 3.445873e-07\n",
       "TCGA.CV.7261.01A 0.7713323  0.186662086  1.556092e-03 1.611414e-07 1.738965e-02\n",
       "TCGA.CN.4736.01A 0.6304820  0.174913686  3.079871e-07 1.060600e-01 1.372099e-07\n",
       "TCGA.CR.7404.01A 0.8533313  0.041698074  5.792933e-03 1.907846e-07 1.271039e-05\n",
       "TCGA.UF.A719.01A 0.9690552  0.012148216  7.850680e-05 2.362336e-05 1.100021e-06\n",
       "TCGA.CV.7236.01A 0.8157329  0.153543909  6.882169e-07 8.274678e-08 5.506422e-07\n",
       "TCGA.CV.6951.01A 0.9042730  0.044296484  2.524641e-07 2.115219e-02 2.859531e-02\n",
       "TCGA.CN.4728.01A 0.3117590  0.583960572  1.911424e-07 5.530369e-03 1.610631e-07\n",
       "TCGA.CV.7090.01A 0.7609957  0.170439236  2.487122e-07 7.606617e-08 2.012430e-07\n",
       "TCGA.CV.5979.01A 0.9540452  0.030934883  3.027470e-07 2.254565e-03 4.287891e-07\n",
       "TCGA.CQ.7069.01A 0.9140751  0.062127377  2.612956e-07 1.732677e-07 3.034920e-07\n",
       "TCGA.CN.4733.01A 0.5212105  0.278217146  2.304670e-02 1.216559e-02 3.143192e-07\n",
       "TCGA.CR.7390.01A 0.8395196  0.150162068  2.567289e-07 1.250660e-07 2.085758e-07\n",
       "TCGA.CV.A45X.01A 0.9810586  0.008141153  3.176667e-06 5.070732e-06 4.091912e-07\n",
       "TCGA.IQ.A6SH.01A 0.9481204  0.025340661  2.249512e-06 3.035783e-07 2.650642e-07\n",
       "TCGA.CV.6962.11A 0.9318324  0.022134536  1.072486e-03 2.391896e-06 2.381979e-02\n",
       "TCGA.CV.6960.11A 0.9567643  0.006944478  9.789513e-07 4.052250e-05 9.429149e-03\n",
       "TCGA.CV.A464.01A 0.6714822  0.265287188  3.830793e-07 4.315652e-02 2.533395e-07\n",
       "TCGA.C9.A47Z.01A 0.9876402  0.001151492  1.163363e-06 3.942967e-03 4.424077e-07\n",
       "TCGA.CN.6010.01A 0.6913758  0.079416919  7.562204e-03 1.392115e-05 1.946428e-01\n",
       "TCGA.WA.A7GZ.11A 0.5106244  0.004246898  1.363194e-07 4.777618e-01 3.409477e-04\n",
       "TCGA.CV.7235.01A 0.6746427  0.282470759  2.523431e-07 9.337756e-08 2.186712e-07\n",
       "TCGA.CX.7086.01A 0.9714658  0.007247442  3.184061e-04 1.531390e-05 6.731888e-07\n",
       "TCGA.CV.6935.11A 0.8982886  0.001000256  2.622110e-07 1.337033e-07 8.271160e-02\n",
       "TCGA.P3.A6SW.01A 0.8764836  0.049837691  1.723607e-02 3.219214e-07 3.003844e-06\n",
       "TCGA.HD.A6HZ.01A 0.7709394  0.102394643  8.480962e-03 3.720647e-02 4.300752e-07\n",
       "                 Macrophage   Endothelial  T cell       Dendritic   \n",
       "TCGA.BB.4224.01A 3.205483e-03 0.0027510827 8.521628e-04 1.016656e-03\n",
       "TCGA.H7.7774.01A 1.016967e-02 0.0035357181 4.121756e-03 4.625486e-04\n",
       "TCGA.CV.6943.01A 4.707874e-02 0.0161258815 1.839627e-02 3.755185e-07\n",
       "TCGA.CN.5374.01A 9.439050e-03 0.0200368767 3.626590e-02 1.486504e-02\n",
       "TCGA.CQ.6227.01A 5.534975e-03 0.0367537905 1.512429e-06 4.965544e-07\n",
       "TCGA.CV.6959.01A 1.998996e-02 0.0345198484 2.438478e-03 9.642066e-06\n",
       "TCGA.F7.A61V.01A 1.886437e-03 0.0066788937 2.590494e-03 7.817416e-05\n",
       "TCGA.CV.7413.01A 1.509406e-02 0.0002650205 1.158590e-03 6.951192e-07\n",
       "TCGA.CV.7247.01A 4.909193e-07 0.0225072633 3.055039e-07 3.806278e-07\n",
       "TCGA.CR.5249.01A 1.372778e-02 0.0294192277 3.773021e-02 2.083079e-02\n",
       "TCGA.CQ.5331.01A 4.094953e-02 0.0282584633 1.282334e-02 2.264620e-06\n",
       "TCGA.BB.8601.01A 5.701152e-06 0.0017967220 6.800982e-06 7.853000e-06\n",
       "TCGA.CV.A45W.01A 5.955070e-02 0.0389652427 8.388750e-03 2.356948e-03\n",
       "TCGA.CQ.7063.01A 3.636450e-02 0.0128010647 1.412812e-02 7.407397e-06\n",
       "TCGA.CN.5373.01A 1.602183e-02 0.0070769511 4.569774e-03 9.695640e-07\n",
       "TCGA.CV.A45T.01A 4.036712e-02 0.0227938419 2.991178e-02 2.936400e-03\n",
       "TCGA.HD.A4C1.01A 1.424286e-03 0.0163282379 1.465662e-03 5.303616e-07\n",
       "TCGA.CV.7438.11A 5.852535e-03 0.0107569622 1.061688e-02 6.783799e-03\n",
       "TCGA.CV.5444.01A 4.256179e-02 0.0099645520 5.893161e-05 5.154288e-07\n",
       "TCGA.BA.5556.01A 3.033017e-02 0.0256290186 2.734716e-02 3.962926e-04\n",
       "TCGA.P3.A6SX.01A 3.212785e-07 0.0044105862 2.746228e-07 3.273847e-07\n",
       "TCGA.CV.7242.11A 6.718584e-03 0.0178043874 5.060592e-03 3.867446e-03\n",
       "TCGA.DQ.7592.01A 6.317502e-03 0.0090219893 4.071058e-03 1.099434e-06\n",
       "TCGA.CV.6937.01A 9.838171e-03 0.0031514595 7.525971e-04 7.162633e-06\n",
       "TCGA.QK.A8ZB.01A 4.419482e-03 0.0131111392 1.811812e-04 5.960970e-06\n",
       "TCGA.CV.7432.01A 2.062597e-03 0.0068747131 1.695925e-06 1.465643e-06\n",
       "TCGA.CV.7089.01A 4.091022e-03 0.0247870361 3.401242e-03 4.093320e-05\n",
       "TCGA.CV.6939.11A 1.978836e-07 0.0053921310 1.012707e-07 1.102215e-07\n",
       "TCGA.BA.4075.01A 2.353454e-02 0.0072138009 7.356434e-07 8.249225e-07\n",
       "TCGA.T3.A92M.01A 2.353283e-02 0.0051027846 9.364755e-03 4.379953e-06\n",
       "⋮                ⋮            ⋮            ⋮            ⋮           \n",
       "TCGA.CV.7430.01A 7.406797e-06 0.0089285027 3.719067e-04 1.150469e-06\n",
       "TCGA.D6.A74Q.01A 4.427085e-03 0.0109295967 7.628079e-03 4.126484e-06\n",
       "TCGA.CV.7255.01A 8.142290e-07 0.0157469068 2.773065e-06 6.830472e-07\n",
       "TCGA.CQ.6223.01A 6.669418e-03 0.0036268131 2.983661e-03 9.399514e-06\n",
       "TCGA.CV.A460.01A 2.668422e-02 0.0292931786 1.162323e-02 3.257454e-02\n",
       "TCGA.CV.7261.01A 1.025543e-02 0.0124651460 1.432732e-04 1.109496e-05\n",
       "TCGA.CN.4736.01A 6.255270e-02 0.0181550094 7.823595e-03 1.984714e-06\n",
       "TCGA.CR.7404.01A 3.034583e-02 0.0380688750 2.377546e-02 6.829564e-03\n",
       "TCGA.UF.A719.01A 3.806986e-03 0.0124009164 2.460801e-03 1.069183e-05\n",
       "TCGA.CV.7236.01A 4.877831e-03 0.0249209884 9.160930e-04 5.913151e-06\n",
       "TCGA.CV.6951.01A 8.234009e-06 0.0005141088 2.624854e-04 8.164200e-07\n",
       "TCGA.CN.4728.01A 8.658337e-02 0.0121642672 8.803548e-07 4.141292e-07\n",
       "TCGA.CV.7090.01A 5.391232e-02 0.0146503680 7.609603e-07 4.567260e-07\n",
       "TCGA.CV.5979.01A 4.150302e-03 0.0082626311 3.480734e-04 1.029575e-06\n",
       "TCGA.CQ.7069.01A 5.910422e-04 0.0231964752 2.621027e-06 1.160907e-06\n",
       "TCGA.CN.4733.01A 7.464951e-02 0.0508044590 3.780930e-02 4.794581e-05\n",
       "TCGA.CR.7390.01A 2.126284e-03 0.0081897603 4.051806e-07 5.050978e-07\n",
       "TCGA.CV.A45X.01A 3.650657e-03 0.0059594308 1.101363e-03 2.577097e-05\n",
       "TCGA.IQ.A6SH.01A 1.328340e-02 0.0088976477 4.266965e-03 1.190798e-06\n",
       "TCGA.CV.6962.11A 1.943510e-03 0.0155012296 2.202248e-03 8.033829e-04\n",
       "TCGA.CV.6960.11A 4.322560e-03 0.0188890559 1.526162e-03 7.731280e-04\n",
       "TCGA.CV.A464.01A 3.166967e-03 0.0143285239 2.547813e-03 8.301923e-07\n",
       "TCGA.C9.A47Z.01A 9.522418e-04 0.0043511279 1.774827e-03 3.196156e-06\n",
       "TCGA.CN.6010.01A 4.800775e-03 0.0217729466 4.108518e-04 3.394278e-06\n",
       "TCGA.WA.A7GZ.11A 5.787738e-07 0.0069161096 1.084712e-04 2.107773e-07\n",
       "TCGA.CV.7235.01A 1.680305e-02 0.0178143098 8.175853e-03 1.995955e-05\n",
       "TCGA.CX.7086.01A 4.688833e-03 0.0135632306 2.500719e-03 1.887139e-04\n",
       "TCGA.CV.6935.11A 2.839132e-03 0.0139060045 6.397346e-04 3.895794e-06\n",
       "TCGA.P3.A6SW.01A 2.458710e-02 0.0141886382 1.577983e-02 3.578031e-04\n",
       "TCGA.HD.A6HZ.01A 3.512455e-02 0.0328897621 1.074326e-02 2.175530e-03\n",
       "                 Mast        \n",
       "TCGA.BB.4224.01A 6.423578e-03\n",
       "TCGA.H7.7774.01A 1.578125e-03\n",
       "TCGA.CV.6943.01A 6.632165e-04\n",
       "TCGA.CN.5374.01A 2.478594e-04\n",
       "TCGA.CQ.6227.01A 2.884320e-05\n",
       "TCGA.CV.6959.01A 4.995040e-05\n",
       "TCGA.F7.A61V.01A 1.084985e-06\n",
       "TCGA.CV.7413.01A 1.209006e-06\n",
       "TCGA.CV.7247.01A 2.979071e-07\n",
       "TCGA.CR.5249.01A 7.532636e-04\n",
       "TCGA.CQ.5331.01A 1.412457e-05\n",
       "TCGA.BB.8601.01A 4.266186e-04\n",
       "TCGA.CV.A45W.01A 1.301651e-04\n",
       "TCGA.CQ.7063.01A 1.358236e-03\n",
       "TCGA.CN.5373.01A 1.065404e-03\n",
       "TCGA.CV.A45T.01A 1.412267e-03\n",
       "TCGA.HD.A4C1.01A 7.569981e-07\n",
       "TCGA.CV.7438.11A 1.918018e-03\n",
       "TCGA.CV.5444.01A 4.115048e-07\n",
       "TCGA.BA.5556.01A 5.163185e-04\n",
       "TCGA.P3.A6SX.01A 6.389206e-07\n",
       "TCGA.CV.7242.11A 5.509531e-04\n",
       "TCGA.DQ.7592.01A 1.407329e-05\n",
       "TCGA.CV.6937.01A 5.867516e-05\n",
       "TCGA.QK.A8ZB.01A 9.858184e-04\n",
       "TCGA.CV.7432.01A 3.481186e-05\n",
       "TCGA.CV.7089.01A 8.645486e-04\n",
       "TCGA.CV.6939.11A 8.236693e-08\n",
       "TCGA.BA.4075.01A 9.784210e-07\n",
       "TCGA.T3.A92M.01A 1.827037e-06\n",
       "⋮                ⋮           \n",
       "TCGA.CV.7430.01A 1.397407e-04\n",
       "TCGA.D6.A74Q.01A 2.945363e-03\n",
       "TCGA.CV.7255.01A 6.657474e-06\n",
       "TCGA.CQ.6223.01A 1.405228e-03\n",
       "TCGA.CV.A460.01A 3.913460e-05\n",
       "TCGA.CV.7261.01A 1.847530e-04\n",
       "TCGA.CN.4736.01A 1.052495e-05\n",
       "TCGA.CR.7404.01A 1.450703e-04\n",
       "TCGA.UF.A719.01A 1.396653e-05\n",
       "TCGA.CV.7236.01A 1.046194e-06\n",
       "TCGA.CV.6951.01A 8.971539e-04\n",
       "TCGA.CN.4728.01A 8.150411e-07\n",
       "TCGA.CV.7090.01A 6.395722e-07\n",
       "TCGA.CV.5979.01A 2.583465e-06\n",
       "TCGA.CQ.7069.01A 5.503205e-06\n",
       "TCGA.CN.4733.01A 2.048584e-03\n",
       "TCGA.CR.7390.01A 7.659198e-07\n",
       "TCGA.CV.A45X.01A 5.435380e-05\n",
       "TCGA.IQ.A6SH.01A 8.694332e-05\n",
       "TCGA.CV.6962.11A 6.880309e-04\n",
       "TCGA.CV.6960.11A 1.309714e-03\n",
       "TCGA.CV.A464.01A 2.927397e-05\n",
       "TCGA.C9.A47Z.01A 1.823894e-04\n",
       "TCGA.CN.6010.01A 3.973473e-07\n",
       "TCGA.WA.A7GZ.11A 4.411246e-07\n",
       "TCGA.CV.7235.01A 7.275439e-05\n",
       "TCGA.CX.7086.01A 1.082412e-05\n",
       "TCGA.CV.6935.11A 6.103644e-04\n",
       "TCGA.P3.A6SW.01A 1.525971e-03\n",
       "TCGA.HD.A6HZ.01A 4.501833e-05"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "# the updated estimates of cell type fraction\n",
    "res1$res$final.gibbs.thet"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 7,
   "id": "64b847e9",
   "metadata": {
    "collapsed": true
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<table class=\"dataframe\">\n",
       "<caption>A matrix: 546 × 18234 of type dbl</caption>\n",
       "<thead>\n",
       "\t<tr><th></th><th scope=col>ENSG00000121410</th><th scope=col>ENSG00000268895</th><th scope=col>ENSG00000148584</th><th scope=col>ENSG00000175899</th><th scope=col>ENSG00000245105</th><th scope=col>ENSG00000166535</th><th scope=col>ENSG00000256069</th><th scope=col>ENSG00000128274</th><th scope=col>ENSG00000118017</th><th scope=col>ENSG00000094914</th><th scope=col>⋯</th><th scope=col>ENSG00000153975</th><th scope=col>ENSG00000086827</th><th scope=col>ENSG00000174442</th><th scope=col>ENSG00000122952</th><th scope=col>ENSG00000070476</th><th scope=col>ENSG00000203995</th><th scope=col>ENSG00000162378</th><th scope=col>ENSG00000159840</th><th scope=col>ENSG00000074755</th><th scope=col>ENSG00000036549</th></tr>\n",
       "</thead>\n",
       "<tbody>\n",
       "\t<tr><th scope=row>TCGA.BB.4224.01A</th><td>7.112896e-07</td><td>1.816119e-06</td><td>9.364097e-08</td><td>3.621218e-05</td><td>1.604931e-07</td><td>1.463920e-04</td><td>1.728192e-08</td><td>8.595791e-06</td><td>1.113401e-07</td><td>4.816970e-05</td><td>⋯</td><td>1.688383e-05</td><td>4.109552e-05</td><td>4.948895e-05</td><td>2.232009e-04</td><td>6.436126e-05</td><td>8.086158e-06</td><td>4.401456e-05</td><td>6.694816e-05</td><td>4.885926e-05</td><td>5.912475e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.H7.7774.01A</th><td>1.000000e-08</td><td>3.055765e-07</td><td>1.000000e-08</td><td>2.999947e-05</td><td>9.831822e-08</td><td>2.973466e-03</td><td>1.810790e-08</td><td>6.325584e-05</td><td>1.000000e-08</td><td>2.424271e-05</td><td>⋯</td><td>8.324437e-06</td><td>2.991585e-05</td><td>1.176516e-05</td><td>2.554113e-05</td><td>1.917238e-05</td><td>1.049839e-06</td><td>3.525809e-05</td><td>2.250746e-04</td><td>7.796061e-05</td><td>2.826495e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6943.01A</th><td>4.240591e-07</td><td>2.095767e-06</td><td>2.250067e-08</td><td>1.192457e-05</td><td>1.112711e-08</td><td>6.257739e-04</td><td>1.563555e-08</td><td>5.036751e-05</td><td>1.174190e-08</td><td>4.004534e-05</td><td>⋯</td><td>8.202857e-06</td><td>2.796816e-05</td><td>2.079954e-05</td><td>3.936395e-05</td><td>1.792602e-05</td><td>5.487945e-08</td><td>1.907782e-05</td><td>2.410835e-04</td><td>8.432179e-05</td><td>3.307693e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.5374.01A</th><td>5.688623e-07</td><td>3.710153e-06</td><td>7.632998e-08</td><td>2.041327e-05</td><td>4.276067e-07</td><td>3.069937e-04</td><td>8.693131e-08</td><td>1.711497e-04</td><td>8.105760e-08</td><td>5.006406e-05</td><td>⋯</td><td>1.198679e-05</td><td>2.319999e-05</td><td>5.350305e-05</td><td>1.639979e-04</td><td>5.114597e-05</td><td>5.912365e-06</td><td>2.957125e-05</td><td>1.426902e-04</td><td>5.812695e-05</td><td>8.976578e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.6227.01A</th><td>2.332942e-07</td><td>3.722853e-06</td><td>4.673325e-08</td><td>1.603208e-05</td><td>2.147914e-08</td><td>9.793864e-04</td><td>1.199637e-08</td><td>6.991207e-05</td><td>1.000000e-08</td><td>3.144777e-05</td><td>⋯</td><td>1.177592e-05</td><td>3.476145e-05</td><td>3.677868e-05</td><td>4.817377e-05</td><td>1.521257e-05</td><td>8.158356e-07</td><td>3.049380e-05</td><td>3.080264e-04</td><td>5.208826e-05</td><td>4.512052e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6959.01A</th><td>1.095189e-07</td><td>1.099285e-06</td><td>3.631508e-08</td><td>1.009195e-05</td><td>2.834081e-08</td><td>1.569075e-04</td><td>1.382765e-08</td><td>6.221136e-05</td><td>1.000000e-08</td><td>4.816301e-05</td><td>⋯</td><td>1.093267e-05</td><td>2.184035e-05</td><td>5.181435e-05</td><td>6.009834e-05</td><td>3.105542e-05</td><td>5.593178e-08</td><td>2.774777e-05</td><td>3.850048e-04</td><td>7.340731e-05</td><td>5.111540e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.F7.A61V.01A</th><td>6.488749e-08</td><td>8.260607e-07</td><td>2.762901e-08</td><td>1.661053e-05</td><td>6.526258e-08</td><td>6.957961e-04</td><td>5.576042e-08</td><td>1.660799e-04</td><td>1.000000e-08</td><td>4.595533e-05</td><td>⋯</td><td>1.254223e-05</td><td>3.845450e-05</td><td>3.403099e-05</td><td>8.593618e-05</td><td>5.133781e-05</td><td>7.236624e-07</td><td>2.285670e-05</td><td>1.580313e-04</td><td>4.675939e-05</td><td>4.992411e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7413.01A</th><td>7.152449e-07</td><td>4.564537e-06</td><td>6.039585e-08</td><td>1.069679e-05</td><td>1.346533e-08</td><td>2.421368e-04</td><td>2.089105e-08</td><td>9.714023e-06</td><td>2.237619e-08</td><td>7.070657e-05</td><td>⋯</td><td>1.180174e-05</td><td>3.282413e-05</td><td>3.526789e-05</td><td>4.109272e-05</td><td>3.621323e-05</td><td>7.663341e-08</td><td>2.347080e-05</td><td>1.550597e-04</td><td>6.976865e-05</td><td>4.175598e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7247.01A</th><td>6.327757e-08</td><td>4.347303e-07</td><td>1.000000e-08</td><td>1.534071e-05</td><td>1.596113e-08</td><td>3.955346e-04</td><td>1.102457e-08</td><td>6.344039e-05</td><td>1.000000e-08</td><td>3.543493e-05</td><td>⋯</td><td>8.242409e-06</td><td>2.878184e-05</td><td>5.191763e-05</td><td>9.079134e-05</td><td>2.787398e-05</td><td>1.784460e-06</td><td>2.728132e-05</td><td>1.733255e-04</td><td>5.414169e-05</td><td>6.122369e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CR.5249.01A</th><td>1.204938e-07</td><td>1.304003e-06</td><td>1.000000e-08</td><td>1.972672e-05</td><td>2.524341e-07</td><td>1.275800e-03</td><td>4.587590e-08</td><td>3.842528e-05</td><td>1.000000e-08</td><td>4.347034e-05</td><td>⋯</td><td>1.001275e-05</td><td>2.092357e-05</td><td>4.553226e-05</td><td>1.109087e-04</td><td>4.417026e-05</td><td>4.727433e-06</td><td>4.064770e-05</td><td>2.483755e-04</td><td>9.212467e-05</td><td>5.698468e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.5331.01A</th><td>4.904080e-07</td><td>3.904193e-06</td><td>1.000000e-08</td><td>3.802067e-05</td><td>1.775944e-08</td><td>3.547654e-04</td><td>1.277123e-08</td><td>1.600670e-05</td><td>1.615829e-08</td><td>3.917818e-05</td><td>⋯</td><td>1.344621e-05</td><td>3.188899e-05</td><td>3.083241e-05</td><td>4.320952e-05</td><td>2.665635e-05</td><td>1.130897e-07</td><td>3.676192e-05</td><td>1.451680e-04</td><td>1.057671e-04</td><td>4.379419e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.BB.8601.01A</th><td>2.489795e-07</td><td>1.399710e-06</td><td>1.000000e-08</td><td>1.816752e-05</td><td>2.899112e-07</td><td>2.987224e-04</td><td>1.000000e-08</td><td>1.210167e-04</td><td>5.644774e-07</td><td>6.030766e-05</td><td>⋯</td><td>1.576661e-05</td><td>3.774724e-05</td><td>5.166895e-05</td><td>4.469663e-05</td><td>6.560713e-05</td><td>2.364771e-06</td><td>1.835305e-05</td><td>2.435944e-04</td><td>3.309973e-05</td><td>3.577703e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A45W.01A</th><td>3.341896e-07</td><td>1.505259e-06</td><td>4.588118e-08</td><td>1.477458e-05</td><td>7.129353e-07</td><td>7.860505e-04</td><td>1.965225e-08</td><td>6.933357e-04</td><td>1.000000e-08</td><td>7.564479e-05</td><td>⋯</td><td>1.219932e-05</td><td>3.475431e-05</td><td>4.183087e-05</td><td>6.151852e-05</td><td>5.860921e-05</td><td>5.503807e-06</td><td>2.351070e-05</td><td>1.689415e-04</td><td>5.725936e-05</td><td>4.625916e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.7063.01A</th><td>2.367013e-07</td><td>7.131626e-07</td><td>6.225785e-08</td><td>3.921091e-05</td><td>1.375956e-08</td><td>4.148020e-04</td><td>1.000000e-08</td><td>6.779595e-05</td><td>1.000000e-08</td><td>3.503893e-05</td><td>⋯</td><td>1.220162e-05</td><td>3.380328e-05</td><td>2.501544e-05</td><td>3.378373e-05</td><td>2.725200e-05</td><td>1.246665e-07</td><td>2.473861e-05</td><td>3.740954e-04</td><td>8.947594e-05</td><td>3.327431e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.5373.01A</th><td>1.110500e-07</td><td>1.395054e-06</td><td>1.000000e-08</td><td>1.920272e-05</td><td>1.323611e-08</td><td>6.928735e-04</td><td>1.135708e-08</td><td>1.851542e-05</td><td>1.647221e-08</td><td>2.462936e-05</td><td>⋯</td><td>8.555410e-06</td><td>2.546115e-05</td><td>1.713736e-05</td><td>2.721261e-05</td><td>3.433372e-05</td><td>2.469665e-07</td><td>3.476788e-05</td><td>1.786924e-04</td><td>8.323724e-05</td><td>3.471464e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A45T.01A</th><td>2.311965e-07</td><td>2.848872e-06</td><td>1.000000e-08</td><td>1.690396e-05</td><td>2.381714e-08</td><td>5.877619e-04</td><td>2.650720e-08</td><td>3.745090e-05</td><td>1.000000e-08</td><td>4.425150e-05</td><td>⋯</td><td>9.461779e-06</td><td>3.674317e-05</td><td>2.409327e-05</td><td>6.648291e-05</td><td>2.232908e-05</td><td>2.283842e-07</td><td>2.562306e-05</td><td>2.979540e-04</td><td>5.079728e-05</td><td>4.287382e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.HD.A4C1.01A</th><td>1.133506e-07</td><td>8.143151e-07</td><td>2.952519e-08</td><td>9.147686e-06</td><td>1.848477e-08</td><td>1.824253e-03</td><td>1.000000e-08</td><td>2.050174e-05</td><td>1.531576e-08</td><td>3.385155e-05</td><td>⋯</td><td>1.375154e-05</td><td>3.996538e-05</td><td>4.140943e-05</td><td>5.820150e-05</td><td>3.268607e-05</td><td>2.484935e-07</td><td>4.006986e-05</td><td>2.865009e-04</td><td>8.858985e-05</td><td>5.208715e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7438.11A</th><td>2.849850e-08</td><td>7.780335e-07</td><td>1.000000e-08</td><td>2.511091e-05</td><td>4.068676e-08</td><td>2.306430e-03</td><td>3.835284e-08</td><td>4.069788e-05</td><td>1.000000e-08</td><td>3.582102e-05</td><td>⋯</td><td>9.986137e-06</td><td>3.280438e-05</td><td>2.201708e-05</td><td>2.936764e-05</td><td>1.825384e-05</td><td>7.567689e-07</td><td>2.819463e-05</td><td>2.549497e-04</td><td>6.962642e-05</td><td>4.188256e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.5444.01A</th><td>6.977180e-08</td><td>9.184345e-07</td><td>6.541596e-08</td><td>1.556131e-05</td><td>1.387186e-08</td><td>3.781312e-05</td><td>1.701774e-08</td><td>2.746558e-05</td><td>1.532380e-08</td><td>5.458818e-05</td><td>⋯</td><td>1.109198e-05</td><td>3.447969e-05</td><td>3.425125e-05</td><td>9.014054e-05</td><td>4.267545e-05</td><td>1.694721e-07</td><td>3.367386e-05</td><td>2.155933e-04</td><td>6.592546e-05</td><td>5.377485e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.BA.5556.01A</th><td>1.399434e-07</td><td>2.567673e-06</td><td>2.498744e-08</td><td>2.442414e-05</td><td>1.227558e-08</td><td>5.432007e-04</td><td>1.133396e-08</td><td>1.018834e-04</td><td>1.000000e-08</td><td>3.673644e-05</td><td>⋯</td><td>9.226567e-06</td><td>3.810100e-05</td><td>2.496581e-05</td><td>4.480619e-05</td><td>2.826359e-05</td><td>9.223473e-08</td><td>3.382087e-05</td><td>3.820152e-04</td><td>1.145747e-04</td><td>3.953509e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.P3.A6SX.01A</th><td>5.295955e-07</td><td>3.703059e-06</td><td>4.578755e-08</td><td>1.191229e-05</td><td>1.730174e-08</td><td>7.153822e-05</td><td>2.153855e-08</td><td>2.714021e-05</td><td>2.135826e-08</td><td>6.914316e-05</td><td>⋯</td><td>1.010506e-05</td><td>2.535398e-05</td><td>4.251470e-05</td><td>7.067788e-05</td><td>4.601701e-05</td><td>2.759241e-06</td><td>2.782909e-05</td><td>1.228729e-04</td><td>5.473565e-05</td><td>6.273034e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7242.11A</th><td>1.447966e-07</td><td>3.584082e-07</td><td>1.842479e-08</td><td>1.848186e-05</td><td>3.684909e-08</td><td>1.828910e-03</td><td>1.385808e-08</td><td>1.005487e-04</td><td>1.000000e-08</td><td>3.572110e-05</td><td>⋯</td><td>9.388835e-06</td><td>3.151705e-05</td><td>2.339004e-05</td><td>4.435776e-05</td><td>1.519887e-05</td><td>4.655684e-07</td><td>2.436527e-05</td><td>2.302738e-04</td><td>6.842738e-05</td><td>3.747306e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.DQ.7592.01A</th><td>1.734400e-07</td><td>1.155176e-06</td><td>2.337038e-08</td><td>1.387800e-05</td><td>2.285894e-08</td><td>1.638256e-04</td><td>2.147076e-08</td><td>6.279202e-05</td><td>1.000000e-08</td><td>3.828361e-05</td><td>⋯</td><td>1.246155e-05</td><td>2.848459e-05</td><td>2.688416e-05</td><td>5.692476e-05</td><td>3.370240e-05</td><td>1.622993e-06</td><td>3.422983e-05</td><td>3.782780e-04</td><td>9.691256e-05</td><td>5.087237e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6937.01A</th><td>8.198938e-07</td><td>4.949553e-06</td><td>3.752314e-08</td><td>1.347374e-05</td><td>5.451273e-08</td><td>3.051719e-05</td><td>1.254844e-08</td><td>2.385506e-05</td><td>2.444115e-08</td><td>5.597677e-05</td><td>⋯</td><td>1.083458e-05</td><td>2.587512e-05</td><td>1.330435e-05</td><td>4.541689e-05</td><td>6.192550e-05</td><td>4.148619e-07</td><td>4.509375e-05</td><td>2.291824e-04</td><td>6.211986e-05</td><td>3.248849e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.QK.A8ZB.01A</th><td>2.837068e-07</td><td>1.510805e-06</td><td>5.124242e-08</td><td>1.222917e-05</td><td>2.405815e-08</td><td>2.458834e-04</td><td>2.957268e-08</td><td>5.870644e-05</td><td>1.489317e-08</td><td>4.413466e-05</td><td>⋯</td><td>1.438504e-05</td><td>4.190057e-05</td><td>3.191098e-05</td><td>3.159906e-05</td><td>3.714488e-05</td><td>7.877809e-07</td><td>3.547662e-05</td><td>1.745106e-04</td><td>5.561768e-05</td><td>4.968794e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7432.01A</th><td>2.393062e-07</td><td>1.143573e-06</td><td>1.000000e-08</td><td>1.585025e-05</td><td>3.435764e-08</td><td>6.326612e-05</td><td>1.229634e-08</td><td>9.838101e-06</td><td>1.000000e-08</td><td>5.061828e-05</td><td>⋯</td><td>7.323606e-06</td><td>2.347354e-05</td><td>2.809034e-05</td><td>6.897467e-05</td><td>2.389131e-05</td><td>2.754048e-06</td><td>1.806278e-05</td><td>4.240103e-04</td><td>6.424363e-05</td><td>6.081059e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7089.01A</th><td>8.247095e-08</td><td>1.471344e-06</td><td>2.661754e-08</td><td>2.982818e-05</td><td>1.246186e-08</td><td>1.587486e-03</td><td>1.038467e-08</td><td>3.785445e-05</td><td>1.000000e-08</td><td>4.696895e-05</td><td>⋯</td><td>8.723132e-06</td><td>2.817704e-05</td><td>3.291789e-05</td><td>6.626445e-05</td><td>3.203185e-05</td><td>3.701237e-07</td><td>2.995689e-05</td><td>3.655372e-04</td><td>5.180273e-05</td><td>3.228027e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6939.11A</th><td>1.000000e-08</td><td>1.000000e-08</td><td>1.000000e-08</td><td>1.000000e-08</td><td>1.000000e-08</td><td>1.000000e-08</td><td>1.000000e-08</td><td>3.745671e-04</td><td>1.000000e-08</td><td>1.000000e-08</td><td>⋯</td><td>1.000000e-08</td><td>1.000000e-08</td><td>1.000000e-08</td><td>1.000000e-08</td><td>1.000000e-08</td><td>1.000000e-08</td><td>1.000000e-08</td><td>1.000000e-08</td><td>1.248624e-04</td><td>1.000000e-08</td></tr>\n",
       "\t<tr><th scope=row>TCGA.BA.4075.01A</th><td>8.208282e-08</td><td>2.119095e-06</td><td>1.737547e-07</td><td>1.032987e-06</td><td>2.971715e-08</td><td>3.250782e-06</td><td>1.652970e-08</td><td>2.960736e-05</td><td>1.512134e-08</td><td>3.313814e-05</td><td>⋯</td><td>1.279785e-05</td><td>2.892712e-05</td><td>4.382560e-05</td><td>4.240033e-05</td><td>1.784301e-05</td><td>8.361922e-08</td><td>2.020586e-05</td><td>2.721516e-04</td><td>1.280451e-05</td><td>5.767805e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.T3.A92M.01A</th><td>1.105985e-06</td><td>3.734028e-06</td><td>8.654651e-08</td><td>9.104048e-06</td><td>7.268756e-08</td><td>1.311396e-05</td><td>2.305319e-08</td><td>2.892186e-05</td><td>7.268756e-08</td><td>5.626057e-05</td><td>⋯</td><td>1.786274e-05</td><td>2.432842e-05</td><td>4.703002e-05</td><td>1.091200e-04</td><td>6.208567e-05</td><td>3.187889e-06</td><td>3.233632e-05</td><td>1.889197e-04</td><td>6.236092e-05</td><td>3.629111e-05</td></tr>\n",
       "\t<tr><th scope=row>⋮</th><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋱</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td><td>⋮</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7430.01A</th><td>5.992312e-08</td><td>4.316190e-07</td><td>4.100343e-08</td><td>1.423256e-05</td><td>7.614986e-08</td><td>8.471157e-04</td><td>1.000000e-08</td><td>6.978670e-05</td><td>2.042654e-08</td><td>3.853621e-05</td><td>⋯</td><td>1.264069e-05</td><td>3.960967e-05</td><td>3.717462e-05</td><td>4.984853e-05</td><td>4.044724e-05</td><td>3.036183e-06</td><td>3.712124e-05</td><td>2.335524e-04</td><td>8.635110e-05</td><td>5.497010e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.D6.A74Q.01A</th><td>5.906717e-07</td><td>3.218203e-06</td><td>1.000000e-08</td><td>5.075967e-06</td><td>4.651282e-08</td><td>2.866994e-04</td><td>2.156418e-08</td><td>1.291496e-04</td><td>1.000000e-08</td><td>5.972753e-05</td><td>⋯</td><td>1.532419e-05</td><td>2.926941e-05</td><td>3.902315e-05</td><td>1.499300e-04</td><td>3.898235e-05</td><td>3.639974e-06</td><td>1.956117e-05</td><td>3.995424e-04</td><td>3.777732e-05</td><td>3.815455e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7255.01A</th><td>1.000000e-08</td><td>4.927327e-08</td><td>2.262154e-08</td><td>7.523477e-06</td><td>3.039731e-08</td><td>2.023672e-04</td><td>1.129596e-08</td><td>9.066132e-05</td><td>1.000000e-08</td><td>4.400175e-05</td><td>⋯</td><td>1.139795e-05</td><td>3.899337e-05</td><td>3.734795e-05</td><td>4.424697e-05</td><td>4.001470e-05</td><td>7.762513e-07</td><td>4.356174e-05</td><td>3.151445e-04</td><td>8.641293e-05</td><td>5.587264e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.6223.01A</th><td>1.357241e-07</td><td>8.593188e-07</td><td>4.068498e-08</td><td>2.909884e-05</td><td>2.524518e-08</td><td>5.389829e-04</td><td>2.076894e-08</td><td>1.237306e-05</td><td>1.000000e-08</td><td>2.535573e-05</td><td>⋯</td><td>9.995334e-06</td><td>2.695394e-05</td><td>2.243365e-05</td><td>4.489370e-05</td><td>4.750166e-05</td><td>2.506792e-07</td><td>2.826659e-05</td><td>3.110916e-04</td><td>5.003158e-05</td><td>3.253504e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A460.01A</th><td>1.563773e-07</td><td>1.277916e-06</td><td>1.000000e-08</td><td>9.654251e-06</td><td>5.704522e-07</td><td>4.379689e-04</td><td>1.035673e-07</td><td>6.906425e-05</td><td>3.664289e-08</td><td>6.853885e-05</td><td>⋯</td><td>1.474273e-05</td><td>2.165545e-05</td><td>3.136948e-05</td><td>5.283001e-05</td><td>4.540727e-05</td><td>2.012023e-06</td><td>3.496452e-05</td><td>1.878741e-04</td><td>5.432899e-05</td><td>5.297623e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7261.01A</th><td>1.665030e-07</td><td>3.901885e-07</td><td>2.906323e-08</td><td>1.132787e-05</td><td>3.359198e-07</td><td>2.860075e-04</td><td>1.230604e-08</td><td>1.498001e-04</td><td>1.618909e-07</td><td>4.263600e-05</td><td>⋯</td><td>1.691570e-05</td><td>5.612231e-05</td><td>5.952034e-05</td><td>6.640847e-05</td><td>6.396268e-05</td><td>3.700491e-07</td><td>2.714467e-05</td><td>3.126007e-04</td><td>6.837413e-05</td><td>4.239125e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.4736.01A</th><td>2.406184e-07</td><td>7.075260e-07</td><td>5.304101e-08</td><td>3.287152e-05</td><td>1.261736e-08</td><td>2.536685e-04</td><td>2.366843e-08</td><td>1.693020e-05</td><td>1.959698e-08</td><td>3.909167e-05</td><td>⋯</td><td>8.256569e-06</td><td>3.579729e-05</td><td>2.999039e-05</td><td>5.166633e-05</td><td>3.844707e-05</td><td>3.312000e-08</td><td>5.097928e-05</td><td>2.352842e-04</td><td>9.728805e-05</td><td>5.721484e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CR.7404.01A</th><td>2.021346e-07</td><td>1.770215e-06</td><td>2.311015e-08</td><td>2.722137e-05</td><td>1.746742e-07</td><td>2.898410e-04</td><td>1.593500e-08</td><td>5.946127e-05</td><td>2.311015e-08</td><td>4.793213e-05</td><td>⋯</td><td>6.406515e-06</td><td>2.989495e-05</td><td>5.368581e-05</td><td>1.027929e-04</td><td>8.676051e-05</td><td>8.699464e-06</td><td>3.976442e-05</td><td>2.060475e-04</td><td>1.076988e-04</td><td>6.827457e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.UF.A719.01A</th><td>2.287460e-07</td><td>1.194490e-06</td><td>4.452210e-08</td><td>1.156790e-05</td><td>1.795083e-07</td><td>6.265976e-04</td><td>1.000000e-08</td><td>1.573143e-04</td><td>1.014756e-07</td><td>3.996623e-05</td><td>⋯</td><td>2.240991e-05</td><td>3.083760e-05</td><td>4.057689e-05</td><td>8.318972e-05</td><td>5.420023e-05</td><td>5.502195e-06</td><td>2.682675e-05</td><td>2.526194e-04</td><td>7.717047e-05</td><td>3.166247e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7236.01A</th><td>1.415668e-07</td><td>3.236452e-06</td><td>2.480716e-08</td><td>1.586300e-05</td><td>1.113176e-08</td><td>6.024393e-05</td><td>1.000000e-08</td><td>3.476194e-05</td><td>1.000000e-08</td><td>3.685805e-05</td><td>⋯</td><td>1.254780e-05</td><td>4.125521e-05</td><td>2.973344e-05</td><td>5.050591e-05</td><td>3.414947e-05</td><td>7.139785e-08</td><td>2.926980e-05</td><td>3.100679e-04</td><td>1.012570e-04</td><td>5.451327e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6951.01A</th><td>4.044799e-07</td><td>4.174614e-06</td><td>1.000000e-08</td><td>1.927283e-05</td><td>2.988900e-07</td><td>6.876290e-04</td><td>2.264854e-07</td><td>1.099859e-04</td><td>1.950685e-07</td><td>3.673897e-05</td><td>⋯</td><td>9.771089e-06</td><td>3.152647e-05</td><td>1.785293e-05</td><td>2.334205e-05</td><td>4.515652e-05</td><td>8.247592e-07</td><td>2.676806e-05</td><td>2.145656e-04</td><td>1.010798e-04</td><td>6.089078e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.4728.01A</th><td>4.336213e-07</td><td>2.660096e-06</td><td>6.812478e-08</td><td>1.024489e-05</td><td>3.758464e-08</td><td>1.189281e-03</td><td>2.247877e-08</td><td>8.836066e-05</td><td>1.919488e-08</td><td>3.754712e-05</td><td>⋯</td><td>8.126781e-06</td><td>2.912493e-05</td><td>3.314047e-05</td><td>7.982748e-05</td><td>5.703698e-05</td><td>7.166923e-07</td><td>2.742946e-05</td><td>2.034198e-04</td><td>6.571169e-05</td><td>4.317406e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7090.01A</th><td>1.294972e-07</td><td>6.863691e-07</td><td>1.000000e-08</td><td>1.133545e-05</td><td>1.345653e-08</td><td>2.727092e-05</td><td>1.185171e-08</td><td>5.001848e-06</td><td>1.333308e-08</td><td>3.332022e-05</td><td>⋯</td><td>8.960687e-06</td><td>2.090016e-05</td><td>4.915027e-05</td><td>4.212438e-05</td><td>3.918176e-05</td><td>1.000000e-08</td><td>3.281396e-05</td><td>4.687791e-04</td><td>6.574890e-05</td><td>3.779211e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.5979.01A</th><td>2.645943e-08</td><td>3.037834e-08</td><td>3.028037e-08</td><td>2.998465e-06</td><td>2.743916e-08</td><td>2.418532e-04</td><td>1.558445e-08</td><td>5.951702e-05</td><td>1.000000e-08</td><td>4.779614e-05</td><td>⋯</td><td>8.988522e-06</td><td>1.272109e-05</td><td>3.512541e-05</td><td>3.674373e-05</td><td>3.024813e-05</td><td>3.771041e-07</td><td>3.516098e-05</td><td>4.204467e-04</td><td>4.820018e-05</td><td>4.464063e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CQ.7069.01A</th><td>1.744712e-07</td><td>1.541398e-06</td><td>8.156685e-08</td><td>8.556673e-06</td><td>1.490365e-08</td><td>1.430076e-04</td><td>1.662656e-08</td><td>1.105873e-05</td><td>1.000000e-08</td><td>2.536097e-05</td><td>⋯</td><td>1.264765e-05</td><td>2.414579e-05</td><td>3.010678e-05</td><td>2.258006e-05</td><td>3.145634e-05</td><td>3.153519e-07</td><td>2.720858e-05</td><td>4.259971e-04</td><td>4.564460e-05</td><td>2.595895e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.4733.01A</th><td>8.847056e-08</td><td>1.419331e-06</td><td>2.457310e-08</td><td>1.331480e-05</td><td>1.313882e-08</td><td>3.572621e-05</td><td>1.022420e-08</td><td>6.077850e-05</td><td>1.560504e-08</td><td>5.411276e-05</td><td>⋯</td><td>1.382351e-05</td><td>4.042234e-05</td><td>2.912594e-05</td><td>9.503942e-05</td><td>2.637745e-05</td><td>8.398653e-08</td><td>2.558109e-05</td><td>3.552050e-04</td><td>8.559336e-05</td><td>4.522407e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CR.7390.01A</th><td>7.033687e-08</td><td>2.668394e-07</td><td>1.000000e-08</td><td>6.803786e-06</td><td>7.595381e-08</td><td>1.617098e-03</td><td>1.154013e-08</td><td>9.424985e-05</td><td>4.234274e-08</td><td>2.279786e-05</td><td>⋯</td><td>8.722879e-06</td><td>3.009699e-05</td><td>4.232997e-05</td><td>6.324648e-05</td><td>4.315285e-05</td><td>2.235216e-06</td><td>3.633153e-05</td><td>2.488503e-04</td><td>4.194766e-05</td><td>4.857112e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A45X.01A</th><td>6.251957e-08</td><td>3.740855e-07</td><td>8.813362e-08</td><td>1.553685e-05</td><td>1.721068e-08</td><td>9.506332e-04</td><td>4.174851e-08</td><td>6.365759e-05</td><td>1.000000e-08</td><td>2.879255e-05</td><td>⋯</td><td>1.206260e-05</td><td>3.156587e-05</td><td>2.067817e-05</td><td>3.839815e-05</td><td>4.571709e-05</td><td>1.516817e-06</td><td>4.216944e-05</td><td>1.323282e-04</td><td>5.792434e-05</td><td>4.926701e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.IQ.A6SH.01A</th><td>1.096632e-07</td><td>1.939058e-06</td><td>1.000000e-08</td><td>1.250559e-05</td><td>2.979841e-08</td><td>2.678809e-04</td><td>2.185667e-08</td><td>1.076140e-04</td><td>1.000000e-08</td><td>6.607560e-05</td><td>⋯</td><td>1.609883e-05</td><td>3.553158e-05</td><td>2.347749e-05</td><td>3.265119e-05</td><td>2.525442e-05</td><td>4.322541e-07</td><td>1.931993e-05</td><td>2.521374e-04</td><td>3.989081e-05</td><td>3.527331e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6962.11A</th><td>5.200397e-08</td><td>2.035130e-07</td><td>1.000000e-08</td><td>2.857071e-05</td><td>7.698528e-08</td><td>4.107892e-03</td><td>1.000000e-08</td><td>1.346954e-04</td><td>1.000000e-08</td><td>2.744051e-05</td><td>⋯</td><td>5.120336e-06</td><td>2.686948e-05</td><td>1.576429e-05</td><td>2.542071e-05</td><td>1.756936e-05</td><td>1.320524e-06</td><td>2.958898e-05</td><td>1.754682e-04</td><td>7.299102e-05</td><td>2.940011e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6960.11A</th><td>3.402361e-08</td><td>2.908119e-07</td><td>2.436819e-08</td><td>3.046435e-05</td><td>2.873612e-08</td><td>2.513120e-03</td><td>1.172418e-08</td><td>6.795268e-05</td><td>1.000000e-08</td><td>3.238705e-05</td><td>⋯</td><td>9.303920e-06</td><td>2.819361e-05</td><td>2.395568e-05</td><td>3.186382e-05</td><td>2.138331e-05</td><td>3.633425e-07</td><td>3.495539e-05</td><td>3.200481e-04</td><td>9.644285e-05</td><td>4.983267e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.A464.01A</th><td>1.817166e-07</td><td>2.650198e-06</td><td>4.178302e-08</td><td>1.272615e-05</td><td>1.353145e-08</td><td>3.495293e-05</td><td>2.839295e-08</td><td>1.456133e-05</td><td>1.161858e-08</td><td>6.225308e-05</td><td>⋯</td><td>1.449747e-05</td><td>3.969405e-05</td><td>4.049480e-05</td><td>5.752197e-05</td><td>2.347514e-05</td><td>2.336583e-07</td><td>2.786002e-05</td><td>2.649415e-04</td><td>4.804563e-05</td><td>3.662360e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.C9.A47Z.01A</th><td>1.384600e-07</td><td>1.939077e-06</td><td>1.000000e-08</td><td>3.848765e-05</td><td>1.478949e-07</td><td>7.352721e-04</td><td>1.642818e-08</td><td>1.322168e-05</td><td>1.000000e-08</td><td>4.057763e-05</td><td>⋯</td><td>1.064781e-05</td><td>3.285023e-05</td><td>3.109866e-05</td><td>2.854366e-05</td><td>4.843298e-05</td><td>2.555151e-07</td><td>3.217569e-05</td><td>1.967548e-04</td><td>7.272145e-05</td><td>4.140324e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CN.6010.01A</th><td>1.632860e-07</td><td>9.065136e-07</td><td>2.032884e-08</td><td>1.705648e-05</td><td>3.956101e-07</td><td>9.547081e-05</td><td>1.194601e-08</td><td>2.303115e-04</td><td>3.718089e-07</td><td>4.849059e-05</td><td>⋯</td><td>8.693862e-06</td><td>3.882429e-05</td><td>7.222762e-05</td><td>8.577996e-05</td><td>3.221383e-05</td><td>1.778063e-07</td><td>2.927056e-05</td><td>1.852030e-04</td><td>9.048408e-05</td><td>5.164957e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.WA.A7GZ.11A</th><td>2.786106e-07</td><td>1.206237e-06</td><td>1.425476e-07</td><td>9.061288e-06</td><td>1.184732e-06</td><td>3.604722e-03</td><td>6.955339e-08</td><td>3.738554e-05</td><td>4.143095e-08</td><td>1.680033e-05</td><td>⋯</td><td>1.017895e-05</td><td>3.332661e-05</td><td>1.974347e-05</td><td>2.994902e-05</td><td>1.621741e-05</td><td>9.469319e-07</td><td>1.216002e-04</td><td>7.325901e-05</td><td>5.763307e-05</td><td>4.442421e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.7235.01A</th><td>5.456606e-07</td><td>2.264343e-06</td><td>1.000000e-08</td><td>1.476062e-05</td><td>1.830712e-08</td><td>6.823170e-06</td><td>1.044502e-08</td><td>2.685593e-05</td><td>1.000000e-08</td><td>2.724191e-05</td><td>⋯</td><td>7.464746e-06</td><td>1.738329e-05</td><td>5.189980e-05</td><td>3.644026e-05</td><td>2.241993e-05</td><td>4.246480e-06</td><td>3.151444e-05</td><td>3.181916e-04</td><td>7.806484e-05</td><td>5.641338e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CX.7086.01A</th><td>1.147891e-07</td><td>1.070028e-06</td><td>2.687282e-08</td><td>2.155978e-05</td><td>9.007191e-08</td><td>9.884022e-04</td><td>2.361666e-08</td><td>1.391071e-04</td><td>1.000000e-08</td><td>5.256944e-05</td><td>⋯</td><td>1.074008e-05</td><td>2.238995e-05</td><td>3.763070e-05</td><td>4.660105e-05</td><td>5.250173e-05</td><td>8.732214e-06</td><td>3.691013e-05</td><td>2.525940e-04</td><td>5.755536e-05</td><td>4.827834e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.CV.6935.11A</th><td>2.418368e-08</td><td>2.252219e-07</td><td>1.000000e-08</td><td>2.784939e-05</td><td>3.890695e-08</td><td>1.368549e-03</td><td>1.000000e-08</td><td>7.478171e-05</td><td>1.000000e-08</td><td>2.590137e-05</td><td>⋯</td><td>4.783886e-06</td><td>2.697132e-05</td><td>1.490085e-05</td><td>2.598016e-05</td><td>1.451628e-05</td><td>3.569604e-07</td><td>2.307343e-05</td><td>1.756924e-04</td><td>8.129718e-05</td><td>2.719139e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.P3.A6SW.01A</th><td>5.327950e-07</td><td>3.094013e-06</td><td>3.591916e-08</td><td>1.301609e-05</td><td>1.535664e-07</td><td>4.412129e-05</td><td>2.011031e-08</td><td>8.193661e-05</td><td>1.000000e-08</td><td>4.864593e-05</td><td>⋯</td><td>6.382070e-06</td><td>2.041353e-05</td><td>4.462938e-05</td><td>1.311606e-04</td><td>8.395353e-05</td><td>9.079317e-06</td><td>3.005215e-05</td><td>1.669662e-04</td><td>4.795567e-05</td><td>6.509430e-05</td></tr>\n",
       "\t<tr><th scope=row>TCGA.HD.A6HZ.01A</th><td>2.867783e-07</td><td>9.812338e-07</td><td>3.947893e-07</td><td>1.037214e-05</td><td>1.133375e-07</td><td>3.750284e-03</td><td>1.519284e-08</td><td>1.488054e-04</td><td>2.246281e-08</td><td>4.107929e-05</td><td>⋯</td><td>9.933341e-06</td><td>2.955015e-05</td><td>5.625813e-05</td><td>6.994455e-05</td><td>3.760442e-05</td><td>1.012045e-06</td><td>4.892394e-05</td><td>1.442509e-04</td><td>8.777987e-05</td><td>3.475095e-05</td></tr>\n",
       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "A matrix: 546 × 18234 of type dbl\n",
       "\\begin{tabular}{r|lllllllllllllllllllll}\n",
       "  & ENSG00000121410 & ENSG00000268895 & ENSG00000148584 & ENSG00000175899 & ENSG00000245105 & ENSG00000166535 & ENSG00000256069 & ENSG00000128274 & ENSG00000118017 & ENSG00000094914 & ⋯ & ENSG00000153975 & ENSG00000086827 & ENSG00000174442 & ENSG00000122952 & ENSG00000070476 & ENSG00000203995 & ENSG00000162378 & ENSG00000159840 & ENSG00000074755 & ENSG00000036549\\\\\n",
       "\\hline\n",
       "\tTCGA.BB.4224.01A & 7.112896e-07 & 1.816119e-06 & 9.364097e-08 & 3.621218e-05 & 1.604931e-07 & 1.463920e-04 & 1.728192e-08 & 8.595791e-06 & 1.113401e-07 & 4.816970e-05 & ⋯ & 1.688383e-05 & 4.109552e-05 & 4.948895e-05 & 2.232009e-04 & 6.436126e-05 & 8.086158e-06 & 4.401456e-05 & 6.694816e-05 & 4.885926e-05 & 5.912475e-05\\\\\n",
       "\tTCGA.H7.7774.01A & 1.000000e-08 & 3.055765e-07 & 1.000000e-08 & 2.999947e-05 & 9.831822e-08 & 2.973466e-03 & 1.810790e-08 & 6.325584e-05 & 1.000000e-08 & 2.424271e-05 & ⋯ & 8.324437e-06 & 2.991585e-05 & 1.176516e-05 & 2.554113e-05 & 1.917238e-05 & 1.049839e-06 & 3.525809e-05 & 2.250746e-04 & 7.796061e-05 & 2.826495e-05\\\\\n",
       "\tTCGA.CV.6943.01A & 4.240591e-07 & 2.095767e-06 & 2.250067e-08 & 1.192457e-05 & 1.112711e-08 & 6.257739e-04 & 1.563555e-08 & 5.036751e-05 & 1.174190e-08 & 4.004534e-05 & ⋯ & 8.202857e-06 & 2.796816e-05 & 2.079954e-05 & 3.936395e-05 & 1.792602e-05 & 5.487945e-08 & 1.907782e-05 & 2.410835e-04 & 8.432179e-05 & 3.307693e-05\\\\\n",
       "\tTCGA.CN.5374.01A & 5.688623e-07 & 3.710153e-06 & 7.632998e-08 & 2.041327e-05 & 4.276067e-07 & 3.069937e-04 & 8.693131e-08 & 1.711497e-04 & 8.105760e-08 & 5.006406e-05 & ⋯ & 1.198679e-05 & 2.319999e-05 & 5.350305e-05 & 1.639979e-04 & 5.114597e-05 & 5.912365e-06 & 2.957125e-05 & 1.426902e-04 & 5.812695e-05 & 8.976578e-05\\\\\n",
       "\tTCGA.CQ.6227.01A & 2.332942e-07 & 3.722853e-06 & 4.673325e-08 & 1.603208e-05 & 2.147914e-08 & 9.793864e-04 & 1.199637e-08 & 6.991207e-05 & 1.000000e-08 & 3.144777e-05 & ⋯ & 1.177592e-05 & 3.476145e-05 & 3.677868e-05 & 4.817377e-05 & 1.521257e-05 & 8.158356e-07 & 3.049380e-05 & 3.080264e-04 & 5.208826e-05 & 4.512052e-05\\\\\n",
       "\tTCGA.CV.6959.01A & 1.095189e-07 & 1.099285e-06 & 3.631508e-08 & 1.009195e-05 & 2.834081e-08 & 1.569075e-04 & 1.382765e-08 & 6.221136e-05 & 1.000000e-08 & 4.816301e-05 & ⋯ & 1.093267e-05 & 2.184035e-05 & 5.181435e-05 & 6.009834e-05 & 3.105542e-05 & 5.593178e-08 & 2.774777e-05 & 3.850048e-04 & 7.340731e-05 & 5.111540e-05\\\\\n",
       "\tTCGA.F7.A61V.01A & 6.488749e-08 & 8.260607e-07 & 2.762901e-08 & 1.661053e-05 & 6.526258e-08 & 6.957961e-04 & 5.576042e-08 & 1.660799e-04 & 1.000000e-08 & 4.595533e-05 & ⋯ & 1.254223e-05 & 3.845450e-05 & 3.403099e-05 & 8.593618e-05 & 5.133781e-05 & 7.236624e-07 & 2.285670e-05 & 1.580313e-04 & 4.675939e-05 & 4.992411e-05\\\\\n",
       "\tTCGA.CV.7413.01A & 7.152449e-07 & 4.564537e-06 & 6.039585e-08 & 1.069679e-05 & 1.346533e-08 & 2.421368e-04 & 2.089105e-08 & 9.714023e-06 & 2.237619e-08 & 7.070657e-05 & ⋯ & 1.180174e-05 & 3.282413e-05 & 3.526789e-05 & 4.109272e-05 & 3.621323e-05 & 7.663341e-08 & 2.347080e-05 & 1.550597e-04 & 6.976865e-05 & 4.175598e-05\\\\\n",
       "\tTCGA.CV.7247.01A & 6.327757e-08 & 4.347303e-07 & 1.000000e-08 & 1.534071e-05 & 1.596113e-08 & 3.955346e-04 & 1.102457e-08 & 6.344039e-05 & 1.000000e-08 & 3.543493e-05 & ⋯ & 8.242409e-06 & 2.878184e-05 & 5.191763e-05 & 9.079134e-05 & 2.787398e-05 & 1.784460e-06 & 2.728132e-05 & 1.733255e-04 & 5.414169e-05 & 6.122369e-05\\\\\n",
       "\tTCGA.CR.5249.01A & 1.204938e-07 & 1.304003e-06 & 1.000000e-08 & 1.972672e-05 & 2.524341e-07 & 1.275800e-03 & 4.587590e-08 & 3.842528e-05 & 1.000000e-08 & 4.347034e-05 & ⋯ & 1.001275e-05 & 2.092357e-05 & 4.553226e-05 & 1.109087e-04 & 4.417026e-05 & 4.727433e-06 & 4.064770e-05 & 2.483755e-04 & 9.212467e-05 & 5.698468e-05\\\\\n",
       "\tTCGA.CQ.5331.01A & 4.904080e-07 & 3.904193e-06 & 1.000000e-08 & 3.802067e-05 & 1.775944e-08 & 3.547654e-04 & 1.277123e-08 & 1.600670e-05 & 1.615829e-08 & 3.917818e-05 & ⋯ & 1.344621e-05 & 3.188899e-05 & 3.083241e-05 & 4.320952e-05 & 2.665635e-05 & 1.130897e-07 & 3.676192e-05 & 1.451680e-04 & 1.057671e-04 & 4.379419e-05\\\\\n",
       "\tTCGA.BB.8601.01A & 2.489795e-07 & 1.399710e-06 & 1.000000e-08 & 1.816752e-05 & 2.899112e-07 & 2.987224e-04 & 1.000000e-08 & 1.210167e-04 & 5.644774e-07 & 6.030766e-05 & ⋯ & 1.576661e-05 & 3.774724e-05 & 5.166895e-05 & 4.469663e-05 & 6.560713e-05 & 2.364771e-06 & 1.835305e-05 & 2.435944e-04 & 3.309973e-05 & 3.577703e-05\\\\\n",
       "\tTCGA.CV.A45W.01A & 3.341896e-07 & 1.505259e-06 & 4.588118e-08 & 1.477458e-05 & 7.129353e-07 & 7.860505e-04 & 1.965225e-08 & 6.933357e-04 & 1.000000e-08 & 7.564479e-05 & ⋯ & 1.219932e-05 & 3.475431e-05 & 4.183087e-05 & 6.151852e-05 & 5.860921e-05 & 5.503807e-06 & 2.351070e-05 & 1.689415e-04 & 5.725936e-05 & 4.625916e-05\\\\\n",
       "\tTCGA.CQ.7063.01A & 2.367013e-07 & 7.131626e-07 & 6.225785e-08 & 3.921091e-05 & 1.375956e-08 & 4.148020e-04 & 1.000000e-08 & 6.779595e-05 & 1.000000e-08 & 3.503893e-05 & ⋯ & 1.220162e-05 & 3.380328e-05 & 2.501544e-05 & 3.378373e-05 & 2.725200e-05 & 1.246665e-07 & 2.473861e-05 & 3.740954e-04 & 8.947594e-05 & 3.327431e-05\\\\\n",
       "\tTCGA.CN.5373.01A & 1.110500e-07 & 1.395054e-06 & 1.000000e-08 & 1.920272e-05 & 1.323611e-08 & 6.928735e-04 & 1.135708e-08 & 1.851542e-05 & 1.647221e-08 & 2.462936e-05 & ⋯ & 8.555410e-06 & 2.546115e-05 & 1.713736e-05 & 2.721261e-05 & 3.433372e-05 & 2.469665e-07 & 3.476788e-05 & 1.786924e-04 & 8.323724e-05 & 3.471464e-05\\\\\n",
       "\tTCGA.CV.A45T.01A & 2.311965e-07 & 2.848872e-06 & 1.000000e-08 & 1.690396e-05 & 2.381714e-08 & 5.877619e-04 & 2.650720e-08 & 3.745090e-05 & 1.000000e-08 & 4.425150e-05 & ⋯ & 9.461779e-06 & 3.674317e-05 & 2.409327e-05 & 6.648291e-05 & 2.232908e-05 & 2.283842e-07 & 2.562306e-05 & 2.979540e-04 & 5.079728e-05 & 4.287382e-05\\\\\n",
       "\tTCGA.HD.A4C1.01A & 1.133506e-07 & 8.143151e-07 & 2.952519e-08 & 9.147686e-06 & 1.848477e-08 & 1.824253e-03 & 1.000000e-08 & 2.050174e-05 & 1.531576e-08 & 3.385155e-05 & ⋯ & 1.375154e-05 & 3.996538e-05 & 4.140943e-05 & 5.820150e-05 & 3.268607e-05 & 2.484935e-07 & 4.006986e-05 & 2.865009e-04 & 8.858985e-05 & 5.208715e-05\\\\\n",
       "\tTCGA.CV.7438.11A & 2.849850e-08 & 7.780335e-07 & 1.000000e-08 & 2.511091e-05 & 4.068676e-08 & 2.306430e-03 & 3.835284e-08 & 4.069788e-05 & 1.000000e-08 & 3.582102e-05 & ⋯ & 9.986137e-06 & 3.280438e-05 & 2.201708e-05 & 2.936764e-05 & 1.825384e-05 & 7.567689e-07 & 2.819463e-05 & 2.549497e-04 & 6.962642e-05 & 4.188256e-05\\\\\n",
       "\tTCGA.CV.5444.01A & 6.977180e-08 & 9.184345e-07 & 6.541596e-08 & 1.556131e-05 & 1.387186e-08 & 3.781312e-05 & 1.701774e-08 & 2.746558e-05 & 1.532380e-08 & 5.458818e-05 & ⋯ & 1.109198e-05 & 3.447969e-05 & 3.425125e-05 & 9.014054e-05 & 4.267545e-05 & 1.694721e-07 & 3.367386e-05 & 2.155933e-04 & 6.592546e-05 & 5.377485e-05\\\\\n",
       "\tTCGA.BA.5556.01A & 1.399434e-07 & 2.567673e-06 & 2.498744e-08 & 2.442414e-05 & 1.227558e-08 & 5.432007e-04 & 1.133396e-08 & 1.018834e-04 & 1.000000e-08 & 3.673644e-05 & ⋯ & 9.226567e-06 & 3.810100e-05 & 2.496581e-05 & 4.480619e-05 & 2.826359e-05 & 9.223473e-08 & 3.382087e-05 & 3.820152e-04 & 1.145747e-04 & 3.953509e-05\\\\\n",
       "\tTCGA.P3.A6SX.01A & 5.295955e-07 & 3.703059e-06 & 4.578755e-08 & 1.191229e-05 & 1.730174e-08 & 7.153822e-05 & 2.153855e-08 & 2.714021e-05 & 2.135826e-08 & 6.914316e-05 & ⋯ & 1.010506e-05 & 2.535398e-05 & 4.251470e-05 & 7.067788e-05 & 4.601701e-05 & 2.759241e-06 & 2.782909e-05 & 1.228729e-04 & 5.473565e-05 & 6.273034e-05\\\\\n",
       "\tTCGA.CV.7242.11A & 1.447966e-07 & 3.584082e-07 & 1.842479e-08 & 1.848186e-05 & 3.684909e-08 & 1.828910e-03 & 1.385808e-08 & 1.005487e-04 & 1.000000e-08 & 3.572110e-05 & ⋯ & 9.388835e-06 & 3.151705e-05 & 2.339004e-05 & 4.435776e-05 & 1.519887e-05 & 4.655684e-07 & 2.436527e-05 & 2.302738e-04 & 6.842738e-05 & 3.747306e-05\\\\\n",
       "\tTCGA.DQ.7592.01A & 1.734400e-07 & 1.155176e-06 & 2.337038e-08 & 1.387800e-05 & 2.285894e-08 & 1.638256e-04 & 2.147076e-08 & 6.279202e-05 & 1.000000e-08 & 3.828361e-05 & ⋯ & 1.246155e-05 & 2.848459e-05 & 2.688416e-05 & 5.692476e-05 & 3.370240e-05 & 1.622993e-06 & 3.422983e-05 & 3.782780e-04 & 9.691256e-05 & 5.087237e-05\\\\\n",
       "\tTCGA.CV.6937.01A & 8.198938e-07 & 4.949553e-06 & 3.752314e-08 & 1.347374e-05 & 5.451273e-08 & 3.051719e-05 & 1.254844e-08 & 2.385506e-05 & 2.444115e-08 & 5.597677e-05 & ⋯ & 1.083458e-05 & 2.587512e-05 & 1.330435e-05 & 4.541689e-05 & 6.192550e-05 & 4.148619e-07 & 4.509375e-05 & 2.291824e-04 & 6.211986e-05 & 3.248849e-05\\\\\n",
       "\tTCGA.QK.A8ZB.01A & 2.837068e-07 & 1.510805e-06 & 5.124242e-08 & 1.222917e-05 & 2.405815e-08 & 2.458834e-04 & 2.957268e-08 & 5.870644e-05 & 1.489317e-08 & 4.413466e-05 & ⋯ & 1.438504e-05 & 4.190057e-05 & 3.191098e-05 & 3.159906e-05 & 3.714488e-05 & 7.877809e-07 & 3.547662e-05 & 1.745106e-04 & 5.561768e-05 & 4.968794e-05\\\\\n",
       "\tTCGA.CV.7432.01A & 2.393062e-07 & 1.143573e-06 & 1.000000e-08 & 1.585025e-05 & 3.435764e-08 & 6.326612e-05 & 1.229634e-08 & 9.838101e-06 & 1.000000e-08 & 5.061828e-05 & ⋯ & 7.323606e-06 & 2.347354e-05 & 2.809034e-05 & 6.897467e-05 & 2.389131e-05 & 2.754048e-06 & 1.806278e-05 & 4.240103e-04 & 6.424363e-05 & 6.081059e-05\\\\\n",
       "\tTCGA.CV.7089.01A & 8.247095e-08 & 1.471344e-06 & 2.661754e-08 & 2.982818e-05 & 1.246186e-08 & 1.587486e-03 & 1.038467e-08 & 3.785445e-05 & 1.000000e-08 & 4.696895e-05 & ⋯ & 8.723132e-06 & 2.817704e-05 & 3.291789e-05 & 6.626445e-05 & 3.203185e-05 & 3.701237e-07 & 2.995689e-05 & 3.655372e-04 & 5.180273e-05 & 3.228027e-05\\\\\n",
       "\tTCGA.CV.6939.11A & 1.000000e-08 & 1.000000e-08 & 1.000000e-08 & 1.000000e-08 & 1.000000e-08 & 1.000000e-08 & 1.000000e-08 & 3.745671e-04 & 1.000000e-08 & 1.000000e-08 & ⋯ & 1.000000e-08 & 1.000000e-08 & 1.000000e-08 & 1.000000e-08 & 1.000000e-08 & 1.000000e-08 & 1.000000e-08 & 1.000000e-08 & 1.248624e-04 & 1.000000e-08\\\\\n",
       "\tTCGA.BA.4075.01A & 8.208282e-08 & 2.119095e-06 & 1.737547e-07 & 1.032987e-06 & 2.971715e-08 & 3.250782e-06 & 1.652970e-08 & 2.960736e-05 & 1.512134e-08 & 3.313814e-05 & ⋯ & 1.279785e-05 & 2.892712e-05 & 4.382560e-05 & 4.240033e-05 & 1.784301e-05 & 8.361922e-08 & 2.020586e-05 & 2.721516e-04 & 1.280451e-05 & 5.767805e-05\\\\\n",
       "\tTCGA.T3.A92M.01A & 1.105985e-06 & 3.734028e-06 & 8.654651e-08 & 9.104048e-06 & 7.268756e-08 & 1.311396e-05 & 2.305319e-08 & 2.892186e-05 & 7.268756e-08 & 5.626057e-05 & ⋯ & 1.786274e-05 & 2.432842e-05 & 4.703002e-05 & 1.091200e-04 & 6.208567e-05 & 3.187889e-06 & 3.233632e-05 & 1.889197e-04 & 6.236092e-05 & 3.629111e-05\\\\\n",
       "\t⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋱ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮\\\\\n",
       "\tTCGA.CV.7430.01A & 5.992312e-08 & 4.316190e-07 & 4.100343e-08 & 1.423256e-05 & 7.614986e-08 & 8.471157e-04 & 1.000000e-08 & 6.978670e-05 & 2.042654e-08 & 3.853621e-05 & ⋯ & 1.264069e-05 & 3.960967e-05 & 3.717462e-05 & 4.984853e-05 & 4.044724e-05 & 3.036183e-06 & 3.712124e-05 & 2.335524e-04 & 8.635110e-05 & 5.497010e-05\\\\\n",
       "\tTCGA.D6.A74Q.01A & 5.906717e-07 & 3.218203e-06 & 1.000000e-08 & 5.075967e-06 & 4.651282e-08 & 2.866994e-04 & 2.156418e-08 & 1.291496e-04 & 1.000000e-08 & 5.972753e-05 & ⋯ & 1.532419e-05 & 2.926941e-05 & 3.902315e-05 & 1.499300e-04 & 3.898235e-05 & 3.639974e-06 & 1.956117e-05 & 3.995424e-04 & 3.777732e-05 & 3.815455e-05\\\\\n",
       "\tTCGA.CV.7255.01A & 1.000000e-08 & 4.927327e-08 & 2.262154e-08 & 7.523477e-06 & 3.039731e-08 & 2.023672e-04 & 1.129596e-08 & 9.066132e-05 & 1.000000e-08 & 4.400175e-05 & ⋯ & 1.139795e-05 & 3.899337e-05 & 3.734795e-05 & 4.424697e-05 & 4.001470e-05 & 7.762513e-07 & 4.356174e-05 & 3.151445e-04 & 8.641293e-05 & 5.587264e-05\\\\\n",
       "\tTCGA.CQ.6223.01A & 1.357241e-07 & 8.593188e-07 & 4.068498e-08 & 2.909884e-05 & 2.524518e-08 & 5.389829e-04 & 2.076894e-08 & 1.237306e-05 & 1.000000e-08 & 2.535573e-05 & ⋯ & 9.995334e-06 & 2.695394e-05 & 2.243365e-05 & 4.489370e-05 & 4.750166e-05 & 2.506792e-07 & 2.826659e-05 & 3.110916e-04 & 5.003158e-05 & 3.253504e-05\\\\\n",
       "\tTCGA.CV.A460.01A & 1.563773e-07 & 1.277916e-06 & 1.000000e-08 & 9.654251e-06 & 5.704522e-07 & 4.379689e-04 & 1.035673e-07 & 6.906425e-05 & 3.664289e-08 & 6.853885e-05 & ⋯ & 1.474273e-05 & 2.165545e-05 & 3.136948e-05 & 5.283001e-05 & 4.540727e-05 & 2.012023e-06 & 3.496452e-05 & 1.878741e-04 & 5.432899e-05 & 5.297623e-05\\\\\n",
       "\tTCGA.CV.7261.01A & 1.665030e-07 & 3.901885e-07 & 2.906323e-08 & 1.132787e-05 & 3.359198e-07 & 2.860075e-04 & 1.230604e-08 & 1.498001e-04 & 1.618909e-07 & 4.263600e-05 & ⋯ & 1.691570e-05 & 5.612231e-05 & 5.952034e-05 & 6.640847e-05 & 6.396268e-05 & 3.700491e-07 & 2.714467e-05 & 3.126007e-04 & 6.837413e-05 & 4.239125e-05\\\\\n",
       "\tTCGA.CN.4736.01A & 2.406184e-07 & 7.075260e-07 & 5.304101e-08 & 3.287152e-05 & 1.261736e-08 & 2.536685e-04 & 2.366843e-08 & 1.693020e-05 & 1.959698e-08 & 3.909167e-05 & ⋯ & 8.256569e-06 & 3.579729e-05 & 2.999039e-05 & 5.166633e-05 & 3.844707e-05 & 3.312000e-08 & 5.097928e-05 & 2.352842e-04 & 9.728805e-05 & 5.721484e-05\\\\\n",
       "\tTCGA.CR.7404.01A & 2.021346e-07 & 1.770215e-06 & 2.311015e-08 & 2.722137e-05 & 1.746742e-07 & 2.898410e-04 & 1.593500e-08 & 5.946127e-05 & 2.311015e-08 & 4.793213e-05 & ⋯ & 6.406515e-06 & 2.989495e-05 & 5.368581e-05 & 1.027929e-04 & 8.676051e-05 & 8.699464e-06 & 3.976442e-05 & 2.060475e-04 & 1.076988e-04 & 6.827457e-05\\\\\n",
       "\tTCGA.UF.A719.01A & 2.287460e-07 & 1.194490e-06 & 4.452210e-08 & 1.156790e-05 & 1.795083e-07 & 6.265976e-04 & 1.000000e-08 & 1.573143e-04 & 1.014756e-07 & 3.996623e-05 & ⋯ & 2.240991e-05 & 3.083760e-05 & 4.057689e-05 & 8.318972e-05 & 5.420023e-05 & 5.502195e-06 & 2.682675e-05 & 2.526194e-04 & 7.717047e-05 & 3.166247e-05\\\\\n",
       "\tTCGA.CV.7236.01A & 1.415668e-07 & 3.236452e-06 & 2.480716e-08 & 1.586300e-05 & 1.113176e-08 & 6.024393e-05 & 1.000000e-08 & 3.476194e-05 & 1.000000e-08 & 3.685805e-05 & ⋯ & 1.254780e-05 & 4.125521e-05 & 2.973344e-05 & 5.050591e-05 & 3.414947e-05 & 7.139785e-08 & 2.926980e-05 & 3.100679e-04 & 1.012570e-04 & 5.451327e-05\\\\\n",
       "\tTCGA.CV.6951.01A & 4.044799e-07 & 4.174614e-06 & 1.000000e-08 & 1.927283e-05 & 2.988900e-07 & 6.876290e-04 & 2.264854e-07 & 1.099859e-04 & 1.950685e-07 & 3.673897e-05 & ⋯ & 9.771089e-06 & 3.152647e-05 & 1.785293e-05 & 2.334205e-05 & 4.515652e-05 & 8.247592e-07 & 2.676806e-05 & 2.145656e-04 & 1.010798e-04 & 6.089078e-05\\\\\n",
       "\tTCGA.CN.4728.01A & 4.336213e-07 & 2.660096e-06 & 6.812478e-08 & 1.024489e-05 & 3.758464e-08 & 1.189281e-03 & 2.247877e-08 & 8.836066e-05 & 1.919488e-08 & 3.754712e-05 & ⋯ & 8.126781e-06 & 2.912493e-05 & 3.314047e-05 & 7.982748e-05 & 5.703698e-05 & 7.166923e-07 & 2.742946e-05 & 2.034198e-04 & 6.571169e-05 & 4.317406e-05\\\\\n",
       "\tTCGA.CV.7090.01A & 1.294972e-07 & 6.863691e-07 & 1.000000e-08 & 1.133545e-05 & 1.345653e-08 & 2.727092e-05 & 1.185171e-08 & 5.001848e-06 & 1.333308e-08 & 3.332022e-05 & ⋯ & 8.960687e-06 & 2.090016e-05 & 4.915027e-05 & 4.212438e-05 & 3.918176e-05 & 1.000000e-08 & 3.281396e-05 & 4.687791e-04 & 6.574890e-05 & 3.779211e-05\\\\\n",
       "\tTCGA.CV.5979.01A & 2.645943e-08 & 3.037834e-08 & 3.028037e-08 & 2.998465e-06 & 2.743916e-08 & 2.418532e-04 & 1.558445e-08 & 5.951702e-05 & 1.000000e-08 & 4.779614e-05 & ⋯ & 8.988522e-06 & 1.272109e-05 & 3.512541e-05 & 3.674373e-05 & 3.024813e-05 & 3.771041e-07 & 3.516098e-05 & 4.204467e-04 & 4.820018e-05 & 4.464063e-05\\\\\n",
       "\tTCGA.CQ.7069.01A & 1.744712e-07 & 1.541398e-06 & 8.156685e-08 & 8.556673e-06 & 1.490365e-08 & 1.430076e-04 & 1.662656e-08 & 1.105873e-05 & 1.000000e-08 & 2.536097e-05 & ⋯ & 1.264765e-05 & 2.414579e-05 & 3.010678e-05 & 2.258006e-05 & 3.145634e-05 & 3.153519e-07 & 2.720858e-05 & 4.259971e-04 & 4.564460e-05 & 2.595895e-05\\\\\n",
       "\tTCGA.CN.4733.01A & 8.847056e-08 & 1.419331e-06 & 2.457310e-08 & 1.331480e-05 & 1.313882e-08 & 3.572621e-05 & 1.022420e-08 & 6.077850e-05 & 1.560504e-08 & 5.411276e-05 & ⋯ & 1.382351e-05 & 4.042234e-05 & 2.912594e-05 & 9.503942e-05 & 2.637745e-05 & 8.398653e-08 & 2.558109e-05 & 3.552050e-04 & 8.559336e-05 & 4.522407e-05\\\\\n",
       "\tTCGA.CR.7390.01A & 7.033687e-08 & 2.668394e-07 & 1.000000e-08 & 6.803786e-06 & 7.595381e-08 & 1.617098e-03 & 1.154013e-08 & 9.424985e-05 & 4.234274e-08 & 2.279786e-05 & ⋯ & 8.722879e-06 & 3.009699e-05 & 4.232997e-05 & 6.324648e-05 & 4.315285e-05 & 2.235216e-06 & 3.633153e-05 & 2.488503e-04 & 4.194766e-05 & 4.857112e-05\\\\\n",
       "\tTCGA.CV.A45X.01A & 6.251957e-08 & 3.740855e-07 & 8.813362e-08 & 1.553685e-05 & 1.721068e-08 & 9.506332e-04 & 4.174851e-08 & 6.365759e-05 & 1.000000e-08 & 2.879255e-05 & ⋯ & 1.206260e-05 & 3.156587e-05 & 2.067817e-05 & 3.839815e-05 & 4.571709e-05 & 1.516817e-06 & 4.216944e-05 & 1.323282e-04 & 5.792434e-05 & 4.926701e-05\\\\\n",
       "\tTCGA.IQ.A6SH.01A & 1.096632e-07 & 1.939058e-06 & 1.000000e-08 & 1.250559e-05 & 2.979841e-08 & 2.678809e-04 & 2.185667e-08 & 1.076140e-04 & 1.000000e-08 & 6.607560e-05 & ⋯ & 1.609883e-05 & 3.553158e-05 & 2.347749e-05 & 3.265119e-05 & 2.525442e-05 & 4.322541e-07 & 1.931993e-05 & 2.521374e-04 & 3.989081e-05 & 3.527331e-05\\\\\n",
       "\tTCGA.CV.6962.11A & 5.200397e-08 & 2.035130e-07 & 1.000000e-08 & 2.857071e-05 & 7.698528e-08 & 4.107892e-03 & 1.000000e-08 & 1.346954e-04 & 1.000000e-08 & 2.744051e-05 & ⋯ & 5.120336e-06 & 2.686948e-05 & 1.576429e-05 & 2.542071e-05 & 1.756936e-05 & 1.320524e-06 & 2.958898e-05 & 1.754682e-04 & 7.299102e-05 & 2.940011e-05\\\\\n",
       "\tTCGA.CV.6960.11A & 3.402361e-08 & 2.908119e-07 & 2.436819e-08 & 3.046435e-05 & 2.873612e-08 & 2.513120e-03 & 1.172418e-08 & 6.795268e-05 & 1.000000e-08 & 3.238705e-05 & ⋯ & 9.303920e-06 & 2.819361e-05 & 2.395568e-05 & 3.186382e-05 & 2.138331e-05 & 3.633425e-07 & 3.495539e-05 & 3.200481e-04 & 9.644285e-05 & 4.983267e-05\\\\\n",
       "\tTCGA.CV.A464.01A & 1.817166e-07 & 2.650198e-06 & 4.178302e-08 & 1.272615e-05 & 1.353145e-08 & 3.495293e-05 & 2.839295e-08 & 1.456133e-05 & 1.161858e-08 & 6.225308e-05 & ⋯ & 1.449747e-05 & 3.969405e-05 & 4.049480e-05 & 5.752197e-05 & 2.347514e-05 & 2.336583e-07 & 2.786002e-05 & 2.649415e-04 & 4.804563e-05 & 3.662360e-05\\\\\n",
       "\tTCGA.C9.A47Z.01A & 1.384600e-07 & 1.939077e-06 & 1.000000e-08 & 3.848765e-05 & 1.478949e-07 & 7.352721e-04 & 1.642818e-08 & 1.322168e-05 & 1.000000e-08 & 4.057763e-05 & ⋯ & 1.064781e-05 & 3.285023e-05 & 3.109866e-05 & 2.854366e-05 & 4.843298e-05 & 2.555151e-07 & 3.217569e-05 & 1.967548e-04 & 7.272145e-05 & 4.140324e-05\\\\\n",
       "\tTCGA.CN.6010.01A & 1.632860e-07 & 9.065136e-07 & 2.032884e-08 & 1.705648e-05 & 3.956101e-07 & 9.547081e-05 & 1.194601e-08 & 2.303115e-04 & 3.718089e-07 & 4.849059e-05 & ⋯ & 8.693862e-06 & 3.882429e-05 & 7.222762e-05 & 8.577996e-05 & 3.221383e-05 & 1.778063e-07 & 2.927056e-05 & 1.852030e-04 & 9.048408e-05 & 5.164957e-05\\\\\n",
       "\tTCGA.WA.A7GZ.11A & 2.786106e-07 & 1.206237e-06 & 1.425476e-07 & 9.061288e-06 & 1.184732e-06 & 3.604722e-03 & 6.955339e-08 & 3.738554e-05 & 4.143095e-08 & 1.680033e-05 & ⋯ & 1.017895e-05 & 3.332661e-05 & 1.974347e-05 & 2.994902e-05 & 1.621741e-05 & 9.469319e-07 & 1.216002e-04 & 7.325901e-05 & 5.763307e-05 & 4.442421e-05\\\\\n",
       "\tTCGA.CV.7235.01A & 5.456606e-07 & 2.264343e-06 & 1.000000e-08 & 1.476062e-05 & 1.830712e-08 & 6.823170e-06 & 1.044502e-08 & 2.685593e-05 & 1.000000e-08 & 2.724191e-05 & ⋯ & 7.464746e-06 & 1.738329e-05 & 5.189980e-05 & 3.644026e-05 & 2.241993e-05 & 4.246480e-06 & 3.151444e-05 & 3.181916e-04 & 7.806484e-05 & 5.641338e-05\\\\\n",
       "\tTCGA.CX.7086.01A & 1.147891e-07 & 1.070028e-06 & 2.687282e-08 & 2.155978e-05 & 9.007191e-08 & 9.884022e-04 & 2.361666e-08 & 1.391071e-04 & 1.000000e-08 & 5.256944e-05 & ⋯ & 1.074008e-05 & 2.238995e-05 & 3.763070e-05 & 4.660105e-05 & 5.250173e-05 & 8.732214e-06 & 3.691013e-05 & 2.525940e-04 & 5.755536e-05 & 4.827834e-05\\\\\n",
       "\tTCGA.CV.6935.11A & 2.418368e-08 & 2.252219e-07 & 1.000000e-08 & 2.784939e-05 & 3.890695e-08 & 1.368549e-03 & 1.000000e-08 & 7.478171e-05 & 1.000000e-08 & 2.590137e-05 & ⋯ & 4.783886e-06 & 2.697132e-05 & 1.490085e-05 & 2.598016e-05 & 1.451628e-05 & 3.569604e-07 & 2.307343e-05 & 1.756924e-04 & 8.129718e-05 & 2.719139e-05\\\\\n",
       "\tTCGA.P3.A6SW.01A & 5.327950e-07 & 3.094013e-06 & 3.591916e-08 & 1.301609e-05 & 1.535664e-07 & 4.412129e-05 & 2.011031e-08 & 8.193661e-05 & 1.000000e-08 & 4.864593e-05 & ⋯ & 6.382070e-06 & 2.041353e-05 & 4.462938e-05 & 1.311606e-04 & 8.395353e-05 & 9.079317e-06 & 3.005215e-05 & 1.669662e-04 & 4.795567e-05 & 6.509430e-05\\\\\n",
       "\tTCGA.HD.A6HZ.01A & 2.867783e-07 & 9.812338e-07 & 3.947893e-07 & 1.037214e-05 & 1.133375e-07 & 3.750284e-03 & 1.519284e-08 & 1.488054e-04 & 2.246281e-08 & 4.107929e-05 & ⋯ & 9.933341e-06 & 2.955015e-05 & 5.625813e-05 & 6.994455e-05 & 3.760442e-05 & 1.012045e-06 & 4.892394e-05 & 1.442509e-04 & 8.777987e-05 & 3.475095e-05\\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "A matrix: 546 × 18234 of type dbl\n",
       "\n",
       "| <!--/--> | ENSG00000121410 | ENSG00000268895 | ENSG00000148584 | ENSG00000175899 | ENSG00000245105 | ENSG00000166535 | ENSG00000256069 | ENSG00000128274 | ENSG00000118017 | ENSG00000094914 | ⋯ | ENSG00000153975 | ENSG00000086827 | ENSG00000174442 | ENSG00000122952 | ENSG00000070476 | ENSG00000203995 | ENSG00000162378 | ENSG00000159840 | ENSG00000074755 | ENSG00000036549 |\n",
       "|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|\n",
       "| TCGA.BB.4224.01A | 7.112896e-07 | 1.816119e-06 | 9.364097e-08 | 3.621218e-05 | 1.604931e-07 | 1.463920e-04 | 1.728192e-08 | 8.595791e-06 | 1.113401e-07 | 4.816970e-05 | ⋯ | 1.688383e-05 | 4.109552e-05 | 4.948895e-05 | 2.232009e-04 | 6.436126e-05 | 8.086158e-06 | 4.401456e-05 | 6.694816e-05 | 4.885926e-05 | 5.912475e-05 |\n",
       "| TCGA.H7.7774.01A | 1.000000e-08 | 3.055765e-07 | 1.000000e-08 | 2.999947e-05 | 9.831822e-08 | 2.973466e-03 | 1.810790e-08 | 6.325584e-05 | 1.000000e-08 | 2.424271e-05 | ⋯ | 8.324437e-06 | 2.991585e-05 | 1.176516e-05 | 2.554113e-05 | 1.917238e-05 | 1.049839e-06 | 3.525809e-05 | 2.250746e-04 | 7.796061e-05 | 2.826495e-05 |\n",
       "| TCGA.CV.6943.01A | 4.240591e-07 | 2.095767e-06 | 2.250067e-08 | 1.192457e-05 | 1.112711e-08 | 6.257739e-04 | 1.563555e-08 | 5.036751e-05 | 1.174190e-08 | 4.004534e-05 | ⋯ | 8.202857e-06 | 2.796816e-05 | 2.079954e-05 | 3.936395e-05 | 1.792602e-05 | 5.487945e-08 | 1.907782e-05 | 2.410835e-04 | 8.432179e-05 | 3.307693e-05 |\n",
       "| TCGA.CN.5374.01A | 5.688623e-07 | 3.710153e-06 | 7.632998e-08 | 2.041327e-05 | 4.276067e-07 | 3.069937e-04 | 8.693131e-08 | 1.711497e-04 | 8.105760e-08 | 5.006406e-05 | ⋯ | 1.198679e-05 | 2.319999e-05 | 5.350305e-05 | 1.639979e-04 | 5.114597e-05 | 5.912365e-06 | 2.957125e-05 | 1.426902e-04 | 5.812695e-05 | 8.976578e-05 |\n",
       "| TCGA.CQ.6227.01A | 2.332942e-07 | 3.722853e-06 | 4.673325e-08 | 1.603208e-05 | 2.147914e-08 | 9.793864e-04 | 1.199637e-08 | 6.991207e-05 | 1.000000e-08 | 3.144777e-05 | ⋯ | 1.177592e-05 | 3.476145e-05 | 3.677868e-05 | 4.817377e-05 | 1.521257e-05 | 8.158356e-07 | 3.049380e-05 | 3.080264e-04 | 5.208826e-05 | 4.512052e-05 |\n",
       "| TCGA.CV.6959.01A | 1.095189e-07 | 1.099285e-06 | 3.631508e-08 | 1.009195e-05 | 2.834081e-08 | 1.569075e-04 | 1.382765e-08 | 6.221136e-05 | 1.000000e-08 | 4.816301e-05 | ⋯ | 1.093267e-05 | 2.184035e-05 | 5.181435e-05 | 6.009834e-05 | 3.105542e-05 | 5.593178e-08 | 2.774777e-05 | 3.850048e-04 | 7.340731e-05 | 5.111540e-05 |\n",
       "| TCGA.F7.A61V.01A | 6.488749e-08 | 8.260607e-07 | 2.762901e-08 | 1.661053e-05 | 6.526258e-08 | 6.957961e-04 | 5.576042e-08 | 1.660799e-04 | 1.000000e-08 | 4.595533e-05 | ⋯ | 1.254223e-05 | 3.845450e-05 | 3.403099e-05 | 8.593618e-05 | 5.133781e-05 | 7.236624e-07 | 2.285670e-05 | 1.580313e-04 | 4.675939e-05 | 4.992411e-05 |\n",
       "| TCGA.CV.7413.01A | 7.152449e-07 | 4.564537e-06 | 6.039585e-08 | 1.069679e-05 | 1.346533e-08 | 2.421368e-04 | 2.089105e-08 | 9.714023e-06 | 2.237619e-08 | 7.070657e-05 | ⋯ | 1.180174e-05 | 3.282413e-05 | 3.526789e-05 | 4.109272e-05 | 3.621323e-05 | 7.663341e-08 | 2.347080e-05 | 1.550597e-04 | 6.976865e-05 | 4.175598e-05 |\n",
       "| TCGA.CV.7247.01A | 6.327757e-08 | 4.347303e-07 | 1.000000e-08 | 1.534071e-05 | 1.596113e-08 | 3.955346e-04 | 1.102457e-08 | 6.344039e-05 | 1.000000e-08 | 3.543493e-05 | ⋯ | 8.242409e-06 | 2.878184e-05 | 5.191763e-05 | 9.079134e-05 | 2.787398e-05 | 1.784460e-06 | 2.728132e-05 | 1.733255e-04 | 5.414169e-05 | 6.122369e-05 |\n",
       "| TCGA.CR.5249.01A | 1.204938e-07 | 1.304003e-06 | 1.000000e-08 | 1.972672e-05 | 2.524341e-07 | 1.275800e-03 | 4.587590e-08 | 3.842528e-05 | 1.000000e-08 | 4.347034e-05 | ⋯ | 1.001275e-05 | 2.092357e-05 | 4.553226e-05 | 1.109087e-04 | 4.417026e-05 | 4.727433e-06 | 4.064770e-05 | 2.483755e-04 | 9.212467e-05 | 5.698468e-05 |\n",
       "| TCGA.CQ.5331.01A | 4.904080e-07 | 3.904193e-06 | 1.000000e-08 | 3.802067e-05 | 1.775944e-08 | 3.547654e-04 | 1.277123e-08 | 1.600670e-05 | 1.615829e-08 | 3.917818e-05 | ⋯ | 1.344621e-05 | 3.188899e-05 | 3.083241e-05 | 4.320952e-05 | 2.665635e-05 | 1.130897e-07 | 3.676192e-05 | 1.451680e-04 | 1.057671e-04 | 4.379419e-05 |\n",
       "| TCGA.BB.8601.01A | 2.489795e-07 | 1.399710e-06 | 1.000000e-08 | 1.816752e-05 | 2.899112e-07 | 2.987224e-04 | 1.000000e-08 | 1.210167e-04 | 5.644774e-07 | 6.030766e-05 | ⋯ | 1.576661e-05 | 3.774724e-05 | 5.166895e-05 | 4.469663e-05 | 6.560713e-05 | 2.364771e-06 | 1.835305e-05 | 2.435944e-04 | 3.309973e-05 | 3.577703e-05 |\n",
       "| TCGA.CV.A45W.01A | 3.341896e-07 | 1.505259e-06 | 4.588118e-08 | 1.477458e-05 | 7.129353e-07 | 7.860505e-04 | 1.965225e-08 | 6.933357e-04 | 1.000000e-08 | 7.564479e-05 | ⋯ | 1.219932e-05 | 3.475431e-05 | 4.183087e-05 | 6.151852e-05 | 5.860921e-05 | 5.503807e-06 | 2.351070e-05 | 1.689415e-04 | 5.725936e-05 | 4.625916e-05 |\n",
       "| TCGA.CQ.7063.01A | 2.367013e-07 | 7.131626e-07 | 6.225785e-08 | 3.921091e-05 | 1.375956e-08 | 4.148020e-04 | 1.000000e-08 | 6.779595e-05 | 1.000000e-08 | 3.503893e-05 | ⋯ | 1.220162e-05 | 3.380328e-05 | 2.501544e-05 | 3.378373e-05 | 2.725200e-05 | 1.246665e-07 | 2.473861e-05 | 3.740954e-04 | 8.947594e-05 | 3.327431e-05 |\n",
       "| TCGA.CN.5373.01A | 1.110500e-07 | 1.395054e-06 | 1.000000e-08 | 1.920272e-05 | 1.323611e-08 | 6.928735e-04 | 1.135708e-08 | 1.851542e-05 | 1.647221e-08 | 2.462936e-05 | ⋯ | 8.555410e-06 | 2.546115e-05 | 1.713736e-05 | 2.721261e-05 | 3.433372e-05 | 2.469665e-07 | 3.476788e-05 | 1.786924e-04 | 8.323724e-05 | 3.471464e-05 |\n",
       "| TCGA.CV.A45T.01A | 2.311965e-07 | 2.848872e-06 | 1.000000e-08 | 1.690396e-05 | 2.381714e-08 | 5.877619e-04 | 2.650720e-08 | 3.745090e-05 | 1.000000e-08 | 4.425150e-05 | ⋯ | 9.461779e-06 | 3.674317e-05 | 2.409327e-05 | 6.648291e-05 | 2.232908e-05 | 2.283842e-07 | 2.562306e-05 | 2.979540e-04 | 5.079728e-05 | 4.287382e-05 |\n",
       "| TCGA.HD.A4C1.01A | 1.133506e-07 | 8.143151e-07 | 2.952519e-08 | 9.147686e-06 | 1.848477e-08 | 1.824253e-03 | 1.000000e-08 | 2.050174e-05 | 1.531576e-08 | 3.385155e-05 | ⋯ | 1.375154e-05 | 3.996538e-05 | 4.140943e-05 | 5.820150e-05 | 3.268607e-05 | 2.484935e-07 | 4.006986e-05 | 2.865009e-04 | 8.858985e-05 | 5.208715e-05 |\n",
       "| TCGA.CV.7438.11A | 2.849850e-08 | 7.780335e-07 | 1.000000e-08 | 2.511091e-05 | 4.068676e-08 | 2.306430e-03 | 3.835284e-08 | 4.069788e-05 | 1.000000e-08 | 3.582102e-05 | ⋯ | 9.986137e-06 | 3.280438e-05 | 2.201708e-05 | 2.936764e-05 | 1.825384e-05 | 7.567689e-07 | 2.819463e-05 | 2.549497e-04 | 6.962642e-05 | 4.188256e-05 |\n",
       "| TCGA.CV.5444.01A | 6.977180e-08 | 9.184345e-07 | 6.541596e-08 | 1.556131e-05 | 1.387186e-08 | 3.781312e-05 | 1.701774e-08 | 2.746558e-05 | 1.532380e-08 | 5.458818e-05 | ⋯ | 1.109198e-05 | 3.447969e-05 | 3.425125e-05 | 9.014054e-05 | 4.267545e-05 | 1.694721e-07 | 3.367386e-05 | 2.155933e-04 | 6.592546e-05 | 5.377485e-05 |\n",
       "| TCGA.BA.5556.01A | 1.399434e-07 | 2.567673e-06 | 2.498744e-08 | 2.442414e-05 | 1.227558e-08 | 5.432007e-04 | 1.133396e-08 | 1.018834e-04 | 1.000000e-08 | 3.673644e-05 | ⋯ | 9.226567e-06 | 3.810100e-05 | 2.496581e-05 | 4.480619e-05 | 2.826359e-05 | 9.223473e-08 | 3.382087e-05 | 3.820152e-04 | 1.145747e-04 | 3.953509e-05 |\n",
       "| TCGA.P3.A6SX.01A | 5.295955e-07 | 3.703059e-06 | 4.578755e-08 | 1.191229e-05 | 1.730174e-08 | 7.153822e-05 | 2.153855e-08 | 2.714021e-05 | 2.135826e-08 | 6.914316e-05 | ⋯ | 1.010506e-05 | 2.535398e-05 | 4.251470e-05 | 7.067788e-05 | 4.601701e-05 | 2.759241e-06 | 2.782909e-05 | 1.228729e-04 | 5.473565e-05 | 6.273034e-05 |\n",
       "| TCGA.CV.7242.11A | 1.447966e-07 | 3.584082e-07 | 1.842479e-08 | 1.848186e-05 | 3.684909e-08 | 1.828910e-03 | 1.385808e-08 | 1.005487e-04 | 1.000000e-08 | 3.572110e-05 | ⋯ | 9.388835e-06 | 3.151705e-05 | 2.339004e-05 | 4.435776e-05 | 1.519887e-05 | 4.655684e-07 | 2.436527e-05 | 2.302738e-04 | 6.842738e-05 | 3.747306e-05 |\n",
       "| TCGA.DQ.7592.01A | 1.734400e-07 | 1.155176e-06 | 2.337038e-08 | 1.387800e-05 | 2.285894e-08 | 1.638256e-04 | 2.147076e-08 | 6.279202e-05 | 1.000000e-08 | 3.828361e-05 | ⋯ | 1.246155e-05 | 2.848459e-05 | 2.688416e-05 | 5.692476e-05 | 3.370240e-05 | 1.622993e-06 | 3.422983e-05 | 3.782780e-04 | 9.691256e-05 | 5.087237e-05 |\n",
       "| TCGA.CV.6937.01A | 8.198938e-07 | 4.949553e-06 | 3.752314e-08 | 1.347374e-05 | 5.451273e-08 | 3.051719e-05 | 1.254844e-08 | 2.385506e-05 | 2.444115e-08 | 5.597677e-05 | ⋯ | 1.083458e-05 | 2.587512e-05 | 1.330435e-05 | 4.541689e-05 | 6.192550e-05 | 4.148619e-07 | 4.509375e-05 | 2.291824e-04 | 6.211986e-05 | 3.248849e-05 |\n",
       "| TCGA.QK.A8ZB.01A | 2.837068e-07 | 1.510805e-06 | 5.124242e-08 | 1.222917e-05 | 2.405815e-08 | 2.458834e-04 | 2.957268e-08 | 5.870644e-05 | 1.489317e-08 | 4.413466e-05 | ⋯ | 1.438504e-05 | 4.190057e-05 | 3.191098e-05 | 3.159906e-05 | 3.714488e-05 | 7.877809e-07 | 3.547662e-05 | 1.745106e-04 | 5.561768e-05 | 4.968794e-05 |\n",
       "| TCGA.CV.7432.01A | 2.393062e-07 | 1.143573e-06 | 1.000000e-08 | 1.585025e-05 | 3.435764e-08 | 6.326612e-05 | 1.229634e-08 | 9.838101e-06 | 1.000000e-08 | 5.061828e-05 | ⋯ | 7.323606e-06 | 2.347354e-05 | 2.809034e-05 | 6.897467e-05 | 2.389131e-05 | 2.754048e-06 | 1.806278e-05 | 4.240103e-04 | 6.424363e-05 | 6.081059e-05 |\n",
       "| TCGA.CV.7089.01A | 8.247095e-08 | 1.471344e-06 | 2.661754e-08 | 2.982818e-05 | 1.246186e-08 | 1.587486e-03 | 1.038467e-08 | 3.785445e-05 | 1.000000e-08 | 4.696895e-05 | ⋯ | 8.723132e-06 | 2.817704e-05 | 3.291789e-05 | 6.626445e-05 | 3.203185e-05 | 3.701237e-07 | 2.995689e-05 | 3.655372e-04 | 5.180273e-05 | 3.228027e-05 |\n",
       "| TCGA.CV.6939.11A | 1.000000e-08 | 1.000000e-08 | 1.000000e-08 | 1.000000e-08 | 1.000000e-08 | 1.000000e-08 | 1.000000e-08 | 3.745671e-04 | 1.000000e-08 | 1.000000e-08 | ⋯ | 1.000000e-08 | 1.000000e-08 | 1.000000e-08 | 1.000000e-08 | 1.000000e-08 | 1.000000e-08 | 1.000000e-08 | 1.000000e-08 | 1.248624e-04 | 1.000000e-08 |\n",
       "| TCGA.BA.4075.01A | 8.208282e-08 | 2.119095e-06 | 1.737547e-07 | 1.032987e-06 | 2.971715e-08 | 3.250782e-06 | 1.652970e-08 | 2.960736e-05 | 1.512134e-08 | 3.313814e-05 | ⋯ | 1.279785e-05 | 2.892712e-05 | 4.382560e-05 | 4.240033e-05 | 1.784301e-05 | 8.361922e-08 | 2.020586e-05 | 2.721516e-04 | 1.280451e-05 | 5.767805e-05 |\n",
       "| TCGA.T3.A92M.01A | 1.105985e-06 | 3.734028e-06 | 8.654651e-08 | 9.104048e-06 | 7.268756e-08 | 1.311396e-05 | 2.305319e-08 | 2.892186e-05 | 7.268756e-08 | 5.626057e-05 | ⋯ | 1.786274e-05 | 2.432842e-05 | 4.703002e-05 | 1.091200e-04 | 6.208567e-05 | 3.187889e-06 | 3.233632e-05 | 1.889197e-04 | 6.236092e-05 | 3.629111e-05 |\n",
       "| ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋱ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ |\n",
       "| TCGA.CV.7430.01A | 5.992312e-08 | 4.316190e-07 | 4.100343e-08 | 1.423256e-05 | 7.614986e-08 | 8.471157e-04 | 1.000000e-08 | 6.978670e-05 | 2.042654e-08 | 3.853621e-05 | ⋯ | 1.264069e-05 | 3.960967e-05 | 3.717462e-05 | 4.984853e-05 | 4.044724e-05 | 3.036183e-06 | 3.712124e-05 | 2.335524e-04 | 8.635110e-05 | 5.497010e-05 |\n",
       "| TCGA.D6.A74Q.01A | 5.906717e-07 | 3.218203e-06 | 1.000000e-08 | 5.075967e-06 | 4.651282e-08 | 2.866994e-04 | 2.156418e-08 | 1.291496e-04 | 1.000000e-08 | 5.972753e-05 | ⋯ | 1.532419e-05 | 2.926941e-05 | 3.902315e-05 | 1.499300e-04 | 3.898235e-05 | 3.639974e-06 | 1.956117e-05 | 3.995424e-04 | 3.777732e-05 | 3.815455e-05 |\n",
       "| TCGA.CV.7255.01A | 1.000000e-08 | 4.927327e-08 | 2.262154e-08 | 7.523477e-06 | 3.039731e-08 | 2.023672e-04 | 1.129596e-08 | 9.066132e-05 | 1.000000e-08 | 4.400175e-05 | ⋯ | 1.139795e-05 | 3.899337e-05 | 3.734795e-05 | 4.424697e-05 | 4.001470e-05 | 7.762513e-07 | 4.356174e-05 | 3.151445e-04 | 8.641293e-05 | 5.587264e-05 |\n",
       "| TCGA.CQ.6223.01A | 1.357241e-07 | 8.593188e-07 | 4.068498e-08 | 2.909884e-05 | 2.524518e-08 | 5.389829e-04 | 2.076894e-08 | 1.237306e-05 | 1.000000e-08 | 2.535573e-05 | ⋯ | 9.995334e-06 | 2.695394e-05 | 2.243365e-05 | 4.489370e-05 | 4.750166e-05 | 2.506792e-07 | 2.826659e-05 | 3.110916e-04 | 5.003158e-05 | 3.253504e-05 |\n",
       "| TCGA.CV.A460.01A | 1.563773e-07 | 1.277916e-06 | 1.000000e-08 | 9.654251e-06 | 5.704522e-07 | 4.379689e-04 | 1.035673e-07 | 6.906425e-05 | 3.664289e-08 | 6.853885e-05 | ⋯ | 1.474273e-05 | 2.165545e-05 | 3.136948e-05 | 5.283001e-05 | 4.540727e-05 | 2.012023e-06 | 3.496452e-05 | 1.878741e-04 | 5.432899e-05 | 5.297623e-05 |\n",
       "| TCGA.CV.7261.01A | 1.665030e-07 | 3.901885e-07 | 2.906323e-08 | 1.132787e-05 | 3.359198e-07 | 2.860075e-04 | 1.230604e-08 | 1.498001e-04 | 1.618909e-07 | 4.263600e-05 | ⋯ | 1.691570e-05 | 5.612231e-05 | 5.952034e-05 | 6.640847e-05 | 6.396268e-05 | 3.700491e-07 | 2.714467e-05 | 3.126007e-04 | 6.837413e-05 | 4.239125e-05 |\n",
       "| TCGA.CN.4736.01A | 2.406184e-07 | 7.075260e-07 | 5.304101e-08 | 3.287152e-05 | 1.261736e-08 | 2.536685e-04 | 2.366843e-08 | 1.693020e-05 | 1.959698e-08 | 3.909167e-05 | ⋯ | 8.256569e-06 | 3.579729e-05 | 2.999039e-05 | 5.166633e-05 | 3.844707e-05 | 3.312000e-08 | 5.097928e-05 | 2.352842e-04 | 9.728805e-05 | 5.721484e-05 |\n",
       "| TCGA.CR.7404.01A | 2.021346e-07 | 1.770215e-06 | 2.311015e-08 | 2.722137e-05 | 1.746742e-07 | 2.898410e-04 | 1.593500e-08 | 5.946127e-05 | 2.311015e-08 | 4.793213e-05 | ⋯ | 6.406515e-06 | 2.989495e-05 | 5.368581e-05 | 1.027929e-04 | 8.676051e-05 | 8.699464e-06 | 3.976442e-05 | 2.060475e-04 | 1.076988e-04 | 6.827457e-05 |\n",
       "| TCGA.UF.A719.01A | 2.287460e-07 | 1.194490e-06 | 4.452210e-08 | 1.156790e-05 | 1.795083e-07 | 6.265976e-04 | 1.000000e-08 | 1.573143e-04 | 1.014756e-07 | 3.996623e-05 | ⋯ | 2.240991e-05 | 3.083760e-05 | 4.057689e-05 | 8.318972e-05 | 5.420023e-05 | 5.502195e-06 | 2.682675e-05 | 2.526194e-04 | 7.717047e-05 | 3.166247e-05 |\n",
       "| TCGA.CV.7236.01A | 1.415668e-07 | 3.236452e-06 | 2.480716e-08 | 1.586300e-05 | 1.113176e-08 | 6.024393e-05 | 1.000000e-08 | 3.476194e-05 | 1.000000e-08 | 3.685805e-05 | ⋯ | 1.254780e-05 | 4.125521e-05 | 2.973344e-05 | 5.050591e-05 | 3.414947e-05 | 7.139785e-08 | 2.926980e-05 | 3.100679e-04 | 1.012570e-04 | 5.451327e-05 |\n",
       "| TCGA.CV.6951.01A | 4.044799e-07 | 4.174614e-06 | 1.000000e-08 | 1.927283e-05 | 2.988900e-07 | 6.876290e-04 | 2.264854e-07 | 1.099859e-04 | 1.950685e-07 | 3.673897e-05 | ⋯ | 9.771089e-06 | 3.152647e-05 | 1.785293e-05 | 2.334205e-05 | 4.515652e-05 | 8.247592e-07 | 2.676806e-05 | 2.145656e-04 | 1.010798e-04 | 6.089078e-05 |\n",
       "| TCGA.CN.4728.01A | 4.336213e-07 | 2.660096e-06 | 6.812478e-08 | 1.024489e-05 | 3.758464e-08 | 1.189281e-03 | 2.247877e-08 | 8.836066e-05 | 1.919488e-08 | 3.754712e-05 | ⋯ | 8.126781e-06 | 2.912493e-05 | 3.314047e-05 | 7.982748e-05 | 5.703698e-05 | 7.166923e-07 | 2.742946e-05 | 2.034198e-04 | 6.571169e-05 | 4.317406e-05 |\n",
       "| TCGA.CV.7090.01A | 1.294972e-07 | 6.863691e-07 | 1.000000e-08 | 1.133545e-05 | 1.345653e-08 | 2.727092e-05 | 1.185171e-08 | 5.001848e-06 | 1.333308e-08 | 3.332022e-05 | ⋯ | 8.960687e-06 | 2.090016e-05 | 4.915027e-05 | 4.212438e-05 | 3.918176e-05 | 1.000000e-08 | 3.281396e-05 | 4.687791e-04 | 6.574890e-05 | 3.779211e-05 |\n",
       "| TCGA.CV.5979.01A | 2.645943e-08 | 3.037834e-08 | 3.028037e-08 | 2.998465e-06 | 2.743916e-08 | 2.418532e-04 | 1.558445e-08 | 5.951702e-05 | 1.000000e-08 | 4.779614e-05 | ⋯ | 8.988522e-06 | 1.272109e-05 | 3.512541e-05 | 3.674373e-05 | 3.024813e-05 | 3.771041e-07 | 3.516098e-05 | 4.204467e-04 | 4.820018e-05 | 4.464063e-05 |\n",
       "| TCGA.CQ.7069.01A | 1.744712e-07 | 1.541398e-06 | 8.156685e-08 | 8.556673e-06 | 1.490365e-08 | 1.430076e-04 | 1.662656e-08 | 1.105873e-05 | 1.000000e-08 | 2.536097e-05 | ⋯ | 1.264765e-05 | 2.414579e-05 | 3.010678e-05 | 2.258006e-05 | 3.145634e-05 | 3.153519e-07 | 2.720858e-05 | 4.259971e-04 | 4.564460e-05 | 2.595895e-05 |\n",
       "| TCGA.CN.4733.01A | 8.847056e-08 | 1.419331e-06 | 2.457310e-08 | 1.331480e-05 | 1.313882e-08 | 3.572621e-05 | 1.022420e-08 | 6.077850e-05 | 1.560504e-08 | 5.411276e-05 | ⋯ | 1.382351e-05 | 4.042234e-05 | 2.912594e-05 | 9.503942e-05 | 2.637745e-05 | 8.398653e-08 | 2.558109e-05 | 3.552050e-04 | 8.559336e-05 | 4.522407e-05 |\n",
       "| TCGA.CR.7390.01A | 7.033687e-08 | 2.668394e-07 | 1.000000e-08 | 6.803786e-06 | 7.595381e-08 | 1.617098e-03 | 1.154013e-08 | 9.424985e-05 | 4.234274e-08 | 2.279786e-05 | ⋯ | 8.722879e-06 | 3.009699e-05 | 4.232997e-05 | 6.324648e-05 | 4.315285e-05 | 2.235216e-06 | 3.633153e-05 | 2.488503e-04 | 4.194766e-05 | 4.857112e-05 |\n",
       "| TCGA.CV.A45X.01A | 6.251957e-08 | 3.740855e-07 | 8.813362e-08 | 1.553685e-05 | 1.721068e-08 | 9.506332e-04 | 4.174851e-08 | 6.365759e-05 | 1.000000e-08 | 2.879255e-05 | ⋯ | 1.206260e-05 | 3.156587e-05 | 2.067817e-05 | 3.839815e-05 | 4.571709e-05 | 1.516817e-06 | 4.216944e-05 | 1.323282e-04 | 5.792434e-05 | 4.926701e-05 |\n",
       "| TCGA.IQ.A6SH.01A | 1.096632e-07 | 1.939058e-06 | 1.000000e-08 | 1.250559e-05 | 2.979841e-08 | 2.678809e-04 | 2.185667e-08 | 1.076140e-04 | 1.000000e-08 | 6.607560e-05 | ⋯ | 1.609883e-05 | 3.553158e-05 | 2.347749e-05 | 3.265119e-05 | 2.525442e-05 | 4.322541e-07 | 1.931993e-05 | 2.521374e-04 | 3.989081e-05 | 3.527331e-05 |\n",
       "| TCGA.CV.6962.11A | 5.200397e-08 | 2.035130e-07 | 1.000000e-08 | 2.857071e-05 | 7.698528e-08 | 4.107892e-03 | 1.000000e-08 | 1.346954e-04 | 1.000000e-08 | 2.744051e-05 | ⋯ | 5.120336e-06 | 2.686948e-05 | 1.576429e-05 | 2.542071e-05 | 1.756936e-05 | 1.320524e-06 | 2.958898e-05 | 1.754682e-04 | 7.299102e-05 | 2.940011e-05 |\n",
       "| TCGA.CV.6960.11A | 3.402361e-08 | 2.908119e-07 | 2.436819e-08 | 3.046435e-05 | 2.873612e-08 | 2.513120e-03 | 1.172418e-08 | 6.795268e-05 | 1.000000e-08 | 3.238705e-05 | ⋯ | 9.303920e-06 | 2.819361e-05 | 2.395568e-05 | 3.186382e-05 | 2.138331e-05 | 3.633425e-07 | 3.495539e-05 | 3.200481e-04 | 9.644285e-05 | 4.983267e-05 |\n",
       "| TCGA.CV.A464.01A | 1.817166e-07 | 2.650198e-06 | 4.178302e-08 | 1.272615e-05 | 1.353145e-08 | 3.495293e-05 | 2.839295e-08 | 1.456133e-05 | 1.161858e-08 | 6.225308e-05 | ⋯ | 1.449747e-05 | 3.969405e-05 | 4.049480e-05 | 5.752197e-05 | 2.347514e-05 | 2.336583e-07 | 2.786002e-05 | 2.649415e-04 | 4.804563e-05 | 3.662360e-05 |\n",
       "| TCGA.C9.A47Z.01A | 1.384600e-07 | 1.939077e-06 | 1.000000e-08 | 3.848765e-05 | 1.478949e-07 | 7.352721e-04 | 1.642818e-08 | 1.322168e-05 | 1.000000e-08 | 4.057763e-05 | ⋯ | 1.064781e-05 | 3.285023e-05 | 3.109866e-05 | 2.854366e-05 | 4.843298e-05 | 2.555151e-07 | 3.217569e-05 | 1.967548e-04 | 7.272145e-05 | 4.140324e-05 |\n",
       "| TCGA.CN.6010.01A | 1.632860e-07 | 9.065136e-07 | 2.032884e-08 | 1.705648e-05 | 3.956101e-07 | 9.547081e-05 | 1.194601e-08 | 2.303115e-04 | 3.718089e-07 | 4.849059e-05 | ⋯ | 8.693862e-06 | 3.882429e-05 | 7.222762e-05 | 8.577996e-05 | 3.221383e-05 | 1.778063e-07 | 2.927056e-05 | 1.852030e-04 | 9.048408e-05 | 5.164957e-05 |\n",
       "| TCGA.WA.A7GZ.11A | 2.786106e-07 | 1.206237e-06 | 1.425476e-07 | 9.061288e-06 | 1.184732e-06 | 3.604722e-03 | 6.955339e-08 | 3.738554e-05 | 4.143095e-08 | 1.680033e-05 | ⋯ | 1.017895e-05 | 3.332661e-05 | 1.974347e-05 | 2.994902e-05 | 1.621741e-05 | 9.469319e-07 | 1.216002e-04 | 7.325901e-05 | 5.763307e-05 | 4.442421e-05 |\n",
       "| TCGA.CV.7235.01A | 5.456606e-07 | 2.264343e-06 | 1.000000e-08 | 1.476062e-05 | 1.830712e-08 | 6.823170e-06 | 1.044502e-08 | 2.685593e-05 | 1.000000e-08 | 2.724191e-05 | ⋯ | 7.464746e-06 | 1.738329e-05 | 5.189980e-05 | 3.644026e-05 | 2.241993e-05 | 4.246480e-06 | 3.151444e-05 | 3.181916e-04 | 7.806484e-05 | 5.641338e-05 |\n",
       "| TCGA.CX.7086.01A | 1.147891e-07 | 1.070028e-06 | 2.687282e-08 | 2.155978e-05 | 9.007191e-08 | 9.884022e-04 | 2.361666e-08 | 1.391071e-04 | 1.000000e-08 | 5.256944e-05 | ⋯ | 1.074008e-05 | 2.238995e-05 | 3.763070e-05 | 4.660105e-05 | 5.250173e-05 | 8.732214e-06 | 3.691013e-05 | 2.525940e-04 | 5.755536e-05 | 4.827834e-05 |\n",
       "| TCGA.CV.6935.11A | 2.418368e-08 | 2.252219e-07 | 1.000000e-08 | 2.784939e-05 | 3.890695e-08 | 1.368549e-03 | 1.000000e-08 | 7.478171e-05 | 1.000000e-08 | 2.590137e-05 | ⋯ | 4.783886e-06 | 2.697132e-05 | 1.490085e-05 | 2.598016e-05 | 1.451628e-05 | 3.569604e-07 | 2.307343e-05 | 1.756924e-04 | 8.129718e-05 | 2.719139e-05 |\n",
       "| TCGA.P3.A6SW.01A | 5.327950e-07 | 3.094013e-06 | 3.591916e-08 | 1.301609e-05 | 1.535664e-07 | 4.412129e-05 | 2.011031e-08 | 8.193661e-05 | 1.000000e-08 | 4.864593e-05 | ⋯ | 6.382070e-06 | 2.041353e-05 | 4.462938e-05 | 1.311606e-04 | 8.395353e-05 | 9.079317e-06 | 3.005215e-05 | 1.669662e-04 | 4.795567e-05 | 6.509430e-05 |\n",
       "| TCGA.HD.A6HZ.01A | 2.867783e-07 | 9.812338e-07 | 3.947893e-07 | 1.037214e-05 | 1.133375e-07 | 3.750284e-03 | 1.519284e-08 | 1.488054e-04 | 2.246281e-08 | 4.107929e-05 | ⋯ | 9.933341e-06 | 2.955015e-05 | 5.625813e-05 | 6.994455e-05 | 3.760442e-05 | 1.012045e-06 | 4.892394e-05 | 1.442509e-04 | 8.777987e-05 | 3.475095e-05 |\n",
       "\n"
      ],
      "text/plain": [
       "                 ENSG00000121410 ENSG00000268895 ENSG00000148584\n",
       "TCGA.BB.4224.01A 7.112896e-07    1.816119e-06    9.364097e-08   \n",
       "TCGA.H7.7774.01A 1.000000e-08    3.055765e-07    1.000000e-08   \n",
       "TCGA.CV.6943.01A 4.240591e-07    2.095767e-06    2.250067e-08   \n",
       "TCGA.CN.5374.01A 5.688623e-07    3.710153e-06    7.632998e-08   \n",
       "TCGA.CQ.6227.01A 2.332942e-07    3.722853e-06    4.673325e-08   \n",
       "TCGA.CV.6959.01A 1.095189e-07    1.099285e-06    3.631508e-08   \n",
       "TCGA.F7.A61V.01A 6.488749e-08    8.260607e-07    2.762901e-08   \n",
       "TCGA.CV.7413.01A 7.152449e-07    4.564537e-06    6.039585e-08   \n",
       "TCGA.CV.7247.01A 6.327757e-08    4.347303e-07    1.000000e-08   \n",
       "TCGA.CR.5249.01A 1.204938e-07    1.304003e-06    1.000000e-08   \n",
       "TCGA.CQ.5331.01A 4.904080e-07    3.904193e-06    1.000000e-08   \n",
       "TCGA.BB.8601.01A 2.489795e-07    1.399710e-06    1.000000e-08   \n",
       "TCGA.CV.A45W.01A 3.341896e-07    1.505259e-06    4.588118e-08   \n",
       "TCGA.CQ.7063.01A 2.367013e-07    7.131626e-07    6.225785e-08   \n",
       "TCGA.CN.5373.01A 1.110500e-07    1.395054e-06    1.000000e-08   \n",
       "TCGA.CV.A45T.01A 2.311965e-07    2.848872e-06    1.000000e-08   \n",
       "TCGA.HD.A4C1.01A 1.133506e-07    8.143151e-07    2.952519e-08   \n",
       "TCGA.CV.7438.11A 2.849850e-08    7.780335e-07    1.000000e-08   \n",
       "TCGA.CV.5444.01A 6.977180e-08    9.184345e-07    6.541596e-08   \n",
       "TCGA.BA.5556.01A 1.399434e-07    2.567673e-06    2.498744e-08   \n",
       "TCGA.P3.A6SX.01A 5.295955e-07    3.703059e-06    4.578755e-08   \n",
       "TCGA.CV.7242.11A 1.447966e-07    3.584082e-07    1.842479e-08   \n",
       "TCGA.DQ.7592.01A 1.734400e-07    1.155176e-06    2.337038e-08   \n",
       "TCGA.CV.6937.01A 8.198938e-07    4.949553e-06    3.752314e-08   \n",
       "TCGA.QK.A8ZB.01A 2.837068e-07    1.510805e-06    5.124242e-08   \n",
       "TCGA.CV.7432.01A 2.393062e-07    1.143573e-06    1.000000e-08   \n",
       "TCGA.CV.7089.01A 8.247095e-08    1.471344e-06    2.661754e-08   \n",
       "TCGA.CV.6939.11A 1.000000e-08    1.000000e-08    1.000000e-08   \n",
       "TCGA.BA.4075.01A 8.208282e-08    2.119095e-06    1.737547e-07   \n",
       "TCGA.T3.A92M.01A 1.105985e-06    3.734028e-06    8.654651e-08   \n",
       "⋮                ⋮               ⋮               ⋮              \n",
       "TCGA.CV.7430.01A 5.992312e-08    4.316190e-07    4.100343e-08   \n",
       "TCGA.D6.A74Q.01A 5.906717e-07    3.218203e-06    1.000000e-08   \n",
       "TCGA.CV.7255.01A 1.000000e-08    4.927327e-08    2.262154e-08   \n",
       "TCGA.CQ.6223.01A 1.357241e-07    8.593188e-07    4.068498e-08   \n",
       "TCGA.CV.A460.01A 1.563773e-07    1.277916e-06    1.000000e-08   \n",
       "TCGA.CV.7261.01A 1.665030e-07    3.901885e-07    2.906323e-08   \n",
       "TCGA.CN.4736.01A 2.406184e-07    7.075260e-07    5.304101e-08   \n",
       "TCGA.CR.7404.01A 2.021346e-07    1.770215e-06    2.311015e-08   \n",
       "TCGA.UF.A719.01A 2.287460e-07    1.194490e-06    4.452210e-08   \n",
       "TCGA.CV.7236.01A 1.415668e-07    3.236452e-06    2.480716e-08   \n",
       "TCGA.CV.6951.01A 4.044799e-07    4.174614e-06    1.000000e-08   \n",
       "TCGA.CN.4728.01A 4.336213e-07    2.660096e-06    6.812478e-08   \n",
       "TCGA.CV.7090.01A 1.294972e-07    6.863691e-07    1.000000e-08   \n",
       "TCGA.CV.5979.01A 2.645943e-08    3.037834e-08    3.028037e-08   \n",
       "TCGA.CQ.7069.01A 1.744712e-07    1.541398e-06    8.156685e-08   \n",
       "TCGA.CN.4733.01A 8.847056e-08    1.419331e-06    2.457310e-08   \n",
       "TCGA.CR.7390.01A 7.033687e-08    2.668394e-07    1.000000e-08   \n",
       "TCGA.CV.A45X.01A 6.251957e-08    3.740855e-07    8.813362e-08   \n",
       "TCGA.IQ.A6SH.01A 1.096632e-07    1.939058e-06    1.000000e-08   \n",
       "TCGA.CV.6962.11A 5.200397e-08    2.035130e-07    1.000000e-08   \n",
       "TCGA.CV.6960.11A 3.402361e-08    2.908119e-07    2.436819e-08   \n",
       "TCGA.CV.A464.01A 1.817166e-07    2.650198e-06    4.178302e-08   \n",
       "TCGA.C9.A47Z.01A 1.384600e-07    1.939077e-06    1.000000e-08   \n",
       "TCGA.CN.6010.01A 1.632860e-07    9.065136e-07    2.032884e-08   \n",
       "TCGA.WA.A7GZ.11A 2.786106e-07    1.206237e-06    1.425476e-07   \n",
       "TCGA.CV.7235.01A 5.456606e-07    2.264343e-06    1.000000e-08   \n",
       "TCGA.CX.7086.01A 1.147891e-07    1.070028e-06    2.687282e-08   \n",
       "TCGA.CV.6935.11A 2.418368e-08    2.252219e-07    1.000000e-08   \n",
       "TCGA.P3.A6SW.01A 5.327950e-07    3.094013e-06    3.591916e-08   \n",
       "TCGA.HD.A6HZ.01A 2.867783e-07    9.812338e-07    3.947893e-07   \n",
       "                 ENSG00000175899 ENSG00000245105 ENSG00000166535\n",
       "TCGA.BB.4224.01A 3.621218e-05    1.604931e-07    1.463920e-04   \n",
       "TCGA.H7.7774.01A 2.999947e-05    9.831822e-08    2.973466e-03   \n",
       "TCGA.CV.6943.01A 1.192457e-05    1.112711e-08    6.257739e-04   \n",
       "TCGA.CN.5374.01A 2.041327e-05    4.276067e-07    3.069937e-04   \n",
       "TCGA.CQ.6227.01A 1.603208e-05    2.147914e-08    9.793864e-04   \n",
       "TCGA.CV.6959.01A 1.009195e-05    2.834081e-08    1.569075e-04   \n",
       "TCGA.F7.A61V.01A 1.661053e-05    6.526258e-08    6.957961e-04   \n",
       "TCGA.CV.7413.01A 1.069679e-05    1.346533e-08    2.421368e-04   \n",
       "TCGA.CV.7247.01A 1.534071e-05    1.596113e-08    3.955346e-04   \n",
       "TCGA.CR.5249.01A 1.972672e-05    2.524341e-07    1.275800e-03   \n",
       "TCGA.CQ.5331.01A 3.802067e-05    1.775944e-08    3.547654e-04   \n",
       "TCGA.BB.8601.01A 1.816752e-05    2.899112e-07    2.987224e-04   \n",
       "TCGA.CV.A45W.01A 1.477458e-05    7.129353e-07    7.860505e-04   \n",
       "TCGA.CQ.7063.01A 3.921091e-05    1.375956e-08    4.148020e-04   \n",
       "TCGA.CN.5373.01A 1.920272e-05    1.323611e-08    6.928735e-04   \n",
       "TCGA.CV.A45T.01A 1.690396e-05    2.381714e-08    5.877619e-04   \n",
       "TCGA.HD.A4C1.01A 9.147686e-06    1.848477e-08    1.824253e-03   \n",
       "TCGA.CV.7438.11A 2.511091e-05    4.068676e-08    2.306430e-03   \n",
       "TCGA.CV.5444.01A 1.556131e-05    1.387186e-08    3.781312e-05   \n",
       "TCGA.BA.5556.01A 2.442414e-05    1.227558e-08    5.432007e-04   \n",
       "TCGA.P3.A6SX.01A 1.191229e-05    1.730174e-08    7.153822e-05   \n",
       "TCGA.CV.7242.11A 1.848186e-05    3.684909e-08    1.828910e-03   \n",
       "TCGA.DQ.7592.01A 1.387800e-05    2.285894e-08    1.638256e-04   \n",
       "TCGA.CV.6937.01A 1.347374e-05    5.451273e-08    3.051719e-05   \n",
       "TCGA.QK.A8ZB.01A 1.222917e-05    2.405815e-08    2.458834e-04   \n",
       "TCGA.CV.7432.01A 1.585025e-05    3.435764e-08    6.326612e-05   \n",
       "TCGA.CV.7089.01A 2.982818e-05    1.246186e-08    1.587486e-03   \n",
       "TCGA.CV.6939.11A 1.000000e-08    1.000000e-08    1.000000e-08   \n",
       "TCGA.BA.4075.01A 1.032987e-06    2.971715e-08    3.250782e-06   \n",
       "TCGA.T3.A92M.01A 9.104048e-06    7.268756e-08    1.311396e-05   \n",
       "⋮                ⋮               ⋮               ⋮              \n",
       "TCGA.CV.7430.01A 1.423256e-05    7.614986e-08    8.471157e-04   \n",
       "TCGA.D6.A74Q.01A 5.075967e-06    4.651282e-08    2.866994e-04   \n",
       "TCGA.CV.7255.01A 7.523477e-06    3.039731e-08    2.023672e-04   \n",
       "TCGA.CQ.6223.01A 2.909884e-05    2.524518e-08    5.389829e-04   \n",
       "TCGA.CV.A460.01A 9.654251e-06    5.704522e-07    4.379689e-04   \n",
       "TCGA.CV.7261.01A 1.132787e-05    3.359198e-07    2.860075e-04   \n",
       "TCGA.CN.4736.01A 3.287152e-05    1.261736e-08    2.536685e-04   \n",
       "TCGA.CR.7404.01A 2.722137e-05    1.746742e-07    2.898410e-04   \n",
       "TCGA.UF.A719.01A 1.156790e-05    1.795083e-07    6.265976e-04   \n",
       "TCGA.CV.7236.01A 1.586300e-05    1.113176e-08    6.024393e-05   \n",
       "TCGA.CV.6951.01A 1.927283e-05    2.988900e-07    6.876290e-04   \n",
       "TCGA.CN.4728.01A 1.024489e-05    3.758464e-08    1.189281e-03   \n",
       "TCGA.CV.7090.01A 1.133545e-05    1.345653e-08    2.727092e-05   \n",
       "TCGA.CV.5979.01A 2.998465e-06    2.743916e-08    2.418532e-04   \n",
       "TCGA.CQ.7069.01A 8.556673e-06    1.490365e-08    1.430076e-04   \n",
       "TCGA.CN.4733.01A 1.331480e-05    1.313882e-08    3.572621e-05   \n",
       "TCGA.CR.7390.01A 6.803786e-06    7.595381e-08    1.617098e-03   \n",
       "TCGA.CV.A45X.01A 1.553685e-05    1.721068e-08    9.506332e-04   \n",
       "TCGA.IQ.A6SH.01A 1.250559e-05    2.979841e-08    2.678809e-04   \n",
       "TCGA.CV.6962.11A 2.857071e-05    7.698528e-08    4.107892e-03   \n",
       "TCGA.CV.6960.11A 3.046435e-05    2.873612e-08    2.513120e-03   \n",
       "TCGA.CV.A464.01A 1.272615e-05    1.353145e-08    3.495293e-05   \n",
       "TCGA.C9.A47Z.01A 3.848765e-05    1.478949e-07    7.352721e-04   \n",
       "TCGA.CN.6010.01A 1.705648e-05    3.956101e-07    9.547081e-05   \n",
       "TCGA.WA.A7GZ.11A 9.061288e-06    1.184732e-06    3.604722e-03   \n",
       "TCGA.CV.7235.01A 1.476062e-05    1.830712e-08    6.823170e-06   \n",
       "TCGA.CX.7086.01A 2.155978e-05    9.007191e-08    9.884022e-04   \n",
       "TCGA.CV.6935.11A 2.784939e-05    3.890695e-08    1.368549e-03   \n",
       "TCGA.P3.A6SW.01A 1.301609e-05    1.535664e-07    4.412129e-05   \n",
       "TCGA.HD.A6HZ.01A 1.037214e-05    1.133375e-07    3.750284e-03   \n",
       "                 ENSG00000256069 ENSG00000128274 ENSG00000118017\n",
       "TCGA.BB.4224.01A 1.728192e-08    8.595791e-06    1.113401e-07   \n",
       "TCGA.H7.7774.01A 1.810790e-08    6.325584e-05    1.000000e-08   \n",
       "TCGA.CV.6943.01A 1.563555e-08    5.036751e-05    1.174190e-08   \n",
       "TCGA.CN.5374.01A 8.693131e-08    1.711497e-04    8.105760e-08   \n",
       "TCGA.CQ.6227.01A 1.199637e-08    6.991207e-05    1.000000e-08   \n",
       "TCGA.CV.6959.01A 1.382765e-08    6.221136e-05    1.000000e-08   \n",
       "TCGA.F7.A61V.01A 5.576042e-08    1.660799e-04    1.000000e-08   \n",
       "TCGA.CV.7413.01A 2.089105e-08    9.714023e-06    2.237619e-08   \n",
       "TCGA.CV.7247.01A 1.102457e-08    6.344039e-05    1.000000e-08   \n",
       "TCGA.CR.5249.01A 4.587590e-08    3.842528e-05    1.000000e-08   \n",
       "TCGA.CQ.5331.01A 1.277123e-08    1.600670e-05    1.615829e-08   \n",
       "TCGA.BB.8601.01A 1.000000e-08    1.210167e-04    5.644774e-07   \n",
       "TCGA.CV.A45W.01A 1.965225e-08    6.933357e-04    1.000000e-08   \n",
       "TCGA.CQ.7063.01A 1.000000e-08    6.779595e-05    1.000000e-08   \n",
       "TCGA.CN.5373.01A 1.135708e-08    1.851542e-05    1.647221e-08   \n",
       "TCGA.CV.A45T.01A 2.650720e-08    3.745090e-05    1.000000e-08   \n",
       "TCGA.HD.A4C1.01A 1.000000e-08    2.050174e-05    1.531576e-08   \n",
       "TCGA.CV.7438.11A 3.835284e-08    4.069788e-05    1.000000e-08   \n",
       "TCGA.CV.5444.01A 1.701774e-08    2.746558e-05    1.532380e-08   \n",
       "TCGA.BA.5556.01A 1.133396e-08    1.018834e-04    1.000000e-08   \n",
       "TCGA.P3.A6SX.01A 2.153855e-08    2.714021e-05    2.135826e-08   \n",
       "TCGA.CV.7242.11A 1.385808e-08    1.005487e-04    1.000000e-08   \n",
       "TCGA.DQ.7592.01A 2.147076e-08    6.279202e-05    1.000000e-08   \n",
       "TCGA.CV.6937.01A 1.254844e-08    2.385506e-05    2.444115e-08   \n",
       "TCGA.QK.A8ZB.01A 2.957268e-08    5.870644e-05    1.489317e-08   \n",
       "TCGA.CV.7432.01A 1.229634e-08    9.838101e-06    1.000000e-08   \n",
       "TCGA.CV.7089.01A 1.038467e-08    3.785445e-05    1.000000e-08   \n",
       "TCGA.CV.6939.11A 1.000000e-08    3.745671e-04    1.000000e-08   \n",
       "TCGA.BA.4075.01A 1.652970e-08    2.960736e-05    1.512134e-08   \n",
       "TCGA.T3.A92M.01A 2.305319e-08    2.892186e-05    7.268756e-08   \n",
       "⋮                ⋮               ⋮               ⋮              \n",
       "TCGA.CV.7430.01A 1.000000e-08    6.978670e-05    2.042654e-08   \n",
       "TCGA.D6.A74Q.01A 2.156418e-08    1.291496e-04    1.000000e-08   \n",
       "TCGA.CV.7255.01A 1.129596e-08    9.066132e-05    1.000000e-08   \n",
       "TCGA.CQ.6223.01A 2.076894e-08    1.237306e-05    1.000000e-08   \n",
       "TCGA.CV.A460.01A 1.035673e-07    6.906425e-05    3.664289e-08   \n",
       "TCGA.CV.7261.01A 1.230604e-08    1.498001e-04    1.618909e-07   \n",
       "TCGA.CN.4736.01A 2.366843e-08    1.693020e-05    1.959698e-08   \n",
       "TCGA.CR.7404.01A 1.593500e-08    5.946127e-05    2.311015e-08   \n",
       "TCGA.UF.A719.01A 1.000000e-08    1.573143e-04    1.014756e-07   \n",
       "TCGA.CV.7236.01A 1.000000e-08    3.476194e-05    1.000000e-08   \n",
       "TCGA.CV.6951.01A 2.264854e-07    1.099859e-04    1.950685e-07   \n",
       "TCGA.CN.4728.01A 2.247877e-08    8.836066e-05    1.919488e-08   \n",
       "TCGA.CV.7090.01A 1.185171e-08    5.001848e-06    1.333308e-08   \n",
       "TCGA.CV.5979.01A 1.558445e-08    5.951702e-05    1.000000e-08   \n",
       "TCGA.CQ.7069.01A 1.662656e-08    1.105873e-05    1.000000e-08   \n",
       "TCGA.CN.4733.01A 1.022420e-08    6.077850e-05    1.560504e-08   \n",
       "TCGA.CR.7390.01A 1.154013e-08    9.424985e-05    4.234274e-08   \n",
       "TCGA.CV.A45X.01A 4.174851e-08    6.365759e-05    1.000000e-08   \n",
       "TCGA.IQ.A6SH.01A 2.185667e-08    1.076140e-04    1.000000e-08   \n",
       "TCGA.CV.6962.11A 1.000000e-08    1.346954e-04    1.000000e-08   \n",
       "TCGA.CV.6960.11A 1.172418e-08    6.795268e-05    1.000000e-08   \n",
       "TCGA.CV.A464.01A 2.839295e-08    1.456133e-05    1.161858e-08   \n",
       "TCGA.C9.A47Z.01A 1.642818e-08    1.322168e-05    1.000000e-08   \n",
       "TCGA.CN.6010.01A 1.194601e-08    2.303115e-04    3.718089e-07   \n",
       "TCGA.WA.A7GZ.11A 6.955339e-08    3.738554e-05    4.143095e-08   \n",
       "TCGA.CV.7235.01A 1.044502e-08    2.685593e-05    1.000000e-08   \n",
       "TCGA.CX.7086.01A 2.361666e-08    1.391071e-04    1.000000e-08   \n",
       "TCGA.CV.6935.11A 1.000000e-08    7.478171e-05    1.000000e-08   \n",
       "TCGA.P3.A6SW.01A 2.011031e-08    8.193661e-05    1.000000e-08   \n",
       "TCGA.HD.A6HZ.01A 1.519284e-08    1.488054e-04    2.246281e-08   \n",
       "                 ENSG00000094914 ⋯ ENSG00000153975 ENSG00000086827\n",
       "TCGA.BB.4224.01A 4.816970e-05    ⋯ 1.688383e-05    4.109552e-05   \n",
       "TCGA.H7.7774.01A 2.424271e-05    ⋯ 8.324437e-06    2.991585e-05   \n",
       "TCGA.CV.6943.01A 4.004534e-05    ⋯ 8.202857e-06    2.796816e-05   \n",
       "TCGA.CN.5374.01A 5.006406e-05    ⋯ 1.198679e-05    2.319999e-05   \n",
       "TCGA.CQ.6227.01A 3.144777e-05    ⋯ 1.177592e-05    3.476145e-05   \n",
       "TCGA.CV.6959.01A 4.816301e-05    ⋯ 1.093267e-05    2.184035e-05   \n",
       "TCGA.F7.A61V.01A 4.595533e-05    ⋯ 1.254223e-05    3.845450e-05   \n",
       "TCGA.CV.7413.01A 7.070657e-05    ⋯ 1.180174e-05    3.282413e-05   \n",
       "TCGA.CV.7247.01A 3.543493e-05    ⋯ 8.242409e-06    2.878184e-05   \n",
       "TCGA.CR.5249.01A 4.347034e-05    ⋯ 1.001275e-05    2.092357e-05   \n",
       "TCGA.CQ.5331.01A 3.917818e-05    ⋯ 1.344621e-05    3.188899e-05   \n",
       "TCGA.BB.8601.01A 6.030766e-05    ⋯ 1.576661e-05    3.774724e-05   \n",
       "TCGA.CV.A45W.01A 7.564479e-05    ⋯ 1.219932e-05    3.475431e-05   \n",
       "TCGA.CQ.7063.01A 3.503893e-05    ⋯ 1.220162e-05    3.380328e-05   \n",
       "TCGA.CN.5373.01A 2.462936e-05    ⋯ 8.555410e-06    2.546115e-05   \n",
       "TCGA.CV.A45T.01A 4.425150e-05    ⋯ 9.461779e-06    3.674317e-05   \n",
       "TCGA.HD.A4C1.01A 3.385155e-05    ⋯ 1.375154e-05    3.996538e-05   \n",
       "TCGA.CV.7438.11A 3.582102e-05    ⋯ 9.986137e-06    3.280438e-05   \n",
       "TCGA.CV.5444.01A 5.458818e-05    ⋯ 1.109198e-05    3.447969e-05   \n",
       "TCGA.BA.5556.01A 3.673644e-05    ⋯ 9.226567e-06    3.810100e-05   \n",
       "TCGA.P3.A6SX.01A 6.914316e-05    ⋯ 1.010506e-05    2.535398e-05   \n",
       "TCGA.CV.7242.11A 3.572110e-05    ⋯ 9.388835e-06    3.151705e-05   \n",
       "TCGA.DQ.7592.01A 3.828361e-05    ⋯ 1.246155e-05    2.848459e-05   \n",
       "TCGA.CV.6937.01A 5.597677e-05    ⋯ 1.083458e-05    2.587512e-05   \n",
       "TCGA.QK.A8ZB.01A 4.413466e-05    ⋯ 1.438504e-05    4.190057e-05   \n",
       "TCGA.CV.7432.01A 5.061828e-05    ⋯ 7.323606e-06    2.347354e-05   \n",
       "TCGA.CV.7089.01A 4.696895e-05    ⋯ 8.723132e-06    2.817704e-05   \n",
       "TCGA.CV.6939.11A 1.000000e-08    ⋯ 1.000000e-08    1.000000e-08   \n",
       "TCGA.BA.4075.01A 3.313814e-05    ⋯ 1.279785e-05    2.892712e-05   \n",
       "TCGA.T3.A92M.01A 5.626057e-05    ⋯ 1.786274e-05    2.432842e-05   \n",
       "⋮                ⋮               ⋱ ⋮               ⋮              \n",
       "TCGA.CV.7430.01A 3.853621e-05    ⋯ 1.264069e-05    3.960967e-05   \n",
       "TCGA.D6.A74Q.01A 5.972753e-05    ⋯ 1.532419e-05    2.926941e-05   \n",
       "TCGA.CV.7255.01A 4.400175e-05    ⋯ 1.139795e-05    3.899337e-05   \n",
       "TCGA.CQ.6223.01A 2.535573e-05    ⋯ 9.995334e-06    2.695394e-05   \n",
       "TCGA.CV.A460.01A 6.853885e-05    ⋯ 1.474273e-05    2.165545e-05   \n",
       "TCGA.CV.7261.01A 4.263600e-05    ⋯ 1.691570e-05    5.612231e-05   \n",
       "TCGA.CN.4736.01A 3.909167e-05    ⋯ 8.256569e-06    3.579729e-05   \n",
       "TCGA.CR.7404.01A 4.793213e-05    ⋯ 6.406515e-06    2.989495e-05   \n",
       "TCGA.UF.A719.01A 3.996623e-05    ⋯ 2.240991e-05    3.083760e-05   \n",
       "TCGA.CV.7236.01A 3.685805e-05    ⋯ 1.254780e-05    4.125521e-05   \n",
       "TCGA.CV.6951.01A 3.673897e-05    ⋯ 9.771089e-06    3.152647e-05   \n",
       "TCGA.CN.4728.01A 3.754712e-05    ⋯ 8.126781e-06    2.912493e-05   \n",
       "TCGA.CV.7090.01A 3.332022e-05    ⋯ 8.960687e-06    2.090016e-05   \n",
       "TCGA.CV.5979.01A 4.779614e-05    ⋯ 8.988522e-06    1.272109e-05   \n",
       "TCGA.CQ.7069.01A 2.536097e-05    ⋯ 1.264765e-05    2.414579e-05   \n",
       "TCGA.CN.4733.01A 5.411276e-05    ⋯ 1.382351e-05    4.042234e-05   \n",
       "TCGA.CR.7390.01A 2.279786e-05    ⋯ 8.722879e-06    3.009699e-05   \n",
       "TCGA.CV.A45X.01A 2.879255e-05    ⋯ 1.206260e-05    3.156587e-05   \n",
       "TCGA.IQ.A6SH.01A 6.607560e-05    ⋯ 1.609883e-05    3.553158e-05   \n",
       "TCGA.CV.6962.11A 2.744051e-05    ⋯ 5.120336e-06    2.686948e-05   \n",
       "TCGA.CV.6960.11A 3.238705e-05    ⋯ 9.303920e-06    2.819361e-05   \n",
       "TCGA.CV.A464.01A 6.225308e-05    ⋯ 1.449747e-05    3.969405e-05   \n",
       "TCGA.C9.A47Z.01A 4.057763e-05    ⋯ 1.064781e-05    3.285023e-05   \n",
       "TCGA.CN.6010.01A 4.849059e-05    ⋯ 8.693862e-06    3.882429e-05   \n",
       "TCGA.WA.A7GZ.11A 1.680033e-05    ⋯ 1.017895e-05    3.332661e-05   \n",
       "TCGA.CV.7235.01A 2.724191e-05    ⋯ 7.464746e-06    1.738329e-05   \n",
       "TCGA.CX.7086.01A 5.256944e-05    ⋯ 1.074008e-05    2.238995e-05   \n",
       "TCGA.CV.6935.11A 2.590137e-05    ⋯ 4.783886e-06    2.697132e-05   \n",
       "TCGA.P3.A6SW.01A 4.864593e-05    ⋯ 6.382070e-06    2.041353e-05   \n",
       "TCGA.HD.A6HZ.01A 4.107929e-05    ⋯ 9.933341e-06    2.955015e-05   \n",
       "                 ENSG00000174442 ENSG00000122952 ENSG00000070476\n",
       "TCGA.BB.4224.01A 4.948895e-05    2.232009e-04    6.436126e-05   \n",
       "TCGA.H7.7774.01A 1.176516e-05    2.554113e-05    1.917238e-05   \n",
       "TCGA.CV.6943.01A 2.079954e-05    3.936395e-05    1.792602e-05   \n",
       "TCGA.CN.5374.01A 5.350305e-05    1.639979e-04    5.114597e-05   \n",
       "TCGA.CQ.6227.01A 3.677868e-05    4.817377e-05    1.521257e-05   \n",
       "TCGA.CV.6959.01A 5.181435e-05    6.009834e-05    3.105542e-05   \n",
       "TCGA.F7.A61V.01A 3.403099e-05    8.593618e-05    5.133781e-05   \n",
       "TCGA.CV.7413.01A 3.526789e-05    4.109272e-05    3.621323e-05   \n",
       "TCGA.CV.7247.01A 5.191763e-05    9.079134e-05    2.787398e-05   \n",
       "TCGA.CR.5249.01A 4.553226e-05    1.109087e-04    4.417026e-05   \n",
       "TCGA.CQ.5331.01A 3.083241e-05    4.320952e-05    2.665635e-05   \n",
       "TCGA.BB.8601.01A 5.166895e-05    4.469663e-05    6.560713e-05   \n",
       "TCGA.CV.A45W.01A 4.183087e-05    6.151852e-05    5.860921e-05   \n",
       "TCGA.CQ.7063.01A 2.501544e-05    3.378373e-05    2.725200e-05   \n",
       "TCGA.CN.5373.01A 1.713736e-05    2.721261e-05    3.433372e-05   \n",
       "TCGA.CV.A45T.01A 2.409327e-05    6.648291e-05    2.232908e-05   \n",
       "TCGA.HD.A4C1.01A 4.140943e-05    5.820150e-05    3.268607e-05   \n",
       "TCGA.CV.7438.11A 2.201708e-05    2.936764e-05    1.825384e-05   \n",
       "TCGA.CV.5444.01A 3.425125e-05    9.014054e-05    4.267545e-05   \n",
       "TCGA.BA.5556.01A 2.496581e-05    4.480619e-05    2.826359e-05   \n",
       "TCGA.P3.A6SX.01A 4.251470e-05    7.067788e-05    4.601701e-05   \n",
       "TCGA.CV.7242.11A 2.339004e-05    4.435776e-05    1.519887e-05   \n",
       "TCGA.DQ.7592.01A 2.688416e-05    5.692476e-05    3.370240e-05   \n",
       "TCGA.CV.6937.01A 1.330435e-05    4.541689e-05    6.192550e-05   \n",
       "TCGA.QK.A8ZB.01A 3.191098e-05    3.159906e-05    3.714488e-05   \n",
       "TCGA.CV.7432.01A 2.809034e-05    6.897467e-05    2.389131e-05   \n",
       "TCGA.CV.7089.01A 3.291789e-05    6.626445e-05    3.203185e-05   \n",
       "TCGA.CV.6939.11A 1.000000e-08    1.000000e-08    1.000000e-08   \n",
       "TCGA.BA.4075.01A 4.382560e-05    4.240033e-05    1.784301e-05   \n",
       "TCGA.T3.A92M.01A 4.703002e-05    1.091200e-04    6.208567e-05   \n",
       "⋮                ⋮               ⋮               ⋮              \n",
       "TCGA.CV.7430.01A 3.717462e-05    4.984853e-05    4.044724e-05   \n",
       "TCGA.D6.A74Q.01A 3.902315e-05    1.499300e-04    3.898235e-05   \n",
       "TCGA.CV.7255.01A 3.734795e-05    4.424697e-05    4.001470e-05   \n",
       "TCGA.CQ.6223.01A 2.243365e-05    4.489370e-05    4.750166e-05   \n",
       "TCGA.CV.A460.01A 3.136948e-05    5.283001e-05    4.540727e-05   \n",
       "TCGA.CV.7261.01A 5.952034e-05    6.640847e-05    6.396268e-05   \n",
       "TCGA.CN.4736.01A 2.999039e-05    5.166633e-05    3.844707e-05   \n",
       "TCGA.CR.7404.01A 5.368581e-05    1.027929e-04    8.676051e-05   \n",
       "TCGA.UF.A719.01A 4.057689e-05    8.318972e-05    5.420023e-05   \n",
       "TCGA.CV.7236.01A 2.973344e-05    5.050591e-05    3.414947e-05   \n",
       "TCGA.CV.6951.01A 1.785293e-05    2.334205e-05    4.515652e-05   \n",
       "TCGA.CN.4728.01A 3.314047e-05    7.982748e-05    5.703698e-05   \n",
       "TCGA.CV.7090.01A 4.915027e-05    4.212438e-05    3.918176e-05   \n",
       "TCGA.CV.5979.01A 3.512541e-05    3.674373e-05    3.024813e-05   \n",
       "TCGA.CQ.7069.01A 3.010678e-05    2.258006e-05    3.145634e-05   \n",
       "TCGA.CN.4733.01A 2.912594e-05    9.503942e-05    2.637745e-05   \n",
       "TCGA.CR.7390.01A 4.232997e-05    6.324648e-05    4.315285e-05   \n",
       "TCGA.CV.A45X.01A 2.067817e-05    3.839815e-05    4.571709e-05   \n",
       "TCGA.IQ.A6SH.01A 2.347749e-05    3.265119e-05    2.525442e-05   \n",
       "TCGA.CV.6962.11A 1.576429e-05    2.542071e-05    1.756936e-05   \n",
       "TCGA.CV.6960.11A 2.395568e-05    3.186382e-05    2.138331e-05   \n",
       "TCGA.CV.A464.01A 4.049480e-05    5.752197e-05    2.347514e-05   \n",
       "TCGA.C9.A47Z.01A 3.109866e-05    2.854366e-05    4.843298e-05   \n",
       "TCGA.CN.6010.01A 7.222762e-05    8.577996e-05    3.221383e-05   \n",
       "TCGA.WA.A7GZ.11A 1.974347e-05    2.994902e-05    1.621741e-05   \n",
       "TCGA.CV.7235.01A 5.189980e-05    3.644026e-05    2.241993e-05   \n",
       "TCGA.CX.7086.01A 3.763070e-05    4.660105e-05    5.250173e-05   \n",
       "TCGA.CV.6935.11A 1.490085e-05    2.598016e-05    1.451628e-05   \n",
       "TCGA.P3.A6SW.01A 4.462938e-05    1.311606e-04    8.395353e-05   \n",
       "TCGA.HD.A6HZ.01A 5.625813e-05    6.994455e-05    3.760442e-05   \n",
       "                 ENSG00000203995 ENSG00000162378 ENSG00000159840\n",
       "TCGA.BB.4224.01A 8.086158e-06    4.401456e-05    6.694816e-05   \n",
       "TCGA.H7.7774.01A 1.049839e-06    3.525809e-05    2.250746e-04   \n",
       "TCGA.CV.6943.01A 5.487945e-08    1.907782e-05    2.410835e-04   \n",
       "TCGA.CN.5374.01A 5.912365e-06    2.957125e-05    1.426902e-04   \n",
       "TCGA.CQ.6227.01A 8.158356e-07    3.049380e-05    3.080264e-04   \n",
       "TCGA.CV.6959.01A 5.593178e-08    2.774777e-05    3.850048e-04   \n",
       "TCGA.F7.A61V.01A 7.236624e-07    2.285670e-05    1.580313e-04   \n",
       "TCGA.CV.7413.01A 7.663341e-08    2.347080e-05    1.550597e-04   \n",
       "TCGA.CV.7247.01A 1.784460e-06    2.728132e-05    1.733255e-04   \n",
       "TCGA.CR.5249.01A 4.727433e-06    4.064770e-05    2.483755e-04   \n",
       "TCGA.CQ.5331.01A 1.130897e-07    3.676192e-05    1.451680e-04   \n",
       "TCGA.BB.8601.01A 2.364771e-06    1.835305e-05    2.435944e-04   \n",
       "TCGA.CV.A45W.01A 5.503807e-06    2.351070e-05    1.689415e-04   \n",
       "TCGA.CQ.7063.01A 1.246665e-07    2.473861e-05    3.740954e-04   \n",
       "TCGA.CN.5373.01A 2.469665e-07    3.476788e-05    1.786924e-04   \n",
       "TCGA.CV.A45T.01A 2.283842e-07    2.562306e-05    2.979540e-04   \n",
       "TCGA.HD.A4C1.01A 2.484935e-07    4.006986e-05    2.865009e-04   \n",
       "TCGA.CV.7438.11A 7.567689e-07    2.819463e-05    2.549497e-04   \n",
       "TCGA.CV.5444.01A 1.694721e-07    3.367386e-05    2.155933e-04   \n",
       "TCGA.BA.5556.01A 9.223473e-08    3.382087e-05    3.820152e-04   \n",
       "TCGA.P3.A6SX.01A 2.759241e-06    2.782909e-05    1.228729e-04   \n",
       "TCGA.CV.7242.11A 4.655684e-07    2.436527e-05    2.302738e-04   \n",
       "TCGA.DQ.7592.01A 1.622993e-06    3.422983e-05    3.782780e-04   \n",
       "TCGA.CV.6937.01A 4.148619e-07    4.509375e-05    2.291824e-04   \n",
       "TCGA.QK.A8ZB.01A 7.877809e-07    3.547662e-05    1.745106e-04   \n",
       "TCGA.CV.7432.01A 2.754048e-06    1.806278e-05    4.240103e-04   \n",
       "TCGA.CV.7089.01A 3.701237e-07    2.995689e-05    3.655372e-04   \n",
       "TCGA.CV.6939.11A 1.000000e-08    1.000000e-08    1.000000e-08   \n",
       "TCGA.BA.4075.01A 8.361922e-08    2.020586e-05    2.721516e-04   \n",
       "TCGA.T3.A92M.01A 3.187889e-06    3.233632e-05    1.889197e-04   \n",
       "⋮                ⋮               ⋮               ⋮              \n",
       "TCGA.CV.7430.01A 3.036183e-06    3.712124e-05    2.335524e-04   \n",
       "TCGA.D6.A74Q.01A 3.639974e-06    1.956117e-05    3.995424e-04   \n",
       "TCGA.CV.7255.01A 7.762513e-07    4.356174e-05    3.151445e-04   \n",
       "TCGA.CQ.6223.01A 2.506792e-07    2.826659e-05    3.110916e-04   \n",
       "TCGA.CV.A460.01A 2.012023e-06    3.496452e-05    1.878741e-04   \n",
       "TCGA.CV.7261.01A 3.700491e-07    2.714467e-05    3.126007e-04   \n",
       "TCGA.CN.4736.01A 3.312000e-08    5.097928e-05    2.352842e-04   \n",
       "TCGA.CR.7404.01A 8.699464e-06    3.976442e-05    2.060475e-04   \n",
       "TCGA.UF.A719.01A 5.502195e-06    2.682675e-05    2.526194e-04   \n",
       "TCGA.CV.7236.01A 7.139785e-08    2.926980e-05    3.100679e-04   \n",
       "TCGA.CV.6951.01A 8.247592e-07    2.676806e-05    2.145656e-04   \n",
       "TCGA.CN.4728.01A 7.166923e-07    2.742946e-05    2.034198e-04   \n",
       "TCGA.CV.7090.01A 1.000000e-08    3.281396e-05    4.687791e-04   \n",
       "TCGA.CV.5979.01A 3.771041e-07    3.516098e-05    4.204467e-04   \n",
       "TCGA.CQ.7069.01A 3.153519e-07    2.720858e-05    4.259971e-04   \n",
       "TCGA.CN.4733.01A 8.398653e-08    2.558109e-05    3.552050e-04   \n",
       "TCGA.CR.7390.01A 2.235216e-06    3.633153e-05    2.488503e-04   \n",
       "TCGA.CV.A45X.01A 1.516817e-06    4.216944e-05    1.323282e-04   \n",
       "TCGA.IQ.A6SH.01A 4.322541e-07    1.931993e-05    2.521374e-04   \n",
       "TCGA.CV.6962.11A 1.320524e-06    2.958898e-05    1.754682e-04   \n",
       "TCGA.CV.6960.11A 3.633425e-07    3.495539e-05    3.200481e-04   \n",
       "TCGA.CV.A464.01A 2.336583e-07    2.786002e-05    2.649415e-04   \n",
       "TCGA.C9.A47Z.01A 2.555151e-07    3.217569e-05    1.967548e-04   \n",
       "TCGA.CN.6010.01A 1.778063e-07    2.927056e-05    1.852030e-04   \n",
       "TCGA.WA.A7GZ.11A 9.469319e-07    1.216002e-04    7.325901e-05   \n",
       "TCGA.CV.7235.01A 4.246480e-06    3.151444e-05    3.181916e-04   \n",
       "TCGA.CX.7086.01A 8.732214e-06    3.691013e-05    2.525940e-04   \n",
       "TCGA.CV.6935.11A 3.569604e-07    2.307343e-05    1.756924e-04   \n",
       "TCGA.P3.A6SW.01A 9.079317e-06    3.005215e-05    1.669662e-04   \n",
       "TCGA.HD.A6HZ.01A 1.012045e-06    4.892394e-05    1.442509e-04   \n",
       "                 ENSG00000074755 ENSG00000036549\n",
       "TCGA.BB.4224.01A 4.885926e-05    5.912475e-05   \n",
       "TCGA.H7.7774.01A 7.796061e-05    2.826495e-05   \n",
       "TCGA.CV.6943.01A 8.432179e-05    3.307693e-05   \n",
       "TCGA.CN.5374.01A 5.812695e-05    8.976578e-05   \n",
       "TCGA.CQ.6227.01A 5.208826e-05    4.512052e-05   \n",
       "TCGA.CV.6959.01A 7.340731e-05    5.111540e-05   \n",
       "TCGA.F7.A61V.01A 4.675939e-05    4.992411e-05   \n",
       "TCGA.CV.7413.01A 6.976865e-05    4.175598e-05   \n",
       "TCGA.CV.7247.01A 5.414169e-05    6.122369e-05   \n",
       "TCGA.CR.5249.01A 9.212467e-05    5.698468e-05   \n",
       "TCGA.CQ.5331.01A 1.057671e-04    4.379419e-05   \n",
       "TCGA.BB.8601.01A 3.309973e-05    3.577703e-05   \n",
       "TCGA.CV.A45W.01A 5.725936e-05    4.625916e-05   \n",
       "TCGA.CQ.7063.01A 8.947594e-05    3.327431e-05   \n",
       "TCGA.CN.5373.01A 8.323724e-05    3.471464e-05   \n",
       "TCGA.CV.A45T.01A 5.079728e-05    4.287382e-05   \n",
       "TCGA.HD.A4C1.01A 8.858985e-05    5.208715e-05   \n",
       "TCGA.CV.7438.11A 6.962642e-05    4.188256e-05   \n",
       "TCGA.CV.5444.01A 6.592546e-05    5.377485e-05   \n",
       "TCGA.BA.5556.01A 1.145747e-04    3.953509e-05   \n",
       "TCGA.P3.A6SX.01A 5.473565e-05    6.273034e-05   \n",
       "TCGA.CV.7242.11A 6.842738e-05    3.747306e-05   \n",
       "TCGA.DQ.7592.01A 9.691256e-05    5.087237e-05   \n",
       "TCGA.CV.6937.01A 6.211986e-05    3.248849e-05   \n",
       "TCGA.QK.A8ZB.01A 5.561768e-05    4.968794e-05   \n",
       "TCGA.CV.7432.01A 6.424363e-05    6.081059e-05   \n",
       "TCGA.CV.7089.01A 5.180273e-05    3.228027e-05   \n",
       "TCGA.CV.6939.11A 1.248624e-04    1.000000e-08   \n",
       "TCGA.BA.4075.01A 1.280451e-05    5.767805e-05   \n",
       "TCGA.T3.A92M.01A 6.236092e-05    3.629111e-05   \n",
       "⋮                ⋮               ⋮              \n",
       "TCGA.CV.7430.01A 8.635110e-05    5.497010e-05   \n",
       "TCGA.D6.A74Q.01A 3.777732e-05    3.815455e-05   \n",
       "TCGA.CV.7255.01A 8.641293e-05    5.587264e-05   \n",
       "TCGA.CQ.6223.01A 5.003158e-05    3.253504e-05   \n",
       "TCGA.CV.A460.01A 5.432899e-05    5.297623e-05   \n",
       "TCGA.CV.7261.01A 6.837413e-05    4.239125e-05   \n",
       "TCGA.CN.4736.01A 9.728805e-05    5.721484e-05   \n",
       "TCGA.CR.7404.01A 1.076988e-04    6.827457e-05   \n",
       "TCGA.UF.A719.01A 7.717047e-05    3.166247e-05   \n",
       "TCGA.CV.7236.01A 1.012570e-04    5.451327e-05   \n",
       "TCGA.CV.6951.01A 1.010798e-04    6.089078e-05   \n",
       "TCGA.CN.4728.01A 6.571169e-05    4.317406e-05   \n",
       "TCGA.CV.7090.01A 6.574890e-05    3.779211e-05   \n",
       "TCGA.CV.5979.01A 4.820018e-05    4.464063e-05   \n",
       "TCGA.CQ.7069.01A 4.564460e-05    2.595895e-05   \n",
       "TCGA.CN.4733.01A 8.559336e-05    4.522407e-05   \n",
       "TCGA.CR.7390.01A 4.194766e-05    4.857112e-05   \n",
       "TCGA.CV.A45X.01A 5.792434e-05    4.926701e-05   \n",
       "TCGA.IQ.A6SH.01A 3.989081e-05    3.527331e-05   \n",
       "TCGA.CV.6962.11A 7.299102e-05    2.940011e-05   \n",
       "TCGA.CV.6960.11A 9.644285e-05    4.983267e-05   \n",
       "TCGA.CV.A464.01A 4.804563e-05    3.662360e-05   \n",
       "TCGA.C9.A47Z.01A 7.272145e-05    4.140324e-05   \n",
       "TCGA.CN.6010.01A 9.048408e-05    5.164957e-05   \n",
       "TCGA.WA.A7GZ.11A 5.763307e-05    4.442421e-05   \n",
       "TCGA.CV.7235.01A 7.806484e-05    5.641338e-05   \n",
       "TCGA.CX.7086.01A 5.755536e-05    4.827834e-05   \n",
       "TCGA.CV.6935.11A 8.129718e-05    2.719139e-05   \n",
       "TCGA.P3.A6SW.01A 4.795567e-05    6.509430e-05   \n",
       "TCGA.HD.A6HZ.01A 8.777987e-05    3.475095e-05   "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "# the normalized expression of malignant cells inferred by the \n",
    "# deconvolution module of BayesPrism\n",
    "res1$res$first.gibbs.res$Zkg.tum.norm"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 3,
   "id": "be7f69b7",
   "metadata": {
    "collapsed": true
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<table class=\"dataframe\">\n",
       "<caption>A matrix: 9 × 18234 of type dbl</caption>\n",
       "<thead>\n",
       "\t<tr><th></th><th scope=col>ENSG00000121410</th><th scope=col>ENSG00000268895</th><th scope=col>ENSG00000148584</th><th scope=col>ENSG00000175899</th><th scope=col>ENSG00000245105</th><th scope=col>ENSG00000166535</th><th scope=col>ENSG00000256069</th><th scope=col>ENSG00000128274</th><th scope=col>ENSG00000118017</th><th scope=col>ENSG00000094914</th><th scope=col>⋯</th><th scope=col>ENSG00000153975</th><th scope=col>ENSG00000086827</th><th scope=col>ENSG00000174442</th><th scope=col>ENSG00000122952</th><th scope=col>ENSG00000070476</th><th scope=col>ENSG00000203995</th><th scope=col>ENSG00000162378</th><th scope=col>ENSG00000159840</th><th scope=col>ENSG00000074755</th><th scope=col>ENSG00000036549</th></tr>\n",
       "</thead>\n",
       "<tbody>\n",
       "\t<tr><th scope=row>Fibroblast</th><td>4.790526e-07</td><td>3.048030e-06</td><td>5.382811e-08</td><td>1.240567e-03</td><td>2.094833e-06</td><td>3.366184e-05</td><td>7.236724e-09</td><td>1.393013e-04</td><td>2.281876e-07</td><td>3.339089e-05</td><td>⋯</td><td>6.564508e-06</td><td>1.760142e-05</td><td>1.410649e-05</td><td>4.544236e-06</td><td>4.750947e-05</td><td>3.636425e-06</td><td>6.375454e-05</td><td>4.416710e-04</td><td>9.048196e-05</td><td>3.904093e-05</td></tr>\n",
       "\t<tr><th scope=row>B cell</th><td>1.655977e-06</td><td>3.033846e-06</td><td>3.499550e-08</td><td>8.575522e-06</td><td>2.838517e-07</td><td>3.172259e-05</td><td>5.312870e-09</td><td>1.333111e-08</td><td>8.352407e-09</td><td>4.948197e-05</td><td>⋯</td><td>1.283167e-05</td><td>2.093139e-05</td><td>3.263562e-05</td><td>2.451176e-05</td><td>5.335222e-05</td><td>1.418179e-05</td><td>4.343860e-05</td><td>6.161845e-05</td><td>7.989676e-05</td><td>2.023588e-05</td></tr>\n",
       "\t<tr><th scope=row>myocyte</th><td>1.071422e-09</td><td>2.065976e-09</td><td>2.715623e-09</td><td>1.057379e-03</td><td>7.556871e-09</td><td>5.537073e-06</td><td>1.350077e-08</td><td>5.086130e-05</td><td>6.752496e-09</td><td>7.624092e-05</td><td>⋯</td><td>1.688090e-06</td><td>1.007480e-05</td><td>1.787889e-06</td><td>5.928562e-09</td><td>5.594272e-05</td><td>2.477242e-06</td><td>4.152031e-05</td><td>1.598354e-04</td><td>1.092872e-04</td><td>2.347115e-05</td></tr>\n",
       "\t<tr><th scope=row></th><td>1.844932e-07</td><td>9.019386e-07</td><td>7.031525e-08</td><td>3.637507e-04</td><td>8.086174e-07</td><td>2.698824e-04</td><td>1.070870e-08</td><td>8.383799e-05</td><td>6.920277e-09</td><td>2.908657e-05</td><td>⋯</td><td>8.870377e-06</td><td>1.686399e-05</td><td>1.544228e-05</td><td>1.870010e-05</td><td>6.114980e-05</td><td>8.260690e-06</td><td>6.257270e-05</td><td>1.990281e-04</td><td>6.867232e-05</td><td>2.681214e-05</td></tr>\n",
       "\t<tr><th scope=row>Macrophage</th><td>3.298288e-07</td><td>1.411043e-06</td><td>9.989069e-09</td><td>7.210862e-04</td><td>1.376798e-06</td><td>1.566517e-05</td><td>6.532266e-09</td><td>1.496544e-08</td><td>1.015744e-08</td><td>4.821042e-05</td><td>⋯</td><td>1.604892e-05</td><td>1.957888e-05</td><td>2.943255e-05</td><td>5.904993e-05</td><td>4.087582e-05</td><td>2.106199e-06</td><td>3.832560e-05</td><td>5.589237e-04</td><td>4.206303e-05</td><td>2.676705e-05</td></tr>\n",
       "\t<tr><th scope=row>Endothelial</th><td>1.282867e-07</td><td>9.413568e-07</td><td>6.884161e-08</td><td>1.450910e-03</td><td>4.211413e-06</td><td>3.825659e-05</td><td>4.536466e-06</td><td>1.515922e-04</td><td>9.501013e-09</td><td>2.822296e-05</td><td>⋯</td><td>1.327456e-05</td><td>1.881648e-05</td><td>2.625536e-05</td><td>1.812981e-05</td><td>5.772141e-05</td><td>7.044692e-06</td><td>6.718225e-05</td><td>3.190477e-04</td><td>1.009169e-04</td><td>3.883224e-05</td></tr>\n",
       "\t<tr><th scope=row>T cell</th><td>3.851666e-07</td><td>1.088591e-06</td><td>1.762161e-07</td><td>3.269938e-05</td><td>1.162382e-06</td><td>8.054513e-05</td><td>6.696823e-07</td><td>1.499636e-06</td><td>2.875079e-07</td><td>1.771516e-05</td><td>⋯</td><td>1.541649e-05</td><td>1.309156e-05</td><td>3.134094e-05</td><td>4.300053e-05</td><td>9.319480e-05</td><td>2.503748e-05</td><td>6.932394e-05</td><td>2.367922e-04</td><td>1.188224e-04</td><td>4.305001e-05</td></tr>\n",
       "\t<tr><th scope=row>Dendritic</th><td>9.554070e-07</td><td>6.553169e-08</td><td>9.309546e-08</td><td>3.239208e-05</td><td>1.002456e-07</td><td>2.712358e-05</td><td>4.277995e-09</td><td>1.690812e-08</td><td>8.519275e-09</td><td>6.941841e-06</td><td>⋯</td><td>3.615964e-05</td><td>1.543686e-05</td><td>4.610866e-05</td><td>1.262511e-05</td><td>4.199085e-05</td><td>2.104540e-05</td><td>3.008003e-05</td><td>3.829456e-04</td><td>9.742747e-05</td><td>6.903309e-05</td></tr>\n",
       "\t<tr><th scope=row>Mast</th><td>7.083485e-07</td><td>4.897996e-06</td><td>5.085302e-07</td><td>1.455733e-04</td><td>5.888258e-06</td><td>9.364647e-05</td><td>9.013286e-06</td><td>6.846619e-06</td><td>9.594516e-09</td><td>1.842756e-05</td><td>⋯</td><td>1.354589e-05</td><td>6.861964e-06</td><td>2.406780e-05</td><td>1.090380e-05</td><td>8.286390e-05</td><td>8.903383e-06</td><td>5.111216e-05</td><td>9.390497e-05</td><td>5.997305e-05</td><td>3.087020e-05</td></tr>\n",
       "</tbody>\n",
       "</table>\n"
      ],
      "text/latex": [
       "A matrix: 9 × 18234 of type dbl\n",
       "\\begin{tabular}{r|lllllllllllllllllllll}\n",
       "  & ENSG00000121410 & ENSG00000268895 & ENSG00000148584 & ENSG00000175899 & ENSG00000245105 & ENSG00000166535 & ENSG00000256069 & ENSG00000128274 & ENSG00000118017 & ENSG00000094914 & ⋯ & ENSG00000153975 & ENSG00000086827 & ENSG00000174442 & ENSG00000122952 & ENSG00000070476 & ENSG00000203995 & ENSG00000162378 & ENSG00000159840 & ENSG00000074755 & ENSG00000036549\\\\\n",
       "\\hline\n",
       "\tFibroblast & 4.790526e-07 & 3.048030e-06 & 5.382811e-08 & 1.240567e-03 & 2.094833e-06 & 3.366184e-05 & 7.236724e-09 & 1.393013e-04 & 2.281876e-07 & 3.339089e-05 & ⋯ & 6.564508e-06 & 1.760142e-05 & 1.410649e-05 & 4.544236e-06 & 4.750947e-05 & 3.636425e-06 & 6.375454e-05 & 4.416710e-04 & 9.048196e-05 & 3.904093e-05\\\\\n",
       "\tB cell & 1.655977e-06 & 3.033846e-06 & 3.499550e-08 & 8.575522e-06 & 2.838517e-07 & 3.172259e-05 & 5.312870e-09 & 1.333111e-08 & 8.352407e-09 & 4.948197e-05 & ⋯ & 1.283167e-05 & 2.093139e-05 & 3.263562e-05 & 2.451176e-05 & 5.335222e-05 & 1.418179e-05 & 4.343860e-05 & 6.161845e-05 & 7.989676e-05 & 2.023588e-05\\\\\n",
       "\tmyocyte & 1.071422e-09 & 2.065976e-09 & 2.715623e-09 & 1.057379e-03 & 7.556871e-09 & 5.537073e-06 & 1.350077e-08 & 5.086130e-05 & 6.752496e-09 & 7.624092e-05 & ⋯ & 1.688090e-06 & 1.007480e-05 & 1.787889e-06 & 5.928562e-09 & 5.594272e-05 & 2.477242e-06 & 4.152031e-05 & 1.598354e-04 & 1.092872e-04 & 2.347115e-05\\\\\n",
       "\t & 1.844932e-07 & 9.019386e-07 & 7.031525e-08 & 3.637507e-04 & 8.086174e-07 & 2.698824e-04 & 1.070870e-08 & 8.383799e-05 & 6.920277e-09 & 2.908657e-05 & ⋯ & 8.870377e-06 & 1.686399e-05 & 1.544228e-05 & 1.870010e-05 & 6.114980e-05 & 8.260690e-06 & 6.257270e-05 & 1.990281e-04 & 6.867232e-05 & 2.681214e-05\\\\\n",
       "\tMacrophage & 3.298288e-07 & 1.411043e-06 & 9.989069e-09 & 7.210862e-04 & 1.376798e-06 & 1.566517e-05 & 6.532266e-09 & 1.496544e-08 & 1.015744e-08 & 4.821042e-05 & ⋯ & 1.604892e-05 & 1.957888e-05 & 2.943255e-05 & 5.904993e-05 & 4.087582e-05 & 2.106199e-06 & 3.832560e-05 & 5.589237e-04 & 4.206303e-05 & 2.676705e-05\\\\\n",
       "\tEndothelial & 1.282867e-07 & 9.413568e-07 & 6.884161e-08 & 1.450910e-03 & 4.211413e-06 & 3.825659e-05 & 4.536466e-06 & 1.515922e-04 & 9.501013e-09 & 2.822296e-05 & ⋯ & 1.327456e-05 & 1.881648e-05 & 2.625536e-05 & 1.812981e-05 & 5.772141e-05 & 7.044692e-06 & 6.718225e-05 & 3.190477e-04 & 1.009169e-04 & 3.883224e-05\\\\\n",
       "\tT cell & 3.851666e-07 & 1.088591e-06 & 1.762161e-07 & 3.269938e-05 & 1.162382e-06 & 8.054513e-05 & 6.696823e-07 & 1.499636e-06 & 2.875079e-07 & 1.771516e-05 & ⋯ & 1.541649e-05 & 1.309156e-05 & 3.134094e-05 & 4.300053e-05 & 9.319480e-05 & 2.503748e-05 & 6.932394e-05 & 2.367922e-04 & 1.188224e-04 & 4.305001e-05\\\\\n",
       "\tDendritic & 9.554070e-07 & 6.553169e-08 & 9.309546e-08 & 3.239208e-05 & 1.002456e-07 & 2.712358e-05 & 4.277995e-09 & 1.690812e-08 & 8.519275e-09 & 6.941841e-06 & ⋯ & 3.615964e-05 & 1.543686e-05 & 4.610866e-05 & 1.262511e-05 & 4.199085e-05 & 2.104540e-05 & 3.008003e-05 & 3.829456e-04 & 9.742747e-05 & 6.903309e-05\\\\\n",
       "\tMast & 7.083485e-07 & 4.897996e-06 & 5.085302e-07 & 1.455733e-04 & 5.888258e-06 & 9.364647e-05 & 9.013286e-06 & 6.846619e-06 & 9.594516e-09 & 1.842756e-05 & ⋯ & 1.354589e-05 & 6.861964e-06 & 2.406780e-05 & 1.090380e-05 & 8.286390e-05 & 8.903383e-06 & 5.111216e-05 & 9.390497e-05 & 5.997305e-05 & 3.087020e-05\\\\\n",
       "\\end{tabular}\n"
      ],
      "text/markdown": [
       "\n",
       "A matrix: 9 × 18234 of type dbl\n",
       "\n",
       "| <!--/--> | ENSG00000121410 | ENSG00000268895 | ENSG00000148584 | ENSG00000175899 | ENSG00000245105 | ENSG00000166535 | ENSG00000256069 | ENSG00000128274 | ENSG00000118017 | ENSG00000094914 | ⋯ | ENSG00000153975 | ENSG00000086827 | ENSG00000174442 | ENSG00000122952 | ENSG00000070476 | ENSG00000203995 | ENSG00000162378 | ENSG00000159840 | ENSG00000074755 | ENSG00000036549 |\n",
       "|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|\n",
       "| Fibroblast | 4.790526e-07 | 3.048030e-06 | 5.382811e-08 | 1.240567e-03 | 2.094833e-06 | 3.366184e-05 | 7.236724e-09 | 1.393013e-04 | 2.281876e-07 | 3.339089e-05 | ⋯ | 6.564508e-06 | 1.760142e-05 | 1.410649e-05 | 4.544236e-06 | 4.750947e-05 | 3.636425e-06 | 6.375454e-05 | 4.416710e-04 | 9.048196e-05 | 3.904093e-05 |\n",
       "| B cell | 1.655977e-06 | 3.033846e-06 | 3.499550e-08 | 8.575522e-06 | 2.838517e-07 | 3.172259e-05 | 5.312870e-09 | 1.333111e-08 | 8.352407e-09 | 4.948197e-05 | ⋯ | 1.283167e-05 | 2.093139e-05 | 3.263562e-05 | 2.451176e-05 | 5.335222e-05 | 1.418179e-05 | 4.343860e-05 | 6.161845e-05 | 7.989676e-05 | 2.023588e-05 |\n",
       "| myocyte | 1.071422e-09 | 2.065976e-09 | 2.715623e-09 | 1.057379e-03 | 7.556871e-09 | 5.537073e-06 | 1.350077e-08 | 5.086130e-05 | 6.752496e-09 | 7.624092e-05 | ⋯ | 1.688090e-06 | 1.007480e-05 | 1.787889e-06 | 5.928562e-09 | 5.594272e-05 | 2.477242e-06 | 4.152031e-05 | 1.598354e-04 | 1.092872e-04 | 2.347115e-05 |\n",
       "| <!----> | 1.844932e-07 | 9.019386e-07 | 7.031525e-08 | 3.637507e-04 | 8.086174e-07 | 2.698824e-04 | 1.070870e-08 | 8.383799e-05 | 6.920277e-09 | 2.908657e-05 | ⋯ | 8.870377e-06 | 1.686399e-05 | 1.544228e-05 | 1.870010e-05 | 6.114980e-05 | 8.260690e-06 | 6.257270e-05 | 1.990281e-04 | 6.867232e-05 | 2.681214e-05 |\n",
       "| Macrophage | 3.298288e-07 | 1.411043e-06 | 9.989069e-09 | 7.210862e-04 | 1.376798e-06 | 1.566517e-05 | 6.532266e-09 | 1.496544e-08 | 1.015744e-08 | 4.821042e-05 | ⋯ | 1.604892e-05 | 1.957888e-05 | 2.943255e-05 | 5.904993e-05 | 4.087582e-05 | 2.106199e-06 | 3.832560e-05 | 5.589237e-04 | 4.206303e-05 | 2.676705e-05 |\n",
       "| Endothelial | 1.282867e-07 | 9.413568e-07 | 6.884161e-08 | 1.450910e-03 | 4.211413e-06 | 3.825659e-05 | 4.536466e-06 | 1.515922e-04 | 9.501013e-09 | 2.822296e-05 | ⋯ | 1.327456e-05 | 1.881648e-05 | 2.625536e-05 | 1.812981e-05 | 5.772141e-05 | 7.044692e-06 | 6.718225e-05 | 3.190477e-04 | 1.009169e-04 | 3.883224e-05 |\n",
       "| T cell | 3.851666e-07 | 1.088591e-06 | 1.762161e-07 | 3.269938e-05 | 1.162382e-06 | 8.054513e-05 | 6.696823e-07 | 1.499636e-06 | 2.875079e-07 | 1.771516e-05 | ⋯ | 1.541649e-05 | 1.309156e-05 | 3.134094e-05 | 4.300053e-05 | 9.319480e-05 | 2.503748e-05 | 6.932394e-05 | 2.367922e-04 | 1.188224e-04 | 4.305001e-05 |\n",
       "| Dendritic | 9.554070e-07 | 6.553169e-08 | 9.309546e-08 | 3.239208e-05 | 1.002456e-07 | 2.712358e-05 | 4.277995e-09 | 1.690812e-08 | 8.519275e-09 | 6.941841e-06 | ⋯ | 3.615964e-05 | 1.543686e-05 | 4.610866e-05 | 1.262511e-05 | 4.199085e-05 | 2.104540e-05 | 3.008003e-05 | 3.829456e-04 | 9.742747e-05 | 6.903309e-05 |\n",
       "| Mast | 7.083485e-07 | 4.897996e-06 | 5.085302e-07 | 1.455733e-04 | 5.888258e-06 | 9.364647e-05 | 9.013286e-06 | 6.846619e-06 | 9.594516e-09 | 1.842756e-05 | ⋯ | 1.354589e-05 | 6.861964e-06 | 2.406780e-05 | 1.090380e-05 | 8.286390e-05 | 8.903383e-06 | 5.111216e-05 | 9.390497e-05 | 5.997305e-05 | 3.087020e-05 |\n",
       "\n"
      ],
      "text/plain": [
       "            ENSG00000121410 ENSG00000268895 ENSG00000148584 ENSG00000175899\n",
       "Fibroblast  4.790526e-07    3.048030e-06    5.382811e-08    1.240567e-03   \n",
       "B cell      1.655977e-06    3.033846e-06    3.499550e-08    8.575522e-06   \n",
       "myocyte     1.071422e-09    2.065976e-09    2.715623e-09    1.057379e-03   \n",
       "            1.844932e-07    9.019386e-07    7.031525e-08    3.637507e-04   \n",
       "Macrophage  3.298288e-07    1.411043e-06    9.989069e-09    7.210862e-04   \n",
       "Endothelial 1.282867e-07    9.413568e-07    6.884161e-08    1.450910e-03   \n",
       "T cell      3.851666e-07    1.088591e-06    1.762161e-07    3.269938e-05   \n",
       "Dendritic   9.554070e-07    6.553169e-08    9.309546e-08    3.239208e-05   \n",
       "Mast        7.083485e-07    4.897996e-06    5.085302e-07    1.455733e-04   \n",
       "            ENSG00000245105 ENSG00000166535 ENSG00000256069 ENSG00000128274\n",
       "Fibroblast  2.094833e-06    3.366184e-05    7.236724e-09    1.393013e-04   \n",
       "B cell      2.838517e-07    3.172259e-05    5.312870e-09    1.333111e-08   \n",
       "myocyte     7.556871e-09    5.537073e-06    1.350077e-08    5.086130e-05   \n",
       "            8.086174e-07    2.698824e-04    1.070870e-08    8.383799e-05   \n",
       "Macrophage  1.376798e-06    1.566517e-05    6.532266e-09    1.496544e-08   \n",
       "Endothelial 4.211413e-06    3.825659e-05    4.536466e-06    1.515922e-04   \n",
       "T cell      1.162382e-06    8.054513e-05    6.696823e-07    1.499636e-06   \n",
       "Dendritic   1.002456e-07    2.712358e-05    4.277995e-09    1.690812e-08   \n",
       "Mast        5.888258e-06    9.364647e-05    9.013286e-06    6.846619e-06   \n",
       "            ENSG00000118017 ENSG00000094914 ⋯ ENSG00000153975 ENSG00000086827\n",
       "Fibroblast  2.281876e-07    3.339089e-05    ⋯ 6.564508e-06    1.760142e-05   \n",
       "B cell      8.352407e-09    4.948197e-05    ⋯ 1.283167e-05    2.093139e-05   \n",
       "myocyte     6.752496e-09    7.624092e-05    ⋯ 1.688090e-06    1.007480e-05   \n",
       "            6.920277e-09    2.908657e-05    ⋯ 8.870377e-06    1.686399e-05   \n",
       "Macrophage  1.015744e-08    4.821042e-05    ⋯ 1.604892e-05    1.957888e-05   \n",
       "Endothelial 9.501013e-09    2.822296e-05    ⋯ 1.327456e-05    1.881648e-05   \n",
       "T cell      2.875079e-07    1.771516e-05    ⋯ 1.541649e-05    1.309156e-05   \n",
       "Dendritic   8.519275e-09    6.941841e-06    ⋯ 3.615964e-05    1.543686e-05   \n",
       "Mast        9.594516e-09    1.842756e-05    ⋯ 1.354589e-05    6.861964e-06   \n",
       "            ENSG00000174442 ENSG00000122952 ENSG00000070476 ENSG00000203995\n",
       "Fibroblast  1.410649e-05    4.544236e-06    4.750947e-05    3.636425e-06   \n",
       "B cell      3.263562e-05    2.451176e-05    5.335222e-05    1.418179e-05   \n",
       "myocyte     1.787889e-06    5.928562e-09    5.594272e-05    2.477242e-06   \n",
       "            1.544228e-05    1.870010e-05    6.114980e-05    8.260690e-06   \n",
       "Macrophage  2.943255e-05    5.904993e-05    4.087582e-05    2.106199e-06   \n",
       "Endothelial 2.625536e-05    1.812981e-05    5.772141e-05    7.044692e-06   \n",
       "T cell      3.134094e-05    4.300053e-05    9.319480e-05    2.503748e-05   \n",
       "Dendritic   4.610866e-05    1.262511e-05    4.199085e-05    2.104540e-05   \n",
       "Mast        2.406780e-05    1.090380e-05    8.286390e-05    8.903383e-06   \n",
       "            ENSG00000162378 ENSG00000159840 ENSG00000074755 ENSG00000036549\n",
       "Fibroblast  6.375454e-05    4.416710e-04    9.048196e-05    3.904093e-05   \n",
       "B cell      4.343860e-05    6.161845e-05    7.989676e-05    2.023588e-05   \n",
       "myocyte     4.152031e-05    1.598354e-04    1.092872e-04    2.347115e-05   \n",
       "            6.257270e-05    1.990281e-04    6.867232e-05    2.681214e-05   \n",
       "Macrophage  3.832560e-05    5.589237e-04    4.206303e-05    2.676705e-05   \n",
       "Endothelial 6.718225e-05    3.190477e-04    1.009169e-04    3.883224e-05   \n",
       "T cell      6.932394e-05    2.367922e-04    1.188224e-04    4.305001e-05   \n",
       "Dendritic   3.008003e-05    3.829456e-04    9.742747e-05    6.903309e-05   \n",
       "Mast        5.111216e-05    9.390497e-05    5.997305e-05    3.087020e-05   "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "res1$res$phi.env"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "9ffe1fb7",
   "metadata": {},
   "source": [
    "### Learning embeddings of tumor expression. Preferred in article. Choose optimum K using NMF. Initialize using the embedding provided by user.\n",
    "\n",
    "optimized the number of malignant bases from two to 12, and chose the number of gene programs (K) that yielded the best cophenetic score before a significant drop began. (K=4 for HNSCC)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 11,
   "id": "4eb60a32",
   "metadata": {
    "collapsed": true
   },
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "also installing the dependencies ‘pkgmaker’, ‘registry’, ‘rngtools’, ‘gridBase’, ‘doParallel’\n",
      "\n",
      "\n",
      "Updating HTML index of packages in '.Library'\n",
      "\n",
      "Making 'packages.html' ...\n",
      " done\n",
      "\n"
     ]
    }
   ],
   "source": [
    "install.packages(\"NMF\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 13,
   "id": "7aa0ba56",
   "metadata": {
    "collapsed": true
   },
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "also installing the dependency ‘bigmemory.sri’\n",
      "\n",
      "\n",
      "Updating HTML index of packages in '.Library'\n",
      "\n",
      "Making 'packages.html' ...\n",
      " done\n",
      "\n",
      "Loading required package: bigmemory\n",
      "\n",
      "Updating HTML index of packages in '.Library'\n",
      "\n",
      "Making 'packages.html' ...\n",
      " done\n",
      "\n",
      "Loading required package: synchronicity\n",
      "\n",
      "\n",
      "Attaching package: ‘synchronicity’\n",
      "\n",
      "\n",
      "The following object is masked from ‘package:bigmemory’:\n",
      "\n",
      "    shared.name\n",
      "\n",
      "\n",
      "The following object is masked from ‘package:Biobase’:\n",
      "\n",
      "    description\n",
      "\n",
      "\n"
     ]
    }
   ],
   "source": [
    "install.extras('NMF')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 14,
   "id": "072d5412",
   "metadata": {},
   "outputs": [],
   "source": [
    "library(NMF)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 15,
   "id": "ac600819",
   "metadata": {},
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "Timing stopped at: 24.11 20.69 44.19\n",
      "\n"
     ]
    }
   ],
   "source": [
    "Z.tum.norm <- t(res1$res$first.gibbs.res$Zkg.tum.norm)\n",
    "estim.Z.tum.norm <- nmf(Z.tum.norm, 2:12, nrun=30, seed=123456)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 19,
   "id": "7c0ee35c",
   "metadata": {},
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "NMF algorithm: 'brunet'\n",
      "\n",
      "Multiple runs: 200\n",
      "\n",
      "Mode: parallel (32/32 core(s))\n",
      "\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "\r",
      "Runs: |                                                        \r",
      "Runs: |                                                  |   0%"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "Timing stopped at: 1.693 14.14 987.3\n",
      "\n"
     ]
    }
   ],
   "source": [
    "resK4 <- nmf(Z.tum.norm,4,nrun=200,.opt='vp50',seed=123456)\n",
    "phi.tumK4 <- t(basis(resK4))"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "id": "d717c71a",
   "metadata": {},
   "outputs": [],
   "source": [
    "res1.k4 <- learn.embedding.withPhiTum(ted.res=res1, phi.tum=phi.tumK4,\n",
    "                                     EM.maxit=50, n.cores=20, compute.posterior=T)"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "ed100ce8",
   "metadata": {},
   "source": [
    "# pathway initialized using hierarchical clustering "
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "id": "55021f3f",
   "metadata": {},
   "outputs": [],
   "source": []
  }
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